PARADIGM pathway analysis of mRNASeq expression data
Pancreatic Adenocarcinoma (Primary solid tumor)
21 August 2015  |  analyses__2015_08_21
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2015): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C17P8XNV
- Overview
+ Introduction
- Summary

There were 49 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
FOXA2 and FOXA3 transcription factor networks 38
IL23-mediated signaling events 38
HIF-1-alpha transcription factor network 35
TCGA08_retinoblastoma 32
Signaling events mediated by the Hedgehog family 28
Nephrin/Neph1 signaling in the kidney podocyte 27
amb2 Integrin signaling 25
IL4-mediated signaling events 23
TCR signaling in naïve CD8+ T cells 21
IL12-mediated signaling events 20
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data