This pipeline computes the correlation between significant copy number variation (cnv focal) genes and molecular subtypes.
Testing the association between copy number variation 73 focal events and 10 molecular subtypes across 408 patients, 331 significant findings detected with P value < 0.05 and Q value < 0.25.
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amp_1p34.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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amp_1q21.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_1q23.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_2p25.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_3p25.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_3q26.33 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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amp_4p16.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_4q13.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_5p15.33 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_6p22.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CNMF'.
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amp_6q21 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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amp_6q23.3 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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amp_7p21.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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amp_7p11.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'RPPA_CNMF'.
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amp_8p11.23 cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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amp_8p11.21 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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amp_8q22.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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amp_8q24.21 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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amp_9p24.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_10p14 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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amp_11p13 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_11q13.3 cnv correlated to 'CN_CNMF'.
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amp_11q22.2 cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_12p12.1 cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_12q15 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_13q22.1 cnv correlated to 'CN_CNMF'.
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amp_16p13.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
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amp_16p11.2 cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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amp_16q22.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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amp_17p11.2 cnv correlated to 'CN_CNMF'.
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amp_17q11.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_17q12 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_17q23.3 cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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amp_19q12 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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amp_19q13.43 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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amp_20q11.21 cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_22q12.2 cnv correlated to 'CN_CNMF'.
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del_1p36.11 cnv correlated to 'METHLYATION_CNMF'.
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del_1q32.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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del_2q22.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
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del_2q34 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CNMF'.
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del_2q37.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CNMF'.
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del_3p14.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_4q22.1 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_4q34.2 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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del_5q12.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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del_6p25.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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del_6q21 cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_6q27 cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_7q36.3 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_8p23.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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del_8p21.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_9p23 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_9p21.3 cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_9q22.33 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_10p11.21 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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del_10q23.31 cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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del_11p15.5 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_11q23.3 cnv correlated to 'CN_CNMF'.
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del_11q25 cnv correlated to 'CN_CNMF'.
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del_12p13.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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del_12q24.33 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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del_13q14.2 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_14q24.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_15q13.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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del_16p13.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CNMF'.
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del_16q23.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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del_17p12 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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del_18q23 cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_19p13.3 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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del_22q13.32 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_xq21.33 cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 73 focal events and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 331 significant findings detected.
|
Clinical Features |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| amp 4p16 3 | 74 (18%) | 334 |
0.0283 (0.0714) |
0.03 (0.0738) |
0.00373 (0.015) |
0.0002 (0.00142) |
0.0179 (0.0501) |
6e-05 (0.000487) |
0.00026 (0.00177) |
0.00124 (0.00612) |
0.0217 (0.0582) |
0.00202 (0.00888) |
| amp 3p25 2 | 190 (47%) | 218 |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
0.224 (0.334) |
0.0265 (0.0681) |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
0.00012 (0.000903) |
0.00012 (0.000903) |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
| amp 9p24 1 | 88 (22%) | 320 |
1e-05 (9.73e-05) |
0.00406 (0.0162) |
0.0309 (0.0751) |
0.00909 (0.0299) |
0.0237 (0.062) |
0.00167 (0.00767) |
0.00792 (0.0275) |
0.495 (0.585) |
0.00015 (0.00109) |
0.00098 (0.005) |
| amp 11p13 | 51 (12%) | 357 |
1e-05 (9.73e-05) |
0.00361 (0.0147) |
0.00147 (0.00697) |
0.0363 (0.0855) |
0.025 (0.0652) |
0.00084 (0.00451) |
0.00079 (0.00434) |
0.713 (0.775) |
0.0308 (0.0751) |
0.00031 (0.00199) |
| del 3p14 2 | 117 (29%) | 291 |
9e-05 (0.000692) |
0.0278 (0.0708) |
0.00015 (0.00109) |
0.0104 (0.033) |
1e-05 (9.73e-05) |
4e-05 (0.000348) |
0.00094 (0.0049) |
0.217 (0.33) |
0.00028 (0.00186) |
0.0002 (0.00142) |
| del 9p23 | 177 (43%) | 231 |
1e-05 (9.73e-05) |
0.00098 (0.005) |
0.0216 (0.0582) |
0.00463 (0.0177) |
0.00046 (0.00275) |
0.00024 (0.00167) |
0.00272 (0.0115) |
0.0905 (0.169) |
3e-05 (0.000264) |
0.00286 (0.012) |
| del 9q22 33 | 178 (44%) | 230 |
2e-05 (0.000182) |
2e-05 (0.000182) |
0.00036 (0.00223) |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
0.329 (0.438) |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
| del 11p15 5 | 211 (52%) | 197 |
1e-05 (9.73e-05) |
0.00067 (0.00382) |
0.609 (0.682) |
0.00023 (0.00161) |
0.00293 (0.0122) |
1e-05 (9.73e-05) |
0.00018 (0.0013) |
0.0182 (0.0506) |
0.00081 (0.00438) |
0.00188 (0.00837) |
| del 22q13 32 | 188 (46%) | 220 |
1e-05 (9.73e-05) |
0.00199 (0.0088) |
0.0297 (0.0738) |
0.00109 (0.00549) |
0.00076 (0.0042) |
0.00126 (0.00613) |
0.0427 (0.0968) |
0.589 (0.664) |
0.0018 (0.00811) |
0.0166 (0.047) |
| amp 1q23 3 | 216 (53%) | 192 |
1e-05 (9.73e-05) |
0.0409 (0.094) |
0.0605 (0.128) |
0.858 (0.893) |
0.0285 (0.0716) |
0.0252 (0.0654) |
0.00156 (0.00735) |
0.0008 (0.00436) |
0.0447 (0.101) |
0.0108 (0.0336) |
| amp 2p25 1 | 152 (37%) | 256 |
1e-05 (9.73e-05) |
2e-05 (0.000182) |
0.219 (0.331) |
0.624 (0.697) |
0.00034 (0.00214) |
2e-05 (0.000182) |
0.00521 (0.0193) |
0.00802 (0.0276) |
0.0379 (0.0884) |
0.00054 (0.00313) |
| amp 5p15 33 | 206 (50%) | 202 |
1e-05 (9.73e-05) |
0.0611 (0.128) |
0.00054 (0.00313) |
0.014 (0.0416) |
0.00815 (0.0279) |
0.0195 (0.0536) |
0.00472 (0.0178) |
0.0167 (0.0472) |
0.0841 (0.162) |
0.00463 (0.0177) |
| del 8p21 3 | 252 (62%) | 156 |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
0.118 (0.206) |
0.0336 (0.0804) |
0.00091 (0.00478) |
0.00865 (0.0291) |
0.0694 (0.14) |
0.00448 (0.0175) |
0.0497 (0.11) |
0.0419 (0.0955) |
| del 13q14 2 | 156 (38%) | 252 |
1e-05 (9.73e-05) |
0.279 (0.389) |
3e-05 (0.000264) |
0.0163 (0.0466) |
0.0161 (0.0462) |
0.00977 (0.0318) |
0.00104 (0.00527) |
0.354 (0.464) |
0.00721 (0.0257) |
0.00215 (0.0094) |
| del 14q24 1 | 137 (34%) | 271 |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
0.947 (0.956) |
0.0814 (0.158) |
0.00145 (0.00692) |
1e-05 (9.73e-05) |
0.00369 (0.015) |
0.00416 (0.0164) |
0.00161 (0.00748) |
0.00029 (0.00189) |
| amp 12q15 | 118 (29%) | 290 |
7e-05 (0.000562) |
0.378 (0.487) |
0.885 (0.915) |
0.578 (0.653) |
0.0255 (0.0658) |
0.0091 (0.0299) |
0.00397 (0.0159) |
0.0363 (0.0855) |
0.0026 (0.0111) |
8e-05 (0.000621) |
| del 4q22 1 | 161 (39%) | 247 |
1e-05 (9.73e-05) |
0.0996 (0.18) |
0.00112 (0.0056) |
0.0105 (0.0331) |
0.0179 (0.0501) |
0.00122 (0.00606) |
0.0133 (0.0399) |
0.82 (0.867) |
0.077 (0.15) |
0.0284 (0.0714) |
| amp 17q11 2 | 174 (43%) | 234 |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
0.106 (0.188) |
0.164 (0.267) |
0.00052 (0.00306) |
0.00031 (0.00199) |
0.063 (0.131) |
0.538 (0.619) |
0.00248 (0.0106) |
0.01 (0.0322) |
| amp 17q12 | 165 (40%) | 243 |
1e-05 (9.73e-05) |
0.0325 (0.0783) |
0.206 (0.318) |
0.148 (0.251) |
0.0941 (0.173) |
0.0352 (0.0835) |
0.0371 (0.0868) |
0.106 (0.188) |
0.00909 (0.0299) |
0.00909 (0.0299) |
| del 8p23 3 | 243 (60%) | 165 |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
0.123 (0.212) |
0.00841 (0.0285) |
6e-05 (0.000487) |
0.00013 (0.000968) |
0.213 (0.324) |
0.00979 (0.0318) |
0.155 (0.258) |
0.195 (0.306) |
| del 9p21 3 | 239 (59%) | 169 |
1e-05 (9.73e-05) |
0.194 (0.305) |
0.0539 (0.116) |
0.00591 (0.0215) |
0.00037 (0.00225) |
0.0223 (0.0595) |
0.238 (0.347) |
0.0913 (0.17) |
0.00414 (0.0164) |
0.0119 (0.0365) |
| del 12p13 1 | 68 (17%) | 340 |
0.0154 (0.0445) |
0.00514 (0.0192) |
0.838 (0.879) |
0.221 (0.333) |
1e-05 (9.73e-05) |
5e-05 (0.00042) |
0.00994 (0.0321) |
0.485 (0.579) |
0.0118 (0.0365) |
0.208 (0.32) |
| del 15q13 1 | 160 (39%) | 248 |
1e-05 (9.73e-05) |
0.00226 (0.00982) |
0.0934 (0.172) |
0.541 (0.621) |
0.00899 (0.0299) |
0.357 (0.466) |
0.0397 (0.0916) |
0.0104 (0.033) |
0.019 (0.0524) |
0.0584 (0.124) |
| amp 1q21 3 | 202 (50%) | 206 |
1e-05 (9.73e-05) |
0.00589 (0.0215) |
0.337 (0.445) |
0.635 (0.705) |
0.0093 (0.0304) |
0.116 (0.204) |
0.0133 (0.0399) |
0.0909 (0.169) |
0.692 (0.759) |
0.0351 (0.0835) |
| amp 7p21 1 | 201 (49%) | 207 |
1e-05 (9.73e-05) |
0.00359 (0.0147) |
0.0218 (0.0582) |
0.0932 (0.172) |
0.0133 (0.0399) |
0.0231 (0.061) |
0.0601 (0.127) |
0.312 (0.422) |
0.151 (0.255) |
0.154 (0.258) |
| amp 8q22 3 | 264 (65%) | 144 |
1e-05 (9.73e-05) |
8e-05 (0.000621) |
0.0124 (0.0375) |
0.834 (0.876) |
0.447 (0.546) |
0.254 (0.363) |
0.0992 (0.179) |
0.0337 (0.0804) |
0.0327 (0.0784) |
0.186 (0.294) |
| amp 8q24 21 | 254 (62%) | 154 |
1e-05 (9.73e-05) |
0.00125 (0.00612) |
0.00034 (0.00214) |
0.172 (0.277) |
0.386 (0.493) |
0.719 (0.78) |
0.0492 (0.109) |
0.0142 (0.0419) |
0.201 (0.312) |
0.24 (0.348) |
| amp 11q22 2 | 71 (17%) | 337 |
2e-05 (0.000182) |
0.391 (0.495) |
0.888 (0.915) |
0.413 (0.515) |
0.212 (0.324) |
0.164 (0.267) |
0.00091 (0.00478) |
0.0199 (0.0543) |
0.00026 (0.00177) |
0.0141 (0.0416) |
| del 5q12 1 | 202 (50%) | 206 |
1e-05 (9.73e-05) |
0.00141 (0.00677) |
0.0747 (0.148) |
0.269 (0.38) |
0.488 (0.581) |
0.00456 (0.0176) |
0.00182 (0.00815) |
0.0121 (0.0368) |
0.157 (0.259) |
0.0533 (0.116) |
| del 6q27 | 190 (47%) | 218 |
1e-05 (9.73e-05) |
0.0541 (0.116) |
0.213 (0.324) |
0.0816 (0.158) |
0.735 (0.792) |
0.0107 (0.0336) |
0.0137 (0.0409) |
0.0108 (0.0336) |
0.254 (0.363) |
0.00281 (0.0119) |
| del 18q23 | 179 (44%) | 229 |
1e-05 (9.73e-05) |
0.46 (0.559) |
0.829 (0.873) |
0.792 (0.845) |
0.929 (0.947) |
0.153 (0.257) |
0.00027 (0.00182) |
1e-05 (9.73e-05) |
0.00307 (0.0127) |
0.00439 (0.0172) |
| amp 3q26 33 | 218 (53%) | 190 |
1e-05 (9.73e-05) |
0.894 (0.92) |
0.0018 (0.00811) |
0.187 (0.294) |
0.159 (0.261) |
0.0226 (0.0599) |
0.0103 (0.0329) |
0.178 (0.284) |
0.282 (0.391) |
0.0769 (0.15) |
| amp 6p22 3 | 171 (42%) | 237 |
1e-05 (9.73e-05) |
5e-05 (0.00042) |
0.0459 (0.103) |
0.913 (0.936) |
0.00158 (0.00739) |
0.549 (0.626) |
0.274 (0.384) |
0.395 (0.498) |
0.332 (0.44) |
0.275 (0.385) |
| amp 10p14 | 182 (45%) | 226 |
1e-05 (9.73e-05) |
1e-05 (9.73e-05) |
0.252 (0.362) |
0.164 (0.267) |
0.00451 (0.0175) |
5e-05 (0.00042) |
0.154 (0.258) |
0.0679 (0.138) |
0.38 (0.489) |
0.168 (0.272) |
| amp 16q22 1 | 108 (26%) | 300 |
1e-05 (9.73e-05) |
0.563 (0.639) |
0.326 (0.436) |
0.27 (0.381) |
0.475 (0.573) |
0.00466 (0.0177) |
0.0517 (0.113) |
0.0147 (0.0429) |
0.0292 (0.0729) |
0.17 (0.275) |
| del 2q34 | 174 (43%) | 234 |
1e-05 (9.73e-05) |
0.00098 (0.005) |
0.00662 (0.0237) |
0.485 (0.579) |
0.00767 (0.0269) |
0.108 (0.193) |
0.503 (0.589) |
0.348 (0.457) |
0.525 (0.606) |
0.927 (0.946) |
| del 2q37 1 | 207 (51%) | 201 |
1e-05 (9.73e-05) |
0.00029 (0.00189) |
0.0434 (0.0981) |
0.602 (0.676) |
0.0255 (0.0658) |
0.0659 (0.135) |
0.236 (0.344) |
0.0725 (0.145) |
0.289 (0.397) |
0.335 (0.444) |
| del 6p25 3 | 106 (26%) | 302 |
1e-05 (9.73e-05) |
0.00037 (0.00225) |
0.0391 (0.0907) |
0.898 (0.922) |
0.0507 (0.111) |
0.0148 (0.0429) |
0.475 (0.573) |
0.405 (0.509) |
0.358 (0.466) |
0.845 (0.885) |
| del 6q21 | 190 (47%) | 218 |
1e-05 (9.73e-05) |
0.238 (0.347) |
0.145 (0.246) |
0.465 (0.564) |
0.886 (0.915) |
0.235 (0.344) |
0.00299 (0.0124) |
0.0147 (0.0429) |
0.256 (0.365) |
0.00625 (0.0226) |
| del 7q36 3 | 60 (15%) | 348 |
0.00051 (0.00303) |
0.521 (0.603) |
0.119 (0.208) |
0.0976 (0.178) |
0.0325 (0.0783) |
0.482 (0.577) |
0.537 (0.619) |
0.0539 (0.116) |
0.0208 (0.0566) |
0.0297 (0.0738) |
| del 16p13 3 | 174 (43%) | 234 |
1e-05 (9.73e-05) |
0.0186 (0.0518) |
0.00575 (0.0211) |
0.441 (0.543) |
0.00794 (0.0275) |
0.262 (0.373) |
0.946 (0.956) |
0.977 (0.98) |
0.411 (0.515) |
0.512 (0.595) |
| del 19p13 3 | 145 (36%) | 263 |
1e-05 (9.73e-05) |
0.488 (0.581) |
0.265 (0.375) |
0.155 (0.258) |
0.0203 (0.0552) |
0.00089 (0.00474) |
0.0385 (0.0896) |
0.11 (0.194) |
0.352 (0.461) |
0.102 (0.183) |
| amp 1p34 2 | 101 (25%) | 307 |
1e-05 (9.73e-05) |
0.00741 (0.0261) |
0.287 (0.396) |
0.652 (0.719) |
0.184 (0.291) |
0.0981 (0.178) |
0.065 (0.134) |
0.0237 (0.062) |
0.283 (0.393) |
0.0958 (0.176) |
| amp 4q13 3 | 62 (15%) | 346 |
1e-05 (9.73e-05) |
0.0299 (0.0738) |
0.281 (0.391) |
0.66 (0.725) |
0.393 (0.496) |
0.447 (0.546) |
0.085 (0.162) |
0.0918 (0.17) |
0.118 (0.206) |
0.00162 (0.00748) |
| amp 6q23 3 | 46 (11%) | 362 |
0.00518 (0.0193) |
0.624 (0.697) |
0.467 (0.565) |
0.224 (0.334) |
0.011 (0.0342) |
0.829 (0.873) |
0.205 (0.318) |
0.0299 (0.0738) |
0.178 (0.284) |
0.161 (0.263) |
| amp 7p11 2 | 190 (47%) | 218 |
1e-05 (9.73e-05) |
0.00844 (0.0285) |
0.00173 (0.00789) |
0.218 (0.33) |
0.0613 (0.128) |
0.256 (0.365) |
0.0881 (0.166) |
0.645 (0.713) |
0.0737 (0.147) |
0.0895 (0.168) |
| amp 8p11 21 | 140 (34%) | 268 |
1e-05 (9.73e-05) |
0.00071 (0.00396) |
0.0873 (0.165) |
0.611 (0.684) |
0.285 (0.394) |
0.313 (0.423) |
0.773 (0.829) |
0.0367 (0.0861) |
0.555 (0.632) |
0.482 (0.577) |
| amp 16p13 2 | 87 (21%) | 321 |
1e-05 (9.73e-05) |
0.00044 (0.00265) |
0.986 (0.987) |
0.782 (0.837) |
0.00818 (0.0279) |
0.0849 (0.162) |
0.206 (0.318) |
0.284 (0.394) |
0.507 (0.593) |
0.408 (0.512) |
| amp 19q12 | 164 (40%) | 244 |
1e-05 (9.73e-05) |
0.00235 (0.0102) |
0.236 (0.344) |
0.796 (0.847) |
0.23 (0.34) |
0.115 (0.203) |
0.156 (0.258) |
0.0427 (0.0968) |
0.247 (0.355) |
0.176 (0.281) |
| amp 19q13 43 | 155 (38%) | 253 |
1e-05 (9.73e-05) |
0.00636 (0.0229) |
0.0897 (0.168) |
0.652 (0.719) |
0.344 (0.453) |
0.547 (0.625) |
0.103 (0.185) |
0.296 (0.407) |
0.0472 (0.105) |
0.083 (0.16) |
| amp 20q11 21 | 263 (64%) | 145 |
1e-05 (9.73e-05) |
0.0692 (0.139) |
0.141 (0.241) |
0.508 (0.594) |
0.23 (0.34) |
0.0267 (0.0685) |
0.211 (0.324) |
0.156 (0.258) |
0.0661 (0.135) |
0.0469 (0.105) |
| del 1q32 1 | 72 (18%) | 336 |
0.00028 (0.00186) |
0.0279 (0.0708) |
0.597 (0.671) |
0.195 (0.306) |
0.459 (0.559) |
0.0447 (0.101) |
0.431 (0.533) |
0.734 (0.792) |
0.559 (0.635) |
0.641 (0.71) |
| del 2q22 1 | 134 (33%) | 274 |
0.00127 (0.00614) |
0.0077 (0.0269) |
0.492 (0.583) |
0.976 (0.98) |
0.00036 (0.00223) |
0.16 (0.262) |
0.173 (0.278) |
0.382 (0.49) |
0.072 (0.144) |
0.698 (0.764) |
| del 16q23 1 | 119 (29%) | 289 |
1e-05 (9.73e-05) |
0.079 (0.153) |
0.077 (0.15) |
0.101 (0.182) |
0.00735 (0.026) |
0.0654 (0.134) |
0.00534 (0.0197) |
0.201 (0.312) |
0.0645 (0.133) |
0.0616 (0.128) |
| del 17p12 | 208 (51%) | 200 |
1e-05 (9.73e-05) |
0.00056 (0.00322) |
0.33 (0.439) |
0.39 (0.495) |
0.224 (0.334) |
0.016 (0.0461) |
0.759 (0.815) |
0.806 (0.856) |
0.234 (0.344) |
0.715 (0.777) |
| del xq21 33 | 84 (21%) | 324 |
0.234 (0.344) |
0.0416 (0.0952) |
0.328 (0.438) |
0.252 (0.362) |
0.0118 (0.0364) |
0.0966 (0.177) |
0.156 (0.258) |
0.0495 (0.109) |
0.0508 (0.111) |
0.181 (0.287) |
| amp 6q21 | 35 (9%) | 373 |
0.00069 (0.0039) |
0.0617 (0.128) |
0.221 (0.333) |
0.389 (0.495) |
0.00071 (0.00396) |
0.0585 (0.124) |
0.581 (0.655) |
0.898 (0.922) |
0.271 (0.381) |
0.711 (0.775) |
| amp 8p11 23 | 124 (30%) | 284 |
1e-05 (9.73e-05) |
0.0179 (0.0501) |
0.534 (0.615) |
0.344 (0.453) |
0.279 (0.389) |
0.213 (0.324) |
0.264 (0.375) |
0.476 (0.573) |
0.866 (0.898) |
0.849 (0.887) |
| amp 12p12 1 | 132 (32%) | 276 |
6e-05 (0.000487) |
0.0652 (0.134) |
0.0888 (0.167) |
0.869 (0.9) |
0.218 (0.33) |
0.63 (0.7) |
0.304 (0.414) |
0.421 (0.525) |
0.232 (0.343) |
0.0235 (0.062) |
| amp 16p11 2 | 98 (24%) | 310 |
1e-05 (9.73e-05) |
0.019 (0.0524) |
0.724 (0.784) |
0.512 (0.595) |
0.429 (0.532) |
0.39 (0.495) |
0.545 (0.624) |
0.378 (0.487) |
0.938 (0.951) |
0.83 (0.873) |
| amp 17q23 3 | 194 (48%) | 214 |
1e-05 (9.73e-05) |
0.0321 (0.0778) |
0.117 (0.205) |
0.856 (0.892) |
0.429 (0.532) |
0.362 (0.47) |
0.435 (0.536) |
0.286 (0.395) |
0.131 (0.226) |
0.356 (0.465) |
| del 4q34 2 | 177 (43%) | 231 |
1e-05 (9.73e-05) |
0.0582 (0.124) |
0.0668 (0.136) |
0.076 (0.15) |
0.143 (0.244) |
0.041 (0.094) |
0.169 (0.274) |
0.63 (0.7) |
0.499 (0.588) |
0.12 (0.208) |
| del 10p11 21 | 74 (18%) | 334 |
0.012 (0.0366) |
0.916 (0.937) |
0.152 (0.256) |
0.512 (0.595) |
0.0308 (0.0751) |
0.0685 (0.139) |
0.499 (0.588) |
0.502 (0.589) |
0.218 (0.33) |
0.0847 (0.162) |
| del 10q23 31 | 168 (41%) | 240 |
1e-05 (9.73e-05) |
0.0275 (0.0701) |
0.132 (0.228) |
0.0744 (0.148) |
0.179 (0.284) |
0.567 (0.643) |
0.806 (0.856) |
0.492 (0.583) |
0.244 (0.353) |
0.727 (0.785) |
| del 12q24 33 | 88 (22%) | 320 |
1e-05 (9.73e-05) |
0.495 (0.585) |
0.299 (0.408) |
0.334 (0.443) |
0.0218 (0.0582) |
0.385 (0.493) |
0.788 (0.841) |
0.517 (0.599) |
0.94 (0.952) |
0.964 (0.971) |
| amp 11q13 3 | 135 (33%) | 273 |
3e-05 (0.000264) |
0.133 (0.229) |
0.816 (0.864) |
0.0854 (0.162) |
0.0573 (0.123) |
0.325 (0.436) |
0.109 (0.193) |
0.434 (0.536) |
0.197 (0.309) |
0.118 (0.206) |
| amp 13q22 1 | 128 (31%) | 280 |
1e-05 (9.73e-05) |
0.933 (0.949) |
0.319 (0.43) |
0.821 (0.867) |
0.97 (0.975) |
0.371 (0.48) |
0.377 (0.487) |
0.727 (0.785) |
0.863 (0.897) |
0.994 (0.994) |
| amp 17p11 2 | 88 (22%) | 320 |
0.00468 (0.0177) |
0.152 (0.256) |
0.654 (0.721) |
0.937 (0.951) |
0.233 (0.343) |
0.626 (0.698) |
0.388 (0.495) |
0.224 (0.334) |
0.31 (0.42) |
0.478 (0.574) |
| amp 22q12 2 | 87 (21%) | 321 |
8e-05 (0.000621) |
0.0533 (0.116) |
0.784 (0.838) |
0.752 (0.808) |
0.173 (0.278) |
0.0616 (0.128) |
0.098 (0.178) |
0.857 (0.892) |
0.442 (0.543) |
0.923 (0.944) |
| del 1p36 11 | 91 (22%) | 317 |
0.141 (0.241) |
0.016 (0.0461) |
0.0969 (0.177) |
0.326 (0.436) |
0.0759 (0.15) |
0.952 (0.96) |
0.363 (0.47) |
0.056 (0.12) |
0.456 (0.556) |
0.7 (0.765) |
| del 11q23 3 | 153 (38%) | 255 |
1e-05 (9.73e-05) |
0.297 (0.407) |
0.39 (0.495) |
0.71 (0.774) |
0.517 (0.599) |
0.2 (0.312) |
0.399 (0.502) |
0.0862 (0.163) |
0.412 (0.515) |
0.228 (0.339) |
| del 11q25 | 144 (35%) | 264 |
1e-05 (9.73e-05) |
0.243 (0.352) |
0.482 (0.577) |
0.424 (0.528) |
0.545 (0.624) |
0.246 (0.355) |
0.501 (0.589) |
0.0789 (0.153) |
0.299 (0.408) |
0.307 (0.418) |
| del xp11 3 | 91 (22%) | 317 |
0.437 (0.538) |
0.0763 (0.15) |
0.933 (0.949) |
0.85 (0.887) |
0.321 (0.431) |
0.572 (0.647) |
0.693 (0.759) |
0.148 (0.251) |
0.449 (0.548) |
0.318 (0.429) |
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S1. Gene #1: 'amp_1p34.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 1(1P34.2) MUTATED | 23 | 58 | 5 | 14 | 1 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 55 | 88 | 116 | 47 | 1 |
Figure S1. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00741 (Fisher's exact test), Q value = 0.026
Table S2. Gene #1: 'amp_1p34.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 1(1P34.2) MUTATED | 31 | 45 | 10 | 15 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 107 | 82 | 53 | 65 |
Figure S2. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0237 (Fisher's exact test), Q value = 0.062
Table S3. Gene #1: 'amp_1p34.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 1(1P34.2) MUTATED | 55 | 28 | 18 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 211 | 55 | 38 |
Figure S3. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S4. Gene #2: 'amp_1q21.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 2(1Q21.3) MUTATED | 50 | 95 | 21 | 34 | 2 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 28 | 51 | 100 | 27 | 0 |
Figure S4. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00589 (Fisher's exact test), Q value = 0.021
Table S5. Gene #2: 'amp_1q21.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 2(1Q21.3) MUTATED | 60 | 79 | 26 | 37 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 78 | 48 | 37 | 43 |
Figure S5. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0093 (Fisher's exact test), Q value = 0.03
Table S6. Gene #2: 'amp_1q21.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 2(1Q21.3) MUTATED | 34 | 65 | 15 | 47 | 40 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 38 | 70 | 23 | 56 | 16 |
Figure S6. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0133 (Fisher's exact test), Q value = 0.04
Table S7. Gene #2: 'amp_1q21.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 2(1Q21.3) MUTATED | 48 | 44 | 52 | 19 | 38 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 57 | 30 | 62 | 6 | 49 |
Figure S7. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0351 (Fisher's exact test), Q value = 0.083
Table S8. Gene #2: 'amp_1q21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 2(1Q21.3) MUTATED | 36 | 32 | 27 | 71 | 30 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 51 | 28 | 14 | 61 | 44 |
Figure S8. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S9. Gene #3: 'amp_1q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 3(1Q23.3) MUTATED | 52 | 105 | 26 | 31 | 2 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 26 | 41 | 95 | 30 | 0 |
Figure S9. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0409 (Fisher's exact test), Q value = 0.094
Table S10. Gene #3: 'amp_1q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 3(1Q23.3) MUTATED | 70 | 80 | 28 | 38 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 68 | 47 | 35 | 42 |
Figure S10. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0285 (Fisher's exact test), Q value = 0.072
Table S11. Gene #3: 'amp_1q23.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 3(1Q23.3) MUTATED | 36 | 73 | 16 | 50 | 40 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 36 | 62 | 22 | 53 | 16 |
Figure S11. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0252 (Fisher's exact test), Q value = 0.065
Table S12. Gene #3: 'amp_1q23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 3(1Q23.3) MUTATED | 75 | 53 | 87 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 43 | 59 | 87 |
Figure S12. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00156 (Fisher's exact test), Q value = 0.0073
Table S13. Gene #3: 'amp_1q23.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 3(1Q23.3) MUTATED | 49 | 54 | 55 | 16 | 41 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 56 | 20 | 59 | 9 | 46 |
Figure S13. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 8e-04 (Fisher's exact test), Q value = 0.0044
Table S14. Gene #3: 'amp_1q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 3(1Q23.3) MUTATED | 127 | 59 | 29 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 139 | 24 | 27 |
Figure S14. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0447 (Fisher's exact test), Q value = 0.1
Table S15. Gene #3: 'amp_1q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 3(1Q23.3) MUTATED | 66 | 36 | 65 | 43 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 58 | 15 | 62 | 49 |
Figure S15. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0108 (Fisher's exact test), Q value = 0.034
Table S16. Gene #3: 'amp_1q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 3(1Q23.3) MUTATED | 40 | 41 | 26 | 72 | 31 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 47 | 19 | 15 | 60 | 43 |
Figure S16. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S17. Gene #4: 'amp_2p25.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 4(2P25.1) MUTATED | 36 | 80 | 16 | 19 | 1 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 42 | 66 | 105 | 42 | 1 |
Figure S17. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S18. Gene #4: 'amp_2p25.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 4(2P25.1) MUTATED | 41 | 73 | 15 | 23 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 97 | 54 | 48 | 57 |
Figure S18. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0021
Table S19. Gene #4: 'amp_2p25.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 4(2P25.1) MUTATED | 25 | 62 | 5 | 31 | 28 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 47 | 73 | 33 | 72 | 28 |
Figure S19. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S20. Gene #4: 'amp_2p25.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 4(2P25.1) MUTATED | 64 | 38 | 49 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 54 | 74 | 125 |
Figure S20. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00521 (Fisher's exact test), Q value = 0.019
Table S21. Gene #4: 'amp_2p25.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 4(2P25.1) MUTATED | 29 | 39 | 40 | 13 | 29 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 76 | 35 | 74 | 12 | 58 |
Figure S21. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00802 (Fisher's exact test), Q value = 0.028
Table S22. Gene #4: 'amp_2p25.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 4(2P25.1) MUTATED | 88 | 43 | 19 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 178 | 40 | 37 |
Figure S22. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0379 (Fisher's exact test), Q value = 0.088
Table S23. Gene #4: 'amp_2p25.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 4(2P25.1) MUTATED | 47 | 27 | 48 | 26 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 77 | 24 | 79 | 66 |
Figure S23. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00054 (Fisher's exact test), Q value = 0.0031
Table S24. Gene #4: 'amp_2p25.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 4(2P25.1) MUTATED | 28 | 32 | 20 | 53 | 15 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 59 | 28 | 21 | 79 | 59 |
Figure S24. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S25. Gene #5: 'amp_3p25.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 5(3P25.2) MUTATED | 52 | 92 | 19 | 26 | 1 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 26 | 54 | 102 | 35 | 1 |
Figure S25. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S26. Gene #5: 'amp_3p25.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 5(3P25.2) MUTATED | 48 | 87 | 27 | 28 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 90 | 40 | 36 | 52 |
Figure S26. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0265 (Fisher's exact test), Q value = 0.068
Table S27. Gene #5: 'amp_3p25.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| AMP PEAK 5(3P25.2) MUTATED | 42 | 65 | 35 | 10 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 48 | 56 | 63 | 21 |
Figure S27. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S28. Gene #5: 'amp_3p25.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 5(3P25.2) MUTATED | 35 | 84 | 4 | 32 | 33 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 37 | 51 | 34 | 71 | 23 |
Figure S28. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S29. Gene #5: 'amp_3p25.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 5(3P25.2) MUTATED | 78 | 60 | 50 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 40 | 52 | 124 |
Figure S29. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 9e-04
Table S30. Gene #5: 'amp_3p25.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 5(3P25.2) MUTATED | 36 | 51 | 53 | 13 | 36 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 69 | 23 | 61 | 12 | 51 |
Figure S30. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 9e-04
Table S31. Gene #5: 'amp_3p25.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 5(3P25.2) MUTATED | 105 | 55 | 29 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 161 | 28 | 27 |
Figure S31. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S32. Gene #5: 'amp_3p25.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 5(3P25.2) MUTATED | 55 | 40 | 62 | 28 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 69 | 11 | 65 | 64 |
Figure S32. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S33. Gene #5: 'amp_3p25.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 5(3P25.2) MUTATED | 39 | 43 | 15 | 68 | 20 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 48 | 17 | 26 | 64 | 54 |
Figure S33. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S34. Gene #6: 'amp_3q26.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 6(3Q26.33) MUTATED | 54 | 99 | 33 | 30 | 2 |
| AMP PEAK 6(3Q26.33) WILD-TYPE | 24 | 47 | 88 | 31 | 0 |
Figure S34. Get High-res Image Gene #6: 'amp_3q26.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0018 (Fisher's exact test), Q value = 0.0081
Table S35. Gene #6: 'amp_3q26.33' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 6(3Q26.33) MUTATED | 59 | 48 | 68 |
| AMP PEAK 6(3Q26.33) WILD-TYPE | 63 | 66 | 36 |
Figure S35. Get High-res Image Gene #6: 'amp_3q26.33' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0226 (Fisher's exact test), Q value = 0.06
Table S36. Gene #6: 'amp_3q26.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 6(3Q26.33) MUTATED | 74 | 50 | 93 |
| AMP PEAK 6(3Q26.33) WILD-TYPE | 44 | 62 | 81 |
Figure S36. Get High-res Image Gene #6: 'amp_3q26.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.033
Table S37. Gene #6: 'amp_3q26.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 6(3Q26.33) MUTATED | 58 | 49 | 48 | 17 | 44 |
| AMP PEAK 6(3Q26.33) WILD-TYPE | 47 | 25 | 66 | 8 | 43 |
Figure S37. Get High-res Image Gene #6: 'amp_3q26.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0283 (Fisher's exact test), Q value = 0.071
Table S38. Gene #7: 'amp_4p16.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 7(4P16.3) MUTATED | 18 | 35 | 15 | 6 | 0 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 60 | 111 | 106 | 55 | 2 |
Figure S38. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.03 (Fisher's exact test), Q value = 0.074
Table S39. Gene #7: 'amp_4p16.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 7(4P16.3) MUTATED | 15 | 30 | 11 | 18 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 123 | 97 | 52 | 62 |
Figure S39. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00373 (Fisher's exact test), Q value = 0.015
Table S40. Gene #7: 'amp_4p16.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 7(4P16.3) MUTATED | 12 | 29 | 23 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 110 | 85 | 81 |
Figure S40. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.0014
Table S41. Gene #7: 'amp_4p16.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| AMP PEAK 7(4P16.3) MUTATED | 13 | 38 | 10 | 3 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 77 | 83 | 88 | 28 |
Figure S41. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0179 (Fisher's exact test), Q value = 0.05
Table S42. Gene #7: 'amp_4p16.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 7(4P16.3) MUTATED | 7 | 33 | 11 | 14 | 8 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 65 | 102 | 27 | 89 | 48 |
Figure S42. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00049
Table S43. Gene #7: 'amp_4p16.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 7(4P16.3) MUTATED | 20 | 35 | 18 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 98 | 77 | 156 |
Figure S43. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00026 (Fisher's exact test), Q value = 0.0018
Table S44. Gene #7: 'amp_4p16.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 7(4P16.3) MUTATED | 15 | 21 | 30 | 2 | 6 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 90 | 53 | 84 | 23 | 81 |
Figure S44. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00124 (Fisher's exact test), Q value = 0.0061
Table S45. Gene #7: 'amp_4p16.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 7(4P16.3) MUTATED | 47 | 24 | 3 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 219 | 59 | 53 |
Figure S45. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0217 (Fisher's exact test), Q value = 0.058
Table S46. Gene #7: 'amp_4p16.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 7(4P16.3) MUTATED | 15 | 11 | 33 | 13 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 109 | 40 | 94 | 79 |
Figure S46. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00202 (Fisher's exact test), Q value = 0.0089
Table S47. Gene #7: 'amp_4p16.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 7(4P16.3) MUTATED | 7 | 15 | 4 | 35 | 11 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 80 | 45 | 37 | 97 | 63 |
Figure S47. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S48. Gene #8: 'amp_4q13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 8(4Q13.3) MUTATED | 12 | 41 | 5 | 4 | 0 |
| AMP PEAK 8(4Q13.3) WILD-TYPE | 66 | 105 | 116 | 57 | 2 |
Figure S48. Get High-res Image Gene #8: 'amp_4q13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0299 (Fisher's exact test), Q value = 0.074
Table S49. Gene #8: 'amp_4q13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 8(4Q13.3) MUTATED | 18 | 28 | 4 | 12 |
| AMP PEAK 8(4Q13.3) WILD-TYPE | 120 | 99 | 59 | 68 |
Figure S49. Get High-res Image Gene #8: 'amp_4q13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00162 (Fisher's exact test), Q value = 0.0075
Table S50. Gene #8: 'amp_4q13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 8(4Q13.3) MUTATED | 5 | 14 | 8 | 28 | 6 |
| AMP PEAK 8(4Q13.3) WILD-TYPE | 82 | 46 | 33 | 104 | 68 |
Figure S50. Get High-res Image Gene #8: 'amp_4q13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S51. Gene #9: 'amp_5p15.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 9(5P15.33) MUTATED | 50 | 94 | 20 | 40 | 2 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 28 | 52 | 101 | 21 | 0 |
Figure S51. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00054 (Fisher's exact test), Q value = 0.0031
Table S52. Gene #9: 'amp_5p15.33' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 9(5P15.33) MUTATED | 63 | 40 | 63 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 59 | 74 | 41 |
Figure S52. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.014 (Fisher's exact test), Q value = 0.042
Table S53. Gene #9: 'amp_5p15.33' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| AMP PEAK 9(5P15.33) MUTATED | 41 | 48 | 58 | 19 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 49 | 73 | 40 | 12 |
Figure S53. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00815 (Fisher's exact test), Q value = 0.028
Table S54. Gene #9: 'amp_5p15.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 9(5P15.33) MUTATED | 32 | 61 | 13 | 63 | 34 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 40 | 74 | 25 | 40 | 22 |
Figure S54. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0195 (Fisher's exact test), Q value = 0.054
Table S55. Gene #9: 'amp_5p15.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 9(5P15.33) MUTATED | 50 | 52 | 101 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 68 | 60 | 73 |
Figure S55. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00472 (Fisher's exact test), Q value = 0.018
Table S56. Gene #9: 'amp_5p15.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 9(5P15.33) MUTATED | 54 | 47 | 42 | 15 | 47 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 51 | 27 | 72 | 10 | 40 |
Figure S56. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0167 (Fisher's exact test), Q value = 0.047
Table S57. Gene #9: 'amp_5p15.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 9(5P15.33) MUTATED | 121 | 51 | 33 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 145 | 32 | 23 |
Figure S57. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00463 (Fisher's exact test), Q value = 0.018
Table S58. Gene #9: 'amp_5p15.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 9(5P15.33) MUTATED | 35 | 35 | 28 | 59 | 45 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 52 | 25 | 13 | 73 | 29 |
Figure S58. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S59. Gene #10: 'amp_6p22.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 10(6P22.3) MUTATED | 37 | 82 | 10 | 41 | 1 |
| AMP PEAK 10(6P22.3) WILD-TYPE | 41 | 64 | 111 | 20 | 1 |
Figure S59. Get High-res Image Gene #10: 'amp_6p22.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00042
Table S60. Gene #10: 'amp_6p22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 10(6P22.3) MUTATED | 56 | 73 | 18 | 24 |
| AMP PEAK 10(6P22.3) WILD-TYPE | 82 | 54 | 45 | 56 |
Figure S60. Get High-res Image Gene #10: 'amp_6p22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0459 (Fisher's exact test), Q value = 0.1
Table S61. Gene #10: 'amp_6p22.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 10(6P22.3) MUTATED | 41 | 41 | 51 |
| AMP PEAK 10(6P22.3) WILD-TYPE | 81 | 73 | 53 |
Figure S61. Get High-res Image Gene #10: 'amp_6p22.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00158 (Fisher's exact test), Q value = 0.0074
Table S62. Gene #10: 'amp_6p22.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 10(6P22.3) MUTATED | 21 | 60 | 8 | 48 | 31 |
| AMP PEAK 10(6P22.3) WILD-TYPE | 51 | 75 | 30 | 55 | 25 |
Figure S62. Get High-res Image Gene #10: 'amp_6p22.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0039
Table S63. Gene #11: 'amp_6q21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 11(6Q21) MUTATED | 5 | 15 | 4 | 9 | 2 |
| AMP PEAK 11(6Q21) WILD-TYPE | 73 | 131 | 117 | 52 | 0 |
Figure S63. Get High-res Image Gene #11: 'amp_6q21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00071 (Fisher's exact test), Q value = 0.004
Table S64. Gene #11: 'amp_6q21' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 11(6Q21) MUTATED | 4 | 10 | 2 | 4 | 14 |
| AMP PEAK 11(6Q21) WILD-TYPE | 68 | 125 | 36 | 99 | 42 |
Figure S64. Get High-res Image Gene #11: 'amp_6q21' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00518 (Fisher's exact test), Q value = 0.019
Table S65. Gene #12: 'amp_6q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 12(6Q23.3) MUTATED | 6 | 21 | 8 | 9 | 2 |
| AMP PEAK 12(6Q23.3) WILD-TYPE | 72 | 125 | 113 | 52 | 0 |
Figure S65. Get High-res Image Gene #12: 'amp_6q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.011 (Fisher's exact test), Q value = 0.034
Table S66. Gene #12: 'amp_6q23.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 12(6Q23.3) MUTATED | 4 | 16 | 3 | 8 | 14 |
| AMP PEAK 12(6Q23.3) WILD-TYPE | 68 | 119 | 35 | 95 | 42 |
Figure S66. Get High-res Image Gene #12: 'amp_6q23.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0299 (Fisher's exact test), Q value = 0.074
Table S67. Gene #12: 'amp_6q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 12(6Q23.3) MUTATED | 34 | 11 | 1 |
| AMP PEAK 12(6Q23.3) WILD-TYPE | 232 | 72 | 55 |
Figure S67. Get High-res Image Gene #12: 'amp_6q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S68. Gene #13: 'amp_7p21.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 13(7P21.1) MUTATED | 51 | 91 | 17 | 40 | 2 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 27 | 55 | 104 | 21 | 0 |
Figure S68. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00359 (Fisher's exact test), Q value = 0.015
Table S69. Gene #13: 'amp_7p21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 13(7P21.1) MUTATED | 69 | 77 | 23 | 32 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 69 | 50 | 40 | 48 |
Figure S69. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0218 (Fisher's exact test), Q value = 0.058
Table S70. Gene #13: 'amp_7p21.1' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 13(7P21.1) MUTATED | 55 | 48 | 62 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 67 | 66 | 42 |
Figure S70. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0133 (Fisher's exact test), Q value = 0.04
Table S71. Gene #13: 'amp_7p21.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 13(7P21.1) MUTATED | 29 | 65 | 12 | 60 | 33 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 43 | 70 | 26 | 43 | 23 |
Figure S71. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0231 (Fisher's exact test), Q value = 0.061
Table S72. Gene #13: 'amp_7p21.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 13(7P21.1) MUTATED | 65 | 43 | 91 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 53 | 69 | 83 |
Figure S72. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S73. Gene #14: 'amp_7p11.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 14(7P11.2) MUTATED | 56 | 80 | 16 | 36 | 2 |
| AMP PEAK 14(7P11.2) WILD-TYPE | 22 | 66 | 105 | 25 | 0 |
Figure S73. Get High-res Image Gene #14: 'amp_7p11.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00844 (Fisher's exact test), Q value = 0.029
Table S74. Gene #14: 'amp_7p11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 14(7P11.2) MUTATED | 67 | 71 | 20 | 32 |
| AMP PEAK 14(7P11.2) WILD-TYPE | 71 | 56 | 43 | 48 |
Figure S74. Get High-res Image Gene #14: 'amp_7p11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00173 (Fisher's exact test), Q value = 0.0079
Table S75. Gene #14: 'amp_7p11.2' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 14(7P11.2) MUTATED | 51 | 43 | 63 |
| AMP PEAK 14(7P11.2) WILD-TYPE | 71 | 71 | 41 |
Figure S75. Get High-res Image Gene #14: 'amp_7p11.2' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S76. Gene #15: 'amp_8p11.23' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 15(8P11.23) MUTATED | 62 | 30 | 20 | 10 | 2 |
| AMP PEAK 15(8P11.23) WILD-TYPE | 16 | 116 | 101 | 51 | 0 |
Figure S76. Get High-res Image Gene #15: 'amp_8p11.23' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0179 (Fisher's exact test), Q value = 0.05
Table S77. Gene #15: 'amp_8p11.23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 15(8P11.23) MUTATED | 36 | 43 | 12 | 33 |
| AMP PEAK 15(8P11.23) WILD-TYPE | 102 | 84 | 51 | 47 |
Figure S77. Get High-res Image Gene #15: 'amp_8p11.23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S78. Gene #16: 'amp_8p11.21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 16(8P11.21) MUTATED | 64 | 41 | 18 | 16 | 1 |
| AMP PEAK 16(8P11.21) WILD-TYPE | 14 | 105 | 103 | 45 | 1 |
Figure S78. Get High-res Image Gene #16: 'amp_8p11.21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00071 (Fisher's exact test), Q value = 0.004
Table S79. Gene #16: 'amp_8p11.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 16(8P11.21) MUTATED | 40 | 56 | 11 | 33 |
| AMP PEAK 16(8P11.21) WILD-TYPE | 98 | 71 | 52 | 47 |
Figure S79. Get High-res Image Gene #16: 'amp_8p11.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0367 (Fisher's exact test), Q value = 0.086
Table S80. Gene #16: 'amp_8p11.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 16(8P11.21) MUTATED | 99 | 29 | 11 |
| AMP PEAK 16(8P11.21) WILD-TYPE | 167 | 54 | 45 |
Figure S80. Get High-res Image Gene #16: 'amp_8p11.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S81. Gene #17: 'amp_8q22.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 17(8Q22.3) MUTATED | 68 | 111 | 45 | 39 | 1 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 10 | 35 | 76 | 22 | 1 |
Figure S81. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00062
Table S82. Gene #17: 'amp_8q22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 17(8Q22.3) MUTATED | 82 | 101 | 30 | 51 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 56 | 26 | 33 | 29 |
Figure S82. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0124 (Fisher's exact test), Q value = 0.037
Table S83. Gene #17: 'amp_8q22.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 17(8Q22.3) MUTATED | 75 | 66 | 79 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 47 | 48 | 25 |
Figure S83. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0337 (Fisher's exact test), Q value = 0.08
Table S84. Gene #17: 'amp_8q22.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 17(8Q22.3) MUTATED | 170 | 62 | 30 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 96 | 21 | 26 |
Figure S84. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0327 (Fisher's exact test), Q value = 0.078
Table S85. Gene #17: 'amp_8q22.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 17(8Q22.3) MUTATED | 75 | 42 | 83 | 57 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 49 | 9 | 44 | 35 |
Figure S85. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S86. Gene #18: 'amp_8q24.21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 18(8Q24.21) MUTATED | 65 | 107 | 43 | 37 | 2 |
| AMP PEAK 18(8Q24.21) WILD-TYPE | 13 | 39 | 78 | 24 | 0 |
Figure S86. Get High-res Image Gene #18: 'amp_8q24.21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00125 (Fisher's exact test), Q value = 0.0061
Table S87. Gene #18: 'amp_8q24.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 18(8Q24.21) MUTATED | 82 | 93 | 28 | 51 |
| AMP PEAK 18(8Q24.21) WILD-TYPE | 56 | 34 | 35 | 29 |
Figure S87. Get High-res Image Gene #18: 'amp_8q24.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0021
Table S88. Gene #18: 'amp_8q24.21' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 18(8Q24.21) MUTATED | 71 | 59 | 80 |
| AMP PEAK 18(8Q24.21) WILD-TYPE | 51 | 55 | 24 |
Figure S88. Get High-res Image Gene #18: 'amp_8q24.21' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0492 (Fisher's exact test), Q value = 0.11
Table S89. Gene #18: 'amp_8q24.21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 18(8Q24.21) MUTATED | 70 | 53 | 66 | 18 | 45 |
| AMP PEAK 18(8Q24.21) WILD-TYPE | 35 | 21 | 48 | 7 | 42 |
Figure S89. Get High-res Image Gene #18: 'amp_8q24.21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0142 (Fisher's exact test), Q value = 0.042
Table S90. Gene #18: 'amp_8q24.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 18(8Q24.21) MUTATED | 167 | 59 | 26 |
| AMP PEAK 18(8Q24.21) WILD-TYPE | 99 | 24 | 30 |
Figure S90. Get High-res Image Gene #18: 'amp_8q24.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S91. Gene #19: 'amp_9p24.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 19(9P24.1) MUTATED | 23 | 20 | 10 | 34 | 1 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 55 | 126 | 111 | 27 | 1 |
Figure S91. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00406 (Fisher's exact test), Q value = 0.016
Table S92. Gene #19: 'amp_9p24.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 19(9P24.1) MUTATED | 44 | 21 | 8 | 15 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 94 | 106 | 55 | 65 |
Figure S92. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0309 (Fisher's exact test), Q value = 0.075
Table S93. Gene #19: 'amp_9p24.1' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 19(9P24.1) MUTATED | 34 | 16 | 24 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 88 | 98 | 80 |
Figure S93. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00909 (Fisher's exact test), Q value = 0.03
Table S94. Gene #19: 'amp_9p24.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| AMP PEAK 19(9P24.1) MUTATED | 19 | 16 | 28 | 11 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 71 | 105 | 70 | 20 |
Figure S94. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0237 (Fisher's exact test), Q value = 0.062
Table S95. Gene #19: 'amp_9p24.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 19(9P24.1) MUTATED | 14 | 24 | 3 | 32 | 13 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 58 | 111 | 35 | 71 | 43 |
Figure S95. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00167 (Fisher's exact test), Q value = 0.0077
Table S96. Gene #19: 'amp_9p24.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 19(9P24.1) MUTATED | 21 | 14 | 51 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 97 | 98 | 123 |
Figure S96. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00792 (Fisher's exact test), Q value = 0.027
Table S97. Gene #19: 'amp_9p24.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 19(9P24.1) MUTATED | 36 | 12 | 17 | 6 | 17 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 69 | 62 | 97 | 19 | 70 |
Figure S97. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.0011
Table S98. Gene #19: 'amp_9p24.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 19(9P24.1) MUTATED | 22 | 9 | 18 | 36 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 102 | 42 | 109 | 56 |
Figure S98. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00098 (Fisher's exact test), Q value = 0.005
Table S99. Gene #19: 'amp_9p24.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 19(9P24.1) MUTATED | 18 | 10 | 6 | 21 | 30 |
| AMP PEAK 19(9P24.1) WILD-TYPE | 69 | 50 | 35 | 111 | 44 |
Figure S99. Get High-res Image Gene #19: 'amp_9p24.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S100. Gene #20: 'amp_10p14' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 20(10P14) MUTATED | 45 | 89 | 12 | 36 | 0 |
| AMP PEAK 20(10P14) WILD-TYPE | 33 | 57 | 109 | 25 | 2 |
Figure S100. Get High-res Image Gene #20: 'amp_10p14' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S101. Gene #20: 'amp_10p14' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 20(10P14) MUTATED | 55 | 81 | 22 | 24 |
| AMP PEAK 20(10P14) WILD-TYPE | 83 | 46 | 41 | 56 |
Figure S101. Get High-res Image Gene #20: 'amp_10p14' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00451 (Fisher's exact test), Q value = 0.018
Table S102. Gene #20: 'amp_10p14' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 20(10P14) MUTATED | 33 | 63 | 7 | 45 | 32 |
| AMP PEAK 20(10P14) WILD-TYPE | 39 | 72 | 31 | 58 | 24 |
Figure S102. Get High-res Image Gene #20: 'amp_10p14' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00042
Table S103. Gene #20: 'amp_10p14' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 20(10P14) MUTATED | 73 | 39 | 68 |
| AMP PEAK 20(10P14) WILD-TYPE | 45 | 73 | 106 |
Figure S103. Get High-res Image Gene #20: 'amp_10p14' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S104. Gene #21: 'amp_11p13' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 21(11P13) MUTATED | 12 | 15 | 3 | 20 | 1 |
| AMP PEAK 21(11P13) WILD-TYPE | 66 | 131 | 118 | 41 | 1 |
Figure S104. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00361 (Fisher's exact test), Q value = 0.015
Table S105. Gene #21: 'amp_11p13' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 21(11P13) MUTATED | 25 | 19 | 4 | 3 |
| AMP PEAK 21(11P13) WILD-TYPE | 113 | 108 | 59 | 77 |
Figure S105. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00147 (Fisher's exact test), Q value = 0.007
Table S106. Gene #21: 'amp_11p13' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| AMP PEAK 21(11P13) MUTATED | 22 | 5 | 18 |
| AMP PEAK 21(11P13) WILD-TYPE | 100 | 109 | 86 |
Figure S106. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0363 (Fisher's exact test), Q value = 0.085
Table S107. Gene #21: 'amp_11p13' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| AMP PEAK 21(11P13) MUTATED | 14 | 8 | 17 | 6 |
| AMP PEAK 21(11P13) WILD-TYPE | 76 | 113 | 81 | 25 |
Figure S107. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.025 (Fisher's exact test), Q value = 0.065
Table S108. Gene #21: 'amp_11p13' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 21(11P13) MUTATED | 9 | 9 | 3 | 20 | 10 |
| AMP PEAK 21(11P13) WILD-TYPE | 63 | 126 | 35 | 83 | 46 |
Figure S108. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00084 (Fisher's exact test), Q value = 0.0045
Table S109. Gene #21: 'amp_11p13' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 21(11P13) MUTATED | 16 | 4 | 31 |
| AMP PEAK 21(11P13) WILD-TYPE | 102 | 108 | 143 |
Figure S109. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00079 (Fisher's exact test), Q value = 0.0043
Table S110. Gene #21: 'amp_11p13' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 21(11P13) MUTATED | 19 | 7 | 5 | 8 | 12 |
| AMP PEAK 21(11P13) WILD-TYPE | 86 | 67 | 109 | 17 | 75 |
Figure S110. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0308 (Fisher's exact test), Q value = 0.075
Table S111. Gene #21: 'amp_11p13' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 21(11P13) MUTATED | 16 | 4 | 11 | 20 |
| AMP PEAK 21(11P13) WILD-TYPE | 108 | 47 | 116 | 72 |
Figure S111. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.002
Table S112. Gene #21: 'amp_11p13' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 21(11P13) MUTATED | 10 | 4 | 7 | 9 | 21 |
| AMP PEAK 21(11P13) WILD-TYPE | 77 | 56 | 34 | 123 | 53 |
Figure S112. Get High-res Image Gene #21: 'amp_11p13' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00026
Table S113. Gene #22: 'amp_11q13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 22(11Q13.3) MUTATED | 33 | 62 | 21 | 18 | 1 |
| AMP PEAK 22(11Q13.3) WILD-TYPE | 45 | 84 | 100 | 43 | 1 |
Figure S113. Get High-res Image Gene #22: 'amp_11q13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S114. Gene #23: 'amp_11q22.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 23(11Q22.2) MUTATED | 20 | 33 | 4 | 14 | 0 |
| AMP PEAK 23(11Q22.2) WILD-TYPE | 58 | 113 | 117 | 47 | 2 |
Figure S114. Get High-res Image Gene #23: 'amp_11q22.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00091 (Fisher's exact test), Q value = 0.0048
Table S115. Gene #23: 'amp_11q22.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 23(11Q22.2) MUTATED | 25 | 22 | 11 | 4 | 9 |
| AMP PEAK 23(11Q22.2) WILD-TYPE | 80 | 52 | 103 | 21 | 78 |
Figure S115. Get High-res Image Gene #23: 'amp_11q22.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0199 (Fisher's exact test), Q value = 0.054
Table S116. Gene #23: 'amp_11q22.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 23(11Q22.2) MUTATED | 42 | 23 | 6 |
| AMP PEAK 23(11Q22.2) WILD-TYPE | 224 | 60 | 50 |
Figure S116. Get High-res Image Gene #23: 'amp_11q22.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00026 (Fisher's exact test), Q value = 0.0018
Table S117. Gene #23: 'amp_11q22.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 23(11Q22.2) MUTATED | 18 | 17 | 12 | 24 |
| AMP PEAK 23(11Q22.2) WILD-TYPE | 106 | 34 | 115 | 68 |
Figure S117. Get High-res Image Gene #23: 'amp_11q22.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0141 (Fisher's exact test), Q value = 0.042
Table S118. Gene #23: 'amp_11q22.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 23(11Q22.2) MUTATED | 10 | 17 | 5 | 19 | 20 |
| AMP PEAK 23(11Q22.2) WILD-TYPE | 77 | 43 | 36 | 113 | 54 |
Figure S118. Get High-res Image Gene #23: 'amp_11q22.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00049
Table S119. Gene #24: 'amp_12p12.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 24(12P12.1) MUTATED | 38 | 52 | 21 | 21 | 0 |
| AMP PEAK 24(12P12.1) WILD-TYPE | 40 | 94 | 100 | 40 | 2 |
Figure S119. Get High-res Image Gene #24: 'amp_12p12.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0235 (Fisher's exact test), Q value = 0.062
Table S120. Gene #24: 'amp_12p12.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 24(12P12.1) MUTATED | 17 | 22 | 17 | 43 | 30 |
| AMP PEAK 24(12P12.1) WILD-TYPE | 70 | 38 | 24 | 89 | 44 |
Figure S120. Get High-res Image Gene #24: 'amp_12p12.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00056
Table S121. Gene #25: 'amp_12q15' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 25(12Q15) MUTATED | 27 | 58 | 25 | 8 | 0 |
| AMP PEAK 25(12Q15) WILD-TYPE | 51 | 88 | 96 | 53 | 2 |
Figure S121. Get High-res Image Gene #25: 'amp_12q15' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0255 (Fisher's exact test), Q value = 0.066
Table S122. Gene #25: 'amp_12q15' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 25(12Q15) MUTATED | 22 | 44 | 12 | 18 | 22 |
| AMP PEAK 25(12Q15) WILD-TYPE | 50 | 91 | 26 | 85 | 34 |
Figure S122. Get High-res Image Gene #25: 'amp_12q15' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0091 (Fisher's exact test), Q value = 0.03
Table S123. Gene #25: 'amp_12q15' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 25(12Q15) MUTATED | 41 | 40 | 37 |
| AMP PEAK 25(12Q15) WILD-TYPE | 77 | 72 | 137 |
Figure S123. Get High-res Image Gene #25: 'amp_12q15' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00397 (Fisher's exact test), Q value = 0.016
Table S124. Gene #25: 'amp_12q15' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 25(12Q15) MUTATED | 16 | 28 | 36 | 9 | 29 |
| AMP PEAK 25(12Q15) WILD-TYPE | 89 | 46 | 78 | 16 | 58 |
Figure S124. Get High-res Image Gene #25: 'amp_12q15' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0363 (Fisher's exact test), Q value = 0.085
Table S125. Gene #25: 'amp_12q15' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 25(12Q15) MUTATED | 67 | 33 | 18 |
| AMP PEAK 25(12Q15) WILD-TYPE | 199 | 50 | 38 |
Figure S125. Get High-res Image Gene #25: 'amp_12q15' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0026 (Fisher's exact test), Q value = 0.011
Table S126. Gene #25: 'amp_12q15' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 25(12Q15) MUTATED | 43 | 20 | 40 | 14 |
| AMP PEAK 25(12Q15) WILD-TYPE | 81 | 31 | 87 | 78 |
Figure S126. Get High-res Image Gene #25: 'amp_12q15' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00062
Table S127. Gene #25: 'amp_12q15' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 25(12Q15) MUTATED | 23 | 28 | 19 | 37 | 10 |
| AMP PEAK 25(12Q15) WILD-TYPE | 64 | 32 | 22 | 95 | 64 |
Figure S127. Get High-res Image Gene #25: 'amp_12q15' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S128. Gene #26: 'amp_13q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 26(13Q22.1) MUTATED | 32 | 56 | 16 | 24 | 0 |
| AMP PEAK 26(13Q22.1) WILD-TYPE | 46 | 90 | 105 | 37 | 2 |
Figure S128. Get High-res Image Gene #26: 'amp_13q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S129. Gene #27: 'amp_16p13.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 27(16P13.2) MUTATED | 17 | 49 | 10 | 9 | 2 |
| AMP PEAK 27(16P13.2) WILD-TYPE | 61 | 97 | 111 | 52 | 0 |
Figure S129. Get High-res Image Gene #27: 'amp_16p13.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00044 (Fisher's exact test), Q value = 0.0027
Table S130. Gene #27: 'amp_16p13.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 27(16P13.2) MUTATED | 26 | 43 | 9 | 9 |
| AMP PEAK 27(16P13.2) WILD-TYPE | 112 | 84 | 54 | 71 |
Figure S130. Get High-res Image Gene #27: 'amp_16p13.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00818 (Fisher's exact test), Q value = 0.028
Table S131. Gene #27: 'amp_16p13.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 27(16P13.2) MUTATED | 12 | 28 | 6 | 18 | 23 |
| AMP PEAK 27(16P13.2) WILD-TYPE | 60 | 107 | 32 | 85 | 33 |
Figure S131. Get High-res Image Gene #27: 'amp_16p13.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S132. Gene #28: 'amp_16p11.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 28(16P11.2) MUTATED | 15 | 57 | 10 | 14 | 2 |
| AMP PEAK 28(16P11.2) WILD-TYPE | 63 | 89 | 111 | 47 | 0 |
Figure S132. Get High-res Image Gene #28: 'amp_16p11.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.019 (Fisher's exact test), Q value = 0.052
Table S133. Gene #28: 'amp_16p11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 28(16P11.2) MUTATED | 32 | 42 | 12 | 12 |
| AMP PEAK 28(16P11.2) WILD-TYPE | 106 | 85 | 51 | 68 |
Figure S133. Get High-res Image Gene #28: 'amp_16p11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S134. Gene #29: 'amp_16q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 29(16Q22.1) MUTATED | 13 | 72 | 11 | 11 | 1 |
| AMP PEAK 29(16Q22.1) WILD-TYPE | 65 | 74 | 110 | 50 | 1 |
Figure S134. Get High-res Image Gene #29: 'amp_16q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00466 (Fisher's exact test), Q value = 0.018
Table S135. Gene #29: 'amp_16q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 29(16Q22.1) MUTATED | 41 | 18 | 48 |
| AMP PEAK 29(16Q22.1) WILD-TYPE | 77 | 94 | 126 |
Figure S135. Get High-res Image Gene #29: 'amp_16q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0147 (Fisher's exact test), Q value = 0.043
Table S136. Gene #29: 'amp_16q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 29(16Q22.1) MUTATED | 59 | 31 | 18 |
| AMP PEAK 29(16Q22.1) WILD-TYPE | 207 | 52 | 38 |
Figure S136. Get High-res Image Gene #29: 'amp_16q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0292 (Fisher's exact test), Q value = 0.073
Table S137. Gene #29: 'amp_16q22.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 29(16Q22.1) MUTATED | 40 | 18 | 23 | 26 |
| AMP PEAK 29(16Q22.1) WILD-TYPE | 84 | 33 | 104 | 66 |
Figure S137. Get High-res Image Gene #29: 'amp_16q22.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00468 (Fisher's exact test), Q value = 0.018
Table S138. Gene #30: 'amp_17p11.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 30(17P11.2) MUTATED | 19 | 39 | 13 | 16 | 1 |
| AMP PEAK 30(17P11.2) WILD-TYPE | 59 | 107 | 108 | 45 | 1 |
Figure S138. Get High-res Image Gene #30: 'amp_17p11.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S139. Gene #31: 'amp_17q11.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 31(17Q11.2) MUTATED | 54 | 79 | 22 | 19 | 0 |
| AMP PEAK 31(17Q11.2) WILD-TYPE | 24 | 67 | 99 | 42 | 2 |
Figure S139. Get High-res Image Gene #31: 'amp_17q11.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S140. Gene #31: 'amp_17q11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 31(17Q11.2) MUTATED | 37 | 74 | 26 | 37 |
| AMP PEAK 31(17Q11.2) WILD-TYPE | 101 | 53 | 37 | 43 |
Figure S140. Get High-res Image Gene #31: 'amp_17q11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.0031
Table S141. Gene #31: 'amp_17q11.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| AMP PEAK 31(17Q11.2) MUTATED | 27 | 69 | 15 | 29 | 33 |
| AMP PEAK 31(17Q11.2) WILD-TYPE | 45 | 66 | 23 | 74 | 23 |
Figure S141. Get High-res Image Gene #31: 'amp_17q11.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.002
Table S142. Gene #31: 'amp_17q11.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 31(17Q11.2) MUTATED | 62 | 56 | 55 |
| AMP PEAK 31(17Q11.2) WILD-TYPE | 56 | 56 | 119 |
Figure S142. Get High-res Image Gene #31: 'amp_17q11.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00248 (Fisher's exact test), Q value = 0.011
Table S143. Gene #31: 'amp_17q11.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 31(17Q11.2) MUTATED | 53 | 29 | 62 | 26 |
| AMP PEAK 31(17Q11.2) WILD-TYPE | 71 | 22 | 65 | 66 |
Figure S143. Get High-res Image Gene #31: 'amp_17q11.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.01 (Fisher's exact test), Q value = 0.032
Table S144. Gene #31: 'amp_17q11.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 31(17Q11.2) MUTATED | 35 | 30 | 17 | 68 | 20 |
| AMP PEAK 31(17Q11.2) WILD-TYPE | 52 | 30 | 24 | 64 | 54 |
Figure S144. Get High-res Image Gene #31: 'amp_17q11.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S145. Gene #32: 'amp_17q12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 32(17Q12) MUTATED | 53 | 67 | 25 | 20 | 0 |
| AMP PEAK 32(17Q12) WILD-TYPE | 25 | 79 | 96 | 41 | 2 |
Figure S145. Get High-res Image Gene #32: 'amp_17q12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0325 (Fisher's exact test), Q value = 0.078
Table S146. Gene #32: 'amp_17q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 32(17Q12) MUTATED | 43 | 61 | 25 | 36 |
| AMP PEAK 32(17Q12) WILD-TYPE | 95 | 66 | 38 | 44 |
Figure S146. Get High-res Image Gene #32: 'amp_17q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0352 (Fisher's exact test), Q value = 0.083
Table S147. Gene #32: 'amp_17q12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 32(17Q12) MUTATED | 50 | 55 | 59 |
| AMP PEAK 32(17Q12) WILD-TYPE | 68 | 57 | 115 |
Figure S147. Get High-res Image Gene #32: 'amp_17q12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0371 (Fisher's exact test), Q value = 0.087
Table S148. Gene #32: 'amp_17q12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| AMP PEAK 32(17Q12) MUTATED | 33 | 38 | 53 | 10 | 30 |
| AMP PEAK 32(17Q12) WILD-TYPE | 72 | 36 | 61 | 15 | 57 |
Figure S148. Get High-res Image Gene #32: 'amp_17q12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00909 (Fisher's exact test), Q value = 0.03
Table S149. Gene #32: 'amp_17q12' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 32(17Q12) MUTATED | 45 | 28 | 60 | 28 |
| AMP PEAK 32(17Q12) WILD-TYPE | 79 | 23 | 67 | 64 |
Figure S149. Get High-res Image Gene #32: 'amp_17q12' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00909 (Fisher's exact test), Q value = 0.03
Table S150. Gene #32: 'amp_17q12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 32(17Q12) MUTATED | 31 | 33 | 14 | 62 | 21 |
| AMP PEAK 32(17Q12) WILD-TYPE | 56 | 27 | 27 | 70 | 53 |
Figure S150. Get High-res Image Gene #32: 'amp_17q12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S151. Gene #33: 'amp_17q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 33(17Q23.3) MUTATED | 59 | 80 | 31 | 23 | 1 |
| AMP PEAK 33(17Q23.3) WILD-TYPE | 19 | 66 | 90 | 38 | 1 |
Figure S151. Get High-res Image Gene #33: 'amp_17q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0321 (Fisher's exact test), Q value = 0.078
Table S152. Gene #33: 'amp_17q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 33(17Q23.3) MUTATED | 57 | 73 | 25 | 39 |
| AMP PEAK 33(17Q23.3) WILD-TYPE | 81 | 54 | 38 | 41 |
Figure S152. Get High-res Image Gene #33: 'amp_17q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S153. Gene #34: 'amp_19q12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 34(19Q12) MUTATED | 37 | 87 | 17 | 22 | 1 |
| AMP PEAK 34(19Q12) WILD-TYPE | 41 | 59 | 104 | 39 | 1 |
Figure S153. Get High-res Image Gene #34: 'amp_19q12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00235 (Fisher's exact test), Q value = 0.01
Table S154. Gene #34: 'amp_19q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 34(19Q12) MUTATED | 43 | 68 | 24 | 29 |
| AMP PEAK 34(19Q12) WILD-TYPE | 95 | 59 | 39 | 51 |
Figure S154. Get High-res Image Gene #34: 'amp_19q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0427 (Fisher's exact test), Q value = 0.097
Table S155. Gene #34: 'amp_19q12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| AMP PEAK 34(19Q12) MUTATED | 96 | 40 | 28 |
| AMP PEAK 34(19Q12) WILD-TYPE | 170 | 43 | 28 |
Figure S155. Get High-res Image Gene #34: 'amp_19q12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S156. Gene #35: 'amp_19q13.43' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 35(19Q13.43) MUTATED | 35 | 80 | 18 | 22 | 0 |
| AMP PEAK 35(19Q13.43) WILD-TYPE | 43 | 66 | 103 | 39 | 2 |
Figure S156. Get High-res Image Gene #35: 'amp_19q13.43' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00636 (Fisher's exact test), Q value = 0.023
Table S157. Gene #35: 'amp_19q13.43' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| AMP PEAK 35(19Q13.43) MUTATED | 39 | 61 | 21 | 34 |
| AMP PEAK 35(19Q13.43) WILD-TYPE | 99 | 66 | 42 | 46 |
Figure S157. Get High-res Image Gene #35: 'amp_19q13.43' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0472 (Fisher's exact test), Q value = 0.11
Table S158. Gene #35: 'amp_19q13.43' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| AMP PEAK 35(19Q13.43) MUTATED | 42 | 27 | 53 | 29 |
| AMP PEAK 35(19Q13.43) WILD-TYPE | 82 | 24 | 74 | 63 |
Figure S158. Get High-res Image Gene #35: 'amp_19q13.43' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S159. Gene #36: 'amp_20q11.21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 36(20Q11.21) MUTATED | 68 | 112 | 38 | 44 | 1 |
| AMP PEAK 36(20Q11.21) WILD-TYPE | 10 | 34 | 83 | 17 | 1 |
Figure S159. Get High-res Image Gene #36: 'amp_20q11.21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0267 (Fisher's exact test), Q value = 0.068
Table S160. Gene #36: 'amp_20q11.21' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 36(20Q11.21) MUTATED | 87 | 64 | 110 |
| AMP PEAK 36(20Q11.21) WILD-TYPE | 31 | 48 | 64 |
Figure S160. Get High-res Image Gene #36: 'amp_20q11.21' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0469 (Fisher's exact test), Q value = 0.1
Table S161. Gene #36: 'amp_20q11.21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| AMP PEAK 36(20Q11.21) MUTATED | 57 | 48 | 30 | 81 | 43 |
| AMP PEAK 36(20Q11.21) WILD-TYPE | 30 | 12 | 11 | 51 | 31 |
Figure S161. Get High-res Image Gene #36: 'amp_20q11.21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00062
Table S162. Gene #37: 'amp_22q12.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| AMP PEAK 37(22Q12.2) MUTATED | 17 | 45 | 10 | 15 | 0 |
| AMP PEAK 37(22Q12.2) WILD-TYPE | 61 | 101 | 111 | 46 | 2 |
Figure S162. Get High-res Image Gene #37: 'amp_22q12.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.016 (Fisher's exact test), Q value = 0.046
Table S163. Gene #38: 'del_1p36.11' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 1(1P36.11) MUTATED | 35 | 36 | 11 | 9 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 103 | 91 | 52 | 71 |
Figure S163. Get High-res Image Gene #38: 'del_1p36.11' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00028 (Fisher's exact test), Q value = 0.0019
Table S164. Gene #39: 'del_1q32.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 2(1Q32.1) MUTATED | 16 | 33 | 7 | 16 | 0 |
| DEL PEAK 2(1Q32.1) WILD-TYPE | 62 | 113 | 114 | 45 | 2 |
Figure S164. Get High-res Image Gene #39: 'del_1q32.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0279 (Fisher's exact test), Q value = 0.071
Table S165. Gene #39: 'del_1q32.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 2(1Q32.1) MUTATED | 18 | 33 | 11 | 10 |
| DEL PEAK 2(1Q32.1) WILD-TYPE | 120 | 94 | 52 | 70 |
Figure S165. Get High-res Image Gene #39: 'del_1q32.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0447 (Fisher's exact test), Q value = 0.1
Table S166. Gene #39: 'del_1q32.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 2(1Q32.1) MUTATED | 28 | 21 | 22 |
| DEL PEAK 2(1Q32.1) WILD-TYPE | 90 | 91 | 152 |
Figure S166. Get High-res Image Gene #39: 'del_1q32.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00127 (Fisher's exact test), Q value = 0.0061
Table S167. Gene #40: 'del_2q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 3(2Q22.1) MUTATED | 29 | 55 | 24 | 24 | 2 |
| DEL PEAK 3(2Q22.1) WILD-TYPE | 49 | 91 | 97 | 37 | 0 |
Figure S167. Get High-res Image Gene #40: 'del_2q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0077 (Fisher's exact test), Q value = 0.027
Table S168. Gene #40: 'del_2q22.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 3(2Q22.1) MUTATED | 36 | 57 | 18 | 23 |
| DEL PEAK 3(2Q22.1) WILD-TYPE | 102 | 70 | 45 | 57 |
Figure S168. Get High-res Image Gene #40: 'del_2q22.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0022
Table S169. Gene #40: 'del_2q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 3(2Q22.1) MUTATED | 21 | 51 | 8 | 22 | 30 |
| DEL PEAK 3(2Q22.1) WILD-TYPE | 51 | 84 | 30 | 81 | 26 |
Figure S169. Get High-res Image Gene #40: 'del_2q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S170. Gene #41: 'del_2q34' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 4(2Q34) MUTATED | 33 | 85 | 19 | 36 | 1 |
| DEL PEAK 4(2Q34) WILD-TYPE | 45 | 61 | 102 | 25 | 1 |
Figure S170. Get High-res Image Gene #41: 'del_2q34' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00098 (Fisher's exact test), Q value = 0.005
Table S171. Gene #41: 'del_2q34' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 4(2Q34) MUTATED | 47 | 72 | 21 | 34 |
| DEL PEAK 4(2Q34) WILD-TYPE | 91 | 55 | 42 | 46 |
Figure S171. Get High-res Image Gene #41: 'del_2q34' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00662 (Fisher's exact test), Q value = 0.024
Table S172. Gene #41: 'del_2q34' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 4(2Q34) MUTATED | 45 | 39 | 56 |
| DEL PEAK 4(2Q34) WILD-TYPE | 77 | 75 | 48 |
Figure S172. Get High-res Image Gene #41: 'del_2q34' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00767 (Fisher's exact test), Q value = 0.027
Table S173. Gene #41: 'del_2q34' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 4(2Q34) MUTATED | 29 | 64 | 7 | 42 | 30 |
| DEL PEAK 4(2Q34) WILD-TYPE | 43 | 71 | 31 | 61 | 26 |
Figure S173. Get High-res Image Gene #41: 'del_2q34' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S174. Gene #42: 'del_2q37.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 5(2Q37.1) MUTATED | 40 | 100 | 28 | 38 | 1 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 38 | 46 | 93 | 23 | 1 |
Figure S174. Get High-res Image Gene #42: 'del_2q37.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0019
Table S175. Gene #42: 'del_2q37.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 5(2Q37.1) MUTATED | 54 | 80 | 27 | 46 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 84 | 47 | 36 | 34 |
Figure S175. Get High-res Image Gene #42: 'del_2q37.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0434 (Fisher's exact test), Q value = 0.098
Table S176. Gene #42: 'del_2q37.1' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 5(2Q37.1) MUTATED | 55 | 49 | 61 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 67 | 65 | 43 |
Figure S176. Get High-res Image Gene #42: 'del_2q37.1' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0255 (Fisher's exact test), Q value = 0.066
Table S177. Gene #42: 'del_2q37.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 5(2Q37.1) MUTATED | 32 | 79 | 13 | 47 | 33 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 40 | 56 | 25 | 56 | 23 |
Figure S177. Get High-res Image Gene #42: 'del_2q37.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00069
Table S178. Gene #43: 'del_3p14.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 6(3P14.2) MUTATED | 23 | 60 | 18 | 15 | 1 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 55 | 86 | 103 | 46 | 1 |
Figure S178. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0278 (Fisher's exact test), Q value = 0.071
Table S179. Gene #43: 'del_3p14.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 6(3P14.2) MUTATED | 50 | 28 | 13 | 26 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 88 | 99 | 50 | 54 |
Figure S179. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.0011
Table S180. Gene #43: 'del_3p14.2' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 6(3P14.2) MUTATED | 37 | 18 | 42 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 85 | 96 | 62 |
Figure S180. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0104 (Fisher's exact test), Q value = 0.033
Table S181. Gene #43: 'del_3p14.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 6(3P14.2) MUTATED | 28 | 22 | 35 | 12 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 62 | 99 | 63 | 19 |
Figure S181. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S182. Gene #43: 'del_3p14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 6(3P14.2) MUTATED | 12 | 24 | 15 | 48 | 16 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 60 | 111 | 23 | 55 | 40 |
Figure S182. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00035
Table S183. Gene #43: 'del_3p14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 6(3P14.2) MUTATED | 27 | 19 | 69 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 91 | 93 | 105 |
Figure S183. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00094 (Fisher's exact test), Q value = 0.0049
Table S184. Gene #43: 'del_3p14.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 6(3P14.2) MUTATED | 46 | 22 | 21 | 8 | 20 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 59 | 52 | 93 | 17 | 67 |
Figure S184. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00028 (Fisher's exact test), Q value = 0.0019
Table S185. Gene #43: 'del_3p14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 6(3P14.2) MUTATED | 29 | 13 | 29 | 44 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 95 | 38 | 98 | 48 |
Figure S185. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.0014
Table S186. Gene #43: 'del_3p14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 6(3P14.2) MUTATED | 16 | 16 | 16 | 31 | 36 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 71 | 44 | 25 | 101 | 38 |
Figure S186. Get High-res Image Gene #43: 'del_3p14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S187. Gene #44: 'del_4q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 7(4Q22.1) MUTATED | 36 | 74 | 16 | 34 | 1 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 42 | 72 | 105 | 27 | 1 |
Figure S187. Get High-res Image Gene #44: 'del_4q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00112 (Fisher's exact test), Q value = 0.0056
Table S188. Gene #44: 'del_4q22.1' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 7(4Q22.1) MUTATED | 51 | 27 | 48 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 71 | 87 | 56 |
Figure S188. Get High-res Image Gene #44: 'del_4q22.1' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0105 (Fisher's exact test), Q value = 0.033
Table S189. Gene #44: 'del_4q22.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 7(4Q22.1) MUTATED | 43 | 34 | 41 | 8 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 47 | 87 | 57 | 23 |
Figure S189. Get High-res Image Gene #44: 'del_4q22.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0179 (Fisher's exact test), Q value = 0.05
Table S190. Gene #44: 'del_4q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 7(4Q22.1) MUTATED | 26 | 44 | 10 | 50 | 28 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 46 | 91 | 28 | 53 | 28 |
Figure S190. Get High-res Image Gene #44: 'del_4q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00122 (Fisher's exact test), Q value = 0.0061
Table S191. Gene #44: 'del_4q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 7(4Q22.1) MUTATED | 52 | 28 | 78 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 66 | 84 | 96 |
Figure S191. Get High-res Image Gene #44: 'del_4q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0133 (Fisher's exact test), Q value = 0.04
Table S192. Gene #44: 'del_4q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 7(4Q22.1) MUTATED | 53 | 27 | 33 | 13 | 35 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 52 | 47 | 81 | 12 | 52 |
Figure S192. Get High-res Image Gene #44: 'del_4q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0284 (Fisher's exact test), Q value = 0.071
Table S193. Gene #44: 'del_4q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 7(4Q22.1) MUTATED | 32 | 22 | 17 | 43 | 41 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 55 | 38 | 24 | 89 | 33 |
Figure S193. Get High-res Image Gene #44: 'del_4q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S194. Gene #45: 'del_4q34.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 8(4Q34.2) MUTATED | 36 | 85 | 16 | 39 | 1 |
| DEL PEAK 8(4Q34.2) WILD-TYPE | 42 | 61 | 105 | 22 | 1 |
Figure S194. Get High-res Image Gene #45: 'del_4q34.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.041 (Fisher's exact test), Q value = 0.094
Table S195. Gene #45: 'del_4q34.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 8(4Q34.2) MUTATED | 55 | 37 | 82 |
| DEL PEAK 8(4Q34.2) WILD-TYPE | 63 | 75 | 92 |
Figure S195. Get High-res Image Gene #45: 'del_4q34.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S196. Gene #46: 'del_5q12.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 9(5Q12.1) MUTATED | 46 | 102 | 21 | 32 | 1 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 32 | 44 | 100 | 29 | 1 |
Figure S196. Get High-res Image Gene #46: 'del_5q12.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00141 (Fisher's exact test), Q value = 0.0068
Table S197. Gene #46: 'del_5q12.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 9(5Q12.1) MUTATED | 66 | 79 | 21 | 36 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 72 | 48 | 42 | 44 |
Figure S197. Get High-res Image Gene #46: 'del_5q12.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00456 (Fisher's exact test), Q value = 0.018
Table S198. Gene #46: 'del_5q12.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 9(5Q12.1) MUTATED | 73 | 46 | 82 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 45 | 66 | 92 |
Figure S198. Get High-res Image Gene #46: 'del_5q12.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00182 (Fisher's exact test), Q value = 0.0082
Table S199. Gene #46: 'del_5q12.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 9(5Q12.1) MUTATED | 45 | 49 | 46 | 17 | 45 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 60 | 25 | 68 | 8 | 42 |
Figure S199. Get High-res Image Gene #46: 'del_5q12.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0121 (Fisher's exact test), Q value = 0.037
Table S200. Gene #46: 'del_5q12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 9(5Q12.1) MUTATED | 119 | 52 | 31 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 147 | 31 | 25 |
Figure S200. Get High-res Image Gene #46: 'del_5q12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S201. Gene #47: 'del_6p25.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 10(6P25.3) MUTATED | 36 | 47 | 7 | 15 | 1 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 42 | 99 | 114 | 46 | 1 |
Figure S201. Get High-res Image Gene #47: 'del_6p25.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00037 (Fisher's exact test), Q value = 0.0023
Table S202. Gene #47: 'del_6p25.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 10(6P25.3) MUTATED | 25 | 51 | 14 | 16 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 113 | 76 | 49 | 64 |
Figure S202. Get High-res Image Gene #47: 'del_6p25.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0391 (Fisher's exact test), Q value = 0.091
Table S203. Gene #47: 'del_6p25.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 10(6P25.3) MUTATED | 34 | 24 | 38 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 88 | 90 | 66 |
Figure S203. Get High-res Image Gene #47: 'del_6p25.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0148 (Fisher's exact test), Q value = 0.043
Table S204. Gene #47: 'del_6p25.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 10(6P25.3) MUTATED | 42 | 26 | 36 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 76 | 86 | 138 |
Figure S204. Get High-res Image Gene #47: 'del_6p25.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S205. Gene #48: 'del_6q21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 11(6Q21) MUTATED | 54 | 99 | 16 | 21 | 0 |
| DEL PEAK 11(6Q21) WILD-TYPE | 24 | 47 | 105 | 40 | 2 |
Figure S205. Get High-res Image Gene #48: 'del_6q21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00299 (Fisher's exact test), Q value = 0.012
Table S206. Gene #48: 'del_6q21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 11(6Q21) MUTATED | 42 | 48 | 44 | 10 | 45 |
| DEL PEAK 11(6Q21) WILD-TYPE | 63 | 26 | 70 | 15 | 42 |
Figure S206. Get High-res Image Gene #48: 'del_6q21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0147 (Fisher's exact test), Q value = 0.043
Table S207. Gene #48: 'del_6q21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 11(6Q21) MUTATED | 112 | 50 | 27 |
| DEL PEAK 11(6Q21) WILD-TYPE | 154 | 33 | 29 |
Figure S207. Get High-res Image Gene #48: 'del_6q21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00625 (Fisher's exact test), Q value = 0.023
Table S208. Gene #48: 'del_6q21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 11(6Q21) MUTATED | 36 | 37 | 27 | 58 | 29 |
| DEL PEAK 11(6Q21) WILD-TYPE | 51 | 23 | 14 | 74 | 45 |
Figure S208. Get High-res Image Gene #48: 'del_6q21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S209. Gene #49: 'del_6q27' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 12(6Q27) MUTATED | 55 | 100 | 14 | 21 | 0 |
| DEL PEAK 12(6Q27) WILD-TYPE | 23 | 46 | 107 | 40 | 2 |
Figure S209. Get High-res Image Gene #49: 'del_6q27' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.034
Table S210. Gene #49: 'del_6q27' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 12(6Q27) MUTATED | 69 | 47 | 73 |
| DEL PEAK 12(6Q27) WILD-TYPE | 49 | 65 | 101 |
Figure S210. Get High-res Image Gene #49: 'del_6q27' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0137 (Fisher's exact test), Q value = 0.041
Table S211. Gene #49: 'del_6q27' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 12(6Q27) MUTATED | 39 | 46 | 48 | 12 | 44 |
| DEL PEAK 12(6Q27) WILD-TYPE | 66 | 28 | 66 | 13 | 43 |
Figure S211. Get High-res Image Gene #49: 'del_6q27' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0108 (Fisher's exact test), Q value = 0.034
Table S212. Gene #49: 'del_6q27' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 12(6Q27) MUTATED | 111 | 50 | 28 |
| DEL PEAK 12(6Q27) WILD-TYPE | 155 | 33 | 28 |
Figure S212. Get High-res Image Gene #49: 'del_6q27' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00281 (Fisher's exact test), Q value = 0.012
Table S213. Gene #49: 'del_6q27' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 12(6Q27) MUTATED | 37 | 37 | 28 | 56 | 29 |
| DEL PEAK 12(6Q27) WILD-TYPE | 50 | 23 | 13 | 76 | 45 |
Figure S213. Get High-res Image Gene #49: 'del_6q27' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00051 (Fisher's exact test), Q value = 0.003
Table S214. Gene #50: 'del_7q36.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 13(7Q36.3) MUTATED | 10 | 28 | 6 | 16 | 0 |
| DEL PEAK 13(7Q36.3) WILD-TYPE | 68 | 118 | 115 | 45 | 2 |
Figure S214. Get High-res Image Gene #50: 'del_7q36.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0325 (Fisher's exact test), Q value = 0.078
Table S215. Gene #50: 'del_7q36.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 13(7Q36.3) MUTATED | 7 | 15 | 3 | 23 | 12 |
| DEL PEAK 13(7Q36.3) WILD-TYPE | 65 | 120 | 35 | 80 | 44 |
Figure S215. Get High-res Image Gene #50: 'del_7q36.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0208 (Fisher's exact test), Q value = 0.057
Table S216. Gene #50: 'del_7q36.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 13(7Q36.3) MUTATED | 11 | 6 | 21 | 22 |
| DEL PEAK 13(7Q36.3) WILD-TYPE | 113 | 45 | 106 | 70 |
Figure S216. Get High-res Image Gene #50: 'del_7q36.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0297 (Fisher's exact test), Q value = 0.074
Table S217. Gene #50: 'del_7q36.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 13(7Q36.3) MUTATED | 5 | 10 | 5 | 24 | 16 |
| DEL PEAK 13(7Q36.3) WILD-TYPE | 82 | 50 | 36 | 108 | 58 |
Figure S217. Get High-res Image Gene #50: 'del_7q36.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S218. Gene #51: 'del_8p23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 14(8P23.3) MUTATED | 30 | 130 | 34 | 48 | 1 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 48 | 16 | 87 | 13 | 1 |
Figure S218. Get High-res Image Gene #51: 'del_8p23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S219. Gene #51: 'del_8p23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 14(8P23.3) MUTATED | 89 | 93 | 22 | 39 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 49 | 34 | 41 | 41 |
Figure S219. Get High-res Image Gene #51: 'del_8p23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00841 (Fisher's exact test), Q value = 0.029
Table S220. Gene #51: 'del_8p23.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 14(8P23.3) MUTATED | 57 | 56 | 66 | 20 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 33 | 65 | 32 | 11 |
Figure S220. Get High-res Image Gene #51: 'del_8p23.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00049
Table S221. Gene #51: 'del_8p23.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 14(8P23.3) MUTATED | 46 | 74 | 11 | 70 | 41 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 26 | 61 | 27 | 33 | 15 |
Figure S221. Get High-res Image Gene #51: 'del_8p23.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.00097
Table S222. Gene #51: 'del_8p23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 14(8P23.3) MUTATED | 85 | 51 | 106 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 33 | 61 | 68 |
Figure S222. Get High-res Image Gene #51: 'del_8p23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00979 (Fisher's exact test), Q value = 0.032
Table S223. Gene #51: 'del_8p23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 14(8P23.3) MUTATED | 144 | 58 | 39 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 122 | 25 | 17 |
Figure S223. Get High-res Image Gene #51: 'del_8p23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S224. Gene #52: 'del_8p21.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 15(8P21.3) MUTATED | 33 | 135 | 34 | 49 | 1 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 45 | 11 | 87 | 12 | 1 |
Figure S224. Get High-res Image Gene #52: 'del_8p21.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S225. Gene #52: 'del_8p21.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 15(8P21.3) MUTATED | 90 | 95 | 25 | 42 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 48 | 32 | 38 | 38 |
Figure S225. Get High-res Image Gene #52: 'del_8p21.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0336 (Fisher's exact test), Q value = 0.08
Table S226. Gene #52: 'del_8p21.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 15(8P21.3) MUTATED | 60 | 62 | 67 | 21 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 30 | 59 | 31 | 10 |
Figure S226. Get High-res Image Gene #52: 'del_8p21.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00091 (Fisher's exact test), Q value = 0.0048
Table S227. Gene #52: 'del_8p21.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 15(8P21.3) MUTATED | 46 | 80 | 13 | 76 | 36 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 26 | 55 | 25 | 27 | 20 |
Figure S227. Get High-res Image Gene #52: 'del_8p21.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00865 (Fisher's exact test), Q value = 0.029
Table S228. Gene #52: 'del_8p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 15(8P21.3) MUTATED | 83 | 57 | 111 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 35 | 55 | 63 |
Figure S228. Get High-res Image Gene #52: 'del_8p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00448 (Fisher's exact test), Q value = 0.017
Table S229. Gene #52: 'del_8p21.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 15(8P21.3) MUTATED | 150 | 63 | 37 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 116 | 20 | 19 |
Figure S229. Get High-res Image Gene #52: 'del_8p21.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0497 (Fisher's exact test), Q value = 0.11
Table S230. Gene #52: 'del_8p21.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 15(8P21.3) MUTATED | 75 | 36 | 69 | 65 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 49 | 15 | 58 | 27 |
Figure S230. Get High-res Image Gene #52: 'del_8p21.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0419 (Fisher's exact test), Q value = 0.096
Table S231. Gene #52: 'del_8p21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 15(8P21.3) MUTATED | 47 | 46 | 27 | 76 | 49 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 40 | 14 | 14 | 56 | 25 |
Figure S231. Get High-res Image Gene #52: 'del_8p21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S232. Gene #53: 'del_9p23' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 16(9P23) MUTATED | 32 | 89 | 52 | 3 | 1 |
| DEL PEAK 16(9P23) WILD-TYPE | 46 | 57 | 69 | 58 | 1 |
Figure S232. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00098 (Fisher's exact test), Q value = 0.005
Table S233. Gene #53: 'del_9p23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 16(9P23) MUTATED | 41 | 65 | 31 | 40 |
| DEL PEAK 16(9P23) WILD-TYPE | 97 | 62 | 32 | 40 |
Figure S233. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0216 (Fisher's exact test), Q value = 0.058
Table S234. Gene #53: 'del_9p23' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 16(9P23) MUTATED | 44 | 61 | 42 |
| DEL PEAK 16(9P23) WILD-TYPE | 78 | 53 | 62 |
Figure S234. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00463 (Fisher's exact test), Q value = 0.018
Table S235. Gene #53: 'del_9p23' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 16(9P23) MUTATED | 39 | 66 | 30 | 12 |
| DEL PEAK 16(9P23) WILD-TYPE | 51 | 55 | 68 | 19 |
Figure S235. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0028
Table S236. Gene #53: 'del_9p23' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 16(9P23) MUTATED | 31 | 66 | 26 | 30 | 24 |
| DEL PEAK 16(9P23) WILD-TYPE | 41 | 69 | 12 | 73 | 32 |
Figure S236. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00024 (Fisher's exact test), Q value = 0.0017
Table S237. Gene #53: 'del_9p23' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 16(9P23) MUTATED | 61 | 60 | 56 |
| DEL PEAK 16(9P23) WILD-TYPE | 57 | 52 | 118 |
Figure S237. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00272 (Fisher's exact test), Q value = 0.012
Table S238. Gene #53: 'del_9p23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 16(9P23) MUTATED | 29 | 39 | 57 | 12 | 39 |
| DEL PEAK 16(9P23) WILD-TYPE | 76 | 35 | 57 | 13 | 48 |
Figure S238. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00026
Table S239. Gene #53: 'del_9p23' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 16(9P23) MUTATED | 57 | 28 | 66 | 21 |
| DEL PEAK 16(9P23) WILD-TYPE | 67 | 23 | 61 | 71 |
Figure S239. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00286 (Fisher's exact test), Q value = 0.012
Table S240. Gene #53: 'del_9p23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 16(9P23) MUTATED | 35 | 33 | 22 | 63 | 19 |
| DEL PEAK 16(9P23) WILD-TYPE | 52 | 27 | 19 | 69 | 55 |
Figure S240. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S241. Gene #54: 'del_9p21.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 17(9P21.3) MUTATED | 47 | 105 | 77 | 9 | 1 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 31 | 41 | 44 | 52 | 1 |
Figure S241. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00591 (Fisher's exact test), Q value = 0.021
Table S242. Gene #54: 'del_9p21.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 17(9P21.3) MUTATED | 48 | 83 | 47 | 22 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 42 | 38 | 51 | 9 |
Figure S242. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00037 (Fisher's exact test), Q value = 0.0023
Table S243. Gene #54: 'del_9p21.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 17(9P21.3) MUTATED | 36 | 85 | 33 | 51 | 33 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 36 | 50 | 5 | 52 | 23 |
Figure S243. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0223 (Fisher's exact test), Q value = 0.059
Table S244. Gene #54: 'del_9p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 17(9P21.3) MUTATED | 75 | 74 | 89 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 43 | 38 | 85 |
Figure S244. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00414 (Fisher's exact test), Q value = 0.016
Table S245. Gene #54: 'del_9p21.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 17(9P21.3) MUTATED | 74 | 35 | 83 | 40 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 50 | 16 | 44 | 52 |
Figure S245. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0119 (Fisher's exact test), Q value = 0.036
Table S246. Gene #54: 'del_9p21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 17(9P21.3) MUTATED | 44 | 41 | 31 | 80 | 36 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 43 | 19 | 10 | 52 | 38 |
Figure S246. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S247. Gene #55: 'del_9q22.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 18(9Q22.33) MUTATED | 39 | 77 | 53 | 9 | 0 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 39 | 69 | 68 | 52 | 2 |
Figure S247. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S248. Gene #55: 'del_9q22.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 18(9Q22.33) MUTATED | 36 | 67 | 33 | 42 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 102 | 60 | 30 | 38 |
Figure S248. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0022
Table S249. Gene #55: 'del_9q22.33' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 18(9Q22.33) MUTATED | 44 | 66 | 35 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 78 | 48 | 69 |
Figure S249. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S250. Gene #55: 'del_9q22.33' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 18(9Q22.33) MUTATED | 40 | 76 | 21 | 8 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 50 | 45 | 77 | 23 |
Figure S250. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S251. Gene #55: 'del_9q22.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 18(9Q22.33) MUTATED | 30 | 75 | 26 | 21 | 26 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 42 | 60 | 12 | 82 | 30 |
Figure S251. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S252. Gene #55: 'del_9q22.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 18(9Q22.33) MUTATED | 64 | 68 | 46 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 54 | 44 | 128 |
Figure S252. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S253. Gene #55: 'del_9q22.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 18(9Q22.33) MUTATED | 25 | 35 | 70 | 11 | 36 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 80 | 39 | 44 | 14 | 51 |
Figure S253. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S254. Gene #55: 'del_9q22.33' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 18(9Q22.33) MUTATED | 52 | 29 | 77 | 15 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 72 | 22 | 50 | 77 |
Figure S254. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S255. Gene #55: 'del_9q22.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 18(9Q22.33) MUTATED | 34 | 34 | 20 | 73 | 12 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 53 | 26 | 21 | 59 | 62 |
Figure S255. Get High-res Image Gene #55: 'del_9q22.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.012 (Fisher's exact test), Q value = 0.037
Table S256. Gene #56: 'del_10p11.21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 19(10P11.21) MUTATED | 15 | 33 | 11 | 14 | 1 |
| DEL PEAK 19(10P11.21) WILD-TYPE | 63 | 113 | 110 | 47 | 1 |
Figure S256. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0308 (Fisher's exact test), Q value = 0.075
Table S257. Gene #56: 'del_10p11.21' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 19(10P11.21) MUTATED | 7 | 18 | 10 | 25 | 12 |
| DEL PEAK 19(10P11.21) WILD-TYPE | 65 | 117 | 28 | 78 | 44 |
Figure S257. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S258. Gene #57: 'del_10q23.31' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 20(10Q23.31) MUTATED | 46 | 71 | 18 | 33 | 0 |
| DEL PEAK 20(10Q23.31) WILD-TYPE | 32 | 75 | 103 | 28 | 2 |
Figure S258. Get High-res Image Gene #57: 'del_10q23.31' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0275 (Fisher's exact test), Q value = 0.07
Table S259. Gene #57: 'del_10q23.31' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 20(10Q23.31) MUTATED | 48 | 66 | 23 | 31 |
| DEL PEAK 20(10Q23.31) WILD-TYPE | 90 | 61 | 40 | 49 |
Figure S259. Get High-res Image Gene #57: 'del_10q23.31' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S260. Gene #58: 'del_11p15.5' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 21(11P15.5) MUTATED | 46 | 113 | 35 | 16 | 1 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 32 | 33 | 86 | 45 | 1 |
Figure S260. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0038
Table S261. Gene #58: 'del_11p15.5' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 21(11P15.5) MUTATED | 52 | 77 | 38 | 44 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 86 | 50 | 25 | 36 |
Figure S261. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.0016
Table S262. Gene #58: 'del_11p15.5' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 21(11P15.5) MUTATED | 56 | 72 | 37 | 10 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 34 | 49 | 61 | 21 |
Figure S262. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00293 (Fisher's exact test), Q value = 0.012
Table S263. Gene #58: 'del_11p15.5' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 21(11P15.5) MUTATED | 36 | 86 | 21 | 40 | 25 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 36 | 49 | 17 | 63 | 31 |
Figure S263. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S264. Gene #58: 'del_11p15.5' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 21(11P15.5) MUTATED | 76 | 66 | 66 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 42 | 46 | 108 |
Figure S264. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00018 (Fisher's exact test), Q value = 0.0013
Table S265. Gene #58: 'del_11p15.5' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 21(11P15.5) MUTATED | 35 | 48 | 69 | 13 | 45 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 70 | 26 | 45 | 12 | 42 |
Figure S265. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0182 (Fisher's exact test), Q value = 0.051
Table S266. Gene #58: 'del_11p15.5' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 21(11P15.5) MUTATED | 126 | 54 | 30 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 140 | 29 | 26 |
Figure S266. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00081 (Fisher's exact test), Q value = 0.0044
Table S267. Gene #58: 'del_11p15.5' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 21(11P15.5) MUTATED | 72 | 31 | 71 | 31 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 52 | 20 | 56 | 61 |
Figure S267. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00188 (Fisher's exact test), Q value = 0.0084
Table S268. Gene #58: 'del_11p15.5' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 21(11P15.5) MUTATED | 45 | 41 | 24 | 70 | 25 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 42 | 19 | 17 | 62 | 49 |
Figure S268. Get High-res Image Gene #58: 'del_11p15.5' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S269. Gene #59: 'del_11q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 22(11Q23.3) MUTATED | 39 | 70 | 24 | 19 | 1 |
| DEL PEAK 22(11Q23.3) WILD-TYPE | 39 | 76 | 97 | 42 | 1 |
Figure S269. Get High-res Image Gene #59: 'del_11q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S270. Gene #60: 'del_11q25' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 23(11Q25) MUTATED | 34 | 71 | 20 | 17 | 2 |
| DEL PEAK 23(11Q25) WILD-TYPE | 44 | 75 | 101 | 44 | 0 |
Figure S270. Get High-res Image Gene #60: 'del_11q25' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0154 (Fisher's exact test), Q value = 0.045
Table S271. Gene #61: 'del_12p13.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 24(12P13.1) MUTATED | 12 | 34 | 11 | 10 | 1 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 66 | 112 | 110 | 51 | 1 |
Figure S271. Get High-res Image Gene #61: 'del_12p13.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00514 (Fisher's exact test), Q value = 0.019
Table S272. Gene #61: 'del_12p13.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 24(12P13.1) MUTATED | 14 | 33 | 11 | 10 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 124 | 94 | 52 | 70 |
Figure S272. Get High-res Image Gene #61: 'del_12p13.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S273. Gene #61: 'del_12p13.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 24(12P13.1) MUTATED | 16 | 36 | 4 | 5 | 6 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 56 | 99 | 34 | 98 | 50 |
Figure S273. Get High-res Image Gene #61: 'del_12p13.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00042
Table S274. Gene #61: 'del_12p13.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 24(12P13.1) MUTATED | 34 | 18 | 15 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 84 | 94 | 159 |
Figure S274. Get High-res Image Gene #61: 'del_12p13.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00994 (Fisher's exact test), Q value = 0.032
Table S275. Gene #61: 'del_12p13.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 24(12P13.1) MUTATED | 7 | 15 | 24 | 3 | 19 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 98 | 59 | 90 | 22 | 68 |
Figure S275. Get High-res Image Gene #61: 'del_12p13.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0118 (Fisher's exact test), Q value = 0.036
Table S276. Gene #61: 'del_12p13.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 24(12P13.1) MUTATED | 26 | 11 | 24 | 6 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 98 | 40 | 103 | 86 |
Figure S276. Get High-res Image Gene #61: 'del_12p13.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S277. Gene #62: 'del_12q24.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 25(12Q24.33) MUTATED | 14 | 42 | 9 | 22 | 1 |
| DEL PEAK 25(12Q24.33) WILD-TYPE | 64 | 104 | 112 | 39 | 1 |
Figure S277. Get High-res Image Gene #62: 'del_12q24.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0218 (Fisher's exact test), Q value = 0.058
Table S278. Gene #62: 'del_12q24.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 25(12Q24.33) MUTATED | 19 | 35 | 3 | 24 | 6 |
| DEL PEAK 25(12Q24.33) WILD-TYPE | 53 | 100 | 35 | 79 | 50 |
Figure S278. Get High-res Image Gene #62: 'del_12q24.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S279. Gene #63: 'del_13q14.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 26(13Q14.2) MUTATED | 45 | 53 | 13 | 43 | 2 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 33 | 93 | 108 | 18 | 0 |
Figure S279. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00026
Table S280. Gene #63: 'del_13q14.2' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 26(13Q14.2) MUTATED | 43 | 30 | 59 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 79 | 84 | 45 |
Figure S280. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0163 (Fisher's exact test), Q value = 0.047
Table S281. Gene #63: 'del_13q14.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 26(13Q14.2) MUTATED | 36 | 40 | 49 | 7 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 54 | 81 | 49 | 24 |
Figure S281. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0161 (Fisher's exact test), Q value = 0.046
Table S282. Gene #63: 'del_13q14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 26(13Q14.2) MUTATED | 26 | 41 | 10 | 50 | 26 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 46 | 94 | 28 | 53 | 30 |
Figure S282. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00977 (Fisher's exact test), Q value = 0.032
Table S283. Gene #63: 'del_13q14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 26(13Q14.2) MUTATED | 43 | 31 | 79 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 75 | 81 | 95 |
Figure S283. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00104 (Fisher's exact test), Q value = 0.0053
Table S284. Gene #63: 'del_13q14.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 26(13Q14.2) MUTATED | 53 | 29 | 33 | 15 | 26 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 52 | 45 | 81 | 10 | 61 |
Figure S284. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00721 (Fisher's exact test), Q value = 0.026
Table S285. Gene #63: 'del_13q14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 26(13Q14.2) MUTATED | 38 | 17 | 50 | 49 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 86 | 34 | 77 | 43 |
Figure S285. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00215 (Fisher's exact test), Q value = 0.0094
Table S286. Gene #63: 'del_13q14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 26(13Q14.2) MUTATED | 26 | 23 | 15 | 46 | 44 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 61 | 37 | 26 | 86 | 30 |
Figure S286. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S287. Gene #64: 'del_14q24.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 27(14Q24.1) MUTATED | 31 | 83 | 10 | 13 | 0 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 47 | 63 | 111 | 48 | 2 |
Figure S287. Get High-res Image Gene #64: 'del_14q24.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S288. Gene #64: 'del_14q24.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 27(14Q24.1) MUTATED | 36 | 66 | 23 | 12 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 102 | 61 | 40 | 68 |
Figure S288. Get High-res Image Gene #64: 'del_14q24.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00145 (Fisher's exact test), Q value = 0.0069
Table S289. Gene #64: 'del_14q24.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 27(14Q24.1) MUTATED | 27 | 56 | 8 | 21 | 24 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 45 | 79 | 30 | 82 | 32 |
Figure S289. Get High-res Image Gene #64: 'del_14q24.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S290. Gene #64: 'del_14q24.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 27(14Q24.1) MUTATED | 64 | 35 | 37 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 54 | 77 | 137 |
Figure S290. Get High-res Image Gene #64: 'del_14q24.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00369 (Fisher's exact test), Q value = 0.015
Table S291. Gene #64: 'del_14q24.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 27(14Q24.1) MUTATED | 23 | 37 | 38 | 9 | 29 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 82 | 37 | 76 | 16 | 58 |
Figure S291. Get High-res Image Gene #64: 'del_14q24.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00416 (Fisher's exact test), Q value = 0.016
Table S292. Gene #64: 'del_14q24.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 27(14Q24.1) MUTATED | 76 | 40 | 20 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 190 | 43 | 36 |
Figure S292. Get High-res Image Gene #64: 'del_14q24.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00161 (Fisher's exact test), Q value = 0.0075
Table S293. Gene #64: 'del_14q24.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 27(14Q24.1) MUTATED | 50 | 25 | 40 | 19 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 74 | 26 | 87 | 73 |
Figure S293. Get High-res Image Gene #64: 'del_14q24.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0019
Table S294. Gene #64: 'del_14q24.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 27(14Q24.1) MUTATED | 27 | 31 | 20 | 43 | 13 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 60 | 29 | 21 | 89 | 61 |
Figure S294. Get High-res Image Gene #64: 'del_14q24.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S295. Gene #65: 'del_15q13.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 28(15Q13.1) MUTATED | 38 | 79 | 9 | 33 | 1 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 40 | 67 | 112 | 28 | 1 |
Figure S295. Get High-res Image Gene #65: 'del_15q13.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00226 (Fisher's exact test), Q value = 0.0098
Table S296. Gene #65: 'del_15q13.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 28(15Q13.1) MUTATED | 56 | 63 | 14 | 27 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 82 | 64 | 49 | 53 |
Figure S296. Get High-res Image Gene #65: 'del_15q13.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00899 (Fisher's exact test), Q value = 0.03
Table S297. Gene #65: 'del_15q13.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 28(15Q13.1) MUTATED | 26 | 51 | 6 | 47 | 27 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 46 | 84 | 32 | 56 | 29 |
Figure S297. Get High-res Image Gene #65: 'del_15q13.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0397 (Fisher's exact test), Q value = 0.092
Table S298. Gene #65: 'del_15q13.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 28(15Q13.1) MUTATED | 41 | 41 | 39 | 8 | 31 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 64 | 33 | 75 | 17 | 56 |
Figure S298. Get High-res Image Gene #65: 'del_15q13.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0104 (Fisher's exact test), Q value = 0.033
Table S299. Gene #65: 'del_15q13.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 28(15Q13.1) MUTATED | 95 | 45 | 20 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 171 | 38 | 36 |
Figure S299. Get High-res Image Gene #65: 'del_15q13.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.019 (Fisher's exact test), Q value = 0.052
Table S300. Gene #65: 'del_15q13.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 28(15Q13.1) MUTATED | 41 | 29 | 46 | 41 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 83 | 22 | 81 | 51 |
Figure S300. Get High-res Image Gene #65: 'del_15q13.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S301. Gene #66: 'del_16p13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 29(16P13.3) MUTATED | 41 | 80 | 9 | 43 | 1 |
| DEL PEAK 29(16P13.3) WILD-TYPE | 37 | 66 | 112 | 18 | 1 |
Figure S301. Get High-res Image Gene #66: 'del_16p13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0186 (Fisher's exact test), Q value = 0.052
Table S302. Gene #66: 'del_16p13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 29(16P13.3) MUTATED | 56 | 66 | 18 | 34 |
| DEL PEAK 29(16P13.3) WILD-TYPE | 82 | 61 | 45 | 46 |
Figure S302. Get High-res Image Gene #66: 'del_16p13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00575 (Fisher's exact test), Q value = 0.021
Table S303. Gene #66: 'del_16p13.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 29(16P13.3) MUTATED | 54 | 36 | 55 |
| DEL PEAK 29(16P13.3) WILD-TYPE | 68 | 78 | 49 |
Figure S303. Get High-res Image Gene #66: 'del_16p13.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00794 (Fisher's exact test), Q value = 0.027
Table S304. Gene #66: 'del_16p13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 29(16P13.3) MUTATED | 32 | 55 | 7 | 51 | 29 |
| DEL PEAK 29(16P13.3) WILD-TYPE | 40 | 80 | 31 | 52 | 27 |
Figure S304. Get High-res Image Gene #66: 'del_16p13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S305. Gene #67: 'del_16q23.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 30(16Q23.1) MUTATED | 45 | 33 | 8 | 33 | 0 |
| DEL PEAK 30(16Q23.1) WILD-TYPE | 33 | 113 | 113 | 28 | 2 |
Figure S305. Get High-res Image Gene #67: 'del_16q23.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00735 (Fisher's exact test), Q value = 0.026
Table S306. Gene #67: 'del_16q23.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 30(16Q23.1) MUTATED | 14 | 37 | 7 | 34 | 26 |
| DEL PEAK 30(16Q23.1) WILD-TYPE | 58 | 98 | 31 | 69 | 30 |
Figure S306. Get High-res Image Gene #67: 'del_16q23.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00534 (Fisher's exact test), Q value = 0.02
Table S307. Gene #67: 'del_16q23.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 30(16Q23.1) MUTATED | 36 | 24 | 27 | 14 | 18 |
| DEL PEAK 30(16Q23.1) WILD-TYPE | 69 | 50 | 87 | 11 | 69 |
Figure S307. Get High-res Image Gene #67: 'del_16q23.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S308. Gene #68: 'del_17p12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 31(17P12) MUTATED | 56 | 100 | 29 | 22 | 1 |
| DEL PEAK 31(17P12) WILD-TYPE | 22 | 46 | 92 | 39 | 1 |
Figure S308. Get High-res Image Gene #68: 'del_17p12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00056 (Fisher's exact test), Q value = 0.0032
Table S309. Gene #68: 'del_17p12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 31(17P12) MUTATED | 61 | 84 | 30 | 33 |
| DEL PEAK 31(17P12) WILD-TYPE | 77 | 43 | 33 | 47 |
Figure S309. Get High-res Image Gene #68: 'del_17p12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.016 (Fisher's exact test), Q value = 0.046
Table S310. Gene #68: 'del_17p12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 31(17P12) MUTATED | 73 | 53 | 79 |
| DEL PEAK 31(17P12) WILD-TYPE | 45 | 59 | 95 |
Figure S310. Get High-res Image Gene #68: 'del_17p12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S311. Gene #69: 'del_18q23' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 32(18Q23) MUTATED | 38 | 86 | 23 | 30 | 2 |
| DEL PEAK 32(18Q23) WILD-TYPE | 40 | 60 | 98 | 31 | 0 |
Figure S311. Get High-res Image Gene #69: 'del_18q23' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0018
Table S312. Gene #69: 'del_18q23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 32(18Q23) MUTATED | 42 | 50 | 41 | 8 | 37 |
| DEL PEAK 32(18Q23) WILD-TYPE | 63 | 24 | 73 | 17 | 50 |
Figure S312. Get High-res Image Gene #69: 'del_18q23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S313. Gene #69: 'del_18q23' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 32(18Q23) MUTATED | 100 | 57 | 21 |
| DEL PEAK 32(18Q23) WILD-TYPE | 166 | 26 | 35 |
Figure S313. Get High-res Image Gene #69: 'del_18q23' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00307 (Fisher's exact test), Q value = 0.013
Table S314. Gene #69: 'del_18q23' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 32(18Q23) MUTATED | 54 | 35 | 49 | 39 |
| DEL PEAK 32(18Q23) WILD-TYPE | 70 | 16 | 78 | 53 |
Figure S314. Get High-res Image Gene #69: 'del_18q23' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00439 (Fisher's exact test), Q value = 0.017
Table S315. Gene #69: 'del_18q23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 32(18Q23) MUTATED | 40 | 40 | 15 | 50 | 32 |
| DEL PEAK 32(18Q23) WILD-TYPE | 47 | 20 | 26 | 82 | 42 |
Figure S315. Get High-res Image Gene #69: 'del_18q23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S316. Gene #70: 'del_19p13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 33(19P13.3) MUTATED | 32 | 72 | 21 | 19 | 1 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 46 | 74 | 100 | 42 | 1 |
Figure S316. Get High-res Image Gene #70: 'del_19p13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0203 (Fisher's exact test), Q value = 0.055
Table S317. Gene #70: 'del_19p13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 33(19P13.3) MUTATED | 24 | 35 | 13 | 45 | 26 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 48 | 100 | 25 | 58 | 30 |
Figure S317. Get High-res Image Gene #70: 'del_19p13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00089 (Fisher's exact test), Q value = 0.0047
Table S318. Gene #70: 'del_19p13.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 33(19P13.3) MUTATED | 49 | 24 | 70 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 69 | 88 | 104 |
Figure S318. Get High-res Image Gene #70: 'del_19p13.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0385 (Fisher's exact test), Q value = 0.09
Table S319. Gene #70: 'del_19p13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 33(19P13.3) MUTATED | 39 | 36 | 31 | 10 | 27 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 66 | 38 | 83 | 15 | 60 |
Figure S319. Get High-res Image Gene #70: 'del_19p13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.7e-05
Table S320. Gene #71: 'del_22q13.32' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 78 | 146 | 121 | 61 | 2 |
| DEL PEAK 34(22Q13.32) MUTATED | 40 | 89 | 10 | 49 | 0 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 38 | 57 | 111 | 12 | 2 |
Figure S320. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00199 (Fisher's exact test), Q value = 0.0088
Table S321. Gene #71: 'del_22q13.32' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 34(22Q13.32) MUTATED | 72 | 65 | 16 | 35 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 66 | 62 | 47 | 45 |
Figure S321. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0297 (Fisher's exact test), Q value = 0.074
Table S322. Gene #71: 'del_22q13.32' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 122 | 114 | 104 |
| DEL PEAK 34(22Q13.32) MUTATED | 66 | 42 | 47 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 56 | 72 | 57 |
Figure S322. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00109 (Fisher's exact test), Q value = 0.0055
Table S323. Gene #71: 'del_22q13.32' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 121 | 98 | 31 |
| DEL PEAK 34(22Q13.32) MUTATED | 55 | 41 | 47 | 12 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 35 | 80 | 51 | 19 |
Figure S323. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00076 (Fisher's exact test), Q value = 0.0042
Table S324. Gene #71: 'del_22q13.32' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 34(22Q13.32) MUTATED | 32 | 53 | 9 | 62 | 28 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 40 | 82 | 29 | 41 | 28 |
Figure S324. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00126 (Fisher's exact test), Q value = 0.0061
Table S325. Gene #71: 'del_22q13.32' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 34(22Q13.32) MUTATED | 58 | 35 | 91 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 60 | 77 | 83 |
Figure S325. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0427 (Fisher's exact test), Q value = 0.097
Table S326. Gene #71: 'del_22q13.32' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 105 | 74 | 114 | 25 | 87 |
| DEL PEAK 34(22Q13.32) MUTATED | 56 | 38 | 39 | 12 | 42 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 49 | 36 | 75 | 13 | 45 |
Figure S326. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0018 (Fisher's exact test), Q value = 0.0081
Table S327. Gene #71: 'del_22q13.32' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 51 | 127 | 92 |
| DEL PEAK 34(22Q13.32) MUTATED | 58 | 20 | 48 | 58 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 66 | 31 | 79 | 34 |
Figure S327. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0166 (Fisher's exact test), Q value = 0.047
Table S328. Gene #71: 'del_22q13.32' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 87 | 60 | 41 | 132 | 74 |
| DEL PEAK 34(22Q13.32) MUTATED | 36 | 27 | 21 | 53 | 47 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 51 | 33 | 20 | 79 | 27 |
Figure S328. Get High-res Image Gene #71: 'del_22q13.32' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0416 (Fisher's exact test), Q value = 0.095
Table S329. Gene #73: 'del_xq21.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 127 | 63 | 80 |
| DEL PEAK 36(XQ21.33) MUTATED | 19 | 33 | 11 | 21 |
| DEL PEAK 36(XQ21.33) WILD-TYPE | 119 | 94 | 52 | 59 |
Figure S329. Get High-res Image Gene #73: 'del_xq21.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0118 (Fisher's exact test), Q value = 0.036
Table S330. Gene #73: 'del_xq21.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 72 | 135 | 38 | 103 | 56 |
| DEL PEAK 36(XQ21.33) MUTATED | 7 | 30 | 12 | 17 | 17 |
| DEL PEAK 36(XQ21.33) WILD-TYPE | 65 | 105 | 26 | 86 | 39 |
Figure S330. Get High-res Image Gene #73: 'del_xq21.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0495 (Fisher's exact test), Q value = 0.11
Table S331. Gene #73: 'del_xq21.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 266 | 83 | 56 |
| DEL PEAK 36(XQ21.33) MUTATED | 60 | 19 | 5 |
| DEL PEAK 36(XQ21.33) WILD-TYPE | 206 | 64 | 51 |
Figure S331. Get High-res Image Gene #73: 'del_xq21.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
-
Copy number data file = all_lesions.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/BLCA-TP/22507728/transformed.cor.cli.txt
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Molecular subtype file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/BLCA-TP/22541056/BLCA-TP.transferedmergedcluster.txt
-
Number of patients = 408
-
Number of significantly focal cnvs = 73
-
Number of molecular subtypes = 10
-
Exclude genes that fewer than K tumors have alterations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.