PARADIGM pathway analysis of mRNASeq expression data
Lung Adenocarcinoma (Primary solid tumor)
21 August 2015  |  analyses__2015_08_21
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2015): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1Z60NB5
- Overview
+ Introduction
- Summary

There were 42 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Glypican 2 network 193
Angiopoietin receptor Tie2-mediated signaling 153
Aurora B signaling 127
FOXM1 transcription factor network 125
Signaling events mediated by the Hedgehog family 103
Aurora C signaling 77
Endothelins 74
HIF-1-alpha transcription factor network 70
Visual signal transduction: Cones 68
PLK1 signaling events 68
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data