PARADIGM pathway analysis of mRNASeq expression data
Pancreatic Adenocarcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C17S7N7T
- Overview
+ Introduction
- Summary

There were 48 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
FOXA2 and FOXA3 transcription factor networks 37
IL23-mediated signaling events 36
HIF-1-alpha transcription factor network 33
Nephrin/Neph1 signaling in the kidney podocyte 32
TCGA08_retinoblastoma 29
Signaling events mediated by the Hedgehog family 27
amb2 Integrin signaling 25
IL4-mediated signaling events 23
TCR signaling in naïve CD8+ T cells 21
BCR signaling pathway 21
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data