Clustering of miRseq precursor expression: consensus NMF
Pheochromocytoma and Paraganglioma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by Hailei Zhang (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): Clustering of miRseq precursor expression: consensus NMF. Broad Institute of MIT and Harvard. doi:10.7908/C1F47NKM
- Overview
+ Introduction
- Summary

The most robust consensus NMF clustering of 179 samples using the 150 most variable miRs was identified for k = 3 clusters. We computed the clustering for k = 2 to k = 10 and uused the cophenetic correlation coefficient and the average silhouette width calculation to determine the robust clusters.

- Results
+ miR expression patterns of molecular subtypes
+ Silhouette widths, Cophenetic Correlation Coefficients and Consensus matrix
+ Samples assignment with silhouette width
+ Marker miRs of each subtype
+ Methods & Data