PARADIGM pathway analysis of mRNASeq expression data
Breast Invasive Carcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1SB4541
- Overview
+ Introduction
- Summary

There were 54 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Class IB PI3K non-lipid kinase events 309
Signaling events mediated by Stem cell factor receptor (c-Kit) 289
Reelin signaling pathway 250
EGFR-dependent Endothelin signaling events 249
HIF-1-alpha transcription factor network 210
FOXA2 and FOXA3 transcription factor networks 172
p75(NTR)-mediated signaling 171
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 162
Glucocorticoid receptor regulatory network 160
Angiopoietin receptor Tie2-mediated signaling 157
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data