PARADIGM pathway analysis of mRNA expression data
Breast Invasive Carcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNA expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1HT2NPK
- Overview
+ Introduction
- Summary

There were 51 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Signaling events mediated by Stem cell factor receptor (c-Kit) 246
Signaling mediated by p38-alpha and p38-beta 244
EGFR-dependent Endothelin signaling events 180
Endothelins 165
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 155
Class IB PI3K non-lipid kinase events 137
IGF1 pathway 135
Arf6 signaling events 133
S1P1 pathway 104
FOXM1 transcription factor network 103
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data