PARADIGM pathway analysis of mRNA expression data
Lung Adenocarcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNA expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1Z60NGZ
- Overview
+ Introduction
- Summary

There were 41 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
FOXM1 transcription factor network 8
HIF-1-alpha transcription factor network 7
TCGA08_retinoblastoma 7
IL23-mediated signaling events 5
Osteopontin-mediated events 4
IL4-mediated signaling events 4
Fc-epsilon receptor I signaling in mast cells 4
Endothelins 4
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 4
EGFR-dependent Endothelin signaling events 4
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data