PARADIGM pathway analysis of mRNASeq expression data
Kidney Renal Papillary Cell Carcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1D50MBF
- Overview
+ Introduction
- Summary

There were 35 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Nephrin/Neph1 signaling in the kidney podocyte 134
EGFR-dependent Endothelin signaling events 113
Angiopoietin receptor Tie2-mediated signaling 97
Glypican 2 network 79
FOXA2 and FOXA3 transcription factor networks 69
PDGFR-alpha signaling pathway 66
Thromboxane A2 receptor signaling 51
Glypican 1 network 40
Arf6 signaling events 39
Signaling mediated by p38-alpha and p38-beta 39
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data