PARADIGM pathway analysis of mRNA expression and copy number data
Lung Squamous Cell Carcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNA expression and copy number data. Broad Institute of MIT and Harvard. doi:10.7908/C1GX4B0C
- Overview
+ Introduction
- Summary

There were 45 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
HIF-1-alpha transcription factor network 26
TCGA08_retinoblastoma 26
IL23-mediated signaling events 22
IL4-mediated signaling events 21
Signaling mediated by p38-alpha and p38-beta 21
Fc-epsilon receptor I signaling in mast cells 19
Glucocorticoid receptor regulatory network 19
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 19
Osteopontin-mediated events 18
Wnt signaling 18
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data