Correlation between copy number variation genes (focal events) and selected clinical features

Overview

Introduction

This pipeline computes the correlation between significant copy number variation (cnv focal) genes and selected clinical features.

Summary

Testing the association between copy number variation 101 focal events and 4 clinical features across 539 patients, 255 significant findings detected with Q value < 0.25.

amp_1p35.2 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_1p34.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_1q21.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_1q22 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_1q42.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_2p24.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_2q13 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
amp_3p25.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_3p14.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_3q26.2 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
amp_3q26.2 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_4p16.3 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_5p15.33 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_5q35.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_6p24.2 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_6q25.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_7q31.2 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_8p11.22 cnv correlated to 'Time to Death'.
amp_8p11.21 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_8q24.21 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_8q24.21 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_9p24.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_9q34.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_10q22.2 cnv correlated to 'HISTOLOGICAL_TYPE'.
amp_11p11.2 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_11q13.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_11q14.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_12p12.1 cnv correlated to 'RADIATION_THERAPY' and 'HISTOLOGICAL_TYPE'.
amp_12q13.11 cnv correlated to 'HISTOLOGICAL_TYPE'.
amp_12q13.2 cnv correlated to 'HISTOLOGICAL_TYPE' and 'RESIDUAL_TUMOR'.
amp_13q34 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_14q24.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_14q32.33 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_15q26.3 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_16p11.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_17q11.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_17q12 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_17q25.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_18p11.31 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_18q11.2 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_19p13.2 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_19p13.12 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_19q12 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_20p13 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
amp_20q11.21 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_20q13.12 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_20q13.33 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_22q12.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
amp_xp11.23 cnv correlated to 'HISTOLOGICAL_TYPE'.
amp_xq28 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_1p36.21 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_1p36.11 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_2p25.3 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
del_2q22.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_2q37.3 cnv correlated to 'HISTOLOGICAL_TYPE' and 'RESIDUAL_TUMOR'.
del_3p14.2 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_3q13.31 cnv correlated to 'HISTOLOGICAL_TYPE'.
del_4p16.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_4p15.31 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_4q22.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_4q34.3 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_5q12.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_6q26 cnv correlated to 'Time to Death', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
del_7p22.3 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_7q11.22 cnv correlated to 'HISTOLOGICAL_TYPE'.
del_7q31.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_7q36.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_8p23.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_8p21.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_9p23 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_9q21.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_9q34.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_10q21.1 cnv correlated to 'HISTOLOGICAL_TYPE'.
del_10q23.31 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_11p15.5 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_11q14.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_11q25 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_12q23.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_12q24.33 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_13q11 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_13q14.2 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_14q13.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_15q15.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_15q23 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_16p13.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_16q21 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_16q22.3 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_16q23.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_17p13.3 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_17p11.2 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_17q11.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_17q21.31 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_18q21.2 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_18q23 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_19p13.3 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_19p12 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_19q13.43 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_20p12.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_22q12.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.
del_22q13.32 cnv correlated to 'Time to Death' and 'HISTOLOGICAL_TYPE'.
del_xp21.1 cnv correlated to 'Time to Death', 'HISTOLOGICAL_TYPE', and 'RESIDUAL_TUMOR'.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between significant copy number variation of 101 focal events and 4 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 255 significant findings detected.


		Clinical Features	Time to Death	RADIATION THERAPY	HISTOLOGICAL TYPE	RESIDUAL TUMOR
	nCNV (%)	nWild-Type	logrank test	Fisher's exact test	Fisher's exact test	Fisher's exact test
amp 3q26 2	164 (30%)	375	0.000326 (0.000963)	0.0413 (0.0814)	1e-05 (4.04e-05)	0.124 (0.206)
amp 13q34	58 (11%)	481	0.0799 (0.148)	0.00677 (0.0159)	1e-05 (4.04e-05)	0.0128 (0.0285)
amp 15q26 3	38 (7%)	501	0.0456 (0.0886)	0.118 (0.199)	0.0001 (0.000337)	0.00573 (0.0137)
amp 18q11 2	69 (13%)	470	0.0264 (0.0552)	0.146 (0.234)	1e-05 (4.04e-05)	0.0557 (0.106)
amp 19q12	121 (22%)	418	3.14e-05 (0.000119)	0.13 (0.213)	1e-05 (4.04e-05)	0.0832 (0.153)
amp 1p34 2	73 (14%)	466	0.000233 (0.000719)	0.896 (0.948)	1e-05 (4.04e-05)	0.0969 (0.17)
amp 2q13	119 (22%)	420	2.71e-07 (4.04e-05)	0.132 (0.215)	1e-05 (4.04e-05)	0.198 (0.3)
amp 3q26 2	175 (32%)	364	7.41e-05 (0.000256)	0.0554 (0.106)	1e-05 (4.04e-05)	0.18 (0.28)
amp 4p16 3	52 (10%)	487	0.132 (0.215)	0.231 (0.342)	1e-05 (4.04e-05)	0.118 (0.199)
amp 5p15 33	89 (17%)	450	1.66e-06 (4.04e-05)	0.328 (0.449)	1e-05 (4.04e-05)	0.142 (0.23)
amp 6q25 1	88 (16%)	451	0.0348 (0.0692)	0.81 (0.889)	1e-05 (4.04e-05)	0.0422 (0.0827)
amp 8p11 21	162 (30%)	377	8.94e-05 (0.000306)	0.328 (0.449)	1e-05 (4.04e-05)	0.00419 (0.0103)
amp 8q24 21	209 (39%)	330	0.000101 (0.000338)	0.784 (0.877)	1e-05 (4.04e-05)	0.153 (0.244)
amp 8q24 21	215 (40%)	324	3.82e-05 (0.00014)	0.856 (0.927)	1e-05 (4.04e-05)	0.023 (0.0486)
amp 9p24 2	65 (12%)	474	0.0285 (0.0587)	0.48 (0.613)	1e-05 (4.04e-05)	0.0936 (0.166)
amp 11q13 2	74 (14%)	465	0.00854 (0.0198)	0.796 (0.883)	1e-05 (4.04e-05)	0.086 (0.156)
amp 11q14 1	60 (11%)	479	1.2e-05 (4.79e-05)	1 (1.00)	1e-05 (4.04e-05)	0.0283 (0.0587)
amp 16p11 2	66 (12%)	473	0.0329 (0.0661)	0.686 (0.799)	1e-05 (4.04e-05)	0.0604 (0.114)
amp 17q11 2	71 (13%)	468	3.34e-05 (0.000125)	0.895 (0.948)	1e-05 (4.04e-05)	0.00075 (0.00212)
amp 17q25 1	105 (19%)	434	1.45e-05 (5.7e-05)	0.427 (0.56)	1e-05 (4.04e-05)	0.0894 (0.16)
amp 18p11 31	96 (18%)	443	0.0447 (0.0872)	1 (1.00)	1e-05 (4.04e-05)	0.0713 (0.133)
amp 20q11 21	152 (28%)	387	5.65e-07 (4.04e-05)	0.485 (0.618)	1e-05 (4.04e-05)	0.046 (0.089)
amp 20q13 12	152 (28%)	387	0.000346 (0.00101)	0.92 (0.96)	1e-05 (4.04e-05)	0.0163 (0.036)
amp 20q13 33	153 (28%)	386	0.00453 (0.0111)	0.319 (0.443)	1e-05 (4.04e-05)	0.00257 (0.00657)
amp 22q12 2	62 (12%)	477	0.000308 (0.000928)	1 (1.00)	1e-05 (4.04e-05)	0.00172 (0.00454)
amp xq28	93 (17%)	446	0.00767 (0.0179)	0.407 (0.541)	0.00032 (0.000951)	0.158 (0.25)
del 1p36 11	83 (15%)	456	0.000102 (0.000338)	0.803 (0.884)	1e-05 (4.04e-05)	0.0498 (0.0959)
del 2p25 3	26 (5%)	513	0.00503 (0.0122)	0.0899 (0.16)	0.00993 (0.0225)	0.298 (0.416)
del 2q22 1	49 (9%)	490	8.17e-09 (3.3e-06)	0.538 (0.662)	1e-05 (4.04e-05)	0.00014 (0.000449)
del 4q22 1	106 (20%)	433	0.000117 (0.00038)	0.735 (0.837)	1e-05 (4.04e-05)	0.0328 (0.0661)
del 4q34 3	130 (24%)	409	0.000499 (0.00144)	0.754 (0.851)	1e-05 (4.04e-05)	0.0891 (0.16)
del 6q26	46 (9%)	493	0.123 (0.206)	0.0347 (0.0692)	1e-05 (4.04e-05)	0.871 (0.938)
del 7p22 3	72 (13%)	467	0.000786 (0.00221)	0.43 (0.562)	1e-05 (4.04e-05)	0.119 (0.2)
del 7q31 1	55 (10%)	484	0.0218 (0.0465)	0.188 (0.287)	1e-05 (4.04e-05)	0.145 (0.233)
del 8p23 2	119 (22%)	420	1.25e-05 (4.97e-05)	0.388 (0.522)	1e-05 (4.04e-05)	0.0316 (0.0641)
del 8p21 2	117 (22%)	422	0.000314 (0.000939)	0.449 (0.581)	1e-05 (4.04e-05)	0.0867 (0.157)
del 9q21 2	129 (24%)	410	5.69e-06 (4.04e-05)	1 (1.00)	1e-05 (4.04e-05)	0.102 (0.177)
del 9q34 2	132 (24%)	407	3.37e-05 (0.000125)	0.535 (0.661)	1e-05 (4.04e-05)	0.0712 (0.133)
del 10q23 31	78 (14%)	461	0.000184 (0.00058)	1 (1.00)	1e-05 (4.04e-05)	0.121 (0.203)
del 11p15 5	104 (19%)	435	0.000665 (0.00189)	0.817 (0.892)	1e-05 (4.04e-05)	0.0269 (0.056)
del 12q23 1	56 (10%)	483	6.25e-05 (0.00022)	0.306 (0.426)	1e-05 (4.04e-05)	0.0125 (0.0279)
del 12q24 33	66 (12%)	473	0.00307 (0.00771)	0.489 (0.619)	1e-05 (4.04e-05)	0.00903 (0.0208)
del 15q15 1	140 (26%)	399	7e-05 (0.000244)	0.539 (0.662)	1e-05 (4.04e-05)	0.0559 (0.106)
del 16q23 1	166 (31%)	373	0.00123 (0.00334)	0.771 (0.865)	1e-05 (4.04e-05)	0.0304 (0.062)
del 17p13 3	122 (23%)	417	1.07e-06 (4.04e-05)	0.517 (0.641)	1e-05 (4.04e-05)	0.0807 (0.149)
del 17q11 2	105 (19%)	434	0.000896 (0.00248)	0.495 (0.625)	1e-05 (4.04e-05)	0.115 (0.198)
del 17q21 31	114 (21%)	425	0.00013 (0.000421)	0.509 (0.637)	1e-05 (4.04e-05)	0.0206 (0.0443)
del 18q21 2	90 (17%)	449	0.0899 (0.16)	0.626 (0.748)	1e-05 (4.04e-05)	0.0378 (0.0749)
del 18q23	98 (18%)	441	0.00106 (0.00292)	0.238 (0.35)	1e-05 (4.04e-05)	0.00535 (0.0129)
del 19p13 3	157 (29%)	382	5.21e-07 (4.04e-05)	0.553 (0.675)	1e-05 (4.04e-05)	0.00313 (0.00781)
del 19p12	58 (11%)	481	0.0946 (0.167)	0.188 (0.287)	1e-05 (4.04e-05)	0.112 (0.193)
del 19q13 43	67 (12%)	472	0.00293 (0.00741)	0.677 (0.791)	1e-05 (4.04e-05)	0.0175 (0.0385)
del 20p12 1	35 (6%)	504	0.000108 (0.000353)	0.716 (0.824)	0.0001 (0.000337)	0.153 (0.244)
del 22q12 1	95 (18%)	444	0.00109 (0.00297)	0.635 (0.752)	1e-05 (4.04e-05)	0.129 (0.212)
del xp21 1	88 (16%)	451	7.7e-06 (4.04e-05)	0.628 (0.748)	1e-05 (4.04e-05)	0.111 (0.193)
amp 1p35 2	56 (10%)	483	0.112 (0.193)	0.882 (0.943)	1e-05 (4.04e-05)	0.222 (0.331)
amp 1q21 3	243 (45%)	296	0.0124 (0.0277)	0.655 (0.769)	1e-05 (4.04e-05)	0.566 (0.688)
amp 1q22	256 (47%)	283	0.00142 (0.00381)	0.929 (0.965)	1e-05 (4.04e-05)	0.378 (0.513)
amp 1q42 3	227 (42%)	312	0.0851 (0.156)	0.322 (0.444)	0.125 (0.207)	0.487 (0.618)
amp 2p24 3	122 (23%)	417	4.43e-06 (4.04e-05)	0.748 (0.846)	1e-05 (4.04e-05)	0.703 (0.812)
amp 3p25 1	82 (15%)	457	0.0988 (0.173)	1 (1.00)	1e-05 (4.04e-05)	0.541 (0.662)
amp 3p14 1	65 (12%)	474	0.00381 (0.00945)	0.889 (0.945)	2e-05 (7.77e-05)	0.229 (0.34)
amp 5q35 3	57 (11%)	482	5.46e-05 (0.000193)	0.768 (0.865)	1e-05 (4.04e-05)	0.411 (0.545)
amp 6p24 2	117 (22%)	422	0.0197 (0.0427)	0.829 (0.903)	1e-05 (4.04e-05)	0.57 (0.691)
amp 7q31 2	93 (17%)	446	2.95e-05 (0.000112)	0.812 (0.889)	4e-05 (0.000146)	0.696 (0.806)
amp 9q34 3	39 (7%)	500	0.00993 (0.0225)	0.86 (0.929)	1e-05 (4.04e-05)	0.405 (0.54)
amp 11p11 2	52 (10%)	487	0.000305 (0.000926)	0.881 (0.943)	1e-05 (4.04e-05)	0.513 (0.639)
amp 12p12 1	92 (17%)	447	0.282 (0.398)	0.126 (0.207)	1e-05 (4.04e-05)	0.74 (0.84)
amp 12q13 2	100 (19%)	439	0.469 (0.605)	0.73 (0.833)	1e-05 (4.04e-05)	0.117 (0.199)
amp 14q24 3	64 (12%)	475	0.00213 (0.00553)	0.339 (0.463)	1e-05 (4.04e-05)	0.509 (0.637)
amp 14q32 33	79 (15%)	460	0.000664 (0.00189)	0.801 (0.884)	1e-05 (4.04e-05)	0.206 (0.309)
amp 17q12	75 (14%)	464	5.12e-05 (0.000183)	0.247 (0.358)	1e-05 (4.04e-05)	0.238 (0.35)
amp 19p13 2	92 (17%)	447	0.0523 (0.1)	0.281 (0.397)	1e-05 (4.04e-05)	0.433 (0.565)
amp 19p13 12	99 (18%)	440	0.0196 (0.0427)	0.244 (0.356)	1e-05 (4.04e-05)	0.27 (0.388)
amp 20p13	117 (22%)	422	0.0202 (0.0437)	0.666 (0.78)	1e-05 (4.04e-05)	0.415 (0.548)
del 1p36 21	71 (13%)	468	0.00987 (0.0225)	0.793 (0.883)	1e-05 (4.04e-05)	0.637 (0.752)
del 2q37 3	52 (10%)	487	0.165 (0.26)	0.88 (0.943)	0.00026 (0.000796)	0.0291 (0.0596)
del 3p14 2	79 (15%)	460	0.00185 (0.00485)	0.376 (0.511)	1e-05 (4.04e-05)	0.636 (0.752)
del 4p16 3	94 (17%)	445	0.0235 (0.0495)	1 (1.00)	1e-05 (4.04e-05)	0.798 (0.883)
del 4p15 31	99 (18%)	440	0.00572 (0.0137)	0.909 (0.953)	1e-05 (4.04e-05)	0.288 (0.405)
del 5q12 1	111 (21%)	428	0.000214 (0.000664)	0.184 (0.284)	1e-05 (4.04e-05)	0.475 (0.61)
del 7q36 1	63 (12%)	476	0.00254 (0.00654)	0.279 (0.397)	1e-05 (4.04e-05)	0.28 (0.397)
del 9p23	80 (15%)	459	0.000841 (0.00234)	0.618 (0.741)	1e-05 (4.04e-05)	0.167 (0.262)
del 11q14 1	69 (13%)	470	0.00663 (0.0157)	0.426 (0.56)	1e-05 (4.04e-05)	0.591 (0.714)
del 11q25	94 (17%)	445	0.000197 (0.000618)	1 (1.00)	1e-05 (4.04e-05)	0.216 (0.324)
del 13q11	98 (18%)	441	0.00144 (0.00385)	0.908 (0.953)	1e-05 (4.04e-05)	0.272 (0.388)
del 13q14 2	106 (20%)	433	0.00016 (0.000507)	0.256 (0.369)	1e-05 (4.04e-05)	0.514 (0.639)
del 14q13 1	73 (14%)	466	0.00158 (0.00419)	1 (1.00)	1e-05 (4.04e-05)	0.985 (1.00)
del 15q23	115 (21%)	424	0.00675 (0.0159)	0.381 (0.515)	1e-05 (4.04e-05)	0.72 (0.826)
del 16p13 3	92 (17%)	447	4.95e-05 (0.000179)	0.905 (0.953)	1e-05 (4.04e-05)	0.162 (0.255)
del 16q21	154 (29%)	385	0.00204 (0.00532)	1 (1.00)	1e-05 (4.04e-05)	0.321 (0.444)
del 16q22 3	158 (29%)	381	0.0207 (0.0443)	0.922 (0.96)	1e-05 (4.04e-05)	0.248 (0.359)
del 17p11 2	128 (24%)	411	5.76e-06 (4.04e-05)	0.915 (0.958)	1e-05 (4.04e-05)	0.242 (0.354)
del 22q13 32	140 (26%)	399	2.75e-05 (0.000106)	0.838 (0.91)	1e-05 (4.04e-05)	0.199 (0.3)
amp 8p11 22	126 (23%)	413	0.0116 (0.0263)	0.598 (0.722)	0.884 (0.943)	0.692 (0.804)
amp 10q22 2	143 (27%)	396	0.187 (0.287)	0.618 (0.741)	0.0027 (0.00686)	0.249 (0.359)
amp 12q13 11	87 (16%)	452	0.472 (0.607)	0.177 (0.276)	1e-05 (4.04e-05)	0.193 (0.294)
amp xp11 23	90 (17%)	449	0.199 (0.3)	1 (1.00)	0.00044 (0.00128)	0.402 (0.538)
del 3q13 31	43 (8%)	496	0.79 (0.881)	1 (1.00)	1e-05 (4.04e-05)	0.729 (0.833)
del 7q11 22	41 (8%)	498	0.966 (1.00)	1 (1.00)	1e-05 (4.04e-05)	0.5 (0.629)
del 10q21 1	50 (9%)	489	0.448 (0.581)	0.641 (0.755)	1e-05 (4.04e-05)	0.401 (0.538)

'amp_1p35.2' versus 'Time to Death'

P value = 0.112 (logrank test), Q value = 0.19

Table S1. Gene #1: 'amp_1p35.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 1(1P35.2) MUTATED	56	14	0.1 - 118.2 (28.0)
AMP PEAK 1(1P35.2) WILD-TYPE	481	76	0.1 - 225.5 (30.0)

Figure S1. Get High-res Image Gene #1: 'amp_1p35.2' versus Clinical Feature #1: 'Time to Death'

'amp_1p35.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S2. Gene #1: 'amp_1p35.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 1(1P35.2) MUTATED	15	5	36
AMP PEAK 1(1P35.2) WILD-TYPE	389	17	77

Figure S2. Get High-res Image Gene #1: 'amp_1p35.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_1p34.2' versus 'Time to Death'

P value = 0.000233 (logrank test), Q value = 0.00072

Table S3. Gene #2: 'amp_1p34.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 2(1P34.2) MUTATED	73	22	0.1 - 125.4 (23.9)
AMP PEAK 2(1P34.2) WILD-TYPE	464	68	0.1 - 225.5 (30.1)

Figure S3. Get High-res Image Gene #2: 'amp_1p34.2' versus Clinical Feature #1: 'Time to Death'

'amp_1p34.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S4. Gene #2: 'amp_1p34.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 2(1P34.2) MUTATED	21	7	45
AMP PEAK 2(1P34.2) WILD-TYPE	383	15	68

Figure S4. Get High-res Image Gene #2: 'amp_1p34.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_1p34.2' versus 'RESIDUAL_TUMOR'

P value = 0.0969 (Fisher's exact test), Q value = 0.17

Table S5. Gene #2: 'amp_1p34.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 2(1P34.2) MUTATED	45	4	5	7
AMP PEAK 2(1P34.2) WILD-TYPE	326	18	11	33

Figure S5. Get High-res Image Gene #2: 'amp_1p34.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_1q21.3' versus 'Time to Death'

P value = 0.0124 (logrank test), Q value = 0.028

Table S6. Gene #3: 'amp_1q21.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 3(1Q21.3) MUTATED	242	51	0.1 - 149.6 (27.5)
AMP PEAK 3(1Q21.3) WILD-TYPE	295	39	0.2 - 225.5 (30.7)

Figure S6. Get High-res Image Gene #3: 'amp_1q21.3' versus Clinical Feature #1: 'Time to Death'

'amp_1q21.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S7. Gene #3: 'amp_1q21.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 3(1Q21.3) MUTATED	159	10	74
AMP PEAK 3(1Q21.3) WILD-TYPE	245	12	39

Figure S7. Get High-res Image Gene #3: 'amp_1q21.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_1q22' versus 'Time to Death'

P value = 0.00142 (logrank test), Q value = 0.0038

Table S8. Gene #4: 'amp_1q22' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 4(1Q22) MUTATED	256	56	0.1 - 149.6 (28.0)
AMP PEAK 4(1Q22) WILD-TYPE	281	34	0.2 - 225.5 (31.1)

Figure S8. Get High-res Image Gene #4: 'amp_1q22' versus Clinical Feature #1: 'Time to Death'

'amp_1q22' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S9. Gene #4: 'amp_1q22' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 4(1Q22) MUTATED	165	11	80
AMP PEAK 4(1Q22) WILD-TYPE	239	11	33

Figure S9. Get High-res Image Gene #4: 'amp_1q22' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_1q42.3' versus 'Time to Death'

P value = 0.0851 (logrank test), Q value = 0.16

Table S10. Gene #5: 'amp_1q42.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 5(1Q42.3) MUTATED	226	45	0.1 - 149.6 (29.9)
AMP PEAK 5(1Q42.3) WILD-TYPE	311	45	0.2 - 225.5 (29.9)

Figure S10. Get High-res Image Gene #5: 'amp_1q42.3' versus Clinical Feature #1: 'Time to Death'

'amp_1q42.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.125 (Fisher's exact test), Q value = 0.21

Table S11. Gene #5: 'amp_1q42.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 5(1Q42.3) MUTATED	162	8	57
AMP PEAK 5(1Q42.3) WILD-TYPE	242	14	56

Figure S11. Get High-res Image Gene #5: 'amp_1q42.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_2p24.3' versus 'Time to Death'

P value = 4.43e-06 (logrank test), Q value = 4e-05

Table S12. Gene #6: 'amp_2p24.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 6(2P24.3) MUTATED	121	36	0.1 - 149.6 (28.1)
AMP PEAK 6(2P24.3) WILD-TYPE	416	54	0.1 - 225.5 (30.7)

Figure S12. Get High-res Image Gene #6: 'amp_2p24.3' versus Clinical Feature #1: 'Time to Death'

'amp_2p24.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S13. Gene #6: 'amp_2p24.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 6(2P24.3) MUTATED	56	8	58
AMP PEAK 6(2P24.3) WILD-TYPE	348	14	55

Figure S13. Get High-res Image Gene #6: 'amp_2p24.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_2q13' versus 'Time to Death'

P value = 2.71e-07 (logrank test), Q value = 4e-05

Table S14. Gene #7: 'amp_2q13' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 7(2Q13) MUTATED	118	38	0.3 - 149.6 (27.0)
AMP PEAK 7(2Q13) WILD-TYPE	419	52	0.1 - 225.5 (30.4)

Figure S14. Get High-res Image Gene #7: 'amp_2q13' versus Clinical Feature #1: 'Time to Death'

'amp_2q13' versus 'RADIATION_THERAPY'

P value = 0.132 (Fisher's exact test), Q value = 0.21

Table S15. Gene #7: 'amp_2q13' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
AMP PEAK 7(2Q13) MUTATED	56	56
AMP PEAK 7(2Q13) WILD-TYPE	234	168

Figure S15. Get High-res Image Gene #7: 'amp_2q13' versus Clinical Feature #2: 'RADIATION_THERAPY'

'amp_2q13' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S16. Gene #7: 'amp_2q13' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 7(2Q13) MUTATED	45	6	68
AMP PEAK 7(2Q13) WILD-TYPE	359	16	45

Figure S16. Get High-res Image Gene #7: 'amp_2q13' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_3p25.1' versus 'Time to Death'

P value = 0.0988 (logrank test), Q value = 0.17

Table S17. Gene #8: 'amp_3p25.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 8(3P25.1) MUTATED	82	20	0.1 - 225.5 (31.2)
AMP PEAK 8(3P25.1) WILD-TYPE	455	70	0.1 - 185.8 (29.6)

Figure S17. Get High-res Image Gene #8: 'amp_3p25.1' versus Clinical Feature #1: 'Time to Death'

'amp_3p25.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S18. Gene #8: 'amp_3p25.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 8(3P25.1) MUTATED	36	2	44
AMP PEAK 8(3P25.1) WILD-TYPE	368	20	69

Figure S18. Get High-res Image Gene #8: 'amp_3p25.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_3p14.1' versus 'Time to Death'

P value = 0.00381 (logrank test), Q value = 0.0094

Table S19. Gene #9: 'amp_3p14.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 9(3P14.1) MUTATED	65	20	0.1 - 225.5 (28.6)
AMP PEAK 9(3P14.1) WILD-TYPE	472	70	0.1 - 185.8 (29.9)

Figure S19. Get High-res Image Gene #9: 'amp_3p14.1' versus Clinical Feature #1: 'Time to Death'

'amp_3p14.1' versus 'HISTOLOGICAL_TYPE'

P value = 2e-05 (Fisher's exact test), Q value = 7.8e-05

Table S20. Gene #9: 'amp_3p14.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 9(3P14.1) MUTATED	34	3	28
AMP PEAK 9(3P14.1) WILD-TYPE	370	19	85

Figure S20. Get High-res Image Gene #9: 'amp_3p14.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_3q26.2' versus 'Time to Death'

P value = 7.41e-05 (logrank test), Q value = 0.00026

Table S21. Gene #10: 'amp_3q26.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 10(3Q26.2) MUTATED	175	45	0.1 - 225.5 (28.9)
AMP PEAK 10(3Q26.2) WILD-TYPE	362	45	0.2 - 185.8 (30.3)

Figure S21. Get High-res Image Gene #10: 'amp_3q26.2' versus Clinical Feature #1: 'Time to Death'

'amp_3q26.2' versus 'RADIATION_THERAPY'

P value = 0.0554 (Fisher's exact test), Q value = 0.11

Table S22. Gene #10: 'amp_3q26.2' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
AMP PEAK 10(3Q26.2) MUTATED	81	81
AMP PEAK 10(3Q26.2) WILD-TYPE	209	143

Figure S22. Get High-res Image Gene #10: 'amp_3q26.2' versus Clinical Feature #2: 'RADIATION_THERAPY'

'amp_3q26.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S23. Gene #10: 'amp_3q26.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 10(3Q26.2) MUTATED	76	8	91
AMP PEAK 10(3Q26.2) WILD-TYPE	328	14	22

Figure S23. Get High-res Image Gene #10: 'amp_3q26.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_3q26.2' versus 'Time to Death'

P value = 0.000326 (logrank test), Q value = 0.00096

Table S24. Gene #11: 'amp_3q26.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 11(3Q26.2) MUTATED	164	42	0.1 - 225.5 (29.2)
AMP PEAK 11(3Q26.2) WILD-TYPE	373	48	0.2 - 185.8 (30.0)

Figure S24. Get High-res Image Gene #11: 'amp_3q26.2' versus Clinical Feature #1: 'Time to Death'

'amp_3q26.2' versus 'RADIATION_THERAPY'

P value = 0.0413 (Fisher's exact test), Q value = 0.081

Table S25. Gene #11: 'amp_3q26.2' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
AMP PEAK 11(3Q26.2) MUTATED	76	78
AMP PEAK 11(3Q26.2) WILD-TYPE	214	146

Figure S25. Get High-res Image Gene #11: 'amp_3q26.2' versus Clinical Feature #2: 'RADIATION_THERAPY'

'amp_3q26.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S26. Gene #11: 'amp_3q26.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 11(3Q26.2) MUTATED	68	8	88
AMP PEAK 11(3Q26.2) WILD-TYPE	336	14	25

Figure S26. Get High-res Image Gene #11: 'amp_3q26.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_3q26.2' versus 'RESIDUAL_TUMOR'

P value = 0.124 (Fisher's exact test), Q value = 0.21

Table S27. Gene #11: 'amp_3q26.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 11(3Q26.2) MUTATED	107	8	9	13
AMP PEAK 11(3Q26.2) WILD-TYPE	264	14	7	27

Figure S27. Get High-res Image Gene #11: 'amp_3q26.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_4p16.3' versus 'Time to Death'

P value = 0.132 (logrank test), Q value = 0.21

Table S28. Gene #12: 'amp_4p16.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 12(4P16.3) MUTATED	52	13	0.6 - 125.4 (29.2)
AMP PEAK 12(4P16.3) WILD-TYPE	485	77	0.1 - 225.5 (30.0)

Figure S28. Get High-res Image Gene #12: 'amp_4p16.3' versus Clinical Feature #1: 'Time to Death'

'amp_4p16.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S29. Gene #12: 'amp_4p16.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 12(4P16.3) MUTATED	14	2	36
AMP PEAK 12(4P16.3) WILD-TYPE	390	20	77

Figure S29. Get High-res Image Gene #12: 'amp_4p16.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_4p16.3' versus 'RESIDUAL_TUMOR'

P value = 0.118 (Fisher's exact test), Q value = 0.2

Table S30. Gene #12: 'amp_4p16.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 12(4P16.3) MUTATED	35	3	4	2
AMP PEAK 12(4P16.3) WILD-TYPE	336	19	12	38

Figure S30. Get High-res Image Gene #12: 'amp_4p16.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_5p15.33' versus 'Time to Death'

P value = 1.66e-06 (logrank test), Q value = 4e-05

Table S31. Gene #13: 'amp_5p15.33' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 13(5P15.33) MUTATED	88	28	0.2 - 125.4 (23.2)
AMP PEAK 13(5P15.33) WILD-TYPE	449	62	0.1 - 225.5 (30.1)

Figure S31. Get High-res Image Gene #13: 'amp_5p15.33' versus Clinical Feature #1: 'Time to Death'

'amp_5p15.33' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S32. Gene #13: 'amp_5p15.33' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 13(5P15.33) MUTATED	30	3	56
AMP PEAK 13(5P15.33) WILD-TYPE	374	19	57

Figure S32. Get High-res Image Gene #13: 'amp_5p15.33' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_5p15.33' versus 'RESIDUAL_TUMOR'

P value = 0.142 (Fisher's exact test), Q value = 0.23

Table S33. Gene #13: 'amp_5p15.33' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 13(5P15.33) MUTATED	58	3	6	8
AMP PEAK 13(5P15.33) WILD-TYPE	313	19	10	32

Figure S33. Get High-res Image Gene #13: 'amp_5p15.33' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_5q35.3' versus 'Time to Death'

P value = 5.46e-05 (logrank test), Q value = 0.00019

Table S34. Gene #14: 'amp_5q35.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 14(5Q35.3) MUTATED	56	18	0.4 - 110.6 (22.0)
AMP PEAK 14(5Q35.3) WILD-TYPE	481	72	0.1 - 225.5 (30.7)

Figure S34. Get High-res Image Gene #14: 'amp_5q35.3' versus Clinical Feature #1: 'Time to Death'

'amp_5q35.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S35. Gene #14: 'amp_5q35.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 14(5Q35.3) MUTATED	22	3	32
AMP PEAK 14(5Q35.3) WILD-TYPE	382	19	81

Figure S35. Get High-res Image Gene #14: 'amp_5q35.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_6p24.2' versus 'Time to Death'

P value = 0.0197 (logrank test), Q value = 0.043

Table S36. Gene #15: 'amp_6p24.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 15(6P24.2) MUTATED	117	30	0.1 - 125.4 (32.0)
AMP PEAK 15(6P24.2) WILD-TYPE	420	60	0.2 - 225.5 (28.5)

Figure S36. Get High-res Image Gene #15: 'amp_6p24.2' versus Clinical Feature #1: 'Time to Death'

'amp_6p24.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S37. Gene #15: 'amp_6p24.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 15(6P24.2) MUTATED	47	5	65
AMP PEAK 15(6P24.2) WILD-TYPE	357	17	48

Figure S37. Get High-res Image Gene #15: 'amp_6p24.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_6q25.1' versus 'Time to Death'

P value = 0.0348 (logrank test), Q value = 0.069

Table S38. Gene #16: 'amp_6q25.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 16(6Q25.1) MUTATED	88	21	0.1 - 109.1 (28.9)
AMP PEAK 16(6Q25.1) WILD-TYPE	449	69	0.2 - 225.5 (29.9)

Figure S38. Get High-res Image Gene #16: 'amp_6q25.1' versus Clinical Feature #1: 'Time to Death'

'amp_6q25.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S39. Gene #16: 'amp_6q25.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 16(6Q25.1) MUTATED	47	3	38
AMP PEAK 16(6Q25.1) WILD-TYPE	357	19	75

Figure S39. Get High-res Image Gene #16: 'amp_6q25.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_6q25.1' versus 'RESIDUAL_TUMOR'

P value = 0.0422 (Fisher's exact test), Q value = 0.083

Table S40. Gene #16: 'amp_6q25.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 16(6Q25.1) MUTATED	53	1	4	11
AMP PEAK 16(6Q25.1) WILD-TYPE	318	21	12	29

Figure S40. Get High-res Image Gene #16: 'amp_6q25.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_7q31.2' versus 'Time to Death'

P value = 2.95e-05 (logrank test), Q value = 0.00011

Table S41. Gene #17: 'amp_7q31.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 17(7Q31.2) MUTATED	92	27	0.2 - 125.4 (22.6)
AMP PEAK 17(7Q31.2) WILD-TYPE	445	63	0.1 - 225.5 (31.0)

Figure S41. Get High-res Image Gene #17: 'amp_7q31.2' versus Clinical Feature #1: 'Time to Death'

'amp_7q31.2' versus 'HISTOLOGICAL_TYPE'

P value = 4e-05 (Fisher's exact test), Q value = 0.00015

Table S42. Gene #17: 'amp_7q31.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 17(7Q31.2) MUTATED	53	5	35
AMP PEAK 17(7Q31.2) WILD-TYPE	351	17	78

Figure S42. Get High-res Image Gene #17: 'amp_7q31.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_8p11.22' versus 'Time to Death'

P value = 0.0116 (logrank test), Q value = 0.026

Table S43. Gene #18: 'amp_8p11.22' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 18(8P11.22) MUTATED	126	30	0.1 - 136.6 (30.1)
AMP PEAK 18(8P11.22) WILD-TYPE	411	60	0.1 - 225.5 (29.9)

Figure S43. Get High-res Image Gene #18: 'amp_8p11.22' versus Clinical Feature #1: 'Time to Death'

'amp_8p11.21' versus 'Time to Death'

P value = 8.94e-05 (logrank test), Q value = 0.00031

Table S44. Gene #19: 'amp_8p11.21' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 19(8P11.21) MUTATED	162	42	0.1 - 136.6 (27.5)
AMP PEAK 19(8P11.21) WILD-TYPE	375	48	0.2 - 225.5 (30.1)

Figure S44. Get High-res Image Gene #19: 'amp_8p11.21' versus Clinical Feature #1: 'Time to Death'

'amp_8p11.21' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S45. Gene #19: 'amp_8p11.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 19(8P11.21) MUTATED	95	7	60
AMP PEAK 19(8P11.21) WILD-TYPE	309	15	53

Figure S45. Get High-res Image Gene #19: 'amp_8p11.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_8p11.21' versus 'RESIDUAL_TUMOR'

P value = 0.00419 (Fisher's exact test), Q value = 0.01

Table S46. Gene #19: 'amp_8p11.21' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 19(8P11.21) MUTATED	106	4	11	15
AMP PEAK 19(8P11.21) WILD-TYPE	265	18	5	25

Figure S46. Get High-res Image Gene #19: 'amp_8p11.21' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_8q24.21' versus 'Time to Death'

P value = 0.000101 (logrank test), Q value = 0.00034

Table S47. Gene #20: 'amp_8q24.21' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 20(8Q24.21) MUTATED	207	51	0.1 - 225.5 (27.4)
AMP PEAK 20(8Q24.21) WILD-TYPE	330	39	0.2 - 185.8 (30.6)

Figure S47. Get High-res Image Gene #20: 'amp_8q24.21' versus Clinical Feature #1: 'Time to Death'

'amp_8q24.21' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S48. Gene #20: 'amp_8q24.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 20(8Q24.21) MUTATED	118	11	80
AMP PEAK 20(8Q24.21) WILD-TYPE	286	11	33

Figure S48. Get High-res Image Gene #20: 'amp_8q24.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_8q24.21' versus 'RESIDUAL_TUMOR'

P value = 0.153 (Fisher's exact test), Q value = 0.24

Table S49. Gene #20: 'amp_8q24.21' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 20(8Q24.21) MUTATED	140	6	10	17
AMP PEAK 20(8Q24.21) WILD-TYPE	231	16	6	23

Figure S49. Get High-res Image Gene #20: 'amp_8q24.21' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_8q24.21' versus 'Time to Death'

P value = 3.82e-05 (logrank test), Q value = 0.00014

Table S50. Gene #21: 'amp_8q24.21' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 21(8Q24.21) MUTATED	213	53	0.1 - 225.5 (27.2)
AMP PEAK 21(8Q24.21) WILD-TYPE	324	37	0.2 - 185.8 (30.7)

Figure S50. Get High-res Image Gene #21: 'amp_8q24.21' versus Clinical Feature #1: 'Time to Death'

'amp_8q24.21' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S51. Gene #21: 'amp_8q24.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 21(8Q24.21) MUTATED	121	10	84
AMP PEAK 21(8Q24.21) WILD-TYPE	283	12	29

Figure S51. Get High-res Image Gene #21: 'amp_8q24.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_8q24.21' versus 'RESIDUAL_TUMOR'

P value = 0.023 (Fisher's exact test), Q value = 0.049

Table S52. Gene #21: 'amp_8q24.21' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 21(8Q24.21) MUTATED	145	6	12	16
AMP PEAK 21(8Q24.21) WILD-TYPE	226	16	4	24

Figure S52. Get High-res Image Gene #21: 'amp_8q24.21' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_9p24.2' versus 'Time to Death'

P value = 0.0285 (logrank test), Q value = 0.059

Table S53. Gene #22: 'amp_9p24.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 22(9P24.2) MUTATED	64	18	0.1 - 125.4 (30.6)
AMP PEAK 22(9P24.2) WILD-TYPE	473	72	0.1 - 225.5 (29.9)

Figure S53. Get High-res Image Gene #22: 'amp_9p24.2' versus Clinical Feature #1: 'Time to Death'

'amp_9p24.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S54. Gene #22: 'amp_9p24.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 22(9P24.2) MUTATED	26	3	36
AMP PEAK 22(9P24.2) WILD-TYPE	378	19	77

Figure S54. Get High-res Image Gene #22: 'amp_9p24.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_9p24.2' versus 'RESIDUAL_TUMOR'

P value = 0.0936 (Fisher's exact test), Q value = 0.17

Table S55. Gene #22: 'amp_9p24.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 22(9P24.2) MUTATED	39	3	3	9
AMP PEAK 22(9P24.2) WILD-TYPE	332	19	13	31

Figure S55. Get High-res Image Gene #22: 'amp_9p24.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_9q34.3' versus 'Time to Death'

P value = 0.00993 (logrank test), Q value = 0.023

Table S56. Gene #23: 'amp_9q34.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 23(9Q34.3) MUTATED	39	11	0.1 - 71.2 (27.3)
AMP PEAK 23(9Q34.3) WILD-TYPE	498	79	0.1 - 225.5 (30.0)

Figure S56. Get High-res Image Gene #23: 'amp_9q34.3' versus Clinical Feature #1: 'Time to Death'

'amp_9q34.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S57. Gene #23: 'amp_9q34.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 23(9Q34.3) MUTATED	13	5	21
AMP PEAK 23(9Q34.3) WILD-TYPE	391	17	92

Figure S57. Get High-res Image Gene #23: 'amp_9q34.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_10q22.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.0027 (Fisher's exact test), Q value = 0.0069

Table S58. Gene #24: 'amp_10q22.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 24(10Q22.2) MUTATED	96	3	44
AMP PEAK 24(10Q22.2) WILD-TYPE	308	19	69

Figure S58. Get High-res Image Gene #24: 'amp_10q22.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_11p11.2' versus 'Time to Death'

P value = 0.000305 (logrank test), Q value = 0.00093

Table S59. Gene #25: 'amp_11p11.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 25(11P11.2) MUTATED	52	18	1.4 - 110.6 (27.1)
AMP PEAK 25(11P11.2) WILD-TYPE	485	72	0.1 - 225.5 (30.0)

Figure S59. Get High-res Image Gene #25: 'amp_11p11.2' versus Clinical Feature #1: 'Time to Death'

'amp_11p11.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S60. Gene #25: 'amp_11p11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 25(11P11.2) MUTATED	17	4	31
AMP PEAK 25(11P11.2) WILD-TYPE	387	18	82

Figure S60. Get High-res Image Gene #25: 'amp_11p11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_11q13.2' versus 'Time to Death'

P value = 0.00854 (logrank test), Q value = 0.02

Table S61. Gene #26: 'amp_11q13.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 26(11Q13.2) MUTATED	74	20	0.1 - 109.1 (30.6)
AMP PEAK 26(11Q13.2) WILD-TYPE	463	70	0.1 - 225.5 (29.7)

Figure S61. Get High-res Image Gene #26: 'amp_11q13.2' versus Clinical Feature #1: 'Time to Death'

'amp_11q13.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S62. Gene #26: 'amp_11q13.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 26(11Q13.2) MUTATED	36	4	34
AMP PEAK 26(11Q13.2) WILD-TYPE	368	18	79

Figure S62. Get High-res Image Gene #26: 'amp_11q13.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_11q13.2' versus 'RESIDUAL_TUMOR'

P value = 0.086 (Fisher's exact test), Q value = 0.16

Table S63. Gene #26: 'amp_11q13.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 26(11Q13.2) MUTATED	43	2	3	10
AMP PEAK 26(11Q13.2) WILD-TYPE	328	20	13	30

Figure S63. Get High-res Image Gene #26: 'amp_11q13.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_11q14.1' versus 'Time to Death'

P value = 1.2e-05 (logrank test), Q value = 4.8e-05

Table S64. Gene #27: 'amp_11q14.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 27(11Q14.1) MUTATED	60	21	0.4 - 109.1 (25.9)
AMP PEAK 27(11Q14.1) WILD-TYPE	477	69	0.1 - 225.5 (30.1)

Figure S64. Get High-res Image Gene #27: 'amp_11q14.1' versus Clinical Feature #1: 'Time to Death'

'amp_11q14.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S65. Gene #27: 'amp_11q14.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 27(11Q14.1) MUTATED	24	1	35
AMP PEAK 27(11Q14.1) WILD-TYPE	380	21	78

Figure S65. Get High-res Image Gene #27: 'amp_11q14.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_11q14.1' versus 'RESIDUAL_TUMOR'

P value = 0.0283 (Fisher's exact test), Q value = 0.059

Table S66. Gene #27: 'amp_11q14.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 27(11Q14.1) MUTATED	33	1	3	9
AMP PEAK 27(11Q14.1) WILD-TYPE	338	21	13	31

Figure S66. Get High-res Image Gene #27: 'amp_11q14.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_12p12.1' versus 'RADIATION_THERAPY'

P value = 0.126 (Fisher's exact test), Q value = 0.21

Table S67. Gene #28: 'amp_12p12.1' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
AMP PEAK 28(12P12.1) MUTATED	43	45
AMP PEAK 28(12P12.1) WILD-TYPE	247	179

Figure S67. Get High-res Image Gene #28: 'amp_12p12.1' versus Clinical Feature #2: 'RADIATION_THERAPY'

'amp_12p12.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S68. Gene #28: 'amp_12p12.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 28(12P12.1) MUTATED	44	4	44
AMP PEAK 28(12P12.1) WILD-TYPE	360	18	69

Figure S68. Get High-res Image Gene #28: 'amp_12p12.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_12q13.11' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S69. Gene #29: 'amp_12q13.11' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 29(12Q13.11) MUTATED	41	4	42
AMP PEAK 29(12Q13.11) WILD-TYPE	363	18	71

Figure S69. Get High-res Image Gene #29: 'amp_12q13.11' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_12q13.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S70. Gene #30: 'amp_12q13.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 30(12Q13.2) MUTATED	51	4	45
AMP PEAK 30(12Q13.2) WILD-TYPE	353	18	68

Figure S70. Get High-res Image Gene #30: 'amp_12q13.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_12q13.2' versus 'RESIDUAL_TUMOR'

P value = 0.117 (Fisher's exact test), Q value = 0.2

Table S71. Gene #30: 'amp_12q13.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 30(12Q13.2) MUTATED	70	3	7	7
AMP PEAK 30(12Q13.2) WILD-TYPE	301	19	9	33

Figure S71. Get High-res Image Gene #30: 'amp_12q13.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_13q34' versus 'Time to Death'

P value = 0.0799 (logrank test), Q value = 0.15

Table S72. Gene #31: 'amp_13q34' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 31(13Q34) MUTATED	58	14	0.6 - 125.4 (25.6)
AMP PEAK 31(13Q34) WILD-TYPE	479	76	0.1 - 225.5 (30.1)

Figure S72. Get High-res Image Gene #31: 'amp_13q34' versus Clinical Feature #1: 'Time to Death'

'amp_13q34' versus 'RADIATION_THERAPY'

P value = 0.00677 (Fisher's exact test), Q value = 0.016

Table S73. Gene #31: 'amp_13q34' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
AMP PEAK 31(13Q34) MUTATED	22	34
AMP PEAK 31(13Q34) WILD-TYPE	268	190

Figure S73. Get High-res Image Gene #31: 'amp_13q34' versus Clinical Feature #2: 'RADIATION_THERAPY'

'amp_13q34' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S74. Gene #31: 'amp_13q34' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 31(13Q34) MUTATED	14	4	40
AMP PEAK 31(13Q34) WILD-TYPE	390	18	73

Figure S74. Get High-res Image Gene #31: 'amp_13q34' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_13q34' versus 'RESIDUAL_TUMOR'

P value = 0.0128 (Fisher's exact test), Q value = 0.029

Table S75. Gene #31: 'amp_13q34' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 31(13Q34) MUTATED	35	6	4	6
AMP PEAK 31(13Q34) WILD-TYPE	336	16	12	34

Figure S75. Get High-res Image Gene #31: 'amp_13q34' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_14q24.3' versus 'Time to Death'

P value = 0.00213 (logrank test), Q value = 0.0055

Table S76. Gene #32: 'amp_14q24.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 32(14Q24.3) MUTATED	64	21	0.4 - 125.4 (28.8)
AMP PEAK 32(14Q24.3) WILD-TYPE	473	69	0.1 - 225.5 (29.9)

Figure S76. Get High-res Image Gene #32: 'amp_14q24.3' versus Clinical Feature #1: 'Time to Death'

'amp_14q24.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S77. Gene #32: 'amp_14q24.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 32(14Q24.3) MUTATED	22	4	38
AMP PEAK 32(14Q24.3) WILD-TYPE	382	18	75

Figure S77. Get High-res Image Gene #32: 'amp_14q24.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_14q32.33' versus 'Time to Death'

P value = 0.000664 (logrank test), Q value = 0.0019

Table S78. Gene #33: 'amp_14q32.33' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 33(14Q32.33) MUTATED	78	24	0.3 - 118.2 (28.0)
AMP PEAK 33(14Q32.33) WILD-TYPE	459	66	0.1 - 225.5 (30.0)

Figure S78. Get High-res Image Gene #33: 'amp_14q32.33' versus Clinical Feature #1: 'Time to Death'

'amp_14q32.33' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S79. Gene #33: 'amp_14q32.33' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 33(14Q32.33) MUTATED	33	5	41
AMP PEAK 33(14Q32.33) WILD-TYPE	371	17	72

Figure S79. Get High-res Image Gene #33: 'amp_14q32.33' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_15q26.3' versus 'Time to Death'

P value = 0.0456 (logrank test), Q value = 0.089

Table S80. Gene #34: 'amp_15q26.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 34(15Q26.3) MUTATED	38	12	1.7 - 110.1 (34.5)
AMP PEAK 34(15Q26.3) WILD-TYPE	499	78	0.1 - 225.5 (29.6)

Figure S80. Get High-res Image Gene #34: 'amp_15q26.3' versus Clinical Feature #1: 'Time to Death'

'amp_15q26.3' versus 'RADIATION_THERAPY'

P value = 0.118 (Fisher's exact test), Q value = 0.2

Table S81. Gene #34: 'amp_15q26.3' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
AMP PEAK 34(15Q26.3) MUTATED	25	11
AMP PEAK 34(15Q26.3) WILD-TYPE	265	213

Figure S81. Get High-res Image Gene #34: 'amp_15q26.3' versus Clinical Feature #2: 'RADIATION_THERAPY'

'amp_15q26.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-04 (Fisher's exact test), Q value = 0.00034

Table S82. Gene #34: 'amp_15q26.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 34(15Q26.3) MUTATED	18	1	19
AMP PEAK 34(15Q26.3) WILD-TYPE	386	21	94

Figure S82. Get High-res Image Gene #34: 'amp_15q26.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_15q26.3' versus 'RESIDUAL_TUMOR'

P value = 0.00573 (Fisher's exact test), Q value = 0.014

Table S83. Gene #34: 'amp_15q26.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 34(15Q26.3) MUTATED	20	3	4	5
AMP PEAK 34(15Q26.3) WILD-TYPE	351	19	12	35

Figure S83. Get High-res Image Gene #34: 'amp_15q26.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_16p11.2' versus 'Time to Death'

P value = 0.0329 (logrank test), Q value = 0.066

Table S84. Gene #35: 'amp_16p11.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 35(16P11.2) MUTATED	66	17	0.1 - 118.2 (28.6)
AMP PEAK 35(16P11.2) WILD-TYPE	471	73	0.1 - 225.5 (30.0)

Figure S84. Get High-res Image Gene #35: 'amp_16p11.2' versus Clinical Feature #1: 'Time to Death'

'amp_16p11.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S85. Gene #35: 'amp_16p11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 35(16P11.2) MUTATED	23	2	41
AMP PEAK 35(16P11.2) WILD-TYPE	381	20	72

Figure S85. Get High-res Image Gene #35: 'amp_16p11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_16p11.2' versus 'RESIDUAL_TUMOR'

P value = 0.0604 (Fisher's exact test), Q value = 0.11

Table S86. Gene #35: 'amp_16p11.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 35(16P11.2) MUTATED	41	3	3	10
AMP PEAK 35(16P11.2) WILD-TYPE	330	19	13	30

Figure S86. Get High-res Image Gene #35: 'amp_16p11.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_17q11.2' versus 'Time to Death'

P value = 3.34e-05 (logrank test), Q value = 0.00012

Table S87. Gene #36: 'amp_17q11.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 36(17Q11.2) MUTATED	71	23	0.1 - 118.2 (27.3)
AMP PEAK 36(17Q11.2) WILD-TYPE	466	67	0.1 - 225.5 (30.1)

Figure S87. Get High-res Image Gene #36: 'amp_17q11.2' versus Clinical Feature #1: 'Time to Death'

'amp_17q11.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S88. Gene #36: 'amp_17q11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 36(17Q11.2) MUTATED	19	6	46
AMP PEAK 36(17Q11.2) WILD-TYPE	385	16	67

Figure S88. Get High-res Image Gene #36: 'amp_17q11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_17q11.2' versus 'RESIDUAL_TUMOR'

P value = 0.00075 (Fisher's exact test), Q value = 0.0021

Table S89. Gene #36: 'amp_17q11.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 36(17Q11.2) MUTATED	39	7	6	7
AMP PEAK 36(17Q11.2) WILD-TYPE	332	15	10	33

Figure S89. Get High-res Image Gene #36: 'amp_17q11.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_17q12' versus 'Time to Death'

P value = 5.12e-05 (logrank test), Q value = 0.00018

Table S90. Gene #37: 'amp_17q12' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 37(17Q12) MUTATED	75	24	0.1 - 110.6 (27.4)
AMP PEAK 37(17Q12) WILD-TYPE	462	66	0.1 - 225.5 (30.1)

Figure S90. Get High-res Image Gene #37: 'amp_17q12' versus Clinical Feature #1: 'Time to Death'

'amp_17q12' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S91. Gene #37: 'amp_17q12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 37(17Q12) MUTATED	20	4	51
AMP PEAK 37(17Q12) WILD-TYPE	384	18	62

Figure S91. Get High-res Image Gene #37: 'amp_17q12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_17q25.1' versus 'Time to Death'

P value = 1.45e-05 (logrank test), Q value = 5.7e-05

Table S92. Gene #38: 'amp_17q25.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 38(17Q25.1) MUTATED	105	32	0.1 - 125.4 (25.9)
AMP PEAK 38(17Q25.1) WILD-TYPE	432	58	0.1 - 225.5 (30.7)

Figure S92. Get High-res Image Gene #38: 'amp_17q25.1' versus Clinical Feature #1: 'Time to Death'

'amp_17q25.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S93. Gene #38: 'amp_17q25.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 38(17Q25.1) MUTATED	39	9	57
AMP PEAK 38(17Q25.1) WILD-TYPE	365	13	56

Figure S93. Get High-res Image Gene #38: 'amp_17q25.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_17q25.1' versus 'RESIDUAL_TUMOR'

P value = 0.0894 (Fisher's exact test), Q value = 0.16

Table S94. Gene #38: 'amp_17q25.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 38(17Q25.1) MUTATED	66	4	5	13
AMP PEAK 38(17Q25.1) WILD-TYPE	305	18	11	27

Figure S94. Get High-res Image Gene #38: 'amp_17q25.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_18p11.31' versus 'Time to Death'

P value = 0.0447 (logrank test), Q value = 0.087

Table S95. Gene #39: 'amp_18p11.31' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 39(18P11.31) MUTATED	96	23	0.4 - 125.4 (31.3)
AMP PEAK 39(18P11.31) WILD-TYPE	441	67	0.1 - 225.5 (29.7)

Figure S95. Get High-res Image Gene #39: 'amp_18p11.31' versus Clinical Feature #1: 'Time to Death'

'amp_18p11.31' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S96. Gene #39: 'amp_18p11.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 39(18P11.31) MUTATED	30	6	60
AMP PEAK 39(18P11.31) WILD-TYPE	374	16	53

Figure S96. Get High-res Image Gene #39: 'amp_18p11.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_18p11.31' versus 'RESIDUAL_TUMOR'

P value = 0.0713 (Fisher's exact test), Q value = 0.13

Table S97. Gene #39: 'amp_18p11.31' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 39(18P11.31) MUTATED	63	3	7	8
AMP PEAK 39(18P11.31) WILD-TYPE	308	19	9	32

Figure S97. Get High-res Image Gene #39: 'amp_18p11.31' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_18q11.2' versus 'Time to Death'

P value = 0.0264 (logrank test), Q value = 0.055

Table S98. Gene #40: 'amp_18q11.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 40(18Q11.2) MUTATED	69	19	1.4 - 125.4 (31.4)
AMP PEAK 40(18Q11.2) WILD-TYPE	468	71	0.1 - 225.5 (29.8)

Figure S98. Get High-res Image Gene #40: 'amp_18q11.2' versus Clinical Feature #1: 'Time to Death'

'amp_18q11.2' versus 'RADIATION_THERAPY'

P value = 0.146 (Fisher's exact test), Q value = 0.23

Table S99. Gene #40: 'amp_18q11.2' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
AMP PEAK 40(18Q11.2) MUTATED	32	35
AMP PEAK 40(18Q11.2) WILD-TYPE	258	189

Figure S99. Get High-res Image Gene #40: 'amp_18q11.2' versus Clinical Feature #2: 'RADIATION_THERAPY'

'amp_18q11.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S100. Gene #40: 'amp_18q11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 40(18Q11.2) MUTATED	21	4	44
AMP PEAK 40(18Q11.2) WILD-TYPE	383	18	69

Figure S100. Get High-res Image Gene #40: 'amp_18q11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_18q11.2' versus 'RESIDUAL_TUMOR'

P value = 0.0557 (Fisher's exact test), Q value = 0.11

Table S101. Gene #40: 'amp_18q11.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 40(18Q11.2) MUTATED	43	1	4	9
AMP PEAK 40(18Q11.2) WILD-TYPE	328	21	12	31

Figure S101. Get High-res Image Gene #40: 'amp_18q11.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_19p13.2' versus 'Time to Death'

P value = 0.0523 (logrank test), Q value = 0.1

Table S102. Gene #41: 'amp_19p13.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 41(19P13.2) MUTATED	91	23	0.1 - 125.4 (31.1)
AMP PEAK 41(19P13.2) WILD-TYPE	446	67	0.1 - 225.5 (29.8)

Figure S102. Get High-res Image Gene #41: 'amp_19p13.2' versus Clinical Feature #1: 'Time to Death'

'amp_19p13.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S103. Gene #41: 'amp_19p13.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 41(19P13.2) MUTATED	29	8	55
AMP PEAK 41(19P13.2) WILD-TYPE	375	14	58

Figure S103. Get High-res Image Gene #41: 'amp_19p13.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_19p13.12' versus 'Time to Death'

P value = 0.0196 (logrank test), Q value = 0.043

Table S104. Gene #42: 'amp_19p13.12' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 42(19P13.12) MUTATED	98	24	0.1 - 125.4 (27.9)
AMP PEAK 42(19P13.12) WILD-TYPE	439	66	0.1 - 225.5 (30.1)

Figure S104. Get High-res Image Gene #42: 'amp_19p13.12' versus Clinical Feature #1: 'Time to Death'

'amp_19p13.12' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S105. Gene #42: 'amp_19p13.12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 42(19P13.12) MUTATED	30	7	62
AMP PEAK 42(19P13.12) WILD-TYPE	374	15	51

Figure S105. Get High-res Image Gene #42: 'amp_19p13.12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_19q12' versus 'Time to Death'

P value = 3.14e-05 (logrank test), Q value = 0.00012

Table S106. Gene #43: 'amp_19q12' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 43(19Q12) MUTATED	120	34	0.1 - 125.4 (26.0)
AMP PEAK 43(19Q12) WILD-TYPE	417	56	0.2 - 225.5 (30.7)

Figure S106. Get High-res Image Gene #43: 'amp_19q12' versus Clinical Feature #1: 'Time to Death'

'amp_19q12' versus 'RADIATION_THERAPY'

P value = 0.13 (Fisher's exact test), Q value = 0.21

Table S107. Gene #43: 'amp_19q12' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
AMP PEAK 43(19Q12) MUTATED	55	55
AMP PEAK 43(19Q12) WILD-TYPE	235	169

Figure S107. Get High-res Image Gene #43: 'amp_19q12' versus Clinical Feature #2: 'RADIATION_THERAPY'

'amp_19q12' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S108. Gene #43: 'amp_19q12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 43(19Q12) MUTATED	32	11	78
AMP PEAK 43(19Q12) WILD-TYPE	372	11	35

Figure S108. Get High-res Image Gene #43: 'amp_19q12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_19q12' versus 'RESIDUAL_TUMOR'

P value = 0.0832 (Fisher's exact test), Q value = 0.15

Table S109. Gene #43: 'amp_19q12' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 43(19Q12) MUTATED	76	5	6	14
AMP PEAK 43(19Q12) WILD-TYPE	295	17	10	26

Figure S109. Get High-res Image Gene #43: 'amp_19q12' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_20p13' versus 'Time to Death'

P value = 0.0202 (logrank test), Q value = 0.044

Table S110. Gene #44: 'amp_20p13' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 44(20P13) MUTATED	117	27	0.1 - 136.6 (28.7)
AMP PEAK 44(20P13) WILD-TYPE	420	63	0.1 - 225.5 (30.1)

Figure S110. Get High-res Image Gene #44: 'amp_20p13' versus Clinical Feature #1: 'Time to Death'

'amp_20p13' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S111. Gene #44: 'amp_20p13' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 44(20P13) MUTATED	53	5	59
AMP PEAK 44(20P13) WILD-TYPE	351	17	54

Figure S111. Get High-res Image Gene #44: 'amp_20p13' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_20q11.21' versus 'Time to Death'

P value = 5.65e-07 (logrank test), Q value = 4e-05

Table S112. Gene #45: 'amp_20q11.21' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 45(20Q11.21) MUTATED	151	44	0.1 - 149.6 (27.9)
AMP PEAK 45(20Q11.21) WILD-TYPE	386	46	0.1 - 225.5 (30.7)

Figure S112. Get High-res Image Gene #45: 'amp_20q11.21' versus Clinical Feature #1: 'Time to Death'

'amp_20q11.21' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S113. Gene #45: 'amp_20q11.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 45(20Q11.21) MUTATED	65	6	81
AMP PEAK 45(20Q11.21) WILD-TYPE	339	16	32

Figure S113. Get High-res Image Gene #45: 'amp_20q11.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_20q11.21' versus 'RESIDUAL_TUMOR'

P value = 0.046 (Fisher's exact test), Q value = 0.089

Table S114. Gene #45: 'amp_20q11.21' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 45(20Q11.21) MUTATED	93	5	9	13
AMP PEAK 45(20Q11.21) WILD-TYPE	278	17	7	27

Figure S114. Get High-res Image Gene #45: 'amp_20q11.21' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_20q13.12' versus 'Time to Death'

P value = 0.000346 (logrank test), Q value = 0.001

Table S115. Gene #46: 'amp_20q13.12' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 46(20Q13.12) MUTATED	151	40	0.1 - 225.5 (28.1)
AMP PEAK 46(20Q13.12) WILD-TYPE	386	50	0.1 - 185.8 (30.6)

Figure S115. Get High-res Image Gene #46: 'amp_20q13.12' versus Clinical Feature #1: 'Time to Death'

'amp_20q13.12' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S116. Gene #46: 'amp_20q13.12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 46(20Q13.12) MUTATED	67	7	78
AMP PEAK 46(20Q13.12) WILD-TYPE	337	15	35

Figure S116. Get High-res Image Gene #46: 'amp_20q13.12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_20q13.12' versus 'RESIDUAL_TUMOR'

P value = 0.0163 (Fisher's exact test), Q value = 0.036

Table S117. Gene #46: 'amp_20q13.12' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 46(20Q13.12) MUTATED	91	7	9	15
AMP PEAK 46(20Q13.12) WILD-TYPE	280	15	7	25

Figure S117. Get High-res Image Gene #46: 'amp_20q13.12' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_20q13.33' versus 'Time to Death'

P value = 0.00453 (logrank test), Q value = 0.011

Table S118. Gene #47: 'amp_20q13.33' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 47(20Q13.33) MUTATED	152	37	0.1 - 225.5 (28.0)
AMP PEAK 47(20Q13.33) WILD-TYPE	385	53	0.1 - 185.8 (30.1)

Figure S118. Get High-res Image Gene #47: 'amp_20q13.33' versus Clinical Feature #1: 'Time to Death'

'amp_20q13.33' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S119. Gene #47: 'amp_20q13.33' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 47(20Q13.33) MUTATED	70	6	77
AMP PEAK 47(20Q13.33) WILD-TYPE	334	16	36

Figure S119. Get High-res Image Gene #47: 'amp_20q13.33' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_20q13.33' versus 'RESIDUAL_TUMOR'

P value = 0.00257 (Fisher's exact test), Q value = 0.0066

Table S120. Gene #47: 'amp_20q13.33' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 47(20Q13.33) MUTATED	91	7	10	16
AMP PEAK 47(20Q13.33) WILD-TYPE	280	15	6	24

Figure S120. Get High-res Image Gene #47: 'amp_20q13.33' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_22q12.2' versus 'Time to Death'

P value = 0.000308 (logrank test), Q value = 0.00093

Table S121. Gene #48: 'amp_22q12.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 48(22Q12.2) MUTATED	61	20	0.4 - 225.5 (27.9)
AMP PEAK 48(22Q12.2) WILD-TYPE	476	70	0.1 - 185.8 (30.1)

Figure S121. Get High-res Image Gene #48: 'amp_22q12.2' versus Clinical Feature #1: 'Time to Death'

'amp_22q12.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S122. Gene #48: 'amp_22q12.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 48(22Q12.2) MUTATED	11	2	49
AMP PEAK 48(22Q12.2) WILD-TYPE	393	20	64

Figure S122. Get High-res Image Gene #48: 'amp_22q12.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_22q12.2' versus 'RESIDUAL_TUMOR'

P value = 0.00172 (Fisher's exact test), Q value = 0.0045

Table S123. Gene #48: 'amp_22q12.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 48(22Q12.2) MUTATED	35	3	7	6
AMP PEAK 48(22Q12.2) WILD-TYPE	336	19	9	34

Figure S123. Get High-res Image Gene #48: 'amp_22q12.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'amp_xp11.23' versus 'HISTOLOGICAL_TYPE'

P value = 0.00044 (Fisher's exact test), Q value = 0.0013

Table S124. Gene #49: 'amp_xp11.23' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 49(XP11.23) MUTATED	53	4	33
AMP PEAK 49(XP11.23) WILD-TYPE	351	18	80

Figure S124. Get High-res Image Gene #49: 'amp_xp11.23' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_xq28' versus 'Time to Death'

P value = 0.00767 (logrank test), Q value = 0.018

Table S125. Gene #50: 'amp_xq28' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
AMP PEAK 50(XQ28) MUTATED	92	24	0.1 - 110.6 (28.5)
AMP PEAK 50(XQ28) WILD-TYPE	445	66	0.1 - 225.5 (29.9)

Figure S125. Get High-res Image Gene #50: 'amp_xq28' versus Clinical Feature #1: 'Time to Death'

'amp_xq28' versus 'HISTOLOGICAL_TYPE'

P value = 0.00032 (Fisher's exact test), Q value = 0.00095

Table S126. Gene #50: 'amp_xq28' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
AMP PEAK 50(XQ28) MUTATED	55	4	34
AMP PEAK 50(XQ28) WILD-TYPE	349	18	79

Figure S126. Get High-res Image Gene #50: 'amp_xq28' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'amp_xq28' versus 'RESIDUAL_TUMOR'

P value = 0.158 (Fisher's exact test), Q value = 0.25

Table S127. Gene #50: 'amp_xq28' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
AMP PEAK 50(XQ28) MUTATED	65	2	6	8
AMP PEAK 50(XQ28) WILD-TYPE	306	20	10	32

Figure S127. Get High-res Image Gene #50: 'amp_xq28' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_1p36.21' versus 'Time to Death'

P value = 0.00987 (logrank test), Q value = 0.023

Table S128. Gene #51: 'del_1p36.21' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 1(1P36.21) MUTATED	71	20	0.6 - 149.6 (30.7)
DEL PEAK 1(1P36.21) WILD-TYPE	466	70	0.1 - 225.5 (29.8)

Figure S128. Get High-res Image Gene #51: 'del_1p36.21' versus Clinical Feature #1: 'Time to Death'

'del_1p36.21' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S129. Gene #51: 'del_1p36.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 1(1P36.21) MUTATED	28	5	38
DEL PEAK 1(1P36.21) WILD-TYPE	376	17	75

Figure S129. Get High-res Image Gene #51: 'del_1p36.21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_1p36.11' versus 'Time to Death'

P value = 0.000102 (logrank test), Q value = 0.00034

Table S130. Gene #52: 'del_1p36.11' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 2(1P36.11) MUTATED	82	25	0.6 - 149.6 (28.1)
DEL PEAK 2(1P36.11) WILD-TYPE	455	65	0.1 - 225.5 (30.1)

Figure S130. Get High-res Image Gene #52: 'del_1p36.11' versus Clinical Feature #1: 'Time to Death'

'del_1p36.11' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S131. Gene #52: 'del_1p36.11' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 2(1P36.11) MUTATED	28	5	50
DEL PEAK 2(1P36.11) WILD-TYPE	376	17	63

Figure S131. Get High-res Image Gene #52: 'del_1p36.11' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_1p36.11' versus 'RESIDUAL_TUMOR'

P value = 0.0498 (Fisher's exact test), Q value = 0.096

Table S132. Gene #52: 'del_1p36.11' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 2(1P36.11) MUTATED	53	7	5	6
DEL PEAK 2(1P36.11) WILD-TYPE	318	15	11	34

Figure S132. Get High-res Image Gene #52: 'del_1p36.11' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_2p25.3' versus 'Time to Death'

P value = 0.00503 (logrank test), Q value = 0.012

Table S133. Gene #53: 'del_2p25.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 3(2P25.3) MUTATED	25	8	0.6 - 125.4 (22.3)
DEL PEAK 3(2P25.3) WILD-TYPE	512	82	0.1 - 225.5 (30.1)

Figure S133. Get High-res Image Gene #53: 'del_2p25.3' versus Clinical Feature #1: 'Time to Death'

'del_2p25.3' versus 'RADIATION_THERAPY'

P value = 0.0899 (Fisher's exact test), Q value = 0.16

Table S134. Gene #53: 'del_2p25.3' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
DEL PEAK 3(2P25.3) MUTATED	17	6
DEL PEAK 3(2P25.3) WILD-TYPE	273	218

Figure S134. Get High-res Image Gene #53: 'del_2p25.3' versus Clinical Feature #2: 'RADIATION_THERAPY'

'del_2p25.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.00993 (Fisher's exact test), Q value = 0.023

Table S135. Gene #53: 'del_2p25.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 3(2P25.3) MUTATED	13	2	11
DEL PEAK 3(2P25.3) WILD-TYPE	391	20	102

Figure S135. Get High-res Image Gene #53: 'del_2p25.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_2q22.1' versus 'Time to Death'

P value = 8.17e-09 (logrank test), Q value = 3.3e-06

Table S136. Gene #54: 'del_2q22.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 4(2Q22.1) MUTATED	49	21	0.6 - 125.4 (22.4)
DEL PEAK 4(2Q22.1) WILD-TYPE	488	69	0.1 - 225.5 (30.6)

Figure S136. Get High-res Image Gene #54: 'del_2q22.1' versus Clinical Feature #1: 'Time to Death'

'del_2q22.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S137. Gene #54: 'del_2q22.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 4(2Q22.1) MUTATED	19	2	28
DEL PEAK 4(2Q22.1) WILD-TYPE	385	20	85

Figure S137. Get High-res Image Gene #54: 'del_2q22.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_2q22.1' versus 'RESIDUAL_TUMOR'

P value = 0.00014 (Fisher's exact test), Q value = 0.00045

Table S138. Gene #54: 'del_2q22.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 4(2Q22.1) MUTATED	24	2	5	10
DEL PEAK 4(2Q22.1) WILD-TYPE	347	20	11	30

Figure S138. Get High-res Image Gene #54: 'del_2q22.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_2q37.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.00026 (Fisher's exact test), Q value = 8e-04

Table S139. Gene #55: 'del_2q37.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 5(2Q37.3) MUTATED	27	2	23
DEL PEAK 5(2Q37.3) WILD-TYPE	377	20	90

Figure S139. Get High-res Image Gene #55: 'del_2q37.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_2q37.3' versus 'RESIDUAL_TUMOR'

P value = 0.0291 (Fisher's exact test), Q value = 0.06

Table S140. Gene #55: 'del_2q37.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 5(2Q37.3) MUTATED	32	2	3	9
DEL PEAK 5(2Q37.3) WILD-TYPE	339	20	13	31

Figure S140. Get High-res Image Gene #55: 'del_2q37.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_3p14.2' versus 'Time to Death'

P value = 0.00185 (logrank test), Q value = 0.0048

Table S141. Gene #56: 'del_3p14.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 6(3P14.2) MUTATED	78	21	0.1 - 125.4 (26.0)
DEL PEAK 6(3P14.2) WILD-TYPE	459	69	0.1 - 225.5 (30.4)

Figure S141. Get High-res Image Gene #56: 'del_3p14.2' versus Clinical Feature #1: 'Time to Death'

'del_3p14.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S142. Gene #56: 'del_3p14.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 6(3P14.2) MUTATED	29	6	44
DEL PEAK 6(3P14.2) WILD-TYPE	375	16	69

Figure S142. Get High-res Image Gene #56: 'del_3p14.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_3q13.31' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S143. Gene #57: 'del_3q13.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 7(3Q13.31) MUTATED	18	3	22
DEL PEAK 7(3Q13.31) WILD-TYPE	386	19	91

Figure S143. Get High-res Image Gene #57: 'del_3q13.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_4p16.3' versus 'Time to Death'

P value = 0.0235 (logrank test), Q value = 0.05

Table S144. Gene #58: 'del_4p16.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 8(4P16.3) MUTATED	93	22	0.2 - 149.6 (25.5)
DEL PEAK 8(4P16.3) WILD-TYPE	444	68	0.1 - 225.5 (31.0)

Figure S144. Get High-res Image Gene #58: 'del_4p16.3' versus Clinical Feature #1: 'Time to Death'

'del_4p16.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S145. Gene #58: 'del_4p16.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 8(4P16.3) MUTATED	32	6	56
DEL PEAK 8(4P16.3) WILD-TYPE	372	16	57

Figure S145. Get High-res Image Gene #58: 'del_4p16.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_4p15.31' versus 'Time to Death'

P value = 0.00572 (logrank test), Q value = 0.014

Table S146. Gene #59: 'del_4p15.31' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 9(4P15.31) MUTATED	98	25	0.2 - 149.6 (26.0)
DEL PEAK 9(4P15.31) WILD-TYPE	439	65	0.1 - 225.5 (30.7)

Figure S146. Get High-res Image Gene #59: 'del_4p15.31' versus Clinical Feature #1: 'Time to Death'

'del_4p15.31' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S147. Gene #59: 'del_4p15.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 9(4P15.31) MUTATED	35	5	59
DEL PEAK 9(4P15.31) WILD-TYPE	369	17	54

Figure S147. Get High-res Image Gene #59: 'del_4p15.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_4q22.1' versus 'Time to Death'

P value = 0.000117 (logrank test), Q value = 0.00038

Table S148. Gene #60: 'del_4q22.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 10(4Q22.1) MUTATED	105	32	0.2 - 149.6 (28.9)
DEL PEAK 10(4Q22.1) WILD-TYPE	432	58	0.1 - 225.5 (30.0)

Figure S148. Get High-res Image Gene #60: 'del_4q22.1' versus Clinical Feature #1: 'Time to Death'

'del_4q22.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S149. Gene #60: 'del_4q22.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 10(4Q22.1) MUTATED	33	6	67
DEL PEAK 10(4Q22.1) WILD-TYPE	371	16	46

Figure S149. Get High-res Image Gene #60: 'del_4q22.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_4q22.1' versus 'RESIDUAL_TUMOR'

P value = 0.0328 (Fisher's exact test), Q value = 0.066

Table S150. Gene #60: 'del_4q22.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 10(4Q22.1) MUTATED	64	6	7	10
DEL PEAK 10(4Q22.1) WILD-TYPE	307	16	9	30

Figure S150. Get High-res Image Gene #60: 'del_4q22.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_4q34.3' versus 'Time to Death'

P value = 0.000499 (logrank test), Q value = 0.0014

Table S151. Gene #61: 'del_4q34.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 11(4Q34.3) MUTATED	129	34	0.2 - 149.6 (27.9)
DEL PEAK 11(4Q34.3) WILD-TYPE	408	56	0.1 - 225.5 (30.7)

Figure S151. Get High-res Image Gene #61: 'del_4q34.3' versus Clinical Feature #1: 'Time to Death'

'del_4q34.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S152. Gene #61: 'del_4q34.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 11(4Q34.3) MUTATED	45	8	77
DEL PEAK 11(4Q34.3) WILD-TYPE	359	14	36

Figure S152. Get High-res Image Gene #61: 'del_4q34.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_4q34.3' versus 'RESIDUAL_TUMOR'

P value = 0.0891 (Fisher's exact test), Q value = 0.16

Table S153. Gene #61: 'del_4q34.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 11(4Q34.3) MUTATED	82	6	8	9
DEL PEAK 11(4Q34.3) WILD-TYPE	289	16	8	31

Figure S153. Get High-res Image Gene #61: 'del_4q34.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_5q12.1' versus 'Time to Death'

P value = 0.000214 (logrank test), Q value = 0.00066

Table S154. Gene #62: 'del_5q12.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 12(5Q12.1) MUTATED	110	31	0.2 - 149.6 (27.9)
DEL PEAK 12(5Q12.1) WILD-TYPE	427	59	0.1 - 225.5 (30.1)

Figure S154. Get High-res Image Gene #62: 'del_5q12.1' versus Clinical Feature #1: 'Time to Death'

'del_5q12.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S155. Gene #62: 'del_5q12.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 12(5Q12.1) MUTATED	37	4	70
DEL PEAK 12(5Q12.1) WILD-TYPE	367	18	43

Figure S155. Get High-res Image Gene #62: 'del_5q12.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_6q26' versus 'Time to Death'

P value = 0.123 (logrank test), Q value = 0.21

Table S156. Gene #63: 'del_6q26' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 13(6Q26) MUTATED	45	12	0.6 - 149.6 (33.3)
DEL PEAK 13(6Q26) WILD-TYPE	492	78	0.1 - 225.5 (29.8)

Figure S156. Get High-res Image Gene #63: 'del_6q26' versus Clinical Feature #1: 'Time to Death'

'del_6q26' versus 'RADIATION_THERAPY'

P value = 0.0347 (Fisher's exact test), Q value = 0.069

Table S157. Gene #63: 'del_6q26' versus Clinical Feature #2: 'RADIATION_THERAPY'

nPatients	NO	YES
ALL	290	224
DEL PEAK 13(6Q26) MUTATED	17	25
DEL PEAK 13(6Q26) WILD-TYPE	273	199

Figure S157. Get High-res Image Gene #63: 'del_6q26' versus Clinical Feature #2: 'RADIATION_THERAPY'

'del_6q26' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S158. Gene #63: 'del_6q26' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 13(6Q26) MUTATED	13	3	30
DEL PEAK 13(6Q26) WILD-TYPE	391	19	83

Figure S158. Get High-res Image Gene #63: 'del_6q26' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_7p22.3' versus 'Time to Death'

P value = 0.000786 (logrank test), Q value = 0.0022

Table S159. Gene #64: 'del_7p22.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 14(7P22.3) MUTATED	71	22	0.6 - 110.6 (30.1)
DEL PEAK 14(7P22.3) WILD-TYPE	466	68	0.1 - 225.5 (29.8)

Figure S159. Get High-res Image Gene #64: 'del_7p22.3' versus Clinical Feature #1: 'Time to Death'

'del_7p22.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S160. Gene #64: 'del_7p22.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 14(7P22.3) MUTATED	23	5	44
DEL PEAK 14(7P22.3) WILD-TYPE	381	17	69

Figure S160. Get High-res Image Gene #64: 'del_7p22.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_7p22.3' versus 'RESIDUAL_TUMOR'

P value = 0.119 (Fisher's exact test), Q value = 0.2

Table S161. Gene #64: 'del_7p22.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 14(7P22.3) MUTATED	46	4	4	9
DEL PEAK 14(7P22.3) WILD-TYPE	325	18	12	31

Figure S161. Get High-res Image Gene #64: 'del_7p22.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_7q11.22' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S162. Gene #65: 'del_7q11.22' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 15(7Q11.22) MUTATED	15	2	24
DEL PEAK 15(7Q11.22) WILD-TYPE	389	20	89

Figure S162. Get High-res Image Gene #65: 'del_7q11.22' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_7q31.1' versus 'Time to Death'

P value = 0.0218 (logrank test), Q value = 0.046

Table S163. Gene #66: 'del_7q31.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 16(7Q31.1) MUTATED	55	16	0.1 - 118.2 (27.0)
DEL PEAK 16(7Q31.1) WILD-TYPE	482	74	0.1 - 225.5 (29.9)

Figure S163. Get High-res Image Gene #66: 'del_7q31.1' versus Clinical Feature #1: 'Time to Death'

'del_7q31.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S164. Gene #66: 'del_7q31.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 16(7Q31.1) MUTATED	12	3	40
DEL PEAK 16(7Q31.1) WILD-TYPE	392	19	73

Figure S164. Get High-res Image Gene #66: 'del_7q31.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_7q31.1' versus 'RESIDUAL_TUMOR'

P value = 0.145 (Fisher's exact test), Q value = 0.23

Table S165. Gene #66: 'del_7q31.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 16(7Q31.1) MUTATED	37	2	3	8
DEL PEAK 16(7Q31.1) WILD-TYPE	334	20	13	32

Figure S165. Get High-res Image Gene #66: 'del_7q31.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_7q36.1' versus 'Time to Death'

P value = 0.00254 (logrank test), Q value = 0.0065

Table S166. Gene #67: 'del_7q36.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 17(7Q36.1) MUTATED	63	21	1.8 - 125.4 (32.0)
DEL PEAK 17(7Q36.1) WILD-TYPE	474	69	0.1 - 225.5 (29.7)

Figure S166. Get High-res Image Gene #67: 'del_7q36.1' versus Clinical Feature #1: 'Time to Death'

'del_7q36.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S167. Gene #67: 'del_7q36.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 17(7Q36.1) MUTATED	13	4	46
DEL PEAK 17(7Q36.1) WILD-TYPE	391	18	67

Figure S167. Get High-res Image Gene #67: 'del_7q36.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_8p23.2' versus 'Time to Death'

P value = 1.25e-05 (logrank test), Q value = 5e-05

Table S168. Gene #68: 'del_8p23.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 18(8P23.2) MUTATED	117	35	0.3 - 225.5 (27.4)
DEL PEAK 18(8P23.2) WILD-TYPE	420	55	0.1 - 185.8 (30.7)

Figure S168. Get High-res Image Gene #68: 'del_8p23.2' versus Clinical Feature #1: 'Time to Death'

'del_8p23.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S169. Gene #68: 'del_8p23.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 18(8P23.2) MUTATED	36	6	77
DEL PEAK 18(8P23.2) WILD-TYPE	368	16	36

Figure S169. Get High-res Image Gene #68: 'del_8p23.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_8p23.2' versus 'RESIDUAL_TUMOR'

P value = 0.0316 (Fisher's exact test), Q value = 0.064

Table S170. Gene #68: 'del_8p23.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 18(8P23.2) MUTATED	71	5	7	13
DEL PEAK 18(8P23.2) WILD-TYPE	300	17	9	27

Figure S170. Get High-res Image Gene #68: 'del_8p23.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_8p21.2' versus 'Time to Death'

P value = 0.000314 (logrank test), Q value = 0.00094

Table S171. Gene #69: 'del_8p21.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 19(8P21.2) MUTATED	116	33	0.3 - 225.5 (27.6)
DEL PEAK 19(8P21.2) WILD-TYPE	421	57	0.1 - 185.8 (30.7)

Figure S171. Get High-res Image Gene #69: 'del_8p21.2' versus Clinical Feature #1: 'Time to Death'

'del_8p21.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S172. Gene #69: 'del_8p21.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 19(8P21.2) MUTATED	28	7	82
DEL PEAK 19(8P21.2) WILD-TYPE	376	15	31

Figure S172. Get High-res Image Gene #69: 'del_8p21.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_8p21.2' versus 'RESIDUAL_TUMOR'

P value = 0.0867 (Fisher's exact test), Q value = 0.16

Table S173. Gene #69: 'del_8p21.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 19(8P21.2) MUTATED	72	5	7	11
DEL PEAK 19(8P21.2) WILD-TYPE	299	17	9	29

Figure S173. Get High-res Image Gene #69: 'del_8p21.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_9p23' versus 'Time to Death'

P value = 0.000841 (logrank test), Q value = 0.0023

Table S174. Gene #70: 'del_9p23' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 20(9P23) MUTATED	80	24	0.3 - 149.6 (27.0)
DEL PEAK 20(9P23) WILD-TYPE	457	66	0.1 - 225.5 (30.1)

Figure S174. Get High-res Image Gene #70: 'del_9p23' versus Clinical Feature #1: 'Time to Death'

'del_9p23' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S175. Gene #70: 'del_9p23' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 20(9P23) MUTATED	30	4	46
DEL PEAK 20(9P23) WILD-TYPE	374	18	67

Figure S175. Get High-res Image Gene #70: 'del_9p23' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_9q21.2' versus 'Time to Death'

P value = 5.69e-06 (logrank test), Q value = 4e-05

Table S176. Gene #71: 'del_9q21.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 21(9Q21.2) MUTATED	129	39	0.1 - 136.6 (27.2)
DEL PEAK 21(9Q21.2) WILD-TYPE	408	51	0.1 - 225.5 (30.7)

Figure S176. Get High-res Image Gene #71: 'del_9q21.2' versus Clinical Feature #1: 'Time to Death'

'del_9q21.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S177. Gene #71: 'del_9q21.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 21(9Q21.2) MUTATED	51	10	68
DEL PEAK 21(9Q21.2) WILD-TYPE	353	12	45

Figure S177. Get High-res Image Gene #71: 'del_9q21.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_9q21.2' versus 'RESIDUAL_TUMOR'

P value = 0.102 (Fisher's exact test), Q value = 0.18

Table S178. Gene #71: 'del_9q21.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 21(9Q21.2) MUTATED	80	5	7	13
DEL PEAK 21(9Q21.2) WILD-TYPE	291	17	9	27

Figure S178. Get High-res Image Gene #71: 'del_9q21.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_9q34.2' versus 'Time to Death'

P value = 3.37e-05 (logrank test), Q value = 0.00012

Table S179. Gene #72: 'del_9q34.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 22(9Q34.2) MUTATED	131	39	0.2 - 136.6 (28.6)
DEL PEAK 22(9Q34.2) WILD-TYPE	406	51	0.1 - 225.5 (30.1)

Figure S179. Get High-res Image Gene #72: 'del_9q34.2' versus Clinical Feature #1: 'Time to Death'

'del_9q34.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S180. Gene #72: 'del_9q34.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 22(9Q34.2) MUTATED	55	10	67
DEL PEAK 22(9Q34.2) WILD-TYPE	349	12	46

Figure S180. Get High-res Image Gene #72: 'del_9q34.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_9q34.2' versus 'RESIDUAL_TUMOR'

P value = 0.0712 (Fisher's exact test), Q value = 0.13

Table S181. Gene #72: 'del_9q34.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 22(9Q34.2) MUTATED	80	5	6	15
DEL PEAK 22(9Q34.2) WILD-TYPE	291	17	10	25

Figure S181. Get High-res Image Gene #72: 'del_9q34.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_10q21.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S182. Gene #73: 'del_10q21.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 23(10Q21.1) MUTATED	16	4	30
DEL PEAK 23(10Q21.1) WILD-TYPE	388	18	83

Figure S182. Get High-res Image Gene #73: 'del_10q21.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_10q23.31' versus 'Time to Death'

P value = 0.000184 (logrank test), Q value = 0.00058

Table S183. Gene #74: 'del_10q23.31' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 24(10Q23.31) MUTATED	77	23	0.3 - 125.4 (23.9)
DEL PEAK 24(10Q23.31) WILD-TYPE	460	67	0.1 - 225.5 (31.1)

Figure S183. Get High-res Image Gene #74: 'del_10q23.31' versus Clinical Feature #1: 'Time to Death'

'del_10q23.31' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S184. Gene #74: 'del_10q23.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 24(10Q23.31) MUTATED	32	6	40
DEL PEAK 24(10Q23.31) WILD-TYPE	372	16	73

Figure S184. Get High-res Image Gene #74: 'del_10q23.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_10q23.31' versus 'RESIDUAL_TUMOR'

P value = 0.121 (Fisher's exact test), Q value = 0.2

Table S185. Gene #74: 'del_10q23.31' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 24(10Q23.31) MUTATED	48	2	5	8
DEL PEAK 24(10Q23.31) WILD-TYPE	323	20	11	32

Figure S185. Get High-res Image Gene #74: 'del_10q23.31' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_11p15.5' versus 'Time to Death'

P value = 0.000665 (logrank test), Q value = 0.0019

Table S186. Gene #75: 'del_11p15.5' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 25(11P15.5) MUTATED	103	29	0.1 - 149.6 (28.1)
DEL PEAK 25(11P15.5) WILD-TYPE	434	61	0.1 - 225.5 (30.1)

Figure S186. Get High-res Image Gene #75: 'del_11p15.5' versus Clinical Feature #1: 'Time to Death'

'del_11p15.5' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S187. Gene #75: 'del_11p15.5' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 25(11P15.5) MUTATED	40	6	58
DEL PEAK 25(11P15.5) WILD-TYPE	364	16	55

Figure S187. Get High-res Image Gene #75: 'del_11p15.5' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_11p15.5' versus 'RESIDUAL_TUMOR'

P value = 0.0269 (Fisher's exact test), Q value = 0.056

Table S188. Gene #75: 'del_11p15.5' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 25(11P15.5) MUTATED	63	3	7	11
DEL PEAK 25(11P15.5) WILD-TYPE	308	19	9	29

Figure S188. Get High-res Image Gene #75: 'del_11p15.5' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_11q14.1' versus 'Time to Death'

P value = 0.00663 (logrank test), Q value = 0.016

Table S189. Gene #76: 'del_11q14.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 26(11Q14.1) MUTATED	69	18	0.3 - 136.6 (23.9)
DEL PEAK 26(11Q14.1) WILD-TYPE	468	72	0.1 - 225.5 (30.7)

Figure S189. Get High-res Image Gene #76: 'del_11q14.1' versus Clinical Feature #1: 'Time to Death'

'del_11q14.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S190. Gene #76: 'del_11q14.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 26(11Q14.1) MUTATED	21	6	42
DEL PEAK 26(11Q14.1) WILD-TYPE	383	16	71

Figure S190. Get High-res Image Gene #76: 'del_11q14.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_11q25' versus 'Time to Death'

P value = 0.000197 (logrank test), Q value = 0.00062

Table S191. Gene #77: 'del_11q25' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 27(11Q25) MUTATED	94	26	0.3 - 136.6 (24.0)
DEL PEAK 27(11Q25) WILD-TYPE	443	64	0.1 - 225.5 (30.7)

Figure S191. Get High-res Image Gene #77: 'del_11q25' versus Clinical Feature #1: 'Time to Death'

'del_11q25' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S192. Gene #77: 'del_11q25' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 27(11Q25) MUTATED	33	6	55
DEL PEAK 27(11Q25) WILD-TYPE	371	16	58

Figure S192. Get High-res Image Gene #77: 'del_11q25' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_12q23.1' versus 'Time to Death'

P value = 6.25e-05 (logrank test), Q value = 0.00022

Table S193. Gene #78: 'del_12q23.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 28(12Q23.1) MUTATED	56	19	0.6 - 118.2 (23.9)
DEL PEAK 28(12Q23.1) WILD-TYPE	481	71	0.1 - 225.5 (30.7)

Figure S193. Get High-res Image Gene #78: 'del_12q23.1' versus Clinical Feature #1: 'Time to Death'

'del_12q23.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S194. Gene #78: 'del_12q23.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 28(12Q23.1) MUTATED	14	3	39
DEL PEAK 28(12Q23.1) WILD-TYPE	390	19	74

Figure S194. Get High-res Image Gene #78: 'del_12q23.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_12q23.1' versus 'RESIDUAL_TUMOR'

P value = 0.0125 (Fisher's exact test), Q value = 0.028

Table S195. Gene #78: 'del_12q23.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 28(12Q23.1) MUTATED	34	1	4	9
DEL PEAK 28(12Q23.1) WILD-TYPE	337	21	12	31

Figure S195. Get High-res Image Gene #78: 'del_12q23.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_12q24.33' versus 'Time to Death'

P value = 0.00307 (logrank test), Q value = 0.0077

Table S196. Gene #79: 'del_12q24.33' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 29(12Q24.33) MUTATED	66	18	0.1 - 118.2 (25.0)
DEL PEAK 29(12Q24.33) WILD-TYPE	471	72	0.1 - 225.5 (30.7)

Figure S196. Get High-res Image Gene #79: 'del_12q24.33' versus Clinical Feature #1: 'Time to Death'

'del_12q24.33' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S197. Gene #79: 'del_12q24.33' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 29(12Q24.33) MUTATED	20	2	44
DEL PEAK 29(12Q24.33) WILD-TYPE	384	20	69

Figure S197. Get High-res Image Gene #79: 'del_12q24.33' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_12q24.33' versus 'RESIDUAL_TUMOR'

P value = 0.00903 (Fisher's exact test), Q value = 0.021

Table S198. Gene #79: 'del_12q24.33' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 29(12Q24.33) MUTATED	40	2	5	10
DEL PEAK 29(12Q24.33) WILD-TYPE	331	20	11	30

Figure S198. Get High-res Image Gene #79: 'del_12q24.33' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_13q11' versus 'Time to Death'

P value = 0.00144 (logrank test), Q value = 0.0039

Table S199. Gene #80: 'del_13q11' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 30(13Q11) MUTATED	97	27	0.1 - 149.6 (26.4)
DEL PEAK 30(13Q11) WILD-TYPE	440	63	0.1 - 225.5 (30.6)

Figure S199. Get High-res Image Gene #80: 'del_13q11' versus Clinical Feature #1: 'Time to Death'

'del_13q11' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S200. Gene #80: 'del_13q11' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 30(13Q11) MUTATED	41	6	51
DEL PEAK 30(13Q11) WILD-TYPE	363	16	62

Figure S200. Get High-res Image Gene #80: 'del_13q11' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_13q14.2' versus 'Time to Death'

P value = 0.00016 (logrank test), Q value = 0.00051

Table S201. Gene #81: 'del_13q14.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 31(13Q14.2) MUTATED	105	29	0.1 - 149.6 (25.9)
DEL PEAK 31(13Q14.2) WILD-TYPE	432	61	0.1 - 225.5 (31.1)

Figure S201. Get High-res Image Gene #81: 'del_13q14.2' versus Clinical Feature #1: 'Time to Death'

'del_13q14.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S202. Gene #81: 'del_13q14.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 31(13Q14.2) MUTATED	54	7	45
DEL PEAK 31(13Q14.2) WILD-TYPE	350	15	68

Figure S202. Get High-res Image Gene #81: 'del_13q14.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_14q13.1' versus 'Time to Death'

P value = 0.00158 (logrank test), Q value = 0.0042

Table S203. Gene #82: 'del_14q13.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 32(14Q13.1) MUTATED	73	19	0.1 - 125.4 (22.5)
DEL PEAK 32(14Q13.1) WILD-TYPE	464	71	0.1 - 225.5 (30.7)

Figure S203. Get High-res Image Gene #82: 'del_14q13.1' versus Clinical Feature #1: 'Time to Death'

'del_14q13.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S204. Gene #82: 'del_14q13.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 32(14Q13.1) MUTATED	26	5	42
DEL PEAK 32(14Q13.1) WILD-TYPE	378	17	71

Figure S204. Get High-res Image Gene #82: 'del_14q13.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_15q15.1' versus 'Time to Death'

P value = 7e-05 (logrank test), Q value = 0.00024

Table S205. Gene #83: 'del_15q15.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 33(15Q15.1) MUTATED	139	37	0.1 - 136.6 (26.4)
DEL PEAK 33(15Q15.1) WILD-TYPE	398	53	0.1 - 225.5 (32.0)

Figure S205. Get High-res Image Gene #83: 'del_15q15.1' versus Clinical Feature #1: 'Time to Death'

'del_15q15.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S206. Gene #83: 'del_15q15.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 33(15Q15.1) MUTATED	54	10	76
DEL PEAK 33(15Q15.1) WILD-TYPE	350	12	37

Figure S206. Get High-res Image Gene #83: 'del_15q15.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_15q15.1' versus 'RESIDUAL_TUMOR'

P value = 0.0559 (Fisher's exact test), Q value = 0.11

Table S207. Gene #83: 'del_15q15.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 33(15Q15.1) MUTATED	86	7	7	15
DEL PEAK 33(15Q15.1) WILD-TYPE	285	15	9	25

Figure S207. Get High-res Image Gene #83: 'del_15q15.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_15q23' versus 'Time to Death'

P value = 0.00675 (logrank test), Q value = 0.016

Table S208. Gene #84: 'del_15q23' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 34(15Q23) MUTATED	115	26	0.2 - 136.6 (22.6)
DEL PEAK 34(15Q23) WILD-TYPE	422	64	0.1 - 225.5 (32.7)

Figure S208. Get High-res Image Gene #84: 'del_15q23' versus Clinical Feature #1: 'Time to Death'

'del_15q23' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S209. Gene #84: 'del_15q23' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 34(15Q23) MUTATED	38	8	69
DEL PEAK 34(15Q23) WILD-TYPE	366	14	44

Figure S209. Get High-res Image Gene #84: 'del_15q23' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_16p13.3' versus 'Time to Death'

P value = 4.95e-05 (logrank test), Q value = 0.00018

Table S210. Gene #85: 'del_16p13.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 35(16P13.3) MUTATED	91	27	0.1 - 125.4 (27.1)
DEL PEAK 35(16P13.3) WILD-TYPE	446	63	0.1 - 225.5 (30.9)

Figure S210. Get High-res Image Gene #85: 'del_16p13.3' versus Clinical Feature #1: 'Time to Death'

'del_16p13.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S211. Gene #85: 'del_16p13.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 35(16P13.3) MUTATED	27	5	60
DEL PEAK 35(16P13.3) WILD-TYPE	377	17	53

Figure S211. Get High-res Image Gene #85: 'del_16p13.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_16q21' versus 'Time to Death'

P value = 0.00204 (logrank test), Q value = 0.0053

Table S212. Gene #86: 'del_16q21' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 36(16Q21) MUTATED	153	37	0.1 - 123.7 (27.9)
DEL PEAK 36(16Q21) WILD-TYPE	384	53	0.1 - 225.5 (31.0)

Figure S212. Get High-res Image Gene #86: 'del_16q21' versus Clinical Feature #1: 'Time to Death'

'del_16q21' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S213. Gene #86: 'del_16q21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 36(16Q21) MUTATED	65	9	80
DEL PEAK 36(16Q21) WILD-TYPE	339	13	33

Figure S213. Get High-res Image Gene #86: 'del_16q21' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_16q22.3' versus 'Time to Death'

P value = 0.0207 (logrank test), Q value = 0.044

Table S214. Gene #87: 'del_16q22.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 37(16Q22.3) MUTATED	157	34	0.1 - 123.7 (27.2)
DEL PEAK 37(16Q22.3) WILD-TYPE	380	56	0.1 - 225.5 (31.1)

Figure S214. Get High-res Image Gene #87: 'del_16q22.3' versus Clinical Feature #1: 'Time to Death'

'del_16q22.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S215. Gene #87: 'del_16q22.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 37(16Q22.3) MUTATED	69	9	80
DEL PEAK 37(16Q22.3) WILD-TYPE	335	13	33

Figure S215. Get High-res Image Gene #87: 'del_16q22.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_16q23.1' versus 'Time to Death'

P value = 0.00123 (logrank test), Q value = 0.0033

Table S216. Gene #88: 'del_16q23.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 38(16Q23.1) MUTATED	165	39	0.1 - 123.7 (27.3)
DEL PEAK 38(16Q23.1) WILD-TYPE	372	51	0.1 - 225.5 (31.2)

Figure S216. Get High-res Image Gene #88: 'del_16q23.1' versus Clinical Feature #1: 'Time to Death'

'del_16q23.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S217. Gene #88: 'del_16q23.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 38(16Q23.1) MUTATED	71	8	87
DEL PEAK 38(16Q23.1) WILD-TYPE	333	14	26

Figure S217. Get High-res Image Gene #88: 'del_16q23.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_16q23.1' versus 'RESIDUAL_TUMOR'

P value = 0.0304 (Fisher's exact test), Q value = 0.062

Table S218. Gene #88: 'del_16q23.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 38(16Q23.1) MUTATED	105	8	10	14
DEL PEAK 38(16Q23.1) WILD-TYPE	266	14	6	26

Figure S218. Get High-res Image Gene #88: 'del_16q23.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_17p13.3' versus 'Time to Death'

P value = 1.07e-06 (logrank test), Q value = 4e-05

Table S219. Gene #89: 'del_17p13.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 39(17P13.3) MUTATED	121	37	0.1 - 136.6 (27.1)
DEL PEAK 39(17P13.3) WILD-TYPE	416	53	0.1 - 225.5 (30.7)

Figure S219. Get High-res Image Gene #89: 'del_17p13.3' versus Clinical Feature #1: 'Time to Death'

'del_17p13.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S220. Gene #89: 'del_17p13.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 39(17P13.3) MUTATED	48	9	65
DEL PEAK 39(17P13.3) WILD-TYPE	356	13	48

Figure S220. Get High-res Image Gene #89: 'del_17p13.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_17p13.3' versus 'RESIDUAL_TUMOR'

P value = 0.0807 (Fisher's exact test), Q value = 0.15

Table S221. Gene #89: 'del_17p13.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 39(17P13.3) MUTATED	73	7	4	14
DEL PEAK 39(17P13.3) WILD-TYPE	298	15	12	26

Figure S221. Get High-res Image Gene #89: 'del_17p13.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_17p11.2' versus 'Time to Death'

P value = 5.76e-06 (logrank test), Q value = 4e-05

Table S222. Gene #90: 'del_17p11.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 40(17P11.2) MUTATED	127	38	0.1 - 136.6 (27.9)
DEL PEAK 40(17P11.2) WILD-TYPE	410	52	0.1 - 225.5 (30.1)

Figure S222. Get High-res Image Gene #90: 'del_17p11.2' versus Clinical Feature #1: 'Time to Death'

'del_17p11.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S223. Gene #90: 'del_17p11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 40(17P11.2) MUTATED	48	9	71
DEL PEAK 40(17P11.2) WILD-TYPE	356	13	42

Figure S223. Get High-res Image Gene #90: 'del_17p11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_17q11.2' versus 'Time to Death'

P value = 0.000896 (logrank test), Q value = 0.0025

Table S224. Gene #91: 'del_17q11.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 41(17Q11.2) MUTATED	104	29	0.2 - 136.6 (28.0)
DEL PEAK 41(17Q11.2) WILD-TYPE	433	61	0.1 - 225.5 (30.1)

Figure S224. Get High-res Image Gene #91: 'del_17q11.2' versus Clinical Feature #1: 'Time to Death'

'del_17q11.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S225. Gene #91: 'del_17q11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 41(17Q11.2) MUTATED	46	5	54
DEL PEAK 41(17Q11.2) WILD-TYPE	358	17	59

Figure S225. Get High-res Image Gene #91: 'del_17q11.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_17q11.2' versus 'RESIDUAL_TUMOR'

P value = 0.115 (Fisher's exact test), Q value = 0.2

Table S226. Gene #91: 'del_17q11.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 41(17Q11.2) MUTATED	66	6	6	10
DEL PEAK 41(17Q11.2) WILD-TYPE	305	16	10	30

Figure S226. Get High-res Image Gene #91: 'del_17q11.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_17q21.31' versus 'Time to Death'

P value = 0.00013 (logrank test), Q value = 0.00042

Table S227. Gene #92: 'del_17q21.31' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 42(17Q21.31) MUTATED	113	33	0.2 - 136.6 (27.3)
DEL PEAK 42(17Q21.31) WILD-TYPE	424	57	0.1 - 225.5 (30.7)

Figure S227. Get High-res Image Gene #92: 'del_17q21.31' versus Clinical Feature #1: 'Time to Death'

'del_17q21.31' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S228. Gene #92: 'del_17q21.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 42(17Q21.31) MUTATED	47	6	61
DEL PEAK 42(17Q21.31) WILD-TYPE	357	16	52

Figure S228. Get High-res Image Gene #92: 'del_17q21.31' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_17q21.31' versus 'RESIDUAL_TUMOR'

P value = 0.0206 (Fisher's exact test), Q value = 0.044

Table S229. Gene #92: 'del_17q21.31' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 42(17Q21.31) MUTATED	68	6	6	14
DEL PEAK 42(17Q21.31) WILD-TYPE	303	16	10	26

Figure S229. Get High-res Image Gene #92: 'del_17q21.31' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_18q21.2' versus 'Time to Death'

P value = 0.0899 (logrank test), Q value = 0.16

Table S230. Gene #93: 'del_18q21.2' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 43(18Q21.2) MUTATED	89	20	0.1 - 136.6 (28.1)
DEL PEAK 43(18Q21.2) WILD-TYPE	448	70	0.1 - 225.5 (30.1)

Figure S230. Get High-res Image Gene #93: 'del_18q21.2' versus Clinical Feature #1: 'Time to Death'

'del_18q21.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S231. Gene #93: 'del_18q21.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 43(18Q21.2) MUTATED	38	6	46
DEL PEAK 43(18Q21.2) WILD-TYPE	366	16	67

Figure S231. Get High-res Image Gene #93: 'del_18q21.2' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_18q21.2' versus 'RESIDUAL_TUMOR'

P value = 0.0378 (Fisher's exact test), Q value = 0.075

Table S232. Gene #93: 'del_18q21.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 43(18Q21.2) MUTATED	50	5	5	10
DEL PEAK 43(18Q21.2) WILD-TYPE	321	17	11	30

Figure S232. Get High-res Image Gene #93: 'del_18q21.2' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_18q23' versus 'Time to Death'

P value = 0.00106 (logrank test), Q value = 0.0029

Table S233. Gene #94: 'del_18q23' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 44(18Q23) MUTATED	97	26	0.1 - 136.6 (28.1)
DEL PEAK 44(18Q23) WILD-TYPE	440	64	0.1 - 225.5 (30.1)

Figure S233. Get High-res Image Gene #94: 'del_18q23' versus Clinical Feature #1: 'Time to Death'

'del_18q23' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S234. Gene #94: 'del_18q23' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 44(18Q23) MUTATED	39	6	53
DEL PEAK 44(18Q23) WILD-TYPE	365	16	60

Figure S234. Get High-res Image Gene #94: 'del_18q23' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_18q23' versus 'RESIDUAL_TUMOR'

P value = 0.00535 (Fisher's exact test), Q value = 0.013

Table S235. Gene #94: 'del_18q23' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 44(18Q23) MUTATED	57	5	8	9
DEL PEAK 44(18Q23) WILD-TYPE	314	17	8	31

Figure S235. Get High-res Image Gene #94: 'del_18q23' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_19p13.3' versus 'Time to Death'

P value = 5.21e-07 (logrank test), Q value = 4e-05

Table S236. Gene #95: 'del_19p13.3' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 45(19P13.3) MUTATED	156	46	0.1 - 136.6 (27.6)
DEL PEAK 45(19P13.3) WILD-TYPE	381	44	0.1 - 225.5 (30.7)

Figure S236. Get High-res Image Gene #95: 'del_19p13.3' versus Clinical Feature #1: 'Time to Death'

'del_19p13.3' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S237. Gene #95: 'del_19p13.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 45(19P13.3) MUTATED	45	10	102
DEL PEAK 45(19P13.3) WILD-TYPE	359	12	11

Figure S237. Get High-res Image Gene #95: 'del_19p13.3' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_19p13.3' versus 'RESIDUAL_TUMOR'

P value = 0.00313 (Fisher's exact test), Q value = 0.0078

Table S238. Gene #95: 'del_19p13.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 45(19P13.3) MUTATED	94	9	10	15
DEL PEAK 45(19P13.3) WILD-TYPE	277	13	6	25

Figure S238. Get High-res Image Gene #95: 'del_19p13.3' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_19p12' versus 'Time to Death'

P value = 0.0946 (logrank test), Q value = 0.17

Table S239. Gene #96: 'del_19p12' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 46(19P12) MUTATED	58	14	0.2 - 136.6 (29.0)
DEL PEAK 46(19P12) WILD-TYPE	479	76	0.1 - 225.5 (30.0)

Figure S239. Get High-res Image Gene #96: 'del_19p12' versus Clinical Feature #1: 'Time to Death'

'del_19p12' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S240. Gene #96: 'del_19p12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 46(19P12) MUTATED	21	5	32
DEL PEAK 46(19P12) WILD-TYPE	383	17	81

Figure S240. Get High-res Image Gene #96: 'del_19p12' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_19p12' versus 'RESIDUAL_TUMOR'

P value = 0.112 (Fisher's exact test), Q value = 0.19

Table S241. Gene #96: 'del_19p12' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 46(19P12) MUTATED	33	3	2	8
DEL PEAK 46(19P12) WILD-TYPE	338	19	14	32

Figure S241. Get High-res Image Gene #96: 'del_19p12' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_19q13.43' versus 'Time to Death'

P value = 0.00293 (logrank test), Q value = 0.0074

Table S242. Gene #97: 'del_19q13.43' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 47(19Q13.43) MUTATED	66	19	0.1 - 125.4 (25.8)
DEL PEAK 47(19Q13.43) WILD-TYPE	471	71	0.1 - 225.5 (30.1)

Figure S242. Get High-res Image Gene #97: 'del_19q13.43' versus Clinical Feature #1: 'Time to Death'

'del_19q13.43' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S243. Gene #97: 'del_19q13.43' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 47(19Q13.43) MUTATED	20	4	43
DEL PEAK 47(19Q13.43) WILD-TYPE	384	18	70

Figure S243. Get High-res Image Gene #97: 'del_19q13.43' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_19q13.43' versus 'RESIDUAL_TUMOR'

P value = 0.0175 (Fisher's exact test), Q value = 0.039

Table S244. Gene #97: 'del_19q13.43' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 47(19Q13.43) MUTATED	37	6	3	8
DEL PEAK 47(19Q13.43) WILD-TYPE	334	16	13	32

Figure S244. Get High-res Image Gene #97: 'del_19q13.43' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_20p12.1' versus 'Time to Death'

P value = 0.000108 (logrank test), Q value = 0.00035

Table S245. Gene #98: 'del_20p12.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 48(20P12.1) MUTATED	35	14	0.3 - 149.6 (27.6)
DEL PEAK 48(20P12.1) WILD-TYPE	502	76	0.1 - 225.5 (30.1)

Figure S245. Get High-res Image Gene #98: 'del_20p12.1' versus Clinical Feature #1: 'Time to Death'

'del_20p12.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-04 (Fisher's exact test), Q value = 0.00034

Table S246. Gene #98: 'del_20p12.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 48(20P12.1) MUTATED	16	1	18
DEL PEAK 48(20P12.1) WILD-TYPE	388	21	95

Figure S246. Get High-res Image Gene #98: 'del_20p12.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_20p12.1' versus 'RESIDUAL_TUMOR'

P value = 0.153 (Fisher's exact test), Q value = 0.24

Table S247. Gene #98: 'del_20p12.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 48(20P12.1) MUTATED	20	1	2	5
DEL PEAK 48(20P12.1) WILD-TYPE	351	21	14	35

Figure S247. Get High-res Image Gene #98: 'del_20p12.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_22q12.1' versus 'Time to Death'

P value = 0.00109 (logrank test), Q value = 0.003

Table S248. Gene #99: 'del_22q12.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 49(22Q12.1) MUTATED	94	26	0.1 - 136.6 (28.6)
DEL PEAK 49(22Q12.1) WILD-TYPE	443	64	0.1 - 225.5 (29.9)

Figure S248. Get High-res Image Gene #99: 'del_22q12.1' versus Clinical Feature #1: 'Time to Death'

'del_22q12.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S249. Gene #99: 'del_22q12.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 49(22Q12.1) MUTATED	48	9	38
DEL PEAK 49(22Q12.1) WILD-TYPE	356	13	75

Figure S249. Get High-res Image Gene #99: 'del_22q12.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_22q12.1' versus 'RESIDUAL_TUMOR'

P value = 0.129 (Fisher's exact test), Q value = 0.21

Table S250. Gene #99: 'del_22q12.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 49(22Q12.1) MUTATED	59	5	3	12
DEL PEAK 49(22Q12.1) WILD-TYPE	312	17	13	28

Figure S250. Get High-res Image Gene #99: 'del_22q12.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

'del_22q13.32' versus 'Time to Death'

P value = 2.75e-05 (logrank test), Q value = 0.00011

Table S251. Gene #100: 'del_22q13.32' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 50(22Q13.32) MUTATED	139	38	0.1 - 136.6 (27.1)
DEL PEAK 50(22Q13.32) WILD-TYPE	398	52	0.1 - 225.5 (30.7)

Figure S251. Get High-res Image Gene #100: 'del_22q13.32' versus Clinical Feature #1: 'Time to Death'

'del_22q13.32' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S252. Gene #100: 'del_22q13.32' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 50(22Q13.32) MUTATED	57	10	73
DEL PEAK 50(22Q13.32) WILD-TYPE	347	12	40

Figure S252. Get High-res Image Gene #100: 'del_22q13.32' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_xp21.1' versus 'Time to Death'

P value = 7.7e-06 (logrank test), Q value = 4e-05

Table S253. Gene #101: 'del_xp21.1' versus Clinical Feature #1: 'Time to Death'

	nPatients	nDeath	Duration Range (Median), Month
ALL	537	90	0.1 - 225.5 (29.9)
DEL PEAK 51(XP21.1) MUTATED	87	29	0.3 - 118.2 (27.3)
DEL PEAK 51(XP21.1) WILD-TYPE	450	61	0.1 - 225.5 (30.6)

Figure S253. Get High-res Image Gene #101: 'del_xp21.1' versus Clinical Feature #1: 'Time to Death'

'del_xp21.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 4e-05

Table S254. Gene #101: 'del_xp21.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

nPatients	ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA	MIXED SEROUS AND ENDOMETRIOID	SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL	404	22	113
DEL PEAK 51(XP21.1) MUTATED	32	4	52
DEL PEAK 51(XP21.1) WILD-TYPE	372	18	61

Figure S254. Get High-res Image Gene #101: 'del_xp21.1' versus Clinical Feature #3: 'HISTOLOGICAL_TYPE'

'del_xp21.1' versus 'RESIDUAL_TUMOR'

P value = 0.111 (Fisher's exact test), Q value = 0.19

Table S255. Gene #101: 'del_xp21.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

nPatients	R0	R1	R2	RX
ALL	371	22	16	40
DEL PEAK 51(XP21.1) MUTATED	56	2	6	7
DEL PEAK 51(XP21.1) WILD-TYPE	315	20	10	33

Figure S255. Get High-res Image Gene #101: 'del_xp21.1' versus Clinical Feature #4: 'RESIDUAL_TUMOR'

Methods & Data

Input

Copy number data file = all_lesions.txt from GISTIC pipeline
Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/UCEC-TP/22534122/transformed.cor.cli.txt
Clinical data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/Append_Data/UCEC-TP/22507145/UCEC-TP.merged_data.txt
Number of patients = 539
Number of significantly focal cnvs = 101
Number of selected clinical features = 4
Exclude genes that fewer than K tumors have mutations, K = 3

Survival analysis

For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References

[1] Bland and Altman, Statistics notes: The logrank test, BMJ 328(7447):1073 (2004)

[2] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[3] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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