Correlation between gene mutation status and molecular subtypes
Overview
Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 197 genes and 12 molecular subtypes across 248 patients, 417 significant findings detected with P value < 0.05 and Q value < 0.25.

  • PTEN mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'METHLYATION_CNMF',  'RPPA_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • PIK3R1 mutation correlated to 'CN_CNMF',  'METHLYATION_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.

  • TP53 mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'METHLYATION_CNMF',  'RPPA_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • CTCF mutation correlated to 'CN_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • FBXW7 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • PIK3CA mutation correlated to 'RPPA_CNMF'.

  • ARID1A mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.

  • ARHGAP35 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.

  • KRAS mutation correlated to 'MRNA_CHIERARCHICAL',  'CN_CNMF',  'RPPA_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • CTNNB1 mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'METHLYATION_CNMF',  'RPPA_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • ZFHX3 mutation correlated to 'CN_CNMF',  'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • TCP11L2 mutation correlated to 'MRNA_CHIERARCHICAL',  'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • VPS11 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • PPP2R1A mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • SOX17 mutation correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.

  • CCND1 mutation correlated to 'CN_CNMF'.

  • EP300 mutation correlated to 'CN_CNMF',  'RPPA_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • KLHL8 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • ALG8 mutation correlated to 'RPPA_CNMF'.

  • GNPTAB mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • SIN3A mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.

  • ARID5B mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • NFE2L2 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • ZNF471 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.

  • MORC4 mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.

  • SELP mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • RBMX mutation correlated to 'CN_CNMF'.

  • FAT1 mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'METHLYATION_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • MARK3 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.

  • SOS1 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • RBBP6 mutation correlated to 'MRNA_CHIERARCHICAL',  'CN_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • ZNF263 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • INTS7 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • L1TD1 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • NAT1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • JAKMIP2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ING1 mutation correlated to 'CN_CNMF'.

  • CCDC6 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.

  • ZNF781 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • MKI67 mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • EIF2S2 mutation correlated to 'CN_CNMF'.

  • BCOR mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • RASA1 mutation correlated to 'CN_CNMF'.

  • DNER mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • CUX1 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • CDK17 mutation correlated to 'MRNA_CHIERARCHICAL',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • USP28 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • MSH6 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • C14ORF166B mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ATM mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • RAE1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ZNF485 mutation correlated to 'CN_CNMF'.

  • POLE mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • AHCYL1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ZNF334 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • SACS mutation correlated to 'MRNA_CHIERARCHICAL',  'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • MSH4 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • SLC26A8 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • KIF20B mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • CTNND1 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • NFE2L3 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • FAM65B mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • RNF43 mutation correlated to 'MRNA_CHIERARCHICAL',  'CN_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • MRPL47 mutation correlated to 'MRNASEQ_CNMF'.

  • TIGD4 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • FILIP1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • SLC1A3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • UFSP2 mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • WBP4 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • TRIM59 mutation correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • RSBN1L mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • LNX2 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.

  • ALPK2 mutation correlated to 'MRNA_CHIERARCHICAL',  'CN_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • REV3L mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • CAB39L mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.

  • ERBB3 mutation correlated to 'RPPA_CHIERARCHICAL'.

  • INPP4B mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • C1ORF100 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • IL20 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.

  • TAP1 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • RHBDD3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • BRDT mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • RB1 mutation correlated to 'MRNA_CHIERARCHICAL' and 'MRNASEQ_CHIERARCHICAL'.

  • MFAP5 mutation correlated to 'CN_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • NAA15 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ZRANB3 mutation correlated to 'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • SLC34A3 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • MLH3 mutation correlated to 'CN_CNMF'.

  • CCDC147 mutation correlated to 'CN_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • ZNF662 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • PSMC4 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • CCDC160 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • PPIL4 mutation correlated to 'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • CCDC144A mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • TUBGCP6 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • TTC39C mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • COL8A1 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.

  • PER3 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • MGA mutation correlated to 'RPPA_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.

  • GPRASP1 mutation correlated to 'CN_CNMF'.

  • PPM1D mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • ZNF674 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ZNF606 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • TXNRD1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • LETMD1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ZNF721 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • AGXT2 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • ATP6V1C2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • DYM mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • TAB3 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • ZNF649 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • FN1 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • CCDC150 mutation correlated to 'CN_CNMF'.

  • KIF21A mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • BHLHB9 mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CNMF'.

  • EXOSC9 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • ZKSCAN1 mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • OR8B8 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • SENP7 mutation correlated to 'MRNA_CHIERARCHICAL',  'CN_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • NRIP1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • MCTP1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • CCDC146 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • ZNF620 mutation correlated to 'RPPA_CNMF'.

  • PTPN12 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • RIOK3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • CASP8 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • GFAP mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • DENND3 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • CHEK2 mutation correlated to 'CN_CNMF',  'RPPA_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • ZMYM2 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • DEPDC1B mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.

  • C3AR1 mutation correlated to 'CN_CNMF'.

  • STK3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • FOXJ3 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • ZNF385B mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ATF6 mutation correlated to 'CN_CNMF'.

  • LIMA1 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • PPIG mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • ZNF774 mutation correlated to 'CN_CNMF'.

  • PARG mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • PSMD3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • STRN3 mutation correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • MLL4 mutation correlated to 'CN_CNMF',  'METHLYATION_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.

  • MSN mutation correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.

  • MAPK8 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • RBL2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • PDGFRA mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • RG9MTD3 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • KANK4 mutation correlated to 'CN_CNMF'.

  • MYOM1 mutation correlated to 'MIRSEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • MORC3 mutation correlated to 'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.

  • CCDC82 mutation correlated to 'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • NOC3L mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • ASXL2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • NIPA2 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • C14ORF118 mutation correlated to 'CN_CNMF'.

  • THAP5 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • ZNF611 mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • ZCCHC18 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • PRKCE mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • BMP2K mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • PRPF38B mutation correlated to 'CN_CNMF',  'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.

  • LGMN mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • SSH2 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.

  • EMR1 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • OR5AK2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • C1ORF101 mutation correlated to 'CN_CNMF'.

  • ZNF534 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • FAM122A mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between mutation status of 197 genes and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 417 significant findings detected.

Clinical
Features 		MRNA
CNMF 		MRNA
CHIERARCHICAL 		CN
CNMF 		METHLYATION
CNMF 		RPPA
CNMF 		RPPA
CHIERARCHICAL 		MRNASEQ
CNMF 		MRNASEQ
CHIERARCHICAL 		MIRSEQ
CNMF 		MIRSEQ
CHIERARCHICAL 		MIRSEQ
MATURE
CNMF 		MIRSEQ
MATURE
CHIERARCHICAL
nMutated (%) nWild-Type Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test
PTEN 161 (65%) 87 0.0016
(0.0308) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		0.00111
(0.0236) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		3e-05
(0.00187) 		1e-05
(0.000844)
TP53 69 (28%) 179 4e-05
(0.00231) 		2e-05
(0.00148) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844)
CTNNB1 74 (30%) 174 8e-05
(0.00394) 		2e-05
(0.00148) 		3e-05
(0.00187) 		0.00069
(0.0181) 		3e-05
(0.00187) 		0.21
(0.537) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		1e-05
(0.000844) 		0.00707
(0.0777) 		0.00122
(0.0255)
CTCF 44 (18%) 204 0.0723
(0.325) 		0.202
(0.53) 		4e-05
(0.00231) 		0.134
(0.443) 		0.587
(0.889) 		0.0234
(0.172) 		0.00066
(0.0175) 		0.00105
(0.0236) 		0.00046
(0.0141) 		0.0184
(0.146) 		0.0269
(0.19) 		0.0101
(0.101)
RNF43 12 (5%) 236 0.19
(0.519) 		0.00937
(0.0955) 		0.044
(0.25) 		0.708
(0.983) 		0.565
(0.87) 		0.495
(0.829) 		0.0337
(0.219) 		0.0001
(0.00446) 		0.0392
(0.233) 		0.0209
(0.158) 		0.072
(0.324) 		0.022
(0.164)
PIK3R1 82 (33%) 166 0.0735
(0.326) 		0.0607
(0.295) 		0.0085
(0.0888) 		0.0002
(0.0075) 		0.831
(1.00) 		0.115
(0.403) 		5e-05
(0.00269) 		0.0002
(0.0075) 		0.0124
(0.117) 		0.00055
(0.0158) 		0.609
(0.91) 		0.093
(0.356)
KRAS 52 (21%) 196 0.186
(0.517) 		0.0362
(0.228) 		0.00125
(0.0259) 		0.274
(0.632) 		0.00539
(0.0649) 		0.371
(0.713) 		0.00185
(0.0334) 		0.00023
(0.00824) 		1e-05
(0.000844) 		0.125
(0.422) 		0.35
(0.691) 		0.223
(0.56)
ATM 29 (12%) 219 0.0282
(0.196) 		0.00023
(0.00824) 		0.00308
(0.0455) 		1
(1.00) 		0.611
(0.91) 		0.535
(0.853) 		0.195
(0.525) 		0.00036
(0.0115) 		0.0281
(0.196) 		0.967
(1.00) 		0.89
(1.00) 		0.041
(0.24)
CCDC147 15 (6%) 233 0.813
(1.00) 		0.0909
(0.356) 		0.00089
(0.0215) 		0.409
(0.751) 		0.124
(0.418) 		0.013
(0.122) 		0.00158
(0.0308) 		0.00013
(0.00549) 		0.00051
(0.0153) 		0.224
(0.561) 		0.359
(0.701) 		0.0427
(0.246)
FBXW7 38 (15%) 210 0.701
(0.982) 		0.268
(0.622) 		0.0776
(0.333) 		0.174
(0.499) 		0.382
(0.726) 		0.474
(0.81) 		0.0169
(0.141) 		0.003
(0.0452) 		0.0157
(0.135) 		0.0757
(0.333) 		0.00847
(0.0888) 		0.0373
(0.228)
ARID1A 83 (33%) 165 0.278
(0.633) 		0.073
(0.326) 		1e-05
(0.000844) 		0.608
(0.91) 		0.456
(0.789) 		0.308
(0.651) 		0.00239
(0.0386) 		1e-05
(0.000844) 		5e-05
(0.00269) 		0.00022
(0.00813) 		0.16
(0.474) 		0.148
(0.464)
PPP2R1A 28 (11%) 220 0.119
(0.409) 		0.0554
(0.282) 		0.122
(0.413) 		0.111
(0.393) 		0.132
(0.436) 		0.0645
(0.307) 		0.00713
(0.078) 		0.0233
(0.172) 		0.0731
(0.326) 		0.00472
(0.0613) 		0.0024
(0.0386) 		0.0228
(0.169)
FAT1 40 (16%) 208 0.0122
(0.117) 		0.00144
(0.0291) 		0.113
(0.396) 		0.0322
(0.213) 		0.664
(0.952) 		0.0704
(0.322) 		0.0654
(0.309) 		8e-05
(0.00394) 		0.0148
(0.131) 		0.0709
(0.323) 		0.852
(1.00) 		0.217
(0.548)
MKI67 29 (12%) 219 0.00339
(0.0486) 		0.0162
(0.137) 		1e-05
(0.000844) 		0.732
(0.994) 		0.984
(1.00) 		0.674
(0.961) 		0.201
(0.53) 		0.00031
(0.0103) 		0.0148
(0.131) 		0.291
(0.639) 		0.655
(0.95) 		0.318
(0.656)
MFAP5 9 (4%) 239 0.0369
(0.228) 		0.432
(0.77) 		0.16
(0.475) 		0.0169
(0.141) 		0.00239
(0.0386) 		0.00283
(0.0432) 		0.00492
(0.0619) 		0.183
(0.51) 		0.21
(0.537) 		0.142
(0.458)
MGA 26 (10%) 222 0.33
(0.67) 		0.364
(0.703) 		0.191
(0.519) 		1
(1.00) 		0.0366
(0.228) 		0.164
(0.481) 		0.00388
(0.0533) 		0.00212
(0.0369) 		0.0424
(0.246) 		0.161
(0.475) 		0.0346
(0.223) 		0.0935
(0.356)
SENP7 12 (5%) 236 0.356
(0.701) 		0.0352
(0.224) 		0.0179
(0.144) 		0.71
(0.983) 		0.763
(1.00) 		0.665
(0.952) 		0.035
(0.224) 		5e-05
(0.00269) 		0.02
(0.152) 		0.0453
(0.254)
MLL4 30 (12%) 218 0.811
(1.00) 		0.0926
(0.356) 		3e-05
(0.00187) 		0.0286
(0.197) 		0.266
(0.619) 		0.15
(0.465) 		0.0131
(0.122) 		0.00056
(0.0158) 		0.00598
(0.0696) 		0.504
(0.829) 		0.231
(0.576) 		0.931
(1.00)
ARHGAP35 36 (15%) 212 0.519
(0.841) 		0.889
(1.00) 		0.227
(0.567) 		0.857
(1.00) 		0.233
(0.578) 		0.291
(0.639) 		0.0316
(0.211) 		0.00701
(0.0775) 		0.00235
(0.0386) 		0.455
(0.789) 		0.0431
(0.247) 		0.09
(0.356)
TCP11L2 14 (6%) 234 0.104
(0.377) 		0.0184
(0.146) 		0.00391
(0.0534) 		0.298
(0.643) 		0.712
(0.983) 		0.648
(0.945) 		0.175
(0.499) 		7e-05
(0.00368) 		0.00173
(0.032) 		0.498
(0.829) 		0.662
(0.952) 		0.192
(0.519)
SIN3A 21 (8%) 227 0.0122
(0.117) 		0.357
(0.701) 		0.0693
(0.318) 		0.0778
(0.333) 		0.00223
(0.0376) 		0.00024
(0.00834) 		0.0467
(0.259) 		0.00524
(0.0642) 		0.19
(0.519) 		0.287
(0.634)
SACS 26 (10%) 222 0.049
(0.262) 		0.00147
(0.0294) 		0.00129
(0.0265) 		0.542
(0.858) 		0.762
(1.00) 		0.774
(1.00) 		0.0449
(0.253) 		0.00168
(0.0317) 		0.0079
(0.0845) 		0.155
(0.47) 		0.682
(0.965) 		0.631
(0.93)
KIF20B 21 (8%) 227 0.442
(0.78) 		0.045
(0.253) 		0.00061
(0.017) 		0.733
(0.994) 		0.793
(1.00) 		0.422
(0.76) 		0.0132
(0.122) 		0.0002
(0.0075) 		0.00226
(0.0376) 		0.268
(0.622) 		0.738
(0.997) 		0.318
(0.656)
UFSP2 11 (4%) 237 0.554
(0.865) 		0.248
(0.601) 		0.0324
(0.213) 		0.413
(0.754) 		0.915
(1.00) 		0.664
(0.952) 		0.0172
(0.143) 		9e-05
(0.00417) 		0.0332
(0.217) 		0.204
(0.53) 		0.425
(0.763) 		0.0904
(0.356)
ZRANB3 7 (3%) 241 0.157
(0.473) 		0.407
(0.751) 		0.00853
(0.0888) 		0.0372
(0.228) 		0.00505
(0.0632) 		0.0322
(0.213) 		0.134
(0.443)
ZNF662 13 (5%) 235 0.504
(0.829) 		0.283
(0.633) 		0.161
(0.476) 		0.407
(0.751) 		0.346
(0.688) 		0.129
(0.43) 		0.012
(0.116) 		4e-05
(0.00231) 		0.0181
(0.145) 		0.149
(0.464) 		0.361
(0.702) 		0.0423
(0.246)
COL8A1 10 (4%) 238 0.0558
(0.283) 		0.138
(0.45) 		0.0906
(0.356) 		0.71
(0.983) 		0.389
(0.734) 		0.311
(0.652) 		0.00095
(0.0225) 		0.0136
(0.124) 		0.00577
(0.0681) 		0.0173
(0.143) 		0.153
(0.468) 		0.0931
(0.356)
DYM 10 (4%) 238 0.0174
(0.143) 		0.485
(0.819) 		0.308
(0.65) 		0.158
(0.473) 		0.00138
(0.0281) 		0.00336
(0.0484) 		0.0251
(0.182) 		0.314
(0.655) 		0.254
(0.606) 		0.0658
(0.309)
ZKSCAN1 7 (3%) 241 0.00581
(0.0681) 		0.708
(0.983) 		0.837
(1.00) 		0.166
(0.483) 		0.0151
(0.133) 		0.0244
(0.177) 		0.0286
(0.197) 		0.338
(0.68) 		0.255
(0.606) 		0.56
(0.865)
MORC3 10 (4%) 238 0.192
(0.519) 		0.411
(0.752) 		0.0641
(0.306) 		0.0565
(0.285) 		3e-05
(0.00187) 		0.00024
(0.00834) 		0.0508
(0.269) 		0.0365
(0.228) 		0.0169
(0.141) 		0.0656
(0.309)
ZNF611 12 (5%) 236 1
(1.00) 		0.0787
(0.333) 		0.0114
(0.112) 		0.407
(0.751) 		0.116
(0.405) 		0.0999
(0.369) 		0.0898
(0.356) 		0.00304
(0.0455) 		0.0384
(0.23) 		0.145
(0.46) 		0.362
(0.702) 		0.0301
(0.205)
ZFHX3 44 (18%) 204 0.171
(0.492) 		0.181
(0.507) 		0.00487
(0.0618) 		0.0159
(0.135) 		0.283
(0.633) 		0.803
(1.00) 		0.747
(1.00) 		0.00688
(0.0769) 		0.139
(0.453) 		0.179
(0.507) 		0.578
(0.882) 		0.447
(0.782)
VPS11 11 (4%) 237 0.507
(0.829) 		0.282
(0.633) 		0.404
(0.748) 		0.815
(1.00) 		0.773
(1.00) 		0.388
(0.734) 		0.0157
(0.135) 		0.0132
(0.122) 		0.0121
(0.116) 		0.538
(0.853)
EP300 21 (8%) 227 1
(1.00) 		0.914
(1.00) 		0.00175
(0.0321) 		0.395
(0.742) 		0.0351
(0.224) 		0.117
(0.405) 		0.346
(0.688) 		0.032
(0.213) 		0.0942
(0.356) 		0.311
(0.652) 		1
(1.00) 		0.157
(0.473)
ZNF471 15 (6%) 233 0.815
(1.00) 		0.0927
(0.356) 		0.00455
(0.0601) 		0.536
(0.853) 		0.638
(0.936) 		0.449
(0.785) 		0.494
(0.829) 		8e-05
(0.00394) 		0.0475
(0.261) 		0.0259
(0.185) 		1
(1.00) 		0.852
(1.00)
MORC4 20 (8%) 228 0.359
(0.701) 		0.887
(1.00) 		0.00656
(0.0749) 		0.324
(0.661) 		0.303
(0.647) 		0.0576
(0.287) 		0.00702
(0.0775) 		0.0827
(0.34) 		0.244
(0.595) 		0.0312
(0.209) 		0.484
(0.818) 		0.189
(0.519)
SELP 10 (4%) 238 0.506
(0.829) 		0.283
(0.633) 		0.159
(0.473) 		0.787
(1.00) 		0.838
(1.00) 		0.523
(0.843) 		0.0176
(0.144) 		0.00664
(0.0753) 		0.025
(0.181) 		0.313
(0.655)
RBBP6 22 (9%) 226 0.79
(1.00) 		0.02
(0.152) 		0.00018
(0.00709) 		0.92
(1.00) 		0.741
(0.998) 		0.727
(0.992) 		0.109
(0.389) 		0.00011
(0.00482) 		0.095
(0.359) 		0.102
(0.373) 		0.484
(0.818) 		0.348
(0.689)
BCOR 30 (12%) 218 0.855
(1.00) 		0.204
(0.53) 		0.00169
(0.0317) 		0.102
(0.373) 		0.999
(1.00) 		0.317
(0.656) 		0.0011
(0.0236) 		0.00459
(0.0603) 		0.15
(0.465) 		0.0483
(0.261) 		0.321
(0.659) 		0.784
(1.00)
CUX1 21 (8%) 227 1
(1.00) 		0.654
(0.95) 		9e-05
(0.00417) 		0.509
(0.83) 		0.919
(1.00) 		0.786
(1.00) 		0.324
(0.661) 		0.00262
(0.041) 		0.0307
(0.208) 		0.358
(0.701) 		0.192
(0.519) 		0.612
(0.91)
CDK17 14 (6%) 234 0.1
(0.37) 		0.0019
(0.0338) 		0.149
(0.465) 		0.119
(0.409) 		0.559
(0.865) 		0.968
(1.00) 		0.88
(1.00) 		0.0298
(0.204) 		0.18
(0.507) 		0.939
(1.00) 		0.454
(0.788) 		0.0135
(0.124)
USP28 10 (4%) 238 0.0189
(0.149) 		0.711
(0.983) 		0.782
(1.00) 		0.473
(0.809) 		0.302
(0.647) 		0.00926
(0.0948) 		0.16
(0.475) 		0.601
(0.905) 		1
(1.00) 		0.0367
(0.228)
LNX2 14 (6%) 234 0.504
(0.829) 		0.284
(0.633) 		0.0311
(0.209) 		0.166
(0.483) 		0.909
(1.00) 		0.378
(0.719) 		0.049
(0.262) 		0.00281
(0.0431) 		0.048
(0.261) 		0.00462
(0.0603) 		0.627
(0.924) 		0.792
(1.00)
ALPK2 19 (8%) 229 0.0483
(0.261) 		0.0146
(0.13) 		0.00109
(0.0236) 		0.903
(1.00) 		0.832
(1.00) 		0.358
(0.701) 		0.125
(0.422) 		0.00335
(0.0484) 		0.0463
(0.258) 		0.716
(0.985) 		0.909
(1.00) 		0.145
(0.46)
REV3L 20 (8%) 228 0.506
(0.829) 		0.283
(0.633) 		0.0007
(0.0182) 		0.646
(0.943) 		0.522
(0.843) 		0.654
(0.95) 		0.0383
(0.23) 		0.00106
(0.0236) 		0.219
(0.552) 		0.0957
(0.36) 		0.657
(0.95) 		0.157
(0.473)
SLC34A3 6 (2%) 242 0.209
(0.537) 		0.708
(0.983) 		0.129
(0.43) 		0.403
(0.747) 		0.0393
(0.233) 		0.0406
(0.239) 		0.472
(0.809) 		0.577
(0.881) 		0.359
(0.701) 		0.0432
(0.248)
PPIL4 11 (4%) 237 0.506
(0.829) 		0.283
(0.633) 		0.0963
(0.361) 		1
(1.00) 		0.896
(1.00) 		0.18
(0.507) 		0.259
(0.61) 		0.00233
(0.0385) 		0.0437
(0.249) 		0.104
(0.377) 		0.401
(0.747) 		0.00557
(0.0662)
ZNF606 16 (6%) 232 0.191
(0.519) 		0.0921
(0.356) 		0.00541
(0.0649) 		0.289
(0.636) 		0.887
(1.00) 		0.72
(0.988) 		0.234
(0.578) 		0.00255
(0.0402) 		0.00444
(0.059) 		0.657
(0.95) 		0.456
(0.79) 		0.303
(0.647)
TAB3 18 (7%) 230 0.189
(0.519) 		0.0913
(0.356) 		9e-05
(0.00417) 		0.51
(0.83) 		0.957
(1.00) 		0.736
(0.994) 		0.191
(0.519) 		3e-05
(0.00187) 		0.00185
(0.0334) 		0.306
(0.648) 		0.301
(0.647) 		1
(1.00)
FN1 24 (10%) 224 0.209
(0.537) 		0.0591
(0.292) 		0.00582
(0.0681) 		0.626
(0.924) 		0.909
(1.00) 		0.523
(0.843) 		0.0641
(0.306) 		1e-05
(0.000844) 		0.01
(0.101) 		0.252
(0.604) 		0.624
(0.922) 		0.313
(0.655)
CASP8 17 (7%) 231 0.504
(0.829) 		0.077
(0.333) 		0.0068
(0.0765) 		0.543
(0.858) 		0.254
(0.606) 		0.681
(0.964) 		0.369
(0.71) 		0.00421
(0.0565) 		0.0178
(0.144) 		0.603
(0.906) 		0.259
(0.61) 		0.269
(0.622)
DENND3 15 (6%) 233 0.506
(0.829) 		0.282
(0.633) 		0.00166
(0.0316) 		0.472
(0.809) 		0.323
(0.661) 		0.233
(0.578) 		0.121
(0.413) 		2e-05
(0.00148) 		0.00486
(0.0618) 		0.4
(0.747) 		0.115
(0.403) 		0.561
(0.865)
CHEK2 12 (5%) 236 0.855
(1.00) 		0.205
(0.53) 		0.0408
(0.24) 		0.859
(1.00) 		0.0122
(0.117) 		0.143
(0.459) 		0.727
(0.992) 		0.00064
(0.0175) 		0.936
(1.00) 		0.351
(0.693) 		1
(1.00) 		1
(1.00)
ZMYM2 17 (7%) 231 0.506
(0.829) 		0.0774
(0.333) 		0.00636
(0.073) 		0.741
(0.998) 		0.439
(0.776) 		0.255
(0.606) 		0.363
(0.702) 		0.019
(0.149) 		0.18
(0.507) 		0.796
(1.00) 		0.364
(0.702) 		0.0193
(0.15)
DEPDC1B 11 (4%) 237 0.854
(1.00) 		0.208
(0.535) 		0.00018
(0.00709) 		0.762
(1.00) 		0.689
(0.972) 		0.361
(0.702) 		0.0379
(0.229) 		0.1
(0.37) 		0.164
(0.48) 		0.372
(0.714) 		0.0378
(0.229) 		0.302
(0.647)
FOXJ3 10 (4%) 238 0.506
(0.829) 		0.282
(0.633) 		0.0641
(0.306) 		1
(1.00) 		0.46
(0.793) 		0.921
(1.00) 		0.044
(0.25) 		0.00444
(0.059) 		0.0622
(0.301) 		0.203
(0.53) 		0.104
(0.377) 		0.0358
(0.228)
LIMA1 8 (3%) 240 0.414
(0.755) 		0.676
(0.961) 		0.284
(0.633) 		0.523
(0.843) 		0.0022
(0.0374) 		0.00272
(0.0423) 		0.0321
(0.213) 		0.0704
(0.322)
CCDC82 12 (5%) 236 0.507
(0.829) 		0.281
(0.633) 		0.157
(0.473) 		1
(1.00) 		0.671
(0.958) 		0.18
(0.507) 		0.0542
(0.28) 		0.00314
(0.0461) 		0.0418
(0.244) 		0.182
(0.51) 		0.403
(0.747) 		0.0198
(0.152)
BMP2K 13 (5%) 235 0.192
(0.519) 		0.0913
(0.356) 		0.00516
(0.0635) 		0.533
(0.853) 		0.699
(0.98) 		0.911
(1.00) 		0.0306
(0.208) 		0.0158
(0.135) 		0.726
(0.992) 		0.464
(0.799) 		0.939
(1.00) 		1
(1.00)
PRPF38B 11 (4%) 237 0.00666
(0.0753) 		0.299
(0.644) 		0.851
(1.00) 		1
(1.00) 		0.19
(0.519) 		0.00043
(0.0134) 		0.711
(0.983) 		0.0234
(0.172) 		0.858
(1.00) 		0.142
(0.458)
FAM122A 6 (2%) 242 0.0158
(0.135) 		0.194
(0.524) 		0.175
(0.499) 		0.0103
(0.103) 		0.00515
(0.0635) 		0.0775
(0.333) 		0.243
(0.594)
SOX17 7 (3%) 241 0.0003
(0.0101) 		0.0381
(0.229) 		0.353
(0.695) 		1
(1.00) 		0.401
(0.747) 		0.486
(0.819) 		0.0914
(0.356) 		0.548
(0.862)
KLHL8 12 (5%) 236 0.506
(0.829) 		0.282
(0.633) 		0.0275
(0.192) 		0.299
(0.645) 		0.99
(1.00) 		0.964
(1.00) 		0.151
(0.466) 		0.00482
(0.0618) 		0.12
(0.41) 		0.693
(0.974) 		0.53
(0.85) 		0.364
(0.702)
GNPTAB 20 (8%) 228 0.458
(0.79) 		0.0778
(0.333) 		0.00972
(0.0986) 		0.387
(0.733) 		0.296
(0.642) 		0.633
(0.93) 		0.173
(0.496) 		0.00043
(0.0134) 		0.156
(0.471) 		0.0765
(0.333) 		0.0698
(0.32) 		0.288
(0.634)
ARID5B 29 (12%) 219 0.925
(1.00) 		0.138
(0.45) 		0.00362
(0.0509) 		0.215
(0.543) 		0.487
(0.821) 		0.842
(1.00) 		0.0969
(0.363) 		0.0428
(0.246) 		0.0627
(0.302) 		0.315
(0.655) 		0.609
(0.91) 		0.864
(1.00)
NFE2L2 14 (6%) 234 0.19
(0.519) 		0.323
(0.661) 		0.839
(1.00) 		0.861
(1.00) 		0.259
(0.61) 		0.0554
(0.282) 		0.0115
(0.112) 		0.019
(0.149) 		0.108
(0.387) 		0.0693
(0.318) 		0.13
(0.431) 		0.506
(0.829)
MARK3 11 (4%) 237 0.19
(0.519) 		0.0936
(0.356) 		0.0615
(0.299) 		0.139
(0.451) 		0.0925
(0.356) 		0.304
(0.647) 		0.0525
(0.273) 		0.00051
(0.0153) 		0.178
(0.506) 		0.0107
(0.106)
SOS1 12 (5%) 236 0.812
(1.00) 		0.81
(1.00) 		0.0272
(0.192) 		0.818
(1.00) 		0.582
(0.886) 		0.17
(0.492) 		0.402
(0.747) 		0.0389
(0.232) 		0.416
(0.756) 		0.669
(0.956) 		0.592
(0.894) 		0.0916
(0.356)
ZNF263 7 (3%) 241 0.0257
(0.184) 		0.818
(1.00) 		0.0494
(0.263) 		0.708
(0.983) 		0.654
(0.95) 		0.034
(0.22) 		0.232
(0.577) 		0.386
(0.732) 		0.473
(0.809) 		0.065
(0.308)
L1TD1 16 (6%) 232 0.00109
(0.0236) 		0.0717
(0.324) 		0.202
(0.53) 		0.37
(0.71) 		0.267
(0.619) 		0.00109
(0.0236) 		0.262
(0.614) 		0.204
(0.53) 		0.775
(1.00) 		0.6
(0.905)
ZNF781 10 (4%) 238 0.00308
(0.0455) 		0.573
(0.879) 		0.181
(0.507) 		0.688
(0.97) 		0.194
(0.523) 		0.0136
(0.124) 		0.277
(0.633) 		0.834
(1.00) 		0.922
(1.00) 		0.433
(0.77)
POLE 27 (11%) 221 0.772
(1.00) 		0.0606
(0.295) 		0.0001
(0.00446) 		0.285
(0.634) 		0.616
(0.915) 		0.728
(0.992) 		0.271
(0.626) 		0.0124
(0.117) 		0.103
(0.375) 		0.333
(0.674) 		0.656
(0.95) 		0.512
(0.833)
ZNF334 17 (7%) 231 1
(1.00) 		0.0787
(0.333) 		0.0069
(0.0769) 		0.716
(0.985) 		0.653
(0.95) 		0.647
(0.944) 		0.144
(0.459) 		0.013
(0.122) 		0.357
(0.701) 		0.605
(0.908) 		0.526
(0.846) 		0.359
(0.701)
MSH4 15 (6%) 233 0.812
(1.00) 		0.0916
(0.356) 		0.00405
(0.055) 		1
(1.00) 		0.916
(1.00) 		0.952
(1.00) 		0.43
(0.77) 		0.0282
(0.196) 		0.433
(0.77) 		0.311
(0.652) 		1
(1.00) 		0.559
(0.865)
SLC26A8 12 (5%) 236 0.00326
(0.0476) 		1
(1.00) 		0.288
(0.634) 		0.436
(0.773) 		0.685
(0.967) 		0.00065
(0.0175) 		0.196
(0.527) 		0.28
(0.633) 		0.924
(1.00) 		0.302
(0.647)
CTNND1 19 (8%) 229 0.445
(0.782) 		0.4
(0.747) 		0.0194
(0.151) 		0.292
(0.64) 		0.626
(0.924) 		0.175
(0.499) 		0.757
(1.00) 		0.0401
(0.237) 		0.403
(0.747) 		0.906
(1.00) 		0.296
(0.642) 		0.362
(0.702)
NFE2L3 12 (5%) 236 0.648
(0.946) 		0.0812
(0.336) 		0.711
(0.983) 		0.295
(0.642) 		0.0735
(0.326) 		0.0196
(0.151) 		0.249
(0.601) 		0.244
(0.595) 		0.695
(0.976) 		0.0389
(0.232)
FAM65B 16 (6%) 232 0.0145
(0.13) 		0.703
(0.983) 		0.558
(0.865) 		0.449
(0.785) 		0.232
(0.577) 		0.0072
(0.0781) 		0.256
(0.607) 		0.786
(1.00) 		0.296
(0.642) 		0.32
(0.659)
TIGD4 13 (5%) 235 1
(1.00) 		0.583
(0.887) 		0.0195
(0.151) 		1
(1.00) 		0.199
(0.527) 		0.08
(0.334) 		0.223
(0.56) 		0.00148
(0.0294) 		0.198
(0.527) 		0.277
(0.633) 		0.924
(1.00) 		0.433
(0.77)
CAB39L 8 (3%) 240 0.097
(0.363) 		0.502
(0.829) 		0.145
(0.459) 		0.283
(0.633) 		0.0182
(0.145) 		0.277
(0.633) 		0.0212
(0.159)
INPP4B 12 (5%) 236 0.46
(0.793) 		0.0783
(0.333) 		0.00173
(0.032) 		0.34
(0.682) 		0.389
(0.734) 		0.873
(1.00) 		0.00246
(0.0393) 		0.386
(0.733) 		0.668
(0.956)
IL20 7 (3%) 241 0.19
(0.519) 		0.0913
(0.356) 		0.254
(0.606) 		0.946
(1.00) 		0.538
(0.853) 		0.197
(0.527) 		0.0182
(0.145) 		0.153
(0.468) 		0.0199
(0.152)
TAP1 8 (3%) 240 0.144
(0.459) 		1
(1.00) 		0.929
(1.00) 		0.675
(0.961) 		0.0112
(0.11) 		0.003
(0.0452) 		0.132
(0.437) 		0.0473
(0.261)
BRDT 14 (6%) 234 1
(1.00) 		0.913
(1.00) 		0.00617
(0.0713) 		1
(1.00) 		0.466
(0.802) 		0.236
(0.582) 		0.165
(0.483) 		0.00777
(0.0835) 		0.334
(0.674) 		0.18
(0.507) 		0.663
(0.952) 		0.343
(0.684)
RB1 20 (8%) 228 0.774
(1.00) 		0.0054
(0.0649) 		0.0891
(0.356) 		0.543
(0.858) 		0.582
(0.886) 		0.512
(0.833) 		0.611
(0.91) 		0.00013
(0.00549) 		0.835
(1.00) 		0.484
(0.818) 		1
(1.00) 		0.0671
(0.313)
PSMC4 11 (4%) 237 0.00375
(0.0521) 		0.71
(0.983) 		0.239
(0.586) 		0.522
(0.843) 		0.975
(1.00) 		0.00868
(0.0896) 		0.0991
(0.369) 		1
(1.00) 		0.0715
(0.324) 		0.558
(0.865)
CCDC160 11 (4%) 237 0.855
(1.00) 		0.203
(0.53) 		0.0173
(0.143) 		1
(1.00) 		0.789
(1.00) 		0.603
(0.906) 		0.818
(1.00) 		0.026
(0.185) 		0.286
(0.634) 		0.601
(0.905) 		0.726
(0.992) 		0.796
(1.00)
CCDC144A 18 (7%) 230 0.923
(1.00) 		0.0912
(0.356) 		0.0367
(0.228) 		0.904
(1.00) 		0.238
(0.585) 		0.332
(0.672) 		0.349
(0.69) 		0.00386
(0.0533) 		0.22
(0.553) 		0.197
(0.527) 		0.771
(1.00) 		0.414
(0.755)
TUBGCP6 20 (8%) 228 0.0154
(0.134) 		0.184
(0.511) 		0.389
(0.734) 		0.294
(0.642) 		0.625
(0.924) 		0.00086
(0.021) 		0.0648
(0.308) 		0.546
(0.861) 		0.963
(1.00) 		0.91
(1.00)
PER3 12 (5%) 236 0.0145
(0.13) 		0.361
(0.702) 		0.198
(0.527) 		0.21
(0.537) 		0.147
(0.462) 		0.00072
(0.0183) 		0.0877
(0.355) 		0.0458
(0.256) 		0.0715
(0.324) 		0.0924
(0.356)
PPM1D 11 (4%) 237 0.505
(0.829) 		0.282
(0.633) 		0.0255
(0.183) 		0.227
(0.567) 		0.409
(0.751) 		0.748
(1.00) 		0.0522
(0.273) 		0.0422
(0.246) 		0.811
(1.00) 		0.339
(0.68) 		0.663
(0.952) 		0.56
(0.865)
ZNF721 13 (5%) 235 1
(1.00) 		0.0797
(0.334) 		0.00113
(0.0239) 		1
(1.00) 		0.0787
(0.333) 		0.202
(0.53) 		0.41
(0.751) 		0.00544
(0.0649) 		0.199
(0.527) 		0.277
(0.633) 		1
(1.00) 		1
(1.00)
AGXT2 11 (4%) 237 0.375
(0.717) 		0.809
(1.00) 		0.0326
(0.213) 		0.851
(1.00) 		0.503
(0.829) 		0.653
(0.95) 		0.19
(0.519) 		0.00737
(0.0796) 		0.275
(0.633) 		0.104
(0.377) 		0.858
(1.00) 		0.212
(0.539)
ZNF649 14 (6%) 234 0.553
(0.865) 		0.249
(0.601) 		0.00071
(0.0182) 		0.78
(1.00) 		0.98
(1.00) 		0.955
(1.00) 		0.454
(0.788) 		0.014
(0.127) 		0.152
(0.468) 		0.817
(1.00) 		0.925
(1.00) 		0.303
(0.647)
KIF21A 15 (6%) 233 0.853
(1.00) 		0.203
(0.53) 		0.0022
(0.0374) 		0.288
(0.634) 		0.0674
(0.314) 		0.581
(0.886) 		0.306
(0.648) 		0.00091
(0.0217) 		0.742
(0.999) 		0.254
(0.606) 		0.812
(1.00) 		0.56
(0.865)
BHLHB9 8 (3%) 240 0.0804
(0.335) 		1
(1.00) 		0.759
(1.00) 		0.248
(0.601) 		0.128
(0.43) 		0.0362
(0.228) 		0.00355
(0.0504) 		0.071
(0.323)
EXOSC9 10 (4%) 238 0.856
(1.00) 		0.204
(0.53) 		0.0312
(0.209) 		0.31
(0.652) 		0.853
(1.00) 		0.746
(1.00) 		0.302
(0.647) 		0.0016
(0.0308) 		0.342
(0.684) 		0.764
(1.00)
CCDC146 14 (6%) 234 1
(1.00) 		0.0479
(0.261) 		0.00149
(0.0294) 		1
(1.00) 		0.259
(0.61) 		0.362
(0.702) 		0.358
(0.701) 		0.00099
(0.0229) 		0.102
(0.373) 		0.18
(0.507) 		0.923
(1.00) 		0.431
(0.77)
PTPN12 10 (4%) 238 0.111
(0.392) 		0.152
(0.468) 		0.0786
(0.333) 		1
(1.00) 		0.311
(0.652) 		0.9
(1.00) 		0.0344
(0.222) 		0.0145
(0.13) 		0.66
(0.952) 		0.842
(1.00)
PPIG 16 (6%) 232 0.305
(0.647) 		0.0925
(0.356) 		0.00036
(0.0115) 		1
(1.00) 		0.903
(1.00) 		0.978
(1.00) 		0.189
(0.519) 		0.00252
(0.04) 		0.0666
(0.311) 		0.401
(0.747) 		0.653
(0.95) 		0.0841
(0.344)
MSN 15 (6%) 233 0.923
(1.00) 		0.211
(0.539) 		0.554
(0.865) 		0.181
(0.507) 		0.769
(1.00) 		0.163
(0.479) 		0.052
(0.272) 		0.0283
(0.196) 		0.148
(0.463) 		0.00978
(0.0988) 		0.0729
(0.326) 		0.066
(0.31)
MYOM1 23 (9%) 225 0.158
(0.473) 		0.0951
(0.359) 		0.0544
(0.28) 		0.198
(0.527) 		0.705
(0.983) 		0.484
(0.818) 		0.158
(0.473) 		0.102
(0.373) 		0.192
(0.519) 		0.0157
(0.135) 		0.324
(0.661) 		0.0344
(0.222)
NOC3L 11 (4%) 237 0.857
(1.00) 		0.205
(0.53) 		0.0192
(0.15) 		0.676
(0.961) 		0.276
(0.633) 		0.728
(0.992) 		0.669
(0.956) 		0.00281
(0.0431) 		0.387
(0.733) 		0.118
(0.408) 		0.854
(1.00) 		0.081
(0.336)
NIPA2 8 (3%) 240 0.172
(0.496) 		0.819
(1.00) 		0.514
(0.835) 		0.147
(0.462) 		0.0125
(0.118) 		0.041
(0.24) 		0.063
(0.304) 		0.591
(0.894) 		0.211
(0.539) 		0.446
(0.782)
ZCCHC18 6 (2%) 242 0.0574
(0.287) 		0.309
(0.651) 		0.135
(0.443) 		0.105
(0.378) 		0.0107
(0.106) 		0.00489
(0.0618) 		0.0778
(0.333) 		0.198
(0.527)
LGMN 7 (3%) 241 0.508
(0.829) 		0.0765
(0.333) 		0.251
(0.603) 		0.314
(0.655) 		1
(1.00) 		0.0003
(0.0101) 		0.00103
(0.0236) 		0.177
(0.505) 		0.134
(0.443)
SSH2 12 (5%) 236 0.81
(1.00) 		0.0937
(0.356) 		0.00056
(0.0158) 		0.545
(0.86) 		0.906
(1.00) 		0.318
(0.656) 		0.0177
(0.144) 		0.346
(0.688) 		0.205
(0.53) 		0.924
(1.00) 		0.814
(1.00) 		0.19
(0.519)
EMR1 11 (4%) 237 0.0072
(0.0781) 		0.486
(0.82) 		0.403
(0.747) 		0.538
(0.853) 		0.15
(0.465) 		0.00097
(0.0227) 		0.0783
(0.333) 		0.791
(1.00) 		0.662
(0.952) 		0.0924
(0.356)
ZNF534 9 (4%) 239 0.0373
(0.228) 		0.138
(0.45) 		0.523
(0.843) 		1
(1.00) 		0.323
(0.661) 		0.00015
(0.00611) 		0.474
(0.81) 		0.814
(1.00)
PIK3CA 131 (53%) 117 0.938
(1.00) 		0.375
(0.717) 		0.266
(0.619) 		0.48
(0.817) 		0.036
(0.228) 		0.391
(0.736) 		0.1
(0.369) 		0.553
(0.865) 		0.597
(0.901) 		0.359
(0.701) 		0.418
(0.757) 		0.97
(1.00)
CCND1 14 (6%) 234 0.375
(0.717) 		0.811
(1.00) 		0.00196
(0.0346) 		0.534
(0.853) 		0.868
(1.00) 		0.795
(1.00) 		0.634
(0.93) 		0.0484
(0.261) 		0.115
(0.403) 		0.0923
(0.356) 		0.527
(0.847) 		0.439
(0.776)
ALG8 11 (4%) 237 1
(1.00) 		0.205
(0.53) 		0.155
(0.471) 		0.508
(0.83) 		0.0379
(0.229) 		0.396
(0.742) 		0.857
(1.00) 		0.172
(0.496) 		0.404
(0.748) 		0.0692
(0.318) 		0.21
(0.537) 		0.792
(1.00)
RBMX 12 (5%) 236 0.306
(0.648) 		0.0916
(0.356) 		0.0323
(0.213) 		1
(1.00) 		0.432
(0.77) 		0.751
(1.00) 		0.378
(0.72) 		0.111
(0.391) 		0.239
(0.586) 		0.692
(0.974) 		1
(1.00) 		0.445
(0.782)
INTS7 8 (3%) 240 0.502
(0.829) 		0.281
(0.633) 		0.0815
(0.336) 		0.204
(0.53) 		0.159
(0.474) 		0.0468
(0.259) 		0.00514
(0.0635) 		0.161
(0.476) 		0.0474
(0.261)
NAT1 7 (3%) 241 0.507
(0.829) 		0.0792
(0.334) 		0.155
(0.47) 		0.617
(0.916) 		1
(1.00) 		0.574
(0.88) 		0.00216
(0.0373) 		0.492
(0.828) 		0.793
(1.00)
JAKMIP2 12 (5%) 236 0.507
(0.829) 		0.284
(0.633) 		0.158
(0.473) 		0.82
(1.00) 		0.269
(0.622) 		0.105
(0.377) 		0.104
(0.377) 		0.00065
(0.0175) 		0.0865
(0.352) 		0.181
(0.507)
ING1 12 (5%) 236 0.0145
(0.13) 		0.887
(1.00) 		0.284
(0.633) 		0.676
(0.961) 		0.417
(0.757) 		0.0566
(0.285) 		0.541
(0.856) 		0.577
(0.882) 		0.298
(0.643) 		0.658
(0.95)
CCDC6 6 (2%) 242 0.564
(0.869) 		0.108
(0.384) 		0.514
(0.835) 		0.48
(0.817) 		0.945
(1.00) 		0.241
(0.589) 		0.703
(0.983) 		0.00797
(0.0849) 		0.625
(0.924) 		0.0601
(0.295)
EIF2S2 9 (4%) 239 0.0371
(0.228) 		0.85
(1.00) 		0.49
(0.825) 		0.159
(0.474) 		0.19
(0.519) 		0.375
(0.717) 		0.144
(0.459) 		0.316
(0.656) 		0.256
(0.608) 		0.558
(0.865)
RASA1 21 (8%) 227 0.641
(0.938) 		0.363
(0.702) 		0.00842
(0.0888) 		1
(1.00) 		0.995
(1.00) 		0.833
(1.00) 		0.324
(0.661) 		0.0605
(0.295) 		0.334
(0.674) 		0.693
(0.974) 		0.428
(0.767) 		0.085
(0.347)
DNER 18 (7%) 230 0.304
(0.647) 		0.0931
(0.356) 		0.147
(0.462) 		1
(1.00) 		0.248
(0.601) 		0.784
(1.00) 		0.116
(0.404) 		0.00035
(0.0115) 		0.239
(0.586) 		0.95
(1.00) 		0.942
(1.00) 		0.888
(1.00)
MSH6 17 (7%) 231 0.507
(0.829) 		0.286
(0.634) 		0.198
(0.527) 		1
(1.00) 		0.606
(0.908) 		0.516
(0.836) 		0.102
(0.373) 		0.00015
(0.00611) 		0.145
(0.459) 		0.446
(0.782) 		1
(1.00) 		0.561
(0.865)
C14ORF166B 9 (4%) 239 0.0585
(0.29) 		0.137
(0.45) 		0.733
(0.994) 		0.739
(0.997) 		0.343
(0.684) 		0.023
(0.17) 		0.522
(0.843) 		0.816
(1.00) 		1
(1.00) 		0.793
(1.00)
RAE1 11 (4%) 237 0.457
(0.79) 		0.078
(0.333) 		0.317
(0.656) 		0.507
(0.829) 		0.635
(0.931) 		0.678
(0.962) 		0.597
(0.901) 		0.0176
(0.144) 		0.167
(0.485) 		0.657
(0.95) 		0.143
(0.458) 		0.429
(0.769)
ZNF485 9 (4%) 239 1
(1.00) 		0.0792
(0.334) 		0.0008
(0.0199) 		1
(1.00) 		0.475
(0.81) 		0.316
(0.656) 		0.438
(0.774) 		0.409
(0.751) 		0.072
(0.324) 		0.281
(0.633)
AHCYL1 6 (2%) 242 0.294
(0.642) 		1
(1.00) 		0.929
(1.00) 		0.734
(0.994) 		0.458
(0.79) 		0.0116
(0.112) 		0.153
(0.468) 		0.434
(0.771)
MRPL47 6 (2%) 242 0.855
(1.00) 		0.535
(0.853) 		0.176
(0.503) 		1
(1.00) 		0.297
(0.642) 		0.507
(0.829) 		0.00618
(0.0713) 		0.0728
(0.326) 		0.471
(0.809) 		1
(1.00)
FILIP1 16 (6%) 232 0.556
(0.865) 		0.246
(0.6) 		0.163
(0.48) 		0.714
(0.984) 		0.287
(0.634) 		0.119
(0.409) 		0.146
(0.462) 		0.00224
(0.0376) 		0.715
(0.984) 		0.454
(0.788) 		0.922
(1.00) 		0.852
(1.00)
SLC1A3 12 (5%) 236 0.163
(0.48) 		0.763
(1.00) 		0.342
(0.684) 		0.396
(0.742) 		0.356
(0.701) 		0.0308
(0.208) 		0.807
(1.00) 		0.644
(0.943) 		0.61
(0.91) 		0.1
(0.369)
WBP4 8 (3%) 240 0.0797
(0.334) 		0.297
(0.643) 		0.0519
(0.272) 		0.872
(1.00) 		0.212
(0.539) 		0.00077
(0.0194) 		0.697
(0.977) 		0.0929
(0.356) 		0.857
(1.00) 		0.0806
(0.335)
TRIM59 9 (4%) 239 0.055
(0.281) 		0.851
(1.00) 		0.717
(0.985) 		0.909
(1.00) 		0.477
(0.813) 		0.0765
(0.333) 		0.693
(0.974) 		0.814
(1.00) 		0.423
(0.761) 		0.022
(0.164)
RSBN1L 12 (5%) 236 0.191
(0.519) 		0.0915
(0.356) 		0.263
(0.615) 		0.817
(1.00) 		0.737
(0.996) 		0.213
(0.539) 		0.255
(0.606) 		0.00411
(0.0555) 		0.0824
(0.339) 		0.419
(0.758)
ERBB3 17 (7%) 231 0.781
(1.00) 		0.556
(0.865) 		0.864
(1.00) 		0.038
(0.229) 		0.556
(0.865) 		0.274
(0.632) 		0.196
(0.527) 		0.949
(1.00) 		0.549
(0.863) 		0.886
(1.00)
C1ORF100 9 (4%) 239 0.504
(0.829) 		0.283
(0.633) 		0.494
(0.829) 		0.786
(1.00) 		0.746
(1.00) 		0.32
(0.659) 		0.203
(0.53) 		0.0139
(0.126) 		0.154
(0.47) 		0.129
(0.43)
RHBDD3 4 (2%) 244 0.453
(0.788) 		0.309
(0.651) 		0.507
(0.829) 		0.105
(0.378) 		0.12
(0.41) 		0.0244
(0.177) 		0.0868
(0.353) 		0.0828
(0.34)
NAA15 14 (6%) 234 0.552
(0.865) 		0.25
(0.602) 		0.536
(0.853) 		0.0751
(0.332) 		0.425
(0.763) 		0.484
(0.818) 		0.147
(0.462) 		0.00107
(0.0236) 		0.0693
(0.318) 		0.311
(0.652) 		0.165
(0.483) 		0.156
(0.472)
MLH3 17 (7%) 231 1
(1.00) 		0.0484
(0.261) 		0.00086
(0.021) 		1
(1.00) 		0.492
(0.827) 		0.561
(0.865) 		0.212
(0.539) 		0.0532
(0.276) 		0.22
(0.554) 		0.894
(1.00) 		0.943
(1.00) 		0.778
(1.00)
TTC39C 7 (3%) 241 0.854
(1.00) 		0.205
(0.53) 		0.0571
(0.286) 		0.152
(0.468) 		0.235
(0.581) 		0.129
(0.43) 		0.0266
(0.189) 		0.82
(1.00) 		0.58
(0.885)
GPRASP1 21 (8%) 227 0.442
(0.779) 		0.0443
(0.251) 		0.0159
(0.135) 		0.919
(1.00) 		0.81
(1.00) 		0.429
(0.769) 		0.235
(0.581) 		0.112
(0.396) 		0.0836
(0.342) 		0.762
(1.00) 		0.897
(1.00) 		0.777
(1.00)
ZNF674 14 (6%) 234 0.089
(0.356) 		0.484
(0.818) 		0.498
(0.829) 		0.179
(0.507) 		0.351
(0.693) 		0.00206
(0.0361) 		0.271
(0.626) 		0.286
(0.634) 		1
(1.00) 		0.559
(0.865)
TXNRD1 8 (3%) 240 0.855
(1.00) 		0.204
(0.53) 		0.73
(0.993) 		0.682
(0.965) 		0.528
(0.847) 		0.302
(0.647) 		0.266
(0.619) 		0.0364
(0.228) 		0.418
(0.757) 		0.238
(0.585)
LETMD1 6 (2%) 242 0.505
(0.829) 		0.285
(0.634) 		0.838
(1.00) 		0.505
(0.829) 		0.733
(0.994) 		0.141
(0.456) 		0.0037
(0.0518) 		0.073
(0.326) 		0.108
(0.387)
ATP6V1C2 12 (5%) 236 0.0458
(0.256) 		0.295
(0.642) 		0.305
(0.647) 		0.409
(0.751) 		0.153
(0.468) 		0.0434
(0.248) 		0.473
(0.809) 		0.254
(0.606) 		0.924
(1.00) 		0.708
(0.983)
CCDC150 11 (4%) 237 0.00356
(0.0504) 		0.409
(0.751) 		0.105
(0.378) 		0.054
(0.28) 		0.155
(0.471) 		0.0635
(0.305) 		0.179
(0.507) 		0.918
(1.00) 		0.607
(0.909) 		0.66
(0.952)
OR8B8 7 (3%) 241 0.129
(0.43) 		1
(1.00) 		0.376
(0.717) 		0.419
(0.758) 		0.573
(0.879) 		0.00489
(0.0618) 		0.537
(0.853) 		0.611
(0.91)
NRIP1 13 (5%) 235 0.503
(0.829) 		0.0778
(0.333) 		0.0881
(0.356) 		0.885
(1.00) 		0.206
(0.531) 		0.22
(0.553) 		0.527
(0.847) 		0.00053
(0.0157) 		0.278
(0.633) 		0.288
(0.634) 		0.924
(1.00) 		0.301
(0.647)
MCTP1 13 (5%) 235 0.504
(0.829) 		0.226
(0.565) 		0.0493
(0.263) 		0.764
(1.00) 		0.907
(1.00) 		0.73
(0.993) 		0.939
(1.00) 		0.0218
(0.163) 		0.141
(0.456) 		0.693
(0.974) 		0.423
(0.761) 		0.0928
(0.356)
ZNF620 9 (4%) 239 0.106
(0.38) 		1
(1.00) 		0.0367
(0.228) 		0.416
(0.756) 		0.449
(0.785) 		0.0617
(0.299) 		0.91
(1.00) 		0.378
(0.719) 		0.662
(0.952) 		0.0662
(0.31)
RIOK3 9 (4%) 239 0.0588
(0.291) 		0.859
(1.00) 		0.698
(0.977) 		0.908
(1.00) 		0.321
(0.66) 		0.0149
(0.131) 		0.296
(0.642) 		0.653
(0.95) 		0.814
(1.00) 		0.557
(0.865)
GFAP 6 (2%) 242 0.12
(0.41) 		0.818
(1.00) 		0.153
(0.468) 		0.198
(0.527) 		0.0513
(0.27) 		0.0165
(0.139) 		0.249
(0.601) 		0.109
(0.389)
C3AR1 7 (3%) 241 0.505
(0.829) 		0.282
(0.633) 		0.0255
(0.183) 		0.589
(0.891) 		0.938
(1.00) 		0.296
(0.642) 		0.167
(0.485) 		0.398
(0.745) 		1
(1.00)
STK3 10 (4%) 238 0.385
(0.731) 		0.311
(0.652) 		0.476
(0.812) 		0.587
(0.889) 		0.941
(1.00) 		0.0274
(0.192) 		0.987
(1.00) 		0.551
(0.865) 		0.774
(1.00) 		0.661
(0.952)
ZNF385B 7 (3%) 241 0.0577
(0.287) 		0.852
(1.00) 		0.0987
(0.368) 		0.506
(0.829) 		0.437
(0.774) 		0.0267
(0.189) 		0.467
(0.804) 		0.576
(0.881)
ATF6 14 (6%) 234 0.416
(0.756) 		0.191
(0.519) 		0.0218
(0.163) 		1
(1.00) 		0.645
(0.943) 		0.365
(0.704) 		0.074
(0.328) 		0.151
(0.467) 		0.101
(0.372) 		0.287
(0.634) 		0.0954
(0.359) 		0.0995
(0.369)
ZNF774 10 (4%) 238 0.0337
(0.219) 		0.763
(1.00) 		0.211
(0.538) 		0.711
(0.983) 		0.557
(0.865) 		0.13
(0.431) 		0.583
(0.887) 		0.657
(0.95) 		0.878
(1.00) 		0.155
(0.471)
PARG 9 (4%) 239 0.0561
(0.283) 		1
(1.00) 		0.627
(0.924) 		0.609
(0.91) 		0.37
(0.71) 		0.00848
(0.0888) 		0.317
(0.656) 		0.282
(0.633) 		0.15
(0.465) 		0.0927
(0.356)
PSMD3 11 (4%) 237 0.855
(1.00) 		0.205
(0.53) 		0.0898
(0.356) 		0.433
(0.77) 		0.794
(1.00) 		0.393
(0.74) 		0.313
(0.655) 		0.0178
(0.144) 		0.0785
(0.333) 		0.535
(0.853) 		0.664
(0.952) 		0.559
(0.865)
STRN3 12 (5%) 236 0.051
(0.269) 		0.886
(1.00) 		0.705
(0.983) 		0.734
(0.994) 		0.245
(0.597) 		0.0497
(0.264) 		0.11
(0.39) 		0.158
(0.473) 		0.0768
(0.333) 		0.0291
(0.2)
MAPK8 11 (4%) 237 0.622
(0.921) 		0.402
(0.747) 		0.316
(0.656) 		0.256
(0.608) 		0.733
(0.994) 		0.612
(0.91) 		0.18
(0.507) 		0.0426
(0.246) 		0.771
(1.00) 		0.602
(0.905) 		0.377
(0.718) 		0.0656
(0.309)
RBL2 12 (5%) 236 0.554
(0.865) 		0.248
(0.601) 		0.0556
(0.282) 		0.85
(1.00) 		0.251
(0.603) 		0.731
(0.994) 		0.684
(0.967) 		0.00187
(0.0335) 		0.199
(0.527) 		0.12
(0.41) 		1
(1.00) 		0.259
(0.61)
PDGFRA 12 (5%) 236 0.265
(0.618) 		0.508
(0.829) 		0.115
(0.403) 		0.552
(0.865) 		0.432
(0.77) 		0.00054
(0.0158) 		0.618
(0.916) 		0.418
(0.757) 		0.857
(1.00) 		0.794
(1.00)
RG9MTD3 8 (3%) 240 0.323
(0.661) 		0.82
(1.00) 		0.739
(0.997) 		0.302
(0.647) 		0.233
(0.578) 		0.037
(0.228) 		0.515
(0.835) 		0.588
(0.89) 		0.536
(0.853) 		0.141
(0.456)
KANK4 11 (4%) 237 0.0378
(0.229) 		0.717
(0.985) 		0.0681
(0.315) 		0.396
(0.742) 		0.2
(0.53) 		0.136
(0.446) 		0.584
(0.887) 		0.338
(0.68) 		0.362
(0.702) 		0.413
(0.754)
ASXL2 14 (6%) 234 0.505
(0.829) 		0.284
(0.633) 		0.151
(0.467) 		0.717
(0.985) 		0.761
(1.00) 		0.663
(0.952) 		0.147
(0.462) 		0.00895
(0.092) 		0.407
(0.751) 		0.181
(0.507) 		0.733
(0.994) 		0.263
(0.614)
C14ORF118 13 (5%) 235 0.81
(1.00) 		0.0922
(0.356) 		2e-05
(0.00148) 		0.781
(1.00) 		0.168
(0.485) 		0.251
(0.603) 		0.421
(0.76) 		0.0864
(0.352) 		0.126
(0.423) 		0.806
(1.00) 		0.609
(0.91) 		0.56
(0.865)
THAP5 6 (2%) 242 0.184
(0.512) 		0.138
(0.451) 		0.117
(0.405) 		0.735
(0.994) 		0.483
(0.818) 		0.00543
(0.0649) 		0.605
(0.908) 		0.302
(0.647)
PRKCE 9 (4%) 239 0.0992
(0.369) 		0.409
(0.751) 		0.565
(0.87) 		0.521
(0.843) 		0.45
(0.785) 		0.0153
(0.133) 		0.287
(0.634) 		0.499
(0.829) 		0.859
(1.00) 		0.795
(1.00)
OR5AK2 5 (2%) 243 0.388
(0.733) 		0.409
(0.751) 		0.319
(0.657) 		0.316
(0.656) 		0.0199
(0.152) 		0.0877
(0.355) 		0.202
(0.53)
C1ORF101 12 (5%) 236 0.81
(1.00) 		0.323
(0.661) 		0.00857
(0.0889) 		0.546
(0.861) 		0.632
(0.93) 		1
(1.00) 		0.741
(0.998) 		0.707
(0.983) 		0.0778
(0.333) 		0.417
(0.756) 		0.208
(0.535) 		0.142
(0.458)
SPOP 21 (8%) 227 0.147
(0.462) 		0.677
(0.962) 		0.411
(0.751) 		0.266
(0.619) 		0.92
(1.00) 		0.424
(0.762) 		0.348
(0.689) 		0.11
(0.391) 		0.143
(0.458) 		0.613
(0.91) 		0.334
(0.674) 		0.362
(0.702)
FGFR2 31 (12%) 217 0.641
(0.938) 		0.366
(0.706) 		0.0549
(0.281) 		0.891
(1.00) 		0.992
(1.00) 		0.713
(0.983) 		0.708
(0.983) 		0.0759
(0.333) 		0.532
(0.852) 		0.415
(0.755) 		0.712
(0.983) 		0.879
(1.00)
MAX 9 (4%) 239 0.0679
(0.315) 		1
(1.00) 		0.78
(1.00) 		0.718
(0.985) 		0.121
(0.411) 		0.288
(0.634) 		0.971
(1.00) 		0.695
(0.976) 		1
(1.00) 		0.686
(0.969)
NRAS 9 (4%) 239 0.259
(0.61) 		0.554
(0.865) 		0.0484
(0.261) 		0.592
(0.894) 		0.864
(1.00) 		0.816
(1.00) 		0.764
(1.00)
C9ORF23 9 (4%) 239 0.142
(0.458) 		0.215
(0.543) 		0.617
(0.916) 		0.633
(0.93) 		0.343
(0.684) 		0.0798
(0.334) 		0.569
(0.875) 		0.764
(1.00) 		1
(1.00) 		0.659
(0.952)
WDR45 11 (4%) 237 0.224
(0.561) 		0.572
(0.877) 		0.967
(1.00) 		0.584
(0.887) 		0.529
(0.849) 		0.24
(0.588) 		0.71
(0.983) 		0.668
(0.956) 		0.0585
(0.29) 		0.259
(0.61)
RRAS2 4 (2%) 244 0.113
(0.398) 		0.51
(0.83) 		0.204
(0.53) 		0.541
(0.857) 		0.217
(0.548) 		0.669
(0.956) 		0.822
(1.00)
SERHL2 6 (2%) 242 0.235
(0.581) 		0.819
(1.00) 		0.876
(1.00) 		0.939
(1.00) 		0.327
(0.664) 		0.345
(0.687) 		0.816
(1.00) 		0.449
(0.785) 		0.371
(0.712) 		0.681
(0.964)
OR52I2 8 (3%) 240 0.855
(1.00) 		0.531
(0.851) 		0.469
(0.806) 		0.139
(0.451) 		0.294
(0.642) 		0.776
(1.00) 		0.92
(1.00) 		0.0979
(0.366) 		0.144
(0.459) 		0.793
(1.00) 		1
(1.00) 		0.446
(0.782)
SGK1 13 (5%) 235 0.505
(0.829) 		0.283
(0.633) 		0.326
(0.663) 		0.676
(0.961) 		0.724
(0.991) 		1
(1.00) 		0.0492
(0.262) 		0.347
(0.688) 		0.165
(0.483) 		0.0638
(0.306)
SLC44A3 6 (2%) 242 0.296
(0.642) 		0.338
(0.68) 		0.466
(0.802) 		0.938
(1.00) 		0.728
(0.992) 		0.251
(0.603) 		0.704
(0.983) 		1
(1.00)
LIMK2 12 (5%) 236 0.262
(0.614) 		0.452
(0.787) 		0.265
(0.619) 		0.765
(1.00) 		0.67
(0.956) 		0.214
(0.542) 		0.104
(0.377) 		0.306
(0.648) 		0.188
(0.519) 		0.329
(0.669) 		0.727
(0.992) 		0.604
(0.907)
SFRP4 8 (3%) 240 0.504
(0.829) 		0.283
(0.633) 		0.122
(0.413) 		0.42
(0.759) 		0.825
(1.00) 		0.094
(0.356) 		0.484
(0.818) 		0.0605
(0.295) 		0.536
(0.853) 		0.431
(0.77)
RASSF9 9 (4%) 239 0.0759
(0.333) 		1
(1.00) 		0.347
(0.688) 		0.706
(0.983) 		0.849
(1.00) 		0.0486
(0.262) 		0.695
(0.976) 		0.166
(0.483)
MECOM 12 (5%) 236 0.557
(0.865) 		0.0482
(0.261) 		0.0803
(0.335) 		0.537
(0.853) 		0.756
(1.00) 		0.401
(0.747) 		0.0938
(0.356) 		0.258
(0.61) 		0.444
(0.782) 		0.576
(0.881) 		0.54
(0.856) 		1
(1.00)
WDR65 6 (2%) 242 0.119
(0.409) 		0.849
(1.00) 		0.183
(0.51) 		0.611
(0.91) 		0.727
(0.992) 		0.0889
(0.356) 		0.935
(1.00) 		0.435
(0.771) 		0.729
(0.993) 		0.794
(1.00)
OMA1 10 (4%) 238 0.0594
(0.292) 		0.858
(1.00) 		0.454
(0.788) 		1
(1.00) 		0.571
(0.877) 		0.0522
(0.273) 		0.872
(1.00) 		0.119
(0.409) 		1
(1.00) 		0.261
(0.613)
EPC2 5 (2%) 243 0.316
(0.656) 		1
(1.00) 		0.346
(0.688) 		1
(1.00) 		0.334
(0.674) 		0.184
(0.512) 		0.626
(0.924) 		0.449
(0.785) 		1
(1.00) 		0.445
(0.782)
EPS8 12 (5%) 236 0.39
(0.734) 		0.41
(0.751) 		0.976
(1.00) 		0.9
(1.00) 		0.684
(0.967) 		0.171
(0.493) 		0.809
(1.00) 		0.278
(0.633) 		0.878
(1.00) 		0.261
(0.613)
EFCAB4B 11 (4%) 237 0.352
(0.694) 		0.482
(0.818) 		0.125
(0.422) 		0.585
(0.888) 		0.923
(1.00) 		0.0546
(0.28) 		0.988
(1.00) 		0.0678
(0.315) 		0.328
(0.667) 		0.0936
(0.356)
NPRL2 5 (2%) 243 0.0542
(0.28) 		0.931
(1.00) 		0.158
(0.473) 		1
(1.00) 		0.536
(0.853) 		0.649
(0.946) 		0.621
(0.92)
MUTED 7 (3%) 241 0.0798
(0.334) 		0.441
(0.778) 		0.679
(0.964) 		0.374
(0.717) 		0.294
(0.642) 		0.114
(0.398) 		0.844
(1.00) 		0.764
(1.00)
TPX2 6 (2%) 242 0.118
(0.409) 		0.548
(0.862) 		0.15
(0.465) 		0.196
(0.527) 		0.247
(0.601) 		0.159
(0.474) 		0.247
(0.601) 		0.134
(0.443) 		0.21
(0.537) 		0.143
(0.459)
TMEM62 9 (4%) 239 0.0607
(0.295) 		1
(1.00) 		0.475
(0.81) 		1
(1.00) 		0.451
(0.786) 		0.0462
(0.257) 		0.451
(0.786) 		0.336
(0.678)
B3GALT5 4 (2%) 244 0.126
(0.423) 		0.345
(0.687) 		0.12
(0.41) 		0.681
(0.964) 		0.422
(0.761) 		0.888
(1.00) 		0.822
(1.00)
NSUN4 6 (2%) 242 0.167
(0.485) 		0.0545
(0.28) 		0.704
(0.983) 		1
(1.00) 		0.718
(0.985) 		1
(1.00) 		0.849
(1.00) 		0.0814
(0.336) 		0.566
(0.87) 		0.851
(1.00)
CHD4 35 (14%) 213 0.0491
(0.262) 		0.339
(0.681) 		0.309
(0.651) 		0.9
(1.00) 		0.524
(0.843) 		0.634
(0.93) 		0.883
(1.00) 		0.33
(0.669) 		0.408
(0.751) 		0.823
(1.00) 		0.551
(0.865) 		0.721
(0.988)
FCN1 7 (3%) 241 0.057
(0.286) 		0.82
(1.00) 		0.957
(1.00) 		0.794
(1.00) 		0.576
(0.881) 		0.397
(0.744) 		0.27
(0.623) 		0.434
(0.771)
'PTEN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0016 (Fisher's exact test), Q value = 0.031

Table S1.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PTEN MUTATED 12 6 11 4
PTEN WILD-TYPE 1 12 2 3

Figure S1.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'PTEN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S2.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PTEN MUTATED 8 0 6 7 12
PTEN WILD-TYPE 4 10 1 0 3

Figure S2.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S3.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PTEN MUTATED 14 73 46 23
PTEN WILD-TYPE 57 14 8 7

Figure S3.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PTEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S4.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PTEN MUTATED 11 17 53
PTEN WILD-TYPE 33 11 10

Figure S4.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PTEN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00111 (Fisher's exact test), Q value = 0.024

Table S5.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PTEN MUTATED 20 40 21 9 7 21 14
PTEN WILD-TYPE 4 10 10 10 15 12 10

Figure S5.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'PTEN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S6.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PTEN MUTATED 59 34 22 17
PTEN WILD-TYPE 9 44 9 9

Figure S6.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S7.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PTEN MUTATED 10 57 25 68
PTEN WILD-TYPE 54 16 11 6

Figure S7.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S8.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PTEN MUTATED 3 33 5 28 21 29 41
PTEN WILD-TYPE 41 8 12 5 14 2 5

Figure S8.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S9.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PTEN MUTATED 6 25 47 69 11
PTEN WILD-TYPE 35 15 17 6 9

Figure S9.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S10.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PTEN MUTATED 76 8 74
PTEN WILD-TYPE 28 47 7

Figure S10.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0019

Table S11.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PTEN MUTATED 5 40 11 11
PTEN WILD-TYPE 9 7 10 19

Figure S11.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S12.  Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PTEN MUTATED 11 47 9
PTEN WILD-TYPE 23 6 16

Figure S12.  Get High-res Image Gene #1: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0735 (Fisher's exact test), Q value = 0.33

Table S13.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PIK3R1 MUTATED 5 2 7 2
PIK3R1 WILD-TYPE 8 16 6 5
'PIK3R1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0607 (Fisher's exact test), Q value = 0.3

Table S14.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PIK3R1 MUTATED 3 0 4 3 6
PIK3R1 WILD-TYPE 9 10 3 4 9
'PIK3R1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0085 (Fisher's exact test), Q value = 0.089

Table S15.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PIK3R1 MUTATED 13 36 22 10
PIK3R1 WILD-TYPE 58 51 32 20

Figure S13.  Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PIK3R1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 2e-04 (Fisher's exact test), Q value = 0.0075

Table S16.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PIK3R1 MUTATED 6 7 32
PIK3R1 WILD-TYPE 38 21 31

Figure S14.  Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PIK3R1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S17.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PIK3R1 MUTATED 9 21 10 7 6 11 6
PIK3R1 WILD-TYPE 15 29 21 12 16 22 18
'PIK3R1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.4

Table S18.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PIK3R1 MUTATED 31 23 10 6
PIK3R1 WILD-TYPE 37 55 21 20
'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 5e-05 (Fisher's exact test), Q value = 0.0027

Table S19.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PIK3R1 MUTATED 7 29 15 31
PIK3R1 WILD-TYPE 57 44 21 43

Figure S15.  Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 2e-04 (Fisher's exact test), Q value = 0.0075

Table S20.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PIK3R1 MUTATED 3 16 3 15 11 14 20
PIK3R1 WILD-TYPE 41 25 14 18 24 17 26

Figure S16.  Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0124 (Fisher's exact test), Q value = 0.12

Table S21.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PIK3R1 MUTATED 5 15 28 26 6
PIK3R1 WILD-TYPE 36 25 36 49 14

Figure S17.  Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00055 (Fisher's exact test), Q value = 0.016

Table S22.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PIK3R1 MUTATED 41 7 32
PIK3R1 WILD-TYPE 63 48 49

Figure S18.  Get High-res Image Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 0.91

Table S23.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PIK3R1 MUTATED 3 18 6 8
PIK3R1 WILD-TYPE 11 29 15 22
'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.093 (Fisher's exact test), Q value = 0.36

Table S24.  Gene #2: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PIK3R1 MUTATED 6 21 8
PIK3R1 WILD-TYPE 28 32 17
'TP53 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 4e-05 (Fisher's exact test), Q value = 0.0023

Table S25.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
TP53 MUTATED 2 13 1 0
TP53 WILD-TYPE 11 5 12 7

Figure S19.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'TP53 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.0015

Table S26.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
TP53 MUTATED 4 10 1 1 0
TP53 WILD-TYPE 8 0 6 6 15

Figure S20.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S27.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TP53 MUTATED 55 7 5 1
TP53 WILD-TYPE 16 80 49 29

Figure S21.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S28.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TP53 MUTATED 28 7 5
TP53 WILD-TYPE 16 21 58

Figure S22.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S29.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TP53 MUTATED 4 0 10 10 17 8 9
TP53 WILD-TYPE 20 50 21 9 5 25 15

Figure S23.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S30.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TP53 MUTATED 4 39 9 6
TP53 WILD-TYPE 64 39 22 20

Figure S24.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S31.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TP53 MUTATED 51 7 8 3
TP53 WILD-TYPE 13 66 28 71

Figure S25.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S32.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TP53 MUTATED 38 0 11 4 12 3 1
TP53 WILD-TYPE 6 41 6 29 23 28 45

Figure S26.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S33.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TP53 MUTATED 35 4 15 5 5
TP53 WILD-TYPE 6 36 49 70 15

Figure S27.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S34.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TP53 MUTATED 20 41 3
TP53 WILD-TYPE 84 14 78

Figure S28.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S35.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
TP53 MUTATED 10 4 4 18
TP53 WILD-TYPE 4 43 17 12

Figure S29.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S36.  Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
TP53 MUTATED 24 5 7
TP53 WILD-TYPE 10 48 18

Figure S30.  Get High-res Image Gene #3: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0723 (Fisher's exact test), Q value = 0.32

Table S37.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CTCF MUTATED 3 1 5 0
CTCF WILD-TYPE 10 17 8 7
'CTCF MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.202 (Fisher's exact test), Q value = 0.53

Table S38.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CTCF MUTATED 3 0 3 1 2
CTCF WILD-TYPE 9 10 4 6 13
'CTCF MUTATION STATUS' versus 'CN_CNMF'

P value = 4e-05 (Fisher's exact test), Q value = 0.0023

Table S39.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CTCF MUTATED 1 23 12 5
CTCF WILD-TYPE 70 64 42 25

Figure S31.  Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CTCF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 0.44

Table S40.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CTCF MUTATED 3 6 12
CTCF WILD-TYPE 41 22 51
'CTCF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 0.89

Table S41.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CTCF MUTATED 5 12 4 4 2 5 2
CTCF WILD-TYPE 19 38 27 15 20 28 22
'CTCF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0234 (Fisher's exact test), Q value = 0.17

Table S42.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CTCF MUTATED 19 8 5 2
CTCF WILD-TYPE 49 70 26 24

Figure S32.  Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00066 (Fisher's exact test), Q value = 0.018

Table S43.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CTCF MUTATED 2 16 6 20
CTCF WILD-TYPE 62 57 30 54

Figure S33.  Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'CTCF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00105 (Fisher's exact test), Q value = 0.024

Table S44.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CTCF MUTATED 0 8 3 7 4 8 14
CTCF WILD-TYPE 44 33 14 26 31 23 32

Figure S34.  Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00046 (Fisher's exact test), Q value = 0.014

Table S45.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CTCF MUTATED 0 6 16 20 2
CTCF WILD-TYPE 41 34 48 55 18

Figure S35.  Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CTCF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0184 (Fisher's exact test), Q value = 0.15

Table S46.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CTCF MUTATED 19 4 21
CTCF WILD-TYPE 85 51 60

Figure S36.  Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0269 (Fisher's exact test), Q value = 0.19

Table S47.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CTCF MUTATED 0 11 2 1
CTCF WILD-TYPE 14 36 19 29

Figure S37.  Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'CTCF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0101 (Fisher's exact test), Q value = 0.1

Table S48.  Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CTCF MUTATED 1 12 1
CTCF WILD-TYPE 33 41 24

Figure S38.  Get High-res Image Gene #4: 'CTCF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'FBXW7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.701 (Fisher's exact test), Q value = 0.98

Table S49.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
FBXW7 MUTATED 3 4 3 0
FBXW7 WILD-TYPE 10 14 10 7
'FBXW7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 0.62

Table S50.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
FBXW7 MUTATED 2 3 3 1 1
FBXW7 WILD-TYPE 10 7 4 6 14
'FBXW7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0776 (Fisher's exact test), Q value = 0.33

Table S51.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FBXW7 MUTATED 13 18 3 4
FBXW7 WILD-TYPE 58 69 51 26
'FBXW7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 0.5

Table S52.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
FBXW7 MUTATED 11 3 8
FBXW7 WILD-TYPE 33 25 55
'FBXW7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 0.73

Table S53.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FBXW7 MUTATED 4 5 3 3 6 7 6
FBXW7 WILD-TYPE 20 45 28 16 16 26 18
'FBXW7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.474 (Fisher's exact test), Q value = 0.81

Table S54.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FBXW7 MUTATED 8 14 6 6
FBXW7 WILD-TYPE 60 64 25 20
'FBXW7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0169 (Fisher's exact test), Q value = 0.14

Table S55.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FBXW7 MUTATED 14 6 10 8
FBXW7 WILD-TYPE 50 67 26 66

Figure S39.  Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'FBXW7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.003 (Fisher's exact test), Q value = 0.045

Table S56.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FBXW7 MUTATED 12 0 4 8 5 3 6
FBXW7 WILD-TYPE 32 41 13 25 30 28 40

Figure S40.  Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FBXW7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0157 (Fisher's exact test), Q value = 0.14

Table S57.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FBXW7 MUTATED 9 1 12 7 5
FBXW7 WILD-TYPE 32 39 52 68 15

Figure S41.  Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'FBXW7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0757 (Fisher's exact test), Q value = 0.33

Table S58.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FBXW7 MUTATED 13 13 8
FBXW7 WILD-TYPE 91 42 73
'FBXW7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00847 (Fisher's exact test), Q value = 0.089

Table S59.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
FBXW7 MUTATED 0 4 2 10
FBXW7 WILD-TYPE 14 43 19 20

Figure S42.  Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'FBXW7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0373 (Fisher's exact test), Q value = 0.23

Table S60.  Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
FBXW7 MUTATED 8 3 5
FBXW7 WILD-TYPE 26 50 20

Figure S43.  Get High-res Image Gene #5: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S61.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PIK3CA MUTATED 7 8 7 4
PIK3CA WILD-TYPE 6 10 6 3
'PIK3CA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.375 (Fisher's exact test), Q value = 0.72

Table S62.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PIK3CA MUTATED 5 4 6 3 8
PIK3CA WILD-TYPE 7 6 1 4 7
'PIK3CA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.266 (Fisher's exact test), Q value = 0.62

Table S63.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PIK3CA MUTATED 34 51 30 12
PIK3CA WILD-TYPE 37 36 24 18
'PIK3CA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.48 (Fisher's exact test), Q value = 0.82

Table S64.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PIK3CA MUTATED 20 17 32
PIK3CA WILD-TYPE 24 11 31
'PIK3CA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.036 (Fisher's exact test), Q value = 0.23

Table S65.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PIK3CA MUTATED 14 22 21 6 12 13 17
PIK3CA WILD-TYPE 10 28 10 13 10 20 7

Figure S44.  Get High-res Image Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'PIK3CA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.391 (Fisher's exact test), Q value = 0.74

Table S66.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PIK3CA MUTATED 35 36 17 17
PIK3CA WILD-TYPE 33 42 14 9
'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.1 (Fisher's exact test), Q value = 0.37

Table S67.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PIK3CA MUTATED 28 37 25 40
PIK3CA WILD-TYPE 36 36 11 34
'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 0.87

Table S68.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PIK3CA MUTATED 21 22 6 17 23 17 24
PIK3CA WILD-TYPE 23 19 11 16 12 14 22
'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 0.9

Table S69.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PIK3CA MUTATED 19 19 34 45 10
PIK3CA WILD-TYPE 22 21 30 30 10
'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 0.7

Table S70.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PIK3CA MUTATED 55 25 47
PIK3CA WILD-TYPE 49 30 34
'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 0.76

Table S71.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PIK3CA MUTATED 8 28 9 13
PIK3CA WILD-TYPE 6 19 12 17
'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.97 (Fisher's exact test), Q value = 1

Table S72.  Gene #6: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PIK3CA MUTATED 17 28 13
PIK3CA WILD-TYPE 17 25 12
'ARID1A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 0.63

Table S73.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ARID1A MUTATED 6 3 5 3
ARID1A WILD-TYPE 7 15 8 4
'ARID1A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.073 (Fisher's exact test), Q value = 0.33

Table S74.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ARID1A MUTATED 5 0 3 4 5
ARID1A WILD-TYPE 7 10 4 3 10
'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S75.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ARID1A MUTATED 7 43 19 11
ARID1A WILD-TYPE 64 44 35 19

Figure S45.  Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 0.91

Table S76.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ARID1A MUTATED 12 10 23
ARID1A WILD-TYPE 32 18 40
'ARID1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 0.79

Table S77.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ARID1A MUTATED 11 19 10 7 6 11 4
ARID1A WILD-TYPE 13 31 21 12 16 22 20
'ARID1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.308 (Fisher's exact test), Q value = 0.65

Table S78.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ARID1A MUTATED 28 23 11 6
ARID1A WILD-TYPE 40 55 20 20
'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00239 (Fisher's exact test), Q value = 0.039

Table S79.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ARID1A MUTATED 10 30 12 31
ARID1A WILD-TYPE 54 43 24 43

Figure S46.  Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S80.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ARID1A MUTATED 3 15 3 13 18 6 25
ARID1A WILD-TYPE 41 26 14 20 17 25 21

Figure S47.  Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 5e-05 (Fisher's exact test), Q value = 0.0027

Table S81.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ARID1A MUTATED 3 9 26 34 8
ARID1A WILD-TYPE 38 31 38 41 12

Figure S48.  Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00022 (Fisher's exact test), Q value = 0.0081

Table S82.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ARID1A MUTATED 36 7 37
ARID1A WILD-TYPE 68 48 44

Figure S49.  Get High-res Image Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 0.47

Table S83.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ARID1A MUTATED 3 21 9 7
ARID1A WILD-TYPE 11 26 12 23
'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.148 (Fisher's exact test), Q value = 0.46

Table S84.  Gene #7: 'ARID1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ARID1A MUTATED 9 24 7
ARID1A WILD-TYPE 25 29 18
'ARHGAP35 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.519 (Fisher's exact test), Q value = 0.84

Table S85.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ARHGAP35 MUTATED 4 5 3 0
ARHGAP35 WILD-TYPE 9 13 10 7
'ARHGAP35 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.889 (Fisher's exact test), Q value = 1

Table S86.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ARHGAP35 MUTATED 4 2 2 1 3
ARHGAP35 WILD-TYPE 8 8 5 6 12
'ARHGAP35 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 0.57

Table S87.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ARHGAP35 MUTATED 8 18 8 2
ARHGAP35 WILD-TYPE 63 69 46 28
'ARHGAP35 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S88.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ARHGAP35 MUTATED 6 3 10
ARHGAP35 WILD-TYPE 38 25 53
'ARHGAP35 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.58

Table S89.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ARHGAP35 MUTATED 2 4 5 4 5 9 3
ARHGAP35 WILD-TYPE 22 46 26 15 17 24 21
'ARHGAP35 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 0.64

Table S90.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ARHGAP35 MUTATED 7 15 7 3
ARHGAP35 WILD-TYPE 61 63 24 23
'ARHGAP35 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0316 (Fisher's exact test), Q value = 0.21

Table S91.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ARHGAP35 MUTATED 10 8 11 7
ARHGAP35 WILD-TYPE 54 65 25 67

Figure S50.  Get High-res Image Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ARHGAP35 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00701 (Fisher's exact test), Q value = 0.078

Table S92.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ARHGAP35 MUTATED 5 1 5 10 7 4 4
ARHGAP35 WILD-TYPE 39 40 12 23 28 27 42

Figure S51.  Get High-res Image Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ARHGAP35 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00235 (Fisher's exact test), Q value = 0.039

Table S93.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ARHGAP35 MUTATED 5 1 18 7 2
ARHGAP35 WILD-TYPE 36 39 46 68 18

Figure S52.  Get High-res Image Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ARHGAP35 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 0.79

Table S94.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ARHGAP35 MUTATED 16 9 8
ARHGAP35 WILD-TYPE 88 46 73
'ARHGAP35 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0431 (Fisher's exact test), Q value = 0.25

Table S95.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ARHGAP35 MUTATED 2 3 1 8
ARHGAP35 WILD-TYPE 12 44 20 22

Figure S53.  Get High-res Image Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'ARHGAP35 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.09 (Fisher's exact test), Q value = 0.36

Table S96.  Gene #8: 'ARHGAP35 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ARHGAP35 MUTATED 7 3 4
ARHGAP35 WILD-TYPE 27 50 21
'KRAS MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 0.52

Table S97.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
KRAS MUTATED 5 2 3 0
KRAS WILD-TYPE 8 16 10 7
'KRAS MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0362 (Fisher's exact test), Q value = 0.23

Table S98.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
KRAS MUTATED 3 0 3 3 1
KRAS WILD-TYPE 9 10 4 4 14

Figure S54.  Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'KRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00125 (Fisher's exact test), Q value = 0.026

Table S99.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
KRAS MUTATED 4 24 14 7
KRAS WILD-TYPE 67 63 40 23

Figure S55.  Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'KRAS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.63

Table S100.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
KRAS MUTATED 8 4 18
KRAS WILD-TYPE 36 24 45
'KRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00539 (Fisher's exact test), Q value = 0.065

Table S101.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
KRAS MUTATED 11 8 9 1 5 2 4
KRAS WILD-TYPE 13 42 22 18 17 31 20

Figure S56.  Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'KRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.371 (Fisher's exact test), Q value = 0.71

Table S102.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
KRAS MUTATED 16 11 8 5
KRAS WILD-TYPE 52 67 23 21
'KRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00185 (Fisher's exact test), Q value = 0.033

Table S103.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
KRAS MUTATED 7 11 15 19
KRAS WILD-TYPE 57 62 21 55

Figure S57.  Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'KRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00023 (Fisher's exact test), Q value = 0.0082

Table S104.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
KRAS MUTATED 4 2 1 13 10 10 12
KRAS WILD-TYPE 40 39 16 20 25 21 34

Figure S58.  Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'KRAS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S105.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
KRAS MUTATED 2 1 22 19 7
KRAS WILD-TYPE 39 39 42 56 13

Figure S59.  Get High-res Image Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'KRAS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.125 (Fisher's exact test), Q value = 0.42

Table S106.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
KRAS MUTATED 22 7 22
KRAS WILD-TYPE 82 48 59
'KRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 0.69

Table S107.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
KRAS MUTATED 1 10 7 7
KRAS WILD-TYPE 13 37 14 23
'KRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.223 (Fisher's exact test), Q value = 0.56

Table S108.  Gene #9: 'KRAS MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
KRAS MUTATED 4 14 7
KRAS WILD-TYPE 30 39 18
'CTNNB1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 8e-05 (Fisher's exact test), Q value = 0.0039

Table S109.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CTNNB1 MUTATED 1 3 6 7
CTNNB1 WILD-TYPE 12 15 7 0

Figure S60.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.0015

Table S110.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CTNNB1 MUTATED 4 0 1 0 12
CTNNB1 WILD-TYPE 8 10 6 7 3

Figure S61.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0019

Table S111.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CTNNB1 MUTATED 7 32 25 8
CTNNB1 WILD-TYPE 64 55 29 22

Figure S62.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00069 (Fisher's exact test), Q value = 0.018

Table S112.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CTNNB1 MUTATED 4 7 26
CTNNB1 WILD-TYPE 40 21 37

Figure S63.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'CTNNB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0019

Table S113.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CTNNB1 MUTATED 2 29 10 5 2 7 9
CTNNB1 WILD-TYPE 22 21 21 14 20 26 15

Figure S64.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'CTNNB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 0.54

Table S114.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CTNNB1 MUTATED 25 25 5 9
CTNNB1 WILD-TYPE 43 53 26 17
'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S115.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CTNNB1 MUTATED 3 53 5 13
CTNNB1 WILD-TYPE 61 20 31 61

Figure S65.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S116.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CTNNB1 MUTATED 0 39 1 7 14 10 3
CTNNB1 WILD-TYPE 44 2 16 26 21 21 43

Figure S66.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S117.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CTNNB1 MUTATED 1 32 19 13 6
CTNNB1 WILD-TYPE 40 8 45 62 14

Figure S67.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S118.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CTNNB1 MUTATED 59 1 11
CTNNB1 WILD-TYPE 45 54 70

Figure S68.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00707 (Fisher's exact test), Q value = 0.078

Table S119.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CTNNB1 MUTATED 0 14 8 3
CTNNB1 WILD-TYPE 14 33 13 27

Figure S69.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00122 (Fisher's exact test), Q value = 0.026

Table S120.  Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CTNNB1 MUTATED 1 18 6
CTNNB1 WILD-TYPE 33 35 19

Figure S70.  Get High-res Image Gene #10: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ZFHX3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.171 (Fisher's exact test), Q value = 0.49

Table S121.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZFHX3 MUTATED 7 6 2 1
ZFHX3 WILD-TYPE 6 12 11 6
'ZFHX3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.51

Table S122.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZFHX3 MUTATED 4 2 2 5 3
ZFHX3 WILD-TYPE 8 8 5 2 12
'ZFHX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00487 (Fisher's exact test), Q value = 0.062

Table S123.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZFHX3 MUTATED 4 23 10 5
ZFHX3 WILD-TYPE 67 64 44 25

Figure S71.  Get High-res Image Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZFHX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0159 (Fisher's exact test), Q value = 0.14

Table S124.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZFHX3 MUTATED 5 0 13
ZFHX3 WILD-TYPE 39 28 50

Figure S72.  Get High-res Image Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'ZFHX3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S125.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZFHX3 MUTATED 4 8 9 5 3 2 4
ZFHX3 WILD-TYPE 20 42 22 14 19 31 20
'ZFHX3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S126.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZFHX3 MUTATED 10 14 7 4
ZFHX3 WILD-TYPE 58 64 24 22
'ZFHX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S127.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZFHX3 MUTATED 9 14 8 13
ZFHX3 WILD-TYPE 55 59 28 61
'ZFHX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00688 (Fisher's exact test), Q value = 0.077

Table S128.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZFHX3 MUTATED 4 3 2 12 11 4 8
ZFHX3 WILD-TYPE 40 38 15 21 24 27 38

Figure S73.  Get High-res Image Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZFHX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 0.45

Table S129.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZFHX3 MUTATED 4 4 17 12 4
ZFHX3 WILD-TYPE 37 36 47 63 16
'ZFHX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.179 (Fisher's exact test), Q value = 0.51

Table S130.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZFHX3 MUTATED 21 5 15
ZFHX3 WILD-TYPE 83 50 66
'ZFHX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.578 (Fisher's exact test), Q value = 0.88

Table S131.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZFHX3 MUTATED 2 4 4 5
ZFHX3 WILD-TYPE 12 43 17 25
'ZFHX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 0.78

Table S132.  Gene #11: 'ZFHX3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZFHX3 MUTATED 6 5 4
ZFHX3 WILD-TYPE 28 48 21
'SPOP MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.46

Table S133.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
SPOP MUTATED 2 1 0 2
SPOP WILD-TYPE 11 17 13 5
'SPOP MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.677 (Fisher's exact test), Q value = 0.96

Table S134.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
SPOP MUTATED 0 1 1 1 2
SPOP WILD-TYPE 12 9 6 6 13
'SPOP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 0.75

Table S135.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SPOP MUTATED 4 10 6 1
SPOP WILD-TYPE 67 77 48 29
'SPOP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.266 (Fisher's exact test), Q value = 0.62

Table S136.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SPOP MUTATED 4 0 6
SPOP WILD-TYPE 40 28 57
'SPOP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S137.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SPOP MUTATED 1 4 4 2 2 3 1
SPOP WILD-TYPE 23 46 27 17 20 30 23
'SPOP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.424 (Fisher's exact test), Q value = 0.76

Table S138.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SPOP MUTATED 3 8 4 2
SPOP WILD-TYPE 65 70 27 24
'SPOP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 0.69

Table S139.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SPOP MUTATED 4 8 5 4
SPOP WILD-TYPE 60 65 31 70
'SPOP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.11 (Fisher's exact test), Q value = 0.39

Table S140.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SPOP MUTATED 2 1 2 4 7 1 4
SPOP WILD-TYPE 42 40 15 29 28 30 42
'SPOP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.46

Table S141.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SPOP MUTATED 2 3 11 4 1
SPOP WILD-TYPE 39 37 53 71 19
'SPOP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.613 (Fisher's exact test), Q value = 0.91

Table S142.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SPOP MUTATED 11 5 5
SPOP WILD-TYPE 93 50 76
'SPOP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 0.67

Table S143.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SPOP MUTATED 0 2 2 4
SPOP WILD-TYPE 14 45 19 26
'SPOP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 0.7

Table S144.  Gene #12: 'SPOP MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SPOP MUTATED 4 2 2
SPOP WILD-TYPE 30 51 23
'FGFR2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.641 (Fisher's exact test), Q value = 0.94

Table S145.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
FGFR2 MUTATED 3 2 1 0
FGFR2 WILD-TYPE 10 16 12 7
'FGFR2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 0.71

Table S146.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
FGFR2 MUTATED 2 0 1 2 1
FGFR2 WILD-TYPE 10 10 6 5 14
'FGFR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0549 (Fisher's exact test), Q value = 0.28

Table S147.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FGFR2 MUTATED 4 17 5 4
FGFR2 WILD-TYPE 67 70 49 26
'FGFR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S148.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
FGFR2 MUTATED 5 3 9
FGFR2 WILD-TYPE 39 25 54
'FGFR2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.992 (Fisher's exact test), Q value = 1

Table S149.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FGFR2 MUTATED 2 7 5 2 3 5 3
FGFR2 WILD-TYPE 22 43 26 17 19 28 21
'FGFR2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 0.98

Table S150.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FGFR2 MUTATED 11 8 4 4
FGFR2 WILD-TYPE 57 70 27 22
'FGFR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S151.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FGFR2 MUTATED 6 10 6 9
FGFR2 WILD-TYPE 58 63 30 65
'FGFR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0759 (Fisher's exact test), Q value = 0.33

Table S152.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FGFR2 MUTATED 2 2 2 8 7 3 7
FGFR2 WILD-TYPE 42 39 15 25 28 28 39
'FGFR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 0.85

Table S153.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FGFR2 MUTATED 4 3 12 9 2
FGFR2 WILD-TYPE 37 37 52 66 18
'FGFR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.415 (Fisher's exact test), Q value = 0.76

Table S154.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FGFR2 MUTATED 15 4 11
FGFR2 WILD-TYPE 89 51 70
'FGFR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.712 (Fisher's exact test), Q value = 0.98

Table S155.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
FGFR2 MUTATED 3 5 3 4
FGFR2 WILD-TYPE 11 42 18 26
'FGFR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S156.  Gene #13: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
FGFR2 MUTATED 4 7 4
FGFR2 WILD-TYPE 30 46 21
'TCP11L2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 0.38

Table S157.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
TCP11L2 MUTATED 4 2 0 0
TCP11L2 WILD-TYPE 9 16 13 7
'TCP11L2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0184 (Fisher's exact test), Q value = 0.15

Table S158.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
TCP11L2 MUTATED 2 0 1 3 0
TCP11L2 WILD-TYPE 10 10 6 4 15

Figure S74.  Get High-res Image Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TCP11L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00391 (Fisher's exact test), Q value = 0.053

Table S159.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TCP11L2 MUTATED 0 11 2 1
TCP11L2 WILD-TYPE 71 76 52 29

Figure S75.  Get High-res Image Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TCP11L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.298 (Fisher's exact test), Q value = 0.64

Table S160.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TCP11L2 MUTATED 1 0 5
TCP11L2 WILD-TYPE 43 28 58
'TCP11L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.712 (Fisher's exact test), Q value = 0.98

Table S161.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TCP11L2 MUTATED 2 3 2 2 2 1 0
TCP11L2 WILD-TYPE 22 47 29 17 20 32 24
'TCP11L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.648 (Fisher's exact test), Q value = 0.94

Table S162.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TCP11L2 MUTATED 4 6 2 0
TCP11L2 WILD-TYPE 64 72 29 26
'TCP11L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 0.5

Table S163.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TCP11L2 MUTATED 2 6 4 2
TCP11L2 WILD-TYPE 62 67 32 72
'TCP11L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 7e-05 (Fisher's exact test), Q value = 0.0037

Table S164.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TCP11L2 MUTATED 0 0 1 6 6 0 1
TCP11L2 WILD-TYPE 44 41 16 27 29 31 45

Figure S76.  Get High-res Image Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TCP11L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00173 (Fisher's exact test), Q value = 0.032

Table S165.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TCP11L2 MUTATED 1 0 10 1 1
TCP11L2 WILD-TYPE 40 40 54 74 19

Figure S77.  Get High-res Image Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'TCP11L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.498 (Fisher's exact test), Q value = 0.83

Table S166.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TCP11L2 MUTATED 8 2 3
TCP11L2 WILD-TYPE 96 53 78
'TCP11L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 0.95

Table S167.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
TCP11L2 MUTATED 0 1 1 2
TCP11L2 WILD-TYPE 14 46 20 28
'TCP11L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 0.52

Table S168.  Gene #14: 'TCP11L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
TCP11L2 MUTATED 3 1 0
TCP11L2 WILD-TYPE 31 52 25
'VPS11 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 0.83

Table S169.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
VPS11 MUTATED 2 1 0 0
VPS11 WILD-TYPE 11 17 13 7
'VPS11 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.63

Table S170.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
VPS11 MUTATED 1 0 1 1 0
VPS11 WILD-TYPE 11 10 6 6 15
'VPS11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 0.75

Table S171.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
VPS11 MUTATED 1 5 3 2
VPS11 WILD-TYPE 70 82 51 28
'VPS11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S172.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
VPS11 MUTATED 2 0 2
VPS11 WILD-TYPE 42 28 61
'VPS11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S173.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
VPS11 MUTATED 1 2 2 0 1 3 0
VPS11 WILD-TYPE 23 48 29 19 21 30 24
'VPS11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.388 (Fisher's exact test), Q value = 0.73

Table S174.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
VPS11 MUTATED 3 3 3 0
VPS11 WILD-TYPE 65 75 28 26
'VPS11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0157 (Fisher's exact test), Q value = 0.14

Table S175.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
VPS11 MUTATED 2 5 4 0
VPS11 WILD-TYPE 62 68 32 74

Figure S78.  Get High-res Image Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'VPS11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0132 (Fisher's exact test), Q value = 0.12

Table S176.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
VPS11 MUTATED 1 0 1 3 5 1 0
VPS11 WILD-TYPE 43 41 16 30 30 30 46

Figure S79.  Get High-res Image Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'VPS11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0121 (Fisher's exact test), Q value = 0.12

Table S177.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
VPS11 MUTATED 2 0 8 1 0
VPS11 WILD-TYPE 39 40 56 74 20

Figure S80.  Get High-res Image Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'VPS11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 0.85

Table S178.  Gene #15: 'VPS11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
VPS11 MUTATED 6 3 2
VPS11 WILD-TYPE 98 52 79
'PPP2R1A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 0.41

Table S179.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PPP2R1A MUTATED 3 5 0 0
PPP2R1A WILD-TYPE 10 13 13 7
'PPP2R1A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0554 (Fisher's exact test), Q value = 0.28

Table S180.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PPP2R1A MUTATED 4 2 0 2 0
PPP2R1A WILD-TYPE 8 8 7 5 15
'PPP2R1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 0.41

Table S181.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PPP2R1A MUTATED 13 8 3 2
PPP2R1A WILD-TYPE 58 79 51 28
'PPP2R1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 0.39

Table S182.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PPP2R1A MUTATED 9 2 5
PPP2R1A WILD-TYPE 35 26 58
'PPP2R1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.44

Table S183.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PPP2R1A MUTATED 1 4 5 4 5 1 3
PPP2R1A WILD-TYPE 23 46 26 15 17 32 21
'PPP2R1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0645 (Fisher's exact test), Q value = 0.31

Table S184.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PPP2R1A MUTATED 5 15 2 1
PPP2R1A WILD-TYPE 63 63 29 25
'PPP2R1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00713 (Fisher's exact test), Q value = 0.078

Table S185.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PPP2R1A MUTATED 15 7 2 4
PPP2R1A WILD-TYPE 49 66 34 70

Figure S81.  Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PPP2R1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0233 (Fisher's exact test), Q value = 0.17

Table S186.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PPP2R1A MUTATED 12 3 2 4 4 1 2
PPP2R1A WILD-TYPE 32 38 15 29 31 30 44

Figure S82.  Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PPP2R1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0731 (Fisher's exact test), Q value = 0.33

Table S187.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PPP2R1A MUTATED 10 3 6 5 2
PPP2R1A WILD-TYPE 31 37 58 70 18
'PPP2R1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00472 (Fisher's exact test), Q value = 0.061

Table S188.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PPP2R1A MUTATED 8 13 5
PPP2R1A WILD-TYPE 96 42 76

Figure S83.  Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PPP2R1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0024 (Fisher's exact test), Q value = 0.039

Table S189.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PPP2R1A MUTATED 7 4 3 2
PPP2R1A WILD-TYPE 7 43 18 28

Figure S84.  Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PPP2R1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0228 (Fisher's exact test), Q value = 0.17

Table S190.  Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PPP2R1A MUTATED 9 3 4
PPP2R1A WILD-TYPE 25 50 21

Figure S85.  Get High-res Image Gene #16: 'PPP2R1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MAX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0679 (Fisher's exact test), Q value = 0.31

Table S191.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MAX MUTATED 0 3 4 2
MAX WILD-TYPE 71 84 50 28
'MAX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S192.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MAX MUTATED 2 1 3
MAX WILD-TYPE 42 27 60
'MAX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S193.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MAX MUTATED 0 3 2 0 1 2 0
MAX WILD-TYPE 24 47 29 19 21 31 24
'MAX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.718 (Fisher's exact test), Q value = 0.99

Table S194.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MAX MUTATED 3 3 2 0
MAX WILD-TYPE 65 75 29 26
'MAX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.121 (Fisher's exact test), Q value = 0.41

Table S195.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MAX MUTATED 0 5 2 2
MAX WILD-TYPE 64 68 34 72
'MAX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.63

Table S196.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MAX MUTATED 0 1 1 2 3 0 2
MAX WILD-TYPE 44 40 16 31 32 31 44
'MAX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.971 (Fisher's exact test), Q value = 1

Table S197.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MAX MUTATED 1 2 3 3 0
MAX WILD-TYPE 40 38 61 72 20
'MAX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 0.98

Table S198.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MAX MUTATED 4 1 4
MAX WILD-TYPE 100 54 77
'MAX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S199.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MAX MUTATED 0 2 1 1
MAX WILD-TYPE 14 45 20 29
'MAX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.686 (Fisher's exact test), Q value = 0.97

Table S200.  Gene #17: 'MAX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MAX MUTATED 2 2 0
MAX WILD-TYPE 32 51 25
'SOX17 MUTATION STATUS' versus 'CN_CNMF'

P value = 3e-04 (Fisher's exact test), Q value = 0.01

Table S201.  Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SOX17 MUTATED 0 1 1 5
SOX17 WILD-TYPE 71 86 53 25

Figure S86.  Get High-res Image Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SOX17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0381 (Fisher's exact test), Q value = 0.23

Table S202.  Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SOX17 MUTATED 0 3 1
SOX17 WILD-TYPE 44 25 62

Figure S87.  Get High-res Image Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'SOX17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 0.69

Table S203.  Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SOX17 MUTATED 0 4 0 1 0 1 0
SOX17 WILD-TYPE 24 46 31 18 22 32 24
'SOX17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S204.  Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SOX17 MUTATED 2 2 1 1
SOX17 WILD-TYPE 66 76 30 25
'SOX17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 0.75

Table S205.  Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SOX17 MUTATED 2 1 0 4
SOX17 WILD-TYPE 62 72 36 70
'SOX17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.486 (Fisher's exact test), Q value = 0.82

Table S206.  Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SOX17 MUTATED 1 0 0 0 2 1 3
SOX17 WILD-TYPE 43 41 17 33 33 30 43
'SOX17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0914 (Fisher's exact test), Q value = 0.36

Table S207.  Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SOX17 MUTATED 0 1 0 5 1
SOX17 WILD-TYPE 41 39 64 70 19
'SOX17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.548 (Fisher's exact test), Q value = 0.86

Table S208.  Gene #18: 'SOX17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SOX17 MUTATED 2 1 4
SOX17 WILD-TYPE 102 54 77
'CCND1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 0.72

Table S209.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CCND1 MUTATED 2 1 0 1
CCND1 WILD-TYPE 11 17 13 6
'CCND1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.811 (Fisher's exact test), Q value = 1

Table S210.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CCND1 MUTATED 1 0 1 1 1
CCND1 WILD-TYPE 11 10 6 6 14
'CCND1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00196 (Fisher's exact test), Q value = 0.035

Table S211.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CCND1 MUTATED 0 11 3 0
CCND1 WILD-TYPE 71 76 51 30

Figure S88.  Get High-res Image Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CCND1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 0.85

Table S212.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CCND1 MUTATED 1 1 5
CCND1 WILD-TYPE 43 27 58
'CCND1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S213.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CCND1 MUTATED 2 2 1 2 1 1 1
CCND1 WILD-TYPE 22 48 30 17 21 32 23
'CCND1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S214.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CCND1 MUTATED 2 5 2 1
CCND1 WILD-TYPE 66 73 29 25
'CCND1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 0.93

Table S215.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CCND1 MUTATED 2 6 2 4
CCND1 WILD-TYPE 62 67 34 70
'CCND1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0484 (Fisher's exact test), Q value = 0.26

Table S216.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CCND1 MUTATED 0 1 0 5 4 1 3
CCND1 WILD-TYPE 44 40 17 28 31 30 43

Figure S89.  Get High-res Image Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCND1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.4

Table S217.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CCND1 MUTATED 0 2 7 3 2
CCND1 WILD-TYPE 41 38 57 72 18
'CCND1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0923 (Fisher's exact test), Q value = 0.36

Table S218.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CCND1 MUTATED 8 0 6
CCND1 WILD-TYPE 96 55 75
'CCND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.527 (Fisher's exact test), Q value = 0.85

Table S219.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CCND1 MUTATED 0 3 1 0
CCND1 WILD-TYPE 14 44 20 30
'CCND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 0.78

Table S220.  Gene #19: 'CCND1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CCND1 MUTATED 0 3 1
CCND1 WILD-TYPE 34 50 24
'NRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.61

Table S221.  Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NRAS MUTATED 1 6 2 0
NRAS WILD-TYPE 70 81 52 30
'NRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.554 (Fisher's exact test), Q value = 0.87

Table S222.  Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NRAS MUTATED 0 2 0 0 2 1 1
NRAS WILD-TYPE 24 48 31 19 20 32 23
'NRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0484 (Fisher's exact test), Q value = 0.26

Table S223.  Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NRAS MUTATED 2 0 2 2
NRAS WILD-TYPE 66 78 29 24

Figure S90.  Get High-res Image Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'NRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 0.89

Table S224.  Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NRAS MUTATED 3 4 0 2
NRAS WILD-TYPE 61 69 36 72
'NRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S225.  Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NRAS MUTATED 1 2 1 1 2 0 2
NRAS WILD-TYPE 43 39 16 32 33 31 44
'NRAS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S226.  Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NRAS MUTATED 1 1 4 3 0
NRAS WILD-TYPE 40 39 60 72 20
'NRAS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S227.  Gene #20: 'NRAS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NRAS MUTATED 5 1 3
NRAS WILD-TYPE 99 54 78
'EP300 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S228.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
EP300 MUTATED 1 1 1 0
EP300 WILD-TYPE 12 17 12 7
'EP300 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S229.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
EP300 MUTATED 1 0 1 0 1
EP300 WILD-TYPE 11 10 6 7 14
'EP300 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00175 (Fisher's exact test), Q value = 0.032

Table S230.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
EP300 MUTATED 0 13 6 2
EP300 WILD-TYPE 71 74 48 28

Figure S91.  Get High-res Image Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'EP300 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.395 (Fisher's exact test), Q value = 0.74

Table S231.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
EP300 MUTATED 1 2 6
EP300 WILD-TYPE 43 26 57
'EP300 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0351 (Fisher's exact test), Q value = 0.22

Table S232.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
EP300 MUTATED 3 2 8 2 2 3 0
EP300 WILD-TYPE 21 48 23 17 20 30 24

Figure S92.  Get High-res Image Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'EP300 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 0.4

Table S233.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
EP300 MUTATED 9 6 5 0
EP300 WILD-TYPE 59 72 26 26
'EP300 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 0.69

Table S234.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
EP300 MUTATED 2 7 4 7
EP300 WILD-TYPE 62 66 32 67
'EP300 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.032 (Fisher's exact test), Q value = 0.21

Table S235.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
EP300 MUTATED 0 2 2 6 5 1 4
EP300 WILD-TYPE 44 39 15 27 30 30 42

Figure S93.  Get High-res Image Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'EP300 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0942 (Fisher's exact test), Q value = 0.36

Table S236.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
EP300 MUTATED 1 2 11 6 1
EP300 WILD-TYPE 40 38 53 69 19
'EP300 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 0.65

Table S237.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
EP300 MUTATED 10 2 9
EP300 WILD-TYPE 94 53 72
'EP300 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S238.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
EP300 MUTATED 0 3 1 2
EP300 WILD-TYPE 14 44 20 28
'EP300 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.157 (Fisher's exact test), Q value = 0.47

Table S239.  Gene #21: 'EP300 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
EP300 MUTATED 2 1 3
EP300 WILD-TYPE 32 52 22
'KLHL8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S240.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
KLHL8 MUTATED 2 1 0 0
KLHL8 WILD-TYPE 11 17 13 7
'KLHL8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.63

Table S241.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
KLHL8 MUTATED 1 0 1 1 0
KLHL8 WILD-TYPE 11 10 6 6 15
'KLHL8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0275 (Fisher's exact test), Q value = 0.19

Table S242.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
KLHL8 MUTATED 0 8 2 2
KLHL8 WILD-TYPE 71 79 52 28

Figure S94.  Get High-res Image Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'KLHL8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.64

Table S243.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
KLHL8 MUTATED 1 0 5
KLHL8 WILD-TYPE 43 28 58
'KLHL8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.99 (Fisher's exact test), Q value = 1

Table S244.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
KLHL8 MUTATED 1 4 1 1 1 1 1
KLHL8 WILD-TYPE 23 46 30 18 21 32 23
'KLHL8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.964 (Fisher's exact test), Q value = 1

Table S245.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
KLHL8 MUTATED 3 4 2 1
KLHL8 WILD-TYPE 65 74 29 25
'KLHL8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.151 (Fisher's exact test), Q value = 0.47

Table S246.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
KLHL8 MUTATED 1 6 3 2
KLHL8 WILD-TYPE 63 67 33 72
'KLHL8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00482 (Fisher's exact test), Q value = 0.062

Table S247.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
KLHL8 MUTATED 0 1 1 6 3 0 1
KLHL8 WILD-TYPE 44 40 16 27 32 31 45

Figure S95.  Get High-res Image Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'KLHL8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 0.41

Table S248.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
KLHL8 MUTATED 0 2 7 3 0
KLHL8 WILD-TYPE 41 38 57 72 20
'KLHL8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.693 (Fisher's exact test), Q value = 0.97

Table S249.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
KLHL8 MUTATED 7 2 3
KLHL8 WILD-TYPE 97 53 78
'KLHL8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.53 (Fisher's exact test), Q value = 0.85

Table S250.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
KLHL8 MUTATED 0 4 0 1
KLHL8 WILD-TYPE 14 43 21 29
'KLHL8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 0.7

Table S251.  Gene #22: 'KLHL8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
KLHL8 MUTATED 3 2 0
KLHL8 WILD-TYPE 31 51 25
'ALG8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S252.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ALG8 MUTATED 1 1 1 0
ALG8 WILD-TYPE 12 17 12 7
'ALG8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.53

Table S253.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ALG8 MUTATED 2 0 1 0 0
ALG8 WILD-TYPE 10 10 6 7 15
'ALG8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 0.47

Table S254.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ALG8 MUTATED 1 7 3 0
ALG8 WILD-TYPE 70 80 51 30
'ALG8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 0.83

Table S255.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ALG8 MUTATED 1 0 4
ALG8 WILD-TYPE 43 28 59
'ALG8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0379 (Fisher's exact test), Q value = 0.23

Table S256.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ALG8 MUTATED 0 2 4 3 0 0 2
ALG8 WILD-TYPE 24 48 27 16 22 33 22

Figure S96.  Get High-res Image Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'ALG8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.74

Table S257.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ALG8 MUTATED 3 6 0 2
ALG8 WILD-TYPE 65 72 31 24
'ALG8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S258.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ALG8 MUTATED 2 4 2 3
ALG8 WILD-TYPE 62 69 34 71
'ALG8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 0.5

Table S259.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ALG8 MUTATED 0 1 1 4 2 2 1
ALG8 WILD-TYPE 44 40 16 29 33 29 45
'ALG8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 0.75

Table S260.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ALG8 MUTATED 1 0 5 4 1
ALG8 WILD-TYPE 40 40 59 71 19
'ALG8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0692 (Fisher's exact test), Q value = 0.32

Table S261.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ALG8 MUTATED 8 0 3
ALG8 WILD-TYPE 96 55 78
'ALG8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.54

Table S262.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ALG8 MUTATED 0 0 1 2
ALG8 WILD-TYPE 14 47 20 28
'ALG8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S263.  Gene #23: 'ALG8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ALG8 MUTATED 1 1 1
ALG8 WILD-TYPE 33 52 24
'GNPTAB MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 0.79

Table S264.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
GNPTAB MUTATED 1 3 0 0
GNPTAB WILD-TYPE 12 15 13 7
'GNPTAB MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0778 (Fisher's exact test), Q value = 0.33

Table S265.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
GNPTAB MUTATED 3 0 1 0 0
GNPTAB WILD-TYPE 9 10 6 7 15
'GNPTAB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00972 (Fisher's exact test), Q value = 0.099

Table S266.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
GNPTAB MUTATED 1 13 5 1
GNPTAB WILD-TYPE 70 74 49 29

Figure S97.  Get High-res Image Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'GNPTAB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.387 (Fisher's exact test), Q value = 0.73

Table S267.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
GNPTAB MUTATED 3 1 8
GNPTAB WILD-TYPE 41 27 55
'GNPTAB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.64

Table S268.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
GNPTAB MUTATED 2 2 4 4 3 2 1
GNPTAB WILD-TYPE 22 48 27 15 19 31 23
'GNPTAB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.633 (Fisher's exact test), Q value = 0.93

Table S269.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
GNPTAB MUTATED 5 8 4 1
GNPTAB WILD-TYPE 63 70 27 25
'GNPTAB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 0.5

Table S270.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
GNPTAB MUTATED 5 6 6 3
GNPTAB WILD-TYPE 59 67 30 71
'GNPTAB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00043 (Fisher's exact test), Q value = 0.013

Table S271.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
GNPTAB MUTATED 1 1 1 7 8 1 1
GNPTAB WILD-TYPE 43 40 16 26 27 30 45

Figure S98.  Get High-res Image Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'GNPTAB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.156 (Fisher's exact test), Q value = 0.47

Table S272.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
GNPTAB MUTATED 2 1 10 5 1
GNPTAB WILD-TYPE 39 39 54 70 19
'GNPTAB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0765 (Fisher's exact test), Q value = 0.33

Table S273.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
GNPTAB MUTATED 13 3 3
GNPTAB WILD-TYPE 91 52 78
'GNPTAB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0698 (Fisher's exact test), Q value = 0.32

Table S274.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
GNPTAB MUTATED 0 2 1 6
GNPTAB WILD-TYPE 14 45 20 24
'GNPTAB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.63

Table S275.  Gene #24: 'GNPTAB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
GNPTAB MUTATED 4 2 3
GNPTAB WILD-TYPE 30 51 22
'SIN3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0122 (Fisher's exact test), Q value = 0.12

Table S276.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SIN3A MUTATED 2 13 5 0
SIN3A WILD-TYPE 69 74 49 30

Figure S99.  Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SIN3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.357 (Fisher's exact test), Q value = 0.7

Table S277.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SIN3A MUTATED 4 1 9
SIN3A WILD-TYPE 40 27 54
'SIN3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0693 (Fisher's exact test), Q value = 0.32

Table S278.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SIN3A MUTATED 3 2 8 1 2 2 1
SIN3A WILD-TYPE 21 48 23 18 20 31 23
'SIN3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0778 (Fisher's exact test), Q value = 0.33

Table S279.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SIN3A MUTATED 4 6 7 2
SIN3A WILD-TYPE 64 72 24 24
'SIN3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00223 (Fisher's exact test), Q value = 0.038

Table S280.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SIN3A MUTATED 3 12 5 1
SIN3A WILD-TYPE 61 61 31 73

Figure S100.  Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SIN3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00024 (Fisher's exact test), Q value = 0.0083

Table S281.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SIN3A MUTATED 0 3 1 5 10 1 1
SIN3A WILD-TYPE 44 38 16 28 25 30 45

Figure S101.  Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SIN3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0467 (Fisher's exact test), Q value = 0.26

Table S282.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SIN3A MUTATED 2 5 10 2 2
SIN3A WILD-TYPE 39 35 54 73 18

Figure S102.  Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'SIN3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00524 (Fisher's exact test), Q value = 0.064

Table S283.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SIN3A MUTATED 16 3 2
SIN3A WILD-TYPE 88 52 79

Figure S103.  Get High-res Image Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'SIN3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S284.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SIN3A MUTATED 0 2 2 5
SIN3A WILD-TYPE 14 45 19 25
'SIN3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.287 (Fisher's exact test), Q value = 0.63

Table S285.  Gene #25: 'SIN3A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SIN3A MUTATED 4 2 3
SIN3A WILD-TYPE 30 51 22
'ARID5B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S286.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ARID5B MUTATED 3 3 3 1
ARID5B WILD-TYPE 10 15 10 6
'ARID5B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 0.45

Table S287.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ARID5B MUTATED 4 0 3 1 2
ARID5B WILD-TYPE 8 10 4 6 13
'ARID5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00362 (Fisher's exact test), Q value = 0.051

Table S288.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ARID5B MUTATED 1 15 8 4
ARID5B WILD-TYPE 70 72 46 26

Figure S104.  Get High-res Image Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ARID5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.54

Table S289.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ARID5B MUTATED 2 0 6
ARID5B WILD-TYPE 42 28 57
'ARID5B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 0.82

Table S290.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ARID5B MUTATED 2 6 5 5 2 2 2
ARID5B WILD-TYPE 22 44 26 14 20 31 22
'ARID5B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S291.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ARID5B MUTATED 9 8 3 4
ARID5B WILD-TYPE 59 70 28 22
'ARID5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0969 (Fisher's exact test), Q value = 0.36

Table S292.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ARID5B MUTATED 3 8 7 11
ARID5B WILD-TYPE 61 65 29 63
'ARID5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0428 (Fisher's exact test), Q value = 0.25

Table S293.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ARID5B MUTATED 1 2 1 7 7 5 6
ARID5B WILD-TYPE 43 39 16 26 28 26 40

Figure S105.  Get High-res Image Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ARID5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0627 (Fisher's exact test), Q value = 0.3

Table S294.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ARID5B MUTATED 1 2 12 10 2
ARID5B WILD-TYPE 40 38 52 65 18
'ARID5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 0.66

Table S295.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ARID5B MUTATED 14 3 10
ARID5B WILD-TYPE 90 52 71
'ARID5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 0.91

Table S296.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ARID5B MUTATED 0 2 1 3
ARID5B WILD-TYPE 14 45 20 27
'ARID5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S297.  Gene #26: 'ARID5B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ARID5B MUTATED 1 4 1
ARID5B WILD-TYPE 33 49 24
'NFE2L2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S298.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
NFE2L2 MUTATED 0 1 3 0
NFE2L2 WILD-TYPE 13 17 10 7
'NFE2L2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.323 (Fisher's exact test), Q value = 0.66

Table S299.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
NFE2L2 MUTATED 1 0 2 0 1
NFE2L2 WILD-TYPE 11 10 5 7 14
'NFE2L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S300.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NFE2L2 MUTATED 3 5 4 2
NFE2L2 WILD-TYPE 68 82 50 28
'NFE2L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S301.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
NFE2L2 MUTATED 1 1 4
NFE2L2 WILD-TYPE 43 27 59
'NFE2L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.61

Table S302.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NFE2L2 MUTATED 4 1 2 0 1 2 2
NFE2L2 WILD-TYPE 20 49 29 19 21 31 22
'NFE2L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0554 (Fisher's exact test), Q value = 0.28

Table S303.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NFE2L2 MUTATED 7 1 3 1
NFE2L2 WILD-TYPE 61 77 28 25
'NFE2L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0115 (Fisher's exact test), Q value = 0.11

Table S304.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NFE2L2 MUTATED 1 1 4 8
NFE2L2 WILD-TYPE 63 72 32 66

Figure S106.  Get High-res Image Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'NFE2L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.019 (Fisher's exact test), Q value = 0.15

Table S305.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NFE2L2 MUTATED 0 0 2 2 1 3 6
NFE2L2 WILD-TYPE 44 41 15 31 34 28 40

Figure S107.  Get High-res Image Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NFE2L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 0.39

Table S306.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NFE2L2 MUTATED 0 1 6 7 0
NFE2L2 WILD-TYPE 41 39 58 68 20
'NFE2L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0693 (Fisher's exact test), Q value = 0.32

Table S307.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NFE2L2 MUTATED 3 2 9
NFE2L2 WILD-TYPE 101 53 72
'NFE2L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.43

Table S308.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
NFE2L2 MUTATED 0 5 0 0
NFE2L2 WILD-TYPE 14 42 21 30
'NFE2L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S309.  Gene #27: 'NFE2L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
NFE2L2 MUTATED 1 4 0
NFE2L2 WILD-TYPE 33 49 25
'ZNF471 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S310.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZNF471 MUTATED 2 1 1 0
ZNF471 WILD-TYPE 11 17 12 7
'ZNF471 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0927 (Fisher's exact test), Q value = 0.36

Table S311.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZNF471 MUTATED 1 0 2 1 0
ZNF471 WILD-TYPE 11 10 5 6 15
'ZNF471 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00455 (Fisher's exact test), Q value = 0.06

Table S312.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF471 MUTATED 0 11 2 2
ZNF471 WILD-TYPE 71 76 52 28

Figure S108.  Get High-res Image Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF471 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 0.85

Table S313.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF471 MUTATED 1 1 5
ZNF471 WILD-TYPE 43 27 58
'ZNF471 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 0.94

Table S314.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF471 MUTATED 2 1 3 2 2 2 1
ZNF471 WILD-TYPE 22 49 28 17 20 31 23
'ZNF471 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 0.78

Table S315.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF471 MUTATED 3 5 4 1
ZNF471 WILD-TYPE 65 73 27 25
'ZNF471 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 0.83

Table S316.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF471 MUTATED 3 5 4 3
ZNF471 WILD-TYPE 61 68 32 71
'ZNF471 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 8e-05 (Fisher's exact test), Q value = 0.0039

Table S317.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF471 MUTATED 0 0 0 6 7 1 1
ZNF471 WILD-TYPE 44 41 17 27 28 30 45

Figure S109.  Get High-res Image Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF471 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0475 (Fisher's exact test), Q value = 0.26

Table S318.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF471 MUTATED 0 3 8 2 1
ZNF471 WILD-TYPE 41 37 56 73 19

Figure S110.  Get High-res Image Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ZNF471 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0259 (Fisher's exact test), Q value = 0.19

Table S319.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF471 MUTATED 11 1 2
ZNF471 WILD-TYPE 93 54 79

Figure S111.  Get High-res Image Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ZNF471 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S320.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF471 MUTATED 0 3 1 1
ZNF471 WILD-TYPE 14 44 20 29
'ZNF471 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S321.  Gene #28: 'ZNF471 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF471 MUTATED 2 2 1
ZNF471 WILD-TYPE 32 51 24
'MORC4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 0.7

Table S322.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MORC4 MUTATED 2 3 0 0
MORC4 WILD-TYPE 11 15 13 7
'MORC4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S323.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MORC4 MUTATED 2 1 1 0 1
MORC4 WILD-TYPE 10 9 6 7 14
'MORC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00656 (Fisher's exact test), Q value = 0.075

Table S324.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MORC4 MUTATED 2 14 4 0
MORC4 WILD-TYPE 69 73 50 30

Figure S112.  Get High-res Image Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MORC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 0.66

Table S325.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MORC4 MUTATED 2 2 8
MORC4 WILD-TYPE 42 26 55
'MORC4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 0.65

Table S326.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MORC4 MUTATED 1 4 6 1 2 3 0
MORC4 WILD-TYPE 23 46 25 18 20 30 24
'MORC4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0576 (Fisher's exact test), Q value = 0.29

Table S327.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MORC4 MUTATED 4 7 6 0
MORC4 WILD-TYPE 64 71 25 26
'MORC4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00702 (Fisher's exact test), Q value = 0.078

Table S328.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MORC4 MUTATED 2 10 6 2
MORC4 WILD-TYPE 62 63 30 72

Figure S113.  Get High-res Image Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MORC4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0827 (Fisher's exact test), Q value = 0.34

Table S329.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MORC4 MUTATED 1 4 1 6 5 2 1
MORC4 WILD-TYPE 43 37 16 27 30 29 45
'MORC4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.244 (Fisher's exact test), Q value = 0.59

Table S330.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MORC4 MUTATED 2 3 9 3 2
MORC4 WILD-TYPE 39 37 55 72 18
'MORC4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0312 (Fisher's exact test), Q value = 0.21

Table S331.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MORC4 MUTATED 14 2 3
MORC4 WILD-TYPE 90 53 78

Figure S114.  Get High-res Image Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MORC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 0.82

Table S332.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MORC4 MUTATED 0 3 3 3
MORC4 WILD-TYPE 14 44 18 27
'MORC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 0.52

Table S333.  Gene #29: 'MORC4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MORC4 MUTATED 1 4 4
MORC4 WILD-TYPE 33 49 21
'SELP MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S334.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
SELP MUTATED 2 1 0 0
SELP WILD-TYPE 11 17 13 7
'SELP MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S335.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
SELP MUTATED 1 0 1 1 0
SELP WILD-TYPE 11 10 6 6 15
'SELP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 0.47

Table S336.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SELP MUTATED 1 7 1 1
SELP WILD-TYPE 70 80 53 29
'SELP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S337.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SELP MUTATED 1 1 1
SELP WILD-TYPE 43 27 62
'SELP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S338.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SELP MUTATED 0 1 2 1 1 2 1
SELP WILD-TYPE 24 49 29 18 21 31 23
'SELP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 0.84

Table S339.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SELP MUTATED 1 4 2 1
SELP WILD-TYPE 67 74 29 25
'SELP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0176 (Fisher's exact test), Q value = 0.14

Table S340.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SELP MUTATED 1 3 5 1
SELP WILD-TYPE 63 70 31 73

Figure S115.  Get High-res Image Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SELP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00664 (Fisher's exact test), Q value = 0.075

Table S341.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SELP MUTATED 0 0 2 3 4 0 1
SELP WILD-TYPE 44 41 15 30 31 31 45

Figure S116.  Get High-res Image Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SELP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.025 (Fisher's exact test), Q value = 0.18

Table S342.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SELP MUTATED 0 1 7 1 0
SELP WILD-TYPE 41 39 57 74 20

Figure S117.  Get High-res Image Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'SELP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 0.65

Table S343.  Gene #30: 'SELP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SELP MUTATED 5 3 1
SELP WILD-TYPE 99 52 80
'RBMX MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.65

Table S344.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
RBMX MUTATED 3 2 0 0
RBMX WILD-TYPE 10 16 13 7
'RBMX MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0916 (Fisher's exact test), Q value = 0.36

Table S345.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
RBMX MUTATED 2 0 1 2 0
RBMX WILD-TYPE 10 10 6 5 15
'RBMX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0323 (Fisher's exact test), Q value = 0.21

Table S346.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RBMX MUTATED 0 8 2 1
RBMX WILD-TYPE 71 79 52 29

Figure S118.  Get High-res Image Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RBMX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S347.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RBMX MUTATED 1 0 2
RBMX WILD-TYPE 43 28 61
'RBMX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 0.77

Table S348.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RBMX MUTATED 3 2 1 2 1 1 0
RBMX WILD-TYPE 21 48 30 17 21 32 24
'RBMX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.751 (Fisher's exact test), Q value = 1

Table S349.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RBMX MUTATED 4 4 2 0
RBMX WILD-TYPE 64 74 29 26
'RBMX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.378 (Fisher's exact test), Q value = 0.72

Table S350.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RBMX MUTATED 2 3 4 3
RBMX WILD-TYPE 62 70 32 71
'RBMX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 0.39

Table S351.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RBMX MUTATED 1 0 1 5 2 1 2
RBMX WILD-TYPE 43 41 16 28 33 30 44
'RBMX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 0.59

Table S352.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RBMX MUTATED 1 1 7 3 0
RBMX WILD-TYPE 40 39 57 72 20
'RBMX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 0.97

Table S353.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RBMX MUTATED 7 2 3
RBMX WILD-TYPE 97 53 78
'RBMX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S354.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RBMX MUTATED 0 2 0 1
RBMX WILD-TYPE 14 45 21 29
'RBMX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 0.78

Table S355.  Gene #31: 'RBMX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RBMX MUTATED 2 1 0
RBMX WILD-TYPE 32 52 25
'FAT1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0122 (Fisher's exact test), Q value = 0.12

Table S356.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
FAT1 MUTATED 6 5 0 0
FAT1 WILD-TYPE 7 13 13 7

Figure S119.  Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'FAT1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00144 (Fisher's exact test), Q value = 0.029

Table S357.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
FAT1 MUTATED 4 1 1 5 0
FAT1 WILD-TYPE 8 9 6 2 15

Figure S120.  Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'FAT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.4

Table S358.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FAT1 MUTATED 7 21 8 4
FAT1 WILD-TYPE 64 66 46 26
'FAT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0322 (Fisher's exact test), Q value = 0.21

Table S359.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
FAT1 MUTATED 5 1 15
FAT1 WILD-TYPE 39 27 48

Figure S121.  Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'FAT1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.664 (Fisher's exact test), Q value = 0.95

Table S360.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FAT1 MUTATED 6 6 8 3 3 6 3
FAT1 WILD-TYPE 18 44 23 16 19 27 21
'FAT1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0704 (Fisher's exact test), Q value = 0.32

Table S361.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FAT1 MUTATED 13 9 10 3
FAT1 WILD-TYPE 55 69 21 23
'FAT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0654 (Fisher's exact test), Q value = 0.31

Table S362.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FAT1 MUTATED 7 13 11 9
FAT1 WILD-TYPE 57 60 25 65
'FAT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 8e-05 (Fisher's exact test), Q value = 0.0039

Table S363.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FAT1 MUTATED 2 2 2 13 11 5 5
FAT1 WILD-TYPE 42 39 15 20 24 26 41

Figure S122.  Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FAT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0148 (Fisher's exact test), Q value = 0.13

Table S364.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FAT1 MUTATED 4 2 18 10 4
FAT1 WILD-TYPE 37 38 46 65 16

Figure S123.  Get High-res Image Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'FAT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0709 (Fisher's exact test), Q value = 0.32

Table S365.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FAT1 MUTATED 22 4 12
FAT1 WILD-TYPE 82 51 69
'FAT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S366.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
FAT1 MUTATED 3 6 3 5
FAT1 WILD-TYPE 11 41 18 25
'FAT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.217 (Fisher's exact test), Q value = 0.55

Table S367.  Gene #32: 'FAT1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
FAT1 MUTATED 8 5 4
FAT1 WILD-TYPE 26 48 21
'MARK3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S368.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MARK3 MUTATED 3 1 0 0
MARK3 WILD-TYPE 10 17 13 7
'MARK3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0936 (Fisher's exact test), Q value = 0.36

Table S369.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MARK3 MUTATED 1 0 2 1 0
MARK3 WILD-TYPE 11 10 5 6 15
'MARK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0615 (Fisher's exact test), Q value = 0.3

Table S370.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MARK3 MUTATED 0 6 4 1
MARK3 WILD-TYPE 71 81 50 29
'MARK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 0.45

Table S371.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MARK3 MUTATED 0 0 4
MARK3 WILD-TYPE 44 28 59
'MARK3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0925 (Fisher's exact test), Q value = 0.36

Table S372.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MARK3 MUTATED 2 1 4 1 2 0 0
MARK3 WILD-TYPE 22 49 27 18 20 33 24
'MARK3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.304 (Fisher's exact test), Q value = 0.65

Table S373.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MARK3 MUTATED 2 5 3 0
MARK3 WILD-TYPE 66 73 28 26
'MARK3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0525 (Fisher's exact test), Q value = 0.27

Table S374.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MARK3 MUTATED 1 5 4 1
MARK3 WILD-TYPE 63 68 32 73
'MARK3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00051 (Fisher's exact test), Q value = 0.015

Table S375.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MARK3 MUTATED 0 0 0 3 6 2 0
MARK3 WILD-TYPE 44 41 17 30 29 29 46

Figure S124.  Get High-res Image Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MARK3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 0.51

Table S376.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MARK3 MUTATED 2 1 6 1 0
MARK3 WILD-TYPE 39 39 58 74 20
'MARK3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0107 (Fisher's exact test), Q value = 0.11

Table S377.  Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MARK3 MUTATED 9 0 1
MARK3 WILD-TYPE 95 55 80

Figure S125.  Get High-res Image Gene #33: 'MARK3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'SOS1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S378.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
SOS1 MUTATED 1 1 2 0
SOS1 WILD-TYPE 12 17 11 7
'SOS1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S379.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
SOS1 MUTATED 1 0 1 1 1
SOS1 WILD-TYPE 11 10 6 6 14
'SOS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0272 (Fisher's exact test), Q value = 0.19

Table S380.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SOS1 MUTATED 0 8 2 2
SOS1 WILD-TYPE 71 79 52 28

Figure S126.  Get High-res Image Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SOS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S381.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SOS1 MUTATED 2 0 2
SOS1 WILD-TYPE 42 28 61
'SOS1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 0.89

Table S382.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SOS1 MUTATED 1 2 3 0 2 1 0
SOS1 WILD-TYPE 23 48 28 19 20 32 24
'SOS1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.17 (Fisher's exact test), Q value = 0.49

Table S383.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SOS1 MUTATED 1 6 2 0
SOS1 WILD-TYPE 67 72 29 26
'SOS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 0.75

Table S384.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SOS1 MUTATED 1 4 3 3
SOS1 WILD-TYPE 63 69 33 71
'SOS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0389 (Fisher's exact test), Q value = 0.23

Table S385.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SOS1 MUTATED 0 0 1 2 4 3 1
SOS1 WILD-TYPE 44 41 16 31 31 28 45

Figure S127.  Get High-res Image Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SOS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 0.76

Table S386.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SOS1 MUTATED 0 2 5 3 1
SOS1 WILD-TYPE 41 38 59 72 19
'SOS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.669 (Fisher's exact test), Q value = 0.96

Table S387.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SOS1 MUTATED 6 1 4
SOS1 WILD-TYPE 98 54 77
'SOS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 0.89

Table S388.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SOS1 MUTATED 1 1 1 1
SOS1 WILD-TYPE 13 46 20 29
'SOS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0916 (Fisher's exact test), Q value = 0.36

Table S389.  Gene #34: 'SOS1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SOS1 MUTATED 2 0 2
SOS1 WILD-TYPE 32 53 23
'RBBP6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S390.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
RBBP6 MUTATED 1 3 1 0
RBBP6 WILD-TYPE 12 15 12 7
'RBBP6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.02 (Fisher's exact test), Q value = 0.15

Table S391.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
RBBP6 MUTATED 4 0 0 1 0
RBBP6 WILD-TYPE 8 10 7 6 15

Figure S128.  Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'RBBP6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00018 (Fisher's exact test), Q value = 0.0071

Table S392.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RBBP6 MUTATED 0 16 5 1
RBBP6 WILD-TYPE 71 71 49 29

Figure S129.  Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RBBP6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S393.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RBBP6 MUTATED 3 2 6
RBBP6 WILD-TYPE 41 26 57
'RBBP6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S394.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RBBP6 MUTATED 2 4 6 2 1 3 2
RBBP6 WILD-TYPE 22 46 25 17 21 30 22
'RBBP6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.727 (Fisher's exact test), Q value = 0.99

Table S395.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RBBP6 MUTATED 7 8 4 1
RBBP6 WILD-TYPE 61 70 27 25
'RBBP6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.109 (Fisher's exact test), Q value = 0.39

Table S396.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RBBP6 MUTATED 4 10 5 3
RBBP6 WILD-TYPE 60 63 31 71
'RBBP6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00011 (Fisher's exact test), Q value = 0.0048

Table S397.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RBBP6 MUTATED 0 2 1 7 9 2 1
RBBP6 WILD-TYPE 44 39 16 26 26 29 45

Figure S130.  Get High-res Image Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RBBP6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.095 (Fisher's exact test), Q value = 0.36

Table S398.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RBBP6 MUTATED 1 2 10 5 3
RBBP6 WILD-TYPE 40 38 54 70 17
'RBBP6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 0.37

Table S399.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RBBP6 MUTATED 14 3 4
RBBP6 WILD-TYPE 90 52 77
'RBBP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 0.82

Table S400.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RBBP6 MUTATED 0 3 3 3
RBBP6 WILD-TYPE 14 44 18 27
'RBBP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.348 (Fisher's exact test), Q value = 0.69

Table S401.  Gene #35: 'RBBP6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RBBP6 MUTATED 2 3 4
RBBP6 WILD-TYPE 32 50 21
'ZNF263 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0257 (Fisher's exact test), Q value = 0.18

Table S402.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF263 MUTATED 0 6 0 1
ZNF263 WILD-TYPE 71 81 54 29

Figure S131.  Get High-res Image Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF263 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S403.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF263 MUTATED 2 0 2
ZNF263 WILD-TYPE 42 28 61
'ZNF263 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0494 (Fisher's exact test), Q value = 0.26

Table S404.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF263 MUTATED 1 0 4 1 0 1 0
ZNF263 WILD-TYPE 23 50 27 18 22 32 24

Figure S132.  Get High-res Image Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'ZNF263 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S405.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF263 MUTATED 2 3 2 0
ZNF263 WILD-TYPE 66 75 29 26
'ZNF263 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.654 (Fisher's exact test), Q value = 0.95

Table S406.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF263 MUTATED 1 2 2 2
ZNF263 WILD-TYPE 63 71 34 72
'ZNF263 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.034 (Fisher's exact test), Q value = 0.22

Table S407.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF263 MUTATED 0 0 0 3 2 2 0
ZNF263 WILD-TYPE 44 41 17 30 33 29 46

Figure S133.  Get High-res Image Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF263 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 0.58

Table S408.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF263 MUTATED 0 1 1 3 2
ZNF263 WILD-TYPE 41 39 63 72 18
'ZNF263 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.386 (Fisher's exact test), Q value = 0.73

Table S409.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF263 MUTATED 4 0 3
ZNF263 WILD-TYPE 100 55 78
'ZNF263 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 0.81

Table S410.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF263 MUTATED 1 2 1 0
ZNF263 WILD-TYPE 13 45 20 30
'ZNF263 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.065 (Fisher's exact test), Q value = 0.31

Table S411.  Gene #36: 'ZNF263 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF263 MUTATED 3 0 1
ZNF263 WILD-TYPE 31 53 24
'INTS7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.502 (Fisher's exact test), Q value = 0.83

Table S412.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
INTS7 MUTATED 2 1 0 0
INTS7 WILD-TYPE 11 17 13 7
'INTS7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.63

Table S413.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
INTS7 MUTATED 1 0 1 1 0
INTS7 WILD-TYPE 11 10 6 6 15
'INTS7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0815 (Fisher's exact test), Q value = 0.34

Table S414.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
INTS7 MUTATED 0 6 1 1
INTS7 WILD-TYPE 71 81 53 29
'INTS7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 0.53

Table S415.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
INTS7 MUTATED 0 2 2 2 2 0 0
INTS7 WILD-TYPE 24 48 29 17 20 33 24
'INTS7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 0.47

Table S416.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
INTS7 MUTATED 1 4 3 0
INTS7 WILD-TYPE 67 74 28 26
'INTS7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0468 (Fisher's exact test), Q value = 0.26

Table S417.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
INTS7 MUTATED 1 5 2 0
INTS7 WILD-TYPE 63 68 34 74

Figure S134.  Get High-res Image Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'INTS7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00514 (Fisher's exact test), Q value = 0.064

Table S418.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
INTS7 MUTATED 0 1 0 2 5 0 0
INTS7 WILD-TYPE 44 40 17 31 30 31 46

Figure S135.  Get High-res Image Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'INTS7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.48

Table S419.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
INTS7 MUTATED 0 1 5 1 0
INTS7 WILD-TYPE 41 39 59 74 20
'INTS7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0474 (Fisher's exact test), Q value = 0.26

Table S420.  Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
INTS7 MUTATED 6 1 0
INTS7 WILD-TYPE 98 54 81

Figure S136.  Get High-res Image Gene #37: 'INTS7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'L1TD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00109 (Fisher's exact test), Q value = 0.024

Table S421.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
L1TD1 MUTATED 0 12 4 0
L1TD1 WILD-TYPE 71 75 50 30

Figure S137.  Get High-res Image Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'L1TD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0717 (Fisher's exact test), Q value = 0.32

Table S422.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
L1TD1 MUTATED 2 0 8
L1TD1 WILD-TYPE 42 28 55
'L1TD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 0.53

Table S423.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
L1TD1 MUTATED 1 1 4 3 2 1 1
L1TD1 WILD-TYPE 23 49 27 16 20 32 23
'L1TD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.37 (Fisher's exact test), Q value = 0.71

Table S424.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
L1TD1 MUTATED 2 7 3 1
L1TD1 WILD-TYPE 66 71 28 25
'L1TD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.62

Table S425.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
L1TD1 MUTATED 3 5 5 3
L1TD1 WILD-TYPE 61 68 31 71
'L1TD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00109 (Fisher's exact test), Q value = 0.024

Table S426.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
L1TD1 MUTATED 0 1 1 5 7 0 2
L1TD1 WILD-TYPE 44 40 16 28 28 31 44

Figure S138.  Get High-res Image Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'L1TD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.61

Table S427.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
L1TD1 MUTATED 1 2 8 3 1
L1TD1 WILD-TYPE 40 38 56 72 19
'L1TD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.53

Table S428.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
L1TD1 MUTATED 10 2 3
L1TD1 WILD-TYPE 94 53 78
'L1TD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S429.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
L1TD1 MUTATED 0 3 1 3
L1TD1 WILD-TYPE 14 44 20 27
'L1TD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 0.9

Table S430.  Gene #38: 'L1TD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
L1TD1 MUTATED 3 2 2
L1TD1 WILD-TYPE 31 51 23
'NAT1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 0.83

Table S431.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
NAT1 MUTATED 2 1 0 0
NAT1 WILD-TYPE 11 17 13 7
'NAT1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0792 (Fisher's exact test), Q value = 0.33

Table S432.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
NAT1 MUTATED 1 0 0 2 0
NAT1 WILD-TYPE 11 10 7 5 15
'NAT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 0.47

Table S433.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NAT1 MUTATED 0 5 1 1
NAT1 WILD-TYPE 71 82 53 29
'NAT1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 0.92

Table S434.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NAT1 MUTATED 1 1 2 1 0 0 1
NAT1 WILD-TYPE 23 49 29 18 22 33 23
'NAT1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S435.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NAT1 MUTATED 2 2 1 1
NAT1 WILD-TYPE 66 76 30 25
'NAT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 0.88

Table S436.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NAT1 MUTATED 2 2 2 1
NAT1 WILD-TYPE 62 71 34 73
'NAT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00216 (Fisher's exact test), Q value = 0.037

Table S437.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NAT1 MUTATED 0 0 0 3 4 0 0
NAT1 WILD-TYPE 44 41 17 30 31 31 46

Figure S139.  Get High-res Image Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NAT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.492 (Fisher's exact test), Q value = 0.83

Table S438.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NAT1 MUTATED 0 1 4 2 0
NAT1 WILD-TYPE 41 39 60 73 20
'NAT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S439.  Gene #39: 'NAT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NAT1 MUTATED 4 1 2
NAT1 WILD-TYPE 100 54 79
'JAKMIP2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 0.83

Table S440.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
JAKMIP2 MUTATED 2 1 0 0
JAKMIP2 WILD-TYPE 11 17 13 7
'JAKMIP2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.284 (Fisher's exact test), Q value = 0.63

Table S441.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
JAKMIP2 MUTATED 1 0 1 1 0
JAKMIP2 WILD-TYPE 11 10 6 6 15
'JAKMIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.47

Table S442.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
JAKMIP2 MUTATED 1 8 2 1
JAKMIP2 WILD-TYPE 70 79 52 29
'JAKMIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S443.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
JAKMIP2 MUTATED 2 0 2
JAKMIP2 WILD-TYPE 42 28 61
'JAKMIP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 0.62

Table S444.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
JAKMIP2 MUTATED 0 2 4 1 2 1 0
JAKMIP2 WILD-TYPE 24 48 27 18 20 32 24
'JAKMIP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 0.38

Table S445.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
JAKMIP2 MUTATED 1 6 3 0
JAKMIP2 WILD-TYPE 67 72 28 26
'JAKMIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 0.38

Table S446.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
JAKMIP2 MUTATED 2 5 4 1
JAKMIP2 WILD-TYPE 62 68 32 73
'JAKMIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00065 (Fisher's exact test), Q value = 0.017

Table S447.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
JAKMIP2 MUTATED 0 0 2 3 6 0 1
JAKMIP2 WILD-TYPE 44 41 15 30 29 31 45

Figure S140.  Get High-res Image Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'JAKMIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0865 (Fisher's exact test), Q value = 0.35

Table S448.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
JAKMIP2 MUTATED 1 1 7 1 1
JAKMIP2 WILD-TYPE 40 39 57 74 19
'JAKMIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.51

Table S449.  Gene #40: 'JAKMIP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
JAKMIP2 MUTATED 7 3 1
JAKMIP2 WILD-TYPE 97 52 80
'ING1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0145 (Fisher's exact test), Q value = 0.13

Table S450.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ING1 MUTATED 0 8 4 0
ING1 WILD-TYPE 71 79 50 30

Figure S141.  Get High-res Image Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ING1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S451.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ING1 MUTATED 3 1 3
ING1 WILD-TYPE 41 27 60
'ING1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.284 (Fisher's exact test), Q value = 0.63

Table S452.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ING1 MUTATED 3 1 4 0 1 2 1
ING1 WILD-TYPE 21 49 27 19 21 31 23
'ING1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.676 (Fisher's exact test), Q value = 0.96

Table S453.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ING1 MUTATED 5 5 2 0
ING1 WILD-TYPE 63 73 29 26
'ING1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 0.76

Table S454.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ING1 MUTATED 1 4 3 4
ING1 WILD-TYPE 63 69 33 70
'ING1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0566 (Fisher's exact test), Q value = 0.28

Table S455.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ING1 MUTATED 0 1 1 2 5 0 3
ING1 WILD-TYPE 44 40 16 31 30 31 43
'ING1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 0.86

Table S456.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ING1 MUTATED 1 1 2 5 2
ING1 WILD-TYPE 40 39 62 70 18
'ING1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.577 (Fisher's exact test), Q value = 0.88

Table S457.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ING1 MUTATED 5 1 5
ING1 WILD-TYPE 99 54 76
'ING1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.298 (Fisher's exact test), Q value = 0.64

Table S458.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ING1 MUTATED 0 2 3 1
ING1 WILD-TYPE 14 45 18 29
'ING1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.658 (Fisher's exact test), Q value = 0.95

Table S459.  Gene #41: 'ING1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ING1 MUTATED 2 2 2
ING1 WILD-TYPE 32 51 23
'CCDC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.564 (Fisher's exact test), Q value = 0.87

Table S460.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CCDC6 MUTATED 2 3 0 1
CCDC6 WILD-TYPE 69 84 54 29
'CCDC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 0.38

Table S461.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CCDC6 MUTATED 4 0 1
CCDC6 WILD-TYPE 40 28 62
'CCDC6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 0.83

Table S462.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CCDC6 MUTATED 1 0 1 0 1 2 1
CCDC6 WILD-TYPE 23 50 30 19 21 31 23
'CCDC6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.48 (Fisher's exact test), Q value = 0.82

Table S463.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CCDC6 MUTATED 1 2 2 1
CCDC6 WILD-TYPE 67 76 29 25
'CCDC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S464.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CCDC6 MUTATED 2 1 1 2
CCDC6 WILD-TYPE 62 72 35 72
'CCDC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.241 (Fisher's exact test), Q value = 0.59

Table S465.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CCDC6 MUTATED 1 0 2 1 1 0 1
CCDC6 WILD-TYPE 43 41 15 32 34 31 45
'CCDC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 0.98

Table S466.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CCDC6 MUTATED 2 0 2 2 0
CCDC6 WILD-TYPE 39 40 62 73 20
'CCDC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00797 (Fisher's exact test), Q value = 0.085

Table S467.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CCDC6 MUTATED 0 4 2
CCDC6 WILD-TYPE 104 51 79

Figure S142.  Get High-res Image Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CCDC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 0.92

Table S468.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CCDC6 MUTATED 1 2 0 2
CCDC6 WILD-TYPE 13 45 21 28
'CCDC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0601 (Fisher's exact test), Q value = 0.3

Table S469.  Gene #42: 'CCDC6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CCDC6 MUTATED 4 1 0
CCDC6 WILD-TYPE 30 52 25
'ZNF781 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00308 (Fisher's exact test), Q value = 0.046

Table S470.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF781 MUTATED 0 9 1 0
ZNF781 WILD-TYPE 71 78 53 30

Figure S143.  Get High-res Image Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF781 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 0.88

Table S471.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF781 MUTATED 1 2 3
ZNF781 WILD-TYPE 43 26 60
'ZNF781 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 0.51

Table S472.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF781 MUTATED 1 0 3 2 1 1 2
ZNF781 WILD-TYPE 23 50 28 17 21 32 22
'ZNF781 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.688 (Fisher's exact test), Q value = 0.97

Table S473.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF781 MUTATED 2 4 2 2
ZNF781 WILD-TYPE 66 74 29 24
'ZNF781 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 0.52

Table S474.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF781 MUTATED 2 2 4 2
ZNF781 WILD-TYPE 62 71 32 72
'ZNF781 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0136 (Fisher's exact test), Q value = 0.12

Table S475.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF781 MUTATED 1 0 0 5 3 0 1
ZNF781 WILD-TYPE 43 41 17 28 32 31 45

Figure S144.  Get High-res Image Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF781 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.63

Table S476.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF781 MUTATED 0 1 5 2 1
ZNF781 WILD-TYPE 41 39 59 73 19
'ZNF781 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S477.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF781 MUTATED 5 2 2
ZNF781 WILD-TYPE 99 53 79
'ZNF781 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S478.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF781 MUTATED 0 2 1 2
ZNF781 WILD-TYPE 14 45 20 28
'ZNF781 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.433 (Fisher's exact test), Q value = 0.77

Table S479.  Gene #43: 'ZNF781 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF781 MUTATED 2 1 2
ZNF781 WILD-TYPE 32 52 23
'MKI67 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00339 (Fisher's exact test), Q value = 0.049

Table S480.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MKI67 MUTATED 7 4 0 0
MKI67 WILD-TYPE 6 14 13 7

Figure S145.  Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'MKI67 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0162 (Fisher's exact test), Q value = 0.14

Table S481.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MKI67 MUTATED 4 0 2 4 1
MKI67 WILD-TYPE 8 10 5 3 14

Figure S146.  Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MKI67 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S482.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MKI67 MUTATED 0 20 6 3
MKI67 WILD-TYPE 71 67 48 27

Figure S147.  Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MKI67 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 0.99

Table S483.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MKI67 MUTATED 3 2 7
MKI67 WILD-TYPE 41 26 56
'MKI67 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.984 (Fisher's exact test), Q value = 1

Table S484.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MKI67 MUTATED 3 6 5 3 3 5 2
MKI67 WILD-TYPE 21 44 26 16 19 28 22
'MKI67 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.674 (Fisher's exact test), Q value = 0.96

Table S485.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MKI67 MUTATED 11 9 5 2
MKI67 WILD-TYPE 57 69 26 24
'MKI67 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 0.53

Table S486.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MKI67 MUTATED 5 11 7 6
MKI67 WILD-TYPE 59 62 29 68
'MKI67 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00031 (Fisher's exact test), Q value = 0.01

Table S487.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MKI67 MUTATED 1 3 2 11 8 1 3
MKI67 WILD-TYPE 43 38 15 22 27 30 43

Figure S148.  Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MKI67 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0148 (Fisher's exact test), Q value = 0.13

Table S488.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MKI67 MUTATED 1 3 15 7 2
MKI67 WILD-TYPE 40 37 49 68 18

Figure S149.  Get High-res Image Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'MKI67 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 0.64

Table S489.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MKI67 MUTATED 16 4 8
MKI67 WILD-TYPE 88 51 73
'MKI67 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 0.95

Table S490.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MKI67 MUTATED 2 3 2 4
MKI67 WILD-TYPE 12 44 19 26
'MKI67 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.318 (Fisher's exact test), Q value = 0.66

Table S491.  Gene #44: 'MKI67 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MKI67 MUTATED 4 3 4
MKI67 WILD-TYPE 30 50 21
'EIF2S2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0371 (Fisher's exact test), Q value = 0.23

Table S492.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
EIF2S2 MUTATED 0 7 2 0
EIF2S2 WILD-TYPE 71 80 52 30

Figure S150.  Get High-res Image Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'EIF2S2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S493.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
EIF2S2 MUTATED 1 1 3
EIF2S2 WILD-TYPE 43 27 60
'EIF2S2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 0.83

Table S494.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
EIF2S2 MUTATED 0 1 2 2 1 1 2
EIF2S2 WILD-TYPE 24 49 29 17 21 32 22
'EIF2S2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 0.47

Table S495.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
EIF2S2 MUTATED 1 3 3 2
EIF2S2 WILD-TYPE 67 75 28 24
'EIF2S2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S496.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
EIF2S2 MUTATED 1 4 3 1
EIF2S2 WILD-TYPE 63 69 33 73
'EIF2S2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.375 (Fisher's exact test), Q value = 0.72

Table S497.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
EIF2S2 MUTATED 1 1 1 2 3 1 0
EIF2S2 WILD-TYPE 43 40 16 31 32 30 46
'EIF2S2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.46

Table S498.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
EIF2S2 MUTATED 0 1 6 2 0
EIF2S2 WILD-TYPE 41 39 58 73 20
'EIF2S2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 0.66

Table S499.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
EIF2S2 MUTATED 5 3 1
EIF2S2 WILD-TYPE 99 52 80
'EIF2S2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.61

Table S500.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
EIF2S2 MUTATED 0 1 0 3
EIF2S2 WILD-TYPE 14 46 21 27
'EIF2S2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 0.87

Table S501.  Gene #45: 'EIF2S2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
EIF2S2 MUTATED 2 1 1
EIF2S2 WILD-TYPE 32 52 24
'BCOR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S502.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
BCOR MUTATED 1 2 0 0
BCOR WILD-TYPE 12 16 13 7
'BCOR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.53

Table S503.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
BCOR MUTATED 2 0 0 1 0
BCOR WILD-TYPE 10 10 7 6 15
'BCOR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00169 (Fisher's exact test), Q value = 0.032

Table S504.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
BCOR MUTATED 1 15 10 3
BCOR WILD-TYPE 70 72 44 27

Figure S151.  Get High-res Image Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'BCOR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 0.37

Table S505.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
BCOR MUTATED 2 2 11
BCOR WILD-TYPE 42 26 52
'BCOR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.999 (Fisher's exact test), Q value = 1

Table S506.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
BCOR MUTATED 3 7 3 2 2 4 3
BCOR WILD-TYPE 21 43 28 17 20 29 21
'BCOR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.317 (Fisher's exact test), Q value = 0.66

Table S507.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
BCOR MUTATED 11 6 5 2
BCOR WILD-TYPE 57 72 26 24
'BCOR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0011 (Fisher's exact test), Q value = 0.024

Table S508.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
BCOR MUTATED 2 16 7 5
BCOR WILD-TYPE 62 57 29 69

Figure S152.  Get High-res Image Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'BCOR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00459 (Fisher's exact test), Q value = 0.06

Table S509.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
BCOR MUTATED 0 6 2 8 8 2 4
BCOR WILD-TYPE 44 35 15 25 27 29 42

Figure S153.  Get High-res Image Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'BCOR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.46

Table S510.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
BCOR MUTATED 2 4 13 7 3
BCOR WILD-TYPE 39 36 51 68 17
'BCOR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0483 (Fisher's exact test), Q value = 0.26

Table S511.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
BCOR MUTATED 19 4 6
BCOR WILD-TYPE 85 51 75

Figure S154.  Get High-res Image Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'BCOR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 0.66

Table S512.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
BCOR MUTATED 0 4 4 4
BCOR WILD-TYPE 14 43 17 26
'BCOR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S513.  Gene #46: 'BCOR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
BCOR MUTATED 3 7 2
BCOR WILD-TYPE 31 46 23
'RASA1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.641 (Fisher's exact test), Q value = 0.94

Table S514.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
RASA1 MUTATED 3 2 1 0
RASA1 WILD-TYPE 10 16 12 7
'RASA1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 0.7

Table S515.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
RASA1 MUTATED 2 0 1 2 1
RASA1 WILD-TYPE 10 10 6 5 14
'RASA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00842 (Fisher's exact test), Q value = 0.089

Table S516.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RASA1 MUTATED 1 14 4 2
RASA1 WILD-TYPE 70 73 50 28

Figure S155.  Get High-res Image Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RASA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S517.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RASA1 MUTATED 3 1 4
RASA1 WILD-TYPE 41 27 59
'RASA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.995 (Fisher's exact test), Q value = 1

Table S518.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RASA1 MUTATED 2 5 3 2 2 3 1
RASA1 WILD-TYPE 22 45 28 17 20 30 23
'RASA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S519.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RASA1 MUTATED 6 6 4 2
RASA1 WILD-TYPE 62 72 27 24
'RASA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 0.66

Table S520.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RASA1 MUTATED 3 8 5 5
RASA1 WILD-TYPE 61 65 31 69
'RASA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0605 (Fisher's exact test), Q value = 0.3

Table S521.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RASA1 MUTATED 2 2 2 7 4 0 4
RASA1 WILD-TYPE 42 39 15 26 31 31 42
'RASA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 0.67

Table S522.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RASA1 MUTATED 1 3 9 6 1
RASA1 WILD-TYPE 40 37 55 69 19
'RASA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.693 (Fisher's exact test), Q value = 0.97

Table S523.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RASA1 MUTATED 10 5 5
RASA1 WILD-TYPE 94 50 76
'RASA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 0.77

Table S524.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RASA1 MUTATED 1 2 1 4
RASA1 WILD-TYPE 13 45 20 26
'RASA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.085 (Fisher's exact test), Q value = 0.35

Table S525.  Gene #47: 'RASA1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RASA1 MUTATED 4 1 3
RASA1 WILD-TYPE 30 52 22
'DNER MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 0.65

Table S526.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
DNER MUTATED 3 2 0 0
DNER WILD-TYPE 10 16 13 7
'DNER MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0931 (Fisher's exact test), Q value = 0.36

Table S527.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
DNER MUTATED 2 0 2 1 0
DNER WILD-TYPE 10 10 5 6 15
'DNER MUTATION STATUS' versus 'CN_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.46

Table S528.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
DNER MUTATED 2 10 5 1
DNER WILD-TYPE 69 77 49 29
'DNER MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S529.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
DNER MUTATED 3 1 4
DNER WILD-TYPE 41 27 59
'DNER MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.248 (Fisher's exact test), Q value = 0.6

Table S530.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
DNER MUTATED 2 3 6 1 1 2 0
DNER WILD-TYPE 22 47 25 18 21 31 24
'DNER MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S531.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
DNER MUTATED 4 7 3 1
DNER WILD-TYPE 64 71 28 25
'DNER MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.4

Table S532.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
DNER MUTATED 2 5 6 5
DNER WILD-TYPE 62 68 30 69
'DNER MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00035 (Fisher's exact test), Q value = 0.011

Table S533.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
DNER MUTATED 0 0 2 5 7 0 4
DNER WILD-TYPE 44 41 15 28 28 31 42

Figure S156.  Get High-res Image Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'DNER MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 0.59

Table S534.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
DNER MUTATED 1 1 8 5 2
DNER WILD-TYPE 40 39 56 70 18
'DNER MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.95 (Fisher's exact test), Q value = 1

Table S535.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
DNER MUTATED 8 4 5
DNER WILD-TYPE 96 51 76
'DNER MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S536.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
DNER MUTATED 0 4 1 2
DNER WILD-TYPE 14 43 20 28
'DNER MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S537.  Gene #48: 'DNER MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
DNER MUTATED 2 3 2
DNER WILD-TYPE 32 50 23
'C9ORF23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 0.46

Table S538.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
C9ORF23 MUTATED 0 4 2 2
C9ORF23 WILD-TYPE 71 83 52 28
'C9ORF23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.54

Table S539.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
C9ORF23 MUTATED 2 0 6
C9ORF23 WILD-TYPE 42 28 57
'C9ORF23 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 0.92

Table S540.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
C9ORF23 MUTATED 2 1 2 1 0 1 2
C9ORF23 WILD-TYPE 22 49 29 18 22 32 22
'C9ORF23 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.633 (Fisher's exact test), Q value = 0.93

Table S541.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
C9ORF23 MUTATED 3 5 0 1
C9ORF23 WILD-TYPE 65 73 31 25
'C9ORF23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 0.68

Table S542.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
C9ORF23 MUTATED 1 2 3 3
C9ORF23 WILD-TYPE 63 71 33 71
'C9ORF23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0798 (Fisher's exact test), Q value = 0.33

Table S543.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
C9ORF23 MUTATED 0 0 1 4 1 1 2
C9ORF23 WILD-TYPE 44 41 16 29 34 30 44
'C9ORF23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.569 (Fisher's exact test), Q value = 0.88

Table S544.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
C9ORF23 MUTATED 1 0 4 3 1
C9ORF23 WILD-TYPE 40 40 60 72 19
'C9ORF23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S545.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
C9ORF23 MUTATED 5 1 3
C9ORF23 WILD-TYPE 99 54 78
'C9ORF23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S546.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
C9ORF23 MUTATED 0 3 1 2
C9ORF23 WILD-TYPE 14 44 20 28
'C9ORF23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.659 (Fisher's exact test), Q value = 0.95

Table S547.  Gene #49: 'C9ORF23 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
C9ORF23 MUTATED 2 2 2
C9ORF23 WILD-TYPE 32 51 23
'CUX1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S548.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CUX1 MUTATED 1 2 1 1
CUX1 WILD-TYPE 12 16 12 6
'CUX1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.654 (Fisher's exact test), Q value = 0.95

Table S549.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CUX1 MUTATED 2 0 1 1 1
CUX1 WILD-TYPE 10 10 6 6 14
'CUX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 9e-05 (Fisher's exact test), Q value = 0.0042

Table S550.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CUX1 MUTATED 0 16 2 3
CUX1 WILD-TYPE 71 71 52 27

Figure S157.  Get High-res Image Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CUX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.509 (Fisher's exact test), Q value = 0.83

Table S551.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CUX1 MUTATED 3 1 7
CUX1 WILD-TYPE 41 27 56
'CUX1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S552.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CUX1 MUTATED 3 4 4 1 1 2 2
CUX1 WILD-TYPE 21 46 27 18 21 31 22
'CUX1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S553.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CUX1 MUTATED 5 6 4 2
CUX1 WILD-TYPE 63 72 27 24
'CUX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 0.66

Table S554.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CUX1 MUTATED 3 8 5 5
CUX1 WILD-TYPE 61 65 31 69
'CUX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00262 (Fisher's exact test), Q value = 0.041

Table S555.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CUX1 MUTATED 1 1 2 7 7 2 1
CUX1 WILD-TYPE 43 40 15 26 28 29 45

Figure S158.  Get High-res Image Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CUX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0307 (Fisher's exact test), Q value = 0.21

Table S556.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CUX1 MUTATED 1 2 11 3 2
CUX1 WILD-TYPE 40 38 53 72 18

Figure S159.  Get High-res Image Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CUX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 0.7

Table S557.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CUX1 MUTATED 11 4 4
CUX1 WILD-TYPE 93 51 77
'CUX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.52

Table S558.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CUX1 MUTATED 0 2 2 5
CUX1 WILD-TYPE 14 45 19 25
'CUX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 0.91

Table S559.  Gene #50: 'CUX1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CUX1 MUTATED 4 3 2
CUX1 WILD-TYPE 30 50 23
'CDK17 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.1 (Fisher's exact test), Q value = 0.37

Table S560.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CDK17 MUTATED 3 0 2 0
CDK17 WILD-TYPE 10 18 11 7
'CDK17 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0019 (Fisher's exact test), Q value = 0.034

Table S561.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CDK17 MUTATED 0 0 3 2 0
CDK17 WILD-TYPE 12 10 4 5 15

Figure S160.  Get High-res Image Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CDK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.149 (Fisher's exact test), Q value = 0.46

Table S562.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CDK17 MUTATED 1 7 5 1
CDK17 WILD-TYPE 70 80 49 29
'CDK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 0.41

Table S563.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CDK17 MUTATED 0 1 5
CDK17 WILD-TYPE 44 27 58
'CDK17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 0.87

Table S564.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CDK17 MUTATED 2 1 3 1 0 2 2
CDK17 WILD-TYPE 22 49 28 18 22 31 22
'CDK17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.968 (Fisher's exact test), Q value = 1

Table S565.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CDK17 MUTATED 4 5 1 1
CDK17 WILD-TYPE 64 73 30 25
'CDK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S566.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CDK17 MUTATED 3 4 3 4
CDK17 WILD-TYPE 61 69 33 70
'CDK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0298 (Fisher's exact test), Q value = 0.2

Table S567.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CDK17 MUTATED 1 1 2 5 2 3 0
CDK17 WILD-TYPE 43 40 15 28 33 28 46

Figure S161.  Get High-res Image Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CDK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.18 (Fisher's exact test), Q value = 0.51

Table S568.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CDK17 MUTATED 1 2 8 3 0
CDK17 WILD-TYPE 40 38 56 72 20
'CDK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S569.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CDK17 MUTATED 7 3 4
CDK17 WILD-TYPE 97 52 77
'CDK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 0.79

Table S570.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CDK17 MUTATED 1 2 0 3
CDK17 WILD-TYPE 13 45 21 27
'CDK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0135 (Fisher's exact test), Q value = 0.12

Table S571.  Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CDK17 MUTATED 3 0 3
CDK17 WILD-TYPE 31 53 22

Figure S162.  Get High-res Image Gene #51: 'CDK17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'USP28 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0189 (Fisher's exact test), Q value = 0.15

Table S572.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
USP28 MUTATED 0 8 1 1
USP28 WILD-TYPE 71 79 53 29

Figure S163.  Get High-res Image Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'USP28 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.711 (Fisher's exact test), Q value = 0.98

Table S573.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
USP28 MUTATED 2 0 3
USP28 WILD-TYPE 42 28 60
'USP28 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S574.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
USP28 MUTATED 1 2 3 0 0 2 1
USP28 WILD-TYPE 23 48 28 19 22 31 23
'USP28 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.473 (Fisher's exact test), Q value = 0.81

Table S575.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
USP28 MUTATED 2 3 3 1
USP28 WILD-TYPE 66 75 28 25
'USP28 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.65

Table S576.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
USP28 MUTATED 1 4 3 2
USP28 WILD-TYPE 63 69 33 72
'USP28 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00926 (Fisher's exact test), Q value = 0.095

Table S577.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
USP28 MUTATED 0 0 1 4 3 2 0
USP28 WILD-TYPE 44 41 16 29 32 29 46

Figure S164.  Get High-res Image Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'USP28 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 0.47

Table S578.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
USP28 MUTATED 0 1 6 2 1
USP28 WILD-TYPE 41 39 58 73 19
'USP28 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 0.91

Table S579.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
USP28 MUTATED 6 2 2
USP28 WILD-TYPE 98 53 79
'USP28 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S580.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
USP28 MUTATED 0 2 0 1
USP28 WILD-TYPE 14 45 21 29
'USP28 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0367 (Fisher's exact test), Q value = 0.23

Table S581.  Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
USP28 MUTATED 3 0 0
USP28 WILD-TYPE 31 53 25

Figure S165.  Get High-res Image Gene #52: 'USP28 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MSH6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 0.83

Table S582.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MSH6 MUTATED 2 1 0 0
MSH6 WILD-TYPE 11 17 13 7
'MSH6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.286 (Fisher's exact test), Q value = 0.63

Table S583.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MSH6 MUTATED 1 0 1 1 0
MSH6 WILD-TYPE 11 10 6 6 15
'MSH6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.53

Table S584.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MSH6 MUTATED 2 10 3 2
MSH6 WILD-TYPE 69 77 51 28
'MSH6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S585.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MSH6 MUTATED 2 1 4
MSH6 WILD-TYPE 42 27 59
'MSH6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 0.91

Table S586.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MSH6 MUTATED 2 2 5 1 2 2 1
MSH6 WILD-TYPE 22 48 26 18 20 31 23
'MSH6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 0.84

Table S587.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MSH6 MUTATED 3 8 3 1
MSH6 WILD-TYPE 65 70 28 25
'MSH6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 0.37

Table S588.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MSH6 MUTATED 3 7 5 2
MSH6 WILD-TYPE 61 66 31 72
'MSH6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00015 (Fisher's exact test), Q value = 0.0061

Table S589.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MSH6 MUTATED 1 0 2 6 7 0 1
MSH6 WILD-TYPE 43 41 15 27 28 31 45

Figure S166.  Get High-res Image Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MSH6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.145 (Fisher's exact test), Q value = 0.46

Table S590.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MSH6 MUTATED 2 1 9 3 1
MSH6 WILD-TYPE 39 39 55 72 19
'MSH6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 0.78

Table S591.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MSH6 MUTATED 9 4 3
MSH6 WILD-TYPE 95 51 78
'MSH6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S592.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MSH6 MUTATED 0 2 1 1
MSH6 WILD-TYPE 14 45 20 29
'MSH6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.561 (Fisher's exact test), Q value = 0.87

Table S593.  Gene #53: 'MSH6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MSH6 MUTATED 2 1 1
MSH6 WILD-TYPE 32 52 24
'WDR45 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 0.56

Table S594.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
WDR45 MUTATED 1 5 2 3
WDR45 WILD-TYPE 70 82 52 27
'WDR45 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.572 (Fisher's exact test), Q value = 0.88

Table S595.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
WDR45 MUTATED 1 2 3
WDR45 WILD-TYPE 43 26 60
'WDR45 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S596.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
WDR45 MUTATED 1 3 2 1 1 2 0
WDR45 WILD-TYPE 23 47 29 18 21 31 24
'WDR45 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 0.89

Table S597.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
WDR45 MUTATED 3 6 1 0
WDR45 WILD-TYPE 65 72 30 26
'WDR45 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.529 (Fisher's exact test), Q value = 0.85

Table S598.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
WDR45 MUTATED 2 4 3 2
WDR45 WILD-TYPE 62 69 33 72
'WDR45 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.24 (Fisher's exact test), Q value = 0.59

Table S599.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
WDR45 MUTATED 1 0 0 4 2 2 2
WDR45 WILD-TYPE 43 41 17 29 33 29 44
'WDR45 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 0.98

Table S600.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
WDR45 MUTATED 1 1 5 3 1
WDR45 WILD-TYPE 40 39 59 72 19
'WDR45 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.668 (Fisher's exact test), Q value = 0.96

Table S601.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
WDR45 MUTATED 6 1 4
WDR45 WILD-TYPE 98 54 77
'WDR45 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0585 (Fisher's exact test), Q value = 0.29

Table S602.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
WDR45 MUTATED 0 1 3 0
WDR45 WILD-TYPE 14 46 18 30
'WDR45 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 0.61

Table S603.  Gene #54: 'WDR45 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
WDR45 MUTATED 0 2 2
WDR45 WILD-TYPE 34 51 23
'C14ORF166B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0585 (Fisher's exact test), Q value = 0.29

Table S604.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
C14ORF166B MUTATED 0 6 3 0
C14ORF166B WILD-TYPE 71 81 51 30
'C14ORF166B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 0.45

Table S605.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
C14ORF166B MUTATED 0 0 4
C14ORF166B WILD-TYPE 44 28 59
'C14ORF166B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 0.99

Table S606.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
C14ORF166B MUTATED 1 1 2 1 1 0 1
C14ORF166B WILD-TYPE 23 49 29 18 21 33 23
'C14ORF166B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S607.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
C14ORF166B MUTATED 2 2 2 1
C14ORF166B WILD-TYPE 66 76 29 25
'C14ORF166B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 0.68

Table S608.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
C14ORF166B MUTATED 1 2 3 3
C14ORF166B WILD-TYPE 63 71 33 71
'C14ORF166B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.023 (Fisher's exact test), Q value = 0.17

Table S609.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
C14ORF166B MUTATED 0 0 0 3 4 0 2
C14ORF166B WILD-TYPE 44 41 17 30 31 31 44

Figure S167.  Get High-res Image Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'C14ORF166B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 0.84

Table S610.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
C14ORF166B MUTATED 0 1 4 3 0
C14ORF166B WILD-TYPE 41 39 60 72 20
'C14ORF166B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S611.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
C14ORF166B MUTATED 4 1 3
C14ORF166B WILD-TYPE 100 54 78
'C14ORF166B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S612.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
C14ORF166B MUTATED 0 2 0 1
C14ORF166B WILD-TYPE 14 45 21 29
'C14ORF166B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S613.  Gene #55: 'C14ORF166B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
C14ORF166B MUTATED 1 1 1
C14ORF166B WILD-TYPE 33 52 24
'ATM MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0282 (Fisher's exact test), Q value = 0.2

Table S614.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ATM MUTATED 6 2 1 0
ATM WILD-TYPE 7 16 12 7

Figure S168.  Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'ATM MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00023 (Fisher's exact test), Q value = 0.0082

Table S615.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ATM MUTATED 2 0 2 5 0
ATM WILD-TYPE 10 10 5 2 15

Figure S169.  Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'ATM MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00308 (Fisher's exact test), Q value = 0.046

Table S616.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ATM MUTATED 2 18 4 3
ATM WILD-TYPE 69 69 50 27

Figure S170.  Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ATM MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S617.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ATM MUTATED 4 2 6
ATM WILD-TYPE 40 26 57
'ATM MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 0.91

Table S618.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ATM MUTATED 3 6 7 2 3 3 1
ATM WILD-TYPE 21 44 24 17 19 30 23
'ATM MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.535 (Fisher's exact test), Q value = 0.85

Table S619.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ATM MUTATED 9 10 5 1
ATM WILD-TYPE 59 68 26 25
'ATM MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.195 (Fisher's exact test), Q value = 0.53

Table S620.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ATM MUTATED 4 12 6 7
ATM WILD-TYPE 60 61 30 67
'ATM MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00036 (Fisher's exact test), Q value = 0.012

Table S621.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ATM MUTATED 1 2 3 8 10 3 2
ATM WILD-TYPE 43 39 14 25 25 28 44

Figure S171.  Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ATM MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0281 (Fisher's exact test), Q value = 0.2

Table S622.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ATM MUTATED 1 3 14 9 1
ATM WILD-TYPE 40 37 50 66 19

Figure S172.  Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ATM MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S623.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ATM MUTATED 13 6 9
ATM WILD-TYPE 91 49 72
'ATM MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S624.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ATM MUTATED 2 4 2 4
ATM WILD-TYPE 12 43 19 26
'ATM MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.041 (Fisher's exact test), Q value = 0.24

Table S625.  Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ATM MUTATED 7 2 3
ATM WILD-TYPE 27 51 22

Figure S173.  Get High-res Image Gene #56: 'ATM MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RAE1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 0.79

Table S626.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
RAE1 MUTATED 1 3 0 0
RAE1 WILD-TYPE 12 15 13 7
'RAE1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.078 (Fisher's exact test), Q value = 0.33

Table S627.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
RAE1 MUTATED 3 0 1 0 0
RAE1 WILD-TYPE 9 10 6 7 15
'RAE1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.66

Table S628.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RAE1 MUTATED 1 6 2 2
RAE1 WILD-TYPE 70 81 52 28
'RAE1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 0.83

Table S629.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RAE1 MUTATED 1 0 4
RAE1 WILD-TYPE 43 28 59
'RAE1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.635 (Fisher's exact test), Q value = 0.93

Table S630.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RAE1 MUTATED 2 1 2 0 2 1 1
RAE1 WILD-TYPE 22 49 29 19 20 32 23
'RAE1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.678 (Fisher's exact test), Q value = 0.96

Table S631.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RAE1 MUTATED 4 2 2 1
RAE1 WILD-TYPE 64 76 29 25
'RAE1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 0.9

Table S632.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RAE1 MUTATED 3 3 3 2
RAE1 WILD-TYPE 61 70 33 72
'RAE1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0176 (Fisher's exact test), Q value = 0.14

Table S633.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RAE1 MUTATED 1 0 1 4 4 1 0
RAE1 WILD-TYPE 43 41 16 29 31 30 46

Figure S174.  Get High-res Image Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RAE1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.49

Table S634.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RAE1 MUTATED 2 0 6 2 0
RAE1 WILD-TYPE 39 40 58 73 20
'RAE1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 0.95

Table S635.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RAE1 MUTATED 5 3 2
RAE1 WILD-TYPE 99 52 79
'RAE1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.46

Table S636.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RAE1 MUTATED 2 1 0 2
RAE1 WILD-TYPE 12 46 21 28
'RAE1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 0.77

Table S637.  Gene #57: 'RAE1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RAE1 MUTATED 2 1 2
RAE1 WILD-TYPE 32 52 23
'ZNF485 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S638.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZNF485 MUTATED 1 1 1 0
ZNF485 WILD-TYPE 12 17 12 7
'ZNF485 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0792 (Fisher's exact test), Q value = 0.33

Table S639.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZNF485 MUTATED 1 0 2 0 0
ZNF485 WILD-TYPE 11 10 5 7 15
'ZNF485 MUTATION STATUS' versus 'CN_CNMF'

P value = 8e-04 (Fisher's exact test), Q value = 0.02

Table S640.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF485 MUTATED 0 9 0 0
ZNF485 WILD-TYPE 71 78 54 30

Figure S175.  Get High-res Image Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF485 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S641.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF485 MUTATED 1 1 2
ZNF485 WILD-TYPE 43 27 61
'ZNF485 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.475 (Fisher's exact test), Q value = 0.81

Table S642.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF485 MUTATED 0 1 1 2 1 1 2
ZNF485 WILD-TYPE 24 49 30 17 21 32 22
'ZNF485 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 0.66

Table S643.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF485 MUTATED 1 3 2 2
ZNF485 WILD-TYPE 67 75 29 24
'ZNF485 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 0.77

Table S644.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF485 MUTATED 2 2 3 2
ZNF485 WILD-TYPE 62 71 33 72
'ZNF485 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.409 (Fisher's exact test), Q value = 0.75

Table S645.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF485 MUTATED 1 0 1 2 3 1 1
ZNF485 WILD-TYPE 43 41 16 31 32 30 45
'ZNF485 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.072 (Fisher's exact test), Q value = 0.32

Table S646.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF485 MUTATED 0 2 6 1 0
ZNF485 WILD-TYPE 41 38 58 74 20
'ZNF485 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.63

Table S647.  Gene #58: 'ZNF485 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF485 MUTATED 6 2 1
ZNF485 WILD-TYPE 98 53 80
'POLE MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S648.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
POLE MUTATED 2 3 1 0
POLE WILD-TYPE 11 15 12 7
'POLE MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0606 (Fisher's exact test), Q value = 0.3

Table S649.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
POLE MUTATED 3 0 2 1 0
POLE WILD-TYPE 9 10 5 6 15
'POLE MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-04 (Fisher's exact test), Q value = 0.0045

Table S650.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
POLE MUTATED 1 19 5 1
POLE WILD-TYPE 70 68 49 29

Figure S176.  Get High-res Image Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'POLE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 0.63

Table S651.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
POLE MUTATED 2 4 8
POLE WILD-TYPE 42 24 55
'POLE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.616 (Fisher's exact test), Q value = 0.92

Table S652.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
POLE MUTATED 1 4 5 4 2 4 3
POLE WILD-TYPE 23 46 26 15 20 29 21
'POLE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 0.99

Table S653.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
POLE MUTATED 6 9 5 3
POLE WILD-TYPE 62 69 26 23
'POLE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.63

Table S654.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
POLE MUTATED 5 9 7 6
POLE WILD-TYPE 59 64 29 68
'POLE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0124 (Fisher's exact test), Q value = 0.12

Table S655.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
POLE MUTATED 2 1 1 8 8 3 4
POLE WILD-TYPE 42 40 16 25 27 28 42

Figure S177.  Get High-res Image Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'POLE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 0.38

Table S656.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
POLE MUTATED 2 3 13 6 2
POLE WILD-TYPE 39 37 51 69 18
'POLE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.333 (Fisher's exact test), Q value = 0.67

Table S657.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
POLE MUTATED 15 4 7
POLE WILD-TYPE 89 51 74
'POLE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 0.95

Table S658.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
POLE MUTATED 0 4 2 4
POLE WILD-TYPE 14 43 19 26
'POLE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 0.83

Table S659.  Gene #59: 'POLE MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
POLE MUTATED 4 3 3
POLE WILD-TYPE 30 50 22
'AHCYL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 0.64

Table S660.  Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
AHCYL1 MUTATED 0 3 2 1
AHCYL1 WILD-TYPE 71 84 52 29
'AHCYL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S661.  Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
AHCYL1 MUTATED 1 0 2
AHCYL1 WILD-TYPE 43 28 61
'AHCYL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S662.  Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
AHCYL1 MUTATED 1 1 1 1 0 1 0
AHCYL1 WILD-TYPE 23 49 30 18 22 32 24
'AHCYL1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 0.99

Table S663.  Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
AHCYL1 MUTATED 1 3 1 0
AHCYL1 WILD-TYPE 67 75 30 26
'AHCYL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 0.79

Table S664.  Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
AHCYL1 MUTATED 2 1 2 1
AHCYL1 WILD-TYPE 62 72 34 73
'AHCYL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0116 (Fisher's exact test), Q value = 0.11

Table S665.  Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
AHCYL1 MUTATED 0 0 0 4 1 1 0
AHCYL1 WILD-TYPE 44 41 17 29 34 30 46

Figure S178.  Get High-res Image Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'AHCYL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.47

Table S666.  Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
AHCYL1 MUTATED 0 0 4 1 1
AHCYL1 WILD-TYPE 41 40 60 74 19
'AHCYL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.434 (Fisher's exact test), Q value = 0.77

Table S667.  Gene #60: 'AHCYL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
AHCYL1 MUTATED 4 0 2
AHCYL1 WILD-TYPE 100 55 79
'ZNF334 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S668.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZNF334 MUTATED 1 1 1 0
ZNF334 WILD-TYPE 12 17 12 7
'ZNF334 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0787 (Fisher's exact test), Q value = 0.33

Table S669.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZNF334 MUTATED 1 0 2 0 0
ZNF334 WILD-TYPE 11 10 5 7 15
'ZNF334 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0069 (Fisher's exact test), Q value = 0.077

Table S670.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF334 MUTATED 1 12 3 0
ZNF334 WILD-TYPE 70 75 51 30

Figure S179.  Get High-res Image Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF334 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 0.99

Table S671.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF334 MUTATED 4 1 6
ZNF334 WILD-TYPE 40 27 57
'ZNF334 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 0.95

Table S672.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF334 MUTATED 2 1 3 2 2 3 2
ZNF334 WILD-TYPE 22 49 28 17 20 30 22
'ZNF334 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.647 (Fisher's exact test), Q value = 0.94

Table S673.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF334 MUTATED 3 7 3 2
ZNF334 WILD-TYPE 65 71 28 24
'ZNF334 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.46

Table S674.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF334 MUTATED 3 4 6 4
ZNF334 WILD-TYPE 61 69 30 70
'ZNF334 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.013 (Fisher's exact test), Q value = 0.12

Table S675.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF334 MUTATED 1 0 2 5 5 3 1
ZNF334 WILD-TYPE 43 41 15 28 30 28 45

Figure S180.  Get High-res Image Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.357 (Fisher's exact test), Q value = 0.7

Table S676.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF334 MUTATED 2 1 8 4 1
ZNF334 WILD-TYPE 39 39 56 71 19
'ZNF334 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.605 (Fisher's exact test), Q value = 0.91

Table S677.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF334 MUTATED 9 3 4
ZNF334 WILD-TYPE 95 52 77
'ZNF334 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 0.85

Table S678.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF334 MUTATED 0 3 1 4
ZNF334 WILD-TYPE 14 44 20 26
'ZNF334 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 0.7

Table S679.  Gene #61: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF334 MUTATED 4 2 2
ZNF334 WILD-TYPE 30 51 23
'SACS MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.049 (Fisher's exact test), Q value = 0.26

Table S680.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
SACS MUTATED 6 3 1 0
SACS WILD-TYPE 7 15 12 7

Figure S181.  Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'SACS MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00147 (Fisher's exact test), Q value = 0.029

Table S681.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
SACS MUTATED 2 1 2 5 0
SACS WILD-TYPE 10 9 5 2 15

Figure S182.  Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'SACS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00129 (Fisher's exact test), Q value = 0.027

Table S682.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SACS MUTATED 1 17 5 3
SACS WILD-TYPE 70 70 49 27

Figure S183.  Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SACS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 0.86

Table S683.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SACS MUTATED 2 1 6
SACS WILD-TYPE 42 27 57
'SACS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S684.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SACS MUTATED 2 5 6 2 2 3 1
SACS WILD-TYPE 22 45 25 17 20 30 23
'SACS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S685.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SACS MUTATED 8 9 3 1
SACS WILD-TYPE 60 69 28 25
'SACS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0449 (Fisher's exact test), Q value = 0.25

Table S686.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SACS MUTATED 3 11 7 5
SACS WILD-TYPE 61 62 29 69

Figure S184.  Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SACS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00168 (Fisher's exact test), Q value = 0.032

Table S687.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SACS MUTATED 1 2 3 9 7 1 3
SACS WILD-TYPE 43 39 14 24 28 30 43

Figure S185.  Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SACS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0079 (Fisher's exact test), Q value = 0.085

Table S688.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SACS MUTATED 1 4 14 4 1
SACS WILD-TYPE 40 36 50 71 19

Figure S186.  Get High-res Image Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'SACS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.155 (Fisher's exact test), Q value = 0.47

Table S689.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SACS MUTATED 15 3 6
SACS WILD-TYPE 89 52 75
'SACS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 0.96

Table S690.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SACS MUTATED 2 3 1 2
SACS WILD-TYPE 12 44 20 28
'SACS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 0.93

Table S691.  Gene #62: 'SACS MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SACS MUTATED 2 3 3
SACS WILD-TYPE 32 50 22
'MSH4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S692.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MSH4 MUTATED 2 1 1 0
MSH4 WILD-TYPE 11 17 12 7
'MSH4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0916 (Fisher's exact test), Q value = 0.36

Table S693.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MSH4 MUTATED 1 0 2 1 0
MSH4 WILD-TYPE 11 10 5 6 15
'MSH4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00405 (Fisher's exact test), Q value = 0.055

Table S694.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MSH4 MUTATED 0 11 2 2
MSH4 WILD-TYPE 71 76 52 28

Figure S187.  Get High-res Image Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MSH4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S695.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MSH4 MUTATED 2 1 3
MSH4 WILD-TYPE 42 27 60
'MSH4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S696.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MSH4 MUTATED 1 3 4 1 1 2 1
MSH4 WILD-TYPE 23 47 27 18 21 31 23
'MSH4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.952 (Fisher's exact test), Q value = 1

Table S697.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MSH4 MUTATED 4 6 2 1
MSH4 WILD-TYPE 64 72 29 25
'MSH4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 0.77

Table S698.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MSH4 MUTATED 2 5 4 4
MSH4 WILD-TYPE 62 68 32 70
'MSH4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0282 (Fisher's exact test), Q value = 0.2

Table S699.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MSH4 MUTATED 0 1 1 5 5 1 2
MSH4 WILD-TYPE 44 40 16 28 30 30 44

Figure S188.  Get High-res Image Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MSH4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 0.77

Table S700.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MSH4 MUTATED 1 2 7 3 1
MSH4 WILD-TYPE 40 38 57 72 19
'MSH4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 0.65

Table S701.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MSH4 MUTATED 9 2 3
MSH4 WILD-TYPE 95 53 78
'MSH4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S702.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MSH4 MUTATED 0 2 1 1
MSH4 WILD-TYPE 14 45 20 29
'MSH4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.559 (Fisher's exact test), Q value = 0.87

Table S703.  Gene #63: 'MSH4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MSH4 MUTATED 2 1 1
MSH4 WILD-TYPE 32 52 24
'SLC26A8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00326 (Fisher's exact test), Q value = 0.048

Table S704.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SLC26A8 MUTATED 0 10 2 0
SLC26A8 WILD-TYPE 71 77 52 30

Figure S189.  Get High-res Image Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SLC26A8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S705.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SLC26A8 MUTATED 2 1 4
SLC26A8 WILD-TYPE 42 27 59
'SLC26A8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.63

Table S706.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SLC26A8 MUTATED 1 1 4 2 1 2 0
SLC26A8 WILD-TYPE 23 49 27 17 21 31 24
'SLC26A8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.436 (Fisher's exact test), Q value = 0.77

Table S707.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SLC26A8 MUTATED 3 5 3 0
SLC26A8 WILD-TYPE 65 73 28 26
'SLC26A8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 0.97

Table S708.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SLC26A8 MUTATED 3 5 2 2
SLC26A8 WILD-TYPE 61 68 34 72
'SLC26A8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00065 (Fisher's exact test), Q value = 0.017

Table S709.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SLC26A8 MUTATED 0 0 1 4 6 0 1
SLC26A8 WILD-TYPE 44 41 16 29 29 31 45

Figure S190.  Get High-res Image Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SLC26A8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 0.53

Table S710.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SLC26A8 MUTATED 1 1 7 2 1
SLC26A8 WILD-TYPE 40 39 57 73 19
'SLC26A8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.28 (Fisher's exact test), Q value = 0.63

Table S711.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SLC26A8 MUTATED 8 2 2
SLC26A8 WILD-TYPE 96 53 79
'SLC26A8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S712.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SLC26A8 MUTATED 0 2 1 2
SLC26A8 WILD-TYPE 14 45 20 28
'SLC26A8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 0.65

Table S713.  Gene #64: 'SLC26A8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SLC26A8 MUTATED 3 1 1
SLC26A8 WILD-TYPE 31 52 24
'KIF20B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.442 (Fisher's exact test), Q value = 0.78

Table S714.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
KIF20B MUTATED 3 1 1 0
KIF20B WILD-TYPE 10 17 12 7
'KIF20B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.045 (Fisher's exact test), Q value = 0.25

Table S715.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
KIF20B MUTATED 1 0 2 2 0
KIF20B WILD-TYPE 11 10 5 5 15

Figure S191.  Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'KIF20B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00061 (Fisher's exact test), Q value = 0.017

Table S716.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
KIF20B MUTATED 0 13 7 1
KIF20B WILD-TYPE 71 74 47 29

Figure S192.  Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'KIF20B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 0.99

Table S717.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
KIF20B MUTATED 3 2 7
KIF20B WILD-TYPE 41 26 56
'KIF20B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S718.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
KIF20B MUTATED 1 3 5 2 2 3 2
KIF20B WILD-TYPE 23 47 26 17 20 30 22
'KIF20B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.422 (Fisher's exact test), Q value = 0.76

Table S719.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
KIF20B MUTATED 4 7 5 2
KIF20B WILD-TYPE 64 71 26 24
'KIF20B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0132 (Fisher's exact test), Q value = 0.12

Table S720.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
KIF20B MUTATED 3 7 8 3
KIF20B WILD-TYPE 61 66 28 71

Figure S193.  Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'KIF20B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 2e-04 (Fisher's exact test), Q value = 0.0075

Table S721.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
KIF20B MUTATED 0 1 1 8 7 3 1
KIF20B WILD-TYPE 44 40 16 25 28 28 45

Figure S194.  Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'KIF20B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00226 (Fisher's exact test), Q value = 0.038

Table S722.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
KIF20B MUTATED 2 1 13 2 2
KIF20B WILD-TYPE 39 39 51 73 18

Figure S195.  Get High-res Image Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'KIF20B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 0.62

Table S723.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
KIF20B MUTATED 12 4 4
KIF20B WILD-TYPE 92 51 77
'KIF20B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S724.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
KIF20B MUTATED 0 3 2 3
KIF20B WILD-TYPE 14 44 19 27
'KIF20B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.318 (Fisher's exact test), Q value = 0.66

Table S725.  Gene #65: 'KIF20B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
KIF20B MUTATED 3 2 3
KIF20B WILD-TYPE 31 51 22
'RRAS2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.4

Table S726.  Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RRAS2 MUTATED 0 1 3 0
RRAS2 WILD-TYPE 71 86 51 30
'RRAS2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 0.83

Table S727.  Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RRAS2 MUTATED 1 1 0 1 0 0 1
RRAS2 WILD-TYPE 23 49 31 18 22 33 23
'RRAS2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.53

Table S728.  Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RRAS2 MUTATED 3 0 1 0
RRAS2 WILD-TYPE 65 78 30 26
'RRAS2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 0.86

Table S729.  Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RRAS2 MUTATED 1 0 1 2
RRAS2 WILD-TYPE 63 73 35 72
'RRAS2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.217 (Fisher's exact test), Q value = 0.55

Table S730.  Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RRAS2 MUTATED 0 0 1 0 1 0 2
RRAS2 WILD-TYPE 44 41 16 33 34 31 44
'RRAS2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.669 (Fisher's exact test), Q value = 0.96

Table S731.  Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RRAS2 MUTATED 0 0 1 3 0
RRAS2 WILD-TYPE 41 40 63 72 20
'RRAS2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S732.  Gene #66: 'RRAS2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RRAS2 MUTATED 1 1 2
RRAS2 WILD-TYPE 103 54 79
'CTNND1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 0.78

Table S733.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CTNND1 MUTATED 3 1 1 0
CTNND1 WILD-TYPE 10 17 12 7
'CTNND1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.4 (Fisher's exact test), Q value = 0.75

Table S734.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CTNND1 MUTATED 1 0 2 1 1
CTNND1 WILD-TYPE 11 10 5 6 14
'CTNND1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0194 (Fisher's exact test), Q value = 0.15

Table S735.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CTNND1 MUTATED 1 12 3 3
CTNND1 WILD-TYPE 70 75 51 27

Figure S196.  Get High-res Image Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CTNND1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 0.64

Table S736.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CTNND1 MUTATED 3 0 6
CTNND1 WILD-TYPE 41 28 57
'CTNND1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 0.92

Table S737.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CTNND1 MUTATED 3 5 4 1 2 2 0
CTNND1 WILD-TYPE 21 45 27 18 20 31 24
'CTNND1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 0.5

Table S738.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CTNND1 MUTATED 4 10 3 0
CTNND1 WILD-TYPE 64 68 28 26
'CTNND1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S739.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CTNND1 MUTATED 5 4 4 6
CTNND1 WILD-TYPE 59 69 32 68
'CTNND1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0401 (Fisher's exact test), Q value = 0.24

Table S740.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CTNND1 MUTATED 1 1 1 3 8 2 3
CTNND1 WILD-TYPE 43 40 16 30 27 29 43

Figure S197.  Get High-res Image Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CTNND1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 0.75

Table S741.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CTNND1 MUTATED 2 2 7 4 3
CTNND1 WILD-TYPE 39 38 57 71 17
'CTNND1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S742.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CTNND1 MUTATED 9 4 5
CTNND1 WILD-TYPE 95 51 76
'CTNND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.64

Table S743.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CTNND1 MUTATED 0 2 3 3
CTNND1 WILD-TYPE 14 45 18 27
'CTNND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 0.7

Table S744.  Gene #67: 'CTNND1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CTNND1 MUTATED 4 2 2
CTNND1 WILD-TYPE 30 51 23
'NFE2L3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.648 (Fisher's exact test), Q value = 0.95

Table S745.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NFE2L3 MUTATED 2 6 2 2
NFE2L3 WILD-TYPE 69 81 52 28
'NFE2L3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0812 (Fisher's exact test), Q value = 0.34

Table S746.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
NFE2L3 MUTATED 6 0 3
NFE2L3 WILD-TYPE 38 28 60
'NFE2L3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.711 (Fisher's exact test), Q value = 0.98

Table S747.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NFE2L3 MUTATED 1 2 1 0 1 4 1
NFE2L3 WILD-TYPE 23 48 30 19 21 29 23
'NFE2L3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.295 (Fisher's exact test), Q value = 0.64

Table S748.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NFE2L3 MUTATED 1 6 2 1
NFE2L3 WILD-TYPE 67 72 29 25
'NFE2L3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0735 (Fisher's exact test), Q value = 0.33

Table S749.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NFE2L3 MUTATED 5 1 4 2
NFE2L3 WILD-TYPE 59 72 32 72
'NFE2L3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0196 (Fisher's exact test), Q value = 0.15

Table S750.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NFE2L3 MUTATED 2 0 3 4 2 0 1
NFE2L3 WILD-TYPE 42 41 14 29 33 31 45

Figure S198.  Get High-res Image Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NFE2L3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 0.6

Table S751.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NFE2L3 MUTATED 3 0 5 2 1
NFE2L3 WILD-TYPE 38 40 59 73 19
'NFE2L3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.244 (Fisher's exact test), Q value = 0.59

Table S752.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NFE2L3 MUTATED 4 5 2
NFE2L3 WILD-TYPE 100 50 79
'NFE2L3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 0.98

Table S753.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
NFE2L3 MUTATED 1 2 1 3
NFE2L3 WILD-TYPE 13 45 20 27
'NFE2L3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0389 (Fisher's exact test), Q value = 0.23

Table S754.  Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
NFE2L3 MUTATED 5 1 1
NFE2L3 WILD-TYPE 29 52 24

Figure S199.  Get High-res Image Gene #68: 'NFE2L3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'FAM65B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0145 (Fisher's exact test), Q value = 0.13

Table S755.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FAM65B MUTATED 1 11 4 0
FAM65B WILD-TYPE 70 76 50 30

Figure S200.  Get High-res Image Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'FAM65B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 0.98

Table S756.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
FAM65B MUTATED 3 1 6
FAM65B WILD-TYPE 41 27 57
'FAM65B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.558 (Fisher's exact test), Q value = 0.87

Table S757.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FAM65B MUTATED 2 2 4 1 2 2 0
FAM65B WILD-TYPE 22 48 27 18 20 31 24
'FAM65B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 0.78

Table S758.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FAM65B MUTATED 3 5 4 1
FAM65B WILD-TYPE 65 73 27 25
'FAM65B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 0.58

Table S759.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FAM65B MUTATED 2 5 5 4
FAM65B WILD-TYPE 62 68 31 70
'FAM65B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0072 (Fisher's exact test), Q value = 0.078

Table S760.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FAM65B MUTATED 0 1 2 4 6 0 3
FAM65B WILD-TYPE 44 40 15 29 29 31 43

Figure S201.  Get High-res Image Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FAM65B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.61

Table S761.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FAM65B MUTATED 1 2 6 3 3
FAM65B WILD-TYPE 40 38 58 72 17
'FAM65B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S762.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FAM65B MUTATED 8 3 4
FAM65B WILD-TYPE 96 52 77
'FAM65B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.64

Table S763.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
FAM65B MUTATED 0 2 3 3
FAM65B WILD-TYPE 14 45 18 27
'FAM65B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.32 (Fisher's exact test), Q value = 0.66

Table S764.  Gene #69: 'FAM65B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
FAM65B MUTATED 3 2 3
FAM65B WILD-TYPE 31 51 22
'RNF43 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S765.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
RNF43 MUTATED 3 1 0 0
RNF43 WILD-TYPE 10 17 13 7
'RNF43 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00937 (Fisher's exact test), Q value = 0.095

Table S766.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
RNF43 MUTATED 1 0 0 3 0
RNF43 WILD-TYPE 11 10 7 4 15

Figure S202.  Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'RNF43 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.044 (Fisher's exact test), Q value = 0.25

Table S767.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RNF43 MUTATED 0 7 4 1
RNF43 WILD-TYPE 71 80 50 29

Figure S203.  Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RNF43 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S768.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RNF43 MUTATED 2 0 3
RNF43 WILD-TYPE 42 28 60
'RNF43 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.565 (Fisher's exact test), Q value = 0.87

Table S769.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RNF43 MUTATED 2 3 3 2 0 2 0
RNF43 WILD-TYPE 22 47 28 17 22 31 24
'RNF43 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.495 (Fisher's exact test), Q value = 0.83

Table S770.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RNF43 MUTATED 6 5 1 0
RNF43 WILD-TYPE 62 73 30 26
'RNF43 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0337 (Fisher's exact test), Q value = 0.22

Table S771.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RNF43 MUTATED 1 6 4 1
RNF43 WILD-TYPE 63 67 32 73

Figure S204.  Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'RNF43 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-04 (Fisher's exact test), Q value = 0.0045

Table S772.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RNF43 MUTATED 0 1 1 8 1 1 0
RNF43 WILD-TYPE 44 40 16 25 34 30 46

Figure S205.  Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RNF43 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0392 (Fisher's exact test), Q value = 0.23

Table S773.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RNF43 MUTATED 1 1 8 1 1
RNF43 WILD-TYPE 40 39 56 74 19

Figure S206.  Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'RNF43 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0209 (Fisher's exact test), Q value = 0.16

Table S774.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RNF43 MUTATED 10 1 1
RNF43 WILD-TYPE 94 54 80

Figure S207.  Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RNF43 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.072 (Fisher's exact test), Q value = 0.32

Table S775.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RNF43 MUTATED 0 0 1 3
RNF43 WILD-TYPE 14 47 20 27
'RNF43 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.022 (Fisher's exact test), Q value = 0.16

Table S776.  Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RNF43 MUTATED 1 0 3
RNF43 WILD-TYPE 33 53 22

Figure S208.  Get High-res Image Gene #70: 'RNF43 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MRPL47 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S777.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MRPL47 MUTATED 1 2 0 0
MRPL47 WILD-TYPE 12 16 13 7
'MRPL47 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.535 (Fisher's exact test), Q value = 0.85

Table S778.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MRPL47 MUTATED 1 1 1 0 0
MRPL47 WILD-TYPE 11 9 6 7 15
'MRPL47 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 0.5

Table S779.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MRPL47 MUTATED 1 5 0 0
MRPL47 WILD-TYPE 70 82 54 30
'MRPL47 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S780.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MRPL47 MUTATED 1 0 2
MRPL47 WILD-TYPE 43 28 61
'MRPL47 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 0.64

Table S781.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MRPL47 MUTATED 1 0 0 1 1 2 1
MRPL47 WILD-TYPE 23 50 31 18 21 31 23
'MRPL47 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 0.83

Table S782.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MRPL47 MUTATED 1 4 0 1
MRPL47 WILD-TYPE 67 74 31 25
'MRPL47 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00618 (Fisher's exact test), Q value = 0.071

Table S783.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MRPL47 MUTATED 1 0 4 1
MRPL47 WILD-TYPE 63 73 32 73

Figure S209.  Get High-res Image Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MRPL47 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0728 (Fisher's exact test), Q value = 0.33

Table S784.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MRPL47 MUTATED 1 0 1 3 1 0 0
MRPL47 WILD-TYPE 43 41 16 30 34 31 46
'MRPL47 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 0.81

Table S785.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MRPL47 MUTATED 0 0 3 1 0
MRPL47 WILD-TYPE 41 40 61 74 20
'MRPL47 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S786.  Gene #71: 'MRPL47 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MRPL47 MUTATED 2 1 1
MRPL47 WILD-TYPE 102 54 80
'TIGD4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S787.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
TIGD4 MUTATED 1 2 1 0
TIGD4 WILD-TYPE 12 16 12 7
'TIGD4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.583 (Fisher's exact test), Q value = 0.89

Table S788.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
TIGD4 MUTATED 2 0 1 0 1
TIGD4 WILD-TYPE 10 10 6 7 14
'TIGD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0195 (Fisher's exact test), Q value = 0.15

Table S789.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TIGD4 MUTATED 1 10 2 0
TIGD4 WILD-TYPE 70 77 52 30

Figure S210.  Get High-res Image Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TIGD4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S790.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TIGD4 MUTATED 2 1 3
TIGD4 WILD-TYPE 42 27 60
'TIGD4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.53

Table S791.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TIGD4 MUTATED 1 1 4 1 3 2 0
TIGD4 WILD-TYPE 23 49 27 18 19 31 24
'TIGD4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.08 (Fisher's exact test), Q value = 0.33

Table S792.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TIGD4 MUTATED 3 4 5 0
TIGD4 WILD-TYPE 65 74 26 26
'TIGD4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 0.56

Table S793.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TIGD4 MUTATED 2 5 4 2
TIGD4 WILD-TYPE 62 68 32 72
'TIGD4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00148 (Fisher's exact test), Q value = 0.029

Table S794.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TIGD4 MUTATED 0 0 1 4 6 0 2
TIGD4 WILD-TYPE 44 41 16 29 29 31 44

Figure S211.  Get High-res Image Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TIGD4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.53

Table S795.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TIGD4 MUTATED 1 1 7 2 1
TIGD4 WILD-TYPE 40 39 57 73 19
'TIGD4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.277 (Fisher's exact test), Q value = 0.63

Table S796.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TIGD4 MUTATED 8 2 2
TIGD4 WILD-TYPE 96 53 79
'TIGD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S797.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
TIGD4 MUTATED 0 2 1 2
TIGD4 WILD-TYPE 14 45 20 28
'TIGD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.433 (Fisher's exact test), Q value = 0.77

Table S798.  Gene #72: 'TIGD4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
TIGD4 MUTATED 2 1 2
TIGD4 WILD-TYPE 32 52 23
'FILIP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 0.87

Table S799.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
FILIP1 MUTATED 2 2 0 0
FILIP1 WILD-TYPE 11 16 13 7
'FILIP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.246 (Fisher's exact test), Q value = 0.6

Table S800.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
FILIP1 MUTATED 2 0 1 1 0
FILIP1 WILD-TYPE 10 10 6 6 15
'FILIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 0.48

Table S801.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FILIP1 MUTATED 2 10 3 1
FILIP1 WILD-TYPE 69 77 51 29
'FILIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.714 (Fisher's exact test), Q value = 0.98

Table S802.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
FILIP1 MUTATED 2 1 5
FILIP1 WILD-TYPE 42 27 58
'FILIP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.287 (Fisher's exact test), Q value = 0.63

Table S803.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FILIP1 MUTATED 0 2 5 2 2 2 1
FILIP1 WILD-TYPE 24 48 26 17 20 31 23
'FILIP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.41

Table S804.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FILIP1 MUTATED 2 6 5 1
FILIP1 WILD-TYPE 66 72 26 25
'FILIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 0.46

Table S805.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FILIP1 MUTATED 2 6 5 3
FILIP1 WILD-TYPE 62 67 31 71
'FILIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00224 (Fisher's exact test), Q value = 0.038

Table S806.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FILIP1 MUTATED 0 0 1 4 7 1 3
FILIP1 WILD-TYPE 44 41 16 29 28 30 43

Figure S212.  Get High-res Image Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FILIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 0.98

Table S807.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FILIP1 MUTATED 3 1 6 4 1
FILIP1 WILD-TYPE 38 39 58 71 19
'FILIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.454 (Fisher's exact test), Q value = 0.79

Table S808.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FILIP1 MUTATED 9 2 4
FILIP1 WILD-TYPE 95 53 77
'FILIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S809.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
FILIP1 MUTATED 0 2 1 2
FILIP1 WILD-TYPE 14 45 20 28
'FILIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S810.  Gene #73: 'FILIP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
FILIP1 MUTATED 2 2 1
FILIP1 WILD-TYPE 32 51 24
'SLC1A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 0.48

Table S811.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SLC1A3 MUTATED 3 8 1 0
SLC1A3 WILD-TYPE 68 79 53 30
'SLC1A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S812.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SLC1A3 MUTATED 3 1 2
SLC1A3 WILD-TYPE 41 27 61
'SLC1A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 0.68

Table S813.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SLC1A3 MUTATED 1 1 3 2 2 1 0
SLC1A3 WILD-TYPE 23 49 28 17 20 32 24
'SLC1A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.74

Table S814.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SLC1A3 MUTATED 2 6 2 0
SLC1A3 WILD-TYPE 66 72 29 26
'SLC1A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.356 (Fisher's exact test), Q value = 0.7

Table S815.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SLC1A3 MUTATED 6 2 1 3
SLC1A3 WILD-TYPE 58 71 35 71
'SLC1A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0308 (Fisher's exact test), Q value = 0.21

Table S816.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SLC1A3 MUTATED 1 0 2 2 5 0 2
SLC1A3 WILD-TYPE 43 41 15 31 30 31 44

Figure S213.  Get High-res Image Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SLC1A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S817.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SLC1A3 MUTATED 1 2 5 3 1
SLC1A3 WILD-TYPE 40 38 59 72 19
'SLC1A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.644 (Fisher's exact test), Q value = 0.94

Table S818.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SLC1A3 MUTATED 5 4 3
SLC1A3 WILD-TYPE 99 51 78
'SLC1A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 0.91

Table S819.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SLC1A3 MUTATED 0 2 1 3
SLC1A3 WILD-TYPE 14 45 20 27
'SLC1A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.1 (Fisher's exact test), Q value = 0.37

Table S820.  Gene #74: 'SLC1A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SLC1A3 MUTATED 4 1 1
SLC1A3 WILD-TYPE 30 52 24
'UFSP2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.554 (Fisher's exact test), Q value = 0.87

Table S821.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
UFSP2 MUTATED 2 2 0 0
UFSP2 WILD-TYPE 11 16 13 7
'UFSP2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 0.6

Table S822.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
UFSP2 MUTATED 2 0 1 1 0
UFSP2 WILD-TYPE 10 10 6 6 15
'UFSP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0324 (Fisher's exact test), Q value = 0.21

Table S823.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
UFSP2 MUTATED 0 8 2 1
UFSP2 WILD-TYPE 71 79 52 29

Figure S214.  Get High-res Image Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'UFSP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 0.75

Table S824.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
UFSP2 MUTATED 3 0 3
UFSP2 WILD-TYPE 41 28 60
'UFSP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S825.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
UFSP2 MUTATED 2 2 3 1 1 1 1
UFSP2 WILD-TYPE 22 48 28 18 21 32 23
'UFSP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.664 (Fisher's exact test), Q value = 0.95

Table S826.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
UFSP2 MUTATED 2 6 2 1
UFSP2 WILD-TYPE 66 72 29 25
'UFSP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0172 (Fisher's exact test), Q value = 0.14

Table S827.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
UFSP2 MUTATED 1 4 5 1
UFSP2 WILD-TYPE 63 69 31 73

Figure S215.  Get High-res Image Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'UFSP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 9e-05 (Fisher's exact test), Q value = 0.0042

Table S828.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
UFSP2 MUTATED 0 0 1 6 4 0 0
UFSP2 WILD-TYPE 44 41 16 27 31 31 46

Figure S216.  Get High-res Image Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'UFSP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0332 (Fisher's exact test), Q value = 0.22

Table S829.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
UFSP2 MUTATED 1 0 7 1 1
UFSP2 WILD-TYPE 40 40 57 74 19

Figure S217.  Get High-res Image Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'UFSP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.53

Table S830.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
UFSP2 MUTATED 7 2 1
UFSP2 WILD-TYPE 97 53 80
'UFSP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 0.76

Table S831.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
UFSP2 MUTATED 0 1 2 1
UFSP2 WILD-TYPE 14 46 19 29
'UFSP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0904 (Fisher's exact test), Q value = 0.36

Table S832.  Gene #75: 'UFSP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
UFSP2 MUTATED 2 0 2
UFSP2 WILD-TYPE 32 53 23
'WBP4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0797 (Fisher's exact test), Q value = 0.33

Table S833.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
WBP4 MUTATED 0 6 1 1
WBP4 WILD-TYPE 71 81 53 29
'WBP4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 0.64

Table S834.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
WBP4 MUTATED 1 0 5
WBP4 WILD-TYPE 43 28 58
'WBP4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0519 (Fisher's exact test), Q value = 0.27

Table S835.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
WBP4 MUTATED 2 0 3 0 2 0 1
WBP4 WILD-TYPE 22 50 28 19 20 33 23
'WBP4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S836.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
WBP4 MUTATED 2 3 2 1
WBP4 WILD-TYPE 66 75 29 25
'WBP4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.212 (Fisher's exact test), Q value = 0.54

Table S837.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
WBP4 MUTATED 1 3 3 1
WBP4 WILD-TYPE 63 70 33 73
'WBP4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00077 (Fisher's exact test), Q value = 0.019

Table S838.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
WBP4 MUTATED 0 0 0 4 4 0 0
WBP4 WILD-TYPE 44 41 17 29 31 31 46

Figure S218.  Get High-res Image Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'WBP4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 0.98

Table S839.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
WBP4 MUTATED 1 1 3 1 1
WBP4 WILD-TYPE 40 39 61 74 19
'WBP4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0929 (Fisher's exact test), Q value = 0.36

Table S840.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
WBP4 MUTATED 6 0 1
WBP4 WILD-TYPE 98 55 80
'WBP4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S841.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
WBP4 MUTATED 0 1 1 1
WBP4 WILD-TYPE 14 46 20 29
'WBP4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0806 (Fisher's exact test), Q value = 0.33

Table S842.  Gene #76: 'WBP4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
WBP4 MUTATED 1 0 2
WBP4 WILD-TYPE 33 53 23
'TRIM59 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.055 (Fisher's exact test), Q value = 0.28

Table S843.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TRIM59 MUTATED 0 6 1 2
TRIM59 WILD-TYPE 71 81 53 28
'TRIM59 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S844.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TRIM59 MUTATED 1 1 3
TRIM59 WILD-TYPE 43 27 60
'TRIM59 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.717 (Fisher's exact test), Q value = 0.99

Table S845.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TRIM59 MUTATED 1 3 2 1 1 0 0
TRIM59 WILD-TYPE 23 47 29 18 21 33 24
'TRIM59 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S846.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TRIM59 MUTATED 3 4 1 0
TRIM59 WILD-TYPE 65 74 30 26
'TRIM59 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 0.81

Table S847.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TRIM59 MUTATED 2 1 2 4
TRIM59 WILD-TYPE 62 72 34 70
'TRIM59 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0765 (Fisher's exact test), Q value = 0.33

Table S848.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TRIM59 MUTATED 0 0 0 3 3 2 1
TRIM59 WILD-TYPE 44 41 17 30 32 29 45
'TRIM59 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.693 (Fisher's exact test), Q value = 0.97

Table S849.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TRIM59 MUTATED 0 1 3 3 1
TRIM59 WILD-TYPE 41 39 61 72 19
'TRIM59 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S850.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TRIM59 MUTATED 4 1 3
TRIM59 WILD-TYPE 100 54 78
'TRIM59 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 0.76

Table S851.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
TRIM59 MUTATED 0 1 2 1
TRIM59 WILD-TYPE 14 46 19 29
'TRIM59 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.022 (Fisher's exact test), Q value = 0.16

Table S852.  Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
TRIM59 MUTATED 1 0 3
TRIM59 WILD-TYPE 33 53 22

Figure S219.  Get High-res Image Gene #77: 'TRIM59 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RSBN1L MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.52

Table S853.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
RSBN1L MUTATED 3 1 0 0
RSBN1L WILD-TYPE 10 17 13 7
'RSBN1L MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0915 (Fisher's exact test), Q value = 0.36

Table S854.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
RSBN1L MUTATED 1 0 1 2 0
RSBN1L WILD-TYPE 11 10 6 5 15
'RSBN1L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 0.62

Table S855.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RSBN1L MUTATED 1 7 3 1
RSBN1L WILD-TYPE 70 80 51 29
'RSBN1L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S856.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RSBN1L MUTATED 2 0 2
RSBN1L WILD-TYPE 42 28 61
'RSBN1L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S857.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RSBN1L MUTATED 1 2 2 2 2 2 0
RSBN1L WILD-TYPE 23 48 29 17 20 31 24
'RSBN1L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 0.54

Table S858.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RSBN1L MUTATED 3 4 4 0
RSBN1L WILD-TYPE 65 74 27 26
'RSBN1L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.255 (Fisher's exact test), Q value = 0.61

Table S859.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RSBN1L MUTATED 2 4 4 2
RSBN1L WILD-TYPE 62 69 32 72
'RSBN1L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00411 (Fisher's exact test), Q value = 0.056

Table S860.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RSBN1L MUTATED 0 0 1 3 6 1 1
RSBN1L WILD-TYPE 44 41 16 30 29 30 45

Figure S220.  Get High-res Image Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RSBN1L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0824 (Fisher's exact test), Q value = 0.34

Table S861.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RSBN1L MUTATED 2 0 7 2 0
RSBN1L WILD-TYPE 39 40 57 73 20
'RSBN1L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.419 (Fisher's exact test), Q value = 0.76

Table S862.  Gene #78: 'RSBN1L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RSBN1L MUTATED 7 2 2
RSBN1L WILD-TYPE 97 53 79
'SERHL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 0.58

Table S863.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SERHL2 MUTATED 0 4 1 1
SERHL2 WILD-TYPE 71 83 53 29
'SERHL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S864.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SERHL2 MUTATED 2 0 2
SERHL2 WILD-TYPE 42 28 61
'SERHL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S865.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SERHL2 MUTATED 0 2 1 0 1 2 0
SERHL2 WILD-TYPE 24 48 30 19 21 31 24
'SERHL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S866.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SERHL2 MUTATED 2 3 1 0
SERHL2 WILD-TYPE 66 75 30 26
'SERHL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 0.66

Table S867.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SERHL2 MUTATED 0 2 2 2
SERHL2 WILD-TYPE 64 71 34 72
'SERHL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.345 (Fisher's exact test), Q value = 0.69

Table S868.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SERHL2 MUTATED 0 1 1 0 2 0 2
SERHL2 WILD-TYPE 44 40 16 33 33 31 44
'SERHL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S869.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SERHL2 MUTATED 0 1 1 3 0
SERHL2 WILD-TYPE 41 39 63 72 20
'SERHL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 0.78

Table S870.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SERHL2 MUTATED 1 1 3
SERHL2 WILD-TYPE 103 54 78
'SERHL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.371 (Fisher's exact test), Q value = 0.71

Table S871.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SERHL2 MUTATED 1 1 0 2
SERHL2 WILD-TYPE 13 46 21 28
'SERHL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 0.96

Table S872.  Gene #79: 'SERHL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SERHL2 MUTATED 2 2 0
SERHL2 WILD-TYPE 32 51 25
'OR52I2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S873.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
OR52I2 MUTATED 1 2 0 0
OR52I2 WILD-TYPE 12 16 13 7
'OR52I2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.531 (Fisher's exact test), Q value = 0.85

Table S874.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
OR52I2 MUTATED 1 1 0 1 0
OR52I2 WILD-TYPE 11 9 7 6 15
'OR52I2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.469 (Fisher's exact test), Q value = 0.81

Table S875.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
OR52I2 MUTATED 1 5 1 1
OR52I2 WILD-TYPE 70 82 53 29
'OR52I2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 0.45

Table S876.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
OR52I2 MUTATED 0 0 4
OR52I2 WILD-TYPE 44 28 59
'OR52I2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 0.64

Table S877.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
OR52I2 MUTATED 1 1 0 1 2 0 1
OR52I2 WILD-TYPE 23 49 31 18 20 33 23
'OR52I2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S878.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
OR52I2 MUTATED 1 3 1 1
OR52I2 WILD-TYPE 67 75 30 25
'OR52I2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S879.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
OR52I2 MUTATED 3 2 1 2
OR52I2 WILD-TYPE 61 71 35 72
'OR52I2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0979 (Fisher's exact test), Q value = 0.37

Table S880.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
OR52I2 MUTATED 1 0 0 2 4 0 1
OR52I2 WILD-TYPE 43 41 17 31 31 31 45
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.46

Table S881.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
OR52I2 MUTATED 0 0 5 2 0
OR52I2 WILD-TYPE 41 40 59 73 20
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S882.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
OR52I2 MUTATED 4 1 2
OR52I2 WILD-TYPE 100 54 79
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S883.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
OR52I2 MUTATED 0 2 0 1
OR52I2 WILD-TYPE 14 45 21 29
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 0.78

Table S884.  Gene #80: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
OR52I2 MUTATED 2 1 0
OR52I2 WILD-TYPE 32 52 25
'SGK1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 0.83

Table S885.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
SGK1 MUTATED 2 1 0 0
SGK1 WILD-TYPE 11 17 13 7
'SGK1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S886.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
SGK1 MUTATED 1 0 1 1 0
SGK1 WILD-TYPE 11 10 6 6 15
'SGK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 0.66

Table S887.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SGK1 MUTATED 2 8 2 1
SGK1 WILD-TYPE 69 79 52 29
'SGK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 0.96

Table S888.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SGK1 MUTATED 1 0 3
SGK1 WILD-TYPE 43 28 60
'SGK1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.724 (Fisher's exact test), Q value = 0.99

Table S889.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SGK1 MUTATED 2 1 3 1 1 3 2
SGK1 WILD-TYPE 22 49 28 18 21 30 22
'SGK1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S890.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SGK1 MUTATED 5 5 2 1
SGK1 WILD-TYPE 63 73 29 25
'SGK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0492 (Fisher's exact test), Q value = 0.26

Table S891.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SGK1 MUTATED 1 5 5 2
SGK1 WILD-TYPE 63 68 31 72

Figure S221.  Get High-res Image Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SGK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.347 (Fisher's exact test), Q value = 0.69

Table S892.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SGK1 MUTATED 0 3 2 2 3 1 2
SGK1 WILD-TYPE 44 38 15 31 32 30 44
'SGK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.48

Table S893.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SGK1 MUTATED 1 3 6 1 1
SGK1 WILD-TYPE 40 37 58 74 19
'SGK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0638 (Fisher's exact test), Q value = 0.31

Table S894.  Gene #81: 'SGK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SGK1 MUTATED 9 2 1
SGK1 WILD-TYPE 95 53 80
'LNX2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.504 (Fisher's exact test), Q value = 0.83

Table S895.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
LNX2 MUTATED 2 1 0 0
LNX2 WILD-TYPE 11 17 13 7
'LNX2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.284 (Fisher's exact test), Q value = 0.63

Table S896.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
LNX2 MUTATED 1 0 1 1 0
LNX2 WILD-TYPE 11 10 6 6 15
'LNX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0311 (Fisher's exact test), Q value = 0.21

Table S897.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
LNX2 MUTATED 0 8 4 2
LNX2 WILD-TYPE 71 79 50 28

Figure S222.  Get High-res Image Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'LNX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.48

Table S898.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
LNX2 MUTATED 1 0 6
LNX2 WILD-TYPE 43 28 57
'LNX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S899.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
LNX2 MUTATED 1 3 3 2 1 1 1
LNX2 WILD-TYPE 23 47 28 17 21 32 23
'LNX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.378 (Fisher's exact test), Q value = 0.72

Table S900.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
LNX2 MUTATED 3 4 4 1
LNX2 WILD-TYPE 65 74 27 25
'LNX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.049 (Fisher's exact test), Q value = 0.26

Table S901.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
LNX2 MUTATED 2 7 4 1
LNX2 WILD-TYPE 62 66 32 73

Figure S223.  Get High-res Image Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'LNX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00281 (Fisher's exact test), Q value = 0.043

Table S902.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
LNX2 MUTATED 0 1 0 5 6 1 1
LNX2 WILD-TYPE 44 40 17 28 29 30 45

Figure S224.  Get High-res Image Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'LNX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.048 (Fisher's exact test), Q value = 0.26

Table S903.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
LNX2 MUTATED 1 1 9 2 1
LNX2 WILD-TYPE 40 39 55 73 19

Figure S225.  Get High-res Image Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'LNX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00462 (Fisher's exact test), Q value = 0.06

Table S904.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
LNX2 MUTATED 12 1 1
LNX2 WILD-TYPE 92 54 80

Figure S226.  Get High-res Image Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'LNX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 0.92

Table S905.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
LNX2 MUTATED 0 1 0 2
LNX2 WILD-TYPE 14 46 21 28
'LNX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S906.  Gene #82: 'LNX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
LNX2 MUTATED 1 1 1
LNX2 WILD-TYPE 33 52 24
'ALPK2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0483 (Fisher's exact test), Q value = 0.26

Table S907.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ALPK2 MUTATED 4 1 0 0
ALPK2 WILD-TYPE 9 17 13 7

Figure S227.  Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'ALPK2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0146 (Fisher's exact test), Q value = 0.13

Table S908.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ALPK2 MUTATED 1 0 1 3 0
ALPK2 WILD-TYPE 11 10 6 4 15

Figure S228.  Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'ALPK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00109 (Fisher's exact test), Q value = 0.024

Table S909.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ALPK2 MUTATED 1 14 1 3
ALPK2 WILD-TYPE 70 73 53 27

Figure S229.  Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ALPK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S910.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ALPK2 MUTATED 3 1 5
ALPK2 WILD-TYPE 41 27 58
'ALPK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S911.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ALPK2 MUTATED 2 4 5 1 2 2 1
ALPK2 WILD-TYPE 22 46 26 18 20 31 23
'ALPK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 0.7

Table S912.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ALPK2 MUTATED 6 5 5 1
ALPK2 WILD-TYPE 62 73 26 25
'ALPK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.42

Table S913.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ALPK2 MUTATED 2 8 5 4
ALPK2 WILD-TYPE 62 65 31 70
'ALPK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00335 (Fisher's exact test), Q value = 0.048

Table S914.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ALPK2 MUTATED 0 2 3 7 4 2 1
ALPK2 WILD-TYPE 44 39 14 26 31 29 45

Figure S230.  Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ALPK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0463 (Fisher's exact test), Q value = 0.26

Table S915.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ALPK2 MUTATED 0 2 10 6 1
ALPK2 WILD-TYPE 41 38 54 69 19

Figure S231.  Get High-res Image Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ALPK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.716 (Fisher's exact test), Q value = 0.99

Table S916.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ALPK2 MUTATED 10 4 5
ALPK2 WILD-TYPE 94 51 76
'ALPK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S917.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ALPK2 MUTATED 1 3 1 3
ALPK2 WILD-TYPE 13 44 20 27
'ALPK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.46

Table S918.  Gene #83: 'ALPK2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ALPK2 MUTATED 5 2 1
ALPK2 WILD-TYPE 29 51 24
'REV3L MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S919.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
REV3L MUTATED 2 1 0 0
REV3L WILD-TYPE 11 17 13 7
'REV3L MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S920.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
REV3L MUTATED 1 0 1 1 0
REV3L WILD-TYPE 11 10 6 6 15
'REV3L MUTATION STATUS' versus 'CN_CNMF'

P value = 7e-04 (Fisher's exact test), Q value = 0.018

Table S921.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
REV3L MUTATED 0 14 3 3
REV3L WILD-TYPE 71 73 51 27

Figure S232.  Get High-res Image Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'REV3L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 0.94

Table S922.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
REV3L MUTATED 3 2 8
REV3L WILD-TYPE 41 26 55
'REV3L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 0.84

Table S923.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
REV3L MUTATED 3 2 4 3 2 2 1
REV3L WILD-TYPE 21 48 27 16 20 31 23
'REV3L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.654 (Fisher's exact test), Q value = 0.95

Table S924.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
REV3L MUTATED 5 7 4 1
REV3L WILD-TYPE 63 71 27 25
'REV3L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0383 (Fisher's exact test), Q value = 0.23

Table S925.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
REV3L MUTATED 2 7 7 4
REV3L WILD-TYPE 62 66 29 70

Figure S233.  Get High-res Image Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'REV3L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00106 (Fisher's exact test), Q value = 0.024

Table S926.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
REV3L MUTATED 0 1 1 8 6 1 3
REV3L WILD-TYPE 44 40 16 25 29 30 43

Figure S234.  Get High-res Image Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'REV3L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 0.55

Table S927.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
REV3L MUTATED 1 3 9 4 2
REV3L WILD-TYPE 40 37 55 71 18
'REV3L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0957 (Fisher's exact test), Q value = 0.36

Table S928.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
REV3L MUTATED 13 2 4
REV3L WILD-TYPE 91 53 77
'REV3L MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 0.95

Table S929.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
REV3L MUTATED 0 4 2 4
REV3L WILD-TYPE 14 43 19 26
'REV3L MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.157 (Fisher's exact test), Q value = 0.47

Table S930.  Gene #84: 'REV3L MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
REV3L MUTATED 4 2 4
REV3L WILD-TYPE 30 51 21
'CAB39L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.097 (Fisher's exact test), Q value = 0.36

Table S931.  Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CAB39L MUTATED 0 5 3 0
CAB39L WILD-TYPE 71 82 51 30
'CAB39L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.502 (Fisher's exact test), Q value = 0.83

Table S932.  Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CAB39L MUTATED 0 3 2 0 1 0 0
CAB39L WILD-TYPE 24 47 29 19 21 33 24
'CAB39L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.46

Table S933.  Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CAB39L MUTATED 2 1 3 0
CAB39L WILD-TYPE 66 77 28 26
'CAB39L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S934.  Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CAB39L MUTATED 1 5 0 2
CAB39L WILD-TYPE 63 68 36 72
'CAB39L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0182 (Fisher's exact test), Q value = 0.15

Table S935.  Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CAB39L MUTATED 0 3 0 0 4 1 0
CAB39L WILD-TYPE 44 38 17 33 31 30 46

Figure S235.  Get High-res Image Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CAB39L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.63

Table S936.  Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CAB39L MUTATED 0 1 5 2 0
CAB39L WILD-TYPE 41 39 59 73 20
'CAB39L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0212 (Fisher's exact test), Q value = 0.16

Table S937.  Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CAB39L MUTATED 7 1 0
CAB39L WILD-TYPE 97 54 81

Figure S236.  Get High-res Image Gene #85: 'CAB39L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ERBB3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S938.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ERBB3 MUTATED 4 8 4 1
ERBB3 WILD-TYPE 67 79 50 29
'ERBB3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 0.87

Table S939.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ERBB3 MUTATED 2 3 6
ERBB3 WILD-TYPE 42 25 57
'ERBB3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S940.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ERBB3 MUTATED 2 4 2 0 1 2 3
ERBB3 WILD-TYPE 22 46 29 19 21 31 21
'ERBB3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.038 (Fisher's exact test), Q value = 0.23

Table S941.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ERBB3 MUTATED 5 2 2 5
ERBB3 WILD-TYPE 63 76 29 21

Figure S237.  Get High-res Image Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'ERBB3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 0.87

Table S942.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ERBB3 MUTATED 3 6 4 4
ERBB3 WILD-TYPE 61 67 32 70
'ERBB3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.274 (Fisher's exact test), Q value = 0.63

Table S943.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ERBB3 MUTATED 2 2 1 5 4 0 3
ERBB3 WILD-TYPE 42 39 16 28 31 31 43
'ERBB3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 0.53

Table S944.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ERBB3 MUTATED 1 1 7 5 3
ERBB3 WILD-TYPE 40 39 57 70 17
'ERBB3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.949 (Fisher's exact test), Q value = 1

Table S945.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ERBB3 MUTATED 8 4 5
ERBB3 WILD-TYPE 96 51 76
'ERBB3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 0.86

Table S946.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ERBB3 MUTATED 0 2 2 3
ERBB3 WILD-TYPE 14 45 19 27
'ERBB3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S947.  Gene #86: 'ERBB3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ERBB3 MUTATED 2 3 2
ERBB3 WILD-TYPE 32 50 23
'INPP4B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 0.79

Table S948.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
INPP4B MUTATED 1 3 0 0
INPP4B WILD-TYPE 12 15 13 7
'INPP4B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0783 (Fisher's exact test), Q value = 0.33

Table S949.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
INPP4B MUTATED 3 0 1 0 0
INPP4B WILD-TYPE 9 10 6 7 15
'INPP4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00173 (Fisher's exact test), Q value = 0.032

Table S950.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
INPP4B MUTATED 0 10 1 0
INPP4B WILD-TYPE 71 77 53 30

Figure S238.  Get High-res Image Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'INPP4B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 0.68

Table S951.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
INPP4B MUTATED 1 2 2 2 2 0 0
INPP4B WILD-TYPE 23 48 29 17 20 33 24
'INPP4B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.389 (Fisher's exact test), Q value = 0.73

Table S952.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
INPP4B MUTATED 3 3 3 0
INPP4B WILD-TYPE 65 75 28 26
'INPP4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S953.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
INPP4B MUTATED 2 4 2 4
INPP4B WILD-TYPE 62 69 34 70
'INPP4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00246 (Fisher's exact test), Q value = 0.039

Table S954.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
INPP4B MUTATED 0 0 0 3 6 0 3
INPP4B WILD-TYPE 44 41 17 30 29 31 43

Figure S239.  Get High-res Image Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'INPP4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.386 (Fisher's exact test), Q value = 0.73

Table S955.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
INPP4B MUTATED 0 2 5 4 0
INPP4B WILD-TYPE 41 38 59 71 20
'INPP4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.668 (Fisher's exact test), Q value = 0.96

Table S956.  Gene #87: 'INPP4B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
INPP4B MUTATED 6 1 4
INPP4B WILD-TYPE 98 54 77
'C1ORF100 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.504 (Fisher's exact test), Q value = 0.83

Table S957.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
C1ORF100 MUTATED 2 1 0 0
C1ORF100 WILD-TYPE 11 17 13 7
'C1ORF100 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S958.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
C1ORF100 MUTATED 1 0 1 1 0
C1ORF100 WILD-TYPE 11 10 6 6 15
'C1ORF100 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 0.83

Table S959.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
C1ORF100 MUTATED 1 4 2 2
C1ORF100 WILD-TYPE 70 83 52 28
'C1ORF100 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S960.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
C1ORF100 MUTATED 1 1 1
C1ORF100 WILD-TYPE 43 27 62
'C1ORF100 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S961.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
C1ORF100 MUTATED 0 3 2 1 0 1 0
C1ORF100 WILD-TYPE 24 47 29 18 22 32 24
'C1ORF100 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.32 (Fisher's exact test), Q value = 0.66

Table S962.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
C1ORF100 MUTATED 1 5 1 0
C1ORF100 WILD-TYPE 67 73 30 26
'C1ORF100 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.203 (Fisher's exact test), Q value = 0.53

Table S963.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
C1ORF100 MUTATED 1 5 2 1
C1ORF100 WILD-TYPE 63 68 34 73
'C1ORF100 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0139 (Fisher's exact test), Q value = 0.13

Table S964.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
C1ORF100 MUTATED 0 0 1 4 3 0 1
C1ORF100 WILD-TYPE 44 41 16 29 32 31 45

Figure S240.  Get High-res Image Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'C1ORF100 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.154 (Fisher's exact test), Q value = 0.47

Table S965.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
C1ORF100 MUTATED 1 1 6 1 0
C1ORF100 WILD-TYPE 40 39 58 74 20
'C1ORF100 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.129 (Fisher's exact test), Q value = 0.43

Table S966.  Gene #88: 'C1ORF100 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
C1ORF100 MUTATED 7 1 1
C1ORF100 WILD-TYPE 97 54 80
'IL20 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S967.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
IL20 MUTATED 3 1 0 0
IL20 WILD-TYPE 10 17 13 7
'IL20 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0913 (Fisher's exact test), Q value = 0.36

Table S968.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
IL20 MUTATED 1 0 1 2 0
IL20 WILD-TYPE 11 10 6 5 15
'IL20 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.61

Table S969.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
IL20 MUTATED 0 4 2 1
IL20 WILD-TYPE 71 83 52 29
'IL20 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S970.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
IL20 MUTATED 1 1 1 1 1 1 0
IL20 WILD-TYPE 23 49 30 18 21 32 24
'IL20 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 0.85

Table S971.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
IL20 MUTATED 1 4 1 0
IL20 WILD-TYPE 67 74 30 26
'IL20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.53

Table S972.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
IL20 MUTATED 2 1 3 1
IL20 WILD-TYPE 62 72 33 73
'IL20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0182 (Fisher's exact test), Q value = 0.15

Table S973.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
IL20 MUTATED 0 1 0 4 2 0 0
IL20 WILD-TYPE 44 40 17 29 33 31 46

Figure S241.  Get High-res Image Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'IL20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.47

Table S974.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
IL20 MUTATED 0 0 4 1 1
IL20 WILD-TYPE 41 40 60 74 19
'IL20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0199 (Fisher's exact test), Q value = 0.15

Table S975.  Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
IL20 MUTATED 6 0 0
IL20 WILD-TYPE 98 55 81

Figure S242.  Get High-res Image Gene #89: 'IL20 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'SLC44A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.64

Table S976.  Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SLC44A3 MUTATED 0 3 2 1
SLC44A3 WILD-TYPE 71 84 52 29
'SLC44A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 0.68

Table S977.  Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SLC44A3 MUTATED 1 2 1
SLC44A3 WILD-TYPE 43 26 62
'SLC44A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 0.8

Table S978.  Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SLC44A3 MUTATED 0 2 3 0 0 1 0
SLC44A3 WILD-TYPE 24 48 28 19 22 32 24
'SLC44A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S979.  Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SLC44A3 MUTATED 2 3 1 0
SLC44A3 WILD-TYPE 66 75 30 26
'SLC44A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.728 (Fisher's exact test), Q value = 0.99

Table S980.  Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SLC44A3 MUTATED 1 3 0 2
SLC44A3 WILD-TYPE 63 70 36 72
'SLC44A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.251 (Fisher's exact test), Q value = 0.6

Table S981.  Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SLC44A3 MUTATED 0 0 0 2 2 0 2
SLC44A3 WILD-TYPE 44 41 17 31 33 31 44
'SLC44A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.704 (Fisher's exact test), Q value = 0.98

Table S982.  Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SLC44A3 MUTATED 1 0 2 2 1
SLC44A3 WILD-TYPE 40 40 62 73 19
'SLC44A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S983.  Gene #90: 'SLC44A3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SLC44A3 MUTATED 3 1 2
SLC44A3 WILD-TYPE 101 54 79
'TAP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.46

Table S984.  Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TAP1 MUTATED 0 4 2 2
TAP1 WILD-TYPE 71 83 52 28
'TAP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S985.  Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TAP1 MUTATED 1 0 2
TAP1 WILD-TYPE 43 28 61
'TAP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S986.  Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TAP1 MUTATED 1 1 2 0 1 1 1
TAP1 WILD-TYPE 23 49 29 19 21 32 23
'TAP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.675 (Fisher's exact test), Q value = 0.96

Table S987.  Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TAP1 MUTATED 1 4 1 1
TAP1 WILD-TYPE 67 74 30 25
'TAP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0112 (Fisher's exact test), Q value = 0.11

Table S988.  Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TAP1 MUTATED 1 3 4 0
TAP1 WILD-TYPE 63 70 32 74

Figure S243.  Get High-res Image Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'TAP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.003 (Fisher's exact test), Q value = 0.045

Table S989.  Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TAP1 MUTATED 0 0 1 3 4 0 0
TAP1 WILD-TYPE 44 41 16 30 31 31 46

Figure S244.  Get High-res Image Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TAP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.44

Table S990.  Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TAP1 MUTATED 1 2 4 0 0
TAP1 WILD-TYPE 40 38 60 75 20
'TAP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0473 (Fisher's exact test), Q value = 0.26

Table S991.  Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TAP1 MUTATED 6 1 0
TAP1 WILD-TYPE 98 54 81

Figure S245.  Get High-res Image Gene #91: 'TAP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RHBDD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 0.79

Table S992.  Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RHBDD3 MUTATED 0 2 1 1
RHBDD3 WILD-TYPE 71 85 53 29
'RHBDD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.65

Table S993.  Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RHBDD3 MUTATED 0 0 3
RHBDD3 WILD-TYPE 44 28 60
'RHBDD3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 0.83

Table S994.  Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RHBDD3 MUTATED 1 1 0 1 0 0 1
RHBDD3 WILD-TYPE 23 49 31 18 22 33 23
'RHBDD3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 0.38

Table S995.  Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RHBDD3 MUTATED 0 2 0 2
RHBDD3 WILD-TYPE 68 76 31 24
'RHBDD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 0.41

Table S996.  Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RHBDD3 MUTATED 1 1 2 0
RHBDD3 WILD-TYPE 63 72 34 74
'RHBDD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0244 (Fisher's exact test), Q value = 0.18

Table S997.  Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RHBDD3 MUTATED 0 0 0 3 1 0 0
RHBDD3 WILD-TYPE 44 41 17 30 34 31 46

Figure S246.  Get High-res Image Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RHBDD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0868 (Fisher's exact test), Q value = 0.35

Table S998.  Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RHBDD3 MUTATED 0 0 3 0 1
RHBDD3 WILD-TYPE 41 40 61 75 19
'RHBDD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0828 (Fisher's exact test), Q value = 0.34

Table S999.  Gene #92: 'RHBDD3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RHBDD3 MUTATED 4 0 0
RHBDD3 WILD-TYPE 100 55 81
'BRDT MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1000.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
BRDT MUTATED 1 1 1 0
BRDT WILD-TYPE 12 17 12 7
'BRDT MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S1001.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
BRDT MUTATED 1 0 1 0 1
BRDT WILD-TYPE 11 10 6 7 14
'BRDT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00617 (Fisher's exact test), Q value = 0.071

Table S1002.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
BRDT MUTATED 0 9 5 0
BRDT WILD-TYPE 71 78 49 30

Figure S247.  Get High-res Image Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'BRDT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1003.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
BRDT MUTATED 2 1 4
BRDT WILD-TYPE 42 27 59
'BRDT MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 0.8

Table S1004.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
BRDT MUTATED 1 1 4 2 2 2 1
BRDT WILD-TYPE 23 49 27 17 20 31 23
'BRDT MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.236 (Fisher's exact test), Q value = 0.58

Table S1005.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
BRDT MUTATED 2 6 4 1
BRDT WILD-TYPE 66 72 27 25
'BRDT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.48

Table S1006.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
BRDT MUTATED 2 4 5 3
BRDT WILD-TYPE 62 69 31 71
'BRDT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00777 (Fisher's exact test), Q value = 0.083

Table S1007.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
BRDT MUTATED 0 1 1 4 6 0 2
BRDT WILD-TYPE 44 40 16 29 29 31 44

Figure S248.  Get High-res Image Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'BRDT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 0.67

Table S1008.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
BRDT MUTATED 1 1 7 3 1
BRDT WILD-TYPE 40 39 57 72 19
'BRDT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 0.51

Table S1009.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
BRDT MUTATED 9 2 2
BRDT WILD-TYPE 95 53 79
'BRDT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 0.95

Table S1010.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
BRDT MUTATED 0 1 1 2
BRDT WILD-TYPE 14 46 20 28
'BRDT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.343 (Fisher's exact test), Q value = 0.68

Table S1011.  Gene #93: 'BRDT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
BRDT MUTATED 1 1 2
BRDT WILD-TYPE 33 52 23
'RB1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S1012.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
RB1 MUTATED 1 3 2 0
RB1 WILD-TYPE 12 15 11 7
'RB1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0054 (Fisher's exact test), Q value = 0.065

Table S1013.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
RB1 MUTATED 5 0 0 1 0
RB1 WILD-TYPE 7 10 7 6 15

Figure S249.  Get High-res Image Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0891 (Fisher's exact test), Q value = 0.36

Table S1014.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RB1 MUTATED 2 12 4 2
RB1 WILD-TYPE 69 75 50 28
'RB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 0.86

Table S1015.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RB1 MUTATED 2 1 6
RB1 WILD-TYPE 42 27 57
'RB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 0.89

Table S1016.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RB1 MUTATED 1 4 4 3 3 1 2
RB1 WILD-TYPE 23 46 27 16 19 32 22
'RB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 0.83

Table S1017.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RB1 MUTATED 5 6 5 2
RB1 WILD-TYPE 63 72 26 24
'RB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 0.91

Table S1018.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RB1 MUTATED 6 8 2 4
RB1 WILD-TYPE 58 65 34 70
'RB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00013 (Fisher's exact test), Q value = 0.0055

Table S1019.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RB1 MUTATED 2 0 0 5 10 2 1
RB1 WILD-TYPE 42 41 17 28 25 29 45

Figure S250.  Get High-res Image Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.835 (Fisher's exact test), Q value = 1

Table S1020.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RB1 MUTATED 3 2 7 5 2
RB1 WILD-TYPE 38 38 57 70 18
'RB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.484 (Fisher's exact test), Q value = 0.82

Table S1021.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RB1 MUTATED 11 3 5
RB1 WILD-TYPE 93 52 76
'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1022.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RB1 MUTATED 0 2 1 1
RB1 WILD-TYPE 14 45 20 29
'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0671 (Fisher's exact test), Q value = 0.31

Table S1023.  Gene #94: 'RB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RB1 MUTATED 3 0 1
RB1 WILD-TYPE 31 53 24
'MFAP5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0369 (Fisher's exact test), Q value = 0.23

Table S1024.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MFAP5 MUTATED 0 7 2 0
MFAP5 WILD-TYPE 71 80 52 30

Figure S251.  Get High-res Image Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MFAP5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 0.77

Table S1025.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MFAP5 MUTATED 3 0 2
MFAP5 WILD-TYPE 41 28 61
'MFAP5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 0.47

Table S1026.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MFAP5 MUTATED 1 0 3 1 1 3 0
MFAP5 WILD-TYPE 23 50 28 18 21 30 24
'MFAP5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0169 (Fisher's exact test), Q value = 0.14

Table S1027.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MFAP5 MUTATED 1 3 5 0
MFAP5 WILD-TYPE 67 75 26 26

Figure S252.  Get High-res Image Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'MFAP5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00239 (Fisher's exact test), Q value = 0.039

Table S1028.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MFAP5 MUTATED 1 3 5 0
MFAP5 WILD-TYPE 63 70 31 74

Figure S253.  Get High-res Image Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MFAP5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00283 (Fisher's exact test), Q value = 0.043

Table S1029.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MFAP5 MUTATED 0 0 3 2 3 1 0
MFAP5 WILD-TYPE 44 41 14 31 32 30 46

Figure S254.  Get High-res Image Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MFAP5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00492 (Fisher's exact test), Q value = 0.062

Table S1030.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MFAP5 MUTATED 0 1 7 0 1
MFAP5 WILD-TYPE 41 39 57 75 19

Figure S255.  Get High-res Image Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'MFAP5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.183 (Fisher's exact test), Q value = 0.51

Table S1031.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MFAP5 MUTATED 4 4 1
MFAP5 WILD-TYPE 100 51 80
'MFAP5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.54

Table S1032.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MFAP5 MUTATED 0 0 1 2
MFAP5 WILD-TYPE 14 47 20 28
'MFAP5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 0.46

Table S1033.  Gene #95: 'MFAP5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MFAP5 MUTATED 2 0 1
MFAP5 WILD-TYPE 32 53 24
'NAA15 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.552 (Fisher's exact test), Q value = 0.87

Table S1034.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
NAA15 MUTATED 2 2 0 0
NAA15 WILD-TYPE 11 16 13 7
'NAA15 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.25 (Fisher's exact test), Q value = 0.6

Table S1035.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
NAA15 MUTATED 2 0 1 1 0
NAA15 WILD-TYPE 10 10 6 6 15
'NAA15 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 0.85

Table S1036.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NAA15 MUTATED 3 8 2 1
NAA15 WILD-TYPE 68 79 52 29
'NAA15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0751 (Fisher's exact test), Q value = 0.33

Table S1037.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
NAA15 MUTATED 5 1 1
NAA15 WILD-TYPE 39 27 62
'NAA15 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 0.76

Table S1038.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NAA15 MUTATED 0 4 4 1 1 3 0
NAA15 WILD-TYPE 24 46 27 18 21 30 24
'NAA15 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.484 (Fisher's exact test), Q value = 0.82

Table S1039.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NAA15 MUTATED 2 7 2 2
NAA15 WILD-TYPE 66 71 29 24
'NAA15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.46

Table S1040.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NAA15 MUTATED 3 4 5 2
NAA15 WILD-TYPE 61 69 31 72
'NAA15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00107 (Fisher's exact test), Q value = 0.024

Table S1041.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NAA15 MUTATED 0 0 3 4 5 0 2
NAA15 WILD-TYPE 44 41 14 29 30 31 44

Figure S256.  Get High-res Image Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NAA15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0693 (Fisher's exact test), Q value = 0.32

Table S1042.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NAA15 MUTATED 2 0 7 2 2
NAA15 WILD-TYPE 39 40 57 73 18
'NAA15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 0.65

Table S1043.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NAA15 MUTATED 7 4 2
NAA15 WILD-TYPE 97 51 79
'NAA15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.48

Table S1044.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
NAA15 MUTATED 0 1 1 4
NAA15 WILD-TYPE 14 46 20 26
'NAA15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.156 (Fisher's exact test), Q value = 0.47

Table S1045.  Gene #96: 'NAA15 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
NAA15 MUTATED 2 1 3
NAA15 WILD-TYPE 32 52 22
'ZRANB3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.47

Table S1046.  Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZRANB3 MUTATED 0 5 1 1
ZRANB3 WILD-TYPE 71 82 53 29
'ZRANB3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 0.75

Table S1047.  Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZRANB3 MUTATED 0 1 3 0 1 1 0
ZRANB3 WILD-TYPE 24 49 28 19 21 32 24
'ZRANB3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00853 (Fisher's exact test), Q value = 0.089

Table S1048.  Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZRANB3 MUTATED 0 2 4 0
ZRANB3 WILD-TYPE 68 76 27 26

Figure S257.  Get High-res Image Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'ZRANB3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0372 (Fisher's exact test), Q value = 0.23

Table S1049.  Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZRANB3 MUTATED 1 3 3 0
ZRANB3 WILD-TYPE 63 70 33 74

Figure S258.  Get High-res Image Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ZRANB3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00505 (Fisher's exact test), Q value = 0.063

Table S1050.  Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZRANB3 MUTATED 0 0 1 2 4 0 0
ZRANB3 WILD-TYPE 44 41 16 31 31 31 46

Figure S259.  Get High-res Image Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZRANB3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0322 (Fisher's exact test), Q value = 0.21

Table S1051.  Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZRANB3 MUTATED 0 1 5 0 0
ZRANB3 WILD-TYPE 41 39 59 75 20

Figure S260.  Get High-res Image Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ZRANB3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 0.44

Table S1052.  Gene #97: 'ZRANB3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZRANB3 MUTATED 4 2 0
ZRANB3 WILD-TYPE 100 53 81
'SLC34A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 0.54

Table S1053.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SLC34A3 MUTATED 0 4 2 0
SLC34A3 WILD-TYPE 71 83 52 30
'SLC34A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S1054.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SLC34A3 MUTATED 2 0 3
SLC34A3 WILD-TYPE 42 28 60
'SLC34A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 0.43

Table S1055.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SLC34A3 MUTATED 1 0 3 0 0 1 0
SLC34A3 WILD-TYPE 23 50 28 19 22 32 24
'SLC34A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.403 (Fisher's exact test), Q value = 0.75

Table S1056.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SLC34A3 MUTATED 1 2 2 0
SLC34A3 WILD-TYPE 67 76 29 26
'SLC34A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0393 (Fisher's exact test), Q value = 0.23

Table S1057.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SLC34A3 MUTATED 2 0 3 1
SLC34A3 WILD-TYPE 62 73 33 73

Figure S261.  Get High-res Image Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SLC34A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0406 (Fisher's exact test), Q value = 0.24

Table S1058.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SLC34A3 MUTATED 0 0 1 3 1 1 0
SLC34A3 WILD-TYPE 44 41 16 30 34 30 46

Figure S262.  Get High-res Image Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SLC34A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 0.81

Table S1059.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SLC34A3 MUTATED 1 0 3 1 1
SLC34A3 WILD-TYPE 40 40 61 74 19
'SLC34A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.577 (Fisher's exact test), Q value = 0.88

Table S1060.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SLC34A3 MUTATED 4 1 1
SLC34A3 WILD-TYPE 100 54 80
'SLC34A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 0.7

Table S1061.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SLC34A3 MUTATED 0 1 1 3
SLC34A3 WILD-TYPE 14 46 20 27
'SLC34A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0432 (Fisher's exact test), Q value = 0.25

Table S1062.  Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SLC34A3 MUTATED 3 0 2
SLC34A3 WILD-TYPE 31 53 23

Figure S263.  Get High-res Image Gene #98: 'SLC34A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MLH3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1063.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MLH3 MUTATED 1 2 1 0
MLH3 WILD-TYPE 12 16 12 7
'MLH3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0484 (Fisher's exact test), Q value = 0.26

Table S1064.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MLH3 MUTATED 2 0 2 0 0
MLH3 WILD-TYPE 10 10 5 7 15

Figure S264.  Get High-res Image Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MLH3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00086 (Fisher's exact test), Q value = 0.021

Table S1065.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MLH3 MUTATED 1 14 2 0
MLH3 WILD-TYPE 70 73 52 30

Figure S265.  Get High-res Image Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MLH3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1066.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MLH3 MUTATED 3 2 4
MLH3 WILD-TYPE 41 26 59
'MLH3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.492 (Fisher's exact test), Q value = 0.83

Table S1067.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MLH3 MUTATED 1 1 4 2 2 3 2
MLH3 WILD-TYPE 23 49 27 17 20 30 22
'MLH3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.561 (Fisher's exact test), Q value = 0.87

Table S1068.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MLH3 MUTATED 4 6 4 1
MLH3 WILD-TYPE 64 72 27 25
'MLH3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.212 (Fisher's exact test), Q value = 0.54

Table S1069.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MLH3 MUTATED 2 4 5 6
MLH3 WILD-TYPE 62 69 31 68
'MLH3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0532 (Fisher's exact test), Q value = 0.28

Table S1070.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MLH3 MUTATED 0 1 2 4 5 1 4
MLH3 WILD-TYPE 44 40 15 29 30 30 42
'MLH3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 0.55

Table S1071.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MLH3 MUTATED 0 2 7 6 1
MLH3 WILD-TYPE 41 38 57 69 19
'MLH3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S1072.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MLH3 MUTATED 8 3 5
MLH3 WILD-TYPE 96 52 76
'MLH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.943 (Fisher's exact test), Q value = 1

Table S1073.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MLH3 MUTATED 0 4 1 2
MLH3 WILD-TYPE 14 43 20 28
'MLH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1074.  Gene #99: 'MLH3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MLH3 MUTATED 3 3 1
MLH3 WILD-TYPE 31 50 24
'CCDC147 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S1075.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CCDC147 MUTATED 2 1 1 0
CCDC147 WILD-TYPE 11 17 12 7
'CCDC147 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0909 (Fisher's exact test), Q value = 0.36

Table S1076.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CCDC147 MUTATED 1 0 2 1 0
CCDC147 WILD-TYPE 11 10 5 6 15
'CCDC147 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00089 (Fisher's exact test), Q value = 0.021

Table S1077.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CCDC147 MUTATED 0 12 3 0
CCDC147 WILD-TYPE 71 75 51 30

Figure S266.  Get High-res Image Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CCDC147 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 0.75

Table S1078.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CCDC147 MUTATED 3 0 5
CCDC147 WILD-TYPE 41 28 58
'CCDC147 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.42

Table S1079.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CCDC147 MUTATED 1 0 4 2 2 3 1
CCDC147 WILD-TYPE 23 50 27 17 20 30 23
'CCDC147 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.013 (Fisher's exact test), Q value = 0.12

Table S1080.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CCDC147 MUTATED 1 5 6 1
CCDC147 WILD-TYPE 67 73 25 25

Figure S267.  Get High-res Image Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'CCDC147 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00158 (Fisher's exact test), Q value = 0.031

Table S1081.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CCDC147 MUTATED 2 3 8 2
CCDC147 WILD-TYPE 62 70 28 72

Figure S268.  Get High-res Image Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'CCDC147 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00013 (Fisher's exact test), Q value = 0.0055

Table S1082.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CCDC147 MUTATED 0 0 2 6 5 2 0
CCDC147 WILD-TYPE 44 41 15 27 30 29 46

Figure S269.  Get High-res Image Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC147 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00051 (Fisher's exact test), Q value = 0.015

Table S1083.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CCDC147 MUTATED 0 1 11 1 1
CCDC147 WILD-TYPE 41 39 53 74 19

Figure S270.  Get High-res Image Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CCDC147 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.224 (Fisher's exact test), Q value = 0.56

Table S1084.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CCDC147 MUTATED 9 3 2
CCDC147 WILD-TYPE 95 52 79
'CCDC147 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 0.7

Table S1085.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CCDC147 MUTATED 0 1 1 3
CCDC147 WILD-TYPE 14 46 20 27
'CCDC147 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0427 (Fisher's exact test), Q value = 0.25

Table S1086.  Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CCDC147 MUTATED 3 0 2
CCDC147 WILD-TYPE 31 53 23

Figure S271.  Get High-res Image Gene #100: 'CCDC147 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ZNF662 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.504 (Fisher's exact test), Q value = 0.83

Table S1087.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZNF662 MUTATED 2 1 0 0
ZNF662 WILD-TYPE 11 17 13 7
'ZNF662 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S1088.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZNF662 MUTATED 1 0 1 1 0
ZNF662 WILD-TYPE 11 10 6 6 15
'ZNF662 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.48

Table S1089.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF662 MUTATED 1 8 3 1
ZNF662 WILD-TYPE 70 79 51 29
'ZNF662 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 0.75

Table S1090.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF662 MUTATED 3 0 5
ZNF662 WILD-TYPE 41 28 58
'ZNF662 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 0.69

Table S1091.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF662 MUTATED 1 1 3 2 3 1 1
ZNF662 WILD-TYPE 23 49 28 17 19 32 23
'ZNF662 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.129 (Fisher's exact test), Q value = 0.43

Table S1092.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF662 MUTATED 1 8 2 1
ZNF662 WILD-TYPE 67 70 29 25
'ZNF662 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.012 (Fisher's exact test), Q value = 0.12

Table S1093.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF662 MUTATED 2 4 6 1
ZNF662 WILD-TYPE 62 69 30 73

Figure S272.  Get High-res Image Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ZNF662 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 4e-05 (Fisher's exact test), Q value = 0.0023

Table S1094.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF662 MUTATED 0 0 2 6 5 0 0
ZNF662 WILD-TYPE 44 41 15 27 30 31 46

Figure S273.  Get High-res Image Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF662 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0181 (Fisher's exact test), Q value = 0.15

Table S1095.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF662 MUTATED 2 0 8 1 1
ZNF662 WILD-TYPE 39 40 56 74 19

Figure S274.  Get High-res Image Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ZNF662 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 0.46

Table S1096.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF662 MUTATED 8 3 1
ZNF662 WILD-TYPE 96 52 80
'ZNF662 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 0.7

Table S1097.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF662 MUTATED 0 1 1 3
ZNF662 WILD-TYPE 14 46 20 27
'ZNF662 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0423 (Fisher's exact test), Q value = 0.25

Table S1098.  Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF662 MUTATED 3 0 2
ZNF662 WILD-TYPE 31 53 23

Figure S275.  Get High-res Image Gene #101: 'ZNF662 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PSMC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00375 (Fisher's exact test), Q value = 0.052

Table S1099.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PSMC4 MUTATED 0 9 1 0
PSMC4 WILD-TYPE 71 78 53 30

Figure S276.  Get High-res Image Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PSMC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 0.98

Table S1100.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PSMC4 MUTATED 2 0 3
PSMC4 WILD-TYPE 42 28 60
'PSMC4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 0.59

Table S1101.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PSMC4 MUTATED 0 0 2 1 2 2 1
PSMC4 WILD-TYPE 24 50 29 18 20 31 23
'PSMC4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 0.84

Table S1102.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PSMC4 MUTATED 1 4 2 1
PSMC4 WILD-TYPE 67 74 29 25
'PSMC4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.975 (Fisher's exact test), Q value = 1

Table S1103.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PSMC4 MUTATED 3 3 2 3
PSMC4 WILD-TYPE 61 70 34 71
'PSMC4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00868 (Fisher's exact test), Q value = 0.09

Table S1104.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PSMC4 MUTATED 0 0 1 1 6 1 2
PSMC4 WILD-TYPE 44 41 16 32 29 30 44

Figure S277.  Get High-res Image Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PSMC4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0991 (Fisher's exact test), Q value = 0.37

Table S1105.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PSMC4 MUTATED 0 0 6 3 1
PSMC4 WILD-TYPE 41 40 58 72 19
'PSMC4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1106.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PSMC4 MUTATED 5 2 3
PSMC4 WILD-TYPE 99 53 78
'PSMC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0715 (Fisher's exact test), Q value = 0.32

Table S1107.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PSMC4 MUTATED 0 0 1 3
PSMC4 WILD-TYPE 14 47 20 27
'PSMC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 0.87

Table S1108.  Gene #102: 'PSMC4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PSMC4 MUTATED 2 1 1
PSMC4 WILD-TYPE 32 52 24
'CCDC160 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S1109.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CCDC160 MUTATED 1 2 0 0
CCDC160 WILD-TYPE 12 16 13 7
'CCDC160 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 0.53

Table S1110.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CCDC160 MUTATED 2 0 0 1 0
CCDC160 WILD-TYPE 10 10 7 6 15
'CCDC160 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0173 (Fisher's exact test), Q value = 0.14

Table S1111.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CCDC160 MUTATED 0 8 1 2
CCDC160 WILD-TYPE 71 79 53 28

Figure S278.  Get High-res Image Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CCDC160 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1112.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CCDC160 MUTATED 1 1 2
CCDC160 WILD-TYPE 43 27 61
'CCDC160 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S1113.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CCDC160 MUTATED 1 2 3 0 2 1 1
CCDC160 WILD-TYPE 23 48 28 19 20 32 23
'CCDC160 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 0.91

Table S1114.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CCDC160 MUTATED 3 3 3 1
CCDC160 WILD-TYPE 65 75 28 25
'CCDC160 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S1115.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CCDC160 MUTATED 3 4 2 2
CCDC160 WILD-TYPE 61 69 34 72
'CCDC160 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.026 (Fisher's exact test), Q value = 0.19

Table S1116.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CCDC160 MUTATED 0 1 1 4 4 0 1
CCDC160 WILD-TYPE 44 40 16 29 31 31 45

Figure S279.  Get High-res Image Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC160 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 0.63

Table S1117.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CCDC160 MUTATED 0 2 5 2 1
CCDC160 WILD-TYPE 41 38 59 73 19
'CCDC160 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 0.91

Table S1118.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CCDC160 MUTATED 6 2 2
CCDC160 WILD-TYPE 98 53 79
'CCDC160 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 0.99

Table S1119.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CCDC160 MUTATED 0 2 1 0
CCDC160 WILD-TYPE 14 45 20 30
'CCDC160 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S1120.  Gene #103: 'CCDC160 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CCDC160 MUTATED 1 1 1
CCDC160 WILD-TYPE 33 52 24
'PPIL4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S1121.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PPIL4 MUTATED 2 1 0 0
PPIL4 WILD-TYPE 11 17 13 7
'PPIL4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S1122.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PPIL4 MUTATED 1 0 1 1 0
PPIL4 WILD-TYPE 11 10 6 6 15
'PPIL4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0963 (Fisher's exact test), Q value = 0.36

Table S1123.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PPIL4 MUTATED 1 8 1 1
PPIL4 WILD-TYPE 70 79 53 29
'PPIL4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1124.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PPIL4 MUTATED 3 1 4
PPIL4 WILD-TYPE 41 27 59
'PPIL4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S1125.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PPIL4 MUTATED 1 2 2 2 1 1 2
PPIL4 WILD-TYPE 23 48 29 17 21 32 22
'PPIL4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 0.51

Table S1126.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PPIL4 MUTATED 2 7 0 2
PPIL4 WILD-TYPE 66 71 31 24
'PPIL4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.61

Table S1127.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PPIL4 MUTATED 4 3 3 1
PPIL4 WILD-TYPE 60 70 33 73
'PPIL4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00233 (Fisher's exact test), Q value = 0.039

Table S1128.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PPIL4 MUTATED 2 0 1 6 2 0 0
PPIL4 WILD-TYPE 42 41 16 27 33 31 46

Figure S280.  Get High-res Image Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PPIL4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0437 (Fisher's exact test), Q value = 0.25

Table S1129.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PPIL4 MUTATED 2 0 7 1 1
PPIL4 WILD-TYPE 39 40 57 74 19

Figure S281.  Get High-res Image Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PPIL4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.104 (Fisher's exact test), Q value = 0.38

Table S1130.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PPIL4 MUTATED 8 2 1
PPIL4 WILD-TYPE 96 53 80
'PPIL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 0.75

Table S1131.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PPIL4 MUTATED 1 1 1 3
PPIL4 WILD-TYPE 13 46 20 27
'PPIL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00557 (Fisher's exact test), Q value = 0.066

Table S1132.  Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PPIL4 MUTATED 5 0 1
PPIL4 WILD-TYPE 29 53 24

Figure S282.  Get High-res Image Gene #104: 'PPIL4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CCDC144A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S1133.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CCDC144A MUTATED 2 2 1 0
CCDC144A WILD-TYPE 11 16 12 7
'CCDC144A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0912 (Fisher's exact test), Q value = 0.36

Table S1134.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CCDC144A MUTATED 2 0 2 1 0
CCDC144A WILD-TYPE 10 10 5 6 15
'CCDC144A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0367 (Fisher's exact test), Q value = 0.23

Table S1135.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CCDC144A MUTATED 2 11 5 0
CCDC144A WILD-TYPE 69 76 49 30

Figure S283.  Get High-res Image Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CCDC144A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S1136.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CCDC144A MUTATED 3 1 5
CCDC144A WILD-TYPE 41 27 58
'CCDC144A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 0.59

Table S1137.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CCDC144A MUTATED 2 2 5 2 3 2 0
CCDC144A WILD-TYPE 22 48 26 17 19 31 24
'CCDC144A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.332 (Fisher's exact test), Q value = 0.67

Table S1138.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CCDC144A MUTATED 5 7 4 0
CCDC144A WILD-TYPE 63 71 27 26
'CCDC144A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 0.69

Table S1139.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CCDC144A MUTATED 3 6 5 4
CCDC144A WILD-TYPE 61 67 31 70
'CCDC144A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00386 (Fisher's exact test), Q value = 0.053

Table S1140.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CCDC144A MUTATED 0 1 2 6 6 1 2
CCDC144A WILD-TYPE 44 40 15 27 29 30 44

Figure S284.  Get High-res Image Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC144A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 0.55

Table S1141.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CCDC144A MUTATED 2 1 9 4 1
CCDC144A WILD-TYPE 39 39 55 71 19
'CCDC144A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 0.53

Table S1142.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CCDC144A MUTATED 11 3 3
CCDC144A WILD-TYPE 93 52 78
'CCDC144A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S1143.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CCDC144A MUTATED 0 3 1 3
CCDC144A WILD-TYPE 14 44 20 27
'CCDC144A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.414 (Fisher's exact test), Q value = 0.76

Table S1144.  Gene #105: 'CCDC144A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CCDC144A MUTATED 2 2 3
CCDC144A WILD-TYPE 32 51 22
'TUBGCP6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0154 (Fisher's exact test), Q value = 0.13

Table S1145.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TUBGCP6 MUTATED 1 13 4 2
TUBGCP6 WILD-TYPE 70 74 50 28

Figure S285.  Get High-res Image Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TUBGCP6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.51

Table S1146.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TUBGCP6 MUTATED 2 1 9
TUBGCP6 WILD-TYPE 42 27 54
'TUBGCP6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 0.73

Table S1147.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TUBGCP6 MUTATED 3 1 4 1 1 4 2
TUBGCP6 WILD-TYPE 21 49 27 18 21 29 22
'TUBGCP6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.64

Table S1148.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TUBGCP6 MUTATED 5 4 5 2
TUBGCP6 WILD-TYPE 63 74 26 24
'TUBGCP6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 0.92

Table S1149.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TUBGCP6 MUTATED 3 7 4 6
TUBGCP6 WILD-TYPE 61 66 32 68
'TUBGCP6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00086 (Fisher's exact test), Q value = 0.021

Table S1150.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TUBGCP6 MUTATED 0 1 2 6 7 0 4
TUBGCP6 WILD-TYPE 44 40 15 27 28 31 42

Figure S286.  Get High-res Image Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TUBGCP6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0648 (Fisher's exact test), Q value = 0.31

Table S1151.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TUBGCP6 MUTATED 1 2 10 4 3
TUBGCP6 WILD-TYPE 40 38 54 71 17
'TUBGCP6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 0.86

Table S1152.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TUBGCP6 MUTATED 11 3 6
TUBGCP6 WILD-TYPE 93 52 75
'TUBGCP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.963 (Fisher's exact test), Q value = 1

Table S1153.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
TUBGCP6 MUTATED 1 5 2 2
TUBGCP6 WILD-TYPE 13 42 19 28
'TUBGCP6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.91 (Fisher's exact test), Q value = 1

Table S1154.  Gene #106: 'TUBGCP6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
TUBGCP6 MUTATED 4 4 2
TUBGCP6 WILD-TYPE 30 49 23
'TTC39C MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S1155.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
TTC39C MUTATED 1 2 0 0
TTC39C WILD-TYPE 12 16 13 7
'TTC39C MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.53

Table S1156.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
TTC39C MUTATED 2 0 0 1 0
TTC39C WILD-TYPE 10 10 7 6 15
'TTC39C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0571 (Fisher's exact test), Q value = 0.29

Table S1157.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TTC39C MUTATED 0 6 1 0
TTC39C WILD-TYPE 71 81 53 30
'TTC39C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.152 (Fisher's exact test), Q value = 0.47

Table S1158.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TTC39C MUTATED 0 1 4 0 1 1 0
TTC39C WILD-TYPE 24 49 27 19 21 32 24
'TTC39C MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.235 (Fisher's exact test), Q value = 0.58

Table S1159.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TTC39C MUTATED 2 2 3 0
TTC39C WILD-TYPE 66 76 28 26
'TTC39C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 0.43

Table S1160.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TTC39C MUTATED 0 4 2 1
TTC39C WILD-TYPE 64 69 34 73
'TTC39C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0266 (Fisher's exact test), Q value = 0.19

Table S1161.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TTC39C MUTATED 0 0 0 2 4 0 1
TTC39C WILD-TYPE 44 41 17 31 31 31 45

Figure S287.  Get High-res Image Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TTC39C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S1162.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TTC39C MUTATED 1 1 3 1 0
TTC39C WILD-TYPE 40 39 61 74 20
'TTC39C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 0.88

Table S1163.  Gene #107: 'TTC39C MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TTC39C MUTATED 4 1 1
TTC39C WILD-TYPE 100 54 80
'COL8A1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0558 (Fisher's exact test), Q value = 0.28

Table S1164.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
COL8A1 MUTATED 3 0 0 0
COL8A1 WILD-TYPE 10 18 13 7
'COL8A1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 0.45

Table S1165.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
COL8A1 MUTATED 0 0 2 0 1
COL8A1 WILD-TYPE 12 10 5 7 14
'COL8A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0906 (Fisher's exact test), Q value = 0.36

Table S1166.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
COL8A1 MUTATED 0 5 4 1
COL8A1 WILD-TYPE 71 82 50 29
'COL8A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 0.98

Table S1167.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
COL8A1 MUTATED 2 0 3
COL8A1 WILD-TYPE 42 28 60
'COL8A1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 0.73

Table S1168.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
COL8A1 MUTATED 0 1 3 1 0 2 2
COL8A1 WILD-TYPE 24 49 28 18 22 31 22
'COL8A1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 0.65

Table S1169.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
COL8A1 MUTATED 1 5 1 2
COL8A1 WILD-TYPE 67 73 30 24
'COL8A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00095 (Fisher's exact test), Q value = 0.022

Table S1170.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
COL8A1 MUTATED 2 2 6 0
COL8A1 WILD-TYPE 62 71 30 74

Figure S288.  Get High-res Image Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'COL8A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0136 (Fisher's exact test), Q value = 0.12

Table S1171.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
COL8A1 MUTATED 0 1 1 5 2 1 0
COL8A1 WILD-TYPE 44 40 16 28 33 30 46

Figure S289.  Get High-res Image Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'COL8A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00577 (Fisher's exact test), Q value = 0.068

Table S1172.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
COL8A1 MUTATED 2 0 7 0 1
COL8A1 WILD-TYPE 39 40 57 75 19

Figure S290.  Get High-res Image Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'COL8A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0173 (Fisher's exact test), Q value = 0.14

Table S1173.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
COL8A1 MUTATED 8 2 0
COL8A1 WILD-TYPE 96 53 81

Figure S291.  Get High-res Image Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'COL8A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.47

Table S1174.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
COL8A1 MUTATED 1 0 1 2
COL8A1 WILD-TYPE 13 47 20 28
'COL8A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0931 (Fisher's exact test), Q value = 0.36

Table S1175.  Gene #108: 'COL8A1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
COL8A1 MUTATED 2 0 2
COL8A1 WILD-TYPE 32 53 23
'PER3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0145 (Fisher's exact test), Q value = 0.13

Table S1176.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PER3 MUTATED 0 8 4 0
PER3 WILD-TYPE 71 79 50 30

Figure S292.  Get High-res Image Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PER3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 0.7

Table S1177.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PER3 MUTATED 2 0 5
PER3 WILD-TYPE 42 28 58
'PER3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.53

Table S1178.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PER3 MUTATED 0 1 4 2 2 1 1
PER3 WILD-TYPE 24 49 27 17 20 32 23
'PER3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 0.54

Table S1179.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PER3 MUTATED 1 7 2 1
PER3 WILD-TYPE 67 71 29 25
'PER3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.46

Table S1180.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PER3 MUTATED 3 4 4 1
PER3 WILD-TYPE 61 69 32 73
'PER3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00072 (Fisher's exact test), Q value = 0.018

Table S1181.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PER3 MUTATED 0 0 1 4 6 0 1
PER3 WILD-TYPE 44 41 16 29 29 31 45

Figure S293.  Get High-res Image Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PER3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0877 (Fisher's exact test), Q value = 0.36

Table S1182.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PER3 MUTATED 1 1 7 1 1
PER3 WILD-TYPE 40 39 57 74 19
'PER3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0458 (Fisher's exact test), Q value = 0.26

Table S1183.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PER3 MUTATED 9 1 1
PER3 WILD-TYPE 95 54 80

Figure S294.  Get High-res Image Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PER3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0715 (Fisher's exact test), Q value = 0.32

Table S1184.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PER3 MUTATED 0 0 1 3
PER3 WILD-TYPE 14 47 20 27
'PER3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0924 (Fisher's exact test), Q value = 0.36

Table S1185.  Gene #109: 'PER3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PER3 MUTATED 2 0 2
PER3 WILD-TYPE 32 53 23
'MGA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 0.67

Table S1186.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MGA MUTATED 3 2 0 1
MGA WILD-TYPE 10 16 13 6
'MGA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 0.7

Table S1187.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MGA MUTATED 2 0 1 2 1
MGA WILD-TYPE 10 10 6 5 14
'MGA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.52

Table S1188.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MGA MUTATED 4 14 6 2
MGA WILD-TYPE 67 73 48 28
'MGA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1189.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MGA MUTATED 4 3 6
MGA WILD-TYPE 40 25 57
'MGA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0366 (Fisher's exact test), Q value = 0.23

Table S1190.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MGA MUTATED 0 2 5 5 4 4 3
MGA WILD-TYPE 24 48 26 14 18 29 21

Figure S295.  Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'MGA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.164 (Fisher's exact test), Q value = 0.48

Table S1191.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MGA MUTATED 4 11 6 2
MGA WILD-TYPE 64 67 25 24
'MGA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00388 (Fisher's exact test), Q value = 0.053

Table S1192.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MGA MUTATED 6 9 9 2
MGA WILD-TYPE 58 64 27 72

Figure S296.  Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MGA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00212 (Fisher's exact test), Q value = 0.037

Table S1193.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MGA MUTATED 3 1 3 7 9 1 2
MGA WILD-TYPE 41 40 14 26 26 30 44

Figure S297.  Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MGA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0424 (Fisher's exact test), Q value = 0.25

Table S1194.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MGA MUTATED 5 2 12 3 2
MGA WILD-TYPE 36 38 52 72 18

Figure S298.  Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'MGA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.161 (Fisher's exact test), Q value = 0.47

Table S1195.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MGA MUTATED 13 7 4
MGA WILD-TYPE 91 48 77
'MGA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0346 (Fisher's exact test), Q value = 0.22

Table S1196.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MGA MUTATED 3 1 2 5
MGA WILD-TYPE 11 46 19 25

Figure S299.  Get High-res Image Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'MGA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0935 (Fisher's exact test), Q value = 0.36

Table S1197.  Gene #110: 'MGA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MGA MUTATED 5 2 4
MGA WILD-TYPE 29 51 21
'GPRASP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.442 (Fisher's exact test), Q value = 0.78

Table S1198.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
GPRASP1 MUTATED 3 1 1 0
GPRASP1 WILD-TYPE 10 17 12 7
'GPRASP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0443 (Fisher's exact test), Q value = 0.25

Table S1199.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
GPRASP1 MUTATED 1 0 2 2 0
GPRASP1 WILD-TYPE 11 10 5 5 15

Figure S300.  Get High-res Image Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'GPRASP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0159 (Fisher's exact test), Q value = 0.14

Table S1200.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
GPRASP1 MUTATED 1 13 5 2
GPRASP1 WILD-TYPE 70 74 49 28

Figure S301.  Get High-res Image Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'GPRASP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S1201.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
GPRASP1 MUTATED 3 2 6
GPRASP1 WILD-TYPE 41 26 57
'GPRASP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S1202.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
GPRASP1 MUTATED 1 4 4 1 3 4 1
GPRASP1 WILD-TYPE 23 46 27 18 19 29 23
'GPRASP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 0.77

Table S1203.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
GPRASP1 MUTATED 4 9 4 1
GPRASP1 WILD-TYPE 64 69 27 25
'GPRASP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 0.58

Table S1204.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
GPRASP1 MUTATED 2 6 5 7
GPRASP1 WILD-TYPE 62 67 31 67
'GPRASP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 0.4

Table S1205.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
GPRASP1 MUTATED 1 1 1 6 5 2 4
GPRASP1 WILD-TYPE 43 40 16 27 30 29 42
'GPRASP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0836 (Fisher's exact test), Q value = 0.34

Table S1206.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
GPRASP1 MUTATED 2 1 11 5 1
GPRASP1 WILD-TYPE 39 39 53 70 19
'GPRASP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S1207.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
GPRASP1 MUTATED 10 3 7
GPRASP1 WILD-TYPE 94 52 74
'GPRASP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S1208.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
GPRASP1 MUTATED 1 4 1 1
GPRASP1 WILD-TYPE 13 43 20 29
'GPRASP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1209.  Gene #111: 'GPRASP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
GPRASP1 MUTATED 3 3 1
GPRASP1 WILD-TYPE 31 50 24
'PPM1D MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 0.83

Table S1210.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PPM1D MUTATED 2 1 0 0
PPM1D WILD-TYPE 11 17 13 7
'PPM1D MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.63

Table S1211.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PPM1D MUTATED 1 0 1 1 0
PPM1D WILD-TYPE 11 10 6 6 15
'PPM1D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0255 (Fisher's exact test), Q value = 0.18

Table S1212.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PPM1D MUTATED 0 7 4 0
PPM1D WILD-TYPE 71 80 50 30

Figure S302.  Get High-res Image Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PPM1D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 0.57

Table S1213.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PPM1D MUTATED 0 1 4
PPM1D WILD-TYPE 44 27 59
'PPM1D MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 0.75

Table S1214.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PPM1D MUTATED 1 2 4 2 1 1 0
PPM1D WILD-TYPE 23 48 27 17 21 32 24
'PPM1D MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S1215.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PPM1D MUTATED 3 4 3 1
PPM1D WILD-TYPE 65 74 28 25
'PPM1D MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0522 (Fisher's exact test), Q value = 0.27

Table S1216.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PPM1D MUTATED 1 5 4 1
PPM1D WILD-TYPE 63 68 32 73
'PPM1D MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0422 (Fisher's exact test), Q value = 0.25

Table S1217.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PPM1D MUTATED 0 1 0 3 5 1 1
PPM1D WILD-TYPE 44 40 17 30 30 30 45

Figure S303.  Get High-res Image Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PPM1D MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.811 (Fisher's exact test), Q value = 1

Table S1218.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PPM1D MUTATED 2 1 4 2 1
PPM1D WILD-TYPE 39 39 60 73 19
'PPM1D MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 0.68

Table S1219.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PPM1D MUTATED 7 1 2
PPM1D WILD-TYPE 97 54 79
'PPM1D MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 0.95

Table S1220.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PPM1D MUTATED 0 1 1 2
PPM1D WILD-TYPE 14 46 20 28
'PPM1D MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 0.87

Table S1221.  Gene #112: 'PPM1D MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PPM1D MUTATED 2 1 1
PPM1D WILD-TYPE 32 52 24
'ZNF674 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.089 (Fisher's exact test), Q value = 0.36

Table S1222.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF674 MUTATED 1 9 2 2
ZNF674 WILD-TYPE 70 78 52 28
'ZNF674 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 0.82

Table S1223.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF674 MUTATED 2 0 4
ZNF674 WILD-TYPE 42 28 59
'ZNF674 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 0.83

Table S1224.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF674 MUTATED 1 3 4 0 2 2 0
ZNF674 WILD-TYPE 23 47 27 19 20 31 24
'ZNF674 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.179 (Fisher's exact test), Q value = 0.51

Table S1225.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF674 MUTATED 2 7 3 0
ZNF674 WILD-TYPE 66 71 28 26
'ZNF674 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 0.69

Table S1226.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF674 MUTATED 3 7 2 2
ZNF674 WILD-TYPE 61 66 34 72
'ZNF674 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00206 (Fisher's exact test), Q value = 0.036

Table S1227.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF674 MUTATED 0 1 2 4 6 0 1
ZNF674 WILD-TYPE 44 40 15 29 29 31 45

Figure S304.  Get High-res Image Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF674 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.63

Table S1228.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF674 MUTATED 1 2 7 2 1
ZNF674 WILD-TYPE 40 38 57 73 19
'ZNF674 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.286 (Fisher's exact test), Q value = 0.63

Table S1229.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF674 MUTATED 8 3 2
ZNF674 WILD-TYPE 96 52 79
'ZNF674 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1230.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF674 MUTATED 0 2 1 1
ZNF674 WILD-TYPE 14 45 20 29
'ZNF674 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.559 (Fisher's exact test), Q value = 0.87

Table S1231.  Gene #113: 'ZNF674 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF674 MUTATED 2 1 1
ZNF674 WILD-TYPE 32 52 24
'LIMK2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.61

Table S1232.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
LIMK2 MUTATED 2 0 1 0
LIMK2 WILD-TYPE 11 18 12 7
'LIMK2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.452 (Fisher's exact test), Q value = 0.79

Table S1233.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
LIMK2 MUTATED 0 0 1 1 1
LIMK2 WILD-TYPE 12 10 6 6 14
'LIMK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 0.62

Table S1234.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
LIMK2 MUTATED 1 7 3 1
LIMK2 WILD-TYPE 70 80 51 29
'LIMK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S1235.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
LIMK2 MUTATED 3 1 2
LIMK2 WILD-TYPE 41 27 61
'LIMK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 0.96

Table S1236.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
LIMK2 MUTATED 1 2 2 1 1 4 0
LIMK2 WILD-TYPE 23 48 29 18 21 29 24
'LIMK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.214 (Fisher's exact test), Q value = 0.54

Table S1237.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
LIMK2 MUTATED 3 4 4 0
LIMK2 WILD-TYPE 65 74 27 26
'LIMK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 0.38

Table S1238.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
LIMK2 MUTATED 2 1 4 5
LIMK2 WILD-TYPE 62 72 32 69
'LIMK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.306 (Fisher's exact test), Q value = 0.65

Table S1239.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
LIMK2 MUTATED 1 0 1 2 2 1 5
LIMK2 WILD-TYPE 43 41 16 31 33 30 41
'LIMK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.52

Table S1240.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
LIMK2 MUTATED 1 0 6 5 0
LIMK2 WILD-TYPE 40 40 58 70 20
'LIMK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 0.67

Table S1241.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
LIMK2 MUTATED 3 3 6
LIMK2 WILD-TYPE 101 52 75
'LIMK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 0.99

Table S1242.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
LIMK2 MUTATED 1 3 0 1
LIMK2 WILD-TYPE 13 44 21 29
'LIMK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.604 (Fisher's exact test), Q value = 0.91

Table S1243.  Gene #114: 'LIMK2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
LIMK2 MUTATED 2 3 0
LIMK2 WILD-TYPE 32 50 25
'ZNF606 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.52

Table S1244.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZNF606 MUTATED 3 1 0 0
ZNF606 WILD-TYPE 10 17 13 7
'ZNF606 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0921 (Fisher's exact test), Q value = 0.36

Table S1245.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZNF606 MUTATED 1 0 1 2 0
ZNF606 WILD-TYPE 11 10 6 5 15
'ZNF606 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00541 (Fisher's exact test), Q value = 0.065

Table S1246.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF606 MUTATED 0 11 4 1
ZNF606 WILD-TYPE 71 76 50 29

Figure S305.  Get High-res Image Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF606 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 0.64

Table S1247.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF606 MUTATED 1 1 6
ZNF606 WILD-TYPE 43 27 57
'ZNF606 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S1248.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF606 MUTATED 1 2 3 2 2 2 2
ZNF606 WILD-TYPE 23 48 28 17 20 31 22
'ZNF606 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 0.99

Table S1249.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF606 MUTATED 3 7 2 2
ZNF606 WILD-TYPE 65 71 29 24
'ZNF606 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 0.58

Table S1250.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF606 MUTATED 2 5 5 4
ZNF606 WILD-TYPE 62 68 31 70
'ZNF606 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00255 (Fisher's exact test), Q value = 0.04

Table S1251.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF606 MUTATED 1 0 2 6 5 0 2
ZNF606 WILD-TYPE 43 41 15 27 30 31 44

Figure S306.  Get High-res Image Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF606 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00444 (Fisher's exact test), Q value = 0.059

Table S1252.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF606 MUTATED 1 1 11 2 0
ZNF606 WILD-TYPE 40 39 53 73 20

Figure S307.  Get High-res Image Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ZNF606 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 0.95

Table S1253.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF606 MUTATED 8 2 5
ZNF606 WILD-TYPE 96 53 76
'ZNF606 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 0.79

Table S1254.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF606 MUTATED 0 2 0 3
ZNF606 WILD-TYPE 14 45 21 27
'ZNF606 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.65

Table S1255.  Gene #115: 'ZNF606 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF606 MUTATED 3 1 1
ZNF606 WILD-TYPE 31 52 24
'SFRP4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.504 (Fisher's exact test), Q value = 0.83

Table S1256.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
SFRP4 MUTATED 2 1 0 0
SFRP4 WILD-TYPE 11 17 13 7
'SFRP4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.283 (Fisher's exact test), Q value = 0.63

Table S1257.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
SFRP4 MUTATED 1 0 1 1 0
SFRP4 WILD-TYPE 11 10 6 6 15
'SFRP4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 0.41

Table S1258.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SFRP4 MUTATED 0 3 3 2
SFRP4 WILD-TYPE 71 84 51 28
'SFRP4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 0.76

Table S1259.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SFRP4 MUTATED 0 1 3
SFRP4 WILD-TYPE 44 27 60
'SFRP4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S1260.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SFRP4 MUTATED 0 2 1 1 1 0 1
SFRP4 WILD-TYPE 24 48 30 18 21 33 23
'SFRP4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.094 (Fisher's exact test), Q value = 0.36

Table S1261.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SFRP4 MUTATED 0 5 0 1
SFRP4 WILD-TYPE 68 73 31 25
'SFRP4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 0.82

Table S1262.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SFRP4 MUTATED 3 2 2 1
SFRP4 WILD-TYPE 61 71 34 73
'SFRP4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0605 (Fisher's exact test), Q value = 0.3

Table S1263.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SFRP4 MUTATED 1 0 0 2 4 1 0
SFRP4 WILD-TYPE 43 41 17 31 31 30 46
'SFRP4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 0.85

Table S1264.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SFRP4 MUTATED 1 1 4 1 0
SFRP4 WILD-TYPE 40 39 60 74 20
'SFRP4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 0.77

Table S1265.  Gene #116: 'SFRP4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SFRP4 MUTATED 5 1 1
SFRP4 WILD-TYPE 99 54 80
'TXNRD1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S1266.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
TXNRD1 MUTATED 1 2 0 0
TXNRD1 WILD-TYPE 12 16 13 7
'TXNRD1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.53

Table S1267.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
TXNRD1 MUTATED 2 0 0 1 0
TXNRD1 WILD-TYPE 10 10 7 6 15
'TXNRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.73 (Fisher's exact test), Q value = 0.99

Table S1268.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TXNRD1 MUTATED 1 4 2 1
TXNRD1 WILD-TYPE 70 83 52 29
'TXNRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 0.96

Table S1269.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TXNRD1 MUTATED 1 0 3
TXNRD1 WILD-TYPE 43 28 60
'TXNRD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 0.85

Table S1270.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TXNRD1 MUTATED 1 2 2 1 2 0 0
TXNRD1 WILD-TYPE 23 48 29 18 20 33 24
'TXNRD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 0.65

Table S1271.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TXNRD1 MUTATED 2 3 3 0
TXNRD1 WILD-TYPE 66 75 28 26
'TXNRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.266 (Fisher's exact test), Q value = 0.62

Table S1272.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TXNRD1 MUTATED 1 5 1 1
TXNRD1 WILD-TYPE 63 68 35 73
'TXNRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0364 (Fisher's exact test), Q value = 0.23

Table S1273.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TXNRD1 MUTATED 1 0 1 3 3 0 0
TXNRD1 WILD-TYPE 43 41 16 30 32 31 46

Figure S308.  Get High-res Image Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TXNRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 0.76

Table S1274.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TXNRD1 MUTATED 3 1 3 1 0
TXNRD1 WILD-TYPE 38 39 61 74 20
'TXNRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.238 (Fisher's exact test), Q value = 0.59

Table S1275.  Gene #117: 'TXNRD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TXNRD1 MUTATED 6 1 1
TXNRD1 WILD-TYPE 98 54 80
'LETMD1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 0.83

Table S1276.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
LETMD1 MUTATED 2 1 0 0
LETMD1 WILD-TYPE 11 17 13 7
'LETMD1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.285 (Fisher's exact test), Q value = 0.63

Table S1277.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
LETMD1 MUTATED 1 0 1 1 0
LETMD1 WILD-TYPE 11 10 6 6 15
'LETMD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S1278.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
LETMD1 MUTATED 1 3 1 1
LETMD1 WILD-TYPE 70 84 53 29
'LETMD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 0.83

Table S1279.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
LETMD1 MUTATED 0 2 2 1 0 0 0
LETMD1 WILD-TYPE 24 48 29 18 22 33 24
'LETMD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 0.99

Table S1280.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
LETMD1 MUTATED 1 3 1 0
LETMD1 WILD-TYPE 67 75 30 26
'LETMD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 0.46

Table S1281.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
LETMD1 MUTATED 1 4 1 0
LETMD1 WILD-TYPE 63 69 35 74
'LETMD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0037 (Fisher's exact test), Q value = 0.052

Table S1282.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
LETMD1 MUTATED 0 0 0 4 2 0 0
LETMD1 WILD-TYPE 44 41 17 29 33 31 46

Figure S309.  Get High-res Image Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'LETMD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.073 (Fisher's exact test), Q value = 0.33

Table S1283.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
LETMD1 MUTATED 1 0 4 0 1
LETMD1 WILD-TYPE 40 40 60 75 19
'LETMD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 0.39

Table S1284.  Gene #118: 'LETMD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
LETMD1 MUTATED 5 1 0
LETMD1 WILD-TYPE 99 54 81
'ZNF721 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1285.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZNF721 MUTATED 1 1 1 0
ZNF721 WILD-TYPE 12 17 12 7
'ZNF721 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0797 (Fisher's exact test), Q value = 0.33

Table S1286.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZNF721 MUTATED 1 0 2 0 0
ZNF721 WILD-TYPE 11 10 5 7 15
'ZNF721 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00113 (Fisher's exact test), Q value = 0.024

Table S1287.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF721 MUTATED 0 11 2 0
ZNF721 WILD-TYPE 71 76 52 30

Figure S310.  Get High-res Image Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF721 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1288.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF721 MUTATED 2 1 4
ZNF721 WILD-TYPE 42 27 59
'ZNF721 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0787 (Fisher's exact test), Q value = 0.33

Table S1289.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF721 MUTATED 0 0 4 1 2 2 2
ZNF721 WILD-TYPE 24 50 27 18 20 31 22
'ZNF721 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.202 (Fisher's exact test), Q value = 0.53

Table S1290.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF721 MUTATED 1 5 3 2
ZNF721 WILD-TYPE 67 73 28 24
'ZNF721 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 0.75

Table S1291.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF721 MUTATED 2 4 4 3
ZNF721 WILD-TYPE 62 69 32 71
'ZNF721 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00544 (Fisher's exact test), Q value = 0.065

Table S1292.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF721 MUTATED 0 0 1 3 6 2 1
ZNF721 WILD-TYPE 44 41 16 30 29 29 45

Figure S311.  Get High-res Image Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF721 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.53

Table S1293.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF721 MUTATED 1 1 7 2 1
ZNF721 WILD-TYPE 40 39 57 73 19
'ZNF721 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.277 (Fisher's exact test), Q value = 0.63

Table S1294.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF721 MUTATED 8 2 2
ZNF721 WILD-TYPE 96 53 79
'ZNF721 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1295.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF721 MUTATED 0 2 1 1
ZNF721 WILD-TYPE 14 45 20 29
'ZNF721 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1296.  Gene #119: 'ZNF721 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF721 MUTATED 1 2 1
ZNF721 WILD-TYPE 33 51 24
'RASSF9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0759 (Fisher's exact test), Q value = 0.33

Table S1297.  Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RASSF9 MUTATED 0 6 2 0
RASSF9 WILD-TYPE 71 81 52 30
'RASSF9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1298.  Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RASSF9 MUTATED 1 0 2
RASSF9 WILD-TYPE 43 28 61
'RASSF9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.347 (Fisher's exact test), Q value = 0.69

Table S1299.  Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RASSF9 MUTATED 1 1 2 1 2 0 0
RASSF9 WILD-TYPE 23 49 29 18 20 33 24
'RASSF9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.706 (Fisher's exact test), Q value = 0.98

Table S1300.  Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RASSF9 MUTATED 2 3 2 0
RASSF9 WILD-TYPE 66 75 29 26
'RASSF9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S1301.  Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RASSF9 MUTATED 2 3 2 2
RASSF9 WILD-TYPE 62 70 34 72
'RASSF9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0486 (Fisher's exact test), Q value = 0.26

Table S1302.  Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RASSF9 MUTATED 0 1 0 3 4 0 1
RASSF9 WILD-TYPE 44 40 17 30 31 31 45

Figure S312.  Get High-res Image Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RASSF9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 0.98

Table S1303.  Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RASSF9 MUTATED 0 1 3 3 1
RASSF9 WILD-TYPE 41 39 61 72 19
'RASSF9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.166 (Fisher's exact test), Q value = 0.48

Table S1304.  Gene #120: 'RASSF9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RASSF9 MUTATED 6 0 2
RASSF9 WILD-TYPE 98 55 79
'AGXT2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 0.72

Table S1305.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
AGXT2 MUTATED 2 1 0 1
AGXT2 WILD-TYPE 11 17 13 6
'AGXT2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S1306.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
AGXT2 MUTATED 1 0 1 1 1
AGXT2 WILD-TYPE 11 10 6 6 14
'AGXT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0326 (Fisher's exact test), Q value = 0.21

Table S1307.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
AGXT2 MUTATED 0 8 2 1
AGXT2 WILD-TYPE 71 79 52 29

Figure S313.  Get High-res Image Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'AGXT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S1308.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
AGXT2 MUTATED 1 1 3
AGXT2 WILD-TYPE 43 27 60
'AGXT2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 0.83

Table S1309.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
AGXT2 MUTATED 0 1 2 2 2 2 1
AGXT2 WILD-TYPE 24 49 29 17 20 31 23
'AGXT2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.653 (Fisher's exact test), Q value = 0.95

Table S1310.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
AGXT2 MUTATED 2 6 1 1
AGXT2 WILD-TYPE 66 72 30 25
'AGXT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S1311.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
AGXT2 MUTATED 2 5 3 1
AGXT2 WILD-TYPE 62 68 33 73
'AGXT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00737 (Fisher's exact test), Q value = 0.08

Table S1312.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
AGXT2 MUTATED 0 1 0 4 5 0 1
AGXT2 WILD-TYPE 44 40 17 29 30 31 45

Figure S314.  Get High-res Image Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'AGXT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 0.63

Table S1313.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
AGXT2 MUTATED 0 1 5 2 1
AGXT2 WILD-TYPE 41 39 59 73 19
'AGXT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.104 (Fisher's exact test), Q value = 0.38

Table S1314.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
AGXT2 MUTATED 7 0 2
AGXT2 WILD-TYPE 97 55 79
'AGXT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S1315.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
AGXT2 MUTATED 0 1 1 1
AGXT2 WILD-TYPE 14 46 20 29
'AGXT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 0.54

Table S1316.  Gene #121: 'AGXT2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
AGXT2 MUTATED 0 1 2
AGXT2 WILD-TYPE 34 52 23
'MECOM MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 0.87

Table S1317.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MECOM MUTATED 2 2 0 0
MECOM WILD-TYPE 11 16 13 7
'MECOM MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0482 (Fisher's exact test), Q value = 0.26

Table S1318.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MECOM MUTATED 2 0 0 2 0
MECOM WILD-TYPE 10 10 7 5 15

Figure S315.  Get High-res Image Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MECOM MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0803 (Fisher's exact test), Q value = 0.33

Table S1319.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MECOM MUTATED 1 8 1 2
MECOM WILD-TYPE 70 79 53 28
'MECOM MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 0.85

Table S1320.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MECOM MUTATED 1 1 5
MECOM WILD-TYPE 43 27 58
'MECOM MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S1321.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MECOM MUTATED 0 3 2 0 1 3 2
MECOM WILD-TYPE 24 47 29 19 21 30 22
'MECOM MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 0.75

Table S1322.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MECOM MUTATED 3 6 0 2
MECOM WILD-TYPE 65 72 31 24
'MECOM MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0938 (Fisher's exact test), Q value = 0.36

Table S1323.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MECOM MUTATED 0 5 3 4
MECOM WILD-TYPE 64 68 33 70
'MECOM MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 0.61

Table S1324.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MECOM MUTATED 0 1 1 4 2 2 2
MECOM WILD-TYPE 44 40 16 29 33 29 44
'MECOM MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 0.78

Table S1325.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MECOM MUTATED 0 2 4 5 0
MECOM WILD-TYPE 41 38 60 70 20
'MECOM MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.576 (Fisher's exact test), Q value = 0.88

Table S1326.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MECOM MUTATED 5 1 5
MECOM WILD-TYPE 99 54 76
'MECOM MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.54 (Fisher's exact test), Q value = 0.86

Table S1327.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MECOM MUTATED 1 4 0 1
MECOM WILD-TYPE 13 43 21 29
'MECOM MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1328.  Gene #122: 'MECOM MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MECOM MUTATED 2 3 1
MECOM WILD-TYPE 32 50 24
'ATP6V1C2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0458 (Fisher's exact test), Q value = 0.26

Table S1329.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ATP6V1C2 MUTATED 0 7 4 1
ATP6V1C2 WILD-TYPE 71 80 50 29

Figure S316.  Get High-res Image Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ATP6V1C2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 0.64

Table S1330.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ATP6V1C2 MUTATED 1 0 5
ATP6V1C2 WILD-TYPE 43 28 58
'ATP6V1C2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.65

Table S1331.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ATP6V1C2 MUTATED 2 4 3 0 1 0 0
ATP6V1C2 WILD-TYPE 22 46 28 19 21 33 24
'ATP6V1C2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.409 (Fisher's exact test), Q value = 0.75

Table S1332.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ATP6V1C2 MUTATED 4 3 3 0
ATP6V1C2 WILD-TYPE 64 75 28 26
'ATP6V1C2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.47

Table S1333.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ATP6V1C2 MUTATED 2 7 0 3
ATP6V1C2 WILD-TYPE 62 66 36 71
'ATP6V1C2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0434 (Fisher's exact test), Q value = 0.25

Table S1334.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ATP6V1C2 MUTATED 0 3 0 3 4 2 0
ATP6V1C2 WILD-TYPE 44 38 17 30 31 29 46

Figure S317.  Get High-res Image Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ATP6V1C2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 0.81

Table S1335.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ATP6V1C2 MUTATED 0 2 5 4 1
ATP6V1C2 WILD-TYPE 41 38 59 71 19
'ATP6V1C2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 0.61

Table S1336.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ATP6V1C2 MUTATED 8 1 3
ATP6V1C2 WILD-TYPE 96 54 78
'ATP6V1C2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S1337.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ATP6V1C2 MUTATED 0 2 1 2
ATP6V1C2 WILD-TYPE 14 45 20 28
'ATP6V1C2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S1338.  Gene #123: 'ATP6V1C2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ATP6V1C2 MUTATED 1 2 2
ATP6V1C2 WILD-TYPE 33 51 23
'DYM MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0174 (Fisher's exact test), Q value = 0.14

Table S1339.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
DYM MUTATED 0 8 2 0
DYM WILD-TYPE 71 79 52 30

Figure S318.  Get High-res Image Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'DYM MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 0.82

Table S1340.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
DYM MUTATED 2 0 4
DYM WILD-TYPE 42 28 59
'DYM MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.308 (Fisher's exact test), Q value = 0.65

Table S1341.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
DYM MUTATED 1 0 1 1 2 2 2
DYM WILD-TYPE 23 50 30 18 20 31 22
'DYM MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 0.47

Table S1342.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
DYM MUTATED 1 3 3 2
DYM WILD-TYPE 67 75 28 24
'DYM MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00138 (Fisher's exact test), Q value = 0.028

Table S1343.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
DYM MUTATED 0 2 6 2
DYM WILD-TYPE 64 71 30 72

Figure S319.  Get High-res Image Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'DYM MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00336 (Fisher's exact test), Q value = 0.048

Table S1344.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
DYM MUTATED 0 0 2 4 3 1 0
DYM WILD-TYPE 44 41 15 29 32 30 46

Figure S320.  Get High-res Image Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'DYM MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0251 (Fisher's exact test), Q value = 0.18

Table S1345.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
DYM MUTATED 0 1 7 1 0
DYM WILD-TYPE 41 39 57 74 20

Figure S321.  Get High-res Image Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'DYM MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 0.66

Table S1346.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
DYM MUTATED 5 3 1
DYM WILD-TYPE 99 52 80
'DYM MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.61

Table S1347.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
DYM MUTATED 0 1 0 3
DYM WILD-TYPE 14 46 21 27
'DYM MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0658 (Fisher's exact test), Q value = 0.31

Table S1348.  Gene #124: 'DYM MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
DYM MUTATED 3 0 1
DYM WILD-TYPE 31 53 24
'TAB3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.52

Table S1349.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
TAB3 MUTATED 3 1 0 0
TAB3 WILD-TYPE 10 17 13 7
'TAB3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0913 (Fisher's exact test), Q value = 0.36

Table S1350.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
TAB3 MUTATED 1 0 1 2 0
TAB3 WILD-TYPE 11 10 6 5 15
'TAB3 MUTATION STATUS' versus 'CN_CNMF'

P value = 9e-05 (Fisher's exact test), Q value = 0.0042

Table S1351.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TAB3 MUTATED 0 15 2 1
TAB3 WILD-TYPE 71 72 52 29

Figure S322.  Get High-res Image Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TAB3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 0.83

Table S1352.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TAB3 MUTATED 3 1 7
TAB3 WILD-TYPE 41 27 56
'TAB3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.957 (Fisher's exact test), Q value = 1

Table S1353.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TAB3 MUTATED 1 4 3 1 1 1 1
TAB3 WILD-TYPE 23 46 28 18 21 32 23
'TAB3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.736 (Fisher's exact test), Q value = 0.99

Table S1354.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TAB3 MUTATED 3 5 3 1
TAB3 WILD-TYPE 65 73 28 25
'TAB3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.52

Table S1355.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TAB3 MUTATED 2 9 3 4
TAB3 WILD-TYPE 62 64 33 70
'TAB3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 3e-05 (Fisher's exact test), Q value = 0.0019

Table S1356.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TAB3 MUTATED 0 1 1 10 4 0 2
TAB3 WILD-TYPE 44 40 16 23 31 31 44

Figure S323.  Get High-res Image Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TAB3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00185 (Fisher's exact test), Q value = 0.033

Table S1357.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TAB3 MUTATED 0 1 10 3 4
TAB3 WILD-TYPE 41 39 54 72 16

Figure S324.  Get High-res Image Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'TAB3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.306 (Fisher's exact test), Q value = 0.65

Table S1358.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TAB3 MUTATED 11 2 5
TAB3 WILD-TYPE 93 53 76
'TAB3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.301 (Fisher's exact test), Q value = 0.65

Table S1359.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
TAB3 MUTATED 0 2 3 1
TAB3 WILD-TYPE 14 45 18 29
'TAB3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1360.  Gene #125: 'TAB3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
TAB3 MUTATED 2 3 1
TAB3 WILD-TYPE 32 50 24
'ZNF649 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 0.87

Table S1361.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZNF649 MUTATED 2 2 0 0
ZNF649 WILD-TYPE 11 16 13 7
'ZNF649 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 0.6

Table S1362.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZNF649 MUTATED 2 0 1 1 0
ZNF649 WILD-TYPE 10 10 6 6 15
'ZNF649 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00071 (Fisher's exact test), Q value = 0.018

Table S1363.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF649 MUTATED 0 12 1 1
ZNF649 WILD-TYPE 71 75 53 29

Figure S325.  Get High-res Image Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF649 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S1364.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF649 MUTATED 2 2 3
ZNF649 WILD-TYPE 42 26 60
'ZNF649 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.98 (Fisher's exact test), Q value = 1

Table S1365.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF649 MUTATED 1 3 3 1 2 2 2
ZNF649 WILD-TYPE 23 47 28 18 20 31 22
'ZNF649 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.955 (Fisher's exact test), Q value = 1

Table S1366.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF649 MUTATED 4 6 2 2
ZNF649 WILD-TYPE 64 72 29 24
'ZNF649 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 0.79

Table S1367.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF649 MUTATED 2 4 4 4
ZNF649 WILD-TYPE 62 69 32 70
'ZNF649 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.014 (Fisher's exact test), Q value = 0.13

Table S1368.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF649 MUTATED 1 0 1 6 3 0 3
ZNF649 WILD-TYPE 43 41 16 27 32 31 43

Figure S326.  Get High-res Image Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF649 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.152 (Fisher's exact test), Q value = 0.47

Table S1369.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF649 MUTATED 0 1 7 4 1
ZNF649 WILD-TYPE 41 39 57 71 19
'ZNF649 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S1370.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF649 MUTATED 7 2 4
ZNF649 WILD-TYPE 97 53 77
'ZNF649 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S1371.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF649 MUTATED 0 2 1 2
ZNF649 WILD-TYPE 14 45 20 28
'ZNF649 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.65

Table S1372.  Gene #126: 'ZNF649 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF649 MUTATED 3 1 1
ZNF649 WILD-TYPE 31 52 24
'FN1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 0.54

Table S1373.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
FN1 MUTATED 3 3 0 0
FN1 WILD-TYPE 10 15 13 7
'FN1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0591 (Fisher's exact test), Q value = 0.29

Table S1374.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
FN1 MUTATED 3 0 1 2 0
FN1 WILD-TYPE 9 10 6 5 15
'FN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00582 (Fisher's exact test), Q value = 0.068

Table S1375.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FN1 MUTATED 1 15 5 3
FN1 WILD-TYPE 70 72 49 27

Figure S327.  Get High-res Image Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'FN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 0.92

Table S1376.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
FN1 MUTATED 4 1 7
FN1 WILD-TYPE 40 27 56
'FN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S1377.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FN1 MUTATED 2 4 4 3 1 3 2
FN1 WILD-TYPE 22 46 27 16 21 30 22
'FN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 0.84

Table S1378.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FN1 MUTATED 4 10 3 2
FN1 WILD-TYPE 64 68 28 24
'FN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0641 (Fisher's exact test), Q value = 0.31

Table S1379.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FN1 MUTATED 6 6 8 4
FN1 WILD-TYPE 58 67 28 70
'FN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00084

Table S1380.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FN1 MUTATED 1 0 2 10 8 1 2
FN1 WILD-TYPE 43 41 15 23 27 30 44

Figure S328.  Get High-res Image Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.01 (Fisher's exact test), Q value = 0.1

Table S1381.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FN1 MUTATED 0 5 11 4 3
FN1 WILD-TYPE 41 35 53 71 17

Figure S329.  Get High-res Image Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'FN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.252 (Fisher's exact test), Q value = 0.6

Table S1382.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FN1 MUTATED 14 4 5
FN1 WILD-TYPE 90 51 76
'FN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 0.92

Table S1383.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
FN1 MUTATED 1 3 3 4
FN1 WILD-TYPE 13 44 18 26
'FN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 0.65

Table S1384.  Gene #127: 'FN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
FN1 MUTATED 4 3 4
FN1 WILD-TYPE 30 50 21
'CCDC150 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00356 (Fisher's exact test), Q value = 0.05

Table S1385.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CCDC150 MUTATED 0 9 1 0
CCDC150 WILD-TYPE 71 78 53 30

Figure S330.  Get High-res Image Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CCDC150 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 0.75

Table S1386.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CCDC150 MUTATED 3 0 5
CCDC150 WILD-TYPE 41 28 58
'CCDC150 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 0.38

Table S1387.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CCDC150 MUTATED 3 0 3 0 2 2 1
CCDC150 WILD-TYPE 21 50 28 19 20 31 23
'CCDC150 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.054 (Fisher's exact test), Q value = 0.28

Table S1388.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CCDC150 MUTATED 3 2 5 1
CCDC150 WILD-TYPE 65 76 26 25
'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 0.47

Table S1389.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CCDC150 MUTATED 1 2 4 4
CCDC150 WILD-TYPE 63 71 32 70
'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0635 (Fisher's exact test), Q value = 0.31

Table S1390.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CCDC150 MUTATED 0 0 1 4 3 1 2
CCDC150 WILD-TYPE 44 41 16 29 32 30 44
'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 0.51

Table S1391.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CCDC150 MUTATED 0 0 5 4 1
CCDC150 WILD-TYPE 41 40 59 71 19
'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.918 (Fisher's exact test), Q value = 1

Table S1392.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CCDC150 MUTATED 4 2 4
CCDC150 WILD-TYPE 100 53 77
'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.607 (Fisher's exact test), Q value = 0.91

Table S1393.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CCDC150 MUTATED 0 2 1 3
CCDC150 WILD-TYPE 14 45 20 27
'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.66 (Fisher's exact test), Q value = 0.95

Table S1394.  Gene #128: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CCDC150 MUTATED 2 2 2
CCDC150 WILD-TYPE 32 51 23
'KIF21A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S1395.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
KIF21A MUTATED 1 2 0 0
KIF21A WILD-TYPE 12 16 13 7
'KIF21A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 0.53

Table S1396.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
KIF21A MUTATED 2 0 1 0 0
KIF21A WILD-TYPE 10 10 6 7 15
'KIF21A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0022 (Fisher's exact test), Q value = 0.037

Table S1397.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
KIF21A MUTATED 0 11 4 0
KIF21A WILD-TYPE 71 76 50 30

Figure S331.  Get High-res Image Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'KIF21A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.63

Table S1398.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
KIF21A MUTATED 1 1 6
KIF21A WILD-TYPE 43 27 57
'KIF21A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0674 (Fisher's exact test), Q value = 0.31

Table S1399.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
KIF21A MUTATED 1 0 3 3 3 3 1
KIF21A WILD-TYPE 23 50 28 16 19 30 23
'KIF21A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.581 (Fisher's exact test), Q value = 0.89

Table S1400.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
KIF21A MUTATED 4 5 4 1
KIF21A WILD-TYPE 64 73 27 25
'KIF21A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.65

Table S1401.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
KIF21A MUTATED 2 6 4 3
KIF21A WILD-TYPE 62 67 32 71
'KIF21A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00091 (Fisher's exact test), Q value = 0.022

Table S1402.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
KIF21A MUTATED 1 0 0 5 7 1 1
KIF21A WILD-TYPE 43 41 17 28 28 30 45

Figure S332.  Get High-res Image Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'KIF21A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S1403.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
KIF21A MUTATED 2 1 6 4 1
KIF21A WILD-TYPE 39 39 58 71 19
'KIF21A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 0.61

Table S1404.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
KIF21A MUTATED 9 1 4
KIF21A WILD-TYPE 95 54 77
'KIF21A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S1405.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
KIF21A MUTATED 0 2 0 2
KIF21A WILD-TYPE 14 45 21 28
'KIF21A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 0.87

Table S1406.  Gene #129: 'KIF21A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
KIF21A MUTATED 2 1 1
KIF21A WILD-TYPE 32 52 24
'BHLHB9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0804 (Fisher's exact test), Q value = 0.33

Table S1407.  Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
BHLHB9 MUTATED 0 6 1 1
BHLHB9 WILD-TYPE 71 81 53 29
'BHLHB9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1408.  Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
BHLHB9 MUTATED 1 1 2
BHLHB9 WILD-TYPE 43 27 61
'BHLHB9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S1409.  Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
BHLHB9 MUTATED 0 1 1 1 1 1 2
BHLHB9 WILD-TYPE 24 49 30 18 21 32 22
'BHLHB9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 0.6

Table S1410.  Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
BHLHB9 MUTATED 1 2 2 2
BHLHB9 WILD-TYPE 67 76 29 24
'BHLHB9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.128 (Fisher's exact test), Q value = 0.43

Table S1411.  Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
BHLHB9 MUTATED 2 4 2 0
BHLHB9 WILD-TYPE 62 69 34 74
'BHLHB9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0362 (Fisher's exact test), Q value = 0.23

Table S1412.  Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
BHLHB9 MUTATED 1 0 1 3 3 0 0
BHLHB9 WILD-TYPE 43 41 16 30 32 31 46

Figure S333.  Get High-res Image Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'BHLHB9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00355 (Fisher's exact test), Q value = 0.05

Table S1413.  Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
BHLHB9 MUTATED 0 1 7 0 0
BHLHB9 WILD-TYPE 41 39 57 75 20

Figure S334.  Get High-res Image Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'BHLHB9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.071 (Fisher's exact test), Q value = 0.32

Table S1414.  Gene #130: 'BHLHB9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
BHLHB9 MUTATED 6 2 0
BHLHB9 WILD-TYPE 98 53 81
'EXOSC9 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S1415.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
EXOSC9 MUTATED 1 2 0 0
EXOSC9 WILD-TYPE 12 16 13 7
'EXOSC9 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.53

Table S1416.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
EXOSC9 MUTATED 2 0 1 0 0
EXOSC9 WILD-TYPE 10 10 6 7 15
'EXOSC9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0312 (Fisher's exact test), Q value = 0.21

Table S1417.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
EXOSC9 MUTATED 0 7 3 0
EXOSC9 WILD-TYPE 71 80 51 30

Figure S335.  Get High-res Image Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'EXOSC9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 0.65

Table S1418.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
EXOSC9 MUTATED 0 0 3
EXOSC9 WILD-TYPE 44 28 60
'EXOSC9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S1419.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
EXOSC9 MUTATED 1 1 1 1 2 1 1
EXOSC9 WILD-TYPE 23 49 30 18 20 32 23
'EXOSC9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S1420.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
EXOSC9 MUTATED 3 2 2 1
EXOSC9 WILD-TYPE 65 76 29 25
'EXOSC9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.65

Table S1421.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
EXOSC9 MUTATED 1 4 3 2
EXOSC9 WILD-TYPE 63 69 33 72
'EXOSC9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0016 (Fisher's exact test), Q value = 0.031

Table S1422.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
EXOSC9 MUTATED 0 0 0 4 5 0 1
EXOSC9 WILD-TYPE 44 41 17 29 30 31 45

Figure S336.  Get High-res Image Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'EXOSC9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 0.68

Table S1423.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
EXOSC9 MUTATED 0 1 5 3 0
EXOSC9 WILD-TYPE 41 39 59 72 20
'EXOSC9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S1424.  Gene #131: 'EXOSC9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
EXOSC9 MUTATED 5 1 3
EXOSC9 WILD-TYPE 99 54 78
'ZKSCAN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00581 (Fisher's exact test), Q value = 0.068

Table S1425.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZKSCAN1 MUTATED 0 7 0 0
ZKSCAN1 WILD-TYPE 71 80 54 30

Figure S337.  Get High-res Image Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZKSCAN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 0.98

Table S1426.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZKSCAN1 MUTATED 2 0 3
ZKSCAN1 WILD-TYPE 42 28 60
'ZKSCAN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S1427.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZKSCAN1 MUTATED 0 2 2 0 0 2 1
ZKSCAN1 WILD-TYPE 24 48 29 19 22 31 23
'ZKSCAN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.166 (Fisher's exact test), Q value = 0.48

Table S1428.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZKSCAN1 MUTATED 2 1 3 1
ZKSCAN1 WILD-TYPE 66 77 28 25
'ZKSCAN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0151 (Fisher's exact test), Q value = 0.13

Table S1429.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZKSCAN1 MUTATED 0 2 4 1
ZKSCAN1 WILD-TYPE 64 71 32 73

Figure S338.  Get High-res Image Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ZKSCAN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0244 (Fisher's exact test), Q value = 0.18

Table S1430.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZKSCAN1 MUTATED 0 0 2 3 1 0 1
ZKSCAN1 WILD-TYPE 44 41 15 30 34 31 45

Figure S339.  Get High-res Image Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZKSCAN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0286 (Fisher's exact test), Q value = 0.2

Table S1431.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZKSCAN1 MUTATED 0 0 6 1 0
ZKSCAN1 WILD-TYPE 41 40 58 74 20

Figure S340.  Get High-res Image Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ZKSCAN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.338 (Fisher's exact test), Q value = 0.68

Table S1432.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZKSCAN1 MUTATED 3 3 1
ZKSCAN1 WILD-TYPE 101 52 80
'ZKSCAN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.255 (Fisher's exact test), Q value = 0.61

Table S1433.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZKSCAN1 MUTATED 0 1 0 3
ZKSCAN1 WILD-TYPE 14 46 21 27
'ZKSCAN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 0.87

Table S1434.  Gene #132: 'ZKSCAN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZKSCAN1 MUTATED 2 1 1
ZKSCAN1 WILD-TYPE 32 52 24
'OR8B8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 0.43

Table S1435.  Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
OR8B8 MUTATED 0 5 2 0
OR8B8 WILD-TYPE 71 82 52 30
'OR8B8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1436.  Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
OR8B8 MUTATED 1 0 2
OR8B8 WILD-TYPE 43 28 61
'OR8B8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 0.72

Table S1437.  Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
OR8B8 MUTATED 1 0 2 1 1 1 0
OR8B8 WILD-TYPE 23 50 29 18 21 32 24
'OR8B8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.419 (Fisher's exact test), Q value = 0.76

Table S1438.  Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
OR8B8 MUTATED 1 3 2 0
OR8B8 WILD-TYPE 67 75 29 26
'OR8B8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 0.88

Table S1439.  Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
OR8B8 MUTATED 2 2 2 1
OR8B8 WILD-TYPE 62 71 34 73
'OR8B8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00489 (Fisher's exact test), Q value = 0.062

Table S1440.  Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
OR8B8 MUTATED 0 0 2 2 3 0 0
OR8B8 WILD-TYPE 44 41 15 31 32 31 46

Figure S341.  Get High-res Image Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'OR8B8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 0.85

Table S1441.  Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
OR8B8 MUTATED 1 1 4 1 0
OR8B8 WILD-TYPE 40 39 60 74 20
'OR8B8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.611 (Fisher's exact test), Q value = 0.91

Table S1442.  Gene #133: 'OR8B8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
OR8B8 MUTATED 4 2 1
OR8B8 WILD-TYPE 100 53 80
'SENP7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.356 (Fisher's exact test), Q value = 0.7

Table S1443.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
SENP7 MUTATED 2 3 0 0
SENP7 WILD-TYPE 11 15 13 7
'SENP7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0352 (Fisher's exact test), Q value = 0.22

Table S1444.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
SENP7 MUTATED 3 0 0 2 0
SENP7 WILD-TYPE 9 10 7 5 15

Figure S342.  Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'SENP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0179 (Fisher's exact test), Q value = 0.14

Table S1445.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SENP7 MUTATED 0 9 2 1
SENP7 WILD-TYPE 71 78 52 29

Figure S343.  Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SENP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 0.98

Table S1446.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SENP7 MUTATED 2 0 3
SENP7 WILD-TYPE 42 28 60
'SENP7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S1447.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SENP7 MUTATED 0 3 3 1 2 1 1
SENP7 WILD-TYPE 24 47 28 18 20 32 23
'SENP7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.665 (Fisher's exact test), Q value = 0.95

Table S1448.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SENP7 MUTATED 2 6 2 1
SENP7 WILD-TYPE 66 72 29 25
'SENP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.035 (Fisher's exact test), Q value = 0.22

Table S1449.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SENP7 MUTATED 3 6 3 0
SENP7 WILD-TYPE 61 67 33 74

Figure S344.  Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SENP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 5e-05 (Fisher's exact test), Q value = 0.0027

Table S1450.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SENP7 MUTATED 0 0 1 5 6 0 0
SENP7 WILD-TYPE 44 41 16 28 29 31 46

Figure S345.  Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SENP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.02 (Fisher's exact test), Q value = 0.15

Table S1451.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SENP7 MUTATED 1 2 7 0 1
SENP7 WILD-TYPE 40 38 57 75 19

Figure S346.  Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'SENP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0453 (Fisher's exact test), Q value = 0.25

Table S1452.  Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SENP7 MUTATED 9 1 1
SENP7 WILD-TYPE 95 54 80

Figure S347.  Get High-res Image Gene #134: 'SENP7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'WDR65 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 0.41

Table S1453.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
WDR65 MUTATED 0 5 1 0
WDR65 WILD-TYPE 71 82 53 30
'WDR65 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S1454.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
WDR65 MUTATED 1 1 3
WDR65 WILD-TYPE 43 27 60
'WDR65 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.51

Table S1455.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
WDR65 MUTATED 1 0 3 0 1 1 0
WDR65 WILD-TYPE 23 50 28 19 21 32 24
'WDR65 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.611 (Fisher's exact test), Q value = 0.91

Table S1456.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
WDR65 MUTATED 2 2 2 0
WDR65 WILD-TYPE 66 76 29 26
'WDR65 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 0.99

Table S1457.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
WDR65 MUTATED 1 3 0 2
WDR65 WILD-TYPE 63 70 36 72
'WDR65 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0889 (Fisher's exact test), Q value = 0.36

Table S1458.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
WDR65 MUTATED 0 0 0 2 3 0 1
WDR65 WILD-TYPE 44 41 17 31 32 31 45
'WDR65 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S1459.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
WDR65 MUTATED 1 1 1 2 1
WDR65 WILD-TYPE 40 39 63 73 19
'WDR65 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.435 (Fisher's exact test), Q value = 0.77

Table S1460.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
WDR65 MUTATED 4 0 2
WDR65 WILD-TYPE 100 55 79
'WDR65 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.729 (Fisher's exact test), Q value = 0.99

Table S1461.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
WDR65 MUTATED 0 2 1 0
WDR65 WILD-TYPE 14 45 20 30
'WDR65 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1462.  Gene #135: 'WDR65 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
WDR65 MUTATED 1 1 1
WDR65 WILD-TYPE 33 52 24
'NRIP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 0.83

Table S1463.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
NRIP1 MUTATED 2 1 0 0
NRIP1 WILD-TYPE 11 17 13 7
'NRIP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0778 (Fisher's exact test), Q value = 0.33

Table S1464.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
NRIP1 MUTATED 1 0 0 2 0
NRIP1 WILD-TYPE 11 10 7 5 15
'NRIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0881 (Fisher's exact test), Q value = 0.36

Table S1465.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NRIP1 MUTATED 1 9 2 1
NRIP1 WILD-TYPE 70 78 52 29
'NRIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S1466.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
NRIP1 MUTATED 3 1 3
NRIP1 WILD-TYPE 41 27 60
'NRIP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 0.53

Table S1467.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NRIP1 MUTATED 1 2 5 0 1 3 0
NRIP1 WILD-TYPE 23 48 26 19 21 30 24
'NRIP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.22 (Fisher's exact test), Q value = 0.55

Table S1468.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NRIP1 MUTATED 3 5 4 0
NRIP1 WILD-TYPE 65 73 27 26
'NRIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.527 (Fisher's exact test), Q value = 0.85

Table S1469.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NRIP1 MUTATED 3 6 2 2
NRIP1 WILD-TYPE 61 67 34 72
'NRIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00053 (Fisher's exact test), Q value = 0.016

Table S1470.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NRIP1 MUTATED 0 0 2 5 5 0 1
NRIP1 WILD-TYPE 44 41 15 28 30 31 45

Figure S348.  Get High-res Image Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NRIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 0.63

Table S1471.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NRIP1 MUTATED 2 1 7 2 1
NRIP1 WILD-TYPE 39 39 57 73 19
'NRIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.63

Table S1472.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NRIP1 MUTATED 8 3 2
NRIP1 WILD-TYPE 96 52 79
'NRIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S1473.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
NRIP1 MUTATED 0 2 1 2
NRIP1 WILD-TYPE 14 45 20 28
'NRIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 0.65

Table S1474.  Gene #136: 'NRIP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
NRIP1 MUTATED 3 1 1
NRIP1 WILD-TYPE 31 52 24
'MCTP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.504 (Fisher's exact test), Q value = 0.83

Table S1475.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MCTP1 MUTATED 2 1 0 0
MCTP1 WILD-TYPE 11 17 13 7
'MCTP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.226 (Fisher's exact test), Q value = 0.57

Table S1476.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MCTP1 MUTATED 0 1 1 1 0
MCTP1 WILD-TYPE 12 9 6 6 15
'MCTP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0493 (Fisher's exact test), Q value = 0.26

Table S1477.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MCTP1 MUTATED 1 9 1 2
MCTP1 WILD-TYPE 70 78 53 28

Figure S349.  Get High-res Image Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MCTP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S1478.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MCTP1 MUTATED 3 1 2
MCTP1 WILD-TYPE 41 27 61
'MCTP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S1479.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MCTP1 MUTATED 1 3 2 1 1 3 0
MCTP1 WILD-TYPE 23 47 29 18 21 30 24
'MCTP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.73 (Fisher's exact test), Q value = 0.99

Table S1480.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MCTP1 MUTATED 4 5 2 0
MCTP1 WILD-TYPE 64 73 29 26
'MCTP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S1481.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MCTP1 MUTATED 4 4 2 3
MCTP1 WILD-TYPE 60 69 34 71
'MCTP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0218 (Fisher's exact test), Q value = 0.16

Table S1482.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MCTP1 MUTATED 1 0 1 5 4 0 2
MCTP1 WILD-TYPE 43 41 16 28 31 31 44

Figure S350.  Get High-res Image Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MCTP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 0.46

Table S1483.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MCTP1 MUTATED 0 1 6 3 2
MCTP1 WILD-TYPE 41 39 58 72 18
'MCTP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.693 (Fisher's exact test), Q value = 0.97

Table S1484.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MCTP1 MUTATED 7 2 3
MCTP1 WILD-TYPE 97 53 78
'MCTP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 0.76

Table S1485.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MCTP1 MUTATED 0 1 2 1
MCTP1 WILD-TYPE 14 46 19 29
'MCTP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0928 (Fisher's exact test), Q value = 0.36

Table S1486.  Gene #137: 'MCTP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MCTP1 MUTATED 2 0 2
MCTP1 WILD-TYPE 32 53 23
'CCDC146 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1487.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CCDC146 MUTATED 1 2 1 0
CCDC146 WILD-TYPE 12 16 12 7
'CCDC146 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0479 (Fisher's exact test), Q value = 0.26

Table S1488.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CCDC146 MUTATED 2 0 2 0 0
CCDC146 WILD-TYPE 10 10 5 7 15

Figure S351.  Get High-res Image Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CCDC146 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00149 (Fisher's exact test), Q value = 0.029

Table S1489.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CCDC146 MUTATED 0 11 3 0
CCDC146 WILD-TYPE 71 76 51 30

Figure S352.  Get High-res Image Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CCDC146 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1490.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CCDC146 MUTATED 2 1 4
CCDC146 WILD-TYPE 42 27 59
'CCDC146 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.61

Table S1491.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CCDC146 MUTATED 1 1 4 2 2 2 0
CCDC146 WILD-TYPE 23 49 27 17 20 31 24
'CCDC146 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 0.7

Table S1492.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CCDC146 MUTATED 3 6 3 0
CCDC146 WILD-TYPE 65 72 28 26
'CCDC146 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.358 (Fisher's exact test), Q value = 0.7

Table S1493.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CCDC146 MUTATED 2 5 4 3
CCDC146 WILD-TYPE 62 68 32 71
'CCDC146 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00099 (Fisher's exact test), Q value = 0.023

Table S1494.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CCDC146 MUTATED 0 0 1 5 6 1 1
CCDC146 WILD-TYPE 44 41 16 28 29 30 45

Figure S353.  Get High-res Image Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC146 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 0.37

Table S1495.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CCDC146 MUTATED 1 1 8 2 1
CCDC146 WILD-TYPE 40 39 56 73 19
'CCDC146 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 0.51

Table S1496.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CCDC146 MUTATED 9 2 2
CCDC146 WILD-TYPE 95 53 79
'CCDC146 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S1497.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CCDC146 MUTATED 0 2 1 2
CCDC146 WILD-TYPE 14 45 20 28
'CCDC146 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 0.77

Table S1498.  Gene #138: 'CCDC146 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CCDC146 MUTATED 2 1 2
CCDC146 WILD-TYPE 32 52 23
'ZNF620 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 0.38

Table S1499.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF620 MUTATED 1 7 1 0
ZNF620 WILD-TYPE 70 80 53 30
'ZNF620 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1500.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF620 MUTATED 2 1 2
ZNF620 WILD-TYPE 42 27 61
'ZNF620 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0367 (Fisher's exact test), Q value = 0.23

Table S1501.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF620 MUTATED 1 0 5 0 1 1 1
ZNF620 WILD-TYPE 23 50 26 19 21 32 23

Figure S354.  Get High-res Image Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'ZNF620 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.416 (Fisher's exact test), Q value = 0.76

Table S1502.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF620 MUTATED 1 5 2 1
ZNF620 WILD-TYPE 67 73 29 25
'ZNF620 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.449 (Fisher's exact test), Q value = 0.78

Table S1503.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF620 MUTATED 2 4 2 1
ZNF620 WILD-TYPE 62 69 34 73
'ZNF620 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0617 (Fisher's exact test), Q value = 0.3

Table S1504.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF620 MUTATED 1 0 1 2 4 1 0
ZNF620 WILD-TYPE 43 41 16 31 31 30 46
'ZNF620 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.91 (Fisher's exact test), Q value = 1

Table S1505.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF620 MUTATED 1 1 3 2 1
ZNF620 WILD-TYPE 40 39 61 73 19
'ZNF620 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.378 (Fisher's exact test), Q value = 0.72

Table S1506.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF620 MUTATED 4 3 1
ZNF620 WILD-TYPE 100 52 80
'ZNF620 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 0.95

Table S1507.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF620 MUTATED 0 1 1 2
ZNF620 WILD-TYPE 14 46 20 28
'ZNF620 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0662 (Fisher's exact test), Q value = 0.31

Table S1508.  Gene #139: 'ZNF620 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF620 MUTATED 3 0 1
ZNF620 WILD-TYPE 31 53 24
'PTPN12 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 0.39

Table S1509.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PTPN12 MUTATED 3 0 1 0
PTPN12 WILD-TYPE 10 18 12 7
'PTPN12 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 0.47

Table S1510.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PTPN12 MUTATED 0 0 2 1 1
PTPN12 WILD-TYPE 12 10 5 6 14
'PTPN12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0786 (Fisher's exact test), Q value = 0.33

Table S1511.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PTPN12 MUTATED 0 6 2 2
PTPN12 WILD-TYPE 71 81 52 28
'PTPN12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1512.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PTPN12 MUTATED 1 0 2
PTPN12 WILD-TYPE 43 28 61
'PTPN12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 0.65

Table S1513.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PTPN12 MUTATED 2 1 4 1 0 1 1
PTPN12 WILD-TYPE 22 49 27 18 22 32 23
'PTPN12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S1514.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PTPN12 MUTATED 4 3 2 1
PTPN12 WILD-TYPE 64 75 29 25
'PTPN12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0344 (Fisher's exact test), Q value = 0.22

Table S1515.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PTPN12 MUTATED 0 4 4 2
PTPN12 WILD-TYPE 64 69 32 72

Figure S355.  Get High-res Image Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PTPN12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0145 (Fisher's exact test), Q value = 0.13

Table S1516.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PTPN12 MUTATED 0 0 1 2 5 0 2
PTPN12 WILD-TYPE 44 41 16 31 30 31 44

Figure S356.  Get High-res Image Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PTPN12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 0.95

Table S1517.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PTPN12 MUTATED 1 1 5 3 0
PTPN12 WILD-TYPE 40 39 59 72 20
'PTPN12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S1518.  Gene #140: 'PTPN12 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PTPN12 MUTATED 4 3 3
PTPN12 WILD-TYPE 100 52 78
'RIOK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0588 (Fisher's exact test), Q value = 0.29

Table S1519.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RIOK3 MUTATED 0 6 3 0
RIOK3 WILD-TYPE 71 81 51 30
'RIOK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S1520.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RIOK3 MUTATED 1 1 4
RIOK3 WILD-TYPE 43 27 59
'RIOK3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 0.98

Table S1521.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RIOK3 MUTATED 1 1 1 1 2 2 0
RIOK3 WILD-TYPE 23 49 30 18 20 31 24
'RIOK3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S1522.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RIOK3 MUTATED 3 4 1 0
RIOK3 WILD-TYPE 65 74 30 26
'RIOK3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 0.66

Table S1523.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RIOK3 MUTATED 1 3 3 2
RIOK3 WILD-TYPE 63 70 33 72
'RIOK3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0149 (Fisher's exact test), Q value = 0.13

Table S1524.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RIOK3 MUTATED 0 0 1 3 4 0 1
RIOK3 WILD-TYPE 44 41 16 30 31 31 45

Figure S357.  Get High-res Image Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RIOK3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.64

Table S1525.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RIOK3 MUTATED 1 0 5 2 0
RIOK3 WILD-TYPE 40 40 59 73 20
'RIOK3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.653 (Fisher's exact test), Q value = 0.95

Table S1526.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RIOK3 MUTATED 5 1 2
RIOK3 WILD-TYPE 99 54 79
'RIOK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S1527.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RIOK3 MUTATED 0 2 0 2
RIOK3 WILD-TYPE 14 45 21 28
'RIOK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.557 (Fisher's exact test), Q value = 0.87

Table S1528.  Gene #141: 'RIOK3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RIOK3 MUTATED 2 1 1
RIOK3 WILD-TYPE 32 52 24
'CASP8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.504 (Fisher's exact test), Q value = 0.83

Table S1529.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CASP8 MUTATED 2 1 0 0
CASP8 WILD-TYPE 11 17 13 7
'CASP8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.077 (Fisher's exact test), Q value = 0.33

Table S1530.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CASP8 MUTATED 1 0 2 0 0
CASP8 WILD-TYPE 11 10 5 7 15
'CASP8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0068 (Fisher's exact test), Q value = 0.077

Table S1531.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CASP8 MUTATED 1 12 4 0
CASP8 WILD-TYPE 70 75 50 30

Figure S358.  Get High-res Image Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CASP8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 0.86

Table S1532.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CASP8 MUTATED 2 1 6
CASP8 WILD-TYPE 42 27 57
'CASP8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.61

Table S1533.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CASP8 MUTATED 3 1 3 3 3 2 1
CASP8 WILD-TYPE 21 49 28 16 19 31 23
'CASP8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 0.96

Table S1534.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CASP8 MUTATED 4 8 3 1
CASP8 WILD-TYPE 64 70 28 25
'CASP8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 0.71

Table S1535.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CASP8 MUTATED 3 5 5 4
CASP8 WILD-TYPE 61 68 31 70
'CASP8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00421 (Fisher's exact test), Q value = 0.057

Table S1536.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CASP8 MUTATED 0 1 3 3 7 1 2
CASP8 WILD-TYPE 44 40 14 30 28 30 44

Figure S359.  Get High-res Image Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CASP8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0178 (Fisher's exact test), Q value = 0.14

Table S1537.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CASP8 MUTATED 2 0 10 4 0
CASP8 WILD-TYPE 39 40 54 71 20

Figure S360.  Get High-res Image Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CASP8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 0.91

Table S1538.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CASP8 MUTATED 9 3 4
CASP8 WILD-TYPE 95 52 77
'CASP8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.61

Table S1539.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CASP8 MUTATED 0 3 0 4
CASP8 WILD-TYPE 14 44 21 26
'CASP8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 0.62

Table S1540.  Gene #142: 'CASP8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CASP8 MUTATED 4 2 1
CASP8 WILD-TYPE 30 51 24
'GFAP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 0.41

Table S1541.  Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
GFAP MUTATED 0 5 1 0
GFAP WILD-TYPE 71 82 53 30
'GFAP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S1542.  Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
GFAP MUTATED 2 0 2
GFAP WILD-TYPE 42 28 61
'GFAP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.47

Table S1543.  Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
GFAP MUTATED 0 0 3 1 0 1 1
GFAP WILD-TYPE 24 50 28 18 22 32 23
'GFAP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 0.53

Table S1544.  Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
GFAP MUTATED 0 4 1 1
GFAP WILD-TYPE 68 74 30 25
'GFAP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0513 (Fisher's exact test), Q value = 0.27

Table S1545.  Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
GFAP MUTATED 1 2 3 0
GFAP WILD-TYPE 63 71 33 74
'GFAP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0165 (Fisher's exact test), Q value = 0.14

Table S1546.  Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
GFAP MUTATED 0 0 1 3 2 0 0
GFAP WILD-TYPE 44 41 16 30 33 31 46

Figure S361.  Get High-res Image Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'GFAP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 0.6

Table S1547.  Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
GFAP MUTATED 1 1 3 0 1
GFAP WILD-TYPE 40 39 61 75 19
'GFAP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.109 (Fisher's exact test), Q value = 0.39

Table S1548.  Gene #143: 'GFAP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
GFAP MUTATED 5 1 0
GFAP WILD-TYPE 99 54 81
'OMA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0594 (Fisher's exact test), Q value = 0.29

Table S1549.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
OMA1 MUTATED 0 6 3 0
OMA1 WILD-TYPE 71 81 51 30
'OMA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S1550.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
OMA1 MUTATED 1 1 4
OMA1 WILD-TYPE 43 27 59
'OMA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 0.79

Table S1551.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
OMA1 MUTATED 1 1 3 2 0 1 1
OMA1 WILD-TYPE 23 49 28 17 22 32 23
'OMA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1552.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
OMA1 MUTATED 3 4 1 1
OMA1 WILD-TYPE 65 74 30 25
'OMA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.571 (Fisher's exact test), Q value = 0.88

Table S1553.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
OMA1 MUTATED 2 2 3 3
OMA1 WILD-TYPE 62 71 33 71
'OMA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0522 (Fisher's exact test), Q value = 0.27

Table S1554.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
OMA1 MUTATED 0 0 0 4 3 1 2
OMA1 WILD-TYPE 44 41 17 29 32 30 44
'OMA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S1555.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
OMA1 MUTATED 1 1 4 3 1
OMA1 WILD-TYPE 40 39 60 72 19
'OMA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.41

Table S1556.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
OMA1 MUTATED 7 0 3
OMA1 WILD-TYPE 97 55 78
'OMA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1557.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
OMA1 MUTATED 0 2 1 1
OMA1 WILD-TYPE 14 45 20 29
'OMA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.61

Table S1558.  Gene #144: 'OMA1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
OMA1 MUTATED 0 2 2
OMA1 WILD-TYPE 34 51 23
'DENND3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S1559.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
DENND3 MUTATED 2 1 0 0
DENND3 WILD-TYPE 11 17 13 7
'DENND3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.63

Table S1560.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
DENND3 MUTATED 1 0 1 1 0
DENND3 WILD-TYPE 11 10 6 6 15
'DENND3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00166 (Fisher's exact test), Q value = 0.032

Table S1561.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
DENND3 MUTATED 0 12 2 1
DENND3 WILD-TYPE 71 75 52 29

Figure S362.  Get High-res Image Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'DENND3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 0.81

Table S1562.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
DENND3 MUTATED 3 0 4
DENND3 WILD-TYPE 41 28 59
'DENND3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 0.66

Table S1563.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
DENND3 MUTATED 0 2 5 1 1 3 1
DENND3 WILD-TYPE 24 48 26 18 21 30 23
'DENND3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 0.58

Table S1564.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
DENND3 MUTATED 2 6 4 1
DENND3 WILD-TYPE 66 72 27 25
'DENND3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.121 (Fisher's exact test), Q value = 0.41

Table S1565.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
DENND3 MUTATED 2 7 4 2
DENND3 WILD-TYPE 62 66 32 72
'DENND3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.0015

Table S1566.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
DENND3 MUTATED 0 0 3 6 6 0 0
DENND3 WILD-TYPE 44 41 14 27 29 31 46

Figure S363.  Get High-res Image Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'DENND3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00486 (Fisher's exact test), Q value = 0.062

Table S1567.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
DENND3 MUTATED 1 1 10 1 2
DENND3 WILD-TYPE 40 39 54 74 18

Figure S364.  Get High-res Image Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'DENND3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.4 (Fisher's exact test), Q value = 0.75

Table S1568.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
DENND3 MUTATED 9 3 3
DENND3 WILD-TYPE 95 52 78
'DENND3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.4

Table S1569.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
DENND3 MUTATED 0 0 2 2
DENND3 WILD-TYPE 14 47 19 28
'DENND3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.561 (Fisher's exact test), Q value = 0.87

Table S1570.  Gene #145: 'DENND3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
DENND3 MUTATED 2 1 1
DENND3 WILD-TYPE 32 52 24
'CHEK2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S1571.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CHEK2 MUTATED 1 2 0 0
CHEK2 WILD-TYPE 12 16 13 7
'CHEK2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.53

Table S1572.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CHEK2 MUTATED 2 0 1 0 0
CHEK2 WILD-TYPE 10 10 6 7 15
'CHEK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0408 (Fisher's exact test), Q value = 0.24

Table S1573.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CHEK2 MUTATED 1 9 2 0
CHEK2 WILD-TYPE 70 78 52 30

Figure S365.  Get High-res Image Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CHEK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S1574.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CHEK2 MUTATED 1 1 4
CHEK2 WILD-TYPE 43 27 59
'CHEK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0122 (Fisher's exact test), Q value = 0.12

Table S1575.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CHEK2 MUTATED 1 0 4 2 2 0 0
CHEK2 WILD-TYPE 23 50 27 17 20 33 24

Figure S366.  Get High-res Image Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'CHEK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.143 (Fisher's exact test), Q value = 0.46

Table S1576.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CHEK2 MUTATED 1 5 3 0
CHEK2 WILD-TYPE 67 73 28 26
'CHEK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 0.99

Table S1577.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CHEK2 MUTATED 4 4 2 2
CHEK2 WILD-TYPE 60 69 34 72
'CHEK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00064 (Fisher's exact test), Q value = 0.017

Table S1578.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CHEK2 MUTATED 1 0 0 3 7 1 0
CHEK2 WILD-TYPE 43 41 17 30 28 30 46

Figure S367.  Get High-res Image Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CHEK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S1579.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CHEK2 MUTATED 1 2 4 3 1
CHEK2 WILD-TYPE 40 38 60 72 19
'CHEK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 0.69

Table S1580.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CHEK2 MUTATED 7 1 3
CHEK2 WILD-TYPE 97 54 78
'CHEK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1581.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CHEK2 MUTATED 0 2 1 1
CHEK2 WILD-TYPE 14 45 20 29
'CHEK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1582.  Gene #146: 'CHEK2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CHEK2 MUTATED 1 2 1
CHEK2 WILD-TYPE 33 51 24
'ZMYM2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S1583.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZMYM2 MUTATED 2 1 0 0
ZMYM2 WILD-TYPE 11 17 13 7
'ZMYM2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0774 (Fisher's exact test), Q value = 0.33

Table S1584.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZMYM2 MUTATED 1 0 0 2 0
ZMYM2 WILD-TYPE 11 10 7 5 15
'ZMYM2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00636 (Fisher's exact test), Q value = 0.073

Table S1585.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZMYM2 MUTATED 1 12 3 0
ZMYM2 WILD-TYPE 70 75 51 30

Figure S368.  Get High-res Image Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZMYM2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S1586.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZMYM2 MUTATED 4 1 4
ZMYM2 WILD-TYPE 40 27 59
'ZMYM2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 0.78

Table S1587.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZMYM2 MUTATED 1 2 5 1 2 1 1
ZMYM2 WILD-TYPE 23 48 26 18 20 32 23
'ZMYM2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.255 (Fisher's exact test), Q value = 0.61

Table S1588.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZMYM2 MUTATED 2 5 4 2
ZMYM2 WILD-TYPE 66 73 27 24
'ZMYM2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 0.7

Table S1589.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZMYM2 MUTATED 3 7 4 3
ZMYM2 WILD-TYPE 61 66 32 71
'ZMYM2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.019 (Fisher's exact test), Q value = 0.15

Table S1590.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZMYM2 MUTATED 1 1 2 5 6 1 1
ZMYM2 WILD-TYPE 43 40 15 28 29 30 45

Figure S369.  Get High-res Image Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.18 (Fisher's exact test), Q value = 0.51

Table S1591.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZMYM2 MUTATED 2 2 8 2 2
ZMYM2 WILD-TYPE 39 38 56 73 18
'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S1592.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZMYM2 MUTATED 8 4 4
ZMYM2 WILD-TYPE 96 51 77
'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.364 (Fisher's exact test), Q value = 0.7

Table S1593.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZMYM2 MUTATED 0 1 1 3
ZMYM2 WILD-TYPE 14 46 20 27
'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0193 (Fisher's exact test), Q value = 0.15

Table S1594.  Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZMYM2 MUTATED 4 0 1
ZMYM2 WILD-TYPE 30 53 24

Figure S370.  Get High-res Image Gene #147: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'EPC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 0.66

Table S1595.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
EPC2 MUTATED 0 3 2 0
EPC2 WILD-TYPE 71 84 52 30
'EPC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1596.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
EPC2 MUTATED 1 1 2
EPC2 WILD-TYPE 43 27 61
'EPC2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 0.69

Table S1597.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
EPC2 MUTATED 0 0 1 0 0 2 0
EPC2 WILD-TYPE 24 50 30 19 22 31 24
'EPC2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1598.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
EPC2 MUTATED 1 2 0 0
EPC2 WILD-TYPE 67 76 31 26
'EPC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 0.67

Table S1599.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
EPC2 MUTATED 1 0 1 3
EPC2 WILD-TYPE 63 73 35 71
'EPC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.184 (Fisher's exact test), Q value = 0.51

Table S1600.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
EPC2 MUTATED 0 0 1 0 1 2 1
EPC2 WILD-TYPE 44 41 16 33 34 29 45
'EPC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 0.92

Table S1601.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
EPC2 MUTATED 0 0 2 3 0
EPC2 WILD-TYPE 41 40 62 72 20
'EPC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 0.78

Table S1602.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
EPC2 MUTATED 1 1 3
EPC2 WILD-TYPE 103 54 78
'EPC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1603.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
EPC2 MUTATED 0 2 0 1
EPC2 WILD-TYPE 14 45 21 29
'EPC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 0.78

Table S1604.  Gene #148: 'EPC2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
EPC2 MUTATED 2 1 0
EPC2 WILD-TYPE 32 52 25
'DEPDC1B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S1605.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
DEPDC1B MUTATED 1 2 0 0
DEPDC1B WILD-TYPE 12 16 13 7
'DEPDC1B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.208 (Fisher's exact test), Q value = 0.54

Table S1606.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
DEPDC1B MUTATED 2 0 0 1 0
DEPDC1B WILD-TYPE 10 10 7 6 15
'DEPDC1B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00018 (Fisher's exact test), Q value = 0.0071

Table S1607.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
DEPDC1B MUTATED 0 11 0 0
DEPDC1B WILD-TYPE 71 76 54 30

Figure S371.  Get High-res Image Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'DEPDC1B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S1608.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
DEPDC1B MUTATED 3 1 2
DEPDC1B WILD-TYPE 41 27 61
'DEPDC1B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 0.97

Table S1609.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
DEPDC1B MUTATED 1 1 2 1 1 2 3
DEPDC1B WILD-TYPE 23 49 29 18 21 31 21
'DEPDC1B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.361 (Fisher's exact test), Q value = 0.7

Table S1610.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
DEPDC1B MUTATED 2 4 2 3
DEPDC1B WILD-TYPE 66 74 29 23
'DEPDC1B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0379 (Fisher's exact test), Q value = 0.23

Table S1611.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
DEPDC1B MUTATED 3 1 5 2
DEPDC1B WILD-TYPE 61 72 31 72

Figure S372.  Get High-res Image Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'DEPDC1B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.1 (Fisher's exact test), Q value = 0.37

Table S1612.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
DEPDC1B MUTATED 1 0 2 3 3 0 2
DEPDC1B WILD-TYPE 43 41 15 30 32 31 44
'DEPDC1B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 0.48

Table S1613.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
DEPDC1B MUTATED 0 1 6 2 1
DEPDC1B WILD-TYPE 41 39 58 73 19
'DEPDC1B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.372 (Fisher's exact test), Q value = 0.71

Table S1614.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
DEPDC1B MUTATED 4 4 2
DEPDC1B WILD-TYPE 100 51 79
'DEPDC1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0378 (Fisher's exact test), Q value = 0.23

Table S1615.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
DEPDC1B MUTATED 0 0 1 4
DEPDC1B WILD-TYPE 14 47 20 26

Figure S373.  Get High-res Image Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'DEPDC1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 0.65

Table S1616.  Gene #149: 'DEPDC1B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
DEPDC1B MUTATED 3 1 1
DEPDC1B WILD-TYPE 31 52 24
'C3AR1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 0.83

Table S1617.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
C3AR1 MUTATED 2 1 0 0
C3AR1 WILD-TYPE 11 17 13 7
'C3AR1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.63

Table S1618.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
C3AR1 MUTATED 1 0 1 1 0
C3AR1 WILD-TYPE 11 10 6 6 15
'C3AR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0255 (Fisher's exact test), Q value = 0.18

Table S1619.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
C3AR1 MUTATED 0 6 0 1
C3AR1 WILD-TYPE 71 81 54 29

Figure S374.  Get High-res Image Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'C3AR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.589 (Fisher's exact test), Q value = 0.89

Table S1620.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
C3AR1 MUTATED 0 2 2 1 1 0 0
C3AR1 WILD-TYPE 24 48 29 18 21 33 24
'C3AR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S1621.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
C3AR1 MUTATED 2 3 1 0
C3AR1 WILD-TYPE 66 75 30 26
'C3AR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.64

Table S1622.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
C3AR1 MUTATED 0 2 2 3
C3AR1 WILD-TYPE 64 71 34 71
'C3AR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 0.48

Table S1623.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
C3AR1 MUTATED 0 0 0 2 2 0 3
C3AR1 WILD-TYPE 44 41 17 31 33 31 43
'C3AR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 0.75

Table S1624.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
C3AR1 MUTATED 0 0 3 2 1
C3AR1 WILD-TYPE 41 40 61 73 19
'C3AR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1625.  Gene #150: 'C3AR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
C3AR1 MUTATED 3 1 2
C3AR1 WILD-TYPE 101 54 79
'STK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.385 (Fisher's exact test), Q value = 0.73

Table S1626.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
STK3 MUTATED 1 6 2 1
STK3 WILD-TYPE 70 81 52 29
'STK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 0.65

Table S1627.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
STK3 MUTATED 2 3 2
STK3 WILD-TYPE 42 25 61
'STK3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 0.81

Table S1628.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
STK3 MUTATED 1 1 3 1 0 2 0
STK3 WILD-TYPE 23 49 28 18 22 31 24
'STK3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.587 (Fisher's exact test), Q value = 0.89

Table S1629.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
STK3 MUTATED 2 5 1 0
STK3 WILD-TYPE 66 73 30 26
'STK3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.941 (Fisher's exact test), Q value = 1

Table S1630.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
STK3 MUTATED 2 4 1 3
STK3 WILD-TYPE 62 69 35 71
'STK3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0274 (Fisher's exact test), Q value = 0.19

Table S1631.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
STK3 MUTATED 0 0 1 3 4 0 2
STK3 WILD-TYPE 44 41 16 30 31 31 44

Figure S375.  Get High-res Image Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'STK3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.987 (Fisher's exact test), Q value = 1

Table S1632.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
STK3 MUTATED 1 2 3 3 1
STK3 WILD-TYPE 40 38 61 72 19
'STK3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.551 (Fisher's exact test), Q value = 0.87

Table S1633.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
STK3 MUTATED 6 1 3
STK3 WILD-TYPE 98 54 78
'STK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S1634.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
STK3 MUTATED 0 3 2 1
STK3 WILD-TYPE 14 44 19 29
'STK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.661 (Fisher's exact test), Q value = 0.95

Table S1635.  Gene #151: 'STK3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
STK3 MUTATED 2 2 2
STK3 WILD-TYPE 32 51 23
'FOXJ3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S1636.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
FOXJ3 MUTATED 2 1 0 0
FOXJ3 WILD-TYPE 11 17 13 7
'FOXJ3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.63

Table S1637.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
FOXJ3 MUTATED 1 0 1 1 0
FOXJ3 WILD-TYPE 11 10 6 6 15
'FOXJ3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0641 (Fisher's exact test), Q value = 0.31

Table S1638.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FOXJ3 MUTATED 0 7 2 1
FOXJ3 WILD-TYPE 71 80 52 29
'FOXJ3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1639.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
FOXJ3 MUTATED 1 0 2
FOXJ3 WILD-TYPE 43 28 61
'FOXJ3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 0.79

Table S1640.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FOXJ3 MUTATED 0 2 3 2 0 1 1
FOXJ3 WILD-TYPE 24 48 28 17 22 32 23
'FOXJ3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.921 (Fisher's exact test), Q value = 1

Table S1641.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FOXJ3 MUTATED 3 3 2 1
FOXJ3 WILD-TYPE 65 75 29 25
'FOXJ3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.044 (Fisher's exact test), Q value = 0.25

Table S1642.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FOXJ3 MUTATED 2 5 3 0
FOXJ3 WILD-TYPE 62 68 33 74

Figure S376.  Get High-res Image Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'FOXJ3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00444 (Fisher's exact test), Q value = 0.059

Table S1643.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FOXJ3 MUTATED 0 1 1 3 5 0 0
FOXJ3 WILD-TYPE 44 40 16 30 30 31 46

Figure S377.  Get High-res Image Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FOXJ3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0622 (Fisher's exact test), Q value = 0.3

Table S1644.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FOXJ3 MUTATED 0 1 7 2 0
FOXJ3 WILD-TYPE 41 39 57 73 20
'FOXJ3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 0.53

Table S1645.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FOXJ3 MUTATED 7 2 1
FOXJ3 WILD-TYPE 97 53 80
'FOXJ3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 0.38

Table S1646.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
FOXJ3 MUTATED 1 0 0 2
FOXJ3 WILD-TYPE 13 47 21 28
'FOXJ3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0358 (Fisher's exact test), Q value = 0.23

Table S1647.  Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
FOXJ3 MUTATED 3 0 0
FOXJ3 WILD-TYPE 31 53 25

Figure S378.  Get High-res Image Gene #152: 'FOXJ3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'EPS8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 0.73

Table S1648.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
EPS8 MUTATED 1 6 3 1
EPS8 WILD-TYPE 70 81 51 29
'EPS8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 0.75

Table S1649.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
EPS8 MUTATED 3 0 3
EPS8 WILD-TYPE 41 28 60
'EPS8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.976 (Fisher's exact test), Q value = 1

Table S1650.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
EPS8 MUTATED 2 2 2 1 1 1 1
EPS8 WILD-TYPE 22 48 29 18 21 32 23
'EPS8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S1651.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
EPS8 MUTATED 4 3 2 1
EPS8 WILD-TYPE 64 75 29 25
'EPS8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 0.97

Table S1652.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
EPS8 MUTATED 3 5 2 2
EPS8 WILD-TYPE 61 68 34 72
'EPS8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.171 (Fisher's exact test), Q value = 0.49

Table S1653.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
EPS8 MUTATED 1 2 1 4 3 1 0
EPS8 WILD-TYPE 43 39 16 29 32 30 46
'EPS8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S1654.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
EPS8 MUTATED 1 2 5 3 1
EPS8 WILD-TYPE 40 38 59 72 19
'EPS8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.278 (Fisher's exact test), Q value = 0.63

Table S1655.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
EPS8 MUTATED 8 2 2
EPS8 WILD-TYPE 96 53 79
'EPS8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S1656.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
EPS8 MUTATED 1 2 1 2
EPS8 WILD-TYPE 13 45 20 28
'EPS8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.61

Table S1657.  Gene #153: 'EPS8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
EPS8 MUTATED 3 1 2
EPS8 WILD-TYPE 31 52 23
'ZNF385B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0577 (Fisher's exact test), Q value = 0.29

Table S1658.  Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF385B MUTATED 0 6 1 0
ZNF385B WILD-TYPE 71 81 53 30
'ZNF385B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S1659.  Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF385B MUTATED 1 1 3
ZNF385B WILD-TYPE 43 27 60
'ZNF385B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0987 (Fisher's exact test), Q value = 0.37

Table S1660.  Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF385B MUTATED 0 0 3 0 2 1 1
ZNF385B WILD-TYPE 24 50 28 19 20 32 23
'ZNF385B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 0.83

Table S1661.  Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF385B MUTATED 1 3 2 1
ZNF385B WILD-TYPE 67 75 29 25
'ZNF385B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 0.77

Table S1662.  Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF385B MUTATED 1 3 2 1
ZNF385B WILD-TYPE 63 70 34 73
'ZNF385B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0267 (Fisher's exact test), Q value = 0.19

Table S1663.  Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF385B MUTATED 0 0 0 2 4 0 1
ZNF385B WILD-TYPE 44 41 17 31 31 31 45

Figure S379.  Get High-res Image Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF385B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 0.8

Table S1664.  Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF385B MUTATED 1 0 3 1 1
ZNF385B WILD-TYPE 40 40 61 74 19
'ZNF385B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.576 (Fisher's exact test), Q value = 0.88

Table S1665.  Gene #154: 'ZNF385B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF385B MUTATED 4 1 1
ZNF385B WILD-TYPE 100 54 80
'EFCAB4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 0.69

Table S1666.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
EFCAB4B MUTATED 1 5 4 1
EFCAB4B WILD-TYPE 70 82 50 29
'EFCAB4B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 0.82

Table S1667.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
EFCAB4B MUTATED 2 0 4
EFCAB4B WILD-TYPE 42 28 59
'EFCAB4B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.42

Table S1668.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
EFCAB4B MUTATED 1 3 4 2 0 0 0
EFCAB4B WILD-TYPE 23 47 27 17 22 33 24
'EFCAB4B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.585 (Fisher's exact test), Q value = 0.89

Table S1669.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
EFCAB4B MUTATED 3 6 1 0
EFCAB4B WILD-TYPE 65 72 30 26
'EFCAB4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S1670.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
EFCAB4B MUTATED 4 3 1 3
EFCAB4B WILD-TYPE 60 70 35 71
'EFCAB4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0546 (Fisher's exact test), Q value = 0.28

Table S1671.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
EFCAB4B MUTATED 0 1 0 4 4 1 1
EFCAB4B WILD-TYPE 44 40 17 29 31 30 45
'EFCAB4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.988 (Fisher's exact test), Q value = 1

Table S1672.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
EFCAB4B MUTATED 2 1 3 4 1
EFCAB4B WILD-TYPE 39 39 61 71 19
'EFCAB4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0678 (Fisher's exact test), Q value = 0.31

Table S1673.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
EFCAB4B MUTATED 8 0 3
EFCAB4B WILD-TYPE 96 55 78
'EFCAB4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 0.67

Table S1674.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
EFCAB4B MUTATED 0 2 2 0
EFCAB4B WILD-TYPE 14 45 19 30
'EFCAB4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0936 (Fisher's exact test), Q value = 0.36

Table S1675.  Gene #155: 'EFCAB4B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
EFCAB4B MUTATED 2 0 2
EFCAB4B WILD-TYPE 32 53 23
'NPRL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0542 (Fisher's exact test), Q value = 0.28

Table S1676.  Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NPRL2 MUTATED 0 3 0 2
NPRL2 WILD-TYPE 71 84 54 28
'NPRL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S1677.  Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NPRL2 MUTATED 0 1 1 1 0 1 0
NPRL2 WILD-TYPE 24 49 30 18 22 32 24
'NPRL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 0.47

Table S1678.  Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NPRL2 MUTATED 0 2 2 0
NPRL2 WILD-TYPE 68 76 29 26
'NPRL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1679.  Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NPRL2 MUTATED 1 2 0 2
NPRL2 WILD-TYPE 63 71 36 72
'NPRL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.536 (Fisher's exact test), Q value = 0.85

Table S1680.  Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NPRL2 MUTATED 0 0 0 1 2 1 1
NPRL2 WILD-TYPE 44 41 17 32 33 30 45
'NPRL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.649 (Fisher's exact test), Q value = 0.95

Table S1681.  Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NPRL2 MUTATED 0 2 1 2 0
NPRL2 WILD-TYPE 41 38 63 73 20
'NPRL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 0.92

Table S1682.  Gene #156: 'NPRL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NPRL2 MUTATED 3 0 2
NPRL2 WILD-TYPE 101 55 79
'ATF6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 0.76

Table S1683.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ATF6 MUTATED 3 1 2 0
ATF6 WILD-TYPE 10 17 11 7
'ATF6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.191 (Fisher's exact test), Q value = 0.52

Table S1684.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ATF6 MUTATED 1 0 2 2 1
ATF6 WILD-TYPE 11 10 5 5 14
'ATF6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0218 (Fisher's exact test), Q value = 0.16

Table S1685.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ATF6 MUTATED 0 8 3 3
ATF6 WILD-TYPE 71 79 51 27

Figure S380.  Get High-res Image Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ATF6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1686.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ATF6 MUTATED 2 1 3
ATF6 WILD-TYPE 42 27 60
'ATF6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.645 (Fisher's exact test), Q value = 0.94

Table S1687.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ATF6 MUTATED 1 2 3 2 1 3 0
ATF6 WILD-TYPE 23 48 28 17 21 30 24
'ATF6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 0.7

Table S1688.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ATF6 MUTATED 3 6 3 0
ATF6 WILD-TYPE 65 72 28 26
'ATF6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.074 (Fisher's exact test), Q value = 0.33

Table S1689.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ATF6 MUTATED 1 5 5 3
ATF6 WILD-TYPE 63 68 31 71
'ATF6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 0.47

Table S1690.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ATF6 MUTATED 0 1 2 3 4 2 2
ATF6 WILD-TYPE 44 40 15 30 31 29 44
'ATF6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 0.37

Table S1691.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ATF6 MUTATED 2 1 8 2 0
ATF6 WILD-TYPE 39 39 56 73 20
'ATF6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.287 (Fisher's exact test), Q value = 0.63

Table S1692.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ATF6 MUTATED 8 3 2
ATF6 WILD-TYPE 96 52 79
'ATF6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0954 (Fisher's exact test), Q value = 0.36

Table S1693.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ATF6 MUTATED 1 1 0 4
ATF6 WILD-TYPE 13 46 21 26
'ATF6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0995 (Fisher's exact test), Q value = 0.37

Table S1694.  Gene #157: 'ATF6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ATF6 MUTATED 4 1 1
ATF6 WILD-TYPE 30 52 24
'LIMA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 0.76

Table S1695.  Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
LIMA1 MUTATED 1 4 1 2
LIMA1 WILD-TYPE 70 83 53 28
'LIMA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 0.96

Table S1696.  Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
LIMA1 MUTATED 1 0 3
LIMA1 WILD-TYPE 43 28 60
'LIMA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.284 (Fisher's exact test), Q value = 0.63

Table S1697.  Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
LIMA1 MUTATED 1 1 4 0 0 1 1
LIMA1 WILD-TYPE 23 49 27 19 22 32 23
'LIMA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 0.84

Table S1698.  Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
LIMA1 MUTATED 1 4 2 1
LIMA1 WILD-TYPE 67 74 29 25
'LIMA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0022 (Fisher's exact test), Q value = 0.037

Table S1699.  Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
LIMA1 MUTATED 0 4 4 0
LIMA1 WILD-TYPE 64 69 32 74

Figure S381.  Get High-res Image Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'LIMA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00272 (Fisher's exact test), Q value = 0.042

Table S1700.  Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
LIMA1 MUTATED 0 0 1 4 3 0 0
LIMA1 WILD-TYPE 44 41 16 29 32 31 46

Figure S382.  Get High-res Image Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'LIMA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0321 (Fisher's exact test), Q value = 0.21

Table S1701.  Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
LIMA1 MUTATED 1 1 6 0 0
LIMA1 WILD-TYPE 40 39 58 75 20

Figure S383.  Get High-res Image Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'LIMA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0704 (Fisher's exact test), Q value = 0.32

Table S1702.  Gene #158: 'LIMA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
LIMA1 MUTATED 6 2 0
LIMA1 WILD-TYPE 98 53 81
'PPIG MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.65

Table S1703.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PPIG MUTATED 3 2 0 0
PPIG WILD-TYPE 10 16 13 7
'PPIG MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0925 (Fisher's exact test), Q value = 0.36

Table S1704.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PPIG MUTATED 2 0 1 2 0
PPIG WILD-TYPE 10 10 6 5 15
'PPIG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00036 (Fisher's exact test), Q value = 0.012

Table S1705.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PPIG MUTATED 0 13 1 2
PPIG WILD-TYPE 71 74 53 28

Figure S384.  Get High-res Image Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PPIG MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1706.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PPIG MUTATED 3 2 4
PPIG WILD-TYPE 41 26 59
'PPIG MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S1707.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PPIG MUTATED 2 2 3 2 2 2 2
PPIG WILD-TYPE 22 48 28 17 20 31 22
'PPIG MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.978 (Fisher's exact test), Q value = 1

Table S1708.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PPIG MUTATED 6 5 2 2
PPIG WILD-TYPE 62 73 29 24
'PPIG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.52

Table S1709.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PPIG MUTATED 3 7 4 2
PPIG WILD-TYPE 61 66 32 72
'PPIG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00252 (Fisher's exact test), Q value = 0.04

Table S1710.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PPIG MUTATED 1 1 1 7 5 0 1
PPIG WILD-TYPE 43 40 16 26 30 31 45

Figure S385.  Get High-res Image Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PPIG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0666 (Fisher's exact test), Q value = 0.31

Table S1711.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PPIG MUTATED 0 2 8 3 2
PPIG WILD-TYPE 41 38 56 72 18
'PPIG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 0.75

Table S1712.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PPIG MUTATED 9 3 3
PPIG WILD-TYPE 95 52 78
'PPIG MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 0.95

Table S1713.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PPIG MUTATED 1 2 2 3
PPIG WILD-TYPE 13 45 19 27
'PPIG MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0841 (Fisher's exact test), Q value = 0.34

Table S1714.  Gene #159: 'PPIG MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PPIG MUTATED 4 1 3
PPIG WILD-TYPE 30 52 22
'ZNF774 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0337 (Fisher's exact test), Q value = 0.22

Table S1715.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF774 MUTATED 1 6 0 3
ZNF774 WILD-TYPE 70 81 54 27

Figure S386.  Get High-res Image Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF774 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S1716.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF774 MUTATED 3 1 2
ZNF774 WILD-TYPE 41 27 61
'ZNF774 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.54

Table S1717.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF774 MUTATED 2 1 4 1 0 2 0
ZNF774 WILD-TYPE 22 49 27 18 22 31 24
'ZNF774 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 0.98

Table S1718.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF774 MUTATED 3 5 2 0
ZNF774 WILD-TYPE 65 73 29 26
'ZNF774 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 0.87

Table S1719.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF774 MUTATED 2 3 3 2
ZNF774 WILD-TYPE 62 70 33 72
'ZNF774 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.13 (Fisher's exact test), Q value = 0.43

Table S1720.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF774 MUTATED 1 0 1 4 2 0 2
ZNF774 WILD-TYPE 43 41 16 29 33 31 44
'ZNF774 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.583 (Fisher's exact test), Q value = 0.89

Table S1721.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF774 MUTATED 1 1 5 2 1
ZNF774 WILD-TYPE 40 39 59 73 19
'ZNF774 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 0.95

Table S1722.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF774 MUTATED 5 3 2
ZNF774 WILD-TYPE 99 52 79
'ZNF774 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S1723.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF774 MUTATED 1 2 1 2
ZNF774 WILD-TYPE 13 45 20 28
'ZNF774 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.155 (Fisher's exact test), Q value = 0.47

Table S1724.  Gene #160: 'ZNF774 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF774 MUTATED 2 1 3
ZNF774 WILD-TYPE 32 52 22
'MUTED MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0798 (Fisher's exact test), Q value = 0.33

Table S1725.  Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MUTED MUTATED 1 6 0 0
MUTED WILD-TYPE 70 81 54 30
'MUTED MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 0.78

Table S1726.  Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MUTED MUTATED 0 1 2
MUTED WILD-TYPE 44 27 61
'MUTED MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 0.96

Table S1727.  Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MUTED MUTATED 1 1 2 0 1 0 1
MUTED WILD-TYPE 23 49 29 19 21 33 23
'MUTED MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.374 (Fisher's exact test), Q value = 0.72

Table S1728.  Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MUTED MUTATED 2 1 2 1
MUTED WILD-TYPE 66 77 29 25
'MUTED MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 0.64

Table S1729.  Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MUTED MUTATED 0 2 2 3
MUTED WILD-TYPE 64 71 34 71
'MUTED MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.114 (Fisher's exact test), Q value = 0.4

Table S1730.  Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MUTED MUTATED 0 0 0 2 3 0 2
MUTED WILD-TYPE 44 41 17 31 32 31 44
'MUTED MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S1731.  Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MUTED MUTATED 0 1 2 3 0
MUTED WILD-TYPE 41 39 62 72 20
'MUTED MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S1732.  Gene #161: 'MUTED MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MUTED MUTATED 2 1 3
MUTED WILD-TYPE 102 54 78
'TPX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.41

Table S1733.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TPX2 MUTATED 0 5 1 0
TPX2 WILD-TYPE 71 82 53 30
'TPX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 0.86

Table S1734.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TPX2 MUTATED 2 1 1
TPX2 WILD-TYPE 42 27 62
'TPX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.46

Table S1735.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TPX2 MUTATED 0 0 3 1 0 1 1
TPX2 WILD-TYPE 24 50 28 18 22 32 23
'TPX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.53

Table S1736.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TPX2 MUTATED 0 4 1 1
TPX2 WILD-TYPE 68 74 30 25
'TPX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 0.6

Table S1737.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TPX2 MUTATED 2 2 2 0
TPX2 WILD-TYPE 62 71 34 74
'TPX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 0.47

Table S1738.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TPX2 MUTATED 1 0 1 2 2 0 0
TPX2 WILD-TYPE 43 41 16 31 33 31 46
'TPX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 0.6

Table S1739.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TPX2 MUTATED 1 1 3 0 1
TPX2 WILD-TYPE 40 39 61 75 19
'TPX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 0.44

Table S1740.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TPX2 MUTATED 4 2 0
TPX2 WILD-TYPE 100 53 81
'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.54

Table S1741.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
TPX2 MUTATED 0 0 1 2
TPX2 WILD-TYPE 14 47 20 28
'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.143 (Fisher's exact test), Q value = 0.46

Table S1742.  Gene #162: 'TPX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
TPX2 MUTATED 2 0 1
TPX2 WILD-TYPE 32 53 24
'PARG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0561 (Fisher's exact test), Q value = 0.28

Table S1743.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PARG MUTATED 0 6 1 2
PARG WILD-TYPE 71 81 53 28
'PARG MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1744.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PARG MUTATED 2 1 3
PARG WILD-TYPE 42 27 60
'PARG MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 0.92

Table S1745.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PARG MUTATED 0 2 3 1 1 1 0
PARG WILD-TYPE 24 48 28 18 21 32 24
'PARG MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.609 (Fisher's exact test), Q value = 0.91

Table S1746.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PARG MUTATED 2 4 2 0
PARG WILD-TYPE 66 74 29 26
'PARG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 0.71

Table S1747.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PARG MUTATED 2 5 1 1
PARG WILD-TYPE 62 68 35 73
'PARG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00848 (Fisher's exact test), Q value = 0.089

Table S1748.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PARG MUTATED 0 0 1 3 4 1 0
PARG WILD-TYPE 44 41 16 30 31 30 46

Figure S387.  Get High-res Image Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PARG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.66

Table S1749.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PARG MUTATED 1 1 5 1 1
PARG WILD-TYPE 40 39 59 74 19
'PARG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.63

Table S1750.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PARG MUTATED 6 2 1
PARG WILD-TYPE 98 53 80
'PARG MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.47

Table S1751.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PARG MUTATED 1 0 1 2
PARG WILD-TYPE 13 47 20 28
'PARG MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0927 (Fisher's exact test), Q value = 0.36

Table S1752.  Gene #163: 'PARG MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PARG MUTATED 2 0 2
PARG WILD-TYPE 32 53 23
'PSMD3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S1753.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
PSMD3 MUTATED 1 2 0 0
PSMD3 WILD-TYPE 12 16 13 7
'PSMD3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.53

Table S1754.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
PSMD3 MUTATED 2 0 0 1 0
PSMD3 WILD-TYPE 10 10 7 6 15
'PSMD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0898 (Fisher's exact test), Q value = 0.36

Table S1755.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PSMD3 MUTATED 0 5 4 1
PSMD3 WILD-TYPE 71 82 50 29
'PSMD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 0.77

Table S1756.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PSMD3 MUTATED 3 0 2
PSMD3 WILD-TYPE 41 28 61
'PSMD3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1757.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PSMD3 MUTATED 1 3 1 0 1 3 0
PSMD3 WILD-TYPE 23 47 30 19 21 30 24
'PSMD3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 0.74

Table S1758.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PSMD3 MUTATED 3 3 3 0
PSMD3 WILD-TYPE 65 75 28 26
'PSMD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 0.65

Table S1759.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PSMD3 MUTATED 3 4 3 1
PSMD3 WILD-TYPE 61 69 33 73
'PSMD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0178 (Fisher's exact test), Q value = 0.14

Table S1760.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PSMD3 MUTATED 0 2 3 3 1 2 0
PSMD3 WILD-TYPE 44 39 14 30 34 29 46

Figure S388.  Get High-res Image Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PSMD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0785 (Fisher's exact test), Q value = 0.33

Table S1761.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PSMD3 MUTATED 0 1 7 2 1
PSMD3 WILD-TYPE 41 39 57 73 19
'PSMD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.535 (Fisher's exact test), Q value = 0.85

Table S1762.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PSMD3 MUTATED 6 3 2
PSMD3 WILD-TYPE 98 52 79
'PSMD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.664 (Fisher's exact test), Q value = 0.95

Table S1763.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PSMD3 MUTATED 0 1 1 2
PSMD3 WILD-TYPE 14 46 20 28
'PSMD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.559 (Fisher's exact test), Q value = 0.87

Table S1764.  Gene #164: 'PSMD3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PSMD3 MUTATED 2 1 1
PSMD3 WILD-TYPE 32 52 24
'STRN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.051 (Fisher's exact test), Q value = 0.27

Table S1765.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
STRN3 MUTATED 1 9 1 1
STRN3 WILD-TYPE 70 78 53 29
'STRN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S1766.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
STRN3 MUTATED 3 1 3
STRN3 WILD-TYPE 41 27 60
'STRN3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 0.98

Table S1767.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
STRN3 MUTATED 1 2 4 1 2 1 1
STRN3 WILD-TYPE 23 48 27 18 20 32 23
'STRN3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 0.99

Table S1768.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
STRN3 MUTATED 3 5 3 1
STRN3 WILD-TYPE 65 73 28 25
'STRN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.245 (Fisher's exact test), Q value = 0.6

Table S1769.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
STRN3 MUTATED 3 5 3 1
STRN3 WILD-TYPE 61 68 33 73
'STRN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0497 (Fisher's exact test), Q value = 0.26

Table S1770.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
STRN3 MUTATED 2 0 1 4 4 0 1
STRN3 WILD-TYPE 42 41 16 29 31 31 45

Figure S389.  Get High-res Image Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'STRN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.39

Table S1771.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
STRN3 MUTATED 2 1 7 1 1
STRN3 WILD-TYPE 39 39 57 74 19
'STRN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 0.47

Table S1772.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
STRN3 MUTATED 7 4 1
STRN3 WILD-TYPE 97 51 80
'STRN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0768 (Fisher's exact test), Q value = 0.33

Table S1773.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
STRN3 MUTATED 1 0 1 3
STRN3 WILD-TYPE 13 47 20 27
'STRN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0291 (Fisher's exact test), Q value = 0.2

Table S1774.  Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
STRN3 MUTATED 2 0 3
STRN3 WILD-TYPE 32 53 22

Figure S390.  Get High-res Image Gene #165: 'STRN3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MLL4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.811 (Fisher's exact test), Q value = 1

Table S1775.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MLL4 MUTATED 2 1 1 0
MLL4 WILD-TYPE 11 17 12 7
'MLL4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0926 (Fisher's exact test), Q value = 0.36

Table S1776.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MLL4 MUTATED 1 0 2 1 0
MLL4 WILD-TYPE 11 10 5 6 15
'MLL4 MUTATION STATUS' versus 'CN_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0019

Table S1777.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MLL4 MUTATED 0 19 4 6
MLL4 WILD-TYPE 71 68 50 24

Figure S391.  Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MLL4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0286 (Fisher's exact test), Q value = 0.2

Table S1778.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MLL4 MUTATED 6 0 12
MLL4 WILD-TYPE 38 28 51

Figure S392.  Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'MLL4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.266 (Fisher's exact test), Q value = 0.62

Table S1779.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MLL4 MUTATED 2 3 6 1 1 6 1
MLL4 WILD-TYPE 22 47 25 18 21 27 23
'MLL4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.15 (Fisher's exact test), Q value = 0.46

Table S1780.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MLL4 MUTATED 4 9 6 1
MLL4 WILD-TYPE 64 69 25 25
'MLL4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0131 (Fisher's exact test), Q value = 0.12

Table S1781.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MLL4 MUTATED 3 8 10 9
MLL4 WILD-TYPE 61 65 26 65

Figure S393.  Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MLL4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00056 (Fisher's exact test), Q value = 0.016

Table S1782.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MLL4 MUTATED 0 2 2 10 6 6 4
MLL4 WILD-TYPE 44 39 15 23 29 25 42

Figure S394.  Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MLL4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00598 (Fisher's exact test), Q value = 0.07

Table S1783.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MLL4 MUTATED 1 1 12 9 5
MLL4 WILD-TYPE 40 39 52 66 15

Figure S395.  Get High-res Image Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'MLL4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.504 (Fisher's exact test), Q value = 0.83

Table S1784.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MLL4 MUTATED 13 4 11
MLL4 WILD-TYPE 91 51 70
'MLL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 0.58

Table S1785.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MLL4 MUTATED 0 5 5 4
MLL4 WILD-TYPE 14 42 16 26
'MLL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S1786.  Gene #166: 'MLL4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MLL4 MUTATED 5 6 3
MLL4 WILD-TYPE 29 47 22
'MSN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S1787.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MSN MUTATED 2 2 1 0
MSN WILD-TYPE 11 16 12 7
'MSN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 0.54

Table S1788.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MSN MUTATED 1 1 2 1 0
MSN WILD-TYPE 11 9 5 6 15
'MSN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.554 (Fisher's exact test), Q value = 0.87

Table S1789.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MSN MUTATED 3 8 2 2
MSN WILD-TYPE 68 79 52 28
'MSN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 0.51

Table S1790.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MSN MUTATED 4 1 1
MSN WILD-TYPE 40 27 62
'MSN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S1791.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MSN MUTATED 0 2 2 1 2 3 2
MSN WILD-TYPE 24 48 29 18 20 30 22
'MSN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 0.48

Table S1792.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MSN MUTATED 1 6 3 2
MSN WILD-TYPE 67 72 28 24
'MSN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.052 (Fisher's exact test), Q value = 0.27

Table S1793.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MSN MUTATED 5 4 5 1
MSN WILD-TYPE 59 69 31 73
'MSN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0283 (Fisher's exact test), Q value = 0.2

Table S1794.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MSN MUTATED 2 1 3 4 4 1 0
MSN WILD-TYPE 42 40 14 29 31 30 46

Figure S396.  Get High-res Image Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MSN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.46

Table S1795.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MSN MUTATED 2 2 7 1 1
MSN WILD-TYPE 39 38 57 74 19
'MSN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00978 (Fisher's exact test), Q value = 0.099

Table S1796.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MSN MUTATED 9 4 0
MSN WILD-TYPE 95 51 81

Figure S397.  Get High-res Image Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MSN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0729 (Fisher's exact test), Q value = 0.33

Table S1797.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MSN MUTATED 0 0 1 3
MSN WILD-TYPE 14 47 20 27
'MSN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.066 (Fisher's exact test), Q value = 0.31

Table S1798.  Gene #167: 'MSN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MSN MUTATED 3 0 1
MSN WILD-TYPE 31 53 24
'MAPK8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.622 (Fisher's exact test), Q value = 0.92

Table S1799.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MAPK8 MUTATED 2 1 2 0
MAPK8 WILD-TYPE 11 17 11 7
'MAPK8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 0.75

Table S1800.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MAPK8 MUTATED 1 0 1 2 1
MAPK8 WILD-TYPE 11 10 6 5 14
'MAPK8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 0.66

Table S1801.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MAPK8 MUTATED 1 6 2 2
MAPK8 WILD-TYPE 70 81 52 28
'MAPK8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 0.61

Table S1802.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MAPK8 MUTATED 3 0 1
MAPK8 WILD-TYPE 41 28 62
'MAPK8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 0.99

Table S1803.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MAPK8 MUTATED 2 1 1 1 1 2 0
MAPK8 WILD-TYPE 22 49 30 18 21 31 24
'MAPK8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 0.91

Table S1804.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MAPK8 MUTATED 2 4 2 0
MAPK8 WILD-TYPE 66 74 29 26
'MAPK8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.18 (Fisher's exact test), Q value = 0.51

Table S1805.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MAPK8 MUTATED 1 3 4 3
MAPK8 WILD-TYPE 63 70 32 71
'MAPK8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0426 (Fisher's exact test), Q value = 0.25

Table S1806.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MAPK8 MUTATED 0 0 2 3 3 2 1
MAPK8 WILD-TYPE 44 41 15 30 32 29 45

Figure S398.  Get High-res Image Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MAPK8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S1807.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MAPK8 MUTATED 1 2 4 2 1
MAPK8 WILD-TYPE 40 38 60 73 19
'MAPK8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 0.91

Table S1808.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MAPK8 MUTATED 6 2 2
MAPK8 WILD-TYPE 98 53 79
'MAPK8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 0.72

Table S1809.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MAPK8 MUTATED 1 1 0 2
MAPK8 WILD-TYPE 13 46 21 28
'MAPK8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0656 (Fisher's exact test), Q value = 0.31

Table S1810.  Gene #168: 'MAPK8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MAPK8 MUTATED 3 0 1
MAPK8 WILD-TYPE 31 53 24
'RBL2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.554 (Fisher's exact test), Q value = 0.87

Table S1811.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
RBL2 MUTATED 2 2 0 0
RBL2 WILD-TYPE 11 16 13 7
'RBL2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 0.6

Table S1812.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
RBL2 MUTATED 2 0 1 1 0
RBL2 WILD-TYPE 10 10 6 6 15
'RBL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0556 (Fisher's exact test), Q value = 0.28

Table S1813.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RBL2 MUTATED 0 7 3 2
RBL2 WILD-TYPE 71 80 51 28
'RBL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S1814.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RBL2 MUTATED 1 1 3
RBL2 WILD-TYPE 43 27 60
'RBL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.6

Table S1815.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RBL2 MUTATED 3 2 3 2 0 1 0
RBL2 WILD-TYPE 21 48 28 17 22 32 24
'RBL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.731 (Fisher's exact test), Q value = 0.99

Table S1816.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RBL2 MUTATED 4 5 2 0
RBL2 WILD-TYPE 64 73 29 26
'RBL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 0.97

Table S1817.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RBL2 MUTATED 3 5 2 2
RBL2 WILD-TYPE 61 68 34 72
'RBL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00187 (Fisher's exact test), Q value = 0.033

Table S1818.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RBL2 MUTATED 0 0 0 5 5 1 1
RBL2 WILD-TYPE 44 41 17 28 30 30 45

Figure S399.  Get High-res Image Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RBL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.53

Table S1819.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RBL2 MUTATED 1 1 7 2 1
RBL2 WILD-TYPE 40 39 57 73 19
'RBL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 0.41

Table S1820.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RBL2 MUTATED 9 1 2
RBL2 WILD-TYPE 95 54 79
'RBL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1821.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RBL2 MUTATED 0 2 1 1
RBL2 WILD-TYPE 14 45 20 29
'RBL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 0.61

Table S1822.  Gene #169: 'RBL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RBL2 MUTATED 0 2 2
RBL2 WILD-TYPE 34 51 23
'PDGFRA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 0.62

Table S1823.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PDGFRA MUTATED 1 7 3 1
PDGFRA WILD-TYPE 70 80 51 29
'PDGFRA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 0.83

Table S1824.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PDGFRA MUTATED 1 0 4
PDGFRA WILD-TYPE 43 28 59
'PDGFRA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.4

Table S1825.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PDGFRA MUTATED 2 1 4 0 2 0 1
PDGFRA WILD-TYPE 22 49 27 19 20 33 23
'PDGFRA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.552 (Fisher's exact test), Q value = 0.87

Table S1826.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PDGFRA MUTATED 2 4 3 1
PDGFRA WILD-TYPE 66 74 28 25
'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 0.77

Table S1827.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PDGFRA MUTATED 2 6 2 2
PDGFRA WILD-TYPE 62 67 34 72
'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00054 (Fisher's exact test), Q value = 0.016

Table S1828.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PDGFRA MUTATED 0 0 1 4 6 1 0
PDGFRA WILD-TYPE 44 41 16 29 29 30 46

Figure S400.  Get High-res Image Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 0.92

Table S1829.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PDGFRA MUTATED 1 2 5 2 1
PDGFRA WILD-TYPE 40 38 59 73 19
'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 0.76

Table S1830.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PDGFRA MUTATED 7 2 2
PDGFRA WILD-TYPE 97 53 79
'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S1831.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PDGFRA MUTATED 0 1 1 1
PDGFRA WILD-TYPE 14 46 20 29
'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1832.  Gene #170: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PDGFRA MUTATED 1 1 1
PDGFRA WILD-TYPE 33 52 24
'TMEM62 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0607 (Fisher's exact test), Q value = 0.3

Table S1833.  Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
TMEM62 MUTATED 0 6 3 0
TMEM62 WILD-TYPE 71 81 51 30
'TMEM62 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1834.  Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
TMEM62 MUTATED 1 0 2
TMEM62 WILD-TYPE 43 28 61
'TMEM62 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.475 (Fisher's exact test), Q value = 0.81

Table S1835.  Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
TMEM62 MUTATED 0 1 3 1 0 1 1
TMEM62 WILD-TYPE 24 49 28 18 22 32 23
'TMEM62 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1836.  Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
TMEM62 MUTATED 2 3 1 1
TMEM62 WILD-TYPE 66 75 30 25
'TMEM62 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 0.79

Table S1837.  Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
TMEM62 MUTATED 2 4 2 1
TMEM62 WILD-TYPE 62 69 34 73
'TMEM62 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0462 (Fisher's exact test), Q value = 0.26

Table S1838.  Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
TMEM62 MUTATED 0 1 0 4 3 0 1
TMEM62 WILD-TYPE 44 40 17 29 32 31 45

Figure S401.  Get High-res Image Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TMEM62 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 0.79

Table S1839.  Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
TMEM62 MUTATED 0 1 4 2 1
TMEM62 WILD-TYPE 41 39 60 73 19
'TMEM62 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 0.68

Table S1840.  Gene #171: 'TMEM62 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
TMEM62 MUTATED 5 0 3
TMEM62 WILD-TYPE 99 55 78
'RG9MTD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 0.66

Table S1841.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
RG9MTD3 MUTATED 2 5 0 1
RG9MTD3 WILD-TYPE 69 82 54 29
'RG9MTD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S1842.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
RG9MTD3 MUTATED 2 0 2
RG9MTD3 WILD-TYPE 42 28 61
'RG9MTD3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S1843.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
RG9MTD3 MUTATED 1 2 3 0 1 1 0
RG9MTD3 WILD-TYPE 23 48 28 19 21 32 24
'RG9MTD3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 0.65

Table S1844.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
RG9MTD3 MUTATED 2 3 3 0
RG9MTD3 WILD-TYPE 66 75 28 26
'RG9MTD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.58

Table S1845.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
RG9MTD3 MUTATED 2 5 0 1
RG9MTD3 WILD-TYPE 62 68 36 73
'RG9MTD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.037 (Fisher's exact test), Q value = 0.23

Table S1846.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
RG9MTD3 MUTATED 1 0 1 3 3 0 0
RG9MTD3 WILD-TYPE 43 41 16 30 32 31 46

Figure S402.  Get High-res Image Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RG9MTD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 0.84

Table S1847.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
RG9MTD3 MUTATED 2 1 4 1 0
RG9MTD3 WILD-TYPE 39 39 60 74 20
'RG9MTD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.588 (Fisher's exact test), Q value = 0.89

Table S1848.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
RG9MTD3 MUTATED 3 3 2
RG9MTD3 WILD-TYPE 101 52 79
'RG9MTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 0.85

Table S1849.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
RG9MTD3 MUTATED 1 1 0 1
RG9MTD3 WILD-TYPE 13 46 21 29
'RG9MTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 0.46

Table S1850.  Gene #172: 'RG9MTD3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
RG9MTD3 MUTATED 2 0 1
RG9MTD3 WILD-TYPE 32 53 24
'KANK4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0378 (Fisher's exact test), Q value = 0.23

Table S1851.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
KANK4 MUTATED 0 6 4 0
KANK4 WILD-TYPE 71 81 50 30

Figure S403.  Get High-res Image Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'KANK4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.717 (Fisher's exact test), Q value = 0.99

Table S1852.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
KANK4 MUTATED 2 1 5
KANK4 WILD-TYPE 42 27 58
'KANK4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0681 (Fisher's exact test), Q value = 0.32

Table S1853.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
KANK4 MUTATED 1 0 4 2 1 2 0
KANK4 WILD-TYPE 23 50 27 17 21 31 24
'KANK4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.74

Table S1854.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
KANK4 MUTATED 2 6 2 0
KANK4 WILD-TYPE 66 72 29 26
'KANK4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.53

Table S1855.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
KANK4 MUTATED 3 2 4 2
KANK4 WILD-TYPE 61 71 32 72
'KANK4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 0.45

Table S1856.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
KANK4 MUTATED 0 1 1 3 4 1 1
KANK4 WILD-TYPE 44 40 16 30 31 30 45
'KANK4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 0.89

Table S1857.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
KANK4 MUTATED 1 1 5 2 1
KANK4 WILD-TYPE 40 39 59 73 19
'KANK4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.338 (Fisher's exact test), Q value = 0.68

Table S1858.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
KANK4 MUTATED 7 1 2
KANK4 WILD-TYPE 97 54 79
'KANK4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 0.7

Table S1859.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
KANK4 MUTATED 0 2 1 4
KANK4 WILD-TYPE 14 45 20 26
'KANK4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.413 (Fisher's exact test), Q value = 0.75

Table S1860.  Gene #173: 'KANK4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
KANK4 MUTATED 2 2 3
KANK4 WILD-TYPE 32 51 22
'MYOM1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.47

Table S1861.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
MYOM1 MUTATED 4 1 1 0
MYOM1 WILD-TYPE 9 17 12 7
'MYOM1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0951 (Fisher's exact test), Q value = 0.36

Table S1862.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
MYOM1 MUTATED 1 0 3 1 1
MYOM1 WILD-TYPE 11 10 4 6 14
'MYOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0544 (Fisher's exact test), Q value = 0.28

Table S1863.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MYOM1 MUTATED 3 14 3 3
MYOM1 WILD-TYPE 68 73 51 27
'MYOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.53

Table S1864.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MYOM1 MUTATED 7 1 4
MYOM1 WILD-TYPE 37 27 59
'MYOM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 0.98

Table S1865.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MYOM1 MUTATED 2 5 5 1 1 5 1
MYOM1 WILD-TYPE 22 45 26 18 21 28 23
'MYOM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.484 (Fisher's exact test), Q value = 0.82

Table S1866.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MYOM1 MUTATED 5 10 4 1
MYOM1 WILD-TYPE 63 68 27 25
'MYOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.47

Table S1867.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MYOM1 MUTATED 6 8 6 3
MYOM1 WILD-TYPE 58 65 30 71
'MYOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 0.37

Table S1868.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MYOM1 MUTATED 2 3 2 6 6 3 1
MYOM1 WILD-TYPE 42 38 15 27 29 28 45
'MYOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.52

Table S1869.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MYOM1 MUTATED 4 3 10 3 2
MYOM1 WILD-TYPE 37 37 54 72 18
'MYOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0157 (Fisher's exact test), Q value = 0.14

Table S1870.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MYOM1 MUTATED 15 5 2
MYOM1 WILD-TYPE 89 50 79

Figure S404.  Get High-res Image Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MYOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 0.66

Table S1871.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MYOM1 MUTATED 2 2 3 2
MYOM1 WILD-TYPE 12 45 18 28
'MYOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0344 (Fisher's exact test), Q value = 0.22

Table S1872.  Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MYOM1 MUTATED 4 1 4
MYOM1 WILD-TYPE 30 52 21

Figure S405.  Get High-res Image Gene #174: 'MYOM1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MORC3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.52

Table S1873.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
MORC3 MUTATED 2 7 1 0
MORC3 WILD-TYPE 69 80 53 30
'MORC3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 0.75

Table S1874.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
MORC3 MUTATED 3 0 3
MORC3 WILD-TYPE 41 28 60
'MORC3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0641 (Fisher's exact test), Q value = 0.31

Table S1875.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
MORC3 MUTATED 0 0 4 1 2 1 1
MORC3 WILD-TYPE 24 50 27 18 20 32 23
'MORC3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0565 (Fisher's exact test), Q value = 0.28

Table S1876.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
MORC3 MUTATED 0 5 3 1
MORC3 WILD-TYPE 68 73 28 25
'MORC3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0019

Table S1877.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
MORC3 MUTATED 0 3 7 0
MORC3 WILD-TYPE 64 70 29 74

Figure S406.  Get High-res Image Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MORC3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00024 (Fisher's exact test), Q value = 0.0083

Table S1878.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
MORC3 MUTATED 0 0 3 3 4 0 0
MORC3 WILD-TYPE 44 41 14 30 31 31 46

Figure S407.  Get High-res Image Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MORC3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0508 (Fisher's exact test), Q value = 0.27

Table S1879.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
MORC3 MUTATED 3 1 5 0 0
MORC3 WILD-TYPE 38 39 59 75 20
'MORC3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0365 (Fisher's exact test), Q value = 0.23

Table S1880.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
MORC3 MUTATED 5 4 0
MORC3 WILD-TYPE 99 51 81

Figure S408.  Get High-res Image Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MORC3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0169 (Fisher's exact test), Q value = 0.14

Table S1881.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
MORC3 MUTATED 0 0 0 4
MORC3 WILD-TYPE 14 47 21 26

Figure S409.  Get High-res Image Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'MORC3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0656 (Fisher's exact test), Q value = 0.31

Table S1882.  Gene #175: 'MORC3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
MORC3 MUTATED 3 0 1
MORC3 WILD-TYPE 31 53 24
'CCDC82 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 0.83

Table S1883.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CCDC82 MUTATED 2 1 0 0
CCDC82 WILD-TYPE 11 17 13 7
'CCDC82 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 0.63

Table S1884.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CCDC82 MUTATED 1 0 1 1 0
CCDC82 WILD-TYPE 11 10 6 6 15
'CCDC82 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.47

Table S1885.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CCDC82 MUTATED 1 8 2 1
CCDC82 WILD-TYPE 70 79 52 29
'CCDC82 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1886.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CCDC82 MUTATED 3 1 4
CCDC82 WILD-TYPE 41 27 59
'CCDC82 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 0.96

Table S1887.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CCDC82 MUTATED 1 1 3 2 1 2 2
CCDC82 WILD-TYPE 23 49 28 17 21 31 22
'CCDC82 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 0.51

Table S1888.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CCDC82 MUTATED 1 7 2 2
CCDC82 WILD-TYPE 67 71 29 24
'CCDC82 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0542 (Fisher's exact test), Q value = 0.28

Table S1889.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CCDC82 MUTATED 3 3 5 1
CCDC82 WILD-TYPE 61 70 31 73
'CCDC82 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00314 (Fisher's exact test), Q value = 0.046

Table S1890.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CCDC82 MUTATED 1 0 1 6 3 1 0
CCDC82 WILD-TYPE 43 41 16 27 32 30 46

Figure S410.  Get High-res Image Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC82 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0418 (Fisher's exact test), Q value = 0.24

Table S1891.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CCDC82 MUTATED 2 0 7 1 1
CCDC82 WILD-TYPE 39 40 57 74 19

Figure S411.  Get High-res Image Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CCDC82 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 0.51

Table S1892.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CCDC82 MUTATED 7 3 1
CCDC82 WILD-TYPE 97 52 80
'CCDC82 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 0.75

Table S1893.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CCDC82 MUTATED 1 1 1 3
CCDC82 WILD-TYPE 13 46 20 27
'CCDC82 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0198 (Fisher's exact test), Q value = 0.15

Table S1894.  Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CCDC82 MUTATED 4 0 2
CCDC82 WILD-TYPE 30 53 23

Figure S412.  Get High-res Image Gene #176: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'B3GALT5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.42

Table S1895.  Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
B3GALT5 MUTATED 0 4 0 0
B3GALT5 WILD-TYPE 71 83 54 30
'B3GALT5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 0.69

Table S1896.  Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
B3GALT5 MUTATED 1 0 2 0 0 1 0
B3GALT5 WILD-TYPE 23 50 29 19 22 32 24
'B3GALT5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 0.41

Table S1897.  Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
B3GALT5 MUTATED 2 0 2 0
B3GALT5 WILD-TYPE 66 78 29 26
'B3GALT5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.681 (Fisher's exact test), Q value = 0.96

Table S1898.  Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
B3GALT5 MUTATED 0 2 0 2
B3GALT5 WILD-TYPE 64 71 36 72
'B3GALT5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.422 (Fisher's exact test), Q value = 0.76

Table S1899.  Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
B3GALT5 MUTATED 0 0 0 1 2 0 1
B3GALT5 WILD-TYPE 44 41 17 32 33 31 45
'B3GALT5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S1900.  Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
B3GALT5 MUTATED 0 1 1 2 0
B3GALT5 WILD-TYPE 41 39 63 73 20
'B3GALT5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S1901.  Gene #177: 'B3GALT5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
B3GALT5 MUTATED 1 1 2
B3GALT5 WILD-TYPE 103 54 79
'NOC3L MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S1902.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
NOC3L MUTATED 1 2 0 0
NOC3L WILD-TYPE 12 16 13 7
'NOC3L MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.53

Table S1903.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
NOC3L MUTATED 2 0 1 0 0
NOC3L WILD-TYPE 10 10 6 7 15
'NOC3L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0192 (Fisher's exact test), Q value = 0.15

Table S1904.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NOC3L MUTATED 0 8 3 0
NOC3L WILD-TYPE 71 79 51 30

Figure S413.  Get High-res Image Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'NOC3L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 0.96

Table S1905.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
NOC3L MUTATED 1 0 3
NOC3L WILD-TYPE 43 28 60
'NOC3L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.276 (Fisher's exact test), Q value = 0.63

Table S1906.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NOC3L MUTATED 2 2 3 2 1 0 0
NOC3L WILD-TYPE 22 48 28 17 21 33 24
'NOC3L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 0.99

Table S1907.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NOC3L MUTATED 4 5 1 0
NOC3L WILD-TYPE 64 73 30 26
'NOC3L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.669 (Fisher's exact test), Q value = 0.96

Table S1908.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NOC3L MUTATED 2 3 3 3
NOC3L WILD-TYPE 62 70 33 71
'NOC3L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00281 (Fisher's exact test), Q value = 0.043

Table S1909.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NOC3L MUTATED 0 0 0 5 4 0 2
NOC3L WILD-TYPE 44 41 17 28 31 31 44

Figure S414.  Get High-res Image Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NOC3L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.387 (Fisher's exact test), Q value = 0.73

Table S1910.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NOC3L MUTATED 1 0 5 3 1
NOC3L WILD-TYPE 40 40 59 72 19
'NOC3L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 0.41

Table S1911.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NOC3L MUTATED 7 0 3
NOC3L WILD-TYPE 97 55 78
'NOC3L MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S1912.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
NOC3L MUTATED 0 1 1 1
NOC3L WILD-TYPE 14 46 20 29
'NOC3L MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.081 (Fisher's exact test), Q value = 0.34

Table S1913.  Gene #178: 'NOC3L MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
NOC3L MUTATED 1 0 2
NOC3L WILD-TYPE 33 53 23
'NSUN4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.48

Table S1914.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
NSUN4 MUTATED 0 3 0 0
NSUN4 WILD-TYPE 13 15 13 7
'NSUN4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0545 (Fisher's exact test), Q value = 0.28

Table S1915.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
NSUN4 MUTATED 3 0 0 0 0
NSUN4 WILD-TYPE 9 10 7 7 15
'NSUN4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.704 (Fisher's exact test), Q value = 0.98

Table S1916.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NSUN4 MUTATED 1 3 2 0
NSUN4 WILD-TYPE 70 84 52 30
'NSUN4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1917.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
NSUN4 MUTATED 1 0 2
NSUN4 WILD-TYPE 43 28 61
'NSUN4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.718 (Fisher's exact test), Q value = 0.99

Table S1918.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NSUN4 MUTATED 1 1 1 1 1 0 0
NSUN4 WILD-TYPE 23 49 30 18 21 33 24
'NSUN4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1919.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NSUN4 MUTATED 2 2 1 0
NSUN4 WILD-TYPE 66 76 30 26
'NSUN4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S1920.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NSUN4 MUTATED 2 2 1 1
NSUN4 WILD-TYPE 62 71 35 73
'NSUN4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0814 (Fisher's exact test), Q value = 0.34

Table S1921.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NSUN4 MUTATED 1 0 0 2 3 0 0
NSUN4 WILD-TYPE 43 41 17 31 32 31 46
'NSUN4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 0.87

Table S1922.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NSUN4 MUTATED 2 0 2 1 0
NSUN4 WILD-TYPE 39 40 62 74 20
'NSUN4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S1923.  Gene #179: 'NSUN4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NSUN4 MUTATED 3 1 1
NSUN4 WILD-TYPE 101 54 80
'ASXL2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 0.83

Table S1924.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ASXL2 MUTATED 2 1 0 0
ASXL2 WILD-TYPE 11 17 13 7
'ASXL2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.284 (Fisher's exact test), Q value = 0.63

Table S1925.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ASXL2 MUTATED 1 0 1 1 0
ASXL2 WILD-TYPE 11 10 6 6 15
'ASXL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.151 (Fisher's exact test), Q value = 0.47

Table S1926.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ASXL2 MUTATED 1 8 4 1
ASXL2 WILD-TYPE 70 79 50 29
'ASXL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.717 (Fisher's exact test), Q value = 0.99

Table S1927.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ASXL2 MUTATED 2 1 5
ASXL2 WILD-TYPE 42 27 58
'ASXL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S1928.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ASXL2 MUTATED 1 2 4 1 1 1 1
ASXL2 WILD-TYPE 23 48 27 18 21 32 23
'ASXL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.663 (Fisher's exact test), Q value = 0.95

Table S1929.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ASXL2 MUTATED 2 6 2 1
ASXL2 WILD-TYPE 66 72 29 25
'ASXL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.46

Table S1930.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ASXL2 MUTATED 3 4 5 2
ASXL2 WILD-TYPE 61 69 31 72
'ASXL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00895 (Fisher's exact test), Q value = 0.092

Table S1931.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ASXL2 MUTATED 1 1 1 6 4 1 0
ASXL2 WILD-TYPE 43 40 16 27 31 30 46

Figure S415.  Get High-res Image Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ASXL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 0.75

Table S1932.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ASXL2 MUTATED 3 1 5 2 2
ASXL2 WILD-TYPE 38 39 59 73 18
'ASXL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 0.51

Table S1933.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ASXL2 MUTATED 9 2 2
ASXL2 WILD-TYPE 95 53 79
'ASXL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 0.99

Table S1934.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ASXL2 MUTATED 0 2 2 2
ASXL2 WILD-TYPE 14 45 19 28
'ASXL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.263 (Fisher's exact test), Q value = 0.61

Table S1935.  Gene #180: 'ASXL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ASXL2 MUTATED 3 1 2
ASXL2 WILD-TYPE 31 52 23
'CHD4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0491 (Fisher's exact test), Q value = 0.26

Table S1936.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
CHD4 MUTATED 1 6 0 2
CHD4 WILD-TYPE 12 12 13 5

Figure S416.  Get High-res Image Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'CHD4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 0.68

Table S1937.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
CHD4 MUTATED 2 4 0 1 2
CHD4 WILD-TYPE 10 6 7 6 13
'CHD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.65

Table S1938.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
CHD4 MUTATED 8 17 5 5
CHD4 WILD-TYPE 63 70 49 25
'CHD4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S1939.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
CHD4 MUTATED 7 3 9
CHD4 WILD-TYPE 37 25 54
'CHD4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.524 (Fisher's exact test), Q value = 0.84

Table S1940.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
CHD4 MUTATED 2 6 3 2 5 8 3
CHD4 WILD-TYPE 22 44 28 17 17 25 21
'CHD4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 0.93

Table S1941.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
CHD4 MUTATED 7 12 6 4
CHD4 WILD-TYPE 61 66 25 22
'CHD4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S1942.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
CHD4 MUTATED 10 10 6 9
CHD4 WILD-TYPE 54 63 30 65
'CHD4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.33 (Fisher's exact test), Q value = 0.67

Table S1943.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
CHD4 MUTATED 7 4 2 6 8 1 7
CHD4 WILD-TYPE 37 37 15 27 27 30 39
'CHD4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 0.75

Table S1944.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
CHD4 MUTATED 3 5 12 7 3
CHD4 WILD-TYPE 38 35 52 68 17
'CHD4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1945.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
CHD4 MUTATED 13 8 9
CHD4 WILD-TYPE 91 47 72
'CHD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 0.87

Table S1946.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
CHD4 MUTATED 1 8 1 5
CHD4 WILD-TYPE 13 39 20 25
'CHD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.721 (Fisher's exact test), Q value = 0.99

Table S1947.  Gene #181: 'CHD4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
CHD4 MUTATED 6 6 3
CHD4 WILD-TYPE 28 47 22
'FCN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.057 (Fisher's exact test), Q value = 0.29

Table S1948.  Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FCN1 MUTATED 0 6 1 0
FCN1 WILD-TYPE 71 81 53 30
'FCN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S1949.  Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
FCN1 MUTATED 2 0 2
FCN1 WILD-TYPE 42 28 61
'FCN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.957 (Fisher's exact test), Q value = 1

Table S1950.  Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FCN1 MUTATED 0 1 1 0 1 1 1
FCN1 WILD-TYPE 24 49 30 19 21 32 23
'FCN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1951.  Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FCN1 MUTATED 1 2 1 1
FCN1 WILD-TYPE 67 76 30 25
'FCN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.576 (Fisher's exact test), Q value = 0.88

Table S1952.  Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FCN1 MUTATED 2 2 2 1
FCN1 WILD-TYPE 62 71 34 73
'FCN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.397 (Fisher's exact test), Q value = 0.74

Table S1953.  Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FCN1 MUTATED 0 1 1 2 2 0 1
FCN1 WILD-TYPE 44 40 16 31 33 31 45
'FCN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.27 (Fisher's exact test), Q value = 0.62

Table S1954.  Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FCN1 MUTATED 0 1 4 1 1
FCN1 WILD-TYPE 41 39 60 74 19
'FCN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.434 (Fisher's exact test), Q value = 0.77

Table S1955.  Gene #182: 'FCN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FCN1 MUTATED 5 1 1
FCN1 WILD-TYPE 99 54 80
'NIPA2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 0.5

Table S1956.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
NIPA2 MUTATED 0 5 2 1
NIPA2 WILD-TYPE 71 82 52 29
'NIPA2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S1957.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
NIPA2 MUTATED 2 0 2
NIPA2 WILD-TYPE 42 28 61
'NIPA2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 0.83

Table S1958.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
NIPA2 MUTATED 0 2 1 0 0 3 0
NIPA2 WILD-TYPE 24 48 30 19 22 30 24
'NIPA2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 0.46

Table S1959.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
NIPA2 MUTATED 2 1 3 0
NIPA2 WILD-TYPE 66 77 28 26
'NIPA2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0125 (Fisher's exact test), Q value = 0.12

Table S1960.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
NIPA2 MUTATED 0 3 4 1
NIPA2 WILD-TYPE 64 70 32 73

Figure S417.  Get High-res Image Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'NIPA2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.041 (Fisher's exact test), Q value = 0.24

Table S1961.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
NIPA2 MUTATED 0 1 2 1 1 3 0
NIPA2 WILD-TYPE 44 40 15 32 34 28 46

Figure S418.  Get High-res Image Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'NIPA2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.063 (Fisher's exact test), Q value = 0.3

Table S1962.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
NIPA2 MUTATED 0 0 6 2 0
NIPA2 WILD-TYPE 41 40 58 73 20
'NIPA2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 0.89

Table S1963.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
NIPA2 MUTATED 3 3 2
NIPA2 WILD-TYPE 101 52 79
'NIPA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.54

Table S1964.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
NIPA2 MUTATED 0 0 1 2
NIPA2 WILD-TYPE 14 47 20 28
'NIPA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 0.78

Table S1965.  Gene #183: 'NIPA2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
NIPA2 MUTATED 2 1 0
NIPA2 WILD-TYPE 32 52 25
'C14ORF118 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S1966.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
C14ORF118 MUTATED 2 1 1 0
C14ORF118 WILD-TYPE 11 17 12 7
'C14ORF118 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0922 (Fisher's exact test), Q value = 0.36

Table S1967.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
C14ORF118 MUTATED 1 0 2 1 0
C14ORF118 WILD-TYPE 11 10 5 6 15
'C14ORF118 MUTATION STATUS' versus 'CN_CNMF'

P value = 2e-05 (Fisher's exact test), Q value = 0.0015

Table S1968.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
C14ORF118 MUTATED 0 13 0 0
C14ORF118 WILD-TYPE 71 74 54 30

Figure S419.  Get High-res Image Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'C14ORF118 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1969.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
C14ORF118 MUTATED 2 2 3
C14ORF118 WILD-TYPE 42 26 60
'C14ORF118 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.168 (Fisher's exact test), Q value = 0.49

Table S1970.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
C14ORF118 MUTATED 1 0 4 1 2 2 1
C14ORF118 WILD-TYPE 23 50 27 18 20 31 23
'C14ORF118 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.251 (Fisher's exact test), Q value = 0.6

Table S1971.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
C14ORF118 MUTATED 2 4 4 1
C14ORF118 WILD-TYPE 66 74 27 25
'C14ORF118 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 0.76

Table S1972.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
C14ORF118 MUTATED 2 3 4 4
C14ORF118 WILD-TYPE 62 70 32 70
'C14ORF118 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0864 (Fisher's exact test), Q value = 0.35

Table S1973.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
C14ORF118 MUTATED 1 0 1 4 4 2 1
C14ORF118 WILD-TYPE 43 41 16 29 31 29 45
'C14ORF118 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.42

Table S1974.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
C14ORF118 MUTATED 0 1 7 3 1
C14ORF118 WILD-TYPE 41 39 57 72 19
'C14ORF118 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S1975.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
C14ORF118 MUTATED 6 3 3
C14ORF118 WILD-TYPE 98 52 78
'C14ORF118 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 0.91

Table S1976.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
C14ORF118 MUTATED 0 2 1 3
C14ORF118 WILD-TYPE 14 45 20 27
'C14ORF118 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 0.87

Table S1977.  Gene #184: 'C14ORF118 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
C14ORF118 MUTATED 3 2 1
C14ORF118 WILD-TYPE 31 51 24
'THAP5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.51

Table S1978.  Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
THAP5 MUTATED 0 3 3 0
THAP5 WILD-TYPE 71 84 51 30
'THAP5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 0.45

Table S1979.  Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
THAP5 MUTATED 0 0 4
THAP5 WILD-TYPE 44 28 59
'THAP5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 0.4

Table S1980.  Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
THAP5 MUTATED 1 0 1 1 2 0 0
THAP5 WILD-TYPE 23 50 30 18 20 33 24
'THAP5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.735 (Fisher's exact test), Q value = 0.99

Table S1981.  Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
THAP5 MUTATED 1 3 1 0
THAP5 WILD-TYPE 67 75 30 26
'THAP5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 0.82

Table S1982.  Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
THAP5 MUTATED 1 2 2 1
THAP5 WILD-TYPE 63 71 34 73
'THAP5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00543 (Fisher's exact test), Q value = 0.065

Table S1983.  Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
THAP5 MUTATED 0 0 0 2 4 0 0
THAP5 WILD-TYPE 44 41 17 31 31 31 46

Figure S420.  Get High-res Image Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'THAP5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 0.91

Table S1984.  Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
THAP5 MUTATED 1 0 3 1 0
THAP5 WILD-TYPE 40 40 61 74 20
'THAP5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 0.65

Table S1985.  Gene #185: 'THAP5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
THAP5 MUTATED 4 0 1
THAP5 WILD-TYPE 100 55 80
'ZNF611 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1986.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
ZNF611 MUTATED 1 1 1 0
ZNF611 WILD-TYPE 12 17 12 7
'ZNF611 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0787 (Fisher's exact test), Q value = 0.33

Table S1987.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
ZNF611 MUTATED 1 0 2 0 0
ZNF611 WILD-TYPE 11 10 5 7 15
'ZNF611 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0114 (Fisher's exact test), Q value = 0.11

Table S1988.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF611 MUTATED 1 10 1 0
ZNF611 WILD-TYPE 70 77 53 30

Figure S421.  Get High-res Image Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF611 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 0.75

Table S1989.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF611 MUTATED 3 0 5
ZNF611 WILD-TYPE 41 28 58
'ZNF611 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.4

Table S1990.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF611 MUTATED 1 0 3 3 1 2 1
ZNF611 WILD-TYPE 23 50 28 16 21 31 23
'ZNF611 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0999 (Fisher's exact test), Q value = 0.37

Table S1991.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF611 MUTATED 1 5 4 1
ZNF611 WILD-TYPE 67 73 27 25
'ZNF611 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0898 (Fisher's exact test), Q value = 0.36

Table S1992.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF611 MUTATED 3 2 5 2
ZNF611 WILD-TYPE 61 71 31 72
'ZNF611 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00304 (Fisher's exact test), Q value = 0.045

Table S1993.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF611 MUTATED 1 0 1 6 3 1 0
ZNF611 WILD-TYPE 43 41 16 27 32 30 46

Figure S422.  Get High-res Image Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF611 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0384 (Fisher's exact test), Q value = 0.23

Table S1994.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF611 MUTATED 1 1 8 1 1
ZNF611 WILD-TYPE 40 39 56 74 19

Figure S423.  Get High-res Image Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ZNF611 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.46

Table S1995.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF611 MUTATED 8 3 1
ZNF611 WILD-TYPE 96 52 80
'ZNF611 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 0.7

Table S1996.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
ZNF611 MUTATED 0 1 1 3
ZNF611 WILD-TYPE 14 46 20 27
'ZNF611 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0301 (Fisher's exact test), Q value = 0.2

Table S1997.  Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
ZNF611 MUTATED 2 0 3
ZNF611 WILD-TYPE 32 53 22

Figure S424.  Get High-res Image Gene #186: 'ZNF611 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ZCCHC18 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0574 (Fisher's exact test), Q value = 0.29

Table S1998.  Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZCCHC18 MUTATED 0 5 0 1
ZCCHC18 WILD-TYPE 71 82 54 29
'ZCCHC18 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.65

Table S1999.  Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZCCHC18 MUTATED 0 0 3
ZCCHC18 WILD-TYPE 44 28 60
'ZCCHC18 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.135 (Fisher's exact test), Q value = 0.44

Table S2000.  Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZCCHC18 MUTATED 1 0 2 0 2 0 1
ZCCHC18 WILD-TYPE 23 50 29 19 20 33 23
'ZCCHC18 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 0.38

Table S2001.  Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZCCHC18 MUTATED 1 1 3 1
ZCCHC18 WILD-TYPE 67 77 28 25
'ZCCHC18 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0107 (Fisher's exact test), Q value = 0.11

Table S2002.  Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZCCHC18 MUTATED 0 3 3 0
ZCCHC18 WILD-TYPE 64 70 33 74

Figure S425.  Get High-res Image Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ZCCHC18 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00489 (Fisher's exact test), Q value = 0.062

Table S2003.  Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZCCHC18 MUTATED 0 0 0 2 4 0 0
ZCCHC18 WILD-TYPE 44 41 17 31 31 31 46

Figure S426.  Get High-res Image Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZCCHC18 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0778 (Fisher's exact test), Q value = 0.33

Table S2004.  Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZCCHC18 MUTATED 0 1 4 0 0
ZCCHC18 WILD-TYPE 41 39 60 75 20
'ZCCHC18 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 0.53

Table S2005.  Gene #187: 'ZCCHC18 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZCCHC18 MUTATED 4 1 0
ZCCHC18 WILD-TYPE 100 54 81
'PRKCE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0992 (Fisher's exact test), Q value = 0.37

Table S2006.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PRKCE MUTATED 0 6 2 1
PRKCE WILD-TYPE 71 81 52 29
'PRKCE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 0.75

Table S2007.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PRKCE MUTATED 3 0 3
PRKCE WILD-TYPE 41 28 60
'PRKCE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.565 (Fisher's exact test), Q value = 0.87

Table S2008.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PRKCE MUTATED 0 1 2 0 1 3 1
PRKCE WILD-TYPE 24 49 29 19 21 30 23
'PRKCE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.521 (Fisher's exact test), Q value = 0.84

Table S2009.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PRKCE MUTATED 1 4 2 1
PRKCE WILD-TYPE 67 74 29 25
'PRKCE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.45 (Fisher's exact test), Q value = 0.78

Table S2010.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PRKCE MUTATED 2 4 2 1
PRKCE WILD-TYPE 62 69 34 73
'PRKCE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0153 (Fisher's exact test), Q value = 0.13

Table S2011.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PRKCE MUTATED 0 0 1 3 4 0 1
PRKCE WILD-TYPE 44 41 16 30 31 31 45

Figure S427.  Get High-res Image Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PRKCE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.287 (Fisher's exact test), Q value = 0.63

Table S2012.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PRKCE MUTATED 1 0 5 2 1
PRKCE WILD-TYPE 40 40 59 73 19
'PRKCE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.499 (Fisher's exact test), Q value = 0.83

Table S2013.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PRKCE MUTATED 6 1 2
PRKCE WILD-TYPE 98 54 79
'PRKCE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S2014.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PRKCE MUTATED 0 1 1 1
PRKCE WILD-TYPE 14 46 20 29
'PRKCE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S2015.  Gene #188: 'PRKCE MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PRKCE MUTATED 1 1 1
PRKCE WILD-TYPE 33 52 24
'BMP2K MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.52

Table S2016.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
BMP2K MUTATED 3 1 0 0
BMP2K WILD-TYPE 10 17 13 7
'BMP2K MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0913 (Fisher's exact test), Q value = 0.36

Table S2017.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
BMP2K MUTATED 1 0 1 2 0
BMP2K WILD-TYPE 11 10 6 5 15
'BMP2K MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00516 (Fisher's exact test), Q value = 0.064

Table S2018.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
BMP2K MUTATED 0 9 1 3
BMP2K WILD-TYPE 71 78 53 27

Figure S428.  Get High-res Image Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'BMP2K MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.533 (Fisher's exact test), Q value = 0.85

Table S2019.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
BMP2K MUTATED 1 1 5
BMP2K WILD-TYPE 43 27 58
'BMP2K MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 0.98

Table S2020.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
BMP2K MUTATED 1 2 2 1 0 4 1
BMP2K WILD-TYPE 23 48 29 18 22 29 23
'BMP2K MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S2021.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
BMP2K MUTATED 5 4 1 1
BMP2K WILD-TYPE 63 74 30 25
'BMP2K MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0306 (Fisher's exact test), Q value = 0.21

Table S2022.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
BMP2K MUTATED 0 6 4 3
BMP2K WILD-TYPE 64 67 32 71

Figure S429.  Get High-res Image Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'BMP2K MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0158 (Fisher's exact test), Q value = 0.14

Table S2023.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
BMP2K MUTATED 0 1 1 6 3 1 1
BMP2K WILD-TYPE 44 40 16 27 32 30 45

Figure S430.  Get High-res Image Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'BMP2K MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 0.99

Table S2024.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
BMP2K MUTATED 1 2 5 5 0
BMP2K WILD-TYPE 40 38 59 70 20
'BMP2K MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.464 (Fisher's exact test), Q value = 0.8

Table S2025.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
BMP2K MUTATED 7 1 5
BMP2K WILD-TYPE 97 54 76
'BMP2K MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S2026.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
BMP2K MUTATED 1 3 1 1
BMP2K WILD-TYPE 13 44 20 29
'BMP2K MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2027.  Gene #189: 'BMP2K MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
BMP2K MUTATED 2 3 1
BMP2K WILD-TYPE 32 50 24
'PRPF38B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00666 (Fisher's exact test), Q value = 0.075

Table S2028.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
PRPF38B MUTATED 0 9 2 0
PRPF38B WILD-TYPE 71 78 52 30

Figure S431.  Get High-res Image Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PRPF38B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.64

Table S2029.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
PRPF38B MUTATED 1 0 5
PRPF38B WILD-TYPE 43 28 58
'PRPF38B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S2030.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
PRPF38B MUTATED 1 2 3 2 1 1 1
PRPF38B WILD-TYPE 23 48 28 17 21 32 23
'PRPF38B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2031.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
PRPF38B MUTATED 4 4 2 1
PRPF38B WILD-TYPE 64 74 29 25
'PRPF38B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S2032.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
PRPF38B MUTATED 2 6 2 1
PRPF38B WILD-TYPE 62 67 34 73
'PRPF38B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00043 (Fisher's exact test), Q value = 0.013

Table S2033.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
PRPF38B MUTATED 0 1 0 5 5 0 0
PRPF38B WILD-TYPE 44 40 17 28 30 31 46

Figure S432.  Get High-res Image Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PRPF38B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.711 (Fisher's exact test), Q value = 0.98

Table S2034.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
PRPF38B MUTATED 1 1 5 3 1
PRPF38B WILD-TYPE 40 39 59 72 19
'PRPF38B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0234 (Fisher's exact test), Q value = 0.17

Table S2035.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
PRPF38B MUTATED 9 0 2
PRPF38B WILD-TYPE 95 55 79

Figure S433.  Get High-res Image Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PRPF38B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S2036.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
PRPF38B MUTATED 0 1 1 1
PRPF38B WILD-TYPE 14 46 20 29
'PRPF38B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 0.46

Table S2037.  Gene #190: 'PRPF38B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
PRPF38B MUTATED 2 0 1
PRPF38B WILD-TYPE 32 53 24
'LGMN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 0.83

Table S2038.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
LGMN MUTATED 2 1 0 0
LGMN WILD-TYPE 11 17 13 7
'LGMN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0765 (Fisher's exact test), Q value = 0.33

Table S2039.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
LGMN MUTATED 1 0 2 0 0
LGMN WILD-TYPE 11 10 5 7 15
'LGMN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.6

Table S2040.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
LGMN MUTATED 0 4 2 1
LGMN WILD-TYPE 71 83 52 29
'LGMN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 0.66

Table S2041.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
LGMN MUTATED 2 0 2 0 1 1 1
LGMN WILD-TYPE 22 50 29 19 21 32 23
'LGMN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2042.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
LGMN MUTATED 2 3 1 1
LGMN WILD-TYPE 66 75 30 25
'LGMN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 3e-04 (Fisher's exact test), Q value = 0.01

Table S2043.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
LGMN MUTATED 0 2 5 0
LGMN WILD-TYPE 64 71 31 74

Figure S434.  Get High-res Image Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'LGMN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00103 (Fisher's exact test), Q value = 0.024

Table S2044.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
LGMN MUTATED 0 0 1 0 5 1 0
LGMN WILD-TYPE 44 41 16 33 30 30 46

Figure S435.  Get High-res Image Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'LGMN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.177 (Fisher's exact test), Q value = 0.51

Table S2045.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
LGMN MUTATED 1 1 4 0 0
LGMN WILD-TYPE 40 39 60 75 20
'LGMN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 0.44

Table S2046.  Gene #191: 'LGMN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
LGMN MUTATED 4 2 0
LGMN WILD-TYPE 100 53 81
'SSH2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S2047.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
SSH2 MUTATED 2 1 1 0
SSH2 WILD-TYPE 11 17 12 7
'SSH2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0937 (Fisher's exact test), Q value = 0.36

Table S2048.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
SSH2 MUTATED 1 0 2 1 0
SSH2 WILD-TYPE 11 10 5 6 15
'SSH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00056 (Fisher's exact test), Q value = 0.016

Table S2049.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
SSH2 MUTATED 0 11 1 0
SSH2 WILD-TYPE 71 76 53 30

Figure S436.  Get High-res Image Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'SSH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.545 (Fisher's exact test), Q value = 0.86

Table S2050.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
SSH2 MUTATED 2 1 1
SSH2 WILD-TYPE 42 27 62
'SSH2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S2051.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
SSH2 MUTATED 1 3 2 1 1 3 0
SSH2 WILD-TYPE 23 47 29 18 21 30 24
'SSH2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.318 (Fisher's exact test), Q value = 0.66

Table S2052.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
SSH2 MUTATED 5 3 3 0
SSH2 WILD-TYPE 63 75 28 26
'SSH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0177 (Fisher's exact test), Q value = 0.14

Table S2053.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
SSH2 MUTATED 0 3 5 4
SSH2 WILD-TYPE 64 70 31 70

Figure S437.  Get High-res Image Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SSH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.346 (Fisher's exact test), Q value = 0.69

Table S2054.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
SSH2 MUTATED 0 2 2 3 2 1 2
SSH2 WILD-TYPE 44 39 15 30 33 30 44
'SSH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 0.53

Table S2055.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
SSH2 MUTATED 0 1 6 4 0
SSH2 WILD-TYPE 41 39 58 71 20
'SSH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S2056.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
SSH2 MUTATED 5 3 3
SSH2 WILD-TYPE 99 52 78
'SSH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S2057.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
SSH2 MUTATED 0 2 0 2
SSH2 WILD-TYPE 14 45 21 28
'SSH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 0.52

Table S2058.  Gene #192: 'SSH2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
SSH2 MUTATED 3 1 0
SSH2 WILD-TYPE 31 52 25
'EMR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0072 (Fisher's exact test), Q value = 0.078

Table S2059.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
EMR1 MUTATED 0 9 2 0
EMR1 WILD-TYPE 71 78 52 30

Figure S438.  Get High-res Image Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'EMR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 0.82

Table S2060.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
EMR1 MUTATED 2 0 4
EMR1 WILD-TYPE 42 28 59
'EMR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 0.75

Table S2061.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
EMR1 MUTATED 1 1 4 2 1 1 1
EMR1 WILD-TYPE 23 49 27 17 21 32 23
'EMR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 0.85

Table S2062.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
EMR1 MUTATED 2 5 3 1
EMR1 WILD-TYPE 66 73 28 25
'EMR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 0.46

Table S2063.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
EMR1 MUTATED 1 4 4 2
EMR1 WILD-TYPE 63 69 32 72
'EMR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00097 (Fisher's exact test), Q value = 0.023

Table S2064.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
EMR1 MUTATED 0 0 1 6 3 0 1
EMR1 WILD-TYPE 44 41 16 27 32 31 45

Figure S439.  Get High-res Image Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'EMR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0783 (Fisher's exact test), Q value = 0.33

Table S2065.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
EMR1 MUTATED 0 1 7 2 1
EMR1 WILD-TYPE 41 39 57 73 19
'EMR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S2066.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
EMR1 MUTATED 6 2 3
EMR1 WILD-TYPE 98 53 78
'EMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 0.95

Table S2067.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
EMR1 MUTATED 0 1 1 2
EMR1 WILD-TYPE 14 46 20 28
'EMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0924 (Fisher's exact test), Q value = 0.36

Table S2068.  Gene #193: 'EMR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
EMR1 MUTATED 2 0 2
EMR1 WILD-TYPE 32 53 23
'OR5AK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 0.73

Table S2069.  Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
OR5AK2 MUTATED 0 2 2 1
OR5AK2 WILD-TYPE 71 85 52 29
'OR5AK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 0.75

Table S2070.  Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
OR5AK2 MUTATED 0 1 2 1 0 0 0
OR5AK2 WILD-TYPE 24 49 29 18 22 33 24
'OR5AK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 0.66

Table S2071.  Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
OR5AK2 MUTATED 0 3 1 0
OR5AK2 WILD-TYPE 68 75 30 26
'OR5AK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 0.66

Table S2072.  Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
OR5AK2 MUTATED 1 3 1 0
OR5AK2 WILD-TYPE 63 70 35 74
'OR5AK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0199 (Fisher's exact test), Q value = 0.15

Table S2073.  Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
OR5AK2 MUTATED 0 0 0 2 3 0 0
OR5AK2 WILD-TYPE 44 41 17 31 32 31 46

Figure S440.  Get High-res Image Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'OR5AK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0877 (Fisher's exact test), Q value = 0.36

Table S2074.  Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
OR5AK2 MUTATED 1 0 4 0 0
OR5AK2 WILD-TYPE 40 40 60 75 20
'OR5AK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.202 (Fisher's exact test), Q value = 0.53

Table S2075.  Gene #194: 'OR5AK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
OR5AK2 MUTATED 4 1 0
OR5AK2 WILD-TYPE 100 54 81
'C1ORF101 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S2076.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 13 18 13 7
C1ORF101 MUTATED 1 1 2 0
C1ORF101 WILD-TYPE 12 17 11 7
'C1ORF101 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.323 (Fisher's exact test), Q value = 0.66

Table S2077.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 12 10 7 7 15
C1ORF101 MUTATED 1 0 2 0 1
C1ORF101 WILD-TYPE 11 10 5 7 14
'C1ORF101 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00857 (Fisher's exact test), Q value = 0.089

Table S2078.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
C1ORF101 MUTATED 0 9 3 0
C1ORF101 WILD-TYPE 71 78 51 30

Figure S441.  Get High-res Image Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'C1ORF101 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 0.86

Table S2079.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
C1ORF101 MUTATED 2 1 1
C1ORF101 WILD-TYPE 42 27 62
'C1ORF101 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.632 (Fisher's exact test), Q value = 0.93

Table S2080.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
C1ORF101 MUTATED 1 1 1 2 2 1 1
C1ORF101 WILD-TYPE 23 49 30 17 20 32 23
'C1ORF101 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2081.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
C1ORF101 MUTATED 3 4 1 1
C1ORF101 WILD-TYPE 65 74 30 25
'C1ORF101 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S2082.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
C1ORF101 MUTATED 3 3 3 3
C1ORF101 WILD-TYPE 61 70 33 71
'C1ORF101 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.707 (Fisher's exact test), Q value = 0.98

Table S2083.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
C1ORF101 MUTATED 1 1 1 3 3 1 2
C1ORF101 WILD-TYPE 43 40 16 30 32 30 44
'C1ORF101 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0778 (Fisher's exact test), Q value = 0.33

Table S2084.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
C1ORF101 MUTATED 0 1 7 2 1
C1ORF101 WILD-TYPE 41 39 57 73 19
'C1ORF101 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 0.76

Table S2085.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
C1ORF101 MUTATED 7 2 2
C1ORF101 WILD-TYPE 97 53 79
'C1ORF101 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 0.54

Table S2086.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 14 47 21 30
C1ORF101 MUTATED 0 0 1 2
C1ORF101 WILD-TYPE 14 47 20 28
'C1ORF101 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 0.46

Table S2087.  Gene #195: 'C1ORF101 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 34 53 25
C1ORF101 MUTATED 2 0 1
C1ORF101 WILD-TYPE 32 53 24
'ZNF534 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0373 (Fisher's exact test), Q value = 0.23

Table S2088.  Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
ZNF534 MUTATED 0 7 2 0
ZNF534 WILD-TYPE 71 80 52 30

Figure S442.  Get High-res Image Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZNF534 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 0.45

Table S2089.  Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 44 28 63
ZNF534 MUTATED 0 0 4
ZNF534 WILD-TYPE 44 28 59
'ZNF534 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 0.84

Table S2090.  Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
ZNF534 MUTATED 1 0 2 1 1 1 1
ZNF534 WILD-TYPE 23 50 29 18 21 32 23
'ZNF534 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S2091.  Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
ZNF534 MUTATED 2 3 1 1
ZNF534 WILD-TYPE 66 75 30 25
'ZNF534 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 0.66

Table S2092.  Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
ZNF534 MUTATED 1 3 3 2
ZNF534 WILD-TYPE 63 70 33 72
'ZNF534 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00015 (Fisher's exact test), Q value = 0.0061

Table S2093.  Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
ZNF534 MUTATED 0 0 0 4 5 0 0
ZNF534 WILD-TYPE 44 41 17 29 30 31 46

Figure S443.  Get High-res Image Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ZNF534 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 0.81

Table S2094.  Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
ZNF534 MUTATED 1 0 4 2 1
ZNF534 WILD-TYPE 40 40 60 73 19
'ZNF534 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S2095.  Gene #196: 'ZNF534 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
ZNF534 MUTATED 4 1 3
ZNF534 WILD-TYPE 100 54 78
'FAM122A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0158 (Fisher's exact test), Q value = 0.14

Table S2096.  Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 71 87 54 30
FAM122A MUTATED 0 6 0 0
FAM122A WILD-TYPE 71 81 54 30

Figure S444.  Get High-res Image Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'FAM122A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 0.52

Table S2097.  Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 24 50 31 19 22 33 24
FAM122A MUTATED 1 0 2 0 2 1 0
FAM122A WILD-TYPE 23 50 29 19 20 32 24
'FAM122A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 0.5

Table S2098.  Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 68 78 31 26
FAM122A MUTATED 1 2 3 0
FAM122A WILD-TYPE 67 76 28 26
'FAM122A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0103 (Fisher's exact test), Q value = 0.1

Table S2099.  Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 64 73 36 74
FAM122A MUTATED 0 3 3 0
FAM122A WILD-TYPE 64 70 33 74

Figure S445.  Get High-res Image Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'FAM122A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00515 (Fisher's exact test), Q value = 0.064

Table S2100.  Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7
ALL 44 41 17 33 35 31 46
FAM122A MUTATED 0 0 1 0 4 1 0
FAM122A WILD-TYPE 44 41 16 33 31 30 46

Figure S446.  Get High-res Image Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'FAM122A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0775 (Fisher's exact test), Q value = 0.33

Table S2101.  Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 41 40 64 75 20
FAM122A MUTATED 0 1 4 0 0
FAM122A WILD-TYPE 41 39 60 75 20
'FAM122A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.243 (Fisher's exact test), Q value = 0.59

Table S2102.  Gene #197: 'FAM122A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 104 55 81
FAM122A MUTATED 3 2 0
FAM122A WILD-TYPE 101 53 81
Methods & Data
Input

  • Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline

  • Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/UCEC-TP/22815333/transformed.cor.cli.txt

  • Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/UCEC-TP/22553827/UCEC-TP.transferedmergedcluster.txt

  • Number of patients = 248

  • Number of significantly mutated genes = 197

  • Number of Molecular subtypes = 12

  • Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References
[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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