PARADIGM pathway analysis of mRNA expression and copy number data
Breast Invasive Carcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNA expression and copy number data. Broad Institute of MIT and Harvard. doi:10.7908/C1D21WZ5
- Overview
+ Introduction
- Summary

There were 54 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Signaling mediated by p38-alpha and p38-beta 247
Signaling events mediated by Stem cell factor receptor (c-Kit) 217
Endothelins 150
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 147
EGFR-dependent Endothelin signaling events 147
Class IB PI3K non-lipid kinase events 126
IGF1 pathway 121
FOXM1 transcription factor network 109
Arf6 signaling events 106
Nongenotropic Androgen signaling 93
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data