Glioblastoma Multiforme: Correlation between mRNA expression and clinical features
(primary solid tumor cohort)
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
- Overview
+ Introduction
- Summary

Testing the association between 12042 genes and 5 clinical features across 519 samples, statistically thresholded by Q value < 0.05, 4 clinical features related to at least one genes.

  • 21 genes correlated to 'Time to Death'.

    • CLEC5A ,  EFEMP2 ,  NCOA4 ,  ATP5C1 ,  DIRAS3 ,  ...

  • 76 genes correlated to 'AGE'.

    • RANBP17 ,  FBXO17 ,  TUSC3 ,  KIAA0495 ,  NOL3 ,  ...

  • 23 genes correlated to 'GENDER'.

    • DDX3Y ,  RPS4Y1 ,  JARID1D ,  EIF1AY ,  NLGN4Y ,  ...

  • 2 genes correlated to 'RADIATIONS.RADIATION.REGIMENINDICATION'.

    • NPAT ,  HOXD10

  • No genes correlated to 'KARNOFSKY.PERFORMANCE.SCORE'

- Results
- Overview of the results

Complete statistical result table is provided in Supplement Table 1

Table 1.  Get Full Table This table shows the clinical features, statistical methods used, and the number of genes that are significantly associated with each clinical feature at Q value < 0.05.

Clinical feature Statistical test Significant genes Associated with                 Associated with
Time to Death Cox regression test N=21 shorter survival N=11 longer survival N=10
AGE Spearman correlation test N=76 older N=42 younger N=34
GENDER t test N=23 male N=11 female N=12
KARNOFSKY PERFORMANCE SCORE Spearman correlation test   N=0        
RADIATIONS RADIATION REGIMENINDICATION t test N=2 yes N=1 no N=1
+ Methods & Data
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