Association of mutation, copy number alteration, and subtype markers with pathways
Ovarian Serous Cystadenocarcinoma (Primary solid tumor)
28 January 2016
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analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2016):
Association of mutation, copy number alteration, and subtype markers with pathways.
Broad Institute of MIT and Harvard.
doi:10.7908/C1KD1XCZ
Overview
Introduction
Summary
There are 14 genes with significant mutation (Q value <= 0.1) and 229 genes with significant copy number alteration (Q value <= 0.25). The identified marker genes (Q value <= 0.01 or within top 2000) are 1220 for subtype 1, 1220 for subtype 2, 1220 for subtype 3. Pathways significantly enriched with these genes (Q value <= 0.01) are identified :
18 pathways significantly enriched with genes with copy number alteration or mutation.
0 pathways significantly enriched with marker genes of gene expression subtype 1
0 pathways significantly enriched with marker genes of gene expression subtype 2
0 pathways significantly enriched with marker genes of gene expression subtype 3
Results
The top five pathways enriched with genes with copy number alteration or mutation
The top five pathways enriched with marker genes of gene expression subtype 1
The top five pathways enriched with marker genes of gene expression subtype 2
The top five pathways enriched with marker genes of gene expression subtype 3
Methods & Data
Copyright © 2016
Broad Institute TCGA GDAC as part of the TCGA Research Network.
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