This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 81 arm-level events and 12 molecular subtypes across 513 patients, 459 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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2p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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2q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3p gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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3q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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4p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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4q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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7p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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9q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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10p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q gain cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q gain cnv correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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16p gain cnv correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p gain cnv correlated to 'CN_CNMF' and 'RPPA_CNMF'.
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17q gain cnv correlated to 'RPPA_CNMF' and 'RPPA_CHIERARCHICAL'.
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18p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'CN_CNMF'.
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22q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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xq gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q loss cnv correlated to 'MRNASEQ_CHIERARCHICAL'.
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2p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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2q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3p loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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3q loss cnv correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p loss cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q loss cnv correlated to 'RPPA_CNMF'.
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8p loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', and 'MRNASEQ_CHIERARCHICAL'.
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9q loss cnv correlated to 'RPPA_CHIERARCHICAL' and 'MRNASEQ_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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13q loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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16q loss cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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17p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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18p loss cnv correlated to 'MRNA_CHIERARCHICAL' and 'CN_CNMF'.
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18q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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19p loss cnv correlated to 'MIRSEQ_MATURE_CNMF'.
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19q loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p loss cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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20q loss cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CNMF'.
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21q loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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22q loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xq loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 81 arm-level events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 459 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 1p loss | 184 (36%) | 329 |
0.029 (0.0694) |
0.00016 (0.000978) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00312 (0.0114) |
0.00106 (0.00468) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
| 7p gain | 120 (23%) | 393 |
1 (1.00) |
1 (1.00) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0097 (0.0293) |
0.0179 (0.0475) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00141 (0.00591) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
| 10p gain | 57 (11%) | 456 |
1 (1.00) |
0.0423 (0.0938) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00748 (0.0235) |
0.00185 (0.00746) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0273 (0.0664) |
0.296 (0.428) |
0.0179 (0.0475) |
1e-05 (8.6e-05) |
| 20q gain | 44 (9%) | 469 |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0007 (0.00335) |
0.00369 (0.0133) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0452 (0.0978) |
1e-05 (8.6e-05) |
9e-05 (0.000607) |
1e-05 (8.6e-05) |
||
| 8p loss | 17 (3%) | 496 |
0.618 (0.774) |
0.0435 (0.0956) |
2e-05 (0.000156) |
0.0002 (0.00116) |
0.0161 (0.0439) |
0.0102 (0.0305) |
1e-05 (8.6e-05) |
4e-05 (0.00029) |
0.297 (0.429) |
0.00146 (0.00609) |
0.00782 (0.0243) |
1e-05 (8.6e-05) |
| 10p loss | 83 (16%) | 430 |
0.271 (0.403) |
0.883 (1.00) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00742 (0.0235) |
0.00031 (0.00168) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00016 (0.000978) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
| 10q loss | 97 (19%) | 416 |
0.27 (0.403) |
0.881 (1.00) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00907 (0.0275) |
9e-05 (0.000607) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
6e-05 (0.000423) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
| 11p loss | 63 (12%) | 450 |
1 (1.00) |
0.0311 (0.0731) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0114 (0.0335) |
0.317 (0.455) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
2e-05 (0.000156) |
4e-05 (0.00029) |
0.00092 (0.00418) |
1e-05 (8.6e-05) |
| 19q loss | 209 (41%) | 304 |
0.184 (0.293) |
0.0133 (0.0379) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0598 (0.123) |
0.00821 (0.0253) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
| 22q loss | 57 (11%) | 456 |
0.816 (0.973) |
0.00658 (0.0215) |
1e-05 (8.6e-05) |
2e-05 (0.000156) |
0.00036 (0.00192) |
0.0389 (0.0878) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.513 (0.663) |
0.0003 (0.00164) |
0.00165 (0.0068) |
2e-05 (0.000156) |
| 1p gain | 13 (3%) | 500 |
7e-05 (0.000483) |
0.00028 (0.00156) |
0.0233 (0.0589) |
0.296 (0.428) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00656 (0.0215) |
1e-05 (8.6e-05) |
0.00291 (0.0108) |
0.0011 (0.00479) |
||
| 5p gain | 11 (2%) | 502 |
0.00132 (0.0056) |
0.0172 (0.046) |
0.128 (0.222) |
0.036 (0.0828) |
0.00012 (0.000772) |
0.00043 (0.00225) |
0.0257 (0.0634) |
0.0268 (0.0653) |
2e-05 (0.000156) |
0.00078 (0.00368) |
||
| 19q gain | 25 (5%) | 488 |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.133 (0.229) |
0.0138 (0.039) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00247 (0.00945) |
1e-05 (8.6e-05) |
0.00013 (0.000815) |
1e-05 (8.6e-05) |
||
| 20p gain | 45 (9%) | 468 |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00484 (0.0166) |
0.0154 (0.0425) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.105 (0.19) |
1e-05 (8.6e-05) |
0.00027 (0.00151) |
1e-05 (8.6e-05) |
||
| xq gain | 42 (8%) | 471 |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0262 (0.0642) |
0.0249 (0.0621) |
0.00013 (0.000815) |
1e-05 (8.6e-05) |
0.0101 (0.0302) |
0.461 (0.609) |
0.0366 (0.0839) |
0.00196 (0.00781) |
||
| 4p loss | 72 (14%) | 441 |
1 (1.00) |
0.781 (0.937) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0118 (0.0344) |
0.932 (1.00) |
0.00012 (0.000772) |
1e-05 (8.6e-05) |
7e-05 (0.000483) |
0.00105 (0.00468) |
0.00056 (0.00278) |
1e-05 (8.6e-05) |
| 4q loss | 94 (18%) | 419 |
1 (1.00) |
0.408 (0.558) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0186 (0.0488) |
0.402 (0.554) |
0.00119 (0.00512) |
1e-05 (8.6e-05) |
0.00047 (0.00242) |
0.00347 (0.0126) |
0.0072 (0.0229) |
2e-05 (0.000156) |
| xq loss | 70 (14%) | 443 |
0.838 (0.994) |
0.266 (0.398) |
0.0076 (0.0237) |
0.00018 (0.00107) |
7e-05 (0.000483) |
0.0167 (0.045) |
0.00021 (0.00121) |
1e-05 (8.6e-05) |
4e-05 (0.00029) |
0.26 (0.391) |
0.00011 (0.000727) |
0.00069 (0.00334) |
| 7q gain | 150 (29%) | 363 |
0.863 (1.00) |
0.781 (0.937) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0798 (0.154) |
0.0779 (0.151) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.00285 (0.0107) |
1e-05 (8.6e-05) |
2e-05 (0.000156) |
1e-05 (8.6e-05) |
| 19p gain | 99 (19%) | 414 |
0.221 (0.342) |
1 (1.00) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.279 (0.414) |
0.00389 (0.014) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0024 (0.00926) |
0.055 (0.114) |
0.0002 (0.00116) |
1e-05 (8.6e-05) |
| 5q loss | 32 (6%) | 481 |
0.449 (0.596) |
0.237 (0.363) |
0.00081 (0.00379) |
4e-05 (0.00029) |
0.0022 (0.00866) |
0.183 (0.292) |
0.0137 (0.0387) |
1e-05 (8.6e-05) |
0.0001 (0.000666) |
0.116 (0.206) |
0.0155 (0.0425) |
3e-05 (0.000226) |
| 13q loss | 115 (22%) | 398 |
0.179 (0.288) |
2e-05 (0.000156) |
1e-05 (8.6e-05) |
0.0433 (0.0955) |
0.0128 (0.0368) |
0.445 (0.593) |
0.0181 (0.0477) |
0.00117 (0.00505) |
0.0514 (0.108) |
0.0206 (0.0531) |
0.455 (0.603) |
0.0447 (0.0974) |
| 14q loss | 81 (16%) | 432 |
0.467 (0.614) |
0.266 (0.398) |
1e-05 (8.6e-05) |
0.00178 (0.00724) |
0.0528 (0.11) |
0.295 (0.428) |
1e-05 (8.6e-05) |
0.00019 (0.00112) |
0.0191 (0.0497) |
0.00126 (0.0054) |
0.0123 (0.0359) |
0.00149 (0.00616) |
| 1q gain | 23 (4%) | 490 |
3e-05 (0.000226) |
0.00267 (0.0102) |
0.47 (0.618) |
0.833 (0.99) |
9e-05 (0.000607) |
0.00299 (0.0111) |
0.0188 (0.049) |
0.0304 (0.0719) |
0.0115 (0.0338) |
0.27 (0.403) |
||
| 5q gain | 9 (2%) | 504 |
0.00302 (0.0112) |
0.00832 (0.0256) |
0.44 (0.59) |
0.0614 (0.126) |
0.0011 (0.00479) |
0.00041 (0.00217) |
0.0819 (0.157) |
0.00613 (0.0203) |
0.00012 (0.000772) |
0.00076 (0.0036) |
||
| 8q gain | 55 (11%) | 458 |
0.0507 (0.107) |
0.406 (0.557) |
0.00021 (0.00121) |
5e-05 (0.000357) |
0.00758 (0.0237) |
0.0436 (0.0956) |
0.0014 (0.00589) |
0.00068 (0.0033) |
0.132 (0.228) |
0.0989 (0.181) |
0.0637 (0.128) |
0.0006 (0.00296) |
| 11p gain | 30 (6%) | 483 |
0.00432 (0.0153) |
0.0003 (0.00164) |
0.51 (0.66) |
0.158 (0.259) |
0.00681 (0.022) |
0.00857 (0.0263) |
0.0377 (0.0852) |
0.0265 (0.0647) |
0.126 (0.22) |
0.00749 (0.0235) |
||
| 18q gain | 13 (3%) | 500 |
0.00183 (0.00741) |
2e-05 (0.000156) |
0.451 (0.599) |
0.483 (0.63) |
0.00026 (0.00147) |
0.00048 (0.00244) |
0.525 (0.675) |
0.0174 (0.0462) |
0.0292 (0.0699) |
0.00679 (0.022) |
||
| 22q gain | 23 (4%) | 490 |
0.00086 (0.004) |
1e-05 (8.6e-05) |
0.75 (0.909) |
0.109 (0.197) |
0.00081 (0.00379) |
0.00048 (0.00244) |
0.0453 (0.0978) |
0.528 (0.679) |
0.00045 (0.00233) |
0.00177 (0.00723) |
||
| 8q loss | 11 (2%) | 502 |
3e-05 (0.000226) |
0.00092 (0.00418) |
0.0998 (0.182) |
0.105 (0.19) |
0.00018 (0.00107) |
0.00036 (0.00192) |
0.288 (0.423) |
0.0007 (0.00335) |
0.0498 (0.106) |
2e-05 (0.000156) |
||
| 11q loss | 21 (4%) | 492 |
2e-05 (0.000156) |
0.00018 (0.00107) |
0.133 (0.229) |
0.162 (0.265) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.0958 (0.177) |
0.0001 (0.000666) |
0.00631 (0.0208) |
0.00138 (0.00583) |
||
| 21q loss | 38 (7%) | 475 |
0.505 (0.654) |
0.00692 (0.0222) |
0.00013 (0.000815) |
5e-05 (0.000357) |
0.15 (0.25) |
0.457 (0.604) |
0.00129 (0.0055) |
1e-05 (8.6e-05) |
0.352 (0.496) |
0.0486 (0.103) |
0.126 (0.22) |
0.0254 (0.063) |
| xp loss | 99 (19%) | 414 |
0.84 (0.995) |
0.0662 (0.132) |
0.98 (1.00) |
0.00286 (0.0107) |
0.00246 (0.00945) |
0.00588 (0.0196) |
0.116 (0.206) |
1e-05 (8.6e-05) |
0.0238 (0.06) |
0.279 (0.414) |
0.00107 (0.00471) |
0.00033 (0.00178) |
| 2q gain | 13 (3%) | 500 |
0.00017 (0.00103) |
0.145 (0.243) |
0.251 (0.382) |
0.422 (0.573) |
0.04 (0.0897) |
0.00071 (0.00338) |
0.522 (0.673) |
0.017 (0.0455) |
0.0122 (0.0357) |
0.0282 (0.0677) |
||
| 4p gain | 12 (2%) | 501 |
0.00236 (0.00914) |
0.024 (0.0604) |
0.384 (0.535) |
0.48 (0.626) |
0.00716 (0.0228) |
0.0135 (0.0384) |
0.315 (0.453) |
0.0452 (0.0978) |
0.00313 (0.0114) |
0.0762 (0.149) |
||
| 8p gain | 45 (9%) | 468 |
0.00063 (0.00308) |
0.00328 (0.0119) |
0.0184 (0.0483) |
0.0616 (0.126) |
0.0166 (0.0448) |
0.0141 (0.0397) |
0.263 (0.395) |
0.344 (0.489) |
0.111 (0.199) |
0.00621 (0.0205) |
||
| 9q gain | 24 (5%) | 489 |
0.00689 (0.0222) |
0.00233 (0.0091) |
0.00694 (0.0222) |
0.866 (1.00) |
0.0433 (0.0955) |
0.00472 (0.0163) |
0.444 (0.593) |
0.0105 (0.0314) |
0.444 (0.593) |
0.0694 (0.137) |
||
| 12p gain | 32 (6%) | 481 |
0.754 (0.911) |
0.579 (0.738) |
4e-05 (0.00029) |
0.0259 (0.0639) |
0.177 (0.286) |
0.374 (0.523) |
0.0518 (0.109) |
0.0421 (0.0936) |
0.0477 (0.102) |
0.0278 (0.0672) |
0.117 (0.207) |
0.0227 (0.0577) |
| 15q gain | 11 (2%) | 502 |
0.011 (0.0326) |
0.0319 (0.0745) |
0.00893 (0.0271) |
0.0126 (0.0364) |
0.047 (0.101) |
0.063 (0.128) |
0.17 (0.276) |
0.288 (0.423) |
0.0197 (0.051) |
0.0576 (0.119) |
||
| 2q loss | 18 (4%) | 495 |
0.0153 (0.0425) |
0.00863 (0.0264) |
0.0479 (0.102) |
0.769 (0.926) |
0.455 (0.603) |
0.00186 (0.00747) |
0.0257 (0.0634) |
0.811 (0.969) |
0.143 (0.241) |
0.00206 (0.00817) |
||
| 6q loss | 63 (12%) | 450 |
1e-05 (8.6e-05) |
0.00097 (0.00436) |
0.457 (0.604) |
0.0339 (0.0789) |
0.0649 (0.13) |
0.0529 (0.11) |
0.00191 (0.00764) |
0.172 (0.278) |
0.0133 (0.0379) |
0.00451 (0.0156) |
||
| 12q loss | 52 (10%) | 461 |
1 (1.00) |
0.58 (0.738) |
1e-05 (8.6e-05) |
1e-05 (8.6e-05) |
0.604 (0.759) |
0.956 (1.00) |
0.00089 (0.00412) |
1e-05 (8.6e-05) |
0.00306 (0.0113) |
0.395 (0.546) |
0.24 (0.366) |
1e-05 (8.6e-05) |
| 15q loss | 51 (10%) | 462 |
1 (1.00) |
0.708 (0.868) |
0.0159 (0.0433) |
1e-05 (8.6e-05) |
0.0145 (0.0408) |
0.0871 (0.164) |
0.00276 (0.0105) |
3e-05 (0.000226) |
0.123 (0.216) |
0.473 (0.62) |
0.0937 (0.174) |
0.00053 (0.00266) |
| 2p gain | 14 (3%) | 499 |
6e-05 (0.000423) |
0.159 (0.26) |
0.251 (0.382) |
0.425 (0.575) |
0.0155 (0.0425) |
0.00166 (0.00681) |
0.645 (0.803) |
0.021 (0.0539) |
0.0045 (0.0156) |
0.0638 (0.128) |
||
| 4q gain | 7 (1%) | 506 |
0.00392 (0.014) |
0.0522 (0.109) |
0.0736 (0.144) |
0.728 (0.887) |
0.0053 (0.0179) |
0.00225 (0.00882) |
0.24 (0.366) |
0.0543 (0.113) |
0.0362 (0.0831) |
0.0355 (0.0821) |
||
| 10q gain | 11 (2%) | 502 |
0.0124 (0.0359) |
0.00116 (0.00503) |
0.0675 (0.134) |
0.0398 (0.0894) |
0.202 (0.318) |
0.00027 (0.00151) |
0.103 (0.187) |
0.0656 (0.131) |
0.738 (0.899) |
0.00148 (0.00615) |
||
| 12q gain | 15 (3%) | 498 |
2e-05 (0.000156) |
0.632 (0.79) |
0.0048 (0.0165) |
0.211 (0.329) |
0.00503 (0.0171) |
0.0926 (0.173) |
0.0565 (0.117) |
0.0279 (0.0672) |
0.0859 (0.163) |
0.0153 (0.0425) |
||
| 18p gain | 18 (4%) | 495 |
0.0065 (0.0213) |
0.00025 (0.00143) |
0.681 (0.842) |
0.939 (1.00) |
0.00563 (0.0189) |
0.022 (0.0562) |
0.936 (1.00) |
0.135 (0.231) |
0.236 (0.363) |
0.0226 (0.0577) |
||
| 5p loss | 35 (7%) | 478 |
0.745 (0.904) |
0.0668 (0.133) |
0.00049 (0.00247) |
0.00026 (0.00147) |
0.0902 (0.17) |
0.969 (1.00) |
0.0405 (0.0905) |
0.00106 (0.00468) |
0.112 (0.201) |
0.254 (0.385) |
0.181 (0.29) |
0.00013 (0.000815) |
| 9p loss | 118 (23%) | 395 |
0.385 (0.535) |
0.266 (0.398) |
1e-05 (8.6e-05) |
0.00409 (0.0146) |
0.00056 (0.00278) |
1e-05 (8.6e-05) |
0.104 (0.188) |
0.00015 (0.000935) |
0.972 (1.00) |
0.223 (0.344) |
0.371 (0.519) |
0.0851 (0.162) |
| 12p loss | 28 (5%) | 485 |
0.0149 (0.0416) |
0.0003 (0.00164) |
0.946 (1.00) |
1 (1.00) |
0.0987 (0.181) |
0.00507 (0.0172) |
0.0428 (0.0949) |
0.243 (0.371) |
0.486 (0.631) |
0.0477 (0.102) |
||
| 16q loss | 22 (4%) | 491 |
0.0056 (0.0188) |
0.0855 (0.162) |
0.294 (0.428) |
0.00567 (0.0189) |
0.0211 (0.054) |
0.0206 (0.0531) |
0.699 (0.861) |
0.00376 (0.0135) |
0.286 (0.421) |
0.128 (0.222) |
||
| 17p loss | 14 (3%) | 499 |
0.00094 (0.00425) |
0.0101 (0.0302) |
0.908 (1.00) |
0.616 (0.772) |
0.00049 (0.00247) |
0.0633 (0.128) |
0.0985 (0.181) |
0.00214 (0.00846) |
0.439 (0.589) |
0.0452 (0.0978) |
||
| 6p gain | 7 (1%) | 506 |
0.102 (0.186) |
0.00016 (0.000978) |
0.00818 (0.0253) |
0.43 (0.579) |
0.475 (0.622) |
0.00449 (0.0156) |
0.0261 (0.0642) |
0.066 (0.132) |
0.119 (0.209) |
0.115 (0.204) |
||
| 9p gain | 17 (3%) | 496 |
0.00499 (0.017) |
0.0305 (0.0719) |
0.0372 (0.0847) |
0.771 (0.927) |
0.0808 (0.156) |
0.0794 (0.153) |
0.882 (1.00) |
0.0279 (0.0672) |
0.987 (1.00) |
0.201 (0.317) |
||
| 11q gain | 58 (11%) | 455 |
0.613 (0.768) |
0.581 (0.738) |
1 (1.00) |
0.00414 (0.0147) |
0.203 (0.318) |
0.0673 (0.133) |
0.0463 (0.0998) |
0.0638 (0.128) |
0.392 (0.544) |
0.0468 (0.101) |
0.278 (0.413) |
0.0277 (0.0672) |
| 16q gain | 19 (4%) | 494 |
0.00679 (0.022) |
0.152 (0.252) |
0.636 (0.793) |
0.944 (1.00) |
0.0937 (0.174) |
0.00043 (0.00225) |
0.0485 (0.103) |
0.0996 (0.182) |
0.141 (0.238) |
0.0307 (0.0723) |
||
| xp gain | 22 (4%) | 491 |
0.00284 (0.0107) |
1e-05 (8.6e-05) |
0.404 (0.556) |
0.603 (0.759) |
0.0295 (0.0702) |
0.0187 (0.049) |
0.403 (0.554) |
0.74 (0.9) |
0.861 (1.00) |
0.198 (0.313) |
||
| 3p loss | 30 (6%) | 483 |
0.0231 (0.0584) |
0.151 (0.251) |
0.0113 (0.0335) |
0.0839 (0.16) |
0.0758 (0.148) |
0.0656 (0.131) |
0.00105 (0.00468) |
0.00039 (0.00207) |
0.0711 (0.14) |
0.13 (0.225) |
||
| 18q loss | 62 (12%) | 451 |
0.344 (0.489) |
0.149 (0.249) |
0.00091 (0.00417) |
0.00091 (0.00417) |
0.362 (0.508) |
0.0921 (0.173) |
0.0538 (0.112) |
0.0154 (0.0425) |
0.0181 (0.0477) |
0.712 (0.871) |
0.238 (0.364) |
0.287 (0.423) |
| 3q gain | 8 (2%) | 505 |
0.00012 (0.000772) |
0.467 (0.614) |
0.00439 (0.0154) |
0.21 (0.328) |
0.0715 (0.141) |
0.00434 (0.0153) |
0.387 (0.537) |
0.135 (0.231) |
0.839 (0.994) |
0.119 (0.209) |
||
| 2p loss | 21 (4%) | 492 |
0.0252 (0.0628) |
0.0351 (0.0813) |
0.101 (0.185) |
0.953 (1.00) |
0.18 (0.288) |
0.0439 (0.0961) |
0.0777 (0.151) |
0.399 (0.55) |
0.232 (0.357) |
0.137 (0.234) |
||
| 3q loss | 28 (5%) | 485 |
0.175 (0.283) |
0.881 (1.00) |
0.156 (0.256) |
0.14 (0.237) |
0.154 (0.255) |
0.0811 (0.156) |
0.148 (0.248) |
0.0317 (0.0742) |
0.095 (0.176) |
0.0165 (0.0446) |
0.112 (0.201) |
0.0158 (0.0432) |
| 16p loss | 14 (3%) | 499 |
0.0304 (0.0719) |
0.414 (0.565) |
0.704 (0.864) |
0.0632 (0.128) |
0.0375 (0.0852) |
0.0227 (0.0577) |
0.811 (0.969) |
0.356 (0.501) |
0.701 (0.862) |
0.326 (0.465) |
||
| 3p gain | 11 (2%) | 502 |
0.00062 (0.00304) |
0.281 (0.416) |
0.0764 (0.149) |
0.2 (0.316) |
0.111 (0.2) |
0.0369 (0.0843) |
0.133 (0.229) |
0.291 (0.425) |
0.425 (0.575) |
0.253 (0.384) |
||
| 16p gain | 16 (3%) | 497 |
0.119 (0.209) |
0.139 (0.237) |
0.564 (0.72) |
0.94 (1.00) |
0.158 (0.259) |
0.00235 (0.00914) |
0.155 (0.255) |
0.0502 (0.106) |
0.138 (0.235) |
0.0376 (0.0852) |
||
| 17p gain | 20 (4%) | 493 |
0.0128 (0.0368) |
0.122 (0.213) |
0.0162 (0.044) |
0.377 (0.526) |
0.206 (0.323) |
0.0638 (0.128) |
0.199 (0.314) |
0.485 (0.631) |
0.585 (0.739) |
0.371 (0.519) |
||
| 17q gain | 23 (4%) | 490 |
0.144 (0.242) |
0.548 (0.704) |
0.0126 (0.0363) |
0.0244 (0.0611) |
0.347 (0.491) |
0.257 (0.387) |
0.113 (0.202) |
0.701 (0.862) |
0.417 (0.569) |
0.11 (0.198) |
||
| 6p loss | 30 (6%) | 483 |
0.00018 (0.00107) |
0.18 (0.289) |
0.886 (1.00) |
0.349 (0.493) |
0.473 (0.62) |
0.155 (0.255) |
0.446 (0.593) |
0.405 (0.556) |
0.385 (0.535) |
0.0334 (0.0778) |
||
| 9q loss | 51 (10%) | 462 |
0.497 (0.644) |
0.743 (0.903) |
0.0852 (0.162) |
0.00451 (0.0156) |
0.584 (0.739) |
0.0441 (0.0963) |
0.42 (0.572) |
0.823 (0.981) |
0.894 (1.00) |
0.678 (0.839) |
||
| 17q loss | 9 (2%) | 504 |
0.00291 (0.0108) |
0.0533 (0.111) |
0.596 (0.751) |
0.229 (0.352) |
0.0109 (0.0324) |
0.295 (0.428) |
0.0819 (0.157) |
0.097 (0.179) |
0.424 (0.575) |
0.128 (0.222) |
||
| 18p loss | 67 (13%) | 446 |
0.323 (0.462) |
0.0302 (0.0717) |
0.00749 (0.0235) |
0.0756 (0.148) |
0.587 (0.741) |
0.113 (0.202) |
0.179 (0.288) |
0.0943 (0.175) |
0.287 (0.423) |
0.86 (1.00) |
0.558 (0.715) |
0.554 (0.71) |
| 20p loss | 7 (1%) | 506 |
0.0151 (0.0423) |
0.0369 (0.0843) |
0.655 (0.813) |
0.727 (0.887) |
0.291 (0.426) |
0.217 (0.336) |
0.429 (0.578) |
0.486 (0.631) |
0.751 (0.909) |
0.283 (0.418) |
||
| 20q loss | 3 (1%) | 510 |
0.32 (0.458) |
0.039 (0.0878) |
0.0345 (0.08) |
0.0779 (0.151) |
0.331 (0.472) |
1 (1.00) |
0.163 (0.266) |
0.196 (0.311) |
||||
| 14q gain | 4 (1%) | 509 |
0.205 (0.321) |
0.09 (0.17) |
0.792 (0.948) |
0.42 (0.572) |
0.754 (0.911) |
0.709 (0.868) |
0.196 (0.311) |
0.681 (0.842) |
1 (1.00) |
0.0245 (0.0611) |
||
| 21q gain | 23 (4%) | 490 |
0.00044 (0.00229) |
0.192 (0.304) |
0.215 (0.333) |
0.142 (0.241) |
0.634 (0.791) |
0.226 (0.348) |
0.26 (0.391) |
0.0622 (0.127) |
0.765 (0.923) |
0.177 (0.286) |
||
| 1q loss | 26 (5%) | 487 |
0.343 (0.488) |
0.15 (0.25) |
0.151 (0.251) |
0.132 (0.228) |
0.571 (0.729) |
0.119 (0.209) |
0.315 (0.453) |
0.00877 (0.0267) |
0.082 (0.157) |
0.293 (0.428) |
0.683 (0.843) |
0.295 (0.428) |
| 7q loss | 4 (1%) | 509 |
0.15 (0.25) |
0.442 (0.592) |
0.0169 (0.0455) |
0.254 (0.385) |
0.438 (0.589) |
0.0933 (0.174) |
1 (1.00) |
0.833 (0.99) |
0.561 (0.717) |
0.908 (1.00) |
||
| 19p loss | 26 (5%) | 487 |
0.847 (1.00) |
0.429 (0.578) |
0.933 (1.00) |
0.843 (0.997) |
0.352 (0.496) |
0.396 (0.547) |
0.677 (0.839) |
0.186 (0.295) |
0.214 (0.332) |
0.408 (0.558) |
0.0411 (0.0916) |
0.0961 (0.178) |
| 13q gain | 6 (1%) | 507 |
0.584 (0.739) |
0.181 (0.289) |
0.165 (0.268) |
0.144 (0.242) |
0.302 (0.436) |
0.48 (0.626) |
0.349 (0.493) |
0.585 (0.739) |
0.594 (0.748) |
0.95 (1.00) |
||
| 7p loss | 3 (1%) | 510 |
0.321 (0.459) |
0.649 (0.807) |
1 (1.00) |
0.792 (0.948) |
1 (1.00) |
1 (1.00) |
P value = 7e-05 (Fisher's exact test), Q value = 0.00048
Table S1. Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 1P GAIN MUTATED | 2 | 10 | 1 |
| 1P GAIN WILD-TYPE | 225 | 101 | 174 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00028 (Fisher's exact test), Q value = 0.0016
Table S2. Gene #1: '1p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 1P GAIN MUTATED | 3 | 8 | 0 | 2 |
| 1P GAIN WILD-TYPE | 206 | 126 | 157 | 11 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0233 (Fisher's exact test), Q value = 0.059
Table S3. Gene #1: '1p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 1P GAIN MUTATED | 2 | 5 | 1 | 0 |
| 1P GAIN WILD-TYPE | 89 | 90 | 124 | 115 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S4. Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 1P GAIN MUTATED | 0 | 13 | 0 | 0 | 0 |
| 1P GAIN WILD-TYPE | 130 | 102 | 105 | 133 | 30 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S5. Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 1P GAIN MUTATED | 0 | 8 | 0 | 0 | 0 | 5 | 0 |
| 1P GAIN WILD-TYPE | 135 | 63 | 36 | 68 | 90 | 36 | 72 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00656 (Fisher's exact test), Q value = 0.021
Table S6. Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 1P GAIN MUTATED | 8 | 4 | 0 | 1 |
| 1P GAIN WILD-TYPE | 132 | 103 | 82 | 179 |
Figure S6. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S7. Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 1P GAIN MUTATED | 3 | 0 | 10 |
| 1P GAIN WILD-TYPE | 219 | 184 | 93 |
Figure S7. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00291 (Fisher's exact test), Q value = 0.011
Table S8. Gene #1: '1p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 1P GAIN MUTATED | 4 | 8 | 0 | 1 |
| 1P GAIN WILD-TYPE | 123 | 111 | 105 | 153 |
Figure S8. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0011 (Fisher's exact test), Q value = 0.0048
Table S9. Gene #1: '1p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 1P GAIN MUTATED | 1 | 4 | 0 | 0 | 6 | 2 |
| 1P GAIN WILD-TYPE | 98 | 73 | 118 | 56 | 57 | 90 |
Figure S9. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S10. Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 1Q GAIN MUTATED | 4 | 15 | 4 |
| 1Q GAIN WILD-TYPE | 223 | 96 | 171 |
Figure S10. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00267 (Fisher's exact test), Q value = 0.01
Table S11. Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 1Q GAIN MUTATED | 7 | 12 | 2 | 2 |
| 1Q GAIN WILD-TYPE | 202 | 122 | 155 | 11 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00061
Table S12. Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 1Q GAIN MUTATED | 2 | 14 | 0 | 5 | 2 |
| 1Q GAIN WILD-TYPE | 128 | 101 | 105 | 128 | 28 |
Figure S12. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00299 (Fisher's exact test), Q value = 0.011
Table S13. Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 1Q GAIN MUTATED | 3 | 9 | 1 | 2 | 1 | 5 | 2 |
| 1Q GAIN WILD-TYPE | 132 | 62 | 35 | 66 | 89 | 36 | 70 |
Figure S13. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0188 (Fisher's exact test), Q value = 0.049
Table S14. Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 1Q GAIN MUTATED | 12 | 4 | 0 | 7 |
| 1Q GAIN WILD-TYPE | 128 | 103 | 82 | 173 |
Figure S14. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0304 (Fisher's exact test), Q value = 0.072
Table S15. Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 1Q GAIN MUTATED | 7 | 6 | 10 |
| 1Q GAIN WILD-TYPE | 215 | 178 | 93 |
Figure S15. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0115 (Fisher's exact test), Q value = 0.034
Table S16. Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 1Q GAIN MUTATED | 5 | 10 | 0 | 8 |
| 1Q GAIN WILD-TYPE | 122 | 109 | 105 | 146 |
Figure S16. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00042
Table S17. Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 2P GAIN MUTATED | 1 | 10 | 3 |
| 2P GAIN WILD-TYPE | 226 | 101 | 172 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0155 (Fisher's exact test), Q value = 0.043
Table S18. Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 2P GAIN MUTATED | 1 | 9 | 2 | 2 | 0 |
| 2P GAIN WILD-TYPE | 129 | 106 | 103 | 131 | 30 |
Figure S18. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00166 (Fisher's exact test), Q value = 0.0068
Table S19. Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 2P GAIN MUTATED | 0 | 5 | 1 | 2 | 2 | 4 | 0 |
| 2P GAIN WILD-TYPE | 135 | 66 | 35 | 66 | 88 | 37 | 72 |
Figure S19. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.021 (Fisher's exact test), Q value = 0.054
Table S20. Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 2P GAIN MUTATED | 5 | 2 | 7 |
| 2P GAIN WILD-TYPE | 217 | 182 | 96 |
Figure S20. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0045 (Fisher's exact test), Q value = 0.016
Table S21. Gene #3: '2p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 2P GAIN MUTATED | 2 | 9 | 0 | 3 |
| 2P GAIN WILD-TYPE | 125 | 110 | 105 | 151 |
Figure S21. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.001
Table S22. Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 2Q GAIN MUTATED | 1 | 9 | 3 |
| 2Q GAIN WILD-TYPE | 226 | 102 | 172 |
Figure S22. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.04 (Fisher's exact test), Q value = 0.09
Table S23. Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 2Q GAIN MUTATED | 1 | 8 | 2 | 2 | 0 |
| 2Q GAIN WILD-TYPE | 129 | 107 | 103 | 131 | 30 |
Figure S23. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00071 (Fisher's exact test), Q value = 0.0034
Table S24. Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 2Q GAIN MUTATED | 0 | 5 | 1 | 2 | 1 | 4 | 0 |
| 2Q GAIN WILD-TYPE | 135 | 66 | 35 | 66 | 89 | 37 | 72 |
Figure S24. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.017 (Fisher's exact test), Q value = 0.045
Table S25. Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 2Q GAIN MUTATED | 4 | 2 | 7 |
| 2Q GAIN WILD-TYPE | 218 | 182 | 96 |
Figure S25. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0122 (Fisher's exact test), Q value = 0.036
Table S26. Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 2Q GAIN MUTATED | 2 | 8 | 0 | 3 |
| 2Q GAIN WILD-TYPE | 125 | 111 | 105 | 151 |
Figure S26. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0282 (Fisher's exact test), Q value = 0.068
Table S27. Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 2Q GAIN MUTATED | 2 | 4 | 1 | 0 | 5 | 1 |
| 2Q GAIN WILD-TYPE | 97 | 73 | 117 | 56 | 58 | 91 |
Figure S27. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00062 (Fisher's exact test), Q value = 0.003
Table S28. Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 3P GAIN MUTATED | 2 | 8 | 1 |
| 3P GAIN WILD-TYPE | 225 | 103 | 174 |
Figure S28. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0369 (Fisher's exact test), Q value = 0.084
Table S29. Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 3P GAIN MUTATED | 2 | 4 | 2 | 0 | 0 | 2 | 1 |
| 3P GAIN WILD-TYPE | 133 | 67 | 34 | 68 | 90 | 39 | 71 |
Figure S29. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.00077
Table S30. Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 3Q GAIN MUTATED | 1 | 7 | 0 |
| 3Q GAIN WILD-TYPE | 226 | 104 | 175 |
Figure S30. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00439 (Fisher's exact test), Q value = 0.015
Table S31. Gene #6: '3q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 3Q GAIN MUTATED | 0 | 5 | 0 | 1 |
| 3Q GAIN WILD-TYPE | 91 | 90 | 125 | 114 |
Figure S31. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00434 (Fisher's exact test), Q value = 0.015
Table S32. Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 3Q GAIN MUTATED | 0 | 4 | 1 | 0 | 0 | 2 | 1 |
| 3Q GAIN WILD-TYPE | 135 | 67 | 35 | 68 | 90 | 39 | 71 |
Figure S32. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00236 (Fisher's exact test), Q value = 0.0091
Table S33. Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 4P GAIN MUTATED | 5 | 7 | 0 |
| 4P GAIN WILD-TYPE | 222 | 104 | 175 |
Figure S33. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.024 (Fisher's exact test), Q value = 0.06
Table S34. Gene #7: '4p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 4P GAIN MUTATED | 6 | 5 | 0 | 1 |
| 4P GAIN WILD-TYPE | 203 | 129 | 157 | 12 |
Figure S34. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00716 (Fisher's exact test), Q value = 0.023
Table S35. Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 4P GAIN MUTATED | 3 | 8 | 0 | 1 | 0 |
| 4P GAIN WILD-TYPE | 127 | 107 | 105 | 132 | 30 |
Figure S35. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0135 (Fisher's exact test), Q value = 0.038
Table S36. Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 4P GAIN MUTATED | 3 | 5 | 0 | 0 | 0 | 3 | 1 |
| 4P GAIN WILD-TYPE | 132 | 66 | 36 | 68 | 90 | 38 | 71 |
Figure S36. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0452 (Fisher's exact test), Q value = 0.098
Table S37. Gene #7: '4p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 4P GAIN MUTATED | 3 | 3 | 6 |
| 4P GAIN WILD-TYPE | 219 | 181 | 97 |
Figure S37. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00313 (Fisher's exact test), Q value = 0.011
Table S38. Gene #7: '4p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 4P GAIN MUTATED | 3 | 8 | 0 | 1 |
| 4P GAIN WILD-TYPE | 124 | 111 | 105 | 153 |
Figure S38. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00392 (Fisher's exact test), Q value = 0.014
Table S39. Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 4Q GAIN MUTATED | 2 | 5 | 0 |
| 4Q GAIN WILD-TYPE | 225 | 106 | 175 |
Figure S39. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0053 (Fisher's exact test), Q value = 0.018
Table S40. Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 4Q GAIN MUTATED | 0 | 6 | 0 | 1 | 0 |
| 4Q GAIN WILD-TYPE | 130 | 109 | 105 | 132 | 30 |
Figure S40. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00225 (Fisher's exact test), Q value = 0.0088
Table S41. Gene #8: '4q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 4Q GAIN MUTATED | 0 | 5 | 0 | 0 | 0 | 1 | 1 |
| 4Q GAIN WILD-TYPE | 135 | 66 | 36 | 68 | 90 | 40 | 71 |
Figure S41. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0362 (Fisher's exact test), Q value = 0.083
Table S42. Gene #8: '4q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 4Q GAIN MUTATED | 1 | 5 | 0 | 1 |
| 4Q GAIN WILD-TYPE | 126 | 114 | 105 | 153 |
Figure S42. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0355 (Fisher's exact test), Q value = 0.082
Table S43. Gene #8: '4q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 4Q GAIN MUTATED | 1 | 1 | 1 | 0 | 4 | 0 |
| 4Q GAIN WILD-TYPE | 98 | 76 | 117 | 56 | 59 | 92 |
Figure S43. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00132 (Fisher's exact test), Q value = 0.0056
Table S44. Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 5P GAIN MUTATED | 4 | 7 | 0 |
| 5P GAIN WILD-TYPE | 223 | 104 | 175 |
Figure S44. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0172 (Fisher's exact test), Q value = 0.046
Table S45. Gene #9: '5p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 5P GAIN MUTATED | 4 | 7 | 0 | 0 |
| 5P GAIN WILD-TYPE | 205 | 127 | 157 | 13 |
Figure S45. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.036 (Fisher's exact test), Q value = 0.083
Table S46. Gene #9: '5p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 5P GAIN MUTATED | 3 | 0 | 5 |
| 5P GAIN WILD-TYPE | 80 | 158 | 180 |
Figure S46. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.00077
Table S47. Gene #9: '5p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 5P GAIN MUTATED | 0 | 9 | 0 | 1 | 1 |
| 5P GAIN WILD-TYPE | 130 | 106 | 105 | 132 | 29 |
Figure S47. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00043 (Fisher's exact test), Q value = 0.0022
Table S48. Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 5P GAIN MUTATED | 1 | 7 | 0 | 1 | 0 | 2 | 0 |
| 5P GAIN WILD-TYPE | 134 | 64 | 36 | 67 | 90 | 39 | 72 |
Figure S48. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0257 (Fisher's exact test), Q value = 0.063
Table S49. Gene #9: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 5P GAIN MUTATED | 5 | 5 | 0 | 1 |
| 5P GAIN WILD-TYPE | 135 | 102 | 82 | 179 |
Figure S49. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0268 (Fisher's exact test), Q value = 0.065
Table S50. Gene #9: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 5P GAIN MUTATED | 3 | 2 | 6 |
| 5P GAIN WILD-TYPE | 219 | 182 | 97 |
Figure S50. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S51. Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 5P GAIN MUTATED | 0 | 10 | 0 | 1 |
| 5P GAIN WILD-TYPE | 127 | 109 | 105 | 153 |
Figure S51. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00078 (Fisher's exact test), Q value = 0.0037
Table S52. Gene #9: '5p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 5P GAIN MUTATED | 1 | 3 | 0 | 0 | 6 | 1 |
| 5P GAIN WILD-TYPE | 98 | 74 | 118 | 56 | 57 | 91 |
Figure S52. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00302 (Fisher's exact test), Q value = 0.011
Table S53. Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 5Q GAIN MUTATED | 3 | 6 | 0 |
| 5Q GAIN WILD-TYPE | 224 | 105 | 175 |
Figure S53. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00832 (Fisher's exact test), Q value = 0.026
Table S54. Gene #10: '5q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 5Q GAIN MUTATED | 2 | 7 | 0 | 0 |
| 5Q GAIN WILD-TYPE | 207 | 127 | 157 | 13 |
Figure S54. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0011 (Fisher's exact test), Q value = 0.0048
Table S55. Gene #10: '5q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 5Q GAIN MUTATED | 0 | 7 | 0 | 1 | 1 |
| 5Q GAIN WILD-TYPE | 130 | 108 | 105 | 132 | 29 |
Figure S55. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0022
Table S56. Gene #10: '5q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 5Q GAIN MUTATED | 1 | 7 | 0 | 1 | 0 | 0 | 0 |
| 5Q GAIN WILD-TYPE | 134 | 64 | 36 | 67 | 90 | 41 | 72 |
Figure S56. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00613 (Fisher's exact test), Q value = 0.02
Table S57. Gene #10: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 5Q GAIN MUTATED | 2 | 1 | 6 |
| 5Q GAIN WILD-TYPE | 220 | 183 | 97 |
Figure S57. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.00077
Table S58. Gene #10: '5q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 5Q GAIN MUTATED | 0 | 8 | 0 | 1 |
| 5Q GAIN WILD-TYPE | 127 | 111 | 105 | 153 |
Figure S58. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00076 (Fisher's exact test), Q value = 0.0036
Table S59. Gene #10: '5q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 5Q GAIN MUTATED | 1 | 1 | 0 | 0 | 6 | 1 |
| 5Q GAIN WILD-TYPE | 98 | 76 | 118 | 56 | 57 | 91 |
Figure S59. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.00098
Table S60. Gene #11: '6p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 6P GAIN MUTATED | 3 | 1 | 0 | 3 |
| 6P GAIN WILD-TYPE | 206 | 133 | 157 | 10 |
Figure S60. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00818 (Fisher's exact test), Q value = 0.025
Table S61. Gene #11: '6p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 6P GAIN MUTATED | 2 | 4 | 0 | 0 |
| 6P GAIN WILD-TYPE | 89 | 91 | 125 | 115 |
Figure S61. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00449 (Fisher's exact test), Q value = 0.016
Table S62. Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 6P GAIN MUTATED | 2 | 0 | 0 | 1 | 0 | 4 | 0 |
| 6P GAIN WILD-TYPE | 133 | 71 | 36 | 67 | 90 | 37 | 72 |
Figure S62. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0261 (Fisher's exact test), Q value = 0.064
Table S63. Gene #11: '6p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 6P GAIN MUTATED | 4 | 3 | 0 | 0 |
| 6P GAIN WILD-TYPE | 136 | 104 | 82 | 180 |
Figure S63. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S64. Gene #12: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 7P GAIN MUTATED | 42 | 66 | 12 |
| 7P GAIN WILD-TYPE | 185 | 45 | 163 |
Figure S64. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S65. Gene #12: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 7P GAIN MUTATED | 40 | 64 | 15 | 1 |
| 7P GAIN WILD-TYPE | 169 | 70 | 142 | 12 |
Figure S65. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0097 (Fisher's exact test), Q value = 0.029
Table S66. Gene #12: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 7P GAIN MUTATED | 22 | 32 | 20 | 20 |
| 7P GAIN WILD-TYPE | 69 | 63 | 105 | 95 |
Figure S66. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0179 (Fisher's exact test), Q value = 0.048
Table S67. Gene #12: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 7P GAIN MUTATED | 13 | 28 | 53 |
| 7P GAIN WILD-TYPE | 70 | 130 | 132 |
Figure S67. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S68. Gene #12: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 7P GAIN MUTATED | 22 | 59 | 9 | 24 | 6 |
| 7P GAIN WILD-TYPE | 108 | 56 | 96 | 109 | 24 |
Figure S68. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S69. Gene #12: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 7P GAIN MUTATED | 19 | 51 | 3 | 26 | 8 | 8 | 5 |
| 7P GAIN WILD-TYPE | 116 | 20 | 33 | 42 | 82 | 33 | 67 |
Figure S69. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00141 (Fisher's exact test), Q value = 0.0059
Table S70. Gene #12: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 7P GAIN MUTATED | 43 | 33 | 12 | 30 |
| 7P GAIN WILD-TYPE | 97 | 74 | 70 | 150 |
Figure S70. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S71. Gene #12: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 7P GAIN MUTATED | 37 | 26 | 55 |
| 7P GAIN WILD-TYPE | 185 | 158 | 48 |
Figure S71. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S72. Gene #12: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 7P GAIN MUTATED | 31 | 45 | 11 | 30 |
| 7P GAIN WILD-TYPE | 96 | 74 | 94 | 124 |
Figure S72. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S73. Gene #12: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 7P GAIN MUTATED | 15 | 11 | 17 | 7 | 47 | 20 |
| 7P GAIN WILD-TYPE | 84 | 66 | 101 | 49 | 16 | 72 |
Figure S73. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S74. Gene #13: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 7Q GAIN MUTATED | 57 | 73 | 20 |
| 7Q GAIN WILD-TYPE | 170 | 38 | 155 |
Figure S74. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S75. Gene #13: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 7Q GAIN MUTATED | 57 | 68 | 23 | 2 |
| 7Q GAIN WILD-TYPE | 152 | 66 | 134 | 11 |
Figure S75. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S76. Gene #13: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 7Q GAIN MUTATED | 35 | 63 | 12 | 32 | 8 |
| 7Q GAIN WILD-TYPE | 95 | 52 | 93 | 101 | 22 |
Figure S76. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S77. Gene #13: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 7Q GAIN MUTATED | 32 | 54 | 4 | 29 | 12 | 7 | 12 |
| 7Q GAIN WILD-TYPE | 103 | 17 | 32 | 39 | 78 | 34 | 60 |
Figure S77. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00285 (Fisher's exact test), Q value = 0.011
Table S78. Gene #13: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 7Q GAIN MUTATED | 49 | 41 | 15 | 43 |
| 7Q GAIN WILD-TYPE | 91 | 66 | 67 | 137 |
Figure S78. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S79. Gene #13: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 7Q GAIN MUTATED | 50 | 39 | 59 |
| 7Q GAIN WILD-TYPE | 172 | 145 | 44 |
Figure S79. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S80. Gene #13: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 7Q GAIN MUTATED | 38 | 53 | 14 | 42 |
| 7Q GAIN WILD-TYPE | 89 | 66 | 91 | 112 |
Figure S80. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S81. Gene #13: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 7Q GAIN MUTATED | 21 | 15 | 25 | 7 | 50 | 29 |
| 7Q GAIN WILD-TYPE | 78 | 62 | 93 | 49 | 13 | 63 |
Figure S81. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00063 (Fisher's exact test), Q value = 0.0031
Table S82. Gene #14: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 8P GAIN MUTATED | 24 | 16 | 5 |
| 8P GAIN WILD-TYPE | 203 | 95 | 170 |
Figure S82. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00328 (Fisher's exact test), Q value = 0.012
Table S83. Gene #14: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 8P GAIN MUTATED | 29 | 6 | 8 | 2 |
| 8P GAIN WILD-TYPE | 180 | 128 | 149 | 11 |
Figure S83. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0184 (Fisher's exact test), Q value = 0.048
Table S84. Gene #14: '8p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 8P GAIN MUTATED | 12 | 11 | 10 | 3 |
| 8P GAIN WILD-TYPE | 79 | 84 | 115 | 112 |
Figure S84. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0166 (Fisher's exact test), Q value = 0.045
Table S85. Gene #14: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 8P GAIN MUTATED | 20 | 8 | 4 | 9 | 4 |
| 8P GAIN WILD-TYPE | 110 | 107 | 101 | 124 | 26 |
Figure S85. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0141 (Fisher's exact test), Q value = 0.04
Table S86. Gene #14: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 8P GAIN MUTATED | 22 | 3 | 2 | 6 | 3 | 5 | 4 |
| 8P GAIN WILD-TYPE | 113 | 68 | 34 | 62 | 87 | 36 | 68 |
Figure S86. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00621 (Fisher's exact test), Q value = 0.021
Table S87. Gene #14: '8p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 8P GAIN MUTATED | 18 | 6 | 5 | 2 | 3 | 10 |
| 8P GAIN WILD-TYPE | 81 | 71 | 113 | 54 | 60 | 82 |
Figure S87. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0012
Table S88. Gene #15: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 8Q GAIN MUTATED | 32 | 17 | 6 |
| 8Q GAIN WILD-TYPE | 195 | 94 | 169 |
Figure S88. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00036
Table S89. Gene #15: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 8Q GAIN MUTATED | 38 | 7 | 8 | 2 |
| 8Q GAIN WILD-TYPE | 171 | 127 | 149 | 11 |
Figure S89. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00758 (Fisher's exact test), Q value = 0.024
Table S90. Gene #15: '8q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 8Q GAIN MUTATED | 14 | 14 | 11 | 4 |
| 8Q GAIN WILD-TYPE | 77 | 81 | 114 | 111 |
Figure S90. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0436 (Fisher's exact test), Q value = 0.096
Table S91. Gene #15: '8q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 8Q GAIN MUTATED | 12 | 9 | 22 |
| 8Q GAIN WILD-TYPE | 71 | 149 | 163 |
Figure S91. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0014 (Fisher's exact test), Q value = 0.0059
Table S92. Gene #15: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 8Q GAIN MUTATED | 26 | 9 | 4 | 12 | 4 |
| 8Q GAIN WILD-TYPE | 104 | 106 | 101 | 121 | 26 |
Figure S92. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00068 (Fisher's exact test), Q value = 0.0033
Table S93. Gene #15: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 8Q GAIN MUTATED | 27 | 3 | 2 | 9 | 3 | 6 | 5 |
| 8Q GAIN WILD-TYPE | 108 | 68 | 34 | 59 | 87 | 35 | 67 |
Figure S93. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-04 (Fisher's exact test), Q value = 0.003
Table S94. Gene #15: '8q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 8Q GAIN MUTATED | 21 | 8 | 6 | 2 | 3 | 14 |
| 8Q GAIN WILD-TYPE | 78 | 69 | 112 | 54 | 60 | 78 |
Figure S94. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00499 (Fisher's exact test), Q value = 0.017
Table S95. Gene #16: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 9P GAIN MUTATED | 8 | 8 | 1 |
| 9P GAIN WILD-TYPE | 219 | 103 | 174 |
Figure S95. Get High-res Image Gene #16: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0305 (Fisher's exact test), Q value = 0.072
Table S96. Gene #16: '9p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 9P GAIN MUTATED | 6 | 7 | 2 | 2 |
| 9P GAIN WILD-TYPE | 203 | 127 | 155 | 11 |
Figure S96. Get High-res Image Gene #16: '9p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0372 (Fisher's exact test), Q value = 0.085
Table S97. Gene #16: '9p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 9P GAIN MUTATED | 4 | 7 | 1 | 2 |
| 9P GAIN WILD-TYPE | 87 | 88 | 124 | 113 |
Figure S97. Get High-res Image Gene #16: '9p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0279 (Fisher's exact test), Q value = 0.067
Table S98. Gene #16: '9p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 9P GAIN MUTATED | 4 | 5 | 8 |
| 9P GAIN WILD-TYPE | 218 | 179 | 95 |
Figure S98. Get High-res Image Gene #16: '9p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00689 (Fisher's exact test), Q value = 0.022
Table S99. Gene #17: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 9Q GAIN MUTATED | 10 | 11 | 3 |
| 9Q GAIN WILD-TYPE | 217 | 100 | 172 |
Figure S99. Get High-res Image Gene #17: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00233 (Fisher's exact test), Q value = 0.0091
Table S100. Gene #17: '9q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 9Q GAIN MUTATED | 10 | 7 | 3 | 4 |
| 9Q GAIN WILD-TYPE | 199 | 127 | 154 | 9 |
Figure S100. Get High-res Image Gene #17: '9q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00694 (Fisher's exact test), Q value = 0.022
Table S101. Gene #17: '9q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 9Q GAIN MUTATED | 5 | 10 | 2 | 2 |
| 9Q GAIN WILD-TYPE | 86 | 85 | 123 | 113 |
Figure S101. Get High-res Image Gene #17: '9q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0433 (Fisher's exact test), Q value = 0.095
Table S102. Gene #17: '9q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 9Q GAIN MUTATED | 3 | 12 | 3 | 5 | 1 |
| 9Q GAIN WILD-TYPE | 127 | 103 | 102 | 128 | 29 |
Figure S102. Get High-res Image Gene #17: '9q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00472 (Fisher's exact test), Q value = 0.016
Table S103. Gene #17: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 9Q GAIN MUTATED | 3 | 5 | 1 | 5 | 2 | 7 | 1 |
| 9Q GAIN WILD-TYPE | 132 | 66 | 35 | 63 | 88 | 34 | 71 |
Figure S103. Get High-res Image Gene #17: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0105 (Fisher's exact test), Q value = 0.031
Table S104. Gene #17: '9q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 9Q GAIN MUTATED | 6 | 7 | 11 |
| 9Q GAIN WILD-TYPE | 216 | 177 | 92 |
Figure S104. Get High-res Image Gene #17: '9q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0423 (Fisher's exact test), Q value = 0.094
Table S105. Gene #18: '10p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 10P GAIN MUTATED | 0 | 3 | 0 | 0 |
| 10P GAIN WILD-TYPE | 7 | 4 | 7 | 6 |
Figure S105. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S106. Gene #18: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 10P GAIN MUTATED | 48 | 9 | 0 |
| 10P GAIN WILD-TYPE | 179 | 102 | 175 |
Figure S106. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S107. Gene #18: '10p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 10P GAIN MUTATED | 47 | 3 | 0 | 7 |
| 10P GAIN WILD-TYPE | 162 | 131 | 157 | 6 |
Figure S107. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00748 (Fisher's exact test), Q value = 0.023
Table S108. Gene #18: '10p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 10P GAIN MUTATED | 16 | 10 | 14 | 4 |
| 10P GAIN WILD-TYPE | 75 | 85 | 111 | 111 |
Figure S108. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00185 (Fisher's exact test), Q value = 0.0075
Table S109. Gene #18: '10p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 10P GAIN MUTATED | 15 | 7 | 22 |
| 10P GAIN WILD-TYPE | 68 | 151 | 163 |
Figure S109. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S110. Gene #18: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 10P GAIN MUTATED | 25 | 16 | 0 | 13 | 3 |
| 10P GAIN WILD-TYPE | 105 | 99 | 105 | 120 | 27 |
Figure S110. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S111. Gene #18: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 10P GAIN MUTATED | 29 | 0 | 0 | 11 | 0 | 14 | 3 |
| 10P GAIN WILD-TYPE | 106 | 71 | 36 | 57 | 90 | 27 | 69 |
Figure S111. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0273 (Fisher's exact test), Q value = 0.066
Table S112. Gene #18: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 10P GAIN MUTATED | 16 | 20 | 5 | 15 |
| 10P GAIN WILD-TYPE | 124 | 87 | 77 | 165 |
Figure S112. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0179 (Fisher's exact test), Q value = 0.048
Table S113. Gene #18: '10p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 10P GAIN MUTATED | 18 | 20 | 6 | 12 |
| 10P GAIN WILD-TYPE | 109 | 99 | 99 | 142 |
Figure S113. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S114. Gene #18: '10p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 10P GAIN MUTATED | 21 | 17 | 7 | 0 | 0 | 11 |
| 10P GAIN WILD-TYPE | 78 | 60 | 111 | 56 | 63 | 81 |
Figure S114. Get High-res Image Gene #18: '10p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0124 (Fisher's exact test), Q value = 0.036
Table S115. Gene #19: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 10Q GAIN MUTATED | 9 | 2 | 0 |
| 10Q GAIN WILD-TYPE | 218 | 109 | 175 |
Figure S115. Get High-res Image Gene #19: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00116 (Fisher's exact test), Q value = 0.005
Table S116. Gene #19: '10q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 10Q GAIN MUTATED | 8 | 1 | 0 | 2 |
| 10Q GAIN WILD-TYPE | 201 | 133 | 157 | 11 |
Figure S116. Get High-res Image Gene #19: '10q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0398 (Fisher's exact test), Q value = 0.089
Table S117. Gene #19: '10q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 10Q GAIN MUTATED | 1 | 1 | 9 |
| 10Q GAIN WILD-TYPE | 82 | 157 | 176 |
Figure S117. Get High-res Image Gene #19: '10q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00027 (Fisher's exact test), Q value = 0.0015
Table S118. Gene #19: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 10Q GAIN MUTATED | 2 | 0 | 0 | 4 | 0 | 5 | 0 |
| 10Q GAIN WILD-TYPE | 133 | 71 | 36 | 64 | 90 | 36 | 72 |
Figure S118. Get High-res Image Gene #19: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00148 (Fisher's exact test), Q value = 0.0061
Table S119. Gene #19: '10q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 10Q GAIN MUTATED | 0 | 7 | 2 | 0 | 0 | 2 |
| 10Q GAIN WILD-TYPE | 99 | 70 | 116 | 56 | 63 | 90 |
Figure S119. Get High-res Image Gene #19: '10q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00432 (Fisher's exact test), Q value = 0.015
Table S120. Gene #20: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 11P GAIN MUTATED | 5 | 10 | 15 |
| 11P GAIN WILD-TYPE | 222 | 101 | 160 |
Figure S120. Get High-res Image Gene #20: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0016
Table S121. Gene #20: '11p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 11P GAIN MUTATED | 8 | 2 | 20 | 0 |
| 11P GAIN WILD-TYPE | 201 | 132 | 137 | 13 |
Figure S121. Get High-res Image Gene #20: '11p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00681 (Fisher's exact test), Q value = 0.022
Table S122. Gene #20: '11p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 11P GAIN MUTATED | 7 | 1 | 13 | 7 | 2 |
| 11P GAIN WILD-TYPE | 123 | 114 | 92 | 126 | 28 |
Figure S122. Get High-res Image Gene #20: '11p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00857 (Fisher's exact test), Q value = 0.026
Table S123. Gene #20: '11p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 11P GAIN MUTATED | 6 | 0 | 6 | 3 | 9 | 1 | 5 |
| 11P GAIN WILD-TYPE | 129 | 71 | 30 | 65 | 81 | 40 | 67 |
Figure S123. Get High-res Image Gene #20: '11p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0377 (Fisher's exact test), Q value = 0.085
Table S124. Gene #20: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 11P GAIN MUTATED | 6 | 4 | 11 | 9 |
| 11P GAIN WILD-TYPE | 134 | 103 | 71 | 171 |
Figure S124. Get High-res Image Gene #20: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0265 (Fisher's exact test), Q value = 0.065
Table S125. Gene #20: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 11P GAIN MUTATED | 14 | 15 | 1 |
| 11P GAIN WILD-TYPE | 208 | 169 | 102 |
Figure S125. Get High-res Image Gene #20: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00749 (Fisher's exact test), Q value = 0.023
Table S126. Gene #20: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 11P GAIN MUTATED | 4 | 2 | 7 | 8 | 0 | 9 |
| 11P GAIN WILD-TYPE | 95 | 75 | 111 | 48 | 63 | 83 |
Figure S126. Get High-res Image Gene #20: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00414 (Fisher's exact test), Q value = 0.015
Table S127. Gene #21: '11q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 11Q GAIN MUTATED | 28 | 5 | 24 | 1 |
| 11Q GAIN WILD-TYPE | 181 | 129 | 133 | 12 |
Figure S127. Get High-res Image Gene #21: '11q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0463 (Fisher's exact test), Q value = 0.1
Table S128. Gene #21: '11q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 11Q GAIN MUTATED | 16 | 5 | 17 | 16 | 4 |
| 11Q GAIN WILD-TYPE | 114 | 110 | 88 | 117 | 26 |
Figure S128. Get High-res Image Gene #21: '11q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0468 (Fisher's exact test), Q value = 0.1
Table S129. Gene #21: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 11Q GAIN MUTATED | 30 | 23 | 5 |
| 11Q GAIN WILD-TYPE | 192 | 161 | 98 |
Figure S129. Get High-res Image Gene #21: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0277 (Fisher's exact test), Q value = 0.067
Table S130. Gene #21: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 11Q GAIN MUTATED | 12 | 8 | 12 | 10 | 1 | 15 |
| 11Q GAIN WILD-TYPE | 87 | 69 | 106 | 46 | 62 | 77 |
Figure S130. Get High-res Image Gene #21: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S131. Gene #22: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 12P GAIN MUTATED | 15 | 15 | 2 |
| 12P GAIN WILD-TYPE | 212 | 96 | 173 |
Figure S131. Get High-res Image Gene #22: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0259 (Fisher's exact test), Q value = 0.064
Table S132. Gene #22: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 12P GAIN MUTATED | 21 | 7 | 4 | 0 |
| 12P GAIN WILD-TYPE | 188 | 127 | 153 | 13 |
Figure S132. Get High-res Image Gene #22: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0421 (Fisher's exact test), Q value = 0.094
Table S133. Gene #22: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 12P GAIN MUTATED | 12 | 6 | 1 | 6 | 3 | 4 | 0 |
| 12P GAIN WILD-TYPE | 123 | 65 | 35 | 62 | 87 | 37 | 72 |
Figure S133. Get High-res Image Gene #22: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0477 (Fisher's exact test), Q value = 0.1
Table S134. Gene #22: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 12P GAIN MUTATED | 11 | 11 | 5 | 5 |
| 12P GAIN WILD-TYPE | 129 | 96 | 77 | 175 |
Figure S134. Get High-res Image Gene #22: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0278 (Fisher's exact test), Q value = 0.067
Table S135. Gene #22: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 12P GAIN MUTATED | 17 | 5 | 10 |
| 12P GAIN WILD-TYPE | 205 | 179 | 93 |
Figure S135. Get High-res Image Gene #22: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0227 (Fisher's exact test), Q value = 0.058
Table S136. Gene #22: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 12P GAIN MUTATED | 6 | 7 | 1 | 3 | 5 | 10 |
| 12P GAIN WILD-TYPE | 93 | 70 | 117 | 53 | 58 | 82 |
Figure S136. Get High-res Image Gene #22: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S137. Gene #23: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 12Q GAIN MUTATED | 4 | 11 | 0 |
| 12Q GAIN WILD-TYPE | 223 | 100 | 175 |
Figure S137. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0048 (Fisher's exact test), Q value = 0.016
Table S138. Gene #23: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 12Q GAIN MUTATED | 3 | 8 | 1 | 1 |
| 12Q GAIN WILD-TYPE | 88 | 87 | 124 | 114 |
Figure S138. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00503 (Fisher's exact test), Q value = 0.017
Table S139. Gene #23: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 12Q GAIN MUTATED | 4 | 9 | 2 | 0 | 0 |
| 12Q GAIN WILD-TYPE | 126 | 106 | 103 | 133 | 30 |
Figure S139. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0279 (Fisher's exact test), Q value = 0.067
Table S140. Gene #23: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 12Q GAIN MUTATED | 6 | 2 | 7 |
| 12Q GAIN WILD-TYPE | 216 | 182 | 96 |
Figure S140. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0153 (Fisher's exact test), Q value = 0.043
Table S141. Gene #23: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 12Q GAIN MUTATED | 2 | 2 | 0 | 2 | 6 | 3 |
| 12Q GAIN WILD-TYPE | 97 | 75 | 118 | 54 | 57 | 89 |
Figure S141. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0245 (Fisher's exact test), Q value = 0.061
Table S142. Gene #25: '14q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 14Q GAIN MUTATED | 0 | 0 | 0 | 2 | 0 | 2 |
| 14Q GAIN WILD-TYPE | 99 | 77 | 118 | 54 | 63 | 90 |
Figure S142. Get High-res Image Gene #25: '14q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.011 (Fisher's exact test), Q value = 0.033
Table S143. Gene #26: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 15Q GAIN MUTATED | 6 | 5 | 0 |
| 15Q GAIN WILD-TYPE | 221 | 106 | 175 |
Figure S143. Get High-res Image Gene #26: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0319 (Fisher's exact test), Q value = 0.074
Table S144. Gene #26: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 15Q GAIN MUTATED | 7 | 3 | 0 | 1 |
| 15Q GAIN WILD-TYPE | 202 | 131 | 157 | 12 |
Figure S144. Get High-res Image Gene #26: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00893 (Fisher's exact test), Q value = 0.027
Table S145. Gene #26: '15q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 15Q GAIN MUTATED | 0 | 4 | 6 | 0 |
| 15Q GAIN WILD-TYPE | 91 | 91 | 119 | 115 |
Figure S145. Get High-res Image Gene #26: '15q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0126 (Fisher's exact test), Q value = 0.036
Table S146. Gene #26: '15q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 15Q GAIN MUTATED | 0 | 1 | 9 |
| 15Q GAIN WILD-TYPE | 83 | 157 | 176 |
Figure S146. Get High-res Image Gene #26: '15q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.047 (Fisher's exact test), Q value = 0.1
Table S147. Gene #26: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 15Q GAIN MUTATED | 4 | 6 | 0 | 1 | 0 |
| 15Q GAIN WILD-TYPE | 126 | 109 | 105 | 132 | 30 |
Figure S147. Get High-res Image Gene #26: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0197 (Fisher's exact test), Q value = 0.051
Table S148. Gene #26: '15q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 15Q GAIN MUTATED | 4 | 6 | 0 | 1 |
| 15Q GAIN WILD-TYPE | 123 | 113 | 105 | 153 |
Figure S148. Get High-res Image Gene #26: '15q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00235 (Fisher's exact test), Q value = 0.0091
Table S149. Gene #27: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 16P GAIN MUTATED | 1 | 1 | 2 | 3 | 1 | 6 | 2 |
| 16P GAIN WILD-TYPE | 134 | 70 | 34 | 65 | 89 | 35 | 70 |
Figure S149. Get High-res Image Gene #27: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0376 (Fisher's exact test), Q value = 0.085
Table S150. Gene #27: '16p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 16P GAIN MUTATED | 1 | 5 | 4 | 0 | 0 | 6 |
| 16P GAIN WILD-TYPE | 98 | 72 | 114 | 56 | 63 | 86 |
Figure S150. Get High-res Image Gene #27: '16p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00679 (Fisher's exact test), Q value = 0.022
Table S151. Gene #28: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 16Q GAIN MUTATED | 6 | 10 | 3 |
| 16Q GAIN WILD-TYPE | 221 | 101 | 172 |
Figure S151. Get High-res Image Gene #28: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00043 (Fisher's exact test), Q value = 0.0022
Table S152. Gene #28: '16q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 16Q GAIN MUTATED | 2 | 1 | 1 | 3 | 1 | 8 | 3 |
| 16Q GAIN WILD-TYPE | 133 | 70 | 35 | 65 | 89 | 33 | 69 |
Figure S152. Get High-res Image Gene #28: '16q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0485 (Fisher's exact test), Q value = 0.1
Table S153. Gene #28: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 16Q GAIN MUTATED | 1 | 7 | 2 | 9 |
| 16Q GAIN WILD-TYPE | 139 | 100 | 80 | 171 |
Figure S153. Get High-res Image Gene #28: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0307 (Fisher's exact test), Q value = 0.072
Table S154. Gene #28: '16q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 16Q GAIN MUTATED | 2 | 7 | 5 | 0 | 0 | 5 |
| 16Q GAIN WILD-TYPE | 97 | 70 | 113 | 56 | 63 | 87 |
Figure S154. Get High-res Image Gene #28: '16q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0128 (Fisher's exact test), Q value = 0.037
Table S155. Gene #29: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 17P GAIN MUTATED | 5 | 10 | 5 |
| 17P GAIN WILD-TYPE | 222 | 101 | 170 |
Figure S155. Get High-res Image Gene #29: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0162 (Fisher's exact test), Q value = 0.044
Table S156. Gene #29: '17p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 17P GAIN MUTATED | 3 | 8 | 2 | 1 |
| 17P GAIN WILD-TYPE | 88 | 87 | 123 | 114 |
Figure S156. Get High-res Image Gene #29: '17p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0126 (Fisher's exact test), Q value = 0.036
Table S157. Gene #30: '17q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 17Q GAIN MUTATED | 5 | 8 | 2 | 1 |
| 17Q GAIN WILD-TYPE | 86 | 87 | 123 | 114 |
Figure S157. Get High-res Image Gene #30: '17q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0244 (Fisher's exact test), Q value = 0.061
Table S158. Gene #30: '17q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 17Q GAIN MUTATED | 7 | 2 | 7 |
| 17Q GAIN WILD-TYPE | 76 | 156 | 178 |
Figure S158. Get High-res Image Gene #30: '17q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0065 (Fisher's exact test), Q value = 0.021
Table S159. Gene #31: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 18P GAIN MUTATED | 9 | 8 | 1 |
| 18P GAIN WILD-TYPE | 218 | 103 | 174 |
Figure S159. Get High-res Image Gene #31: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00025 (Fisher's exact test), Q value = 0.0014
Table S160. Gene #31: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 18P GAIN MUTATED | 8 | 5 | 1 | 4 |
| 18P GAIN WILD-TYPE | 201 | 129 | 156 | 9 |
Figure S160. Get High-res Image Gene #31: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00563 (Fisher's exact test), Q value = 0.019
Table S161. Gene #31: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 18P GAIN MUTATED | 2 | 8 | 0 | 5 | 3 |
| 18P GAIN WILD-TYPE | 128 | 107 | 105 | 128 | 27 |
Figure S161. Get High-res Image Gene #31: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.022 (Fisher's exact test), Q value = 0.056
Table S162. Gene #31: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 18P GAIN MUTATED | 4 | 4 | 0 | 3 | 0 | 5 | 2 |
| 18P GAIN WILD-TYPE | 131 | 67 | 36 | 65 | 90 | 36 | 70 |
Figure S162. Get High-res Image Gene #31: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0226 (Fisher's exact test), Q value = 0.058
Table S163. Gene #31: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 18P GAIN MUTATED | 2 | 8 | 2 | 0 | 3 | 3 |
| 18P GAIN WILD-TYPE | 97 | 69 | 116 | 56 | 60 | 89 |
Figure S163. Get High-res Image Gene #31: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00183 (Fisher's exact test), Q value = 0.0074
Table S164. Gene #32: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 18Q GAIN MUTATED | 6 | 7 | 0 |
| 18Q GAIN WILD-TYPE | 221 | 104 | 175 |
Figure S164. Get High-res Image Gene #32: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S165. Gene #32: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 18Q GAIN MUTATED | 3 | 6 | 0 | 4 |
| 18Q GAIN WILD-TYPE | 206 | 128 | 157 | 9 |
Figure S165. Get High-res Image Gene #32: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0015
Table S166. Gene #32: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 18Q GAIN MUTATED | 1 | 9 | 0 | 1 | 2 |
| 18Q GAIN WILD-TYPE | 129 | 106 | 105 | 132 | 28 |
Figure S166. Get High-res Image Gene #32: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00048 (Fisher's exact test), Q value = 0.0024
Table S167. Gene #32: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 18Q GAIN MUTATED | 2 | 5 | 0 | 0 | 0 | 5 | 1 |
| 18Q GAIN WILD-TYPE | 133 | 66 | 36 | 68 | 90 | 36 | 71 |
Figure S167. Get High-res Image Gene #32: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0174 (Fisher's exact test), Q value = 0.046
Table S168. Gene #32: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 18Q GAIN MUTATED | 4 | 2 | 7 |
| 18Q GAIN WILD-TYPE | 218 | 182 | 96 |
Figure S168. Get High-res Image Gene #32: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0292 (Fisher's exact test), Q value = 0.07
Table S169. Gene #32: '18q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 18Q GAIN MUTATED | 2 | 8 | 1 | 2 |
| 18Q GAIN WILD-TYPE | 125 | 111 | 104 | 152 |
Figure S169. Get High-res Image Gene #32: '18q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00679 (Fisher's exact test), Q value = 0.022
Table S170. Gene #32: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 18Q GAIN MUTATED | 1 | 6 | 1 | 0 | 4 | 1 |
| 18Q GAIN WILD-TYPE | 98 | 71 | 117 | 56 | 59 | 91 |
Figure S170. Get High-res Image Gene #32: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S171. Gene #33: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 19P GAIN MUTATED | 20 | 25 | 54 |
| 19P GAIN WILD-TYPE | 207 | 86 | 121 |
Figure S171. Get High-res Image Gene #33: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S172. Gene #33: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 19P GAIN MUTATED | 10 | 30 | 59 | 0 |
| 19P GAIN WILD-TYPE | 199 | 104 | 98 | 13 |
Figure S172. Get High-res Image Gene #33: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00389 (Fisher's exact test), Q value = 0.014
Table S173. Gene #33: '19p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 19P GAIN MUTATED | 10 | 24 | 50 |
| 19P GAIN WILD-TYPE | 73 | 134 | 135 |
Figure S173. Get High-res Image Gene #33: '19p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S174. Gene #33: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 19P GAIN MUTATED | 5 | 30 | 42 | 21 | 1 |
| 19P GAIN WILD-TYPE | 125 | 85 | 63 | 112 | 29 |
Figure S174. Get High-res Image Gene #33: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S175. Gene #33: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 19P GAIN MUTATED | 6 | 25 | 14 | 7 | 30 | 3 | 14 |
| 19P GAIN WILD-TYPE | 129 | 46 | 22 | 61 | 60 | 38 | 58 |
Figure S175. Get High-res Image Gene #33: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0024 (Fisher's exact test), Q value = 0.0093
Table S176. Gene #33: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 19P GAIN MUTATED | 21 | 18 | 29 | 31 |
| 19P GAIN WILD-TYPE | 119 | 89 | 53 | 149 |
Figure S176. Get High-res Image Gene #33: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.0012
Table S177. Gene #33: '19p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 19P GAIN MUTATED | 14 | 24 | 36 | 25 |
| 19P GAIN WILD-TYPE | 113 | 95 | 69 | 129 |
Figure S177. Get High-res Image Gene #33: '19p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S178. Gene #33: '19p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 19P GAIN MUTATED | 8 | 9 | 21 | 24 | 23 | 14 |
| 19P GAIN WILD-TYPE | 91 | 68 | 97 | 32 | 40 | 78 |
Figure S178. Get High-res Image Gene #33: '19p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S179. Gene #34: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 19Q GAIN MUTATED | 11 | 14 | 0 |
| 19Q GAIN WILD-TYPE | 216 | 97 | 175 |
Figure S179. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S180. Gene #34: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 19Q GAIN MUTATED | 2 | 23 | 0 | 0 |
| 19Q GAIN WILD-TYPE | 207 | 111 | 157 | 13 |
Figure S180. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0138 (Fisher's exact test), Q value = 0.039
Table S181. Gene #34: '19q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 19Q GAIN MUTATED | 1 | 3 | 14 |
| 19Q GAIN WILD-TYPE | 82 | 155 | 171 |
Figure S181. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S182. Gene #34: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 19Q GAIN MUTATED | 1 | 19 | 0 | 4 | 1 |
| 19Q GAIN WILD-TYPE | 129 | 96 | 105 | 129 | 29 |
Figure S182. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S183. Gene #34: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 19Q GAIN MUTATED | 2 | 19 | 0 | 4 | 0 | 0 | 0 |
| 19Q GAIN WILD-TYPE | 133 | 52 | 36 | 64 | 90 | 41 | 72 |
Figure S183. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00247 (Fisher's exact test), Q value = 0.0095
Table S184. Gene #34: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 19Q GAIN MUTATED | 7 | 12 | 0 | 6 |
| 19Q GAIN WILD-TYPE | 133 | 95 | 82 | 174 |
Figure S184. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S185. Gene #34: '19q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 19Q GAIN MUTATED | 3 | 2 | 20 |
| 19Q GAIN WILD-TYPE | 219 | 182 | 83 |
Figure S185. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00082
Table S186. Gene #34: '19q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 19Q GAIN MUTATED | 7 | 14 | 0 | 4 |
| 19Q GAIN WILD-TYPE | 120 | 105 | 105 | 150 |
Figure S186. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S187. Gene #34: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 19Q GAIN MUTATED | 2 | 0 | 3 | 0 | 19 | 1 |
| 19Q GAIN WILD-TYPE | 97 | 77 | 115 | 56 | 44 | 91 |
Figure S187. Get High-res Image Gene #34: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S188. Gene #35: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 20P GAIN MUTATED | 15 | 28 | 2 |
| 20P GAIN WILD-TYPE | 212 | 83 | 173 |
Figure S188. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S189. Gene #35: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 20P GAIN MUTATED | 6 | 31 | 6 | 2 |
| 20P GAIN WILD-TYPE | 203 | 103 | 151 | 11 |
Figure S189. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00484 (Fisher's exact test), Q value = 0.017
Table S190. Gene #35: '20p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 20P GAIN MUTATED | 9 | 17 | 7 | 5 |
| 20P GAIN WILD-TYPE | 82 | 78 | 118 | 110 |
Figure S190. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0154 (Fisher's exact test), Q value = 0.043
Table S191. Gene #35: '20p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 20P GAIN MUTATED | 5 | 8 | 25 |
| 20P GAIN WILD-TYPE | 78 | 150 | 160 |
Figure S191. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S192. Gene #35: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 20P GAIN MUTATED | 3 | 30 | 3 | 8 | 1 |
| 20P GAIN WILD-TYPE | 127 | 85 | 102 | 125 | 29 |
Figure S192. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S193. Gene #35: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 20P GAIN MUTATED | 3 | 23 | 2 | 8 | 2 | 5 | 2 |
| 20P GAIN WILD-TYPE | 132 | 48 | 34 | 60 | 88 | 36 | 70 |
Figure S193. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S194. Gene #35: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 20P GAIN MUTATED | 9 | 10 | 26 |
| 20P GAIN WILD-TYPE | 213 | 174 | 77 |
Figure S194. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00027 (Fisher's exact test), Q value = 0.0015
Table S195. Gene #35: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 20P GAIN MUTATED | 14 | 19 | 1 | 11 |
| 20P GAIN WILD-TYPE | 113 | 100 | 104 | 143 |
Figure S195. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S196. Gene #35: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 20P GAIN MUTATED | 4 | 4 | 9 | 2 | 21 | 5 |
| 20P GAIN WILD-TYPE | 95 | 73 | 109 | 54 | 42 | 87 |
Figure S196. Get High-res Image Gene #35: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S197. Gene #36: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 20Q GAIN MUTATED | 16 | 26 | 2 |
| 20Q GAIN WILD-TYPE | 211 | 85 | 173 |
Figure S197. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S198. Gene #36: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 20Q GAIN MUTATED | 6 | 30 | 6 | 2 |
| 20Q GAIN WILD-TYPE | 203 | 104 | 151 | 11 |
Figure S198. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 7e-04 (Fisher's exact test), Q value = 0.0034
Table S199. Gene #36: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 20Q GAIN MUTATED | 9 | 17 | 7 | 3 |
| 20Q GAIN WILD-TYPE | 82 | 78 | 118 | 112 |
Figure S199. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00369 (Fisher's exact test), Q value = 0.013
Table S200. Gene #36: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 20Q GAIN MUTATED | 5 | 6 | 25 |
| 20Q GAIN WILD-TYPE | 78 | 152 | 160 |
Figure S200. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S201. Gene #36: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 20Q GAIN MUTATED | 4 | 30 | 3 | 6 | 1 |
| 20Q GAIN WILD-TYPE | 126 | 85 | 102 | 127 | 29 |
Figure S201. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S202. Gene #36: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 20Q GAIN MUTATED | 4 | 23 | 2 | 7 | 2 | 5 | 1 |
| 20Q GAIN WILD-TYPE | 131 | 48 | 34 | 61 | 88 | 36 | 71 |
Figure S202. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0452 (Fisher's exact test), Q value = 0.098
Table S203. Gene #36: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 20Q GAIN MUTATED | 17 | 13 | 3 | 11 |
| 20Q GAIN WILD-TYPE | 123 | 94 | 79 | 169 |
Figure S203. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S204. Gene #36: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 20Q GAIN MUTATED | 10 | 8 | 26 |
| 20Q GAIN WILD-TYPE | 212 | 176 | 77 |
Figure S204. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00061
Table S205. Gene #36: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 20Q GAIN MUTATED | 16 | 18 | 1 | 9 |
| 20Q GAIN WILD-TYPE | 111 | 101 | 104 | 145 |
Figure S205. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S206. Gene #36: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 20Q GAIN MUTATED | 6 | 3 | 7 | 2 | 21 | 5 |
| 20Q GAIN WILD-TYPE | 93 | 74 | 111 | 54 | 42 | 87 |
Figure S206. Get High-res Image Gene #36: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00044 (Fisher's exact test), Q value = 0.0023
Table S207. Gene #37: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 21Q GAIN MUTATED | 4 | 13 | 6 |
| 21Q GAIN WILD-TYPE | 223 | 98 | 169 |
Figure S207. Get High-res Image Gene #37: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00086 (Fisher's exact test), Q value = 0.004
Table S208. Gene #38: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 22Q GAIN MUTATED | 3 | 4 | 16 |
| 22Q GAIN WILD-TYPE | 224 | 107 | 159 |
Figure S208. Get High-res Image Gene #38: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S209. Gene #38: '22q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 22Q GAIN MUTATED | 1 | 3 | 18 | 1 |
| 22Q GAIN WILD-TYPE | 208 | 131 | 139 | 12 |
Figure S209. Get High-res Image Gene #38: '22q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00081 (Fisher's exact test), Q value = 0.0038
Table S210. Gene #38: '22q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 22Q GAIN MUTATED | 1 | 4 | 13 | 5 | 0 |
| 22Q GAIN WILD-TYPE | 129 | 111 | 92 | 128 | 30 |
Figure S210. Get High-res Image Gene #38: '22q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00048 (Fisher's exact test), Q value = 0.0024
Table S211. Gene #38: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 22Q GAIN MUTATED | 0 | 2 | 6 | 2 | 7 | 2 | 4 |
| 22Q GAIN WILD-TYPE | 135 | 69 | 30 | 66 | 83 | 39 | 68 |
Figure S211. Get High-res Image Gene #38: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0453 (Fisher's exact test), Q value = 0.098
Table S212. Gene #38: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 22Q GAIN MUTATED | 4 | 3 | 9 | 7 |
| 22Q GAIN WILD-TYPE | 136 | 104 | 73 | 173 |
Figure S212. Get High-res Image Gene #38: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0023
Table S213. Gene #38: '22q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 22Q GAIN MUTATED | 1 | 2 | 12 | 8 |
| 22Q GAIN WILD-TYPE | 126 | 117 | 93 | 146 |
Figure S213. Get High-res Image Gene #38: '22q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00177 (Fisher's exact test), Q value = 0.0072
Table S214. Gene #38: '22q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 22Q GAIN MUTATED | 1 | 1 | 3 | 7 | 2 | 9 |
| 22Q GAIN WILD-TYPE | 98 | 76 | 115 | 49 | 61 | 83 |
Figure S214. Get High-res Image Gene #38: '22q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00284 (Fisher's exact test), Q value = 0.011
Table S215. Gene #39: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| XP GAIN MUTATED | 13 | 8 | 1 |
| XP GAIN WILD-TYPE | 214 | 103 | 174 |
Figure S215. Get High-res Image Gene #39: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S216. Gene #39: 'xp gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| XP GAIN MUTATED | 18 | 2 | 0 | 2 |
| XP GAIN WILD-TYPE | 191 | 132 | 157 | 11 |
Figure S216. Get High-res Image Gene #39: 'xp gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0295 (Fisher's exact test), Q value = 0.07
Table S217. Gene #39: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| XP GAIN MUTATED | 10 | 4 | 0 | 7 | 1 |
| XP GAIN WILD-TYPE | 120 | 111 | 105 | 126 | 29 |
Figure S217. Get High-res Image Gene #39: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0187 (Fisher's exact test), Q value = 0.049
Table S218. Gene #39: 'xp gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| XP GAIN MUTATED | 9 | 2 | 0 | 7 | 0 | 2 | 2 |
| XP GAIN WILD-TYPE | 126 | 69 | 36 | 61 | 90 | 39 | 70 |
Figure S218. Get High-res Image Gene #39: 'xp gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S219. Gene #40: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| XQ GAIN MUTATED | 29 | 12 | 1 |
| XQ GAIN WILD-TYPE | 198 | 99 | 174 |
Figure S219. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S220. Gene #40: 'xq gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| XQ GAIN MUTATED | 34 | 6 | 0 | 2 |
| XQ GAIN WILD-TYPE | 175 | 128 | 157 | 11 |
Figure S220. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0262 (Fisher's exact test), Q value = 0.064
Table S221. Gene #40: 'xq gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| XQ GAIN MUTATED | 10 | 7 | 15 | 3 |
| XQ GAIN WILD-TYPE | 81 | 88 | 110 | 112 |
Figure S221. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0249 (Fisher's exact test), Q value = 0.062
Table S222. Gene #40: 'xq gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| XQ GAIN MUTATED | 10 | 6 | 19 |
| XQ GAIN WILD-TYPE | 73 | 152 | 166 |
Figure S222. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00082
Table S223. Gene #40: 'xq gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| XQ GAIN MUTATED | 18 | 9 | 0 | 10 | 5 |
| XQ GAIN WILD-TYPE | 112 | 106 | 105 | 123 | 25 |
Figure S223. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S224. Gene #40: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| XQ GAIN MUTATED | 24 | 3 | 0 | 8 | 0 | 4 | 3 |
| XQ GAIN WILD-TYPE | 111 | 68 | 36 | 60 | 90 | 37 | 69 |
Figure S224. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0101 (Fisher's exact test), Q value = 0.03
Table S225. Gene #40: 'xq gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| XQ GAIN MUTATED | 18 | 10 | 1 | 12 |
| XQ GAIN WILD-TYPE | 122 | 97 | 81 | 168 |
Figure S225. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0366 (Fisher's exact test), Q value = 0.084
Table S226. Gene #40: 'xq gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| XQ GAIN MUTATED | 15 | 13 | 3 | 10 |
| XQ GAIN WILD-TYPE | 112 | 106 | 102 | 144 |
Figure S226. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00196 (Fisher's exact test), Q value = 0.0078
Table S227. Gene #40: 'xq gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| XQ GAIN MUTATED | 16 | 7 | 5 | 0 | 3 | 10 |
| XQ GAIN WILD-TYPE | 83 | 70 | 113 | 56 | 60 | 82 |
Figure S227. Get High-res Image Gene #40: 'xq gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.029 (Fisher's exact test), Q value = 0.069
Table S228. Gene #41: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 9 | 10 | 8 |
| 1P LOSS MUTATED | 1 | 7 | 2 |
| 1P LOSS WILD-TYPE | 8 | 3 | 6 |
Figure S228. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00098
Table S229. Gene #41: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 1P LOSS MUTATED | 0 | 1 | 7 | 2 |
| 1P LOSS WILD-TYPE | 7 | 6 | 0 | 4 |
Figure S229. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S230. Gene #41: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 1P LOSS MUTATED | 7 | 12 | 165 |
| 1P LOSS WILD-TYPE | 220 | 99 | 10 |
Figure S230. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S231. Gene #41: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 1P LOSS MUTATED | 5 | 23 | 156 | 0 |
| 1P LOSS WILD-TYPE | 204 | 111 | 1 | 13 |
Figure S231. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00312 (Fisher's exact test), Q value = 0.011
Table S232. Gene #41: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 1P LOSS MUTATED | 24 | 31 | 47 | 58 |
| 1P LOSS WILD-TYPE | 67 | 64 | 78 | 57 |
Figure S232. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00106 (Fisher's exact test), Q value = 0.0047
Table S233. Gene #41: '1p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 1P LOSS MUTATED | 23 | 77 | 60 |
| 1P LOSS WILD-TYPE | 60 | 81 | 125 |
Figure S233. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S234. Gene #41: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 1P LOSS MUTATED | 3 | 10 | 104 | 58 | 9 |
| 1P LOSS WILD-TYPE | 127 | 105 | 1 | 75 | 21 |
Figure S234. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S235. Gene #41: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 1P LOSS MUTATED | 3 | 6 | 36 | 1 | 87 | 1 | 50 |
| 1P LOSS WILD-TYPE | 132 | 65 | 0 | 67 | 3 | 40 | 22 |
Figure S235. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S236. Gene #41: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 1P LOSS MUTATED | 27 | 8 | 68 | 81 |
| 1P LOSS WILD-TYPE | 113 | 99 | 14 | 99 |
Figure S236. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S237. Gene #41: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 1P LOSS MUTATED | 80 | 97 | 7 |
| 1P LOSS WILD-TYPE | 142 | 87 | 96 |
Figure S237. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S238. Gene #41: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 1P LOSS MUTATED | 16 | 17 | 83 | 68 |
| 1P LOSS WILD-TYPE | 111 | 102 | 22 | 86 |
Figure S238. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S239. Gene #41: '1p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 1P LOSS MUTATED | 6 | 25 | 59 | 55 | 4 | 35 |
| 1P LOSS WILD-TYPE | 93 | 52 | 59 | 1 | 59 | 57 |
Figure S239. Get High-res Image Gene #41: '1p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00877 (Fisher's exact test), Q value = 0.027
Table S240. Gene #42: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 1Q LOSS MUTATED | 4 | 3 | 5 | 0 | 5 | 1 | 8 |
| 1Q LOSS WILD-TYPE | 131 | 68 | 31 | 68 | 85 | 40 | 64 |
Figure S240. Get High-res Image Gene #42: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0252 (Fisher's exact test), Q value = 0.063
Table S241. Gene #43: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 2P LOSS MUTATED | 14 | 5 | 2 |
| 2P LOSS WILD-TYPE | 213 | 106 | 173 |
Figure S241. Get High-res Image Gene #43: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0351 (Fisher's exact test), Q value = 0.081
Table S242. Gene #43: '2p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 2P LOSS MUTATED | 11 | 6 | 2 | 2 |
| 2P LOSS WILD-TYPE | 198 | 128 | 155 | 11 |
Figure S242. Get High-res Image Gene #43: '2p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0439 (Fisher's exact test), Q value = 0.096
Table S243. Gene #43: '2p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 2P LOSS MUTATED | 6 | 4 | 0 | 2 | 2 | 6 | 1 |
| 2P LOSS WILD-TYPE | 129 | 67 | 36 | 66 | 88 | 35 | 71 |
Figure S243. Get High-res Image Gene #43: '2p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0153 (Fisher's exact test), Q value = 0.043
Table S244. Gene #44: '2q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 2Q LOSS MUTATED | 14 | 2 | 2 |
| 2Q LOSS WILD-TYPE | 213 | 109 | 173 |
Figure S244. Get High-res Image Gene #44: '2q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00863 (Fisher's exact test), Q value = 0.026
Table S245. Gene #44: '2q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 2Q LOSS MUTATED | 12 | 2 | 2 | 2 |
| 2Q LOSS WILD-TYPE | 197 | 132 | 155 | 11 |
Figure S245. Get High-res Image Gene #44: '2q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0479 (Fisher's exact test), Q value = 0.1
Table S246. Gene #44: '2q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 2Q LOSS MUTATED | 2 | 9 | 3 | 3 |
| 2Q LOSS WILD-TYPE | 89 | 86 | 122 | 112 |
Figure S246. Get High-res Image Gene #44: '2q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00186 (Fisher's exact test), Q value = 0.0075
Table S247. Gene #44: '2q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 2Q LOSS MUTATED | 5 | 1 | 0 | 3 | 2 | 7 | 0 |
| 2Q LOSS WILD-TYPE | 130 | 70 | 36 | 65 | 88 | 34 | 72 |
Figure S247. Get High-res Image Gene #44: '2q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0257 (Fisher's exact test), Q value = 0.063
Table S248. Gene #44: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 2Q LOSS MUTATED | 3 | 9 | 2 | 3 |
| 2Q LOSS WILD-TYPE | 137 | 98 | 80 | 177 |
Figure S248. Get High-res Image Gene #44: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00206 (Fisher's exact test), Q value = 0.0082
Table S249. Gene #44: '2q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 2Q LOSS MUTATED | 1 | 9 | 2 | 1 | 0 | 3 |
| 2Q LOSS WILD-TYPE | 98 | 68 | 116 | 55 | 63 | 89 |
Figure S249. Get High-res Image Gene #44: '2q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0231 (Fisher's exact test), Q value = 0.058
Table S250. Gene #45: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 3P LOSS MUTATED | 13 | 12 | 5 |
| 3P LOSS WILD-TYPE | 214 | 99 | 170 |
Figure S250. Get High-res Image Gene #45: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.033
Table S251. Gene #45: '3p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 3P LOSS MUTATED | 4 | 13 | 6 | 3 |
| 3P LOSS WILD-TYPE | 87 | 82 | 119 | 112 |
Figure S251. Get High-res Image Gene #45: '3p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00105 (Fisher's exact test), Q value = 0.0047
Table S252. Gene #45: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 3P LOSS MUTATED | 9 | 14 | 4 | 3 |
| 3P LOSS WILD-TYPE | 131 | 93 | 78 | 177 |
Figure S252. Get High-res Image Gene #45: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00039 (Fisher's exact test), Q value = 0.0021
Table S253. Gene #45: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 3P LOSS MUTATED | 18 | 2 | 10 |
| 3P LOSS WILD-TYPE | 204 | 182 | 93 |
Figure S253. Get High-res Image Gene #45: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0317 (Fisher's exact test), Q value = 0.074
Table S254. Gene #46: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 3Q LOSS MUTATED | 9 | 4 | 1 | 4 | 2 | 7 | 1 |
| 3Q LOSS WILD-TYPE | 126 | 67 | 35 | 64 | 88 | 34 | 71 |
Figure S254. Get High-res Image Gene #46: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0165 (Fisher's exact test), Q value = 0.045
Table S255. Gene #46: '3q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 3Q LOSS MUTATED | 14 | 4 | 10 |
| 3Q LOSS WILD-TYPE | 208 | 180 | 93 |
Figure S255. Get High-res Image Gene #46: '3q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0158 (Fisher's exact test), Q value = 0.043
Table S256. Gene #46: '3q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 3Q LOSS MUTATED | 8 | 10 | 2 | 2 | 2 | 3 |
| 3Q LOSS WILD-TYPE | 91 | 67 | 116 | 54 | 61 | 89 |
Figure S256. Get High-res Image Gene #46: '3q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S257. Gene #47: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 4P LOSS MUTATED | 12 | 16 | 44 |
| 4P LOSS WILD-TYPE | 215 | 95 | 131 |
Figure S257. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S258. Gene #47: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 4P LOSS MUTATED | 24 | 3 | 44 | 1 |
| 4P LOSS WILD-TYPE | 185 | 131 | 113 | 12 |
Figure S258. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0118 (Fisher's exact test), Q value = 0.034
Table S259. Gene #47: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 4P LOSS MUTATED | 6 | 21 | 20 | 12 |
| 4P LOSS WILD-TYPE | 85 | 74 | 105 | 103 |
Figure S259. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 0.00077
Table S260. Gene #47: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 4P LOSS MUTATED | 16 | 6 | 29 | 18 | 3 |
| 4P LOSS WILD-TYPE | 114 | 109 | 76 | 115 | 27 |
Figure S260. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S261. Gene #47: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 4P LOSS MUTATED | 14 | 2 | 14 | 7 | 23 | 3 | 9 |
| 4P LOSS WILD-TYPE | 121 | 69 | 22 | 61 | 67 | 38 | 63 |
Figure S261. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00048
Table S262. Gene #47: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 4P LOSS MUTATED | 13 | 12 | 26 | 21 |
| 4P LOSS WILD-TYPE | 127 | 95 | 56 | 159 |
Figure S262. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00105 (Fisher's exact test), Q value = 0.0047
Table S263. Gene #47: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 4P LOSS MUTATED | 39 | 29 | 4 |
| 4P LOSS WILD-TYPE | 183 | 155 | 99 |
Figure S263. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00056 (Fisher's exact test), Q value = 0.0028
Table S264. Gene #47: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 4P LOSS MUTATED | 11 | 11 | 28 | 22 |
| 4P LOSS WILD-TYPE | 116 | 108 | 77 | 132 |
Figure S264. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S265. Gene #47: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 4P LOSS MUTATED | 7 | 13 | 13 | 18 | 1 | 20 |
| 4P LOSS WILD-TYPE | 92 | 64 | 105 | 38 | 62 | 72 |
Figure S265. Get High-res Image Gene #47: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S266. Gene #48: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 4Q LOSS MUTATED | 24 | 21 | 49 |
| 4Q LOSS WILD-TYPE | 203 | 90 | 126 |
Figure S266. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S267. Gene #48: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 4Q LOSS MUTATED | 37 | 8 | 47 | 2 |
| 4Q LOSS WILD-TYPE | 172 | 126 | 110 | 11 |
Figure S267. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0186 (Fisher's exact test), Q value = 0.049
Table S268. Gene #48: '4q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 4Q LOSS MUTATED | 8 | 25 | 23 | 21 |
| 4Q LOSS WILD-TYPE | 83 | 70 | 102 | 94 |
Figure S268. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00119 (Fisher's exact test), Q value = 0.0051
Table S269. Gene #48: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 4Q LOSS MUTATED | 22 | 11 | 31 | 28 | 2 |
| 4Q LOSS WILD-TYPE | 108 | 104 | 74 | 105 | 28 |
Figure S269. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S270. Gene #48: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 4Q LOSS MUTATED | 19 | 2 | 15 | 11 | 24 | 8 | 15 |
| 4Q LOSS WILD-TYPE | 116 | 69 | 21 | 57 | 66 | 33 | 57 |
Figure S270. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00047 (Fisher's exact test), Q value = 0.0024
Table S271. Gene #48: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 4Q LOSS MUTATED | 14 | 18 | 27 | 35 |
| 4Q LOSS WILD-TYPE | 126 | 89 | 55 | 145 |
Figure S271. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00347 (Fisher's exact test), Q value = 0.013
Table S272. Gene #48: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 4Q LOSS MUTATED | 45 | 41 | 8 |
| 4Q LOSS WILD-TYPE | 177 | 143 | 95 |
Figure S272. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0072 (Fisher's exact test), Q value = 0.023
Table S273. Gene #48: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 4Q LOSS MUTATED | 16 | 16 | 30 | 32 |
| 4Q LOSS WILD-TYPE | 111 | 103 | 75 | 122 |
Figure S273. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S274. Gene #48: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 4Q LOSS MUTATED | 9 | 18 | 20 | 18 | 2 | 27 |
| 4Q LOSS WILD-TYPE | 90 | 59 | 98 | 38 | 61 | 65 |
Figure S274. Get High-res Image Gene #48: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00049 (Fisher's exact test), Q value = 0.0025
Table S275. Gene #49: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 5P LOSS MUTATED | 18 | 14 | 3 |
| 5P LOSS WILD-TYPE | 209 | 97 | 172 |
Figure S275. Get High-res Image Gene #49: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0015
Table S276. Gene #49: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 5P LOSS MUTATED | 24 | 7 | 2 | 2 |
| 5P LOSS WILD-TYPE | 185 | 127 | 155 | 11 |
Figure S276. Get High-res Image Gene #49: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0405 (Fisher's exact test), Q value = 0.091
Table S277. Gene #49: '5p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 5P LOSS MUTATED | 10 | 11 | 1 | 11 | 2 |
| 5P LOSS WILD-TYPE | 120 | 104 | 104 | 122 | 28 |
Figure S277. Get High-res Image Gene #49: '5p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00106 (Fisher's exact test), Q value = 0.0047
Table S278. Gene #49: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 5P LOSS MUTATED | 10 | 2 | 0 | 8 | 2 | 9 | 4 |
| 5P LOSS WILD-TYPE | 125 | 69 | 36 | 60 | 88 | 32 | 68 |
Figure S278. Get High-res Image Gene #49: '5p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00082
Table S279. Gene #49: '5p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 5P LOSS MUTATED | 3 | 15 | 6 | 0 | 2 | 9 |
| 5P LOSS WILD-TYPE | 96 | 62 | 112 | 56 | 61 | 83 |
Figure S279. Get High-res Image Gene #49: '5p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00081 (Fisher's exact test), Q value = 0.0038
Table S280. Gene #50: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 5Q LOSS MUTATED | 20 | 10 | 2 |
| 5Q LOSS WILD-TYPE | 207 | 101 | 173 |
Figure S280. Get High-res Image Gene #50: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S281. Gene #50: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 5Q LOSS MUTATED | 21 | 5 | 2 | 4 |
| 5Q LOSS WILD-TYPE | 188 | 129 | 155 | 9 |
Figure S281. Get High-res Image Gene #50: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0022 (Fisher's exact test), Q value = 0.0087
Table S282. Gene #50: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 5Q LOSS MUTATED | 6 | 14 | 6 | 2 |
| 5Q LOSS WILD-TYPE | 85 | 81 | 119 | 113 |
Figure S282. Get High-res Image Gene #50: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.039
Table S283. Gene #50: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 5Q LOSS MUTATED | 10 | 13 | 1 | 6 | 2 |
| 5Q LOSS WILD-TYPE | 120 | 102 | 104 | 127 | 28 |
Figure S283. Get High-res Image Gene #50: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S284. Gene #50: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 5Q LOSS MUTATED | 9 | 2 | 0 | 6 | 2 | 12 | 1 |
| 5Q LOSS WILD-TYPE | 126 | 69 | 36 | 62 | 88 | 29 | 71 |
Figure S284. Get High-res Image Gene #50: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00067
Table S285. Gene #50: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 5Q LOSS MUTATED | 5 | 18 | 2 | 7 |
| 5Q LOSS WILD-TYPE | 135 | 89 | 80 | 173 |
Figure S285. Get High-res Image Gene #50: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0155 (Fisher's exact test), Q value = 0.043
Table S286. Gene #50: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 5Q LOSS MUTATED | 12 | 12 | 2 | 6 |
| 5Q LOSS WILD-TYPE | 115 | 107 | 103 | 148 |
Figure S286. Get High-res Image Gene #50: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S287. Gene #50: '5q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 5Q LOSS MUTATED | 4 | 14 | 2 | 0 | 2 | 10 |
| 5Q LOSS WILD-TYPE | 95 | 63 | 116 | 56 | 61 | 82 |
Figure S287. Get High-res Image Gene #50: '5q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00018 (Fisher's exact test), Q value = 0.0011
Table S288. Gene #51: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 6P LOSS MUTATED | 10 | 16 | 4 |
| 6P LOSS WILD-TYPE | 217 | 95 | 171 |
Figure S288. Get High-res Image Gene #51: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0334 (Fisher's exact test), Q value = 0.078
Table S289. Gene #51: '6p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 6P LOSS MUTATED | 6 | 2 | 4 | 3 | 10 | 4 |
| 6P LOSS WILD-TYPE | 93 | 75 | 114 | 53 | 53 | 88 |
Figure S289. Get High-res Image Gene #51: '6p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S290. Gene #52: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 6Q LOSS MUTATED | 23 | 35 | 5 |
| 6Q LOSS WILD-TYPE | 204 | 76 | 170 |
Figure S290. Get High-res Image Gene #52: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00097 (Fisher's exact test), Q value = 0.0044
Table S291. Gene #52: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 6Q LOSS MUTATED | 32 | 21 | 7 | 3 |
| 6Q LOSS WILD-TYPE | 177 | 113 | 150 | 10 |
Figure S291. Get High-res Image Gene #52: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0339 (Fisher's exact test), Q value = 0.079
Table S292. Gene #52: '6q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 6Q LOSS MUTATED | 8 | 14 | 33 |
| 6Q LOSS WILD-TYPE | 75 | 144 | 152 |
Figure S292. Get High-res Image Gene #52: '6q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00191 (Fisher's exact test), Q value = 0.0076
Table S293. Gene #52: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 6Q LOSS MUTATED | 29 | 14 | 4 | 16 |
| 6Q LOSS WILD-TYPE | 111 | 93 | 78 | 164 |
Figure S293. Get High-res Image Gene #52: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0133 (Fisher's exact test), Q value = 0.038
Table S294. Gene #52: '6q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 6Q LOSS MUTATED | 22 | 18 | 5 | 16 |
| 6Q LOSS WILD-TYPE | 105 | 101 | 100 | 138 |
Figure S294. Get High-res Image Gene #52: '6q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00451 (Fisher's exact test), Q value = 0.016
Table S295. Gene #52: '6q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 6Q LOSS MUTATED | 20 | 5 | 11 | 4 | 14 | 7 |
| 6Q LOSS WILD-TYPE | 79 | 72 | 107 | 52 | 49 | 85 |
Figure S295. Get High-res Image Gene #52: '6q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0169 (Fisher's exact test), Q value = 0.045
Table S296. Gene #54: '7q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 7Q LOSS MUTATED | 0 | 0 | 4 | 0 |
| 7Q LOSS WILD-TYPE | 91 | 95 | 121 | 115 |
Figure S296. Get High-res Image Gene #54: '7q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0435 (Fisher's exact test), Q value = 0.096
Table S297. Gene #55: '8p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 8P LOSS MUTATED | 0 | 3 | 0 | 0 |
| 8P LOSS WILD-TYPE | 7 | 4 | 7 | 6 |
Figure S297. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S298. Gene #55: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 8P LOSS MUTATED | 5 | 12 | 0 |
| 8P LOSS WILD-TYPE | 222 | 99 | 175 |
Figure S298. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.0012
Table S299. Gene #55: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 8P LOSS MUTATED | 5 | 10 | 0 | 2 |
| 8P LOSS WILD-TYPE | 204 | 124 | 157 | 11 |
Figure S299. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0161 (Fisher's exact test), Q value = 0.044
Table S300. Gene #55: '8p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 8P LOSS MUTATED | 0 | 8 | 4 | 3 |
| 8P LOSS WILD-TYPE | 91 | 87 | 121 | 112 |
Figure S300. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0102 (Fisher's exact test), Q value = 0.031
Table S301. Gene #55: '8p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 8P LOSS MUTATED | 0 | 3 | 12 |
| 8P LOSS WILD-TYPE | 83 | 155 | 173 |
Figure S301. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S302. Gene #55: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 8P LOSS MUTATED | 0 | 13 | 0 | 3 | 1 |
| 8P LOSS WILD-TYPE | 130 | 102 | 105 | 130 | 29 |
Figure S302. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S303. Gene #55: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 8P LOSS MUTATED | 1 | 8 | 0 | 2 | 0 | 5 | 1 |
| 8P LOSS WILD-TYPE | 134 | 63 | 36 | 66 | 90 | 36 | 71 |
Figure S303. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00146 (Fisher's exact test), Q value = 0.0061
Table S304. Gene #55: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 8P LOSS MUTATED | 7 | 1 | 9 |
| 8P LOSS WILD-TYPE | 215 | 183 | 94 |
Figure S304. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00782 (Fisher's exact test), Q value = 0.024
Table S305. Gene #55: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 8P LOSS MUTATED | 2 | 10 | 1 | 3 |
| 8P LOSS WILD-TYPE | 125 | 109 | 104 | 151 |
Figure S305. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S306. Gene #55: '8p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 8P LOSS MUTATED | 1 | 6 | 1 | 0 | 8 | 0 |
| 8P LOSS WILD-TYPE | 98 | 71 | 117 | 56 | 55 | 92 |
Figure S306. Get High-res Image Gene #55: '8p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S307. Gene #56: '8q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 8Q LOSS MUTATED | 2 | 9 | 0 |
| 8Q LOSS WILD-TYPE | 225 | 102 | 175 |
Figure S307. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00092 (Fisher's exact test), Q value = 0.0042
Table S308. Gene #56: '8q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 8Q LOSS MUTATED | 2 | 9 | 0 | 0 |
| 8Q LOSS WILD-TYPE | 207 | 125 | 157 | 13 |
Figure S308. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0011
Table S309. Gene #56: '8q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 8Q LOSS MUTATED | 0 | 9 | 0 | 1 | 1 |
| 8Q LOSS WILD-TYPE | 130 | 106 | 105 | 132 | 29 |
Figure S309. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0019
Table S310. Gene #56: '8q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 8Q LOSS MUTATED | 1 | 7 | 0 | 1 | 0 | 2 | 0 |
| 8Q LOSS WILD-TYPE | 134 | 64 | 36 | 67 | 90 | 39 | 72 |
Figure S310. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 7e-04 (Fisher's exact test), Q value = 0.0034
Table S311. Gene #56: '8q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 8Q LOSS MUTATED | 4 | 0 | 7 |
| 8Q LOSS WILD-TYPE | 218 | 184 | 96 |
Figure S311. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0498 (Fisher's exact test), Q value = 0.11
Table S312. Gene #56: '8q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 8Q LOSS MUTATED | 2 | 6 | 0 | 2 |
| 8Q LOSS WILD-TYPE | 125 | 113 | 105 | 152 |
Figure S312. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S313. Gene #56: '8q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 8Q LOSS MUTATED | 0 | 3 | 0 | 0 | 7 | 0 |
| 8Q LOSS WILD-TYPE | 99 | 74 | 118 | 56 | 56 | 92 |
Figure S313. Get High-res Image Gene #56: '8q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S314. Gene #57: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 9P LOSS MUTATED | 49 | 47 | 22 |
| 9P LOSS WILD-TYPE | 178 | 64 | 153 |
Figure S314. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00409 (Fisher's exact test), Q value = 0.015
Table S315. Gene #57: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 9P LOSS MUTATED | 58 | 35 | 21 | 4 |
| 9P LOSS WILD-TYPE | 151 | 99 | 136 | 9 |
Figure S315. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00056 (Fisher's exact test), Q value = 0.0028
Table S316. Gene #57: '9p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 9P LOSS MUTATED | 13 | 37 | 29 | 22 |
| 9P LOSS WILD-TYPE | 78 | 58 | 96 | 93 |
Figure S316. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S317. Gene #57: '9p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 9P LOSS MUTATED | 9 | 27 | 65 |
| 9P LOSS WILD-TYPE | 74 | 131 | 120 |
Figure S317. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00015 (Fisher's exact test), Q value = 0.00093
Table S318. Gene #57: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 9P LOSS MUTATED | 33 | 21 | 9 | 25 | 10 | 13 | 7 |
| 9P LOSS WILD-TYPE | 102 | 50 | 27 | 43 | 80 | 28 | 65 |
Figure S318. Get High-res Image Gene #57: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00451 (Fisher's exact test), Q value = 0.016
Table S319. Gene #58: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 9Q LOSS MUTATED | 3 | 12 | 29 |
| 9Q LOSS WILD-TYPE | 80 | 146 | 156 |
Figure S319. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0441 (Fisher's exact test), Q value = 0.096
Table S320. Gene #58: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 9Q LOSS MUTATED | 11 | 11 | 7 | 7 | 7 | 6 | 2 |
| 9Q LOSS WILD-TYPE | 124 | 60 | 29 | 61 | 83 | 35 | 70 |
Figure S320. Get High-res Image Gene #58: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S321. Gene #59: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 10P LOSS MUTATED | 23 | 54 | 6 |
| 10P LOSS WILD-TYPE | 204 | 57 | 169 |
Figure S321. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S322. Gene #59: '10p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 10P LOSS MUTATED | 4 | 73 | 6 | 0 |
| 10P LOSS WILD-TYPE | 205 | 61 | 151 | 13 |
Figure S322. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00742 (Fisher's exact test), Q value = 0.023
Table S323. Gene #59: '10p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 10P LOSS MUTATED | 10 | 24 | 11 | 16 |
| 10P LOSS WILD-TYPE | 81 | 71 | 114 | 99 |
Figure S323. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0017
Table S324. Gene #59: '10p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 10P LOSS MUTATED | 4 | 17 | 40 |
| 10P LOSS WILD-TYPE | 79 | 141 | 145 |
Figure S324. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S325. Gene #59: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 10P LOSS MUTATED | 1 | 64 | 1 | 13 | 4 |
| 10P LOSS WILD-TYPE | 129 | 51 | 104 | 120 | 26 |
Figure S325. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S326. Gene #59: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 10P LOSS MUTATED | 1 | 60 | 3 | 12 | 3 | 4 | 0 |
| 10P LOSS WILD-TYPE | 134 | 11 | 33 | 56 | 87 | 37 | 72 |
Figure S326. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.00098
Table S327. Gene #59: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 10P LOSS MUTATED | 32 | 26 | 5 | 20 |
| 10P LOSS WILD-TYPE | 108 | 81 | 77 | 160 |
Figure S327. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S328. Gene #59: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 10P LOSS MUTATED | 11 | 12 | 60 |
| 10P LOSS WILD-TYPE | 211 | 172 | 43 |
Figure S328. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S329. Gene #59: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 10P LOSS MUTATED | 26 | 37 | 3 | 17 |
| 10P LOSS WILD-TYPE | 101 | 82 | 102 | 137 |
Figure S329. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S330. Gene #59: '10p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 10P LOSS MUTATED | 4 | 6 | 12 | 1 | 55 | 5 |
| 10P LOSS WILD-TYPE | 95 | 71 | 106 | 55 | 8 | 87 |
Figure S330. Get High-res Image Gene #59: '10p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S331. Gene #60: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 10Q LOSS MUTATED | 32 | 59 | 6 |
| 10Q LOSS WILD-TYPE | 195 | 52 | 169 |
Figure S331. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S332. Gene #60: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 10Q LOSS MUTATED | 11 | 74 | 6 | 6 |
| 10Q LOSS WILD-TYPE | 198 | 60 | 151 | 7 |
Figure S332. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00907 (Fisher's exact test), Q value = 0.027
Table S333. Gene #60: '10q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 10Q LOSS MUTATED | 12 | 28 | 17 | 17 |
| 10Q LOSS WILD-TYPE | 79 | 67 | 108 | 98 |
Figure S333. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00061
Table S334. Gene #60: '10q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 10Q LOSS MUTATED | 6 | 20 | 48 |
| 10Q LOSS WILD-TYPE | 77 | 138 | 137 |
Figure S334. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S335. Gene #60: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 10Q LOSS MUTATED | 5 | 71 | 1 | 16 | 4 |
| 10Q LOSS WILD-TYPE | 125 | 44 | 104 | 117 | 26 |
Figure S335. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S336. Gene #60: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 10Q LOSS MUTATED | 6 | 60 | 3 | 14 | 3 | 10 | 1 |
| 10Q LOSS WILD-TYPE | 129 | 11 | 33 | 54 | 87 | 31 | 71 |
Figure S336. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00042
Table S337. Gene #60: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 10Q LOSS MUTATED | 35 | 32 | 6 | 24 |
| 10Q LOSS WILD-TYPE | 105 | 75 | 76 | 156 |
Figure S337. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S338. Gene #60: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 10Q LOSS MUTATED | 15 | 15 | 67 |
| 10Q LOSS WILD-TYPE | 207 | 169 | 36 |
Figure S338. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S339. Gene #60: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 10Q LOSS MUTATED | 31 | 42 | 5 | 19 |
| 10Q LOSS WILD-TYPE | 96 | 77 | 100 | 135 |
Figure S339. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S340. Gene #60: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 10Q LOSS MUTATED | 8 | 9 | 12 | 1 | 56 | 11 |
| 10Q LOSS WILD-TYPE | 91 | 68 | 106 | 55 | 7 | 81 |
Figure S340. Get High-res Image Gene #60: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0311 (Fisher's exact test), Q value = 0.073
Table S341. Gene #61: '11p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 11P LOSS MUTATED | 1 | 4 | 0 | 0 |
| 11P LOSS WILD-TYPE | 6 | 3 | 7 | 6 |
Figure S341. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S342. Gene #61: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 11P LOSS MUTATED | 46 | 17 | 0 |
| 11P LOSS WILD-TYPE | 181 | 94 | 175 |
Figure S342. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S343. Gene #61: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 11P LOSS MUTATED | 38 | 17 | 0 | 8 |
| 11P LOSS WILD-TYPE | 171 | 117 | 157 | 5 |
Figure S343. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0114 (Fisher's exact test), Q value = 0.033
Table S344. Gene #61: '11p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 11P LOSS MUTATED | 14 | 18 | 8 | 9 |
| 11P LOSS WILD-TYPE | 77 | 77 | 117 | 106 |
Figure S344. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S345. Gene #61: '11p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 11P LOSS MUTATED | 13 | 31 | 0 | 12 | 7 |
| 11P LOSS WILD-TYPE | 117 | 84 | 105 | 121 | 23 |
Figure S345. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S346. Gene #61: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 11P LOSS MUTATED | 17 | 9 | 0 | 6 | 0 | 25 | 6 |
| 11P LOSS WILD-TYPE | 118 | 62 | 36 | 62 | 90 | 16 | 66 |
Figure S346. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S347. Gene #61: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 11P LOSS MUTATED | 13 | 29 | 4 | 17 |
| 11P LOSS WILD-TYPE | 127 | 78 | 78 | 163 |
Figure S347. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S348. Gene #61: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 11P LOSS MUTATED | 22 | 14 | 27 |
| 11P LOSS WILD-TYPE | 200 | 170 | 76 |
Figure S348. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00092 (Fisher's exact test), Q value = 0.0042
Table S349. Gene #61: '11p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 11P LOSS MUTATED | 19 | 24 | 4 | 15 |
| 11P LOSS WILD-TYPE | 108 | 95 | 101 | 139 |
Figure S349. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S350. Gene #61: '11p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 11P LOSS MUTATED | 10 | 27 | 10 | 0 | 8 | 7 |
| 11P LOSS WILD-TYPE | 89 | 50 | 108 | 56 | 55 | 85 |
Figure S350. Get High-res Image Gene #61: '11p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S351. Gene #62: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 11Q LOSS MUTATED | 9 | 12 | 0 |
| 11Q LOSS WILD-TYPE | 218 | 99 | 175 |
Figure S351. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0011
Table S352. Gene #62: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 11Q LOSS MUTATED | 7 | 13 | 0 | 1 |
| 11Q LOSS WILD-TYPE | 202 | 121 | 157 | 12 |
Figure S352. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S353. Gene #62: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 11Q LOSS MUTATED | 0 | 16 | 0 | 3 | 2 |
| 11Q LOSS WILD-TYPE | 130 | 99 | 105 | 130 | 28 |
Figure S353. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S354. Gene #62: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 11Q LOSS MUTATED | 2 | 9 | 0 | 2 | 0 | 7 | 1 |
| 11Q LOSS WILD-TYPE | 133 | 62 | 36 | 66 | 90 | 34 | 71 |
Figure S354. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00067
Table S355. Gene #62: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 11Q LOSS MUTATED | 5 | 3 | 13 |
| 11Q LOSS WILD-TYPE | 217 | 181 | 90 |
Figure S355. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00631 (Fisher's exact test), Q value = 0.021
Table S356. Gene #62: '11q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 11Q LOSS MUTATED | 6 | 10 | 0 | 4 |
| 11Q LOSS WILD-TYPE | 121 | 109 | 105 | 150 |
Figure S356. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00138 (Fisher's exact test), Q value = 0.0058
Table S357. Gene #62: '11q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 11Q LOSS MUTATED | 1 | 6 | 3 | 0 | 8 | 2 |
| 11Q LOSS WILD-TYPE | 98 | 71 | 115 | 56 | 55 | 90 |
Figure S357. Get High-res Image Gene #62: '11q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0149 (Fisher's exact test), Q value = 0.042
Table S358. Gene #63: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 12P LOSS MUTATED | 20 | 3 | 5 |
| 12P LOSS WILD-TYPE | 207 | 108 | 170 |
Figure S358. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0016
Table S359. Gene #63: '12p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 12P LOSS MUTATED | 14 | 4 | 5 | 5 |
| 12P LOSS WILD-TYPE | 195 | 130 | 152 | 8 |
Figure S359. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00507 (Fisher's exact test), Q value = 0.017
Table S360. Gene #63: '12p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 12P LOSS MUTATED | 10 | 1 | 1 | 1 | 3 | 8 | 4 |
| 12P LOSS WILD-TYPE | 125 | 70 | 35 | 67 | 87 | 33 | 68 |
Figure S360. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0428 (Fisher's exact test), Q value = 0.095
Table S361. Gene #63: '12p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 12P LOSS MUTATED | 4 | 12 | 3 | 9 |
| 12P LOSS WILD-TYPE | 136 | 95 | 79 | 171 |
Figure S361. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0477 (Fisher's exact test), Q value = 0.1
Table S362. Gene #63: '12p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 12P LOSS MUTATED | 6 | 9 | 7 | 1 | 0 | 5 |
| 12P LOSS WILD-TYPE | 93 | 68 | 111 | 55 | 63 | 87 |
Figure S362. Get High-res Image Gene #63: '12p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S363. Gene #64: '12q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 12Q LOSS MUTATED | 40 | 6 | 6 |
| 12Q LOSS WILD-TYPE | 187 | 105 | 169 |
Figure S363. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S364. Gene #64: '12q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 12Q LOSS MUTATED | 33 | 8 | 5 | 6 |
| 12Q LOSS WILD-TYPE | 176 | 126 | 152 | 7 |
Figure S364. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00089 (Fisher's exact test), Q value = 0.0041
Table S365. Gene #64: '12q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 12Q LOSS MUTATED | 17 | 15 | 1 | 14 | 5 |
| 12Q LOSS WILD-TYPE | 113 | 100 | 104 | 119 | 25 |
Figure S365. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S366. Gene #64: '12q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 12Q LOSS MUTATED | 21 | 1 | 1 | 6 | 3 | 14 | 6 |
| 12Q LOSS WILD-TYPE | 114 | 70 | 35 | 62 | 87 | 27 | 66 |
Figure S366. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00306 (Fisher's exact test), Q value = 0.011
Table S367. Gene #64: '12q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 12Q LOSS MUTATED | 10 | 22 | 5 | 15 |
| 12Q LOSS WILD-TYPE | 130 | 85 | 77 | 165 |
Figure S367. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S368. Gene #64: '12q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 12Q LOSS MUTATED | 13 | 18 | 11 | 1 | 0 | 9 |
| 12Q LOSS WILD-TYPE | 86 | 59 | 107 | 55 | 63 | 83 |
Figure S368. Get High-res Image Gene #64: '12q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S369. Gene #65: '13q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 13Q LOSS MUTATED | 2 | 7 | 0 | 0 |
| 13Q LOSS WILD-TYPE | 5 | 0 | 7 | 6 |
Figure S369. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S370. Gene #65: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 13Q LOSS MUTATED | 42 | 46 | 27 |
| 13Q LOSS WILD-TYPE | 185 | 65 | 148 |
Figure S370. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0433 (Fisher's exact test), Q value = 0.095
Table S371. Gene #65: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 13Q LOSS MUTATED | 52 | 31 | 26 | 6 |
| 13Q LOSS WILD-TYPE | 157 | 103 | 131 | 7 |
Figure S371. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0128 (Fisher's exact test), Q value = 0.037
Table S372. Gene #65: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 13Q LOSS MUTATED | 13 | 32 | 24 | 25 |
| 13Q LOSS WILD-TYPE | 78 | 63 | 101 | 90 |
Figure S372. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0181 (Fisher's exact test), Q value = 0.048
Table S373. Gene #65: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 13Q LOSS MUTATED | 31 | 38 | 16 | 25 | 5 |
| 13Q LOSS WILD-TYPE | 99 | 77 | 89 | 108 | 25 |
Figure S373. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00117 (Fisher's exact test), Q value = 0.0051
Table S374. Gene #65: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 13Q LOSS MUTATED | 33 | 19 | 2 | 11 | 17 | 19 | 14 |
| 13Q LOSS WILD-TYPE | 102 | 52 | 34 | 57 | 73 | 22 | 58 |
Figure S374. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0206 (Fisher's exact test), Q value = 0.053
Table S375. Gene #65: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 13Q LOSS MUTATED | 53 | 30 | 31 |
| 13Q LOSS WILD-TYPE | 169 | 154 | 72 |
Figure S375. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0447 (Fisher's exact test), Q value = 0.097
Table S376. Gene #65: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 13Q LOSS MUTATED | 17 | 24 | 20 | 9 | 18 | 26 |
| 13Q LOSS WILD-TYPE | 82 | 53 | 98 | 47 | 45 | 66 |
Figure S376. Get High-res Image Gene #65: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S377. Gene #66: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 14Q LOSS MUTATED | 22 | 38 | 21 |
| 14Q LOSS WILD-TYPE | 205 | 73 | 154 |
Figure S377. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00178 (Fisher's exact test), Q value = 0.0072
Table S378. Gene #66: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 14Q LOSS MUTATED | 24 | 32 | 20 | 5 |
| 14Q LOSS WILD-TYPE | 185 | 102 | 137 | 8 |
Figure S378. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S379. Gene #66: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 14Q LOSS MUTATED | 10 | 36 | 11 | 17 | 7 |
| 14Q LOSS WILD-TYPE | 120 | 79 | 94 | 116 | 23 |
Figure S379. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.0011
Table S380. Gene #66: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 14Q LOSS MUTATED | 16 | 25 | 6 | 9 | 8 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 119 | 46 | 30 | 59 | 82 | 31 | 65 |
Figure S380. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0191 (Fisher's exact test), Q value = 0.05
Table S381. Gene #66: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 14Q LOSS MUTATED | 34 | 13 | 11 | 22 |
| 14Q LOSS WILD-TYPE | 106 | 94 | 71 | 158 |
Figure S381. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00126 (Fisher's exact test), Q value = 0.0054
Table S382. Gene #66: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 14Q LOSS MUTATED | 28 | 23 | 29 |
| 14Q LOSS WILD-TYPE | 194 | 161 | 74 |
Figure S382. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0123 (Fisher's exact test), Q value = 0.036
Table S383. Gene #66: '14q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 14Q LOSS MUTATED | 22 | 29 | 10 | 19 |
| 14Q LOSS WILD-TYPE | 105 | 90 | 95 | 135 |
Figure S383. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00149 (Fisher's exact test), Q value = 0.0062
Table S384. Gene #66: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 14Q LOSS MUTATED | 14 | 16 | 15 | 6 | 21 | 8 |
| 14Q LOSS WILD-TYPE | 85 | 61 | 103 | 50 | 42 | 84 |
Figure S384. Get High-res Image Gene #66: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0159 (Fisher's exact test), Q value = 0.043
Table S385. Gene #67: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 15Q LOSS MUTATED | 14 | 11 | 26 |
| 15Q LOSS WILD-TYPE | 213 | 100 | 149 |
Figure S385. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S386. Gene #67: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 15Q LOSS MUTATED | 13 | 5 | 28 | 5 |
| 15Q LOSS WILD-TYPE | 196 | 129 | 129 | 8 |
Figure S386. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0145 (Fisher's exact test), Q value = 0.041
Table S387. Gene #67: '15q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 15Q LOSS MUTATED | 6 | 16 | 14 | 5 |
| 15Q LOSS WILD-TYPE | 85 | 79 | 111 | 110 |
Figure S387. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00276 (Fisher's exact test), Q value = 0.01
Table S388. Gene #67: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 15Q LOSS MUTATED | 5 | 13 | 20 | 10 | 3 |
| 15Q LOSS WILD-TYPE | 125 | 102 | 85 | 123 | 27 |
Figure S388. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S389. Gene #67: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 15Q LOSS MUTATED | 7 | 2 | 6 | 2 | 18 | 10 | 6 |
| 15Q LOSS WILD-TYPE | 128 | 69 | 30 | 66 | 72 | 31 | 66 |
Figure S389. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00053 (Fisher's exact test), Q value = 0.0027
Table S390. Gene #67: '15q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 15Q LOSS MUTATED | 7 | 13 | 7 | 14 | 2 | 8 |
| 15Q LOSS WILD-TYPE | 92 | 64 | 111 | 42 | 61 | 84 |
Figure S390. Get High-res Image Gene #67: '15q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0304 (Fisher's exact test), Q value = 0.072
Table S391. Gene #68: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 16P LOSS MUTATED | 7 | 6 | 1 |
| 16P LOSS WILD-TYPE | 220 | 105 | 174 |
Figure S391. Get High-res Image Gene #68: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0375 (Fisher's exact test), Q value = 0.085
Table S392. Gene #68: '16p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 16P LOSS MUTATED | 1 | 8 | 1 | 4 | 0 |
| 16P LOSS WILD-TYPE | 129 | 107 | 104 | 129 | 30 |
Figure S392. Get High-res Image Gene #68: '16p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0227 (Fisher's exact test), Q value = 0.058
Table S393. Gene #68: '16p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 16P LOSS MUTATED | 1 | 4 | 0 | 5 | 2 | 2 | 0 |
| 16P LOSS WILD-TYPE | 134 | 67 | 36 | 63 | 88 | 39 | 72 |
Figure S393. Get High-res Image Gene #68: '16p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0056 (Fisher's exact test), Q value = 0.019
Table S394. Gene #69: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 16Q LOSS MUTATED | 10 | 10 | 2 |
| 16Q LOSS WILD-TYPE | 217 | 101 | 173 |
Figure S394. Get High-res Image Gene #69: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00567 (Fisher's exact test), Q value = 0.019
Table S395. Gene #69: '16q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 16Q LOSS MUTATED | 0 | 3 | 13 |
| 16Q LOSS WILD-TYPE | 83 | 155 | 172 |
Figure S395. Get High-res Image Gene #69: '16q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0211 (Fisher's exact test), Q value = 0.054
Table S396. Gene #69: '16q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 16Q LOSS MUTATED | 4 | 12 | 2 | 4 | 0 |
| 16Q LOSS WILD-TYPE | 126 | 103 | 103 | 129 | 30 |
Figure S396. Get High-res Image Gene #69: '16q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0206 (Fisher's exact test), Q value = 0.053
Table S397. Gene #69: '16q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 16Q LOSS MUTATED | 4 | 8 | 1 | 5 | 2 | 2 | 0 |
| 16Q LOSS WILD-TYPE | 131 | 63 | 35 | 63 | 88 | 39 | 72 |
Figure S397. Get High-res Image Gene #69: '16q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00376 (Fisher's exact test), Q value = 0.014
Table S398. Gene #69: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 16Q LOSS MUTATED | 7 | 4 | 11 |
| 16Q LOSS WILD-TYPE | 215 | 180 | 92 |
Figure S398. Get High-res Image Gene #69: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00094 (Fisher's exact test), Q value = 0.0042
Table S399. Gene #70: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 17P LOSS MUTATED | 4 | 9 | 1 |
| 17P LOSS WILD-TYPE | 223 | 102 | 174 |
Figure S399. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0101 (Fisher's exact test), Q value = 0.03
Table S400. Gene #70: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 17P LOSS MUTATED | 3 | 7 | 2 | 2 |
| 17P LOSS WILD-TYPE | 206 | 127 | 155 | 11 |
Figure S400. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00049 (Fisher's exact test), Q value = 0.0025
Table S401. Gene #70: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 17P LOSS MUTATED | 0 | 9 | 2 | 1 | 2 |
| 17P LOSS WILD-TYPE | 130 | 106 | 103 | 132 | 28 |
Figure S401. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00214 (Fisher's exact test), Q value = 0.0085
Table S402. Gene #70: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 17P LOSS MUTATED | 5 | 1 | 8 |
| 17P LOSS WILD-TYPE | 217 | 183 | 95 |
Figure S402. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0452 (Fisher's exact test), Q value = 0.098
Table S403. Gene #70: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 17P LOSS MUTATED | 3 | 2 | 0 | 1 | 5 | 2 |
| 17P LOSS WILD-TYPE | 96 | 75 | 118 | 55 | 58 | 90 |
Figure S403. Get High-res Image Gene #70: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00291 (Fisher's exact test), Q value = 0.011
Table S404. Gene #71: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 17Q LOSS MUTATED | 3 | 6 | 0 |
| 17Q LOSS WILD-TYPE | 224 | 105 | 175 |
Figure S404. Get High-res Image Gene #71: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0109 (Fisher's exact test), Q value = 0.032
Table S405. Gene #71: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 17Q LOSS MUTATED | 0 | 5 | 1 | 1 | 2 |
| 17Q LOSS WILD-TYPE | 130 | 110 | 104 | 132 | 28 |
Figure S405. Get High-res Image Gene #71: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0302 (Fisher's exact test), Q value = 0.072
Table S406. Gene #72: '18p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 18P LOSS MUTATED | 0 | 4 | 1 | 0 |
| 18P LOSS WILD-TYPE | 7 | 3 | 6 | 6 |
Figure S406. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00749 (Fisher's exact test), Q value = 0.023
Table S407. Gene #72: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 18P LOSS MUTATED | 18 | 19 | 30 |
| 18P LOSS WILD-TYPE | 209 | 92 | 145 |
Figure S407. Get High-res Image Gene #72: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00091 (Fisher's exact test), Q value = 0.0042
Table S408. Gene #73: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 18Q LOSS MUTATED | 15 | 14 | 33 |
| 18Q LOSS WILD-TYPE | 212 | 97 | 142 |
Figure S408. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00091 (Fisher's exact test), Q value = 0.0042
Table S409. Gene #73: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 18Q LOSS MUTATED | 19 | 10 | 33 | 0 |
| 18Q LOSS WILD-TYPE | 190 | 124 | 124 | 13 |
Figure S409. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0154 (Fisher's exact test), Q value = 0.043
Table S410. Gene #73: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 18Q LOSS MUTATED | 9 | 8 | 7 | 6 | 20 | 6 | 6 |
| 18Q LOSS WILD-TYPE | 126 | 63 | 29 | 62 | 70 | 35 | 66 |
Figure S410. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0181 (Fisher's exact test), Q value = 0.048
Table S411. Gene #73: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 18Q LOSS MUTATED | 17 | 7 | 18 | 20 |
| 18Q LOSS WILD-TYPE | 123 | 100 | 64 | 160 |
Figure S411. Get High-res Image Gene #73: '18q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0411 (Fisher's exact test), Q value = 0.092
Table S412. Gene #74: '19p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 19P LOSS MUTATED | 3 | 9 | 9 | 4 |
| 19P LOSS WILD-TYPE | 124 | 110 | 96 | 150 |
Figure S412. Get High-res Image Gene #74: '19p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0133 (Fisher's exact test), Q value = 0.038
Table S413. Gene #75: '19q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 19Q LOSS MUTATED | 1 | 6 | 6 | 2 |
| 19Q LOSS WILD-TYPE | 6 | 1 | 1 | 4 |
Figure S413. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S414. Gene #75: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 19Q LOSS MUTATED | 22 | 22 | 165 |
| 19Q LOSS WILD-TYPE | 205 | 89 | 10 |
Figure S414. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S415. Gene #75: '19q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 19Q LOSS MUTATED | 28 | 24 | 156 | 1 |
| 19Q LOSS WILD-TYPE | 181 | 110 | 1 | 12 |
Figure S415. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00821 (Fisher's exact test), Q value = 0.025
Table S416. Gene #75: '19q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 19Q LOSS MUTATED | 28 | 82 | 71 |
| 19Q LOSS WILD-TYPE | 55 | 76 | 114 |
Figure S416. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S417. Gene #75: '19q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 19Q LOSS MUTATED | 16 | 16 | 103 | 63 | 11 |
| 19Q LOSS WILD-TYPE | 114 | 99 | 2 | 70 | 19 |
Figure S417. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S418. Gene #75: '19q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 19Q LOSS MUTATED | 16 | 5 | 36 | 8 | 87 | 8 | 49 |
| 19Q LOSS WILD-TYPE | 119 | 66 | 0 | 60 | 3 | 33 | 23 |
Figure S418. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S419. Gene #75: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| 19Q LOSS MUTATED | 33 | 20 | 70 | 86 |
| 19Q LOSS WILD-TYPE | 107 | 87 | 12 | 94 |
Figure S419. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S420. Gene #75: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 19Q LOSS MUTATED | 97 | 103 | 9 |
| 19Q LOSS WILD-TYPE | 125 | 81 | 94 |
Figure S420. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S421. Gene #75: '19q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 19Q LOSS MUTATED | 22 | 26 | 87 | 73 |
| 19Q LOSS WILD-TYPE | 105 | 93 | 18 | 81 |
Figure S421. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S422. Gene #75: '19q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 19Q LOSS MUTATED | 11 | 38 | 62 | 55 | 2 | 40 |
| 19Q LOSS WILD-TYPE | 88 | 39 | 56 | 1 | 61 | 52 |
Figure S422. Get High-res Image Gene #75: '19q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0151 (Fisher's exact test), Q value = 0.042
Table S423. Gene #76: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 20P LOSS MUTATED | 7 | 0 | 0 |
| 20P LOSS WILD-TYPE | 220 | 111 | 175 |
Figure S423. Get High-res Image Gene #76: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0369 (Fisher's exact test), Q value = 0.084
Table S424. Gene #76: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 20P LOSS MUTATED | 5 | 1 | 0 | 1 |
| 20P LOSS WILD-TYPE | 204 | 133 | 157 | 12 |
Figure S424. Get High-res Image Gene #76: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.039 (Fisher's exact test), Q value = 0.088
Table S425. Gene #77: '20q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 20Q LOSS MUTATED | 2 | 0 | 0 | 1 |
| 20Q LOSS WILD-TYPE | 207 | 134 | 157 | 12 |
Figure S425. Get High-res Image Gene #77: '20q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0345 (Fisher's exact test), Q value = 0.08
Table S426. Gene #77: '20q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 20Q LOSS MUTATED | 0 | 2 | 0 | 0 | 1 |
| 20Q LOSS WILD-TYPE | 130 | 113 | 105 | 133 | 29 |
Figure S426. Get High-res Image Gene #77: '20q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00692 (Fisher's exact test), Q value = 0.022
Table S427. Gene #78: '21q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 21Q LOSS MUTATED | 0 | 4 | 0 | 0 |
| 21Q LOSS WILD-TYPE | 7 | 3 | 7 | 6 |
Figure S427. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00082
Table S428. Gene #78: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 21Q LOSS MUTATED | 19 | 16 | 3 |
| 21Q LOSS WILD-TYPE | 208 | 95 | 172 |
Figure S428. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00036
Table S429. Gene #78: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 21Q LOSS MUTATED | 23 | 9 | 2 | 4 |
| 21Q LOSS WILD-TYPE | 186 | 125 | 155 | 9 |
Figure S429. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00129 (Fisher's exact test), Q value = 0.0055
Table S430. Gene #78: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 21Q LOSS MUTATED | 13 | 13 | 1 | 6 | 5 |
| 21Q LOSS WILD-TYPE | 117 | 102 | 104 | 127 | 25 |
Figure S430. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S431. Gene #78: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 21Q LOSS MUTATED | 16 | 3 | 2 | 4 | 0 | 11 | 2 |
| 21Q LOSS WILD-TYPE | 119 | 68 | 34 | 64 | 90 | 30 | 70 |
Figure S431. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0486 (Fisher's exact test), Q value = 0.1
Table S432. Gene #78: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 21Q LOSS MUTATED | 21 | 7 | 10 |
| 21Q LOSS WILD-TYPE | 201 | 177 | 93 |
Figure S432. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0254 (Fisher's exact test), Q value = 0.063
Table S433. Gene #78: '21q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 21Q LOSS MUTATED | 10 | 12 | 5 | 1 | 3 | 6 |
| 21Q LOSS WILD-TYPE | 89 | 65 | 113 | 55 | 60 | 86 |
Figure S433. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00658 (Fisher's exact test), Q value = 0.021
Table S434. Gene #79: '22q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 7 | 7 | 7 | 6 |
| 22Q LOSS MUTATED | 0 | 4 | 0 | 0 |
| 22Q LOSS WILD-TYPE | 7 | 3 | 7 | 6 |
Figure S434. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S435. Gene #79: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| 22Q LOSS MUTATED | 21 | 32 | 4 |
| 22Q LOSS WILD-TYPE | 206 | 79 | 171 |
Figure S435. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S436. Gene #79: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| 22Q LOSS MUTATED | 22 | 28 | 4 | 3 |
| 22Q LOSS WILD-TYPE | 187 | 106 | 153 | 10 |
Figure S436. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0019
Table S437. Gene #79: '22q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| 22Q LOSS MUTATED | 5 | 23 | 10 | 10 |
| 22Q LOSS WILD-TYPE | 86 | 72 | 115 | 105 |
Figure S437. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0389 (Fisher's exact test), Q value = 0.088
Table S438. Gene #79: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| 22Q LOSS MUTATED | 5 | 14 | 29 |
| 22Q LOSS WILD-TYPE | 78 | 144 | 156 |
Figure S438. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S439. Gene #79: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| 22Q LOSS MUTATED | 8 | 31 | 2 | 11 | 5 |
| 22Q LOSS WILD-TYPE | 122 | 84 | 103 | 122 | 25 |
Figure S439. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S440. Gene #79: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| 22Q LOSS MUTATED | 11 | 21 | 2 | 11 | 2 | 9 | 1 |
| 22Q LOSS WILD-TYPE | 124 | 50 | 34 | 57 | 88 | 32 | 71 |
Figure S440. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-04 (Fisher's exact test), Q value = 0.0016
Table S441. Gene #79: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 22Q LOSS MUTATED | 18 | 15 | 24 |
| 22Q LOSS WILD-TYPE | 204 | 169 | 79 |
Figure S441. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00165 (Fisher's exact test), Q value = 0.0068
Table S442. Gene #79: '22q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| 22Q LOSS MUTATED | 17 | 23 | 5 | 11 |
| 22Q LOSS WILD-TYPE | 110 | 96 | 100 | 143 |
Figure S442. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00016
Table S443. Gene #79: '22q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| 22Q LOSS MUTATED | 3 | 15 | 10 | 3 | 17 | 8 |
| 22Q LOSS WILD-TYPE | 96 | 62 | 108 | 53 | 46 | 84 |
Figure S443. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00286 (Fisher's exact test), Q value = 0.011
Table S444. Gene #80: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| XP LOSS MUTATED | 44 | 16 | 32 | 7 |
| XP LOSS WILD-TYPE | 165 | 118 | 125 | 6 |
Figure S444. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00246 (Fisher's exact test), Q value = 0.0095
Table S445. Gene #80: 'xp loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| XP LOSS MUTATED | 10 | 30 | 29 | 18 |
| XP LOSS WILD-TYPE | 81 | 65 | 96 | 97 |
Figure S445. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00588 (Fisher's exact test), Q value = 0.02
Table S446. Gene #80: 'xp loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| XP LOSS MUTATED | 11 | 25 | 51 |
| XP LOSS WILD-TYPE | 72 | 133 | 134 |
Figure S446. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S447. Gene #80: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| XP LOSS MUTATED | 29 | 10 | 10 | 9 | 20 | 18 | 3 |
| XP LOSS WILD-TYPE | 106 | 61 | 26 | 59 | 70 | 23 | 69 |
Figure S447. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0238 (Fisher's exact test), Q value = 0.06
Table S448. Gene #80: 'xp loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| XP LOSS MUTATED | 22 | 24 | 25 | 28 |
| XP LOSS WILD-TYPE | 118 | 83 | 57 | 152 |
Figure S448. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00107 (Fisher's exact test), Q value = 0.0047
Table S449. Gene #80: 'xp loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| XP LOSS MUTATED | 33 | 19 | 29 | 17 |
| XP LOSS WILD-TYPE | 94 | 100 | 76 | 137 |
Figure S449. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00033 (Fisher's exact test), Q value = 0.0018
Table S450. Gene #80: 'xp loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| XP LOSS MUTATED | 20 | 23 | 9 | 13 | 8 | 25 |
| XP LOSS WILD-TYPE | 79 | 54 | 109 | 43 | 55 | 67 |
Figure S450. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0076 (Fisher's exact test), Q value = 0.024
Table S451. Gene #81: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 227 | 111 | 175 |
| XQ LOSS MUTATED | 20 | 16 | 34 |
| XQ LOSS WILD-TYPE | 207 | 95 | 141 |
Figure S451. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0011
Table S452. Gene #81: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 209 | 134 | 157 | 13 |
| XQ LOSS MUTATED | 20 | 12 | 32 | 6 |
| XQ LOSS WILD-TYPE | 189 | 122 | 125 | 7 |
Figure S452. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00048
Table S453. Gene #81: 'xq loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 95 | 125 | 115 |
| XQ LOSS MUTATED | 4 | 27 | 15 | 15 |
| XQ LOSS WILD-TYPE | 87 | 68 | 110 | 100 |
Figure S453. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0167 (Fisher's exact test), Q value = 0.045
Table S454. Gene #81: 'xq loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 83 | 158 | 185 |
| XQ LOSS MUTATED | 5 | 21 | 35 |
| XQ LOSS WILD-TYPE | 78 | 137 | 150 |
Figure S454. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0012
Table S455. Gene #81: 'xq loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 130 | 115 | 105 | 133 | 30 |
| XQ LOSS MUTATED | 10 | 23 | 24 | 13 | 0 |
| XQ LOSS WILD-TYPE | 120 | 92 | 81 | 120 | 30 |
Figure S455. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 8.6e-05
Table S456. Gene #81: 'xq loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 135 | 71 | 36 | 68 | 90 | 41 | 72 |
| XQ LOSS MUTATED | 9 | 9 | 10 | 7 | 20 | 13 | 2 |
| XQ LOSS WILD-TYPE | 126 | 62 | 26 | 61 | 70 | 28 | 70 |
Figure S456. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S457. Gene #81: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 107 | 82 | 180 |
| XQ LOSS MUTATED | 11 | 16 | 26 | 17 |
| XQ LOSS WILD-TYPE | 129 | 91 | 56 | 163 |
Figure S457. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00073
Table S458. Gene #81: 'xq loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 127 | 119 | 105 | 154 |
| XQ LOSS MUTATED | 19 | 11 | 28 | 11 |
| XQ LOSS WILD-TYPE | 108 | 108 | 77 | 143 |
Figure S458. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0033
Table S459. Gene #81: 'xq loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 99 | 77 | 118 | 56 | 63 | 92 |
| XQ LOSS MUTATED | 9 | 17 | 6 | 13 | 7 | 17 |
| XQ LOSS WILD-TYPE | 90 | 60 | 112 | 43 | 56 | 75 |
Figure S459. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
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Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/LGG-TP/22533657/transformed.cor.cli.txt
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Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/LGG-TP/22553887/LGG-TP.transferedmergedcluster.txt
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Number of patients = 513
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Number of significantly arm-level cnvs = 81
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Number of molecular subtypes = 12
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Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.