Clustering of copy number data by peak region with threshold value: consensus NMF
Uveal Melanoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by Hailei Zhang (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): Clustering of copy number data by peak region with threshold value: consensus NMF. Broad Institute of MIT and Harvard. doi:10.7908/C1ZP45NR
- Overview
+ Introduction
- Summary

The most robust consensus NMF clustering of 80 samples using the 21 copy number focal regions was identified for k = 8 clusters. We computed the clustering for k = 2 to k = 8 and used the cophenetic correlation coefficient to determine the best solution.

- Results
+ Copy number focal events of molecular subtypes
+ Silhouette widths, Cophenetic Correlation Coefficients and Consensus matrix
+ Samples assignment with silhouette width
+ Marker focal events of each subtype
+ Methods & Data