This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 81 arm-level events and 12 molecular subtypes across 451 patients, 390 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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1q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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2p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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2q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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3p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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3q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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4p gain cnv correlated to 'CN_CNMF'.
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4q gain cnv correlated to 'CN_CNMF'.
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5p gain cnv correlated to 'CN_CNMF'.
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5q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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6p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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6q gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'MIRSEQ_CNMF'.
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7p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'CN_CNMF'.
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8q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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9p gain cnv correlated to 'MRNA_CNMF' and 'CN_CNMF'.
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9q gain cnv correlated to 'MRNA_CNMF' and 'CN_CNMF'.
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10p gain cnv correlated to 'CN_CNMF'.
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10q gain cnv correlated to 'CN_CNMF'.
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11p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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11q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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12p gain cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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12q gain cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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13q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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14q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q gain cnv correlated to 'RPPA_CNMF' and 'RPPA_CHIERARCHICAL'.
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16p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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16q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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17q gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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18p gain cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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18q gain cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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19p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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20q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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22q gain cnv correlated to 'CN_CNMF'.
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xp gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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xq gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', and 'RPPA_CNMF'.
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1p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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1q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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2p loss cnv correlated to 'CN_CNMF'.
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3p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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3q loss cnv correlated to 'CN_CNMF'.
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4p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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4q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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5p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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5q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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6q loss cnv correlated to 'MIRSEQ_MATURE_CNMF'.
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7q loss cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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8p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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8q loss cnv correlated to 'CN_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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9q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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10p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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11p loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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11q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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12p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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12q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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13q loss cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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14q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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15q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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17p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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17q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', and 'MIRSEQ_CNMF'.
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18p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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19q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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20p loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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21q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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22q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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xp loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xq loss cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 81 arm-level events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 390 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 20q gain | 321 (71%) | 130 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00821 (0.0293) |
3e-05 (0.000245) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.0485 (0.122) |
| 7p gain | 246 (55%) | 205 |
6e-05 (0.000449) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
2e-05 (0.000168) |
0.0297 (0.0858) |
0.0022 (0.0102) |
0.00011 (0.000742) |
1e-05 (9.17e-05) |
0.00028 (0.00165) |
2e-05 (0.000168) |
0.0582 (0.139) |
0.0369 (0.101) |
| 7q gain | 223 (49%) | 228 |
0.00032 (0.00186) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00058 (0.0032) |
0.0568 (0.137) |
0.00471 (0.0185) |
0.00541 (0.0209) |
1e-05 (9.17e-05) |
0.00538 (0.0208) |
0.00018 (0.00115) |
0.00145 (0.00701) |
0.0258 (0.0766) |
| 18p loss | 252 (56%) | 199 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.31 (0.483) |
0.00384 (0.0158) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00027 (0.00161) |
0.00109 (0.00546) |
| 18q loss | 268 (59%) | 183 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.409 (0.583) |
0.0128 (0.0428) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00019 (0.00121) |
0.013 (0.0436) |
| 4p loss | 139 (31%) | 312 |
2e-05 (0.000168) |
0.00182 (0.00863) |
1e-05 (9.17e-05) |
0.00802 (0.0289) |
0.919 (0.983) |
0.0357 (0.0986) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00015 (0.000999) |
0.0221 (0.0676) |
0.0139 (0.0457) |
0.0865 (0.187) |
| 8p loss | 138 (31%) | 313 |
0.00244 (0.011) |
0.00441 (0.0178) |
1e-05 (9.17e-05) |
0.0182 (0.0576) |
0.575 (0.734) |
0.0149 (0.0484) |
0.00112 (0.00558) |
1e-05 (9.17e-05) |
0.00033 (0.00191) |
0.0446 (0.114) |
0.0103 (0.036) |
0.159 (0.302) |
| 17p loss | 236 (52%) | 215 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.179 (0.325) |
0.00612 (0.0231) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.0035 (0.0147) |
0.053 (0.13) |
| 16p gain | 106 (24%) | 345 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.0488 (0.122) |
0.0393 (0.104) |
0.107 (0.221) |
0.0041 (0.0168) |
1e-05 (9.17e-05) |
0.0175 (0.0556) |
0.00094 (0.00483) |
0.0858 (0.186) |
0.31 (0.483) |
| 16q gain | 104 (23%) | 347 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.0349 (0.0969) |
0.0452 (0.115) |
0.112 (0.229) |
0.00279 (0.0124) |
1e-05 (9.17e-05) |
0.00964 (0.0339) |
0.00281 (0.0124) |
0.0572 (0.138) |
0.367 (0.54) |
| 20p gain | 244 (54%) | 207 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00275 (0.0123) |
0.045 (0.115) |
0.435 (0.608) |
0.00026 (0.00158) |
1e-05 (9.17e-05) |
0.00077 (0.00409) |
1e-05 (9.17e-05) |
0.144 (0.281) |
0.377 (0.548) |
| 14q loss | 139 (31%) | 312 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
4e-05 (0.000311) |
0.0775 (0.172) |
0.0647 (0.149) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00375 (0.0156) |
0.16 (0.302) |
| 15q loss | 158 (35%) | 293 |
2e-05 (0.000168) |
0.00128 (0.00632) |
1e-05 (9.17e-05) |
0.00034 (0.00194) |
0.128 (0.255) |
0.321 (0.492) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00141 (0.00689) |
0.0422 (0.11) |
0.104 (0.218) |
| 8q gain | 227 (50%) | 224 |
0.0223 (0.0676) |
0.0401 (0.106) |
1e-05 (9.17e-05) |
0.0381 (0.103) |
0.31 (0.483) |
0.103 (0.215) |
0.00089 (0.00465) |
0.00027 (0.00161) |
0.236 (0.396) |
0.00462 (0.0183) |
0.0119 (0.0408) |
0.0842 (0.184) |
| 11p gain | 54 (12%) | 397 |
4e-05 (0.000311) |
0.00068 (0.00369) |
1e-05 (9.17e-05) |
0.00022 (0.00138) |
0.406 (0.582) |
0.137 (0.27) |
0.00278 (0.0124) |
2e-05 (0.000168) |
0.0363 (0.0997) |
0.00227 (0.0104) |
0.41 (0.584) |
0.6 (0.751) |
| 13q gain | 255 (57%) | 196 |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.357 (0.533) |
0.243 (0.404) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00031 (0.00182) |
0.0974 (0.205) |
0.333 (0.505) |
| 19q gain | 84 (19%) | 367 |
0.0452 (0.115) |
0.0264 (0.0779) |
0.00588 (0.0223) |
0.878 (0.96) |
0.0126 (0.0427) |
0.107 (0.222) |
0.339 (0.513) |
0.00016 (0.00104) |
0.00381 (0.0158) |
0.156 (0.296) |
0.0194 (0.061) |
0.00472 (0.0185) |
| 4q loss | 127 (28%) | 324 |
0.00014 (0.000938) |
0.00699 (0.0257) |
1e-05 (9.17e-05) |
0.027 (0.0792) |
0.673 (0.816) |
0.368 (0.54) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00028 (0.00165) |
0.0351 (0.0972) |
0.0754 (0.169) |
0.723 (0.849) |
| 9q loss | 54 (12%) | 397 |
0.002 (0.00935) |
0.0487 (0.122) |
1e-05 (9.17e-05) |
0.00325 (0.014) |
0.818 (0.918) |
0.19 (0.341) |
7e-05 (5e-04) |
0.00097 (0.00494) |
0.00699 (0.0257) |
0.239 (0.4) |
0.041 (0.108) |
0.307 (0.482) |
| 22q loss | 146 (32%) | 305 |
0.00011 (0.000742) |
4e-05 (0.000311) |
1e-05 (9.17e-05) |
0.166 (0.309) |
0.207 (0.363) |
0.0064 (0.0239) |
7e-05 (5e-04) |
1e-05 (9.17e-05) |
0.00023 (0.00142) |
0.00416 (0.0169) |
0.405 (0.582) |
0.885 (0.961) |
| 2p gain | 82 (18%) | 369 |
0.00636 (0.0239) |
0.0375 (0.101) |
1e-05 (9.17e-05) |
0.0153 (0.0494) |
0.32 (0.492) |
0.74 (0.861) |
3e-05 (0.000245) |
0.0033 (0.0142) |
0.0948 (0.2) |
7e-05 (5e-04) |
0.926 (0.983) |
0.847 (0.943) |
| 2q gain | 79 (18%) | 372 |
0.0138 (0.0454) |
0.0392 (0.104) |
1e-05 (9.17e-05) |
0.0372 (0.101) |
0.323 (0.495) |
0.806 (0.911) |
0.00011 (0.000742) |
0.00066 (0.0036) |
0.194 (0.346) |
0.00074 (0.00395) |
0.804 (0.909) |
0.31 (0.483) |
| 11q gain | 51 (11%) | 400 |
2e-05 (0.000168) |
1e-05 (9.17e-05) |
1e-05 (9.17e-05) |
0.00332 (0.0142) |
0.383 (0.555) |
0.0761 (0.169) |
0.00026 (0.00158) |
1e-05 (9.17e-05) |
0.0621 (0.146) |
0.00289 (0.0127) |
0.236 (0.396) |
0.245 (0.406) |
| 17q gain | 84 (19%) | 367 |
0.085 (0.185) |
0.0331 (0.0932) |
1e-05 (9.17e-05) |
0.00191 (0.00901) |
0.592 (0.743) |
0.148 (0.286) |
1e-05 (9.17e-05) |
7e-05 (5e-04) |
0.0478 (0.121) |
0.0234 (0.0703) |
0.24 (0.4) |
0.438 (0.61) |
| 1p loss | 92 (20%) | 359 |
0.0289 (0.0835) |
0.166 (0.309) |
1e-05 (9.17e-05) |
0.00701 (0.0257) |
0.851 (0.944) |
0.0672 (0.154) |
3e-05 (0.000245) |
6e-05 (0.000449) |
0.00157 (0.00752) |
0.00302 (0.0132) |
0.115 (0.233) |
0.574 (0.734) |
| 9p loss | 54 (12%) | 397 |
0.0313 (0.0893) |
0.012 (0.0409) |
1e-05 (9.17e-05) |
0.0131 (0.0436) |
1 (1.00) |
0.218 (0.376) |
7e-05 (5e-04) |
0.00044 (0.00249) |
0.00461 (0.0183) |
0.209 (0.364) |
0.184 (0.333) |
0.341 (0.515) |
| 12p loss | 48 (11%) | 403 |
0.00062 (0.0034) |
0.0156 (0.0502) |
1e-05 (9.17e-05) |
0.00379 (0.0157) |
0.332 (0.505) |
0.895 (0.967) |
0.00333 (0.0142) |
4e-05 (0.000311) |
0.015 (0.0486) |
0.643 (0.794) |
0.175 (0.32) |
0.414 (0.588) |
| 12q loss | 50 (11%) | 401 |
0.00074 (0.00395) |
0.0212 (0.0653) |
1e-05 (9.17e-05) |
0.0142 (0.0462) |
0.418 (0.593) |
0.734 (0.857) |
0.00105 (0.00532) |
0.00011 (0.000742) |
0.00443 (0.0178) |
0.347 (0.52) |
0.577 (0.734) |
0.413 (0.588) |
| 5q loss | 80 (18%) | 371 |
0.0173 (0.055) |
0.203 (0.358) |
1e-05 (9.17e-05) |
0.028 (0.0814) |
0.833 (0.931) |
0.538 (0.707) |
0.00016 (0.00104) |
0.00022 (0.00138) |
0.00414 (0.0169) |
0.11 (0.227) |
0.292 (0.465) |
0.688 (0.831) |
| 10p loss | 68 (15%) | 383 |
0.00086 (0.00452) |
0.0522 (0.128) |
1e-05 (9.17e-05) |
0.00179 (0.00853) |
0.711 (0.847) |
0.442 (0.612) |
0.00016 (0.00104) |
0.0001 (0.000699) |
0.268 (0.435) |
0.171 (0.316) |
0.225 (0.386) |
0.0275 (0.0804) |
| 10q loss | 73 (16%) | 378 |
0.00039 (0.00222) |
0.022 (0.0675) |
1e-05 (9.17e-05) |
0.00197 (0.00925) |
0.419 (0.593) |
0.201 (0.355) |
7e-05 (5e-04) |
2e-05 (0.000168) |
0.0514 (0.127) |
0.264 (0.431) |
0.223 (0.383) |
0.109 (0.224) |
| 21q loss | 124 (27%) | 327 |
4e-05 (0.000311) |
0.0219 (0.0675) |
1e-05 (9.17e-05) |
0.0713 (0.162) |
0.976 (1.00) |
0.341 (0.515) |
2e-05 (0.000168) |
0.0084 (0.0299) |
0.0477 (0.121) |
0.0749 (0.169) |
0.295 (0.47) |
0.815 (0.918) |
| 3p gain | 47 (10%) | 404 |
0.0307 (0.0879) |
0.0383 (0.103) |
2e-05 (0.000168) |
0.0326 (0.0924) |
0.262 (0.429) |
0.0623 (0.146) |
0.754 (0.872) |
0.289 (0.462) |
0.106 (0.221) |
0.274 (0.442) |
0.0228 (0.0687) |
0.415 (0.588) |
| 3q gain | 64 (14%) | 387 |
0.00255 (0.0115) |
0.00126 (0.00625) |
1e-05 (9.17e-05) |
0.0643 (0.149) |
0.562 (0.723) |
0.327 (0.499) |
0.547 (0.714) |
0.0326 (0.0924) |
0.0675 (0.154) |
0.303 (0.477) |
0.00437 (0.0177) |
0.287 (0.46) |
| 6p gain | 84 (19%) | 367 |
0.0329 (0.0928) |
0.00018 (0.00115) |
1e-05 (9.17e-05) |
0.19 (0.341) |
0.149 (0.288) |
0.466 (0.634) |
0.226 (0.386) |
0.00909 (0.0321) |
0.00456 (0.0182) |
0.0806 (0.177) |
0.228 (0.388) |
0.258 (0.425) |
| 19p gain | 73 (16%) | 378 |
0.0674 (0.154) |
0.0891 (0.191) |
6e-05 (0.000449) |
0.389 (0.564) |
0.107 (0.222) |
0.154 (0.296) |
0.276 (0.445) |
0.00011 (0.000742) |
4e-05 (0.000311) |
0.0335 (0.0937) |
0.217 (0.375) |
0.00797 (0.0288) |
| 11q loss | 63 (14%) | 388 |
0.00522 (0.0203) |
0.00055 (0.00305) |
8e-05 (0.000568) |
0.124 (0.25) |
0.528 (0.697) |
0.889 (0.964) |
0.358 (0.534) |
0.00201 (0.00935) |
0.00023 (0.00142) |
0.204 (0.359) |
0.16 (0.302) |
0.905 (0.976) |
| 19p loss | 40 (9%) | 411 |
0.00349 (0.0147) |
0.57 (0.731) |
0.0072 (0.0262) |
0.717 (0.847) |
0.35 (0.524) |
0.669 (0.812) |
0.00649 (0.0241) |
0.0222 (0.0676) |
0.929 (0.985) |
0.0171 (0.0544) |
0.465 (0.633) |
0.195 (0.346) |
| 19q loss | 33 (7%) | 418 |
0.00471 (0.0185) |
0.625 (0.775) |
0.00109 (0.00546) |
0.639 (0.791) |
0.261 (0.428) |
0.138 (0.271) |
0.0135 (0.0447) |
0.0081 (0.0291) |
0.977 (1.00) |
0.207 (0.363) |
0.0417 (0.109) |
0.0639 (0.149) |
| xp loss | 64 (14%) | 387 |
0.303 (0.477) |
0.0441 (0.113) |
0.00045 (0.00253) |
0.363 (0.538) |
0.0206 (0.0641) |
0.269 (0.437) |
0.645 (0.796) |
0.533 (0.703) |
0.15 (0.29) |
0.005 (0.0195) |
0.374 (0.546) |
0.0122 (0.0413) |
| xq loss | 51 (11%) | 400 |
0.131 (0.26) |
0.056 (0.136) |
0.00025 (0.00154) |
0.0925 (0.196) |
0.0871 (0.187) |
0.0196 (0.0613) |
0.309 (0.483) |
0.344 (0.518) |
0.00342 (0.0145) |
0.00708 (0.0259) |
0.24 (0.4) |
0.00145 (0.00701) |
| 1p gain | 40 (9%) | 411 |
0.135 (0.265) |
0.264 (0.431) |
0.0085 (0.0302) |
0.0781 (0.173) |
0.0489 (0.122) |
0.547 (0.714) |
0.615 (0.766) |
0.0303 (0.087) |
0.333 (0.505) |
0.0365 (0.0997) |
0.216 (0.375) |
0.229 (0.389) |
| 18p gain | 23 (5%) | 428 |
0.165 (0.309) |
0.579 (0.734) |
0.053 (0.13) |
0.028 (0.0814) |
0.467 (0.634) |
0.855 (0.946) |
0.039 (0.104) |
6e-05 (0.000449) |
0.0663 (0.152) |
0.0135 (0.0447) |
0.462 (0.631) |
0.773 (0.885) |
| xp gain | 68 (15%) | 383 |
0.00228 (0.0104) |
0.274 (0.442) |
0.00096 (0.00491) |
0.0755 (0.169) |
0.00345 (0.0146) |
0.114 (0.233) |
0.443 (0.612) |
0.0361 (0.0995) |
0.884 (0.961) |
0.912 (0.98) |
0.691 (0.833) |
0.0621 (0.146) |
| 1q loss | 54 (12%) | 397 |
0.88 (0.961) |
0.608 (0.76) |
1e-05 (9.17e-05) |
0.15 (0.288) |
0.91 (0.98) |
0.35 (0.524) |
0.00309 (0.0134) |
0.0102 (0.0357) |
0.0752 (0.169) |
0.0162 (0.0518) |
0.0514 (0.127) |
0.125 (0.251) |
| 5p loss | 60 (13%) | 391 |
0.562 (0.723) |
0.655 (0.804) |
1e-05 (9.17e-05) |
0.0024 (0.0109) |
0.891 (0.964) |
0.796 (0.904) |
0.0898 (0.191) |
0.00054 (0.00302) |
0.0434 (0.113) |
0.505 (0.676) |
0.464 (0.633) |
0.724 (0.849) |
| 11p loss | 51 (11%) | 400 |
0.0862 (0.187) |
0.0271 (0.0793) |
0.00645 (0.024) |
0.501 (0.671) |
0.753 (0.872) |
0.953 (1.00) |
0.133 (0.264) |
0.0436 (0.113) |
0.00093 (0.00481) |
0.133 (0.264) |
0.436 (0.608) |
0.96 (1.00) |
| 20p loss | 43 (10%) | 408 |
0.36 (0.536) |
0.0103 (0.036) |
1e-05 (9.17e-05) |
0.0123 (0.0417) |
0.519 (0.688) |
0.318 (0.49) |
0.0892 (0.191) |
0.0206 (0.0641) |
0.111 (0.228) |
0.439 (0.611) |
0.499 (0.671) |
0.174 (0.32) |
| 6q gain | 76 (17%) | 375 |
0.0978 (0.206) |
0.00027 (0.00161) |
1e-05 (9.17e-05) |
0.223 (0.383) |
0.421 (0.595) |
0.0643 (0.149) |
0.598 (0.75) |
0.103 (0.215) |
0.00785 (0.0285) |
0.197 (0.349) |
0.527 (0.697) |
0.319 (0.49) |
| 18q gain | 14 (3%) | 437 |
0.194 (0.346) |
0.796 (0.904) |
0.0645 (0.149) |
0.177 (0.323) |
0.423 (0.597) |
0.871 (0.958) |
0.0114 (0.0392) |
5e-05 (0.000386) |
0.269 (0.436) |
0.0193 (0.0606) |
0.433 (0.608) |
0.853 (0.945) |
| xq gain | 79 (18%) | 372 |
0.0109 (0.0377) |
0.238 (0.399) |
0.00093 (0.00481) |
0.156 (0.298) |
0.00141 (0.00689) |
0.257 (0.424) |
0.935 (0.989) |
0.374 (0.546) |
0.997 (1.00) |
0.714 (0.847) |
0.757 (0.875) |
0.312 (0.483) |
| 3p loss | 54 (12%) | 397 |
0.208 (0.364) |
0.572 (0.732) |
0.00017 (0.0011) |
0.465 (0.633) |
0.217 (0.376) |
0.993 (1.00) |
0.0393 (0.104) |
0.0604 (0.143) |
0.719 (0.848) |
0.661 (0.807) |
0.0303 (0.087) |
0.71 (0.847) |
| 8q loss | 26 (6%) | 425 |
0.346 (0.519) |
0.364 (0.538) |
0.0001 (0.000699) |
0.587 (0.74) |
0.589 (0.74) |
0.277 (0.446) |
0.734 (0.857) |
0.624 (0.775) |
0.473 (0.64) |
0.587 (0.74) |
0.00289 (0.0127) |
0.00601 (0.0227) |
| 17q loss | 64 (14%) | 387 |
0.0347 (0.0966) |
0.227 (0.388) |
1e-05 (9.17e-05) |
0.914 (0.981) |
0.896 (0.967) |
0.312 (0.483) |
0.577 (0.734) |
0.137 (0.269) |
0.0127 (0.0427) |
0.236 (0.396) |
0.169 (0.313) |
0.163 (0.306) |
| 1q gain | 81 (18%) | 370 |
0.0588 (0.141) |
0.403 (0.58) |
0.00082 (0.00433) |
0.0604 (0.143) |
0.0788 (0.174) |
0.555 (0.721) |
0.428 (0.603) |
0.172 (0.316) |
0.0578 (0.139) |
0.111 (0.228) |
0.00561 (0.0216) |
0.658 (0.807) |
| 5q gain | 42 (9%) | 409 |
0.477 (0.645) |
0.767 (0.882) |
0.00034 (0.00194) |
0.715 (0.847) |
0.543 (0.711) |
0.794 (0.904) |
0.3 (0.474) |
0.123 (0.249) |
0.0759 (0.169) |
0.0403 (0.106) |
0.682 (0.825) |
0.883 (0.961) |
| 9p gain | 81 (18%) | 370 |
0.034 (0.0949) |
0.0642 (0.149) |
0.0138 (0.0454) |
0.768 (0.882) |
0.0797 (0.175) |
0.661 (0.807) |
0.925 (0.983) |
0.648 (0.799) |
0.177 (0.322) |
0.981 (1.00) |
0.26 (0.426) |
0.44 (0.611) |
| 9q gain | 71 (16%) | 380 |
0.0223 (0.0676) |
0.0902 (0.192) |
0.0418 (0.109) |
0.615 (0.766) |
0.0551 (0.134) |
0.612 (0.764) |
0.876 (0.96) |
0.927 (0.984) |
0.145 (0.282) |
0.859 (0.949) |
0.814 (0.918) |
0.772 (0.885) |
| 12p gain | 93 (21%) | 358 |
0.0613 (0.145) |
0.875 (0.96) |
0.0268 (0.0789) |
0.0421 (0.11) |
0.693 (0.835) |
0.436 (0.608) |
0.79 (0.901) |
0.434 (0.608) |
0.127 (0.255) |
0.751 (0.871) |
0.585 (0.74) |
0.989 (1.00) |
| 12q gain | 88 (20%) | 363 |
0.0729 (0.165) |
0.558 (0.723) |
0.0241 (0.0721) |
0.0119 (0.0408) |
0.584 (0.739) |
0.379 (0.551) |
0.556 (0.721) |
0.374 (0.546) |
0.175 (0.32) |
0.664 (0.808) |
0.742 (0.863) |
0.832 (0.931) |
| 14q gain | 35 (8%) | 416 |
0.155 (0.296) |
0.699 (0.838) |
0.00151 (0.00727) |
0.407 (0.582) |
0.859 (0.949) |
0.664 (0.808) |
0.566 (0.727) |
0.577 (0.734) |
0.332 (0.505) |
0.399 (0.576) |
0.141 (0.275) |
0.0335 (0.0937) |
| 15q gain | 11 (2%) | 440 |
0.723 (0.849) |
0.796 (0.904) |
0.172 (0.316) |
1 (1.00) |
0.0387 (0.104) |
0.0144 (0.0468) |
0.818 (0.918) |
0.848 (0.943) |
0.724 (0.849) |
0.889 (0.964) |
||
| 21q gain | 24 (5%) | 427 |
0.245 (0.406) |
0.117 (0.237) |
0.0441 (0.113) |
0.0441 (0.113) |
0.344 (0.518) |
0.567 (0.729) |
0.447 (0.615) |
0.0931 (0.197) |
0.271 (0.438) |
0.868 (0.955) |
||
| 7q loss | 4 (1%) | 447 |
0.0375 (0.101) |
0.0211 (0.0653) |
0.846 (0.943) |
0.726 (0.85) |
0.369 (0.542) |
1 (1.00) |
||||||
| 13q loss | 12 (3%) | 439 |
0.518 (0.688) |
0.449 (0.616) |
0.0109 (0.0377) |
0.0261 (0.0774) |
0.231 (0.393) |
0.0543 (0.133) |
0.54 (0.708) |
0.933 (0.988) |
0.212 (0.369) |
0.923 (0.983) |
0.142 (0.277) |
0.209 (0.364) |
| 4p gain | 12 (3%) | 439 |
0.00574 (0.022) |
0.134 (0.265) |
0.0599 (0.143) |
0.441 (0.612) |
0.161 (0.303) |
0.653 (0.803) |
0.56 (0.723) |
0.266 (0.434) |
||||
| 4q gain | 17 (4%) | 434 |
0.297 (0.472) |
0.167 (0.311) |
0.00579 (0.0221) |
0.538 (0.707) |
0.365 (0.539) |
0.433 (0.608) |
0.39 (0.564) |
0.362 (0.537) |
0.662 (0.807) |
0.0626 (0.147) |
||
| 5p gain | 70 (16%) | 381 |
0.0566 (0.137) |
0.105 (0.22) |
2e-05 (0.000168) |
0.763 (0.879) |
0.183 (0.331) |
0.816 (0.918) |
0.312 (0.483) |
0.0807 (0.177) |
0.249 (0.411) |
0.848 (0.943) |
0.172 (0.316) |
0.667 (0.811) |
| 8p gain | 134 (30%) | 317 |
0.298 (0.472) |
0.937 (0.99) |
1e-05 (9.17e-05) |
0.963 (1.00) |
0.444 (0.612) |
0.715 (0.847) |
0.0735 (0.166) |
0.0876 (0.188) |
0.518 (0.688) |
0.233 (0.393) |
0.451 (0.617) |
0.2 (0.354) |
| 10p gain | 38 (8%) | 413 |
0.408 (0.583) |
0.0519 (0.128) |
0.0228 (0.0687) |
0.544 (0.712) |
1 (1.00) |
0.595 (0.746) |
0.66 (0.807) |
0.397 (0.573) |
0.133 (0.264) |
0.982 (1.00) |
0.0744 (0.168) |
0.851 (0.944) |
| 10q gain | 23 (5%) | 428 |
0.292 (0.465) |
0.376 (0.547) |
0.00221 (0.0102) |
0.0759 (0.169) |
0.191 (0.343) |
0.884 (0.961) |
0.621 (0.772) |
0.579 (0.734) |
0.451 (0.617) |
0.838 (0.936) |
0.153 (0.294) |
0.878 (0.96) |
| 22q gain | 12 (3%) | 439 |
0.919 (0.983) |
1 (1.00) |
0.0364 (0.0997) |
0.223 (0.383) |
0.315 (0.486) |
0.588 (0.74) |
0.159 (0.302) |
0.235 (0.396) |
0.72 (0.848) |
0.763 (0.879) |
0.764 (0.879) |
1 (1.00) |
| 2p loss | 6 (1%) | 445 |
0.479 (0.646) |
0.694 (0.835) |
0.049 (0.122) |
1 (1.00) |
1 (1.00) |
0.142 (0.276) |
0.124 (0.249) |
0.195 (0.346) |
0.632 (0.782) |
|||
| 3q loss | 35 (8%) | 416 |
0.534 (0.703) |
0.917 (0.982) |
0.00069 (0.00373) |
0.702 (0.84) |
0.552 (0.718) |
0.908 (0.979) |
0.0508 (0.126) |
0.187 (0.337) |
0.406 (0.582) |
0.8 (0.906) |
0.361 (0.536) |
0.472 (0.64) |
| 6q loss | 46 (10%) | 405 |
0.881 (0.961) |
0.654 (0.804) |
0.164 (0.308) |
0.365 (0.539) |
0.33 (0.504) |
0.521 (0.69) |
0.435 (0.608) |
0.716 (0.847) |
0.862 (0.951) |
0.713 (0.847) |
0.0254 (0.0756) |
0.11 (0.226) |
| 17p gain | 29 (6%) | 422 |
0.0669 (0.153) |
0.732 (0.857) |
0.797 (0.904) |
0.924 (0.983) |
0.578 (0.734) |
0.923 (0.983) |
0.285 (0.457) |
0.114 (0.232) |
0.298 (0.472) |
0.736 (0.858) |
0.0869 (0.187) |
0.124 (0.249) |
| 2q loss | 7 (2%) | 444 |
0.717 (0.847) |
0.444 (0.612) |
0.155 (0.296) |
0.559 (0.723) |
0.772 (0.885) |
0.373 (0.546) |
0.0634 (0.148) |
0.172 (0.316) |
0.31 (0.483) |
|||
| 6p loss | 34 (8%) | 417 |
0.511 (0.681) |
0.313 (0.484) |
0.193 (0.346) |
0.512 (0.681) |
0.446 (0.614) |
0.818 (0.918) |
0.481 (0.648) |
0.967 (1.00) |
0.557 (0.722) |
0.697 (0.838) |
0.081 (0.177) |
0.185 (0.334) |
| 16p loss | 31 (7%) | 420 |
1 (1.00) |
0.786 (0.897) |
0.233 (0.393) |
0.716 (0.847) |
0.745 (0.865) |
0.478 (0.646) |
0.237 (0.398) |
0.193 (0.346) |
0.868 (0.955) |
0.827 (0.927) |
0.509 (0.68) |
0.975 (1.00) |
| 16q loss | 29 (6%) | 422 |
1 (1.00) |
0.785 (0.897) |
0.168 (0.312) |
0.923 (0.983) |
0.916 (0.982) |
0.491 (0.66) |
0.22 (0.379) |
0.302 (0.476) |
0.702 (0.84) |
0.984 (1.00) |
0.51 (0.68) |
0.974 (1.00) |
| 20q loss | 4 (1%) | 447 |
1 (1.00) |
0.0554 (0.135) |
0.699 (0.838) |
0.258 (0.425) |
0.551 (0.717) |
0.873 (0.958) |
0.681 (0.824) |
P value = 0.0085 (Fisher's exact test), Q value = 0.03
Table S1. Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 1P GAIN MUTATED | 9 | 23 | 8 |
| 1P GAIN WILD-TYPE | 44 | 198 | 169 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0489 (Fisher's exact test), Q value = 0.12
Table S2. Gene #1: '1p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| 1P GAIN MUTATED | 10 | 16 | 5 |
| 1P GAIN WILD-TYPE | 75 | 129 | 120 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0303 (Fisher's exact test), Q value = 0.087
Table S3. Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 1P GAIN MUTATED | 6 | 15 | 3 | 15 | 1 |
| 1P GAIN WILD-TYPE | 73 | 93 | 93 | 114 | 36 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0365 (Fisher's exact test), Q value = 0.1
Table S4. Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 1P GAIN MUTATED | 8 | 4 | 1 | 0 | 1 | 3 | 4 | 4 | 10 |
| 1P GAIN WILD-TYPE | 71 | 51 | 45 | 17 | 54 | 17 | 22 | 38 | 48 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00082 (Fisher's exact test), Q value = 0.0043
Table S5. Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 1Q GAIN MUTATED | 17 | 45 | 19 |
| 1Q GAIN WILD-TYPE | 36 | 176 | 158 |
Figure S5. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00561 (Fisher's exact test), Q value = 0.022
Table S6. Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 1Q GAIN MUTATED | 2 | 4 | 1 | 6 | 0 | 0 |
| 1Q GAIN WILD-TYPE | 16 | 16 | 15 | 5 | 11 | 9 |
Figure S6. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00636 (Fisher's exact test), Q value = 0.024
Table S7. Gene #3: '2p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 2P GAIN MUTATED | 1 | 5 | 7 | 1 | 7 |
| 2P GAIN WILD-TYPE | 30 | 12 | 42 | 26 | 16 |
Figure S7. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0375 (Fisher's exact test), Q value = 0.1
Table S8. Gene #3: '2p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 2P GAIN MUTATED | 2 | 10 | 9 |
| 2P GAIN WILD-TYPE | 40 | 58 | 28 |
Figure S8. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S9. Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 2P GAIN MUTATED | 16 | 53 | 13 |
| 2P GAIN WILD-TYPE | 37 | 168 | 164 |
Figure S9. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0153 (Fisher's exact test), Q value = 0.049
Table S10. Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 2P GAIN MUTATED | 16 | 30 | 14 |
| 2P GAIN WILD-TYPE | 69 | 73 | 92 |
Figure S10. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S11. Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 2P GAIN MUTATED | 41 | 8 | 17 | 16 |
| 2P GAIN WILD-TYPE | 86 | 86 | 80 | 115 |
Figure S11. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0033 (Fisher's exact test), Q value = 0.014
Table S12. Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 2P GAIN MUTATED | 16 | 30 | 12 | 23 | 1 |
| 2P GAIN WILD-TYPE | 63 | 78 | 84 | 106 | 36 |
Figure S12. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 5e-04
Table S13. Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 2P GAIN MUTATED | 12 | 11 | 17 | 2 | 13 | 0 | 5 | 0 | 9 |
| 2P GAIN WILD-TYPE | 67 | 44 | 29 | 15 | 42 | 20 | 21 | 42 | 49 |
Figure S13. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0138 (Fisher's exact test), Q value = 0.045
Table S14. Gene #4: '2q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 2Q GAIN MUTATED | 1 | 5 | 6 | 2 | 7 |
| 2Q GAIN WILD-TYPE | 30 | 12 | 43 | 25 | 16 |
Figure S14. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0392 (Fisher's exact test), Q value = 0.1
Table S15. Gene #4: '2q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 2Q GAIN MUTATED | 2 | 10 | 9 |
| 2Q GAIN WILD-TYPE | 40 | 58 | 28 |
Figure S15. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S16. Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 2Q GAIN MUTATED | 17 | 51 | 11 |
| 2Q GAIN WILD-TYPE | 36 | 170 | 166 |
Figure S16. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0372 (Fisher's exact test), Q value = 0.1
Table S17. Gene #4: '2q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 2Q GAIN MUTATED | 15 | 28 | 14 |
| 2Q GAIN WILD-TYPE | 70 | 75 | 92 |
Figure S17. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00074
Table S18. Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 2Q GAIN MUTATED | 39 | 9 | 15 | 16 |
| 2Q GAIN WILD-TYPE | 88 | 85 | 82 | 115 |
Figure S18. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00066 (Fisher's exact test), Q value = 0.0036
Table S19. Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 2Q GAIN MUTATED | 16 | 30 | 9 | 23 | 1 |
| 2Q GAIN WILD-TYPE | 63 | 78 | 87 | 106 | 36 |
Figure S19. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00074 (Fisher's exact test), Q value = 0.004
Table S20. Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 2Q GAIN MUTATED | 13 | 10 | 14 | 2 | 14 | 0 | 4 | 0 | 9 |
| 2Q GAIN WILD-TYPE | 66 | 45 | 32 | 15 | 41 | 20 | 22 | 42 | 49 |
Figure S20. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0307 (Fisher's exact test), Q value = 0.088
Table S21. Gene #5: '3p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 3P GAIN MUTATED | 1 | 3 | 6 | 0 | 5 |
| 3P GAIN WILD-TYPE | 30 | 14 | 43 | 27 | 18 |
Figure S21. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0383 (Fisher's exact test), Q value = 0.1
Table S22. Gene #5: '3p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 3P GAIN MUTATED | 2 | 5 | 8 |
| 3P GAIN WILD-TYPE | 40 | 63 | 29 |
Figure S22. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S23. Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 3P GAIN MUTATED | 7 | 35 | 5 |
| 3P GAIN WILD-TYPE | 46 | 186 | 172 |
Figure S23. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0326 (Fisher's exact test), Q value = 0.092
Table S24. Gene #5: '3p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 3P GAIN MUTATED | 4 | 17 | 11 |
| 3P GAIN WILD-TYPE | 81 | 86 | 95 |
Figure S24. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0228 (Fisher's exact test), Q value = 0.069
Table S25. Gene #5: '3p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 3P GAIN MUTATED | 4 | 2 | 0 | 2 | 0 | 4 |
| 3P GAIN WILD-TYPE | 14 | 18 | 16 | 9 | 11 | 5 |
Figure S25. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00255 (Fisher's exact test), Q value = 0.011
Table S26. Gene #6: '3q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 3Q GAIN MUTATED | 1 | 4 | 8 | 0 | 7 |
| 3Q GAIN WILD-TYPE | 30 | 13 | 41 | 27 | 16 |
Figure S26. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00126 (Fisher's exact test), Q value = 0.0062
Table S27. Gene #6: '3q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 3Q GAIN MUTATED | 2 | 6 | 12 |
| 3Q GAIN WILD-TYPE | 40 | 62 | 25 |
Figure S27. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S28. Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 3Q GAIN MUTATED | 8 | 50 | 6 |
| 3Q GAIN WILD-TYPE | 45 | 171 | 171 |
Figure S28. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0326 (Fisher's exact test), Q value = 0.092
Table S29. Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 3Q GAIN MUTATED | 15 | 19 | 8 | 21 | 1 |
| 3Q GAIN WILD-TYPE | 64 | 89 | 88 | 108 | 36 |
Figure S29. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00437 (Fisher's exact test), Q value = 0.018
Table S30. Gene #6: '3q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 3Q GAIN MUTATED | 5 | 3 | 0 | 3 | 0 | 5 |
| 3Q GAIN WILD-TYPE | 13 | 17 | 16 | 8 | 11 | 4 |
Figure S30. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00574 (Fisher's exact test), Q value = 0.022
Table S31. Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 4P GAIN MUTATED | 2 | 10 | 0 |
| 4P GAIN WILD-TYPE | 51 | 211 | 177 |
Figure S31. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00579 (Fisher's exact test), Q value = 0.022
Table S32. Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 4Q GAIN MUTATED | 3 | 13 | 1 |
| 4Q GAIN WILD-TYPE | 50 | 208 | 176 |
Figure S32. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S33. Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 5P GAIN MUTATED | 17 | 41 | 12 |
| 5P GAIN WILD-TYPE | 36 | 180 | 165 |
Figure S33. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0019
Table S34. Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 5Q GAIN MUTATED | 10 | 26 | 6 |
| 5Q GAIN WILD-TYPE | 43 | 195 | 171 |
Figure S34. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0403 (Fisher's exact test), Q value = 0.11
Table S35. Gene #10: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 5Q GAIN MUTATED | 7 | 6 | 2 | 1 | 0 | 2 | 5 | 4 | 9 |
| 5Q GAIN WILD-TYPE | 72 | 49 | 44 | 16 | 55 | 18 | 21 | 38 | 49 |
Figure S35. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0329 (Fisher's exact test), Q value = 0.093
Table S36. Gene #11: '6p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 6P GAIN MUTATED | 4 | 5 | 10 | 1 | 8 |
| 6P GAIN WILD-TYPE | 27 | 12 | 39 | 26 | 15 |
Figure S36. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0012
Table S37. Gene #11: '6p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 6P GAIN MUTATED | 4 | 8 | 16 |
| 6P GAIN WILD-TYPE | 38 | 60 | 21 |
Figure S37. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S38. Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 6P GAIN MUTATED | 15 | 58 | 11 |
| 6P GAIN WILD-TYPE | 38 | 163 | 166 |
Figure S38. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00909 (Fisher's exact test), Q value = 0.032
Table S39. Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 6P GAIN MUTATED | 20 | 21 | 9 | 31 | 3 |
| 6P GAIN WILD-TYPE | 59 | 87 | 87 | 98 | 34 |
Figure S39. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00456 (Fisher's exact test), Q value = 0.018
Table S40. Gene #11: '6p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 6P GAIN MUTATED | 17 | 13 | 11 | 22 | 11 |
| 6P GAIN WILD-TYPE | 43 | 75 | 60 | 53 | 93 |
Figure S40. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0016
Table S41. Gene #12: '6q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 6Q GAIN MUTATED | 4 | 5 | 14 |
| 6Q GAIN WILD-TYPE | 38 | 63 | 23 |
Figure S41. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S42. Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 6Q GAIN MUTATED | 9 | 55 | 12 |
| 6Q GAIN WILD-TYPE | 44 | 166 | 165 |
Figure S42. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00785 (Fisher's exact test), Q value = 0.028
Table S43. Gene #12: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 6Q GAIN MUTATED | 16 | 12 | 10 | 20 | 10 |
| 6Q GAIN WILD-TYPE | 44 | 76 | 61 | 55 | 94 |
Figure S43. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00045
Table S44. Gene #13: '7p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 7P GAIN MUTATED | 4 | 11 | 31 | 10 | 13 |
| 7P GAIN WILD-TYPE | 27 | 6 | 18 | 17 | 10 |
Figure S44. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S45. Gene #13: '7p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 7P GAIN MUTATED | 9 | 33 | 27 |
| 7P GAIN WILD-TYPE | 33 | 35 | 10 |
Figure S45. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S46. Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 7P GAIN MUTATED | 40 | 157 | 49 |
| 7P GAIN WILD-TYPE | 13 | 64 | 128 |
Figure S46. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S47. Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 7P GAIN MUTATED | 45 | 79 | 48 |
| 7P GAIN WILD-TYPE | 40 | 24 | 58 |
Figure S47. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0297 (Fisher's exact test), Q value = 0.086
Table S48. Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| 7P GAIN MUTATED | 55 | 74 | 58 |
| 7P GAIN WILD-TYPE | 30 | 71 | 67 |
Figure S48. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0022 (Fisher's exact test), Q value = 0.01
Table S49. Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 7P GAIN MUTATED | 37 | 11 | 20 | 16 | 27 | 38 | 9 | 11 | 18 |
| 7P GAIN WILD-TYPE | 14 | 22 | 15 | 23 | 16 | 48 | 13 | 9 | 8 |
Figure S49. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00011 (Fisher's exact test), Q value = 0.00074
Table S50. Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 7P GAIN MUTATED | 89 | 38 | 52 | 66 |
| 7P GAIN WILD-TYPE | 38 | 56 | 45 | 65 |
Figure S50. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S51. Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 7P GAIN MUTATED | 58 | 71 | 33 | 75 | 8 |
| 7P GAIN WILD-TYPE | 21 | 37 | 63 | 54 | 29 |
Figure S51. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00028 (Fisher's exact test), Q value = 0.0016
Table S52. Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 7P GAIN MUTATED | 43 | 37 | 45 | 48 | 47 |
| 7P GAIN WILD-TYPE | 17 | 51 | 26 | 27 | 57 |
Figure S52. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S53. Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 7P GAIN MUTATED | 51 | 30 | 24 | 3 | 38 | 11 | 15 | 10 | 38 |
| 7P GAIN WILD-TYPE | 28 | 25 | 22 | 14 | 17 | 9 | 11 | 32 | 20 |
Figure S53. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0369 (Fisher's exact test), Q value = 0.1
Table S54. Gene #13: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 7P GAIN MUTATED | 12 | 4 | 7 | 7 | 5 | 5 | 5 | 6 | 4 |
| 7P GAIN WILD-TYPE | 0 | 5 | 1 | 5 | 4 | 2 | 8 | 3 | 2 |
Figure S54. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00032 (Fisher's exact test), Q value = 0.0019
Table S55. Gene #14: '7q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 7Q GAIN MUTATED | 3 | 8 | 27 | 9 | 12 |
| 7Q GAIN WILD-TYPE | 28 | 9 | 22 | 18 | 11 |
Figure S55. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S56. Gene #14: '7q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 7Q GAIN MUTATED | 7 | 28 | 24 |
| 7Q GAIN WILD-TYPE | 35 | 40 | 13 |
Figure S56. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S57. Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 7Q GAIN MUTATED | 36 | 141 | 46 |
| 7Q GAIN WILD-TYPE | 17 | 80 | 131 |
Figure S57. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00058 (Fisher's exact test), Q value = 0.0032
Table S58. Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 7Q GAIN MUTATED | 44 | 70 | 44 |
| 7Q GAIN WILD-TYPE | 41 | 33 | 62 |
Figure S58. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00471 (Fisher's exact test), Q value = 0.018
Table S59. Gene #14: '7q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 7Q GAIN MUTATED | 34 | 8 | 17 | 17 | 21 | 35 | 9 | 10 | 18 |
| 7Q GAIN WILD-TYPE | 17 | 25 | 18 | 22 | 22 | 51 | 13 | 10 | 8 |
Figure S59. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00541 (Fisher's exact test), Q value = 0.021
Table S60. Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 7Q GAIN MUTATED | 78 | 36 | 48 | 60 |
| 7Q GAIN WILD-TYPE | 49 | 58 | 49 | 71 |
Figure S60. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S61. Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 7Q GAIN MUTATED | 54 | 64 | 32 | 67 | 5 |
| 7Q GAIN WILD-TYPE | 25 | 44 | 64 | 62 | 32 |
Figure S61. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00538 (Fisher's exact test), Q value = 0.021
Table S62. Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 7Q GAIN MUTATED | 38 | 35 | 43 | 40 | 43 |
| 7Q GAIN WILD-TYPE | 22 | 53 | 28 | 35 | 61 |
Figure S62. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0012
Table S63. Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 7Q GAIN MUTATED | 49 | 28 | 22 | 3 | 31 | 9 | 13 | 9 | 35 |
| 7Q GAIN WILD-TYPE | 30 | 27 | 24 | 14 | 24 | 11 | 13 | 33 | 23 |
Figure S63. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00145 (Fisher's exact test), Q value = 0.007
Table S64. Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 7Q GAIN MUTATED | 9 | 14 | 8 | 9 | 2 | 9 |
| 7Q GAIN WILD-TYPE | 9 | 6 | 8 | 2 | 9 | 0 |
Figure S64. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0258 (Fisher's exact test), Q value = 0.077
Table S65. Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 7Q GAIN MUTATED | 12 | 4 | 5 | 6 | 5 | 5 | 5 | 7 | 2 |
| 7Q GAIN WILD-TYPE | 0 | 5 | 3 | 6 | 4 | 2 | 8 | 2 | 4 |
Figure S65. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S66. Gene #15: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 8P GAIN MUTATED | 32 | 59 | 43 |
| 8P GAIN WILD-TYPE | 21 | 162 | 134 |
Figure S66. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0223 (Fisher's exact test), Q value = 0.068
Table S67. Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 8Q GAIN MUTATED | 7 | 11 | 22 | 12 | 14 |
| 8Q GAIN WILD-TYPE | 24 | 6 | 27 | 15 | 9 |
Figure S67. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0401 (Fisher's exact test), Q value = 0.11
Table S68. Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 8Q GAIN MUTATED | 13 | 31 | 22 |
| 8Q GAIN WILD-TYPE | 29 | 37 | 15 |
Figure S68. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S69. Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 8Q GAIN MUTATED | 38 | 132 | 57 |
| 8Q GAIN WILD-TYPE | 15 | 89 | 120 |
Figure S69. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0381 (Fisher's exact test), Q value = 0.1
Table S70. Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 8Q GAIN MUTATED | 43 | 66 | 50 |
| 8Q GAIN WILD-TYPE | 42 | 37 | 56 |
Figure S70. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00089 (Fisher's exact test), Q value = 0.0047
Table S71. Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 8Q GAIN MUTATED | 76 | 33 | 56 | 60 |
| 8Q GAIN WILD-TYPE | 51 | 61 | 41 | 71 |
Figure S71. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0016
Table S72. Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 8Q GAIN MUTATED | 48 | 62 | 39 | 68 | 8 |
| 8Q GAIN WILD-TYPE | 31 | 46 | 57 | 61 | 29 |
Figure S72. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00462 (Fisher's exact test), Q value = 0.018
Table S73. Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 8Q GAIN MUTATED | 29 | 34 | 27 | 8 | 36 | 10 | 12 | 13 | 31 |
| 8Q GAIN WILD-TYPE | 50 | 21 | 19 | 9 | 19 | 10 | 14 | 29 | 27 |
Figure S73. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0119 (Fisher's exact test), Q value = 0.041
Table S74. Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 8Q GAIN MUTATED | 12 | 14 | 5 | 9 | 3 | 3 |
| 8Q GAIN WILD-TYPE | 6 | 6 | 11 | 2 | 8 | 6 |
Figure S74. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.034 (Fisher's exact test), Q value = 0.095
Table S75. Gene #17: '9p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 9P GAIN MUTATED | 0 | 2 | 10 | 6 | 4 |
| 9P GAIN WILD-TYPE | 31 | 15 | 39 | 21 | 19 |
Figure S75. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0138 (Fisher's exact test), Q value = 0.045
Table S76. Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 9P GAIN MUTATED | 14 | 46 | 21 |
| 9P GAIN WILD-TYPE | 39 | 175 | 156 |
Figure S76. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0223 (Fisher's exact test), Q value = 0.068
Table S77. Gene #18: '9q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 9Q GAIN MUTATED | 0 | 1 | 10 | 6 | 4 |
| 9Q GAIN WILD-TYPE | 31 | 16 | 39 | 21 | 19 |
Figure S77. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0418 (Fisher's exact test), Q value = 0.11
Table S78. Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 9Q GAIN MUTATED | 14 | 36 | 21 |
| 9Q GAIN WILD-TYPE | 39 | 185 | 156 |
Figure S78. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0228 (Fisher's exact test), Q value = 0.069
Table S79. Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 10P GAIN MUTATED | 8 | 22 | 8 |
| 10P GAIN WILD-TYPE | 45 | 199 | 169 |
Figure S79. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00221 (Fisher's exact test), Q value = 0.01
Table S80. Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 10Q GAIN MUTATED | 8 | 11 | 4 |
| 10Q GAIN WILD-TYPE | 45 | 210 | 173 |
Figure S80. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S81. Gene #21: '11p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 11P GAIN MUTATED | 0 | 2 | 6 | 0 | 9 |
| 11P GAIN WILD-TYPE | 31 | 15 | 43 | 27 | 14 |
Figure S81. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00068 (Fisher's exact test), Q value = 0.0037
Table S82. Gene #21: '11p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 11P GAIN MUTATED | 1 | 5 | 11 |
| 11P GAIN WILD-TYPE | 41 | 63 | 26 |
Figure S82. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S83. Gene #21: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 11P GAIN MUTATED | 7 | 47 | 0 |
| 11P GAIN WILD-TYPE | 46 | 174 | 177 |
Figure S83. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.0014
Table S84. Gene #21: '11p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 11P GAIN MUTATED | 10 | 23 | 4 |
| 11P GAIN WILD-TYPE | 75 | 80 | 102 |
Figure S84. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00278 (Fisher's exact test), Q value = 0.012
Table S85. Gene #21: '11p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 11P GAIN MUTATED | 24 | 3 | 10 | 17 |
| 11P GAIN WILD-TYPE | 103 | 91 | 87 | 114 |
Figure S85. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S86. Gene #21: '11p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 11P GAIN MUTATED | 14 | 17 | 1 | 22 | 0 |
| 11P GAIN WILD-TYPE | 65 | 91 | 95 | 107 | 37 |
Figure S86. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0363 (Fisher's exact test), Q value = 0.1
Table S87. Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 11P GAIN MUTATED | 8 | 6 | 10 | 16 | 8 |
| 11P GAIN WILD-TYPE | 52 | 82 | 61 | 59 | 96 |
Figure S87. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00227 (Fisher's exact test), Q value = 0.01
Table S88. Gene #21: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 11P GAIN MUTATED | 7 | 8 | 8 | 0 | 10 | 0 | 2 | 0 | 13 |
| 11P GAIN WILD-TYPE | 72 | 47 | 38 | 17 | 45 | 20 | 24 | 42 | 45 |
Figure S88. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S89. Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 11Q GAIN MUTATED | 0 | 2 | 5 | 0 | 11 |
| 11Q GAIN WILD-TYPE | 31 | 15 | 44 | 27 | 12 |
Figure S89. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S90. Gene #22: '11q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 11Q GAIN MUTATED | 1 | 4 | 13 |
| 11Q GAIN WILD-TYPE | 41 | 64 | 24 |
Figure S90. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S91. Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 11Q GAIN MUTATED | 8 | 43 | 0 |
| 11Q GAIN WILD-TYPE | 45 | 178 | 177 |
Figure S91. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00332 (Fisher's exact test), Q value = 0.014
Table S92. Gene #22: '11q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 11Q GAIN MUTATED | 8 | 20 | 5 |
| 11Q GAIN WILD-TYPE | 77 | 83 | 101 |
Figure S92. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0016
Table S93. Gene #22: '11q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 11Q GAIN MUTATED | 25 | 2 | 8 | 16 |
| 11Q GAIN WILD-TYPE | 102 | 92 | 89 | 115 |
Figure S93. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S94. Gene #22: '11q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 11Q GAIN MUTATED | 13 | 18 | 0 | 20 | 0 |
| 11Q GAIN WILD-TYPE | 66 | 90 | 96 | 109 | 37 |
Figure S94. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00289 (Fisher's exact test), Q value = 0.013
Table S95. Gene #22: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 11Q GAIN MUTATED | 5 | 7 | 7 | 0 | 11 | 0 | 1 | 1 | 13 |
| 11Q GAIN WILD-TYPE | 74 | 48 | 39 | 17 | 44 | 20 | 25 | 41 | 45 |
Figure S95. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0268 (Fisher's exact test), Q value = 0.079
Table S96. Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 12P GAIN MUTATED | 16 | 35 | 42 |
| 12P GAIN WILD-TYPE | 37 | 186 | 135 |
Figure S96. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0421 (Fisher's exact test), Q value = 0.11
Table S97. Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 12P GAIN MUTATED | 17 | 13 | 28 |
| 12P GAIN WILD-TYPE | 68 | 90 | 78 |
Figure S97. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0241 (Fisher's exact test), Q value = 0.072
Table S98. Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 12Q GAIN MUTATED | 14 | 32 | 42 |
| 12Q GAIN WILD-TYPE | 39 | 189 | 135 |
Figure S98. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0119 (Fisher's exact test), Q value = 0.041
Table S99. Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 12Q GAIN MUTATED | 14 | 11 | 28 |
| 12Q GAIN WILD-TYPE | 71 | 92 | 78 |
Figure S99. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S100. Gene #25: '13q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 13Q GAIN MUTATED | 7 | 13 | 38 | 10 | 17 |
| 13Q GAIN WILD-TYPE | 24 | 4 | 11 | 17 | 6 |
Figure S100. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S101. Gene #25: '13q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 13Q GAIN MUTATED | 11 | 45 | 29 |
| 13Q GAIN WILD-TYPE | 31 | 23 | 8 |
Figure S101. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S102. Gene #25: '13q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 13Q GAIN MUTATED | 37 | 181 | 37 |
| 13Q GAIN WILD-TYPE | 16 | 40 | 140 |
Figure S102. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S103. Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 13Q GAIN MUTATED | 39 | 79 | 49 |
| 13Q GAIN WILD-TYPE | 46 | 24 | 57 |
Figure S103. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S104. Gene #25: '13q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 13Q GAIN MUTATED | 89 | 33 | 54 | 77 |
| 13Q GAIN WILD-TYPE | 38 | 61 | 43 | 54 |
Figure S104. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S105. Gene #25: '13q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 13Q GAIN MUTATED | 61 | 71 | 26 | 87 | 8 |
| 13Q GAIN WILD-TYPE | 18 | 37 | 70 | 42 | 29 |
Figure S105. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S106. Gene #25: '13q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 13Q GAIN MUTATED | 48 | 36 | 42 | 53 | 49 |
| 13Q GAIN WILD-TYPE | 12 | 52 | 29 | 22 | 55 |
Figure S106. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0018
Table S107. Gene #25: '13q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 13Q GAIN MUTATED | 48 | 31 | 24 | 5 | 36 | 11 | 16 | 13 | 44 |
| 13Q GAIN WILD-TYPE | 31 | 24 | 22 | 12 | 19 | 9 | 10 | 29 | 14 |
Figure S107. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00151 (Fisher's exact test), Q value = 0.0073
Table S108. Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 14Q GAIN MUTATED | 11 | 16 | 8 |
| 14Q GAIN WILD-TYPE | 42 | 205 | 169 |
Figure S108. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0335 (Fisher's exact test), Q value = 0.094
Table S109. Gene #26: '14q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 14Q GAIN MUTATED | 0 | 1 | 2 | 0 | 0 | 3 | 2 | 0 | 1 |
| 14Q GAIN WILD-TYPE | 12 | 8 | 6 | 12 | 9 | 4 | 11 | 9 | 5 |
Figure S109. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0387 (Fisher's exact test), Q value = 0.1
Table S110. Gene #27: '15q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| 15Q GAIN MUTATED | 4 | 5 | 0 |
| 15Q GAIN WILD-TYPE | 81 | 140 | 125 |
Figure S110. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0144 (Fisher's exact test), Q value = 0.047
Table S111. Gene #27: '15q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 15Q GAIN MUTATED | 2 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 1 |
| 15Q GAIN WILD-TYPE | 49 | 33 | 35 | 37 | 43 | 86 | 20 | 18 | 25 |
Figure S111. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S112. Gene #28: '16p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 16P GAIN MUTATED | 0 | 8 | 17 | 2 | 14 |
| 16P GAIN WILD-TYPE | 31 | 9 | 32 | 25 | 9 |
Figure S112. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S113. Gene #28: '16p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 16P GAIN MUTATED | 3 | 17 | 21 |
| 16P GAIN WILD-TYPE | 39 | 51 | 16 |
Figure S113. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S114. Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 16P GAIN MUTATED | 15 | 85 | 6 |
| 16P GAIN WILD-TYPE | 38 | 136 | 171 |
Figure S114. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0488 (Fisher's exact test), Q value = 0.12
Table S115. Gene #28: '16p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 16P GAIN MUTATED | 21 | 28 | 15 |
| 16P GAIN WILD-TYPE | 64 | 75 | 91 |
Figure S115. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0393 (Fisher's exact test), Q value = 0.1
Table S116. Gene #28: '16p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| 16P GAIN MUTATED | 27 | 25 | 26 |
| 16P GAIN WILD-TYPE | 58 | 120 | 99 |
Figure S116. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0041 (Fisher's exact test), Q value = 0.017
Table S117. Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 16P GAIN MUTATED | 35 | 12 | 18 | 41 |
| 16P GAIN WILD-TYPE | 92 | 82 | 79 | 90 |
Figure S117. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S118. Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 16P GAIN MUTATED | 25 | 22 | 9 | 50 | 0 |
| 16P GAIN WILD-TYPE | 54 | 86 | 87 | 79 | 37 |
Figure S118. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0175 (Fisher's exact test), Q value = 0.056
Table S119. Gene #28: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 16P GAIN MUTATED | 18 | 14 | 21 | 26 | 19 |
| 16P GAIN WILD-TYPE | 42 | 74 | 50 | 49 | 85 |
Figure S119. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00094 (Fisher's exact test), Q value = 0.0048
Table S120. Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 16P GAIN MUTATED | 18 | 14 | 10 | 0 | 14 | 3 | 10 | 4 | 25 |
| 16P GAIN WILD-TYPE | 61 | 41 | 36 | 17 | 41 | 17 | 16 | 38 | 33 |
Figure S120. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S121. Gene #29: '16q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 16Q GAIN MUTATED | 0 | 6 | 17 | 2 | 13 |
| 16Q GAIN WILD-TYPE | 31 | 11 | 32 | 25 | 10 |
Figure S121. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S122. Gene #29: '16q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 16Q GAIN MUTATED | 2 | 16 | 20 |
| 16Q GAIN WILD-TYPE | 40 | 52 | 17 |
Figure S122. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S123. Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 16Q GAIN MUTATED | 14 | 85 | 5 |
| 16Q GAIN WILD-TYPE | 39 | 136 | 172 |
Figure S123. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0349 (Fisher's exact test), Q value = 0.097
Table S124. Gene #29: '16q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 16Q GAIN MUTATED | 21 | 29 | 15 |
| 16Q GAIN WILD-TYPE | 64 | 74 | 91 |
Figure S124. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0452 (Fisher's exact test), Q value = 0.11
Table S125. Gene #29: '16q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| 16Q GAIN MUTATED | 27 | 26 | 25 |
| 16Q GAIN WILD-TYPE | 58 | 119 | 100 |
Figure S125. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00279 (Fisher's exact test), Q value = 0.012
Table S126. Gene #29: '16q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 16Q GAIN MUTATED | 37 | 12 | 16 | 39 |
| 16Q GAIN WILD-TYPE | 90 | 82 | 81 | 92 |
Figure S126. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S127. Gene #29: '16q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 16Q GAIN MUTATED | 25 | 23 | 9 | 47 | 0 |
| 16Q GAIN WILD-TYPE | 54 | 85 | 87 | 82 | 37 |
Figure S127. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00964 (Fisher's exact test), Q value = 0.034
Table S128. Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 16Q GAIN MUTATED | 18 | 14 | 22 | 25 | 17 |
| 16Q GAIN WILD-TYPE | 42 | 74 | 49 | 50 | 87 |
Figure S128. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00281 (Fisher's exact test), Q value = 0.012
Table S129. Gene #29: '16q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 16Q GAIN MUTATED | 17 | 14 | 11 | 0 | 14 | 3 | 9 | 4 | 24 |
| 16Q GAIN WILD-TYPE | 62 | 41 | 35 | 17 | 41 | 17 | 17 | 38 | 34 |
Figure S129. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0331 (Fisher's exact test), Q value = 0.093
Table S130. Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 17Q GAIN MUTATED | 3 | 11 | 11 |
| 17Q GAIN WILD-TYPE | 39 | 57 | 26 |
Figure S130. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S131. Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 17Q GAIN MUTATED | 10 | 60 | 14 |
| 17Q GAIN WILD-TYPE | 43 | 161 | 163 |
Figure S131. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00191 (Fisher's exact test), Q value = 0.009
Table S132. Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 17Q GAIN MUTATED | 12 | 33 | 15 |
| 17Q GAIN WILD-TYPE | 73 | 70 | 91 |
Figure S132. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S133. Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 17Q GAIN MUTATED | 46 | 9 | 11 | 18 |
| 17Q GAIN WILD-TYPE | 81 | 85 | 86 | 113 |
Figure S133. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 5e-04
Table S134. Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 17Q GAIN MUTATED | 17 | 32 | 6 | 26 | 3 |
| 17Q GAIN WILD-TYPE | 62 | 76 | 90 | 103 | 34 |
Figure S134. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0478 (Fisher's exact test), Q value = 0.12
Table S135. Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 17Q GAIN MUTATED | 16 | 14 | 13 | 20 | 12 |
| 17Q GAIN WILD-TYPE | 44 | 74 | 58 | 55 | 92 |
Figure S135. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0234 (Fisher's exact test), Q value = 0.07
Table S136. Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 17Q GAIN MUTATED | 18 | 10 | 11 | 0 | 16 | 2 | 6 | 2 | 10 |
| 17Q GAIN WILD-TYPE | 61 | 45 | 35 | 17 | 39 | 18 | 20 | 40 | 48 |
Figure S136. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.028 (Fisher's exact test), Q value = 0.081
Table S137. Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 18P GAIN MUTATED | 4 | 2 | 11 |
| 18P GAIN WILD-TYPE | 81 | 101 | 95 |
Figure S137. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.039 (Fisher's exact test), Q value = 0.1
Table S138. Gene #32: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 18P GAIN MUTATED | 2 | 8 | 8 | 5 |
| 18P GAIN WILD-TYPE | 125 | 86 | 89 | 126 |
Figure S138. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00045
Table S139. Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 18P GAIN MUTATED | 3 | 2 | 13 | 1 | 4 |
| 18P GAIN WILD-TYPE | 76 | 106 | 83 | 128 | 33 |
Figure S139. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0135 (Fisher's exact test), Q value = 0.045
Table S140. Gene #32: '18p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 18P GAIN MUTATED | 5 | 6 | 0 | 3 | 3 | 1 | 0 | 4 | 0 |
| 18P GAIN WILD-TYPE | 74 | 49 | 46 | 14 | 52 | 19 | 26 | 38 | 58 |
Figure S140. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0114 (Fisher's exact test), Q value = 0.039
Table S141. Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 18Q GAIN MUTATED | 0 | 3 | 7 | 4 |
| 18Q GAIN WILD-TYPE | 127 | 91 | 90 | 127 |
Figure S141. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00039
Table S142. Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 18Q GAIN MUTATED | 2 | 0 | 8 | 0 | 4 |
| 18Q GAIN WILD-TYPE | 77 | 108 | 88 | 129 | 33 |
Figure S142. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0193 (Fisher's exact test), Q value = 0.061
Table S143. Gene #33: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 18Q GAIN MUTATED | 1 | 5 | 0 | 2 | 2 | 1 | 0 | 3 | 0 |
| 18Q GAIN WILD-TYPE | 78 | 50 | 46 | 15 | 53 | 19 | 26 | 39 | 58 |
Figure S143. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00045
Table S144. Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 19P GAIN MUTATED | 13 | 48 | 12 |
| 19P GAIN WILD-TYPE | 40 | 173 | 165 |
Figure S144. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00074
Table S145. Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 19P GAIN MUTATED | 26 | 18 | 9 | 19 | 1 |
| 19P GAIN WILD-TYPE | 53 | 90 | 87 | 110 | 36 |
Figure S145. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S146. Gene #34: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 19P GAIN MUTATED | 19 | 11 | 17 | 10 | 5 |
| 19P GAIN WILD-TYPE | 41 | 77 | 54 | 65 | 99 |
Figure S146. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0335 (Fisher's exact test), Q value = 0.094
Table S147. Gene #34: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 19P GAIN MUTATED | 12 | 14 | 6 | 0 | 8 | 4 | 8 | 2 | 8 |
| 19P GAIN WILD-TYPE | 67 | 41 | 40 | 17 | 47 | 16 | 18 | 40 | 50 |
Figure S147. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00797 (Fisher's exact test), Q value = 0.029
Table S148. Gene #34: '19p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 19P GAIN MUTATED | 3 | 4 | 5 | 1 | 1 | 0 | 0 | 1 | 1 |
| 19P GAIN WILD-TYPE | 9 | 5 | 3 | 11 | 8 | 7 | 13 | 8 | 5 |
Figure S148. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0452 (Fisher's exact test), Q value = 0.11
Table S149. Gene #35: '19q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 19Q GAIN MUTATED | 0 | 4 | 7 | 5 | 2 |
| 19Q GAIN WILD-TYPE | 31 | 13 | 42 | 22 | 21 |
Figure S149. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0264 (Fisher's exact test), Q value = 0.078
Table S150. Gene #35: '19q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 19Q GAIN MUTATED | 1 | 13 | 4 |
| 19Q GAIN WILD-TYPE | 41 | 55 | 33 |
Figure S150. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00588 (Fisher's exact test), Q value = 0.022
Table S151. Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 19Q GAIN MUTATED | 15 | 48 | 21 |
| 19Q GAIN WILD-TYPE | 38 | 173 | 156 |
Figure S151. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0126 (Fisher's exact test), Q value = 0.043
Table S152. Gene #35: '19q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| 19Q GAIN MUTATED | 23 | 33 | 15 |
| 19Q GAIN WILD-TYPE | 62 | 112 | 110 |
Figure S152. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.001
Table S153. Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 19Q GAIN MUTATED | 28 | 20 | 12 | 23 | 1 |
| 19Q GAIN WILD-TYPE | 51 | 88 | 84 | 106 | 36 |
Figure S153. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00381 (Fisher's exact test), Q value = 0.016
Table S154. Gene #35: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 19Q GAIN MUTATED | 17 | 13 | 21 | 9 | 12 |
| 19Q GAIN WILD-TYPE | 43 | 75 | 50 | 66 | 92 |
Figure S154. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0194 (Fisher's exact test), Q value = 0.061
Table S155. Gene #35: '19q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 19Q GAIN MUTATED | 4 | 7 | 0 | 4 | 0 | 2 |
| 19Q GAIN WILD-TYPE | 14 | 13 | 16 | 7 | 11 | 7 |
Figure S155. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00472 (Fisher's exact test), Q value = 0.018
Table S156. Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 19Q GAIN MUTATED | 4 | 4 | 5 | 1 | 0 | 1 | 0 | 1 | 1 |
| 19Q GAIN WILD-TYPE | 8 | 5 | 3 | 11 | 9 | 6 | 13 | 8 | 5 |
Figure S156. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S157. Gene #36: '20p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 20P GAIN MUTATED | 4 | 11 | 34 | 15 | 19 |
| 20P GAIN WILD-TYPE | 27 | 6 | 15 | 12 | 4 |
Figure S157. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S158. Gene #36: '20p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 20P GAIN MUTATED | 9 | 51 | 23 |
| 20P GAIN WILD-TYPE | 33 | 17 | 14 |
Figure S158. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S159. Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 20P GAIN MUTATED | 52 | 144 | 48 |
| 20P GAIN WILD-TYPE | 1 | 77 | 129 |
Figure S159. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00275 (Fisher's exact test), Q value = 0.012
Table S160. Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 20P GAIN MUTATED | 42 | 69 | 47 |
| 20P GAIN WILD-TYPE | 43 | 34 | 59 |
Figure S160. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.045 (Fisher's exact test), Q value = 0.11
Table S161. Gene #36: '20p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| 20P GAIN MUTATED | 51 | 78 | 54 |
| 20P GAIN WILD-TYPE | 34 | 67 | 71 |
Figure S161. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0016
Table S162. Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 20P GAIN MUTATED | 85 | 36 | 48 | 73 |
| 20P GAIN WILD-TYPE | 42 | 58 | 49 | 58 |
Figure S162. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S163. Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 20P GAIN MUTATED | 48 | 71 | 30 | 88 | 5 |
| 20P GAIN WILD-TYPE | 31 | 37 | 66 | 41 | 32 |
Figure S163. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00077 (Fisher's exact test), Q value = 0.0041
Table S164. Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 20P GAIN MUTATED | 36 | 35 | 44 | 52 | 49 |
| 20P GAIN WILD-TYPE | 24 | 53 | 27 | 23 | 55 |
Figure S164. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S165. Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 20P GAIN MUTATED | 42 | 29 | 31 | 4 | 35 | 11 | 13 | 7 | 44 |
| 20P GAIN WILD-TYPE | 37 | 26 | 15 | 13 | 20 | 9 | 13 | 35 | 14 |
Figure S165. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S166. Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 20Q GAIN MUTATED | 5 | 14 | 48 | 16 | 21 |
| 20Q GAIN WILD-TYPE | 26 | 3 | 1 | 11 | 2 |
Figure S166. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S167. Gene #37: '20q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 20Q GAIN MUTATED | 11 | 58 | 35 |
| 20Q GAIN WILD-TYPE | 31 | 10 | 2 |
Figure S167. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S168. Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 20Q GAIN MUTATED | 53 | 210 | 58 |
| 20Q GAIN WILD-TYPE | 0 | 11 | 119 |
Figure S168. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S169. Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 20Q GAIN MUTATED | 52 | 100 | 59 |
| 20Q GAIN WILD-TYPE | 33 | 3 | 47 |
Figure S169. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00821 (Fisher's exact test), Q value = 0.029
Table S170. Gene #37: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| 20Q GAIN MUTATED | 67 | 106 | 75 |
| 20Q GAIN WILD-TYPE | 18 | 39 | 50 |
Figure S170. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S171. Gene #37: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 20Q GAIN MUTATED | 46 | 20 | 29 | 25 | 31 | 47 | 11 | 16 | 23 |
| 20Q GAIN WILD-TYPE | 5 | 13 | 6 | 14 | 12 | 39 | 11 | 4 | 3 |
Figure S171. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S172. Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 20Q GAIN MUTATED | 122 | 41 | 67 | 89 |
| 20Q GAIN WILD-TYPE | 5 | 53 | 30 | 42 |
Figure S172. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S173. Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 20Q GAIN MUTATED | 73 | 95 | 34 | 111 | 6 |
| 20Q GAIN WILD-TYPE | 6 | 13 | 62 | 18 | 31 |
Figure S173. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S174. Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 20Q GAIN MUTATED | 54 | 45 | 57 | 69 | 58 |
| 20Q GAIN WILD-TYPE | 6 | 43 | 14 | 6 | 46 |
Figure S174. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S175. Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 20Q GAIN MUTATED | 59 | 40 | 42 | 4 | 44 | 13 | 16 | 12 | 53 |
| 20Q GAIN WILD-TYPE | 20 | 15 | 4 | 13 | 11 | 7 | 10 | 30 | 5 |
Figure S175. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S176. Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 20Q GAIN MUTATED | 17 | 18 | 9 | 11 | 3 | 9 |
| 20Q GAIN WILD-TYPE | 1 | 2 | 7 | 0 | 8 | 0 |
Figure S176. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0485 (Fisher's exact test), Q value = 0.12
Table S177. Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 20Q GAIN MUTATED | 12 | 7 | 8 | 8 | 6 | 5 | 7 | 8 | 6 |
| 20Q GAIN WILD-TYPE | 0 | 2 | 0 | 4 | 3 | 2 | 6 | 1 | 0 |
Figure S177. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0441 (Fisher's exact test), Q value = 0.11
Table S178. Gene #38: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 21Q GAIN MUTATED | 3 | 17 | 4 |
| 21Q GAIN WILD-TYPE | 50 | 204 | 173 |
Figure S178. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0441 (Fisher's exact test), Q value = 0.11
Table S179. Gene #38: '21q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 21Q GAIN MUTATED | 1 | 9 | 9 |
| 21Q GAIN WILD-TYPE | 84 | 94 | 97 |
Figure S179. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0364 (Fisher's exact test), Q value = 0.1
Table S180. Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 22Q GAIN MUTATED | 1 | 10 | 1 |
| 22Q GAIN WILD-TYPE | 52 | 211 | 176 |
Figure S180. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00228 (Fisher's exact test), Q value = 0.01
Table S181. Gene #40: 'xp gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| XP GAIN MUTATED | 1 | 2 | 9 | 9 | 0 |
| XP GAIN WILD-TYPE | 30 | 15 | 40 | 18 | 23 |
Figure S181. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00096 (Fisher's exact test), Q value = 0.0049
Table S182. Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| XP GAIN MUTATED | 13 | 41 | 14 |
| XP GAIN WILD-TYPE | 40 | 180 | 163 |
Figure S182. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00345 (Fisher's exact test), Q value = 0.015
Table S183. Gene #40: 'xp gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| XP GAIN MUTATED | 14 | 35 | 11 |
| XP GAIN WILD-TYPE | 71 | 110 | 114 |
Figure S183. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0361 (Fisher's exact test), Q value = 0.1
Table S184. Gene #40: 'xp gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| XP GAIN MUTATED | 11 | 25 | 7 | 19 | 5 |
| XP GAIN WILD-TYPE | 68 | 83 | 89 | 110 | 32 |
Figure S184. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0109 (Fisher's exact test), Q value = 0.038
Table S185. Gene #41: 'xq gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| XQ GAIN MUTATED | 1 | 2 | 9 | 9 | 1 |
| XQ GAIN WILD-TYPE | 30 | 15 | 40 | 18 | 22 |
Figure S185. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00093 (Fisher's exact test), Q value = 0.0048
Table S186. Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| XQ GAIN MUTATED | 16 | 45 | 18 |
| XQ GAIN WILD-TYPE | 37 | 176 | 159 |
Figure S186. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00141 (Fisher's exact test), Q value = 0.0069
Table S187. Gene #41: 'xq gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| XQ GAIN MUTATED | 18 | 38 | 12 |
| XQ GAIN WILD-TYPE | 67 | 107 | 113 |
Figure S187. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0289 (Fisher's exact test), Q value = 0.084
Table S188. Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 1P LOSS MUTATED | 2 | 6 | 12 | 2 | 6 |
| 1P LOSS WILD-TYPE | 29 | 11 | 37 | 25 | 17 |
Figure S188. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S189. Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 1P LOSS MUTATED | 16 | 70 | 6 |
| 1P LOSS WILD-TYPE | 37 | 151 | 171 |
Figure S189. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00701 (Fisher's exact test), Q value = 0.026
Table S190. Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 1P LOSS MUTATED | 14 | 32 | 15 |
| 1P LOSS WILD-TYPE | 71 | 71 | 91 |
Figure S190. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S191. Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 1P LOSS MUTATED | 38 | 6 | 23 | 24 |
| 1P LOSS WILD-TYPE | 89 | 88 | 74 | 107 |
Figure S191. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00045
Table S192. Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 1P LOSS MUTATED | 29 | 23 | 8 | 28 | 3 |
| 1P LOSS WILD-TYPE | 50 | 85 | 88 | 101 | 34 |
Figure S192. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00157 (Fisher's exact test), Q value = 0.0075
Table S193. Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 1P LOSS MUTATED | 20 | 12 | 18 | 19 | 11 |
| 1P LOSS WILD-TYPE | 40 | 76 | 53 | 56 | 93 |
Figure S193. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00302 (Fisher's exact test), Q value = 0.013
Table S194. Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 1P LOSS MUTATED | 19 | 11 | 18 | 0 | 14 | 2 | 2 | 4 | 10 |
| 1P LOSS WILD-TYPE | 60 | 44 | 28 | 17 | 41 | 18 | 24 | 38 | 48 |
Figure S194. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S195. Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 1Q LOSS MUTATED | 8 | 42 | 4 |
| 1Q LOSS WILD-TYPE | 45 | 179 | 173 |
Figure S195. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00309 (Fisher's exact test), Q value = 0.013
Table S196. Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 1Q LOSS MUTATED | 23 | 3 | 14 | 13 |
| 1Q LOSS WILD-TYPE | 104 | 91 | 83 | 118 |
Figure S196. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0102 (Fisher's exact test), Q value = 0.036
Table S197. Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 1Q LOSS MUTATED | 16 | 15 | 4 | 16 | 2 |
| 1Q LOSS WILD-TYPE | 63 | 93 | 92 | 113 | 35 |
Figure S197. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0162 (Fisher's exact test), Q value = 0.052
Table S198. Gene #43: '1q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 1Q LOSS MUTATED | 11 | 8 | 11 | 0 | 10 | 0 | 1 | 3 | 3 |
| 1Q LOSS WILD-TYPE | 68 | 47 | 35 | 17 | 45 | 20 | 25 | 39 | 55 |
Figure S198. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.049 (Fisher's exact test), Q value = 0.12
Table S199. Gene #44: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 2P LOSS MUTATED | 2 | 4 | 0 |
| 2P LOSS WILD-TYPE | 51 | 217 | 177 |
Figure S199. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.0011
Table S200. Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 3P LOSS MUTATED | 10 | 36 | 8 |
| 3P LOSS WILD-TYPE | 43 | 185 | 169 |
Figure S200. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0393 (Fisher's exact test), Q value = 0.1
Table S201. Gene #46: '3p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 3P LOSS MUTATED | 20 | 4 | 13 | 17 |
| 3P LOSS WILD-TYPE | 107 | 90 | 84 | 114 |
Figure S201. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0303 (Fisher's exact test), Q value = 0.087
Table S202. Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 3P LOSS MUTATED | 2 | 4 | 1 | 5 | 0 | 0 |
| 3P LOSS WILD-TYPE | 16 | 16 | 15 | 6 | 11 | 9 |
Figure S202. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0037
Table S203. Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 3Q LOSS MUTATED | 9 | 21 | 5 |
| 3Q LOSS WILD-TYPE | 44 | 200 | 172 |
Figure S203. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S204. Gene #48: '4p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 4P LOSS MUTATED | 3 | 8 | 21 | 2 | 13 |
| 4P LOSS WILD-TYPE | 28 | 9 | 28 | 25 | 10 |
Figure S204. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00182 (Fisher's exact test), Q value = 0.0086
Table S205. Gene #48: '4p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 4P LOSS MUTATED | 6 | 22 | 19 |
| 4P LOSS WILD-TYPE | 36 | 46 | 18 |
Figure S205. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S206. Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 4P LOSS MUTATED | 30 | 99 | 10 |
| 4P LOSS WILD-TYPE | 23 | 122 | 167 |
Figure S206. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00802 (Fisher's exact test), Q value = 0.029
Table S207. Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 4P LOSS MUTATED | 21 | 43 | 25 |
| 4P LOSS WILD-TYPE | 64 | 60 | 81 |
Figure S207. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0357 (Fisher's exact test), Q value = 0.099
Table S208. Gene #48: '4p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 4P LOSS MUTATED | 16 | 7 | 13 | 13 | 17 | 17 | 7 | 1 | 10 |
| 4P LOSS WILD-TYPE | 35 | 26 | 22 | 26 | 26 | 69 | 15 | 19 | 16 |
Figure S208. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S209. Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 4P LOSS MUTATED | 59 | 11 | 29 | 39 |
| 4P LOSS WILD-TYPE | 68 | 83 | 68 | 92 |
Figure S209. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S210. Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 4P LOSS MUTATED | 35 | 42 | 8 | 50 | 3 |
| 4P LOSS WILD-TYPE | 44 | 66 | 88 | 79 | 34 |
Figure S210. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00015 (Fisher's exact test), Q value = 0.001
Table S211. Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 4P LOSS MUTATED | 27 | 17 | 21 | 33 | 20 |
| 4P LOSS WILD-TYPE | 33 | 71 | 50 | 42 | 84 |
Figure S211. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0221 (Fisher's exact test), Q value = 0.068
Table S212. Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 4P LOSS MUTATED | 25 | 13 | 16 | 1 | 16 | 6 | 7 | 7 | 27 |
| 4P LOSS WILD-TYPE | 54 | 42 | 30 | 16 | 39 | 14 | 19 | 35 | 31 |
Figure S212. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0139 (Fisher's exact test), Q value = 0.046
Table S213. Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 4P LOSS MUTATED | 10 | 8 | 3 | 2 | 0 | 4 |
| 4P LOSS WILD-TYPE | 8 | 12 | 13 | 9 | 11 | 5 |
Figure S213. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00094
Table S214. Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 4Q LOSS MUTATED | 3 | 5 | 22 | 2 | 11 |
| 4Q LOSS WILD-TYPE | 28 | 12 | 27 | 25 | 12 |
Figure S214. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00699 (Fisher's exact test), Q value = 0.026
Table S215. Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 4Q LOSS MUTATED | 5 | 23 | 15 |
| 4Q LOSS WILD-TYPE | 37 | 45 | 22 |
Figure S215. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S216. Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 4Q LOSS MUTATED | 25 | 92 | 10 |
| 4Q LOSS WILD-TYPE | 28 | 129 | 167 |
Figure S216. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.027 (Fisher's exact test), Q value = 0.079
Table S217. Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 4Q LOSS MUTATED | 21 | 38 | 22 |
| 4Q LOSS WILD-TYPE | 64 | 65 | 84 |
Figure S217. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S218. Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 4Q LOSS MUTATED | 54 | 9 | 25 | 38 |
| 4Q LOSS WILD-TYPE | 73 | 85 | 72 | 93 |
Figure S218. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S219. Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 4Q LOSS MUTATED | 34 | 38 | 5 | 46 | 3 |
| 4Q LOSS WILD-TYPE | 45 | 70 | 91 | 83 | 34 |
Figure S219. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00028 (Fisher's exact test), Q value = 0.0016
Table S220. Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 4Q LOSS MUTATED | 25 | 14 | 19 | 29 | 19 |
| 4Q LOSS WILD-TYPE | 35 | 74 | 52 | 46 | 85 |
Figure S220. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0351 (Fisher's exact test), Q value = 0.097
Table S221. Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 4Q LOSS MUTATED | 20 | 13 | 16 | 1 | 17 | 4 | 4 | 7 | 24 |
| 4Q LOSS WILD-TYPE | 59 | 42 | 30 | 16 | 38 | 16 | 22 | 35 | 34 |
Figure S221. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S222. Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 5P LOSS MUTATED | 11 | 44 | 5 |
| 5P LOSS WILD-TYPE | 42 | 177 | 172 |
Figure S222. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0024 (Fisher's exact test), Q value = 0.011
Table S223. Gene #50: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 5P LOSS MUTATED | 11 | 24 | 7 |
| 5P LOSS WILD-TYPE | 74 | 79 | 99 |
Figure S223. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00054 (Fisher's exact test), Q value = 0.003
Table S224. Gene #50: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 5P LOSS MUTATED | 12 | 22 | 2 | 20 | 4 |
| 5P LOSS WILD-TYPE | 67 | 86 | 94 | 109 | 33 |
Figure S224. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0434 (Fisher's exact test), Q value = 0.11
Table S225. Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 5P LOSS MUTATED | 15 | 7 | 8 | 9 | 10 |
| 5P LOSS WILD-TYPE | 45 | 81 | 63 | 66 | 94 |
Figure S225. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0173 (Fisher's exact test), Q value = 0.055
Table S226. Gene #51: '5q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 5Q LOSS MUTATED | 2 | 6 | 9 | 1 | 6 |
| 5Q LOSS WILD-TYPE | 29 | 11 | 40 | 26 | 17 |
Figure S226. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S227. Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 5Q LOSS MUTATED | 14 | 59 | 7 |
| 5Q LOSS WILD-TYPE | 39 | 162 | 170 |
Figure S227. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.028 (Fisher's exact test), Q value = 0.081
Table S228. Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 5Q LOSS MUTATED | 18 | 26 | 12 |
| 5Q LOSS WILD-TYPE | 67 | 77 | 94 |
Figure S228. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.001
Table S229. Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 5Q LOSS MUTATED | 34 | 5 | 20 | 21 |
| 5Q LOSS WILD-TYPE | 93 | 89 | 77 | 110 |
Figure S229. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.0014
Table S230. Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 5Q LOSS MUTATED | 20 | 26 | 5 | 26 | 3 |
| 5Q LOSS WILD-TYPE | 59 | 82 | 91 | 103 | 34 |
Figure S230. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00414 (Fisher's exact test), Q value = 0.017
Table S231. Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 5Q LOSS MUTATED | 20 | 9 | 13 | 14 | 12 |
| 5Q LOSS WILD-TYPE | 40 | 79 | 58 | 61 | 92 |
Figure S231. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0254 (Fisher's exact test), Q value = 0.076
Table S232. Gene #53: '6q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 6Q LOSS MUTATED | 2 | 1 | 0 | 3 | 0 | 3 |
| 6Q LOSS WILD-TYPE | 16 | 19 | 16 | 8 | 11 | 6 |
Figure S232. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0375 (Fisher's exact test), Q value = 0.1
Table S233. Gene #54: '7q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 7Q LOSS MUTATED | 2 | 2 | 0 |
| 7Q LOSS WILD-TYPE | 51 | 219 | 177 |
Figure S233. Get High-res Image Gene #54: '7q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0211 (Fisher's exact test), Q value = 0.065
Table S234. Gene #54: '7q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 7Q LOSS MUTATED | 0 | 4 | 0 |
| 7Q LOSS WILD-TYPE | 85 | 99 | 106 |
Figure S234. Get High-res Image Gene #54: '7q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00244 (Fisher's exact test), Q value = 0.011
Table S235. Gene #55: '8p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 8P LOSS MUTATED | 2 | 8 | 20 | 6 | 9 |
| 8P LOSS WILD-TYPE | 29 | 9 | 29 | 21 | 14 |
Figure S235. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00441 (Fisher's exact test), Q value = 0.018
Table S236. Gene #55: '8p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 8P LOSS MUTATED | 5 | 25 | 15 |
| 8P LOSS WILD-TYPE | 37 | 43 | 22 |
Figure S236. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S237. Gene #55: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 8P LOSS MUTATED | 9 | 117 | 12 |
| 8P LOSS WILD-TYPE | 44 | 104 | 165 |
Figure S237. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0182 (Fisher's exact test), Q value = 0.058
Table S238. Gene #55: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 8P LOSS MUTATED | 23 | 43 | 26 |
| 8P LOSS WILD-TYPE | 62 | 60 | 80 |
Figure S238. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0149 (Fisher's exact test), Q value = 0.048
Table S239. Gene #55: '8p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 8P LOSS MUTATED | 25 | 6 | 13 | 12 | 14 | 16 | 4 | 6 | 9 |
| 8P LOSS WILD-TYPE | 26 | 27 | 22 | 27 | 29 | 70 | 18 | 14 | 17 |
Figure S239. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00112 (Fisher's exact test), Q value = 0.0056
Table S240. Gene #55: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 8P LOSS MUTATED | 51 | 15 | 29 | 43 |
| 8P LOSS WILD-TYPE | 76 | 79 | 68 | 88 |
Figure S240. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S241. Gene #55: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 8P LOSS MUTATED | 36 | 34 | 14 | 51 | 3 |
| 8P LOSS WILD-TYPE | 43 | 74 | 82 | 78 | 34 |
Figure S241. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00033 (Fisher's exact test), Q value = 0.0019
Table S242. Gene #55: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 8P LOSS MUTATED | 29 | 13 | 23 | 26 | 29 |
| 8P LOSS WILD-TYPE | 31 | 75 | 48 | 49 | 75 |
Figure S242. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0446 (Fisher's exact test), Q value = 0.11
Table S243. Gene #55: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 8P LOSS MUTATED | 26 | 16 | 15 | 1 | 22 | 4 | 6 | 7 | 23 |
| 8P LOSS WILD-TYPE | 53 | 39 | 31 | 16 | 33 | 16 | 20 | 35 | 35 |
Figure S243. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.036
Table S244. Gene #55: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 8P LOSS MUTATED | 8 | 7 | 2 | 4 | 1 | 7 |
| 8P LOSS WILD-TYPE | 10 | 13 | 14 | 7 | 10 | 2 |
Figure S244. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 7e-04
Table S245. Gene #56: '8q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 8Q LOSS MUTATED | 4 | 21 | 1 |
| 8Q LOSS WILD-TYPE | 49 | 200 | 176 |
Figure S245. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00289 (Fisher's exact test), Q value = 0.013
Table S246. Gene #56: '8q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 8Q LOSS MUTATED | 1 | 3 | 1 | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 17 | 17 | 15 | 11 | 11 | 4 |
Figure S246. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00601 (Fisher's exact test), Q value = 0.023
Table S247. Gene #56: '8q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 8Q LOSS MUTATED | 6 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 |
| 8Q LOSS WILD-TYPE | 6 | 9 | 8 | 12 | 8 | 6 | 12 | 9 | 5 |
Figure S247. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0313 (Fisher's exact test), Q value = 0.089
Table S248. Gene #57: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 9P LOSS MUTATED | 0 | 4 | 7 | 1 | 3 |
| 9P LOSS WILD-TYPE | 31 | 13 | 42 | 26 | 20 |
Figure S248. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.012 (Fisher's exact test), Q value = 0.041
Table S249. Gene #57: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 9P LOSS MUTATED | 0 | 9 | 6 |
| 9P LOSS WILD-TYPE | 42 | 59 | 31 |
Figure S249. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S250. Gene #57: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 9P LOSS MUTATED | 7 | 41 | 6 |
| 9P LOSS WILD-TYPE | 46 | 180 | 171 |
Figure S250. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0131 (Fisher's exact test), Q value = 0.044
Table S251. Gene #57: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 9P LOSS MUTATED | 11 | 21 | 7 |
| 9P LOSS WILD-TYPE | 74 | 82 | 99 |
Figure S251. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 5e-04
Table S252. Gene #57: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 9P LOSS MUTATED | 26 | 2 | 15 | 11 |
| 9P LOSS WILD-TYPE | 101 | 92 | 82 | 120 |
Figure S252. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00044 (Fisher's exact test), Q value = 0.0025
Table S253. Gene #57: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 9P LOSS MUTATED | 16 | 18 | 4 | 16 | 0 |
| 9P LOSS WILD-TYPE | 63 | 90 | 92 | 113 | 37 |
Figure S253. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00461 (Fisher's exact test), Q value = 0.018
Table S254. Gene #57: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 9P LOSS MUTATED | 9 | 6 | 10 | 16 | 5 |
| 9P LOSS WILD-TYPE | 51 | 82 | 61 | 59 | 99 |
Figure S254. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.002 (Fisher's exact test), Q value = 0.0093
Table S255. Gene #58: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 9Q LOSS MUTATED | 0 | 5 | 6 | 0 | 4 |
| 9Q LOSS WILD-TYPE | 31 | 12 | 43 | 27 | 19 |
Figure S255. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0487 (Fisher's exact test), Q value = 0.12
Table S256. Gene #58: '9q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 9Q LOSS MUTATED | 1 | 7 | 7 |
| 9Q LOSS WILD-TYPE | 41 | 61 | 30 |
Figure S256. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S257. Gene #58: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 9Q LOSS MUTATED | 7 | 42 | 5 |
| 9Q LOSS WILD-TYPE | 46 | 179 | 172 |
Figure S257. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00325 (Fisher's exact test), Q value = 0.014
Table S258. Gene #58: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 9Q LOSS MUTATED | 11 | 22 | 6 |
| 9Q LOSS WILD-TYPE | 74 | 81 | 100 |
Figure S258. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 5e-04
Table S259. Gene #58: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 9Q LOSS MUTATED | 25 | 2 | 16 | 11 |
| 9Q LOSS WILD-TYPE | 102 | 92 | 81 | 120 |
Figure S259. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00097 (Fisher's exact test), Q value = 0.0049
Table S260. Gene #58: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 9Q LOSS MUTATED | 18 | 16 | 4 | 15 | 1 |
| 9Q LOSS WILD-TYPE | 61 | 92 | 92 | 114 | 36 |
Figure S260. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00699 (Fisher's exact test), Q value = 0.026
Table S261. Gene #58: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 9Q LOSS MUTATED | 8 | 5 | 12 | 15 | 6 |
| 9Q LOSS WILD-TYPE | 52 | 83 | 59 | 60 | 98 |
Figure S261. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.041 (Fisher's exact test), Q value = 0.11
Table S262. Gene #58: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 9Q LOSS MUTATED | 5 | 3 | 1 | 5 | 0 | 3 |
| 9Q LOSS WILD-TYPE | 13 | 17 | 15 | 6 | 11 | 6 |
Figure S262. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00086 (Fisher's exact test), Q value = 0.0045
Table S263. Gene #59: '10p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 10P LOSS MUTATED | 0 | 3 | 6 | 0 | 7 |
| 10P LOSS WILD-TYPE | 31 | 14 | 43 | 27 | 16 |
Figure S263. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S264. Gene #59: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 10P LOSS MUTATED | 13 | 51 | 4 |
| 10P LOSS WILD-TYPE | 40 | 170 | 173 |
Figure S264. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.0085
Table S265. Gene #59: '10p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 10P LOSS MUTATED | 11 | 29 | 11 |
| 10P LOSS WILD-TYPE | 74 | 74 | 95 |
Figure S265. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.001
Table S266. Gene #59: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 10P LOSS MUTATED | 32 | 4 | 15 | 16 |
| 10P LOSS WILD-TYPE | 95 | 90 | 82 | 115 |
Figure S266. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 7e-04
Table S267. Gene #59: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 10P LOSS MUTATED | 22 | 18 | 7 | 20 | 0 |
| 10P LOSS WILD-TYPE | 57 | 90 | 89 | 109 | 37 |
Figure S267. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0275 (Fisher's exact test), Q value = 0.08
Table S268. Gene #59: '10p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 10P LOSS MUTATED | 4 | 1 | 4 | 0 | 2 | 1 | 0 | 2 | 0 |
| 10P LOSS WILD-TYPE | 8 | 8 | 4 | 12 | 7 | 6 | 13 | 7 | 6 |
Figure S268. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00039 (Fisher's exact test), Q value = 0.0022
Table S269. Gene #60: '10q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 10Q LOSS MUTATED | 0 | 4 | 8 | 0 | 7 |
| 10Q LOSS WILD-TYPE | 31 | 13 | 41 | 27 | 16 |
Figure S269. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.022 (Fisher's exact test), Q value = 0.068
Table S270. Gene #60: '10q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 10Q LOSS MUTATED | 1 | 10 | 8 |
| 10Q LOSS WILD-TYPE | 41 | 58 | 29 |
Figure S270. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S271. Gene #60: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 10Q LOSS MUTATED | 11 | 58 | 4 |
| 10Q LOSS WILD-TYPE | 42 | 163 | 173 |
Figure S271. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00197 (Fisher's exact test), Q value = 0.0093
Table S272. Gene #60: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 10Q LOSS MUTATED | 11 | 30 | 12 |
| 10Q LOSS WILD-TYPE | 74 | 73 | 94 |
Figure S272. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 5e-04
Table S273. Gene #60: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 10Q LOSS MUTATED | 34 | 4 | 15 | 19 |
| 10Q LOSS WILD-TYPE | 93 | 90 | 82 | 112 |
Figure S273. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S274. Gene #60: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 10Q LOSS MUTATED | 24 | 19 | 5 | 24 | 0 |
| 10Q LOSS WILD-TYPE | 55 | 89 | 91 | 105 | 37 |
Figure S274. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0271 (Fisher's exact test), Q value = 0.079
Table S275. Gene #61: '11p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 11P LOSS MUTATED | 1 | 13 | 4 |
| 11P LOSS WILD-TYPE | 41 | 55 | 33 |
Figure S275. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00645 (Fisher's exact test), Q value = 0.024
Table S276. Gene #61: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 11P LOSS MUTATED | 9 | 32 | 10 |
| 11P LOSS WILD-TYPE | 44 | 189 | 167 |
Figure S276. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0436 (Fisher's exact test), Q value = 0.11
Table S277. Gene #61: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 11P LOSS MUTATED | 10 | 16 | 5 | 19 | 1 |
| 11P LOSS WILD-TYPE | 69 | 92 | 91 | 110 | 36 |
Figure S277. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00093 (Fisher's exact test), Q value = 0.0048
Table S278. Gene #61: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 11P LOSS MUTATED | 13 | 6 | 8 | 14 | 4 |
| 11P LOSS WILD-TYPE | 47 | 82 | 63 | 61 | 100 |
Figure S278. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00522 (Fisher's exact test), Q value = 0.02
Table S279. Gene #62: '11q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 11Q LOSS MUTATED | 0 | 4 | 11 | 1 | 4 |
| 11Q LOSS WILD-TYPE | 31 | 13 | 38 | 26 | 19 |
Figure S279. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00055 (Fisher's exact test), Q value = 0.0031
Table S280. Gene #62: '11q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 11Q LOSS MUTATED | 0 | 16 | 4 |
| 11Q LOSS WILD-TYPE | 42 | 52 | 33 |
Figure S280. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00057
Table S281. Gene #62: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 11Q LOSS MUTATED | 9 | 44 | 10 |
| 11Q LOSS WILD-TYPE | 44 | 177 | 167 |
Figure S281. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00201 (Fisher's exact test), Q value = 0.0093
Table S282. Gene #62: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 11Q LOSS MUTATED | 16 | 16 | 7 | 24 | 0 |
| 11Q LOSS WILD-TYPE | 63 | 92 | 89 | 105 | 37 |
Figure S282. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00023 (Fisher's exact test), Q value = 0.0014
Table S283. Gene #62: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 11Q LOSS MUTATED | 16 | 8 | 10 | 17 | 5 |
| 11Q LOSS WILD-TYPE | 44 | 80 | 61 | 58 | 99 |
Figure S283. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00062 (Fisher's exact test), Q value = 0.0034
Table S284. Gene #63: '12p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 12P LOSS MUTATED | 0 | 6 | 6 | 0 | 3 |
| 12P LOSS WILD-TYPE | 31 | 11 | 43 | 27 | 20 |
Figure S284. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0156 (Fisher's exact test), Q value = 0.05
Table S285. Gene #63: '12p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 12P LOSS MUTATED | 0 | 10 | 5 |
| 12P LOSS WILD-TYPE | 42 | 58 | 32 |
Figure S285. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S286. Gene #63: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 12P LOSS MUTATED | 7 | 40 | 1 |
| 12P LOSS WILD-TYPE | 46 | 181 | 176 |
Figure S286. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00379 (Fisher's exact test), Q value = 0.016
Table S287. Gene #63: '12p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 12P LOSS MUTATED | 6 | 21 | 7 |
| 12P LOSS WILD-TYPE | 79 | 82 | 99 |
Figure S287. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00333 (Fisher's exact test), Q value = 0.014
Table S288. Gene #63: '12p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 12P LOSS MUTATED | 21 | 2 | 10 | 15 |
| 12P LOSS WILD-TYPE | 106 | 92 | 87 | 116 |
Figure S288. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S289. Gene #63: '12p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 12P LOSS MUTATED | 15 | 13 | 1 | 19 | 0 |
| 12P LOSS WILD-TYPE | 64 | 95 | 95 | 110 | 37 |
Figure S289. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.015 (Fisher's exact test), Q value = 0.049
Table S290. Gene #63: '12p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 12P LOSS MUTATED | 9 | 4 | 10 | 13 | 6 |
| 12P LOSS WILD-TYPE | 51 | 84 | 61 | 62 | 98 |
Figure S290. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00074 (Fisher's exact test), Q value = 0.004
Table S291. Gene #64: '12q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 12Q LOSS MUTATED | 0 | 6 | 5 | 0 | 3 |
| 12Q LOSS WILD-TYPE | 31 | 11 | 44 | 27 | 20 |
Figure S291. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0212 (Fisher's exact test), Q value = 0.065
Table S292. Gene #64: '12q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 12Q LOSS MUTATED | 0 | 9 | 5 |
| 12Q LOSS WILD-TYPE | 42 | 59 | 32 |
Figure S292. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S293. Gene #64: '12q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 12Q LOSS MUTATED | 8 | 40 | 2 |
| 12Q LOSS WILD-TYPE | 45 | 181 | 175 |
Figure S293. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0142 (Fisher's exact test), Q value = 0.046
Table S294. Gene #64: '12q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 12Q LOSS MUTATED | 8 | 21 | 8 |
| 12Q LOSS WILD-TYPE | 77 | 82 | 98 |
Figure S294. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00105 (Fisher's exact test), Q value = 0.0053
Table S295. Gene #64: '12q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 12Q LOSS MUTATED | 23 | 2 | 10 | 15 |
| 12Q LOSS WILD-TYPE | 104 | 92 | 87 | 116 |
Figure S295. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00074
Table S296. Gene #64: '12q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 12Q LOSS MUTATED | 15 | 14 | 2 | 19 | 0 |
| 12Q LOSS WILD-TYPE | 64 | 94 | 94 | 110 | 37 |
Figure S296. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00443 (Fisher's exact test), Q value = 0.018
Table S297. Gene #64: '12q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 12Q LOSS MUTATED | 11 | 5 | 11 | 13 | 5 |
| 12Q LOSS WILD-TYPE | 49 | 83 | 60 | 62 | 99 |
Figure S297. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0109 (Fisher's exact test), Q value = 0.038
Table S298. Gene #65: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 13Q LOSS MUTATED | 5 | 5 | 2 |
| 13Q LOSS WILD-TYPE | 48 | 216 | 175 |
Figure S298. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0261 (Fisher's exact test), Q value = 0.077
Table S299. Gene #65: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 13Q LOSS MUTATED | 5 | 4 | 0 |
| 13Q LOSS WILD-TYPE | 80 | 99 | 106 |
Figure S299. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S300. Gene #66: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 14Q LOSS MUTATED | 1 | 8 | 29 | 3 | 9 |
| 14Q LOSS WILD-TYPE | 30 | 9 | 20 | 24 | 14 |
Figure S300. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S301. Gene #66: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 14Q LOSS MUTATED | 3 | 28 | 19 |
| 14Q LOSS WILD-TYPE | 39 | 40 | 18 |
Figure S301. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S302. Gene #66: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 14Q LOSS MUTATED | 15 | 118 | 6 |
| 14Q LOSS WILD-TYPE | 38 | 103 | 171 |
Figure S302. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S303. Gene #66: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 14Q LOSS MUTATED | 18 | 49 | 20 |
| 14Q LOSS WILD-TYPE | 67 | 54 | 86 |
Figure S303. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S304. Gene #66: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 14Q LOSS MUTATED | 64 | 9 | 23 | 43 |
| 14Q LOSS WILD-TYPE | 63 | 85 | 74 | 88 |
Figure S304. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S305. Gene #66: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 14Q LOSS MUTATED | 33 | 45 | 4 | 55 | 2 |
| 14Q LOSS WILD-TYPE | 46 | 63 | 92 | 74 | 35 |
Figure S305. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S306. Gene #66: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 14Q LOSS MUTATED | 25 | 12 | 24 | 39 | 19 |
| 14Q LOSS WILD-TYPE | 35 | 76 | 47 | 36 | 85 |
Figure S306. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S307. Gene #66: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 14Q LOSS MUTATED | 29 | 11 | 25 | 0 | 12 | 5 | 6 | 3 | 28 |
| 14Q LOSS WILD-TYPE | 50 | 44 | 21 | 17 | 43 | 15 | 20 | 39 | 30 |
Figure S307. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00375 (Fisher's exact test), Q value = 0.016
Table S308. Gene #66: '14q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 14Q LOSS MUTATED | 9 | 3 | 5 | 5 | 0 | 6 |
| 14Q LOSS WILD-TYPE | 9 | 17 | 11 | 6 | 11 | 3 |
Figure S308. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S309. Gene #67: '15q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 15Q LOSS MUTATED | 2 | 10 | 23 | 5 | 13 |
| 15Q LOSS WILD-TYPE | 29 | 7 | 26 | 22 | 10 |
Figure S309. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00128 (Fisher's exact test), Q value = 0.0063
Table S310. Gene #67: '15q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 15Q LOSS MUTATED | 6 | 29 | 18 |
| 15Q LOSS WILD-TYPE | 36 | 39 | 19 |
Figure S310. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S311. Gene #67: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 15Q LOSS MUTATED | 28 | 117 | 13 |
| 15Q LOSS WILD-TYPE | 25 | 104 | 164 |
Figure S311. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0019
Table S312. Gene #67: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 15Q LOSS MUTATED | 25 | 52 | 27 |
| 15Q LOSS WILD-TYPE | 60 | 51 | 79 |
Figure S312. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S313. Gene #67: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 15Q LOSS MUTATED | 61 | 14 | 33 | 49 |
| 15Q LOSS WILD-TYPE | 66 | 80 | 64 | 82 |
Figure S313. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S314. Gene #67: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 15Q LOSS MUTATED | 40 | 45 | 10 | 58 | 4 |
| 15Q LOSS WILD-TYPE | 39 | 63 | 86 | 71 | 33 |
Figure S314. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S315. Gene #67: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 15Q LOSS MUTATED | 28 | 15 | 36 | 33 | 26 |
| 15Q LOSS WILD-TYPE | 32 | 73 | 35 | 42 | 78 |
Figure S315. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00141 (Fisher's exact test), Q value = 0.0069
Table S316. Gene #67: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 15Q LOSS MUTATED | 33 | 20 | 16 | 0 | 21 | 4 | 8 | 8 | 28 |
| 15Q LOSS WILD-TYPE | 46 | 35 | 30 | 17 | 34 | 16 | 18 | 34 | 30 |
Figure S316. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0422 (Fisher's exact test), Q value = 0.11
Table S317. Gene #67: '15q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 15Q LOSS MUTATED | 9 | 9 | 7 | 7 | 1 | 7 |
| 15Q LOSS WILD-TYPE | 9 | 11 | 9 | 4 | 10 | 2 |
Figure S317. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S318. Gene #70: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 17P LOSS MUTATED | 3 | 11 | 38 | 10 | 16 |
| 17P LOSS WILD-TYPE | 28 | 6 | 11 | 17 | 7 |
Figure S318. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S319. Gene #70: '17p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 17P LOSS MUTATED | 7 | 45 | 26 |
| 17P LOSS WILD-TYPE | 35 | 23 | 11 |
Figure S319. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S320. Gene #70: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 17P LOSS MUTATED | 27 | 182 | 27 |
| 17P LOSS WILD-TYPE | 26 | 39 | 150 |
Figure S320. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S321. Gene #70: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 17P LOSS MUTATED | 32 | 82 | 40 |
| 17P LOSS WILD-TYPE | 53 | 21 | 66 |
Figure S321. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00612 (Fisher's exact test), Q value = 0.023
Table S322. Gene #70: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 17P LOSS MUTATED | 33 | 12 | 24 | 21 | 20 | 34 | 8 | 10 | 18 |
| 17P LOSS WILD-TYPE | 18 | 21 | 11 | 18 | 23 | 52 | 14 | 10 | 8 |
Figure S322. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S323. Gene #70: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 17P LOSS MUTATED | 94 | 24 | 48 | 69 |
| 17P LOSS WILD-TYPE | 33 | 70 | 49 | 62 |
Figure S323. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S324. Gene #70: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 17P LOSS MUTATED | 53 | 73 | 19 | 86 | 4 |
| 17P LOSS WILD-TYPE | 26 | 35 | 77 | 43 | 33 |
Figure S324. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S325. Gene #70: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 17P LOSS MUTATED | 46 | 26 | 38 | 58 | 42 |
| 17P LOSS WILD-TYPE | 14 | 62 | 33 | 17 | 62 |
Figure S325. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S326. Gene #70: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 17P LOSS MUTATED | 45 | 27 | 31 | 0 | 34 | 10 | 10 | 11 | 42 |
| 17P LOSS WILD-TYPE | 34 | 28 | 15 | 17 | 21 | 10 | 16 | 31 | 16 |
Figure S326. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0035 (Fisher's exact test), Q value = 0.015
Table S327. Gene #70: '17p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 17P LOSS MUTATED | 16 | 14 | 8 | 7 | 2 | 7 |
| 17P LOSS WILD-TYPE | 2 | 6 | 8 | 4 | 9 | 2 |
Figure S327. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0347 (Fisher's exact test), Q value = 0.097
Table S328. Gene #71: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 17Q LOSS MUTATED | 1 | 4 | 11 | 1 | 3 |
| 17Q LOSS WILD-TYPE | 30 | 13 | 38 | 26 | 20 |
Figure S328. Get High-res Image Gene #71: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S329. Gene #71: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 17Q LOSS MUTATED | 13 | 45 | 6 |
| 17Q LOSS WILD-TYPE | 40 | 176 | 171 |
Figure S329. Get High-res Image Gene #71: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0127 (Fisher's exact test), Q value = 0.043
Table S330. Gene #71: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 17Q LOSS MUTATED | 15 | 6 | 10 | 14 | 10 |
| 17Q LOSS WILD-TYPE | 45 | 82 | 61 | 61 | 94 |
Figure S330. Get High-res Image Gene #71: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S331. Gene #72: '18p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 18P LOSS MUTATED | 1 | 11 | 43 | 8 | 17 |
| 18P LOSS WILD-TYPE | 30 | 6 | 6 | 19 | 6 |
Figure S331. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S332. Gene #72: '18p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 18P LOSS MUTATED | 5 | 45 | 30 |
| 18P LOSS WILD-TYPE | 37 | 23 | 7 |
Figure S332. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S333. Gene #72: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 18P LOSS MUTATED | 37 | 191 | 24 |
| 18P LOSS WILD-TYPE | 16 | 30 | 153 |
Figure S333. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S334. Gene #72: '18p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 18P LOSS MUTATED | 37 | 96 | 36 |
| 18P LOSS WILD-TYPE | 48 | 7 | 70 |
Figure S334. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00384 (Fisher's exact test), Q value = 0.016
Table S335. Gene #72: '18p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 18P LOSS MUTATED | 31 | 18 | 23 | 20 | 25 | 35 | 8 | 11 | 22 |
| 18P LOSS WILD-TYPE | 20 | 15 | 12 | 19 | 18 | 51 | 14 | 9 | 4 |
Figure S335. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S336. Gene #72: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 18P LOSS MUTATED | 112 | 23 | 49 | 67 |
| 18P LOSS WILD-TYPE | 15 | 71 | 48 | 64 |
Figure S336. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S337. Gene #72: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 18P LOSS MUTATED | 61 | 83 | 14 | 91 | 2 |
| 18P LOSS WILD-TYPE | 18 | 25 | 82 | 38 | 35 |
Figure S337. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S338. Gene #72: '18p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 18P LOSS MUTATED | 50 | 27 | 43 | 58 | 41 |
| 18P LOSS WILD-TYPE | 10 | 61 | 28 | 17 | 63 |
Figure S338. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S339. Gene #72: '18p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 18P LOSS MUTATED | 46 | 28 | 37 | 1 | 30 | 10 | 13 | 9 | 45 |
| 18P LOSS WILD-TYPE | 33 | 27 | 9 | 16 | 25 | 10 | 13 | 33 | 13 |
Figure S339. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00027 (Fisher's exact test), Q value = 0.0016
Table S340. Gene #72: '18p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 18P LOSS MUTATED | 16 | 13 | 6 | 7 | 1 | 7 |
| 18P LOSS WILD-TYPE | 2 | 7 | 10 | 4 | 10 | 2 |
Figure S340. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00109 (Fisher's exact test), Q value = 0.0055
Table S341. Gene #72: '18p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 18P LOSS MUTATED | 10 | 6 | 6 | 6 | 2 | 1 | 5 | 8 | 6 |
| 18P LOSS WILD-TYPE | 2 | 3 | 2 | 6 | 7 | 6 | 8 | 1 | 0 |
Figure S341. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S342. Gene #73: '18q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 18Q LOSS MUTATED | 1 | 14 | 43 | 9 | 16 |
| 18Q LOSS WILD-TYPE | 30 | 3 | 6 | 18 | 7 |
Figure S342. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S343. Gene #73: '18q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 18Q LOSS MUTATED | 6 | 48 | 29 |
| 18Q LOSS WILD-TYPE | 36 | 20 | 8 |
Figure S343. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S344. Gene #73: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 18Q LOSS MUTATED | 38 | 199 | 31 |
| 18Q LOSS WILD-TYPE | 15 | 22 | 146 |
Figure S344. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S345. Gene #73: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 18Q LOSS MUTATED | 41 | 96 | 44 |
| 18Q LOSS WILD-TYPE | 44 | 7 | 62 |
Figure S345. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0128 (Fisher's exact test), Q value = 0.043
Table S346. Gene #73: '18q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 18Q LOSS MUTATED | 34 | 17 | 24 | 22 | 26 | 38 | 9 | 13 | 21 |
| 18Q LOSS WILD-TYPE | 17 | 16 | 11 | 17 | 17 | 48 | 13 | 7 | 5 |
Figure S346. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S347. Gene #73: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 18Q LOSS MUTATED | 112 | 28 | 55 | 72 |
| 18Q LOSS WILD-TYPE | 15 | 66 | 42 | 59 |
Figure S347. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S348. Gene #73: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 18Q LOSS MUTATED | 65 | 86 | 20 | 94 | 2 |
| 18Q LOSS WILD-TYPE | 14 | 22 | 76 | 35 | 35 |
Figure S348. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S349. Gene #73: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 18Q LOSS MUTATED | 50 | 32 | 44 | 62 | 46 |
| 18Q LOSS WILD-TYPE | 10 | 56 | 27 | 13 | 58 |
Figure S349. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S350. Gene #73: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 18Q LOSS MUTATED | 53 | 31 | 37 | 2 | 32 | 10 | 13 | 10 | 46 |
| 18Q LOSS WILD-TYPE | 26 | 24 | 9 | 15 | 23 | 10 | 13 | 32 | 12 |
Figure S350. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00019 (Fisher's exact test), Q value = 0.0012
Table S351. Gene #73: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 18Q LOSS MUTATED | 16 | 14 | 8 | 8 | 1 | 8 |
| 18Q LOSS WILD-TYPE | 2 | 6 | 8 | 3 | 10 | 1 |
Figure S351. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.013 (Fisher's exact test), Q value = 0.044
Table S352. Gene #73: '18q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| 18Q LOSS MUTATED | 10 | 7 | 6 | 7 | 3 | 2 | 6 | 9 | 5 |
| 18Q LOSS WILD-TYPE | 2 | 2 | 2 | 5 | 6 | 5 | 7 | 0 | 1 |
Figure S352. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00349 (Fisher's exact test), Q value = 0.015
Table S353. Gene #74: '19p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 19P LOSS MUTATED | 1 | 7 | 3 | 3 | 3 |
| 19P LOSS WILD-TYPE | 30 | 10 | 46 | 24 | 20 |
Figure S353. Get High-res Image Gene #74: '19p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0072 (Fisher's exact test), Q value = 0.026
Table S354. Gene #74: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 19P LOSS MUTATED | 6 | 27 | 7 |
| 19P LOSS WILD-TYPE | 47 | 194 | 170 |
Figure S354. Get High-res Image Gene #74: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00649 (Fisher's exact test), Q value = 0.024
Table S355. Gene #74: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 19P LOSS MUTATED | 20 | 3 | 5 | 12 |
| 19P LOSS WILD-TYPE | 107 | 91 | 92 | 119 |
Figure S355. Get High-res Image Gene #74: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0222 (Fisher's exact test), Q value = 0.068
Table S356. Gene #74: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 19P LOSS MUTATED | 4 | 15 | 3 | 16 | 2 |
| 19P LOSS WILD-TYPE | 75 | 93 | 93 | 113 | 35 |
Figure S356. Get High-res Image Gene #74: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0171 (Fisher's exact test), Q value = 0.054
Table S357. Gene #74: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 19P LOSS MUTATED | 6 | 0 | 4 | 0 | 10 | 3 | 1 | 3 | 8 |
| 19P LOSS WILD-TYPE | 73 | 55 | 42 | 17 | 45 | 17 | 25 | 39 | 50 |
Figure S357. Get High-res Image Gene #74: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00471 (Fisher's exact test), Q value = 0.018
Table S358. Gene #75: '19q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 19Q LOSS MUTATED | 1 | 7 | 4 | 2 | 2 |
| 19Q LOSS WILD-TYPE | 30 | 10 | 45 | 25 | 21 |
Figure S358. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00109 (Fisher's exact test), Q value = 0.0055
Table S359. Gene #75: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 19Q LOSS MUTATED | 7 | 22 | 4 |
| 19Q LOSS WILD-TYPE | 46 | 199 | 173 |
Figure S359. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0135 (Fisher's exact test), Q value = 0.045
Table S360. Gene #75: '19q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 19Q LOSS MUTATED | 16 | 2 | 4 | 11 |
| 19Q LOSS WILD-TYPE | 111 | 92 | 93 | 120 |
Figure S360. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0081 (Fisher's exact test), Q value = 0.029
Table S361. Gene #75: '19q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 19Q LOSS MUTATED | 1 | 12 | 3 | 15 | 2 |
| 19Q LOSS WILD-TYPE | 78 | 96 | 93 | 114 | 35 |
Figure S361. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0417 (Fisher's exact test), Q value = 0.11
Table S362. Gene #75: '19q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 18 | 20 | 16 | 11 | 11 | 9 |
| 19Q LOSS MUTATED | 4 | 0 | 1 | 0 | 0 | 2 |
| 19Q LOSS WILD-TYPE | 14 | 20 | 15 | 11 | 11 | 7 |
Figure S362. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0103 (Fisher's exact test), Q value = 0.036
Table S363. Gene #76: '20p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 20P LOSS MUTATED | 1 | 4 | 8 |
| 20P LOSS WILD-TYPE | 41 | 64 | 29 |
Figure S363. Get High-res Image Gene #76: '20p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S364. Gene #76: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 20P LOSS MUTATED | 0 | 39 | 4 |
| 20P LOSS WILD-TYPE | 53 | 182 | 173 |
Figure S364. Get High-res Image Gene #76: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0123 (Fisher's exact test), Q value = 0.042
Table S365. Gene #76: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 103 | 106 |
| 20P LOSS MUTATED | 6 | 17 | 5 |
| 20P LOSS WILD-TYPE | 79 | 86 | 101 |
Figure S365. Get High-res Image Gene #76: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0206 (Fisher's exact test), Q value = 0.064
Table S366. Gene #76: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 20P LOSS MUTATED | 14 | 11 | 3 | 13 | 2 |
| 20P LOSS WILD-TYPE | 65 | 97 | 93 | 116 | 35 |
Figure S366. Get High-res Image Gene #76: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S367. Gene #78: '21q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 21Q LOSS MUTATED | 2 | 8 | 23 | 3 | 3 |
| 21Q LOSS WILD-TYPE | 29 | 9 | 26 | 24 | 20 |
Figure S367. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0219 (Fisher's exact test), Q value = 0.067
Table S368. Gene #78: '21q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 21Q LOSS MUTATED | 5 | 24 | 10 |
| 21Q LOSS WILD-TYPE | 37 | 44 | 27 |
Figure S368. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S369. Gene #78: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 21Q LOSS MUTATED | 27 | 79 | 18 |
| 21Q LOSS WILD-TYPE | 26 | 142 | 159 |
Figure S369. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S370. Gene #78: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 21Q LOSS MUTATED | 58 | 12 | 23 | 30 |
| 21Q LOSS WILD-TYPE | 69 | 82 | 74 | 101 |
Figure S370. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0084 (Fisher's exact test), Q value = 0.03
Table S371. Gene #78: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 21Q LOSS MUTATED | 29 | 33 | 18 | 39 | 4 |
| 21Q LOSS WILD-TYPE | 50 | 75 | 78 | 90 | 33 |
Figure S371. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0477 (Fisher's exact test), Q value = 0.12
Table S372. Gene #78: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 21Q LOSS MUTATED | 22 | 18 | 22 | 24 | 20 |
| 21Q LOSS WILD-TYPE | 38 | 70 | 49 | 51 | 84 |
Figure S372. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00074
Table S373. Gene #79: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 31 | 17 | 49 | 27 | 23 |
| 22Q LOSS MUTATED | 3 | 10 | 25 | 5 | 9 |
| 22Q LOSS WILD-TYPE | 28 | 7 | 24 | 22 | 14 |
Figure S373. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S374. Gene #79: '22q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| 22Q LOSS MUTATED | 4 | 34 | 14 |
| 22Q LOSS WILD-TYPE | 38 | 34 | 23 |
Figure S374. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S375. Gene #79: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| 22Q LOSS MUTATED | 25 | 107 | 14 |
| 22Q LOSS WILD-TYPE | 28 | 114 | 163 |
Figure S375. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0064 (Fisher's exact test), Q value = 0.024
Table S376. Gene #79: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| 22Q LOSS MUTATED | 17 | 6 | 22 | 8 | 13 | 22 | 7 | 6 | 7 |
| 22Q LOSS WILD-TYPE | 34 | 27 | 13 | 31 | 30 | 64 | 15 | 14 | 19 |
Figure S376. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 5e-04
Table S377. Gene #79: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 94 | 97 | 131 |
| 22Q LOSS MUTATED | 53 | 13 | 32 | 47 |
| 22Q LOSS WILD-TYPE | 74 | 81 | 65 | 84 |
Figure S377. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.2e-05
Table S378. Gene #79: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 79 | 108 | 96 | 129 | 37 |
| 22Q LOSS MUTATED | 35 | 41 | 10 | 57 | 2 |
| 22Q LOSS WILD-TYPE | 44 | 67 | 86 | 72 | 35 |
Figure S378. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00023 (Fisher's exact test), Q value = 0.0014
Table S379. Gene #79: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| 22Q LOSS MUTATED | 23 | 14 | 27 | 34 | 26 |
| 22Q LOSS WILD-TYPE | 37 | 74 | 44 | 41 | 78 |
Figure S379. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00416 (Fisher's exact test), Q value = 0.017
Table S380. Gene #79: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| 22Q LOSS MUTATED | 27 | 17 | 20 | 0 | 17 | 2 | 8 | 9 | 24 |
| 22Q LOSS WILD-TYPE | 52 | 38 | 26 | 17 | 38 | 18 | 18 | 33 | 34 |
Figure S380. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0441 (Fisher's exact test), Q value = 0.11
Table S381. Gene #80: 'xp loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 42 | 68 | 37 |
| XP LOSS MUTATED | 2 | 15 | 5 |
| XP LOSS WILD-TYPE | 40 | 53 | 32 |
Figure S381. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00045 (Fisher's exact test), Q value = 0.0025
Table S382. Gene #80: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| XP LOSS MUTATED | 7 | 45 | 12 |
| XP LOSS WILD-TYPE | 46 | 176 | 165 |
Figure S382. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0206 (Fisher's exact test), Q value = 0.064
Table S383. Gene #80: 'xp loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 85 | 145 | 125 |
| XP LOSS MUTATED | 9 | 29 | 11 |
| XP LOSS WILD-TYPE | 76 | 116 | 114 |
Figure S383. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.005 (Fisher's exact test), Q value = 0.02
Table S384. Gene #80: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| XP LOSS MUTATED | 9 | 3 | 5 | 0 | 13 | 7 | 1 | 3 | 9 |
| XP LOSS WILD-TYPE | 70 | 52 | 41 | 17 | 42 | 13 | 25 | 39 | 49 |
Figure S384. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0122 (Fisher's exact test), Q value = 0.041
Table S385. Gene #80: 'xp loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| XP LOSS MUTATED | 0 | 0 | 1 | 2 | 0 | 2 | 2 | 1 | 4 |
| XP LOSS WILD-TYPE | 12 | 9 | 7 | 10 | 9 | 5 | 11 | 8 | 2 |
Figure S385. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0015
Table S386. Gene #81: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 53 | 221 | 177 |
| XQ LOSS MUTATED | 4 | 38 | 9 |
| XQ LOSS WILD-TYPE | 49 | 183 | 168 |
Figure S386. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0196 (Fisher's exact test), Q value = 0.061
Table S387. Gene #81: 'xq loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 51 | 33 | 35 | 39 | 43 | 86 | 22 | 20 | 26 |
| XQ LOSS MUTATED | 8 | 1 | 10 | 5 | 3 | 5 | 2 | 3 | 1 |
| XQ LOSS WILD-TYPE | 43 | 32 | 25 | 34 | 40 | 81 | 20 | 17 | 25 |
Figure S387. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00342 (Fisher's exact test), Q value = 0.015
Table S388. Gene #81: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 60 | 88 | 71 | 75 | 104 |
| XQ LOSS MUTATED | 13 | 4 | 3 | 11 | 9 |
| XQ LOSS WILD-TYPE | 47 | 84 | 68 | 64 | 95 |
Figure S388. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00708 (Fisher's exact test), Q value = 0.026
Table S389. Gene #81: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 79 | 55 | 46 | 17 | 55 | 20 | 26 | 42 | 58 |
| XQ LOSS MUTATED | 6 | 3 | 4 | 0 | 9 | 7 | 0 | 3 | 8 |
| XQ LOSS WILD-TYPE | 73 | 52 | 42 | 17 | 46 | 13 | 26 | 39 | 50 |
Figure S389. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00145 (Fisher's exact test), Q value = 0.007
Table S390. Gene #81: 'xq loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 | CLUS_8 | CLUS_9 |
|---|---|---|---|---|---|---|---|---|---|
| ALL | 12 | 9 | 8 | 12 | 9 | 7 | 13 | 9 | 6 |
| XQ LOSS MUTATED | 0 | 0 | 2 | 2 | 0 | 1 | 0 | 1 | 4 |
| XQ LOSS WILD-TYPE | 12 | 9 | 6 | 10 | 9 | 6 | 13 | 8 | 2 |
Figure S390. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
-
Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
-
Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/COAD-TP/22508740/transformed.cor.cli.txt
-
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/COAD-TP/22541003/COAD-TP.transferedmergedcluster.txt
-
Number of patients = 451
-
Number of significantly arm-level cnvs = 81
-
Number of molecular subtypes = 12
-
Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.