Clustering of copy number data by peak region with threshold value: consensus NMF
Thyroid Adenocarcinoma (Primary solid tumor)
21 August 2015
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analyses__2015_08_21
Maintainer Information
Citation Information
Maintained by Hailei Zhang
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2015):
Clustering of copy number data by peak region with threshold value: consensus NMF.
Broad Institute of MIT and Harvard.
doi:10.7908/C1FJ2G22
Overview
Introduction
Summary
The most robust consensus NMF clustering of 499 samples using the 107 copy number focal regions was identified for k = 3 clusters. We computed the clustering for k = 2 to k = 8 and used the cophenetic correlation coefficient to determine the best solution.
Results
Copy number focal events of molecular subtypes
Consensus and correlation matrix
Silhouette widths
Samples assignment with silhouette width
Marker focal events of each subtype
Methods & Data
Copyright © 2015
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.