Clinical Features	Time to Death		YEARS_TO_BIRTH		PATHOLOGIC_STAGE		PATHOLOGY_T_STAGE		PATHOLOGY_N_STAGE		PATHOLOGY_M_STAGE		GENDER		KARNOFSKY_PERFORMANCE_SCORE		HISTOLOGICAL_TYPE		NUMBER_PACK_YEARS_SMOKED		YEAR_OF_TOBACCO_SMOKING_ONSET		RACE		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
FAM18B2	35 (5%)	628	0.40453	1	0.60265	1	0.70189	1	0.87614	1	0.01388	0.245	1	1	0.85531	1	0.2751	1	9.9999e-06	0.000926	0.80586	1	NA	NA	0.0069799	0.181	1	1
TP53	35 (5%)	628	0.92326	1	0.24454	1	0.0079399	0.19	0.0053599	0.152	0.064479	0.583	1	1	0.36094	1	0.26717	1	9.9999e-06	0.000926	0.3917	1	1	1	0.19829	0.988	1	1
PTEN	26 (4%)	637	0.7141	1	0.90266	1	0.26204	1	0.34101	1	0.16207	0.91	0.34595	1	0.83405	1	0.57903	1	0.095729	0.728	0.88354	1	0.92267	1	0.50161	1	1	1
KDM5C	28 (4%)	635	0.037881	0.466	0.041344	0.466	0.63498	1	0.70321	1	1	1	0.77948	1	0.0071005	0.181	NA	NA	0.02695	0.384	NA	NA	NA	NA	1	1	0.3849	1
SETD2	56 (8%)	607	0.08008	0.674	0.012845	0.233	0.063569	0.583	0.070529	0.63	0.42407	1	0.3004	1	0.55833	1	0.42034	1	0.14038	0.857	NA	NA	NA	NA	0.81732	1	0.49744	1
PBRM1	138 (21%)	525	0.35477	1	0.010802	0.233	0.55507	1	0.46034	1	0.04199	0.466	0.4841	1	0.61632	1	0.77597	1	9.9999e-06	0.000926	NA	NA	NA	NA	0.0126	0.233	0.65021	1
NEFH	16 (2%)	647	0.31122	1	0.37439	1	0.27634	1	0.44348	1	1	1	0.32438	1	0.59596	1	0.91982	1	0.00317	0.0979	0.28047	1	NA	NA	0.12525	0.793	1	1
VHL	195 (29%)	468	0.016191	0.267	0.063812	0.583	0.44614	1	0.2406	1	0.02532	0.368	0.79956	1	0.24465	1	0.17409	0.921	9.9999e-06	0.000926	NA	NA	NA	NA	9.9999e-06	0.000926	1	1
MET	19 (3%)	644	0.57282	1	0.81745	1	0.46296	1	0.92539	1	0.099159	0.728	1	1	1	1	NA	NA	9.9999e-06	0.000926	0.2402	1	0.7751	1	0.14324	0.857	1	1
HNRNPM	12 (2%)	651	0.31536	1	0.4863	1	0.45869	1	0.060089	0.578	0.34289	1	0.60039	1	0.55831	1	0.64425	1	2e-05	0.00165	NA	NA	NA	NA	0.26927	1	1	1
NF2	16 (2%)	647	0.099213	0.728	0.21788	1	0.03376	0.455	0.12076	0.785	3e-05	0.00222	0.042411	0.466	0.79475	1	0.28761	1	0.00314	0.0979	NA	NA	NA	NA	0.062009	0.582	0.20753	0.988
TDG	5 (1%)	658	0.24499	1	0.44191	1	1	1	0.11605	0.785	0.34428	1	1	1	0.66409	1	NA	NA	0.00184	0.0729	NA	NA	NA	NA	0.47746	1	1	1
MUC5B	32 (5%)	631	0.56763	1	0.91369	1	0.44167	1	0.46135	1	0.19603	0.988	0.22863	1	0.45225	1	0.24246	1	9.9999e-06	0.000926	1	1	0.84672	1	0.40119	1	1	1
ZNF814	13 (2%)	650	0.20205	0.988	0.25197	1	0.13349	0.824	0.25074	1	0.4313	1	1	1	0.041383	0.466	NA	NA	0.00046	0.0262	NA	NA	NA	NA	0.3319	1	1	1
CSGALNACT2	8 (1%)	655	0.11398	0.782	0.4979	1	0.75062	1	0.49486	1	1	1	0.60039	1	0.45725	1	NA	NA	0.00312	0.0979	NA	NA	NA	NA	0.12185	0.785	1	1
GPR50	5 (1%)	658	0.43998	1	0.32028	1	0.76113	1	0.85206	1	NA	NA	1	1	0.34659	1	NA	NA	0.60607	1	NA	NA	NA	NA	0.47747	1	1	1
STAG2	14 (2%)	649	0.99571	1	0.015785	0.266	0.15969	0.909	0.097429	0.728	1	1	0.66421	1	0.25848	1	NA	NA	0.17	0.921	NA	NA	NA	NA	0.49283	1	1	1
NFE2L2	10 (2%)	653	0.94411	1	0.011842	0.233	0.73746	1	0.77866	1	1	1	1	1	1	1	NA	NA	0.4656	1	NA	NA	NA	NA	0.40525	1	1	1
KDELR3	6 (1%)	657	0.58221	1	0.82713	1	0.27489	1	0.04274	0.466	1	1	1	1	0.66996	1	NA	NA	0.076239	0.656	NA	NA	NA	NA	0.54172	1	1	1
ATM	16 (2%)	647	0.47141	1	0.16936	0.921	0.0098599	0.228	0.0213	0.322	1	1	0.43755	1	0.43518	1	NA	NA	0.12502	0.793	NA	NA	NA	NA	0.55651	1	0.49648	1
MTOR	32 (5%)	631	0.077053	0.656	0.046074	0.481	0.44393	1	0.6993	1	1	1	0.17672	0.929	0.012176	0.233	0.031883	0.438	0.01544	0.266	NA	NA	NA	NA	0.875	1	0.71052	1
EGFR	6 (1%)	657	0.051536	0.516	0.30121	1	0.01217	0.233	0.00252	0.0889	0.43149	1	0.20931	0.988	0.66996	1	NA	NA	0.33787	1	NA	NA	NA	NA	1	1	1	1
SLC6A14	5 (1%)	658	0.79322	1	0.59047	1	0.21663	1	0.17288	0.921	0.090329	0.719	1	1	0.34659	1	NA	NA	0.24891	1	NA	NA	NA	NA	1	1	1	1
PIK3CA	12 (2%)	651	0.91446	1	0.21372	1	0.20645	0.988	0.20184	0.988	1	1	0.20217	0.988	0.12142	0.785	NA	NA	0.47988	1	NA	NA	NA	NA	0.70189	1	0.49648	1
EMG1	4 (1%)	659	0.20371	0.988	0.93185	1	0.52706	1	0.25474	1	NA	NA	1	1	1	1	NA	NA	0.72286	1	NA	NA	NA	NA	1	1	1	1
RIMBP3	5 (1%)	658	0.31803	1	0.31515	1	0.62493	1	0.090599	0.719	1	1	1	1	0.34659	1	NA	NA	0.082949	0.689	NA	NA	NA	NA	1	1	1	1
RAI1	7 (1%)	656	0.80163	1	0.70856	1	0.25689	1	0.1076	0.759	1	1	0.46455	1	0.24183	1	NA	NA	0.16069	0.909	NA	NA	NA	NA	1	1	1	1
FAM160B2	4 (1%)	659	0.22293	1	0.73132	1	0.31155	1	0.6523	1	NA	NA	0.37376	1	0.61164	1	NA	NA	0.38705	1	NA	NA	NA	NA	1	1	1	1
ZNF598	11 (2%)	652	0.41878	1	0.49983	1	0.64797	1	0.92777	1	0.01982	0.306	0.10137	0.729	0.34606	1	0.083742	0.689	9.9999e-06	0.000926	0.17897	0.934	NA	NA	0.2675	1	0.49648	1
KDM6A	10 (2%)	653	0.11203	0.776	0.012724	0.233	0.42187	1	0.92225	1	NA	NA	0.60089	1	0.74369	1	NA	NA	0.0079399	0.19	NA	NA	NA	NA	0.00011	0.00741	1	1
DPCR1	8 (1%)	655	0.68631	1	0.23637	1	0.22217	1	0.73562	1	NA	NA	0.04172	0.466	0.72094	1	NA	NA	0.74301	1	NA	NA	NA	NA	0.64907	1	1	1
CYP4F11	5 (1%)	658	0.89376	1	0.47911	1	0.14179	0.857	0.0444	0.477	0.50613	1	0.46455	1	1	1	NA	NA	0.34301	1	NA	NA	NA	NA	1	1	1	1
STAM	6 (1%)	657	0.70245	1	0.43036	1	0.00055999	0.0296	0.00202	0.0748	0.04575	0.481	0.10137	0.729	0.66996	1	NA	NA	0.075069	0.656	NA	NA	NA	NA	1	1	0.036898	0.466
NUDT11	5 (1%)	658	0.49844	1	0.18997	0.978	0.68844	1	0.49732	1	NA	NA	1	1	0.66409	1	NA	NA	1	1	NA	NA	NA	NA	1	1	1	1
PARD6B	5 (1%)	658	0.66835	1	0.049916	0.514	0.42667	1	0.49466	1	NA	NA	1	1	0.17008	0.921	NA	NA	0.17349	0.921	NA	NA	NA	NA	0.47727	1	1	1
RHEB	3 (0%)	660	0.81043	1	0.84001	1	0.69007	1	0.74027	1	NA	NA	0.2678	1	0.27517	1	NA	NA	1	1	NA	NA	NA	NA	0.31958	1	1	1
SLC16A1	3 (0%)	660	0.38702	1	0.19434	0.988	1	1	1	1	NA	NA	1	1	1	1	NA	NA	1	1	NA	NA	NA	NA	0.3191	1	0.18474	0.957
SKI	9 (1%)	654	0.59157	1	0.72471	1	0.54626	1	0.69823	1	0.4296	1	1	1	0.72584	1	NA	NA	0.00187	0.0729	0.7331	1	NA	NA	0.26549	1	1	1
THBS1	10 (2%)	653	0.98487	1	0.15387	0.891	0.78667	1	1	1	NA	NA	0.60089	1	0.50684	1	NA	NA	0.46921	1	NA	NA	NA	NA	1	1	1	1
SH3BP2	4 (1%)	659	0.53237	1	0.57877	1	1	1	0.65242	1	NA	NA	1	1	0.61164	1	NA	NA	0.099009	0.728	NA	NA	NA	NA	0.40535	1	1	1
NASP	4 (1%)	659	0.20178	0.988	0.33621	1	0.21942	1	0.33172	1	NA	NA	1	1	0.12144	0.785	NA	NA	0.03582	0.466	NA	NA	NA	NA	1	1	0.23863	1
FAT1	21 (3%)	642	0.41155	1	0.3999	1	0.32761	1	0.26586	1	0.2906	1	1	1	0.81626	1	NA	NA	0.00061999	0.0301	0.83653	1	NA	NA	0.061429	0.582	0.62151	1
CACNA1C	17 (3%)	646	0.93587	1	0.99434	1	0.056899	0.555	0.50613	1	0.0192	0.306	0.0055375	0.152	0.79866	1	0.80822	1	0.3164	1	NA	NA	NA	NA	0.56944	1	0.59138	1
PCK1	5 (1%)	658	0.16636	0.921	0.44682	1	0.67976	1	0.34372	1	1	1	1	1	1	1	NA	NA	1	1	NA	NA	NA	NA	0.47751	1	1	1
TPPP	3 (0%)	660	0.7885	1	0.46068	1	1	1	1	1	NA	NA	1	1	0.040853	0.466	NA	NA	0.27263	1	NA	NA	NA	NA	0.01971	0.306	1	1
MLL3	38 (6%)	625	0.93486	1	0.42831	1	0.26692	1	0.22053	1	0.6315	1	1	1	0.37956	1	0.31427	1	0.00064999	0.0301	0.61068	1	NA	NA	0.0102	0.229	0.7109	1
PAM	4 (1%)	659	0.23066	1	0.9486	1	0.77601	1	1	1	0.34475	1	1	1	1	1	NA	NA	0.097909	0.728	NA	NA	0.36497	1	0.32297	1	1	1
GAPDHS	5 (1%)	658	0.29974	1	0.40244	1	0.91541	1	0.6039	1	NA	NA	1	1	1	1	NA	NA	0.25015	1	NA	NA	NA	NA	0.17058	0.921	1	1
TMCO3	7 (1%)	656	0.46415	1	0.55446	1	0.34198	1	0.6247	1	0.4295	1	1	1	0.24183	1	NA	NA	1	1	NA	NA	NA	NA	0.03	0.419	0.28906	1
RPL7A	3 (0%)	660	0.75726	1	0.20444	0.988	0.58748	1	1	1	NA	NA	0.14418	0.857	0.555	1	NA	NA	0.0228	0.338	NA	NA	NA	NA	0.32296	1	1	1
ARHGAP35	7 (1%)	656	0.11718	0.785	0.8537	1	0.1067	0.759	0.23364	1	1	1	0.20931	0.988	0.69759	1	NA	NA	0.84861	1	NA	NA	NA	NA	0.04068	0.466	1	1
AHNAK2	33 (5%)	630	0.81472	1	0.22123	1	0.15549	0.893	0.10988	0.768	0.14463	0.857	0.56384	1	0.57545	1	0.77261	1	0.00172	0.0729	0.69152	1	0.1307	0.814	0.00396	0.117	0.64841	1
JMJD1C	10 (2%)	653	0.1504	0.878	0.88832	1	1	1	0.84578	1	1	1	1	1	1	1	NA	NA	0.35449	1	NA	NA	NA	NA	1	1	0.091267	0.719
TTLL6	6 (1%)	657	0.66732	1	0.12134	0.785	0.04073	0.466	0.01288	0.233	1	1	1	1	0.42098	1	NA	NA	0.076319	0.656	NA	NA	NA	NA	0.54178	1	1	1
AMAC1L3	8 (1%)	655	0.12779	0.802	0.29988	1	0.14719	0.866	0.27283	1	1	1	1	1	0.72094	1	NA	NA	0.00024	0.0148	NA	NA	NA	NA	0.59887	1	1	1
TRAPPC9	5 (1%)	658	0.30871	1	0.7098	1	0.7616	1	0.85343	1	NA	NA	1	1	0.05084	0.516	NA	NA	0.053859	0.532	NA	NA	NA	NA	0.40809	1	1	1
MED16	4 (1%)	659	0.035202	0.466	0.84238	1	0.40617	1	0.33023	1	0.088189	0.718	1	1	0.61164	1	NA	NA	0.098009	0.728	NA	NA	NA	NA	1	1	1	1