PARADIGM pathway analysis of mRNASeq expression data
Pan-kidney cohort (KICH+KIRC+KIRP) (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1WM1CSK
- Overview
+ Introduction
- Summary

There were 46 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Nephrin/Neph1 signaling in the kidney podocyte 423
HIF-1-alpha transcription factor network 224
TCGA08_p53 223
FOXA2 and FOXA3 transcription factor networks 208
PDGFR-alpha signaling pathway 206
FOXM1 transcription factor network 186
Aurora B signaling 179
TCR signaling in naïve CD8+ T cells 177
Syndecan-4-mediated signaling events 170
Glypican 2 network 167
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data