This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 82 arm-level events and 12 molecular subtypes across 501 patients, 434 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF'.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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4p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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4q gain cnv correlated to 'CN_CNMF'.
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5p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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5q gain cnv correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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6q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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7p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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7q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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8q gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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9p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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9q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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10p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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11p gain cnv correlated to 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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13q gain cnv correlated to 'CN_CNMF'.
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14q gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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15q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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16p gain cnv correlated to 'CN_CNMF'.
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16q gain cnv correlated to 'CN_CNMF'.
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17p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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17q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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19p gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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19q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'METHLYATION_CNMF'.
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20q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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22q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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xp gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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xq gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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1p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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2p loss cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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2q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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3p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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4p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'RPPA_CHIERARCHICAL'.
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5q loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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6p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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6q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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7p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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7q loss cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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8q loss cnv correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_CNMF'.
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9p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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10q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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11p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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11q loss cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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12p loss cnv correlated to 'MRNA_CNMF' and 'MRNA_CHIERARCHICAL'.
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12q loss cnv correlated to 'MIRSEQ_CNMF'.
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13q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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14q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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16p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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16q loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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18p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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18q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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19p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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19q loss cnv correlated to 'CN_CNMF'.
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20p loss cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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20q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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21q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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22q loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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xp loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xq loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 82 arm-level events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 434 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 4p loss | 315 (63%) | 186 |
0.00049 (0.00319) |
5e-05 (0.000518) |
1e-05 (0.000135) |
2e-05 (0.000232) |
0.00471 (0.0193) |
0.0266 (0.0727) |
1e-05 (0.000135) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.0492 (0.112) |
6e-05 (0.000602) |
8e-05 (0.000779) |
| 9q loss | 247 (49%) | 254 |
2e-05 (0.000232) |
1e-05 (0.000135) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.00071 (0.00421) |
0.00169 (0.0088) |
1e-05 (0.000135) |
1e-05 (0.000135) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.00264 (0.0122) |
0.0011 (0.00595) |
| 7q gain | 220 (44%) | 281 |
0.00379 (0.0164) |
0.00032 (0.00235) |
1e-05 (0.000135) |
0.00018 (0.00146) |
0.0323 (0.0825) |
0.624 (0.72) |
1e-05 (0.000135) |
1e-05 (0.000135) |
9e-05 (0.000868) |
0.00089 (0.005) |
0.0146 (0.0468) |
0.0178 (0.0538) |
| 12p gain | 226 (45%) | 275 |
0.0146 (0.0468) |
0.0254 (0.0702) |
1e-05 (0.000135) |
0.00442 (0.0187) |
0.0386 (0.0933) |
0.624 (0.72) |
1e-05 (0.000135) |
0.00197 (0.00979) |
0.0118 (0.0395) |
0.0053 (0.0212) |
0.00066 (0.00398) |
0.0133 (0.0437) |
| 17q gain | 158 (32%) | 343 |
0.00021 (0.00161) |
0.00102 (0.00555) |
1e-05 (0.000135) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.207 (0.315) |
1e-05 (0.000135) |
1e-05 (0.000135) |
2e-05 (0.000232) |
0.00769 (0.0282) |
0.00011 (0.00101) |
0.00037 (0.00264) |
| 1p loss | 155 (31%) | 346 |
1e-05 (0.000135) |
1e-05 (0.000135) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.0219 (0.064) |
0.348 (0.465) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.00014 (0.00121) |
1e-05 (0.000135) |
0.00017 (0.00139) |
0.00558 (0.022) |
| 2p gain | 223 (45%) | 278 |
0.142 (0.245) |
0.017 (0.0518) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.0168 (0.0514) |
0.125 (0.227) |
1e-05 (0.000135) |
2e-05 (0.000232) |
0.00289 (0.0131) |
0.0315 (0.0809) |
0.00169 (0.0088) |
0.00291 (0.0131) |
| 9q gain | 91 (18%) | 410 |
0.0294 (0.0763) |
0.00175 (0.00897) |
1e-05 (0.000135) |
1e-05 (0.000135) |
4e-05 (0.000423) |
0.00317 (0.0141) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.00013 (0.00115) |
8e-05 (0.000779) |
0.304 (0.421) |
0.0947 (0.186) |
| 9p loss | 315 (63%) | 186 |
0.0237 (0.0672) |
0.0026 (0.0122) |
1e-05 (0.000135) |
0.00172 (0.00891) |
0.186 (0.293) |
0.0978 (0.19) |
1e-05 (0.000135) |
3e-05 (0.000324) |
0.00807 (0.0292) |
0.00046 (0.0031) |
2e-05 (0.000232) |
0.0155 (0.0485) |
| 10q loss | 229 (46%) | 272 |
0.00464 (0.0192) |
0.00021 (0.00161) |
1e-05 (0.000135) |
8e-05 (0.000779) |
0.00687 (0.0261) |
0.175 (0.282) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.0005 (0.00324) |
1e-05 (0.000135) |
0.00046 (0.0031) |
0.117 (0.215) |
| 14q loss | 167 (33%) | 334 |
1e-05 (0.000135) |
0.0002 (0.00159) |
1e-05 (0.000135) |
0.0399 (0.0954) |
0.00291 (0.0131) |
0.143 (0.245) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.00028 (0.0021) |
1e-05 (0.000135) |
0.0824 (0.167) |
0.00067 (0.00402) |
| 18p gain | 148 (30%) | 353 |
0.0147 (0.0468) |
0.00066 (0.00398) |
1e-05 (0.000135) |
3e-05 (0.000324) |
0.106 (0.202) |
0.0195 (0.0584) |
0.00093 (0.00514) |
1e-05 (0.000135) |
0.0133 (0.0437) |
0.28 (0.399) |
0.181 (0.287) |
0.0474 (0.108) |
| 4q loss | 297 (59%) | 204 |
0.00176 (0.00897) |
0.00256 (0.0121) |
1e-05 (0.000135) |
0.00066 (0.00398) |
0.141 (0.245) |
0.157 (0.263) |
1e-05 (0.000135) |
0.00039 (0.00272) |
1e-05 (0.000135) |
0.0504 (0.113) |
0.00066 (0.00398) |
0.00815 (0.0294) |
| 17p loss | 292 (58%) | 209 |
0.0202 (0.0596) |
0.171 (0.279) |
6e-05 (0.000602) |
0.0114 (0.0386) |
0.656 (0.743) |
0.0327 (0.083) |
0.00404 (0.0173) |
0.00098 (0.00536) |
0.00591 (0.023) |
0.00243 (0.0116) |
0.0574 (0.126) |
0.0368 (0.0899) |
| 1q gain | 202 (40%) | 299 |
0.787 (0.84) |
0.668 (0.752) |
0.0001 (0.000955) |
0.00662 (0.0253) |
0.0807 (0.165) |
0.984 (0.988) |
0.00752 (0.0278) |
0.00053 (0.00334) |
0.00026 (0.00197) |
0.00304 (0.0136) |
0.0221 (0.0642) |
0.0204 (0.06) |
| 7p gain | 238 (48%) | 263 |
0.0695 (0.148) |
0.0104 (0.0356) |
1e-05 (0.000135) |
0.00289 (0.0131) |
0.136 (0.238) |
0.693 (0.77) |
3e-05 (0.000324) |
1e-05 (0.000135) |
0.00222 (0.0107) |
0.00063 (0.0039) |
0.0197 (0.0585) |
0.319 (0.436) |
| 9p gain | 62 (12%) | 439 |
0.121 (0.221) |
0.0272 (0.0737) |
2e-05 (0.000232) |
0.0009 (0.00503) |
0.106 (0.202) |
0.0294 (0.0763) |
3e-05 (0.000324) |
1e-05 (0.000135) |
0.0784 (0.162) |
0.0328 (0.0831) |
0.0405 (0.0962) |
0.166 (0.272) |
| 12q gain | 151 (30%) | 350 |
0.0776 (0.16) |
0.494 (0.604) |
5e-05 (0.000518) |
0.00136 (0.00727) |
0.0441 (0.103) |
0.356 (0.47) |
0.00751 (0.0278) |
0.00285 (0.013) |
0.0155 (0.0486) |
0.176 (0.283) |
0.0294 (0.0763) |
0.00073 (0.00425) |
| 17p gain | 65 (13%) | 436 |
0.00511 (0.0207) |
0.0396 (0.0948) |
0.00015 (0.00127) |
0.0047 (0.0193) |
0.0123 (0.041) |
0.224 (0.337) |
0.00037 (0.00264) |
0.00061 (0.0038) |
0.00262 (0.0122) |
0.129 (0.232) |
0.106 (0.202) |
0.157 (0.263) |
| 19p gain | 115 (23%) | 386 |
0.0253 (0.0702) |
0.15 (0.254) |
1e-05 (0.000135) |
0.00575 (0.0225) |
0.017 (0.0518) |
0.321 (0.437) |
0.00014 (0.00121) |
0.00386 (0.0166) |
0.00626 (0.0241) |
0.00194 (0.00969) |
0.0763 (0.158) |
0.0887 (0.177) |
| 5q loss | 290 (58%) | 211 |
0.153 (0.259) |
0.0375 (0.0912) |
2e-05 (0.000232) |
0.0045 (0.0188) |
0.224 (0.337) |
0.289 (0.408) |
0.00985 (0.0344) |
0.0008 (0.0046) |
0.0309 (0.0797) |
0.0444 (0.103) |
0.00356 (0.0155) |
0.182 (0.288) |
| 6p loss | 114 (23%) | 387 |
0.028 (0.0748) |
0.00732 (0.0275) |
0.00073 (0.00425) |
0.00051 (0.00326) |
0.797 (0.848) |
0.495 (0.605) |
2e-05 (0.000232) |
1e-05 (0.000135) |
0.304 (0.421) |
0.0391 (0.094) |
0.0317 (0.0814) |
0.683 (0.764) |
| 10p loss | 215 (43%) | 286 |
0.398 (0.511) |
0.262 (0.379) |
1e-05 (0.000135) |
0.00021 (0.00161) |
0.00749 (0.0278) |
0.138 (0.24) |
2e-05 (0.000232) |
0.00014 (0.00121) |
0.00011 (0.00101) |
1e-05 (0.000135) |
0.00336 (0.0148) |
0.156 (0.263) |
| 17q loss | 91 (18%) | 410 |
0.0135 (0.0443) |
0.00608 (0.0236) |
0.00024 (0.00183) |
0.00905 (0.0321) |
0.0975 (0.19) |
0.131 (0.234) |
0.00021 (0.00161) |
1e-05 (0.000135) |
0.01 (0.0348) |
0.0073 (0.0275) |
0.181 (0.287) |
0.131 (0.234) |
| xp loss | 145 (29%) | 356 |
0.284 (0.402) |
0.633 (0.722) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.162 (0.27) |
0.364 (0.477) |
0.00174 (0.00896) |
0.0267 (0.0727) |
0.00526 (0.0212) |
0.00157 (0.00831) |
0.00069 (0.00411) |
0.0209 (0.0613) |
| 15q gain | 107 (21%) | 394 |
0.748 (0.805) |
0.427 (0.542) |
1e-05 (0.000135) |
0.00082 (0.00466) |
0.969 (0.981) |
0.663 (0.748) |
0.00139 (0.00739) |
0.0119 (0.04) |
0.0024 (0.0115) |
0.0253 (0.0702) |
0.0198 (0.0586) |
0.0888 (0.177) |
| 16q loss | 184 (37%) | 317 |
0.882 (0.913) |
0.0981 (0.19) |
0.0267 (0.0727) |
0.0684 (0.146) |
0.0022 (0.0107) |
0.0998 (0.193) |
0.0274 (0.074) |
0.0222 (0.0642) |
0.00259 (0.0122) |
0.312 (0.43) |
0.0255 (0.0702) |
0.00531 (0.0212) |
| xq loss | 114 (23%) | 387 |
0.187 (0.294) |
0.353 (0.468) |
1e-05 (0.000135) |
1e-05 (0.000135) |
0.315 (0.432) |
0.363 (0.477) |
0.00722 (0.0273) |
0.981 (0.986) |
0.00011 (0.00101) |
0.012 (0.0401) |
0.00218 (0.0106) |
0.00093 (0.00514) |
| 2q gain | 143 (29%) | 358 |
0.369 (0.482) |
0.147 (0.25) |
3e-05 (0.000324) |
0.26 (0.377) |
0.181 (0.287) |
0.121 (0.221) |
0.00041 (0.00284) |
0.0147 (0.0468) |
0.0284 (0.0757) |
0.28 (0.399) |
0.0178 (0.0538) |
0.0446 (0.103) |
| 8q gain | 256 (51%) | 245 |
0.0961 (0.188) |
0.0264 (0.0725) |
0.00045 (0.00307) |
0.0615 (0.134) |
0.561 (0.663) |
0.625 (0.72) |
0.00198 (0.00979) |
6e-05 (0.000602) |
0.00225 (0.0108) |
0.00194 (0.00969) |
0.49 (0.6) |
0.373 (0.487) |
| 11q gain | 89 (18%) | 412 |
0.00832 (0.0299) |
0.104 (0.2) |
0.0157 (0.0489) |
0.708 (0.777) |
0.626 (0.72) |
0.179 (0.285) |
0.264 (0.383) |
0.0418 (0.0986) |
0.0293 (0.0763) |
0.0502 (0.113) |
0.00051 (0.00326) |
0.0329 (0.0831) |
| 18q gain | 102 (20%) | 399 |
0.0346 (0.0854) |
0.0078 (0.0285) |
2e-05 (0.000232) |
0.00052 (0.0033) |
0.0732 (0.154) |
0.354 (0.469) |
0.00049 (0.00319) |
0.00019 (0.00153) |
0.062 (0.134) |
0.0517 (0.115) |
0.24 (0.356) |
0.216 (0.328) |
| 22q gain | 222 (44%) | 279 |
0.0149 (0.047) |
0.0275 (0.0742) |
1e-05 (0.000135) |
0.0144 (0.0462) |
0.164 (0.271) |
0.143 (0.245) |
0.00096 (0.00528) |
0.00016 (0.00132) |
0.272 (0.391) |
0.0919 (0.182) |
0.614 (0.712) |
0.311 (0.428) |
| 6q loss | 114 (23%) | 387 |
0.00429 (0.0182) |
0.00043 (0.00296) |
0.0384 (0.0931) |
0.0365 (0.0896) |
0.994 (0.995) |
0.498 (0.608) |
0.00038 (0.00267) |
0.00795 (0.029) |
0.599 (0.7) |
0.517 (0.624) |
0.0592 (0.129) |
0.246 (0.36) |
| 21q loss | 264 (53%) | 237 |
0.932 (0.955) |
0.354 (0.469) |
1e-05 (0.000135) |
0.00682 (0.026) |
0.594 (0.695) |
0.39 (0.503) |
0.0339 (0.0849) |
0.0501 (0.113) |
0.00032 (0.00235) |
0.00057 (0.00357) |
0.0173 (0.0526) |
0.127 (0.23) |
| 6q gain | 92 (18%) | 409 |
0.0245 (0.0685) |
0.024 (0.0675) |
0.00016 (0.00132) |
0.117 (0.215) |
0.242 (0.357) |
0.695 (0.77) |
0.00329 (0.0145) |
0.00619 (0.0239) |
0.135 (0.237) |
0.144 (0.246) |
0.683 (0.764) |
0.883 (0.913) |
| 10p gain | 78 (16%) | 423 |
0.367 (0.48) |
0.699 (0.773) |
0.0288 (0.0762) |
0.32 (0.437) |
0.193 (0.299) |
0.189 (0.295) |
0.034 (0.0849) |
0.0389 (0.0939) |
0.115 (0.214) |
0.00078 (0.00451) |
0.482 (0.593) |
0.0422 (0.0993) |
| xq gain | 79 (16%) | 422 |
0.159 (0.266) |
0.0498 (0.113) |
4e-05 (0.000423) |
0.00111 (0.00597) |
0.121 (0.221) |
0.73 (0.794) |
0.0188 (0.0565) |
0.0106 (0.0362) |
0.0658 (0.141) |
0.284 (0.402) |
0.315 (0.432) |
0.661 (0.748) |
| 8p loss | 243 (49%) | 258 |
0.979 (0.986) |
0.937 (0.958) |
0.0131 (0.0434) |
0.0137 (0.0446) |
0.268 (0.387) |
0.472 (0.584) |
0.0517 (0.115) |
0.0799 (0.165) |
0.0333 (0.0838) |
0.024 (0.0675) |
0.00861 (0.0307) |
0.452 (0.564) |
| 16p loss | 163 (33%) | 338 |
0.725 (0.791) |
0.668 (0.752) |
0.00459 (0.0191) |
0.0357 (0.0879) |
0.0218 (0.064) |
0.0557 (0.123) |
0.194 (0.3) |
0.446 (0.559) |
0.015 (0.0472) |
0.726 (0.792) |
0.00206 (0.0101) |
0.0966 (0.189) |
| 19p loss | 162 (32%) | 339 |
0.125 (0.227) |
0.0822 (0.167) |
3e-05 (0.000324) |
0.204 (0.312) |
0.841 (0.883) |
0.699 (0.773) |
0.0346 (0.0854) |
0.0164 (0.0507) |
0.0451 (0.104) |
0.00015 (0.00127) |
0.118 (0.218) |
0.0734 (0.154) |
| 20q loss | 49 (10%) | 452 |
0.047 (0.107) |
0.0755 (0.157) |
0.00049 (0.00319) |
0.0951 (0.186) |
0.252 (0.367) |
0.342 (0.459) |
0.00047 (0.00315) |
0.00764 (0.0282) |
0.00855 (0.0306) |
0.129 (0.232) |
0.387 (0.5) |
0.788 (0.84) |
| 22q loss | 98 (20%) | 403 |
0.0234 (0.067) |
0.101 (0.194) |
0.0018 (0.00908) |
0.284 (0.402) |
0.0719 (0.152) |
0.134 (0.237) |
0.00011 (0.00101) |
1e-05 (0.000135) |
0.359 (0.471) |
0.00914 (0.0324) |
0.349 (0.465) |
0.0548 (0.122) |
| 4p gain | 31 (6%) | 470 |
0.357 (0.47) |
0.1 (0.194) |
0.00036 (0.0026) |
0.0415 (0.0981) |
0.627 (0.72) |
0.154 (0.259) |
0.0197 (0.0585) |
0.00179 (0.00908) |
0.122 (0.223) |
0.325 (0.441) |
0.307 (0.423) |
0.0569 (0.125) |
| 14q gain | 126 (25%) | 375 |
0.133 (0.236) |
0.0237 (0.0672) |
1e-05 (0.000135) |
0.377 (0.49) |
0.379 (0.492) |
0.624 (0.72) |
0.116 (0.215) |
0.00351 (0.0154) |
0.133 (0.236) |
0.116 (0.215) |
0.0429 (0.1) |
0.933 (0.956) |
| 20p gain | 263 (52%) | 238 |
0.00799 (0.029) |
0.00971 (0.034) |
1e-05 (0.000135) |
0.0028 (0.0129) |
0.307 (0.423) |
0.543 (0.647) |
0.0756 (0.157) |
0.091 (0.18) |
0.301 (0.419) |
0.744 (0.802) |
0.277 (0.397) |
0.961 (0.976) |
| xp gain | 64 (13%) | 437 |
0.18 (0.287) |
0.136 (0.238) |
2e-05 (0.000232) |
0.00426 (0.0181) |
0.964 (0.977) |
0.608 (0.708) |
0.01 (0.0348) |
0.217 (0.329) |
0.00265 (0.0122) |
0.244 (0.358) |
0.456 (0.568) |
0.176 (0.283) |
| 2q loss | 44 (9%) | 457 |
0.687 (0.767) |
0.744 (0.802) |
0.0226 (0.0652) |
0.0235 (0.0671) |
0.882 (0.913) |
0.3 (0.419) |
0.224 (0.337) |
0.0817 (0.166) |
0.00462 (0.0192) |
0.145 (0.247) |
0.0166 (0.0512) |
0.164 (0.271) |
| 3p loss | 310 (62%) | 191 |
0.111 (0.21) |
0.0811 (0.165) |
0.0002 (0.00159) |
0.0149 (0.047) |
0.451 (0.563) |
0.777 (0.832) |
0.143 (0.245) |
0.243 (0.357) |
0.0752 (0.157) |
0.00016 (0.00132) |
0.00558 (0.022) |
0.0902 (0.179) |
| 7p loss | 60 (12%) | 441 |
0.391 (0.503) |
1 (1.00) |
0.00072 (0.00424) |
0.0285 (0.0758) |
0.713 (0.78) |
0.88 (0.913) |
0.381 (0.493) |
0.14 (0.244) |
0.024 (0.0675) |
0.00573 (0.0225) |
0.674 (0.757) |
0.199 (0.306) |
| 7q loss | 50 (10%) | 451 |
0.183 (0.289) |
0.0888 (0.177) |
0.0808 (0.165) |
0.359 (0.471) |
0.74 (0.802) |
0.177 (0.283) |
0.00012 (0.00107) |
0.00049 (0.00319) |
0.0654 (0.14) |
0.0404 (0.0962) |
0.7 (0.773) |
0.0141 (0.0458) |
| 11p loss | 169 (34%) | 332 |
0.379 (0.492) |
0.442 (0.556) |
0.00204 (0.01) |
0.0103 (0.0353) |
0.17 (0.278) |
0.212 (0.322) |
0.24 (0.356) |
0.588 (0.69) |
0.00938 (0.0331) |
0.513 (0.621) |
0.0393 (0.0944) |
0.525 (0.631) |
| 15q loss | 141 (28%) | 360 |
0.634 (0.722) |
0.743 (0.802) |
1e-05 (0.000135) |
0.317 (0.435) |
0.563 (0.664) |
0.13 (0.233) |
0.0464 (0.106) |
0.239 (0.355) |
0.00318 (0.0141) |
0.148 (0.251) |
0.0234 (0.067) |
0.0861 (0.173) |
| 3q gain | 315 (63%) | 186 |
0.721 (0.787) |
0.735 (0.799) |
0.00029 (0.00216) |
0.00752 (0.0278) |
0.425 (0.541) |
0.325 (0.441) |
0.284 (0.402) |
0.446 (0.559) |
0.142 (0.245) |
0.0424 (0.0997) |
0.0911 (0.18) |
0.126 (0.227) |
| 5p gain | 309 (62%) | 192 |
0.945 (0.964) |
0.626 (0.72) |
0.00081 (0.00463) |
0.0439 (0.103) |
0.695 (0.77) |
0.976 (0.986) |
0.219 (0.331) |
0.349 (0.465) |
0.628 (0.72) |
0.033 (0.0832) |
0.0544 (0.121) |
0.172 (0.279) |
| 6p gain | 108 (22%) | 393 |
0.113 (0.211) |
0.112 (0.21) |
1e-05 (0.000135) |
0.0626 (0.135) |
0.424 (0.54) |
0.52 (0.626) |
0.00012 (0.00107) |
0.00448 (0.0188) |
0.137 (0.238) |
0.204 (0.312) |
0.955 (0.971) |
0.578 (0.679) |
| 8p gain | 129 (26%) | 372 |
0.631 (0.722) |
0.357 (0.47) |
0.297 (0.416) |
0.19 (0.296) |
0.849 (0.889) |
0.981 (0.986) |
0.0132 (0.0436) |
0.0137 (0.0446) |
0.169 (0.276) |
0.0191 (0.0572) |
0.872 (0.907) |
0.964 (0.977) |
| 10q gain | 44 (9%) | 457 |
0.121 (0.222) |
0.144 (0.246) |
0.0115 (0.0391) |
0.112 (0.211) |
0.497 (0.606) |
0.554 (0.656) |
0.0341 (0.085) |
0.00549 (0.0219) |
0.89 (0.918) |
0.164 (0.271) |
0.135 (0.237) |
0.473 (0.584) |
| 11p gain | 75 (15%) | 426 |
0.503 (0.611) |
0.559 (0.662) |
0.343 (0.459) |
0.238 (0.354) |
0.4 (0.512) |
0.0803 (0.165) |
0.338 (0.456) |
0.693 (0.77) |
0.0472 (0.108) |
0.133 (0.236) |
0.00162 (0.00852) |
0.00485 (0.0198) |
| 19q gain | 163 (33%) | 338 |
0.0598 (0.13) |
0.105 (0.201) |
0.00012 (0.00107) |
0.43 (0.544) |
0.658 (0.745) |
0.905 (0.931) |
0.0254 (0.0702) |
0.69 (0.769) |
0.218 (0.33) |
0.53 (0.636) |
0.0559 (0.123) |
0.0462 (0.106) |
| 1q loss | 60 (12%) | 441 |
0.647 (0.734) |
0.867 (0.903) |
0.00086 (0.00486) |
0.0265 (0.0727) |
0.611 (0.71) |
0.302 (0.42) |
0.0623 (0.135) |
0.0277 (0.0742) |
0.631 (0.722) |
0.0841 (0.17) |
0.0683 (0.146) |
0.319 (0.436) |
| 2p loss | 24 (5%) | 477 |
0.077 (0.16) |
0.129 (0.233) |
0.0323 (0.0825) |
0.472 (0.584) |
0.499 (0.608) |
0.304 (0.421) |
0.811 (0.858) |
0.0951 (0.186) |
0.00036 (0.0026) |
0.38 (0.493) |
0.0459 (0.106) |
0.0853 (0.172) |
| 5p loss | 79 (16%) | 422 |
0.875 (0.91) |
0.735 (0.799) |
1e-05 (0.000135) |
0.00038 (0.00267) |
0.163 (0.271) |
0.0234 (0.067) |
0.163 (0.271) |
0.131 (0.234) |
0.145 (0.247) |
0.293 (0.412) |
0.324 (0.441) |
0.346 (0.463) |
| 13q loss | 311 (62%) | 190 |
0.471 (0.584) |
0.712 (0.78) |
2e-05 (0.000232) |
0.0291 (0.0763) |
0.513 (0.621) |
0.75 (0.806) |
0.396 (0.51) |
0.703 (0.774) |
0.194 (0.3) |
0.106 (0.202) |
0.0276 (0.0742) |
0.0991 (0.192) |
| 18p loss | 141 (28%) | 360 |
0.942 (0.961) |
0.743 (0.802) |
0.029 (0.0762) |
0.0116 (0.0391) |
0.817 (0.862) |
0.376 (0.489) |
0.22 (0.332) |
0.0556 (0.123) |
0.0896 (0.178) |
0.0648 (0.139) |
0.0157 (0.0489) |
0.199 (0.306) |
| 18q loss | 190 (38%) | 311 |
0.489 (0.6) |
0.236 (0.351) |
0.0038 (0.0164) |
0.0463 (0.106) |
0.473 (0.584) |
0.571 (0.672) |
0.515 (0.623) |
0.132 (0.235) |
0.114 (0.212) |
0.164 (0.271) |
0.0342 (0.0851) |
0.226 (0.339) |
| 20p loss | 42 (8%) | 459 |
0.191 (0.297) |
0.141 (0.245) |
0.13 (0.234) |
0.0413 (0.0978) |
0.864 (0.901) |
0.304 (0.421) |
0.164 (0.271) |
0.03 (0.0776) |
0.28 (0.399) |
0.0634 (0.137) |
0.0372 (0.0906) |
0.439 (0.554) |
| 20q gain | 251 (50%) | 250 |
0.503 (0.611) |
0.447 (0.559) |
1e-05 (0.000135) |
0.341 (0.459) |
0.632 (0.722) |
0.842 (0.883) |
0.291 (0.41) |
0.175 (0.282) |
0.794 (0.845) |
0.0345 (0.0854) |
0.105 (0.201) |
0.202 (0.31) |
| 8q loss | 54 (11%) | 447 |
0.07 (0.149) |
0.277 (0.397) |
0.21 (0.32) |
0.189 (0.295) |
0.296 (0.415) |
0.173 (0.28) |
0.111 (0.21) |
0.0244 (0.0684) |
0.0368 (0.0899) |
0.25 (0.365) |
0.744 (0.802) |
0.534 (0.639) |
| 11q loss | 143 (29%) | 358 |
0.988 (0.992) |
0.709 (0.778) |
0.0161 (0.0498) |
0.0143 (0.0462) |
0.749 (0.806) |
0.692 (0.77) |
0.481 (0.593) |
0.622 (0.72) |
0.611 (0.71) |
0.4 (0.512) |
0.501 (0.61) |
0.69 (0.769) |
| 12p loss | 39 (8%) | 462 |
0.034 (0.0849) |
0.0056 (0.022) |
0.246 (0.36) |
0.162 (0.27) |
0.399 (0.512) |
0.442 (0.556) |
0.93 (0.954) |
0.112 (0.21) |
0.0501 (0.113) |
0.0827 (0.167) |
0.821 (0.865) |
0.258 (0.374) |
| 1p gain | 91 (18%) | 410 |
0.113 (0.211) |
0.0927 (0.183) |
0.0222 (0.0642) |
0.822 (0.865) |
0.0737 (0.154) |
0.978 (0.986) |
0.336 (0.454) |
0.135 (0.237) |
0.0514 (0.115) |
0.304 (0.421) |
0.173 (0.28) |
0.86 (0.898) |
| 4q gain | 21 (4%) | 480 |
0.889 (0.918) |
0.55 (0.654) |
0.0289 (0.0762) |
0.84 (0.883) |
0.543 (0.647) |
0.0716 (0.151) |
0.702 (0.774) |
0.957 (0.973) |
0.279 (0.399) |
0.463 (0.575) |
0.351 (0.467) |
0.179 (0.286) |
| 5q gain | 97 (19%) | 404 |
0.776 (0.831) |
0.23 (0.344) |
0.241 (0.356) |
0.269 (0.388) |
0.296 (0.415) |
0.861 (0.898) |
0.27 (0.388) |
0.0564 (0.124) |
0.34 (0.458) |
0.188 (0.294) |
0.0827 (0.167) |
0.0294 (0.0763) |
| 13q gain | 39 (8%) | 462 |
0.677 (0.76) |
0.662 (0.748) |
0.0107 (0.0363) |
0.17 (0.278) |
0.56 (0.663) |
0.328 (0.444) |
0.531 (0.636) |
0.707 (0.777) |
0.194 (0.3) |
0.592 (0.694) |
0.164 (0.271) |
0.78 (0.834) |
| 16p gain | 86 (17%) | 415 |
0.437 (0.553) |
0.543 (0.647) |
0.00941 (0.0331) |
0.82 (0.864) |
0.922 (0.948) |
0.539 (0.644) |
0.633 (0.722) |
0.742 (0.802) |
0.426 (0.541) |
0.0571 (0.125) |
0.553 (0.656) |
0.431 (0.545) |
| 16q gain | 85 (17%) | 416 |
0.992 (0.994) |
0.902 (0.929) |
0.0102 (0.0353) |
0.669 (0.753) |
0.416 (0.531) |
0.235 (0.351) |
0.107 (0.203) |
0.605 (0.706) |
0.202 (0.31) |
0.0707 (0.15) |
0.346 (0.463) |
0.356 (0.47) |
| 12q loss | 47 (9%) | 454 |
0.369 (0.482) |
0.141 (0.245) |
0.115 (0.214) |
0.844 (0.885) |
0.62 (0.719) |
0.187 (0.294) |
0.678 (0.76) |
0.803 (0.852) |
0.0287 (0.0761) |
0.198 (0.305) |
0.529 (0.636) |
0.134 (0.237) |
| 19q loss | 110 (22%) | 391 |
0.604 (0.705) |
0.256 (0.373) |
0.00503 (0.0205) |
0.241 (0.356) |
0.177 (0.283) |
0.886 (0.916) |
0.978 (0.986) |
0.486 (0.597) |
0.414 (0.529) |
0.168 (0.275) |
0.19 (0.296) |
0.486 (0.597) |
| 3p gain | 108 (22%) | 393 |
0.95 (0.968) |
0.704 (0.774) |
0.111 (0.21) |
0.173 (0.28) |
0.939 (0.959) |
0.639 (0.727) |
0.444 (0.558) |
0.174 (0.282) |
0.326 (0.442) |
0.43 (0.544) |
0.809 (0.857) |
0.227 (0.34) |
| 21q gain | 57 (11%) | 444 |
0.851 (0.889) |
0.815 (0.861) |
0.776 (0.831) |
0.541 (0.646) |
0.286 (0.403) |
0.564 (0.665) |
0.282 (0.401) |
0.776 (0.831) |
0.801 (0.852) |
0.466 (0.579) |
0.153 (0.259) |
0.642 (0.729) |
| 3q loss | 73 (15%) | 428 |
0.981 (0.986) |
0.927 (0.952) |
0.713 (0.78) |
0.52 (0.627) |
0.177 (0.283) |
0.218 (0.329) |
0.807 (0.855) |
0.271 (0.389) |
0.577 (0.678) |
0.342 (0.459) |
0.445 (0.559) |
0.247 (0.361) |
P value = 0.0222 (Fisher's exact test), Q value = 0.064
Table S1. Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 1P GAIN MUTATED | 11 | 13 | 7 | 15 | 27 | 18 |
| 1P GAIN WILD-TYPE | 32 | 102 | 22 | 72 | 142 | 40 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00096
Table S2. Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 1Q GAIN MUTATED | 17 | 34 | 12 | 22 | 88 | 29 |
| 1Q GAIN WILD-TYPE | 26 | 81 | 17 | 65 | 81 | 29 |
Figure S2. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00662 (Fisher's exact test), Q value = 0.025
Table S3. Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 1Q GAIN MUTATED | 32 | 42 | 30 | 35 |
| 1Q GAIN WILD-TYPE | 58 | 53 | 27 | 90 |
Figure S3. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00752 (Fisher's exact test), Q value = 0.028
Table S4. Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 1Q GAIN MUTATED | 34 | 77 | 63 | 28 |
| 1Q GAIN WILD-TYPE | 72 | 73 | 96 | 55 |
Figure S4. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00053 (Fisher's exact test), Q value = 0.0033
Table S5. Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 1Q GAIN MUTATED | 53 | 93 | 56 |
| 1Q GAIN WILD-TYPE | 125 | 96 | 75 |
Figure S5. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00026 (Fisher's exact test), Q value = 0.002
Table S6. Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 1Q GAIN MUTATED | 81 | 29 | 34 | 44 |
| 1Q GAIN WILD-TYPE | 103 | 58 | 90 | 36 |
Figure S6. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00304 (Fisher's exact test), Q value = 0.014
Table S7. Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 1Q GAIN MUTATED | 49 | 50 | 65 | 24 |
| 1Q GAIN WILD-TYPE | 40 | 68 | 134 | 45 |
Figure S7. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0221 (Fisher's exact test), Q value = 0.064
Table S8. Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 1Q GAIN MUTATED | 17 | 51 | 17 | 39 |
| 1Q GAIN WILD-TYPE | 44 | 64 | 49 | 53 |
Figure S8. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0204 (Fisher's exact test), Q value = 0.06
Table S9. Gene #2: '1q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 1Q GAIN MUTATED | 11 | 82 | 31 |
| 1Q GAIN WILD-TYPE | 26 | 106 | 78 |
Figure S9. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.017 (Fisher's exact test), Q value = 0.052
Table S10. Gene #3: '2p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 2P GAIN MUTATED | 17 | 31 | 15 |
| 2P GAIN WILD-TYPE | 30 | 25 | 36 |
Figure S10. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S11. Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 2P GAIN MUTATED | 14 | 30 | 12 | 25 | 106 | 36 |
| 2P GAIN WILD-TYPE | 29 | 85 | 17 | 62 | 63 | 22 |
Figure S11. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S12. Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 2P GAIN MUTATED | 31 | 61 | 35 | 44 |
| 2P GAIN WILD-TYPE | 59 | 34 | 22 | 81 |
Figure S12. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0168 (Fisher's exact test), Q value = 0.051
Table S13. Gene #3: '2p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 2P GAIN MUTATED | 45 | 44 | 53 | 11 |
| 2P GAIN WILD-TYPE | 60 | 65 | 33 | 15 |
Figure S13. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S14. Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 2P GAIN MUTATED | 33 | 93 | 71 | 24 |
| 2P GAIN WILD-TYPE | 73 | 57 | 88 | 59 |
Figure S14. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S15. Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 2P GAIN MUTATED | 61 | 112 | 48 |
| 2P GAIN WILD-TYPE | 117 | 77 | 83 |
Figure S15. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00289 (Fisher's exact test), Q value = 0.013
Table S16. Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 2P GAIN MUTATED | 84 | 49 | 40 | 41 |
| 2P GAIN WILD-TYPE | 100 | 38 | 84 | 39 |
Figure S16. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0315 (Fisher's exact test), Q value = 0.081
Table S17. Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 2P GAIN MUTATED | 44 | 50 | 99 | 21 |
| 2P GAIN WILD-TYPE | 45 | 68 | 100 | 48 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00169 (Fisher's exact test), Q value = 0.0088
Table S18. Gene #3: '2p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 2P GAIN MUTATED | 26 | 61 | 18 | 51 |
| 2P GAIN WILD-TYPE | 35 | 54 | 48 | 41 |
Figure S18. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00291 (Fisher's exact test), Q value = 0.013
Table S19. Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 2P GAIN MUTATED | 15 | 103 | 38 |
| 2P GAIN WILD-TYPE | 22 | 85 | 71 |
Figure S19. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00032
Table S20. Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 2Q GAIN MUTATED | 8 | 20 | 8 | 15 | 68 | 24 |
| 2Q GAIN WILD-TYPE | 35 | 95 | 21 | 72 | 101 | 34 |
Figure S20. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0028
Table S21. Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 2Q GAIN MUTATED | 22 | 58 | 48 | 13 |
| 2Q GAIN WILD-TYPE | 84 | 92 | 111 | 70 |
Figure S21. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0147 (Fisher's exact test), Q value = 0.047
Table S22. Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 2Q GAIN MUTATED | 39 | 67 | 35 |
| 2Q GAIN WILD-TYPE | 139 | 122 | 96 |
Figure S22. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0284 (Fisher's exact test), Q value = 0.076
Table S23. Gene #4: '2q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 2Q GAIN MUTATED | 60 | 29 | 23 | 24 |
| 2Q GAIN WILD-TYPE | 124 | 58 | 101 | 56 |
Figure S23. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0178 (Fisher's exact test), Q value = 0.054
Table S24. Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 2Q GAIN MUTATED | 13 | 42 | 12 | 32 |
| 2Q GAIN WILD-TYPE | 48 | 73 | 54 | 60 |
Figure S24. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0446 (Fisher's exact test), Q value = 0.1
Table S25. Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 2Q GAIN MUTATED | 6 | 65 | 28 |
| 2Q GAIN WILD-TYPE | 31 | 123 | 81 |
Figure S25. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00029 (Fisher's exact test), Q value = 0.0022
Table S26. Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 3Q GAIN MUTATED | 27 | 54 | 23 | 58 | 107 | 46 |
| 3Q GAIN WILD-TYPE | 16 | 61 | 6 | 29 | 62 | 12 |
Figure S26. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00752 (Fisher's exact test), Q value = 0.028
Table S27. Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 3Q GAIN MUTATED | 64 | 58 | 43 | 66 |
| 3Q GAIN WILD-TYPE | 26 | 37 | 14 | 59 |
Figure S27. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0424 (Fisher's exact test), Q value = 0.1
Table S28. Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 3Q GAIN MUTATED | 56 | 74 | 134 | 33 |
| 3Q GAIN WILD-TYPE | 33 | 44 | 65 | 36 |
Figure S28. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00036 (Fisher's exact test), Q value = 0.0026
Table S29. Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 4P GAIN MUTATED | 4 | 5 | 5 | 5 | 3 | 9 |
| 4P GAIN WILD-TYPE | 39 | 110 | 24 | 82 | 166 | 49 |
Figure S29. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0415 (Fisher's exact test), Q value = 0.098
Table S30. Gene #7: '4p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 4P GAIN MUTATED | 9 | 1 | 2 | 6 |
| 4P GAIN WILD-TYPE | 81 | 94 | 55 | 119 |
Figure S30. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0197 (Fisher's exact test), Q value = 0.059
Table S31. Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 4P GAIN MUTATED | 5 | 3 | 16 | 6 |
| 4P GAIN WILD-TYPE | 101 | 147 | 143 | 77 |
Figure S31. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.0091
Table S32. Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 4P GAIN MUTATED | 15 | 3 | 12 |
| 4P GAIN WILD-TYPE | 163 | 186 | 119 |
Figure S32. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0289 (Fisher's exact test), Q value = 0.076
Table S33. Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 4Q GAIN MUTATED | 2 | 2 | 5 | 4 | 5 | 3 |
| 4Q GAIN WILD-TYPE | 41 | 113 | 24 | 83 | 164 | 55 |
Figure S33. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00081 (Fisher's exact test), Q value = 0.0046
Table S34. Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 5P GAIN MUTATED | 27 | 66 | 19 | 46 | 101 | 50 |
| 5P GAIN WILD-TYPE | 16 | 49 | 10 | 41 | 68 | 8 |
Figure S34. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0439 (Fisher's exact test), Q value = 0.1
Table S35. Gene #9: '5p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 5P GAIN MUTATED | 67 | 52 | 35 | 78 |
| 5P GAIN WILD-TYPE | 23 | 43 | 22 | 47 |
Figure S35. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.033 (Fisher's exact test), Q value = 0.083
Table S36. Gene #9: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 5P GAIN MUTATED | 56 | 66 | 137 | 36 |
| 5P GAIN WILD-TYPE | 33 | 52 | 62 | 33 |
Figure S36. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0294 (Fisher's exact test), Q value = 0.076
Table S37. Gene #10: '5q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 5Q GAIN MUTATED | 13 | 36 | 16 |
| 5Q GAIN WILD-TYPE | 24 | 152 | 93 |
Figure S37. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S38. Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 6P GAIN MUTATED | 9 | 11 | 5 | 20 | 37 | 26 |
| 6P GAIN WILD-TYPE | 34 | 104 | 24 | 67 | 132 | 32 |
Figure S38. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 0.0011
Table S39. Gene #11: '6p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 6P GAIN MUTATED | 11 | 26 | 51 | 19 |
| 6P GAIN WILD-TYPE | 95 | 124 | 108 | 64 |
Figure S39. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00448 (Fisher's exact test), Q value = 0.019
Table S40. Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 6P GAIN MUTATED | 36 | 30 | 41 |
| 6P GAIN WILD-TYPE | 142 | 159 | 90 |
Figure S40. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0245 (Fisher's exact test), Q value = 0.069
Table S41. Gene #12: '6q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 6Q GAIN MUTATED | 9 | 3 | 6 | 9 |
| 6Q GAIN WILD-TYPE | 32 | 47 | 28 | 20 |
Figure S41. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.024 (Fisher's exact test), Q value = 0.068
Table S42. Gene #12: '6q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 6Q GAIN MUTATED | 10 | 4 | 13 |
| 6Q GAIN WILD-TYPE | 37 | 52 | 38 |
Figure S42. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.0013
Table S43. Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 6Q GAIN MUTATED | 8 | 9 | 3 | 16 | 34 | 22 |
| 6Q GAIN WILD-TYPE | 35 | 106 | 26 | 71 | 135 | 36 |
Figure S43. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00329 (Fisher's exact test), Q value = 0.015
Table S44. Gene #12: '6q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 6Q GAIN MUTATED | 13 | 20 | 44 | 15 |
| 6Q GAIN WILD-TYPE | 93 | 130 | 115 | 68 |
Figure S44. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00619 (Fisher's exact test), Q value = 0.024
Table S45. Gene #12: '6q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 6Q GAIN MUTATED | 35 | 23 | 34 |
| 6Q GAIN WILD-TYPE | 143 | 166 | 97 |
Figure S45. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0104 (Fisher's exact test), Q value = 0.036
Table S46. Gene #13: '7p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 7P GAIN MUTATED | 23 | 38 | 20 |
| 7P GAIN WILD-TYPE | 24 | 18 | 31 |
Figure S46. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S47. Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 7P GAIN MUTATED | 28 | 46 | 14 | 18 | 102 | 30 |
| 7P GAIN WILD-TYPE | 15 | 69 | 15 | 69 | 67 | 28 |
Figure S47. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00289 (Fisher's exact test), Q value = 0.013
Table S48. Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 7P GAIN MUTATED | 39 | 59 | 24 | 47 |
| 7P GAIN WILD-TYPE | 51 | 36 | 33 | 78 |
Figure S48. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00032
Table S49. Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 7P GAIN MUTATED | 44 | 94 | 69 | 29 |
| 7P GAIN WILD-TYPE | 62 | 56 | 90 | 54 |
Figure S49. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S50. Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 7P GAIN MUTATED | 65 | 119 | 52 |
| 7P GAIN WILD-TYPE | 113 | 70 | 79 |
Figure S50. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00222 (Fisher's exact test), Q value = 0.011
Table S51. Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 7P GAIN MUTATED | 98 | 42 | 43 | 47 |
| 7P GAIN WILD-TYPE | 86 | 45 | 81 | 33 |
Figure S51. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00063 (Fisher's exact test), Q value = 0.0039
Table S52. Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 7P GAIN MUTATED | 60 | 57 | 84 | 29 |
| 7P GAIN WILD-TYPE | 29 | 61 | 115 | 40 |
Figure S52. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0197 (Fisher's exact test), Q value = 0.059
Table S53. Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 7P GAIN MUTATED | 25 | 51 | 23 | 54 |
| 7P GAIN WILD-TYPE | 36 | 64 | 43 | 38 |
Figure S53. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00379 (Fisher's exact test), Q value = 0.016
Table S54. Gene #14: '7q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 7Q GAIN MUTATED | 20 | 34 | 11 | 10 |
| 7Q GAIN WILD-TYPE | 21 | 16 | 23 | 19 |
Figure S54. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.0023
Table S55. Gene #14: '7q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 7Q GAIN MUTATED | 22 | 38 | 15 |
| 7Q GAIN WILD-TYPE | 25 | 18 | 36 |
Figure S55. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S56. Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 7Q GAIN MUTATED | 26 | 33 | 15 | 13 | 106 | 27 |
| 7Q GAIN WILD-TYPE | 17 | 82 | 14 | 74 | 63 | 31 |
Figure S56. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0015
Table S57. Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 7Q GAIN MUTATED | 34 | 57 | 24 | 39 |
| 7Q GAIN WILD-TYPE | 56 | 38 | 33 | 86 |
Figure S57. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0323 (Fisher's exact test), Q value = 0.082
Table S58. Gene #14: '7q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 7Q GAIN MUTATED | 41 | 41 | 48 | 14 |
| 7Q GAIN WILD-TYPE | 64 | 68 | 38 | 12 |
Figure S58. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S59. Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 7Q GAIN MUTATED | 38 | 97 | 52 | 31 |
| 7Q GAIN WILD-TYPE | 68 | 53 | 107 | 52 |
Figure S59. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S60. Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 7Q GAIN MUTATED | 55 | 120 | 43 |
| 7Q GAIN WILD-TYPE | 123 | 69 | 88 |
Figure S60. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00087
Table S61. Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 7Q GAIN MUTATED | 88 | 38 | 37 | 49 |
| 7Q GAIN WILD-TYPE | 96 | 49 | 87 | 31 |
Figure S61. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00089 (Fisher's exact test), Q value = 0.005
Table S62. Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 7Q GAIN MUTATED | 57 | 47 | 81 | 27 |
| 7Q GAIN WILD-TYPE | 32 | 71 | 118 | 42 |
Figure S62. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0146 (Fisher's exact test), Q value = 0.047
Table S63. Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 7Q GAIN MUTATED | 20 | 49 | 21 | 50 |
| 7Q GAIN WILD-TYPE | 41 | 66 | 45 | 42 |
Figure S63. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0178 (Fisher's exact test), Q value = 0.054
Table S64. Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 7Q GAIN MUTATED | 8 | 87 | 45 |
| 7Q GAIN WILD-TYPE | 29 | 101 | 64 |
Figure S64. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0132 (Fisher's exact test), Q value = 0.044
Table S65. Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 8P GAIN MUTATED | 25 | 26 | 50 | 27 |
| 8P GAIN WILD-TYPE | 81 | 124 | 109 | 56 |
Figure S65. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.045
Table S66. Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 8P GAIN MUTATED | 54 | 35 | 39 |
| 8P GAIN WILD-TYPE | 124 | 154 | 92 |
Figure S66. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0191 (Fisher's exact test), Q value = 0.057
Table S67. Gene #15: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 8P GAIN MUTATED | 16 | 22 | 62 | 21 |
| 8P GAIN WILD-TYPE | 73 | 96 | 137 | 48 |
Figure S67. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0264 (Fisher's exact test), Q value = 0.072
Table S68. Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 8Q GAIN MUTATED | 27 | 20 | 30 |
| 8Q GAIN WILD-TYPE | 20 | 36 | 21 |
Figure S68. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00045 (Fisher's exact test), Q value = 0.0031
Table S69. Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 8Q GAIN MUTATED | 30 | 53 | 19 | 42 | 72 | 40 |
| 8Q GAIN WILD-TYPE | 13 | 62 | 10 | 45 | 97 | 18 |
Figure S69. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00198 (Fisher's exact test), Q value = 0.0098
Table S70. Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 8Q GAIN MUTATED | 59 | 57 | 93 | 45 |
| 8Q GAIN WILD-TYPE | 47 | 93 | 66 | 38 |
Figure S70. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 6e-04
Table S71. Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 8Q GAIN MUTATED | 107 | 72 | 75 |
| 8Q GAIN WILD-TYPE | 71 | 117 | 56 |
Figure S71. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00225 (Fisher's exact test), Q value = 0.011
Table S72. Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 8Q GAIN MUTATED | 89 | 50 | 73 | 27 |
| 8Q GAIN WILD-TYPE | 95 | 37 | 51 | 53 |
Figure S72. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00194 (Fisher's exact test), Q value = 0.0097
Table S73. Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 8Q GAIN MUTATED | 33 | 51 | 116 | 39 |
| 8Q GAIN WILD-TYPE | 56 | 67 | 83 | 30 |
Figure S73. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0272 (Fisher's exact test), Q value = 0.074
Table S74. Gene #17: '9p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 9P GAIN MUTATED | 1 | 8 | 9 |
| 9P GAIN WILD-TYPE | 46 | 48 | 42 |
Figure S74. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S75. Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 9P GAIN MUTATED | 6 | 14 | 0 | 1 | 37 | 4 |
| 9P GAIN WILD-TYPE | 37 | 101 | 29 | 86 | 132 | 54 |
Figure S75. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 9e-04 (Fisher's exact test), Q value = 0.005
Table S76. Gene #17: '9p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 9P GAIN MUTATED | 7 | 23 | 10 | 9 |
| 9P GAIN WILD-TYPE | 83 | 72 | 47 | 116 |
Figure S76. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0294 (Fisher's exact test), Q value = 0.076
Table S77. Gene #17: '9p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 79 | 67 | 62 | 60 | 30 | 28 |
| 9P GAIN MUTATED | 14 | 5 | 4 | 9 | 0 | 5 |
| 9P GAIN WILD-TYPE | 65 | 62 | 58 | 51 | 30 | 23 |
Figure S77. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00032
Table S78. Gene #17: '9p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 9P GAIN MUTATED | 3 | 35 | 15 | 9 |
| 9P GAIN WILD-TYPE | 103 | 115 | 144 | 74 |
Figure S78. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S79. Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 9P GAIN MUTATED | 6 | 39 | 17 |
| 9P GAIN WILD-TYPE | 172 | 150 | 114 |
Figure S79. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0328 (Fisher's exact test), Q value = 0.083
Table S80. Gene #17: '9p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 9P GAIN MUTATED | 17 | 19 | 16 | 9 |
| 9P GAIN WILD-TYPE | 72 | 99 | 183 | 60 |
Figure S80. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0405 (Fisher's exact test), Q value = 0.096
Table S81. Gene #17: '9p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 9P GAIN MUTATED | 2 | 13 | 10 | 16 |
| 9P GAIN WILD-TYPE | 59 | 102 | 56 | 76 |
Figure S81. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0294 (Fisher's exact test), Q value = 0.076
Table S82. Gene #18: '9q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 9Q GAIN MUTATED | 3 | 16 | 6 | 6 |
| 9Q GAIN WILD-TYPE | 38 | 34 | 28 | 23 |
Figure S82. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00175 (Fisher's exact test), Q value = 0.009
Table S83. Gene #18: '9q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 9Q GAIN MUTATED | 3 | 19 | 9 |
| 9Q GAIN WILD-TYPE | 44 | 37 | 42 |
Figure S83. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S84. Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 9Q GAIN MUTATED | 4 | 17 | 0 | 3 | 64 | 3 |
| 9Q GAIN WILD-TYPE | 39 | 98 | 29 | 84 | 105 | 55 |
Figure S84. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S85. Gene #18: '9q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 9Q GAIN MUTATED | 7 | 36 | 13 | 10 |
| 9Q GAIN WILD-TYPE | 83 | 59 | 44 | 115 |
Figure S85. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00042
Table S86. Gene #18: '9q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 9Q GAIN MUTATED | 21 | 7 | 28 | 3 |
| 9Q GAIN WILD-TYPE | 84 | 102 | 58 | 23 |
Figure S86. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00317 (Fisher's exact test), Q value = 0.014
Table S87. Gene #18: '9q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 79 | 67 | 62 | 60 | 30 | 28 |
| 9Q GAIN MUTATED | 22 | 14 | 3 | 12 | 2 | 6 |
| 9Q GAIN WILD-TYPE | 57 | 53 | 59 | 48 | 28 | 22 |
Figure S87. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S88. Gene #18: '9q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 9Q GAIN MUTATED | 5 | 58 | 21 | 7 |
| 9Q GAIN WILD-TYPE | 101 | 92 | 138 | 76 |
Figure S88. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S89. Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 9Q GAIN MUTATED | 7 | 64 | 20 |
| 9Q GAIN WILD-TYPE | 171 | 125 | 111 |
Figure S89. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.0012
Table S90. Gene #18: '9q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 9Q GAIN MUTATED | 39 | 12 | 11 | 26 |
| 9Q GAIN WILD-TYPE | 145 | 75 | 113 | 54 |
Figure S90. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00078
Table S91. Gene #18: '9q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 9Q GAIN MUTATED | 30 | 26 | 24 | 8 |
| 9Q GAIN WILD-TYPE | 59 | 92 | 175 | 61 |
Figure S91. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0288 (Fisher's exact test), Q value = 0.076
Table S92. Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 10P GAIN MUTATED | 13 | 12 | 2 | 14 | 24 | 13 |
| 10P GAIN WILD-TYPE | 30 | 103 | 27 | 73 | 145 | 45 |
Figure S92. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.034 (Fisher's exact test), Q value = 0.085
Table S93. Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 10P GAIN MUTATED | 23 | 18 | 29 | 7 |
| 10P GAIN WILD-TYPE | 83 | 132 | 130 | 76 |
Figure S93. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0389 (Fisher's exact test), Q value = 0.094
Table S94. Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 10P GAIN MUTATED | 26 | 22 | 29 |
| 10P GAIN WILD-TYPE | 152 | 167 | 102 |
Figure S94. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00078 (Fisher's exact test), Q value = 0.0045
Table S95. Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 10P GAIN MUTATED | 3 | 18 | 41 | 11 |
| 10P GAIN WILD-TYPE | 86 | 100 | 158 | 58 |
Figure S95. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0422 (Fisher's exact test), Q value = 0.099
Table S96. Gene #19: '10p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 10P GAIN MUTATED | 5 | 40 | 11 |
| 10P GAIN WILD-TYPE | 32 | 148 | 98 |
Figure S96. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0115 (Fisher's exact test), Q value = 0.039
Table S97. Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 10Q GAIN MUTATED | 7 | 7 | 0 | 8 | 11 | 11 |
| 10Q GAIN WILD-TYPE | 36 | 108 | 29 | 79 | 158 | 47 |
Figure S97. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0341 (Fisher's exact test), Q value = 0.085
Table S98. Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 10Q GAIN MUTATED | 12 | 7 | 20 | 4 |
| 10Q GAIN WILD-TYPE | 94 | 143 | 139 | 79 |
Figure S98. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00549 (Fisher's exact test), Q value = 0.022
Table S99. Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 10Q GAIN MUTATED | 16 | 8 | 19 |
| 10Q GAIN WILD-TYPE | 162 | 181 | 112 |
Figure S99. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0472 (Fisher's exact test), Q value = 0.11
Table S100. Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 11P GAIN MUTATED | 37 | 16 | 12 | 9 |
| 11P GAIN WILD-TYPE | 147 | 71 | 112 | 71 |
Figure S100. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00162 (Fisher's exact test), Q value = 0.0085
Table S101. Gene #21: '11p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 11P GAIN MUTATED | 6 | 28 | 3 | 12 |
| 11P GAIN WILD-TYPE | 55 | 87 | 63 | 80 |
Figure S101. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00485 (Fisher's exact test), Q value = 0.02
Table S102. Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 11P GAIN MUTATED | 5 | 37 | 7 |
| 11P GAIN WILD-TYPE | 32 | 151 | 102 |
Figure S102. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00832 (Fisher's exact test), Q value = 0.03
Table S103. Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 11Q GAIN MUTATED | 12 | 5 | 3 | 10 |
| 11Q GAIN WILD-TYPE | 29 | 45 | 31 | 19 |
Figure S103. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0157 (Fisher's exact test), Q value = 0.049
Table S104. Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 11Q GAIN MUTATED | 15 | 13 | 8 | 14 | 27 | 12 |
| 11Q GAIN WILD-TYPE | 28 | 102 | 21 | 73 | 142 | 46 |
Figure S104. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0418 (Fisher's exact test), Q value = 0.099
Table S105. Gene #22: '11q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 11Q GAIN MUTATED | 40 | 24 | 25 |
| 11Q GAIN WILD-TYPE | 138 | 165 | 106 |
Figure S105. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0293 (Fisher's exact test), Q value = 0.076
Table S106. Gene #22: '11q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 11Q GAIN MUTATED | 43 | 19 | 16 | 9 |
| 11Q GAIN WILD-TYPE | 141 | 68 | 108 | 71 |
Figure S106. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00051 (Fisher's exact test), Q value = 0.0033
Table S107. Gene #22: '11q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 11Q GAIN MUTATED | 13 | 29 | 2 | 14 |
| 11Q GAIN WILD-TYPE | 48 | 86 | 64 | 78 |
Figure S107. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0329 (Fisher's exact test), Q value = 0.083
Table S108. Gene #22: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 11Q GAIN MUTATED | 6 | 41 | 11 |
| 11Q GAIN WILD-TYPE | 31 | 147 | 98 |
Figure S108. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0146 (Fisher's exact test), Q value = 0.047
Table S109. Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 12P GAIN MUTATED | 11 | 30 | 13 | 12 |
| 12P GAIN WILD-TYPE | 30 | 20 | 21 | 17 |
Figure S109. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0254 (Fisher's exact test), Q value = 0.07
Table S110. Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 12P GAIN MUTATED | 15 | 32 | 19 |
| 12P GAIN WILD-TYPE | 32 | 24 | 32 |
Figure S110. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S111. Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 12P GAIN MUTATED | 20 | 33 | 11 | 25 | 99 | 38 |
| 12P GAIN WILD-TYPE | 23 | 82 | 18 | 62 | 70 | 20 |
Figure S111. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00442 (Fisher's exact test), Q value = 0.019
Table S112. Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 12P GAIN MUTATED | 46 | 51 | 33 | 43 |
| 12P GAIN WILD-TYPE | 44 | 44 | 24 | 82 |
Figure S112. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0386 (Fisher's exact test), Q value = 0.093
Table S113. Gene #23: '12p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 12P GAIN MUTATED | 43 | 48 | 52 | 11 |
| 12P GAIN WILD-TYPE | 62 | 61 | 34 | 15 |
Figure S113. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S114. Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 12P GAIN MUTATED | 32 | 86 | 80 | 26 |
| 12P GAIN WILD-TYPE | 74 | 64 | 79 | 57 |
Figure S114. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00197 (Fisher's exact test), Q value = 0.0098
Table S115. Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 12P GAIN MUTATED | 62 | 100 | 62 |
| 12P GAIN WILD-TYPE | 116 | 89 | 69 |
Figure S115. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0118 (Fisher's exact test), Q value = 0.039
Table S116. Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 12P GAIN MUTATED | 94 | 41 | 41 | 40 |
| 12P GAIN WILD-TYPE | 90 | 46 | 83 | 40 |
Figure S116. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0053 (Fisher's exact test), Q value = 0.021
Table S117. Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 12P GAIN MUTATED | 51 | 53 | 92 | 20 |
| 12P GAIN WILD-TYPE | 38 | 65 | 107 | 49 |
Figure S117. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00066 (Fisher's exact test), Q value = 0.004
Table S118. Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 12P GAIN MUTATED | 25 | 61 | 17 | 50 |
| 12P GAIN WILD-TYPE | 36 | 54 | 49 | 42 |
Figure S118. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0133 (Fisher's exact test), Q value = 0.044
Table S119. Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 12P GAIN MUTATED | 12 | 99 | 42 |
| 12P GAIN WILD-TYPE | 25 | 89 | 67 |
Figure S119. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00052
Table S120. Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 12Q GAIN MUTATED | 13 | 20 | 6 | 18 | 72 | 22 |
| 12Q GAIN WILD-TYPE | 30 | 95 | 23 | 69 | 97 | 36 |
Figure S120. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00136 (Fisher's exact test), Q value = 0.0073
Table S121. Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 12Q GAIN MUTATED | 29 | 35 | 22 | 21 |
| 12Q GAIN WILD-TYPE | 61 | 60 | 35 | 104 |
Figure S121. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0441 (Fisher's exact test), Q value = 0.1
Table S122. Gene #24: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 12Q GAIN MUTATED | 31 | 28 | 35 | 4 |
| 12Q GAIN WILD-TYPE | 74 | 81 | 51 | 22 |
Figure S122. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00751 (Fisher's exact test), Q value = 0.028
Table S123. Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 12Q GAIN MUTATED | 21 | 59 | 47 | 22 |
| 12Q GAIN WILD-TYPE | 85 | 91 | 112 | 61 |
Figure S123. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00285 (Fisher's exact test), Q value = 0.013
Table S124. Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 12Q GAIN MUTATED | 37 | 64 | 48 |
| 12Q GAIN WILD-TYPE | 141 | 125 | 83 |
Figure S124. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0155 (Fisher's exact test), Q value = 0.049
Table S125. Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 12Q GAIN MUTATED | 67 | 23 | 25 | 26 |
| 12Q GAIN WILD-TYPE | 117 | 64 | 99 | 54 |
Figure S125. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0294 (Fisher's exact test), Q value = 0.076
Table S126. Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 12Q GAIN MUTATED | 14 | 35 | 11 | 34 |
| 12Q GAIN WILD-TYPE | 47 | 80 | 55 | 58 |
Figure S126. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00073 (Fisher's exact test), Q value = 0.0043
Table S127. Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 12Q GAIN MUTATED | 2 | 63 | 29 |
| 12Q GAIN WILD-TYPE | 35 | 125 | 80 |
Figure S127. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0107 (Fisher's exact test), Q value = 0.036
Table S128. Gene #25: '13q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 13Q GAIN MUTATED | 2 | 5 | 7 | 3 | 16 | 6 |
| 13Q GAIN WILD-TYPE | 41 | 110 | 22 | 84 | 153 | 52 |
Figure S128. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0237 (Fisher's exact test), Q value = 0.067
Table S129. Gene #26: '14q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 14Q GAIN MUTATED | 19 | 11 | 9 |
| 14Q GAIN WILD-TYPE | 28 | 45 | 42 |
Figure S129. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S130. Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 14Q GAIN MUTATED | 30 | 25 | 13 | 9 | 38 | 11 |
| 14Q GAIN WILD-TYPE | 13 | 90 | 16 | 78 | 131 | 47 |
Figure S130. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00351 (Fisher's exact test), Q value = 0.015
Table S131. Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 14Q GAIN MUTATED | 60 | 43 | 23 |
| 14Q GAIN WILD-TYPE | 118 | 146 | 108 |
Figure S131. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0429 (Fisher's exact test), Q value = 0.1
Table S132. Gene #26: '14q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 14Q GAIN MUTATED | 19 | 25 | 10 | 30 |
| 14Q GAIN WILD-TYPE | 42 | 90 | 56 | 62 |
Figure S132. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S133. Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 15Q GAIN MUTATED | 3 | 10 | 9 | 19 | 53 | 13 |
| 15Q GAIN WILD-TYPE | 40 | 105 | 20 | 68 | 116 | 45 |
Figure S133. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00082 (Fisher's exact test), Q value = 0.0047
Table S134. Gene #27: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 15Q GAIN MUTATED | 19 | 32 | 12 | 14 |
| 15Q GAIN WILD-TYPE | 71 | 63 | 45 | 111 |
Figure S134. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00139 (Fisher's exact test), Q value = 0.0074
Table S135. Gene #27: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 15Q GAIN MUTATED | 14 | 48 | 27 | 16 |
| 15Q GAIN WILD-TYPE | 92 | 102 | 132 | 67 |
Figure S135. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0119 (Fisher's exact test), Q value = 0.04
Table S136. Gene #27: '15q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 15Q GAIN MUTATED | 32 | 53 | 20 |
| 15Q GAIN WILD-TYPE | 146 | 136 | 111 |
Figure S136. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0024 (Fisher's exact test), Q value = 0.011
Table S137. Gene #27: '15q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 15Q GAIN MUTATED | 33 | 19 | 20 | 30 |
| 15Q GAIN WILD-TYPE | 151 | 68 | 104 | 50 |
Figure S137. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0253 (Fisher's exact test), Q value = 0.07
Table S138. Gene #27: '15q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 15Q GAIN MUTATED | 29 | 23 | 41 | 9 |
| 15Q GAIN WILD-TYPE | 60 | 95 | 158 | 60 |
Figure S138. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0198 (Fisher's exact test), Q value = 0.059
Table S139. Gene #27: '15q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 15Q GAIN MUTATED | 10 | 31 | 6 | 22 |
| 15Q GAIN WILD-TYPE | 51 | 84 | 60 | 70 |
Figure S139. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00941 (Fisher's exact test), Q value = 0.033
Table S140. Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 16P GAIN MUTATED | 16 | 15 | 5 | 9 | 32 | 9 |
| 16P GAIN WILD-TYPE | 27 | 100 | 24 | 78 | 137 | 49 |
Figure S140. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0102 (Fisher's exact test), Q value = 0.035
Table S141. Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 16Q GAIN MUTATED | 13 | 13 | 8 | 8 | 31 | 12 |
| 16Q GAIN WILD-TYPE | 30 | 102 | 21 | 79 | 138 | 46 |
Figure S141. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00511 (Fisher's exact test), Q value = 0.021
Table S142. Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 17P GAIN MUTATED | 1 | 11 | 1 | 5 |
| 17P GAIN WILD-TYPE | 40 | 39 | 33 | 24 |
Figure S142. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0396 (Fisher's exact test), Q value = 0.095
Table S143. Gene #30: '17p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 17P GAIN MUTATED | 5 | 11 | 2 |
| 17P GAIN WILD-TYPE | 42 | 45 | 49 |
Figure S143. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00015 (Fisher's exact test), Q value = 0.0013
Table S144. Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 17P GAIN MUTATED | 5 | 4 | 4 | 7 | 37 | 8 |
| 17P GAIN WILD-TYPE | 38 | 111 | 25 | 80 | 132 | 50 |
Figure S144. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0047 (Fisher's exact test), Q value = 0.019
Table S145. Gene #30: '17p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 17P GAIN MUTATED | 13 | 20 | 12 | 8 |
| 17P GAIN WILD-TYPE | 77 | 75 | 45 | 117 |
Figure S145. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0123 (Fisher's exact test), Q value = 0.041
Table S146. Gene #30: '17p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 17P GAIN MUTATED | 12 | 7 | 18 | 1 |
| 17P GAIN WILD-TYPE | 93 | 102 | 68 | 25 |
Figure S146. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00037 (Fisher's exact test), Q value = 0.0026
Table S147. Gene #30: '17p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 17P GAIN MUTATED | 8 | 35 | 15 | 7 |
| 17P GAIN WILD-TYPE | 98 | 115 | 144 | 76 |
Figure S147. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00061 (Fisher's exact test), Q value = 0.0038
Table S148. Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 17P GAIN MUTATED | 11 | 37 | 17 |
| 17P GAIN WILD-TYPE | 167 | 152 | 114 |
Figure S148. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00262 (Fisher's exact test), Q value = 0.012
Table S149. Gene #30: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 17P GAIN MUTATED | 23 | 12 | 7 | 19 |
| 17P GAIN WILD-TYPE | 161 | 75 | 117 | 61 |
Figure S149. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0016
Table S150. Gene #31: '17q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 17Q GAIN MUTATED | 6 | 27 | 7 | 11 |
| 17Q GAIN WILD-TYPE | 35 | 23 | 27 | 18 |
Figure S150. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00102 (Fisher's exact test), Q value = 0.0055
Table S151. Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 17Q GAIN MUTATED | 12 | 29 | 10 |
| 17Q GAIN WILD-TYPE | 35 | 27 | 41 |
Figure S151. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S152. Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 17Q GAIN MUTATED | 12 | 18 | 4 | 10 | 93 | 21 |
| 17Q GAIN WILD-TYPE | 31 | 97 | 25 | 77 | 76 | 37 |
Figure S152. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S153. Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 17Q GAIN MUTATED | 24 | 46 | 23 | 23 |
| 17Q GAIN WILD-TYPE | 66 | 49 | 34 | 102 |
Figure S153. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S154. Gene #31: '17q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 17Q GAIN MUTATED | 23 | 27 | 46 | 3 |
| 17Q GAIN WILD-TYPE | 82 | 82 | 40 | 23 |
Figure S154. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S155. Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 17Q GAIN MUTATED | 17 | 77 | 45 | 18 |
| 17Q GAIN WILD-TYPE | 89 | 73 | 114 | 65 |
Figure S155. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S156. Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 17Q GAIN MUTATED | 30 | 89 | 38 |
| 17Q GAIN WILD-TYPE | 148 | 100 | 93 |
Figure S156. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S157. Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 17Q GAIN MUTATED | 65 | 29 | 18 | 35 |
| 17Q GAIN WILD-TYPE | 119 | 58 | 106 | 45 |
Figure S157. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00769 (Fisher's exact test), Q value = 0.028
Table S158. Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 17Q GAIN MUTATED | 40 | 35 | 58 | 14 |
| 17Q GAIN WILD-TYPE | 49 | 83 | 141 | 55 |
Figure S158. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00011 (Fisher's exact test), Q value = 0.001
Table S159. Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 17Q GAIN MUTATED | 11 | 47 | 10 | 35 |
| 17Q GAIN WILD-TYPE | 50 | 68 | 56 | 57 |
Figure S159. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00037 (Fisher's exact test), Q value = 0.0026
Table S160. Gene #31: '17q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 17Q GAIN MUTATED | 6 | 74 | 23 |
| 17Q GAIN WILD-TYPE | 31 | 114 | 86 |
Figure S160. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0147 (Fisher's exact test), Q value = 0.047
Table S161. Gene #32: '18p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 18P GAIN MUTATED | 7 | 23 | 9 | 6 |
| 18P GAIN WILD-TYPE | 34 | 27 | 25 | 23 |
Figure S161. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00066 (Fisher's exact test), Q value = 0.004
Table S162. Gene #32: '18p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 18P GAIN MUTATED | 8 | 27 | 10 |
| 18P GAIN WILD-TYPE | 39 | 29 | 41 |
Figure S162. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S163. Gene #32: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 18P GAIN MUTATED | 16 | 21 | 8 | 10 | 79 | 14 |
| 18P GAIN WILD-TYPE | 27 | 94 | 21 | 77 | 90 | 44 |
Figure S163. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00032
Table S164. Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 18P GAIN MUTATED | 25 | 46 | 18 | 21 |
| 18P GAIN WILD-TYPE | 65 | 49 | 39 | 104 |
Figure S164. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0195 (Fisher's exact test), Q value = 0.058
Table S165. Gene #32: '18p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 79 | 67 | 62 | 60 | 30 | 28 |
| 18P GAIN MUTATED | 22 | 18 | 16 | 31 | 8 | 11 |
| 18P GAIN WILD-TYPE | 57 | 49 | 46 | 29 | 22 | 17 |
Figure S165. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00093 (Fisher's exact test), Q value = 0.0051
Table S166. Gene #32: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 18P GAIN MUTATED | 26 | 63 | 42 | 16 |
| 18P GAIN WILD-TYPE | 80 | 87 | 117 | 67 |
Figure S166. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S167. Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 18P GAIN MUTATED | 34 | 81 | 32 |
| 18P GAIN WILD-TYPE | 144 | 108 | 99 |
Figure S167. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0133 (Fisher's exact test), Q value = 0.044
Table S168. Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 18P GAIN MUTATED | 59 | 29 | 23 | 29 |
| 18P GAIN WILD-TYPE | 125 | 58 | 101 | 51 |
Figure S168. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0474 (Fisher's exact test), Q value = 0.11
Table S169. Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 18P GAIN MUTATED | 5 | 62 | 31 |
| 18P GAIN WILD-TYPE | 32 | 126 | 78 |
Figure S169. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0346 (Fisher's exact test), Q value = 0.085
Table S170. Gene #33: '18q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 18Q GAIN MUTATED | 6 | 19 | 5 | 6 |
| 18Q GAIN WILD-TYPE | 35 | 31 | 29 | 23 |
Figure S170. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0078 (Fisher's exact test), Q value = 0.029
Table S171. Gene #33: '18q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 18Q GAIN MUTATED | 6 | 21 | 9 |
| 18Q GAIN WILD-TYPE | 41 | 35 | 42 |
Figure S171. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S172. Gene #33: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 18Q GAIN MUTATED | 7 | 15 | 5 | 7 | 58 | 10 |
| 18Q GAIN WILD-TYPE | 36 | 100 | 24 | 80 | 111 | 48 |
Figure S172. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.0033
Table S173. Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 18Q GAIN MUTATED | 12 | 32 | 13 | 15 |
| 18Q GAIN WILD-TYPE | 78 | 63 | 44 | 110 |
Figure S173. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00049 (Fisher's exact test), Q value = 0.0032
Table S174. Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 18Q GAIN MUTATED | 14 | 45 | 33 | 8 |
| 18Q GAIN WILD-TYPE | 92 | 105 | 126 | 75 |
Figure S174. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.0015
Table S175. Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 18Q GAIN MUTATED | 21 | 55 | 24 |
| 18Q GAIN WILD-TYPE | 157 | 134 | 107 |
Figure S175. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0253 (Fisher's exact test), Q value = 0.07
Table S176. Gene #34: '19p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 19P GAIN MUTATED | 7 | 16 | 2 | 6 |
| 19P GAIN WILD-TYPE | 34 | 34 | 32 | 23 |
Figure S176. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S177. Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 19P GAIN MUTATED | 6 | 18 | 7 | 7 | 64 | 13 |
| 19P GAIN WILD-TYPE | 37 | 97 | 22 | 80 | 105 | 45 |
Figure S177. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00575 (Fisher's exact test), Q value = 0.022
Table S178. Gene #34: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 19P GAIN MUTATED | 21 | 35 | 14 | 20 |
| 19P GAIN WILD-TYPE | 69 | 60 | 43 | 105 |
Figure S178. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.017 (Fisher's exact test), Q value = 0.052
Table S179. Gene #34: '19p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 19P GAIN MUTATED | 24 | 18 | 31 | 5 |
| 19P GAIN WILD-TYPE | 81 | 91 | 55 | 21 |
Figure S179. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.0012
Table S180. Gene #34: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 19P GAIN MUTATED | 16 | 53 | 34 | 11 |
| 19P GAIN WILD-TYPE | 90 | 97 | 125 | 72 |
Figure S180. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00386 (Fisher's exact test), Q value = 0.017
Table S181. Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 19P GAIN MUTATED | 29 | 58 | 27 |
| 19P GAIN WILD-TYPE | 149 | 131 | 104 |
Figure S181. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00626 (Fisher's exact test), Q value = 0.024
Table S182. Gene #34: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 19P GAIN MUTATED | 51 | 16 | 19 | 27 |
| 19P GAIN WILD-TYPE | 133 | 71 | 105 | 53 |
Figure S182. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00194 (Fisher's exact test), Q value = 0.0097
Table S183. Gene #34: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 19P GAIN MUTATED | 35 | 28 | 36 | 14 |
| 19P GAIN WILD-TYPE | 54 | 90 | 163 | 55 |
Figure S183. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.0011
Table S184. Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 19Q GAIN MUTATED | 14 | 29 | 10 | 14 | 69 | 27 |
| 19Q GAIN WILD-TYPE | 29 | 86 | 19 | 73 | 100 | 31 |
Figure S184. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0254 (Fisher's exact test), Q value = 0.07
Table S185. Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 19Q GAIN MUTATED | 26 | 59 | 55 | 20 |
| 19Q GAIN WILD-TYPE | 80 | 91 | 104 | 63 |
Figure S185. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0462 (Fisher's exact test), Q value = 0.11
Table S186. Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 19Q GAIN MUTATED | 12 | 71 | 26 |
| 19Q GAIN WILD-TYPE | 25 | 117 | 83 |
Figure S186. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00799 (Fisher's exact test), Q value = 0.029
Table S187. Gene #36: '20p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 20P GAIN MUTATED | 24 | 32 | 10 | 12 |
| 20P GAIN WILD-TYPE | 17 | 18 | 24 | 17 |
Figure S187. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00971 (Fisher's exact test), Q value = 0.034
Table S188. Gene #36: '20p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 20P GAIN MUTATED | 27 | 34 | 17 |
| 20P GAIN WILD-TYPE | 20 | 22 | 34 |
Figure S188. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S189. Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 20P GAIN MUTATED | 32 | 44 | 18 | 23 | 107 | 39 |
| 20P GAIN WILD-TYPE | 11 | 71 | 11 | 64 | 62 | 19 |
Figure S189. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0028 (Fisher's exact test), Q value = 0.013
Table S190. Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 20P GAIN MUTATED | 41 | 59 | 39 | 56 |
| 20P GAIN WILD-TYPE | 49 | 36 | 18 | 69 |
Figure S190. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S191. Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 20Q GAIN MUTATED | 35 | 49 | 21 | 25 | 84 | 37 |
| 20Q GAIN WILD-TYPE | 8 | 66 | 8 | 62 | 85 | 21 |
Figure S191. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0345 (Fisher's exact test), Q value = 0.085
Table S192. Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 20Q GAIN MUTATED | 36 | 52 | 113 | 36 |
| 20Q GAIN WILD-TYPE | 53 | 66 | 86 | 33 |
Figure S192. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0149 (Fisher's exact test), Q value = 0.047
Table S193. Gene #39: '22q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 22Q GAIN MUTATED | 20 | 30 | 11 | 8 |
| 22Q GAIN WILD-TYPE | 21 | 20 | 23 | 21 |
Figure S193. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0275 (Fisher's exact test), Q value = 0.074
Table S194. Gene #39: '22q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 22Q GAIN MUTATED | 21 | 32 | 16 |
| 22Q GAIN WILD-TYPE | 26 | 24 | 35 |
Figure S194. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S195. Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 22Q GAIN MUTATED | 20 | 34 | 27 | 20 | 91 | 30 |
| 22Q GAIN WILD-TYPE | 23 | 81 | 2 | 67 | 78 | 28 |
Figure S195. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0144 (Fisher's exact test), Q value = 0.046
Table S196. Gene #39: '22q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 22Q GAIN MUTATED | 42 | 52 | 27 | 42 |
| 22Q GAIN WILD-TYPE | 48 | 43 | 30 | 83 |
Figure S196. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00096 (Fisher's exact test), Q value = 0.0053
Table S197. Gene #39: '22q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 22Q GAIN MUTATED | 45 | 86 | 57 | 32 |
| 22Q GAIN WILD-TYPE | 61 | 64 | 102 | 51 |
Figure S197. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.0013
Table S198. Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 22Q GAIN MUTATED | 84 | 98 | 38 |
| 22Q GAIN WILD-TYPE | 94 | 91 | 93 |
Figure S198. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S199. Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| XP GAIN MUTATED | 9 | 3 | 2 | 11 | 22 | 17 |
| XP GAIN WILD-TYPE | 34 | 112 | 27 | 76 | 147 | 41 |
Figure S199. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00426 (Fisher's exact test), Q value = 0.018
Table S200. Gene #40: 'xp gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| XP GAIN MUTATED | 13 | 17 | 11 | 6 |
| XP GAIN WILD-TYPE | 77 | 78 | 46 | 119 |
Figure S200. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.01 (Fisher's exact test), Q value = 0.035
Table S201. Gene #40: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| XP GAIN MUTATED | 9 | 23 | 28 | 4 |
| XP GAIN WILD-TYPE | 97 | 127 | 131 | 79 |
Figure S201. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00265 (Fisher's exact test), Q value = 0.012
Table S202. Gene #40: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| XP GAIN MUTATED | 30 | 15 | 5 | 9 |
| XP GAIN WILD-TYPE | 154 | 72 | 119 | 71 |
Figure S202. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0498 (Fisher's exact test), Q value = 0.11
Table S203. Gene #41: 'xq gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| XQ GAIN MUTATED | 10 | 14 | 4 |
| XQ GAIN WILD-TYPE | 37 | 42 | 47 |
Figure S203. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00042
Table S204. Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| XQ GAIN MUTATED | 8 | 6 | 3 | 8 | 37 | 17 |
| XQ GAIN WILD-TYPE | 35 | 109 | 26 | 79 | 132 | 41 |
Figure S204. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00111 (Fisher's exact test), Q value = 0.006
Table S205. Gene #41: 'xq gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| XQ GAIN MUTATED | 11 | 25 | 9 | 9 |
| XQ GAIN WILD-TYPE | 79 | 70 | 48 | 116 |
Figure S205. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0188 (Fisher's exact test), Q value = 0.056
Table S206. Gene #41: 'xq gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| XQ GAIN MUTATED | 12 | 35 | 24 | 8 |
| XQ GAIN WILD-TYPE | 94 | 115 | 135 | 75 |
Figure S206. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0106 (Fisher's exact test), Q value = 0.036
Table S207. Gene #41: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| XQ GAIN MUTATED | 20 | 42 | 17 |
| XQ GAIN WILD-TYPE | 158 | 147 | 114 |
Figure S207. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S208. Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 1P LOSS MUTATED | 8 | 29 | 8 | 3 |
| 1P LOSS WILD-TYPE | 33 | 21 | 26 | 26 |
Figure S208. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S209. Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 1P LOSS MUTATED | 8 | 31 | 9 |
| 1P LOSS WILD-TYPE | 39 | 25 | 42 |
Figure S209. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S210. Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 1P LOSS MUTATED | 16 | 19 | 7 | 4 | 100 | 9 |
| 1P LOSS WILD-TYPE | 27 | 96 | 22 | 83 | 69 | 49 |
Figure S210. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S211. Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 1P LOSS MUTATED | 15 | 50 | 27 | 20 |
| 1P LOSS WILD-TYPE | 75 | 45 | 30 | 105 |
Figure S211. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0219 (Fisher's exact test), Q value = 0.064
Table S212. Gene #42: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 1P LOSS MUTATED | 33 | 28 | 40 | 8 |
| 1P LOSS WILD-TYPE | 72 | 81 | 46 | 18 |
Figure S212. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S213. Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 1P LOSS MUTATED | 20 | 85 | 31 | 18 |
| 1P LOSS WILD-TYPE | 86 | 65 | 128 | 65 |
Figure S213. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S214. Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 1P LOSS MUTATED | 28 | 102 | 24 |
| 1P LOSS WILD-TYPE | 150 | 87 | 107 |
Figure S214. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00014 (Fisher's exact test), Q value = 0.0012
Table S215. Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 1P LOSS MUTATED | 59 | 22 | 25 | 40 |
| 1P LOSS WILD-TYPE | 125 | 65 | 99 | 40 |
Figure S215. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S216. Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 1P LOSS MUTATED | 52 | 33 | 51 | 10 |
| 1P LOSS WILD-TYPE | 37 | 85 | 148 | 59 |
Figure S216. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00017 (Fisher's exact test), Q value = 0.0014
Table S217. Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 1P LOSS MUTATED | 15 | 34 | 9 | 42 |
| 1P LOSS WILD-TYPE | 46 | 81 | 57 | 50 |
Figure S217. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00558 (Fisher's exact test), Q value = 0.022
Table S218. Gene #42: '1p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 1P LOSS MUTATED | 4 | 67 | 29 |
| 1P LOSS WILD-TYPE | 33 | 121 | 80 |
Figure S218. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00086 (Fisher's exact test), Q value = 0.0049
Table S219. Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 1Q LOSS MUTATED | 8 | 7 | 4 | 3 | 32 | 6 |
| 1Q LOSS WILD-TYPE | 35 | 108 | 25 | 84 | 137 | 52 |
Figure S219. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0265 (Fisher's exact test), Q value = 0.073
Table S220. Gene #43: '1q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 1Q LOSS MUTATED | 9 | 21 | 9 | 11 |
| 1Q LOSS WILD-TYPE | 81 | 74 | 48 | 114 |
Figure S220. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0277 (Fisher's exact test), Q value = 0.074
Table S221. Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 1Q LOSS MUTATED | 16 | 32 | 11 |
| 1Q LOSS WILD-TYPE | 162 | 157 | 120 |
Figure S221. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0323 (Fisher's exact test), Q value = 0.082
Table S222. Gene #44: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 2P LOSS MUTATED | 6 | 3 | 0 | 2 | 8 | 5 |
| 2P LOSS WILD-TYPE | 37 | 112 | 29 | 85 | 161 | 53 |
Figure S222. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0026
Table S223. Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 2P LOSS MUTATED | 18 | 1 | 1 | 2 |
| 2P LOSS WILD-TYPE | 166 | 86 | 123 | 78 |
Figure S223. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0459 (Fisher's exact test), Q value = 0.11
Table S224. Gene #44: '2p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 2P LOSS MUTATED | 0 | 7 | 0 | 4 |
| 2P LOSS WILD-TYPE | 61 | 108 | 66 | 88 |
Figure S224. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0226 (Fisher's exact test), Q value = 0.065
Table S225. Gene #45: '2q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 2Q LOSS MUTATED | 6 | 5 | 0 | 5 | 19 | 9 |
| 2Q LOSS WILD-TYPE | 37 | 110 | 29 | 82 | 150 | 49 |
Figure S225. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0235 (Fisher's exact test), Q value = 0.067
Table S226. Gene #45: '2q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 2Q LOSS MUTATED | 9 | 8 | 9 | 4 |
| 2Q LOSS WILD-TYPE | 81 | 87 | 48 | 121 |
Figure S226. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00462 (Fisher's exact test), Q value = 0.019
Table S227. Gene #45: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 2Q LOSS MUTATED | 25 | 9 | 3 | 6 |
| 2Q LOSS WILD-TYPE | 159 | 78 | 121 | 74 |
Figure S227. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0166 (Fisher's exact test), Q value = 0.051
Table S228. Gene #45: '2q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 2Q LOSS MUTATED | 6 | 11 | 0 | 10 |
| 2Q LOSS WILD-TYPE | 55 | 104 | 66 | 82 |
Figure S228. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.0016
Table S229. Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 3P LOSS MUTATED | 33 | 49 | 20 | 59 | 110 | 39 |
| 3P LOSS WILD-TYPE | 10 | 66 | 9 | 28 | 59 | 19 |
Figure S229. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0149 (Fisher's exact test), Q value = 0.047
Table S230. Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 3P LOSS MUTATED | 64 | 61 | 37 | 63 |
| 3P LOSS WILD-TYPE | 26 | 34 | 20 | 62 |
Figure S230. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.0013
Table S231. Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 3P LOSS MUTATED | 61 | 81 | 123 | 26 |
| 3P LOSS WILD-TYPE | 28 | 37 | 76 | 43 |
Figure S231. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00558 (Fisher's exact test), Q value = 0.022
Table S232. Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 3P LOSS MUTATED | 38 | 77 | 28 | 62 |
| 3P LOSS WILD-TYPE | 23 | 38 | 38 | 30 |
Figure S232. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00049 (Fisher's exact test), Q value = 0.0032
Table S233. Gene #48: '4p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 4P LOSS MUTATED | 30 | 39 | 12 | 17 |
| 4P LOSS WILD-TYPE | 11 | 11 | 22 | 12 |
Figure S233. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00052
Table S234. Gene #48: '4p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 4P LOSS MUTATED | 33 | 45 | 20 |
| 4P LOSS WILD-TYPE | 14 | 11 | 31 |
Figure S234. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S235. Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 4P LOSS MUTATED | 30 | 44 | 15 | 49 | 144 | 33 |
| 4P LOSS WILD-TYPE | 13 | 71 | 14 | 38 | 25 | 25 |
Figure S235. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S236. Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 4P LOSS MUTATED | 54 | 74 | 41 | 60 |
| 4P LOSS WILD-TYPE | 36 | 21 | 16 | 65 |
Figure S236. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00471 (Fisher's exact test), Q value = 0.019
Table S237. Gene #48: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 4P LOSS MUTATED | 65 | 67 | 71 | 17 |
| 4P LOSS WILD-TYPE | 40 | 42 | 15 | 9 |
Figure S237. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0266 (Fisher's exact test), Q value = 0.073
Table S238. Gene #48: '4p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 79 | 67 | 62 | 60 | 30 | 28 |
| 4P LOSS MUTATED | 55 | 50 | 43 | 44 | 16 | 12 |
| 4P LOSS WILD-TYPE | 24 | 17 | 19 | 16 | 14 | 16 |
Figure S238. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S239. Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 4P LOSS MUTATED | 69 | 119 | 84 | 42 |
| 4P LOSS WILD-TYPE | 37 | 31 | 75 | 41 |
Figure S239. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S240. Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 4P LOSS MUTATED | 98 | 151 | 65 |
| 4P LOSS WILD-TYPE | 80 | 38 | 66 |
Figure S240. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S241. Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 4P LOSS MUTATED | 135 | 57 | 52 | 57 |
| 4P LOSS WILD-TYPE | 49 | 30 | 72 | 23 |
Figure S241. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0492 (Fisher's exact test), Q value = 0.11
Table S242. Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 4P LOSS MUTATED | 62 | 79 | 126 | 34 |
| 4P LOSS WILD-TYPE | 27 | 39 | 73 | 35 |
Figure S242. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 6e-04
Table S243. Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 4P LOSS MUTATED | 34 | 81 | 26 | 68 |
| 4P LOSS WILD-TYPE | 27 | 34 | 40 | 24 |
Figure S243. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00078
Table S244. Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 4P LOSS MUTATED | 15 | 136 | 58 |
| 4P LOSS WILD-TYPE | 22 | 52 | 51 |
Figure S244. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00176 (Fisher's exact test), Q value = 0.009
Table S245. Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 4Q LOSS MUTATED | 26 | 37 | 11 | 19 |
| 4Q LOSS WILD-TYPE | 15 | 13 | 23 | 10 |
Figure S245. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00256 (Fisher's exact test), Q value = 0.012
Table S246. Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 4Q LOSS MUTATED | 31 | 41 | 21 |
| 4Q LOSS WILD-TYPE | 16 | 15 | 30 |
Figure S246. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S247. Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 4Q LOSS MUTATED | 29 | 47 | 10 | 41 | 136 | 34 |
| 4Q LOSS WILD-TYPE | 14 | 68 | 19 | 46 | 33 | 24 |
Figure S247. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00066 (Fisher's exact test), Q value = 0.004
Table S248. Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 4Q LOSS MUTATED | 51 | 69 | 39 | 59 |
| 4Q LOSS WILD-TYPE | 39 | 26 | 18 | 66 |
Figure S248. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S249. Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 4Q LOSS MUTATED | 62 | 112 | 86 | 36 |
| 4Q LOSS WILD-TYPE | 44 | 38 | 73 | 47 |
Figure S249. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00039 (Fisher's exact test), Q value = 0.0027
Table S250. Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 4Q LOSS MUTATED | 97 | 133 | 66 |
| 4Q LOSS WILD-TYPE | 81 | 56 | 65 |
Figure S250. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S251. Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 4Q LOSS MUTATED | 124 | 52 | 49 | 58 |
| 4Q LOSS WILD-TYPE | 60 | 35 | 75 | 22 |
Figure S251. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00066 (Fisher's exact test), Q value = 0.004
Table S252. Gene #49: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 4Q LOSS MUTATED | 33 | 71 | 26 | 66 |
| 4Q LOSS WILD-TYPE | 28 | 44 | 40 | 26 |
Figure S252. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00815 (Fisher's exact test), Q value = 0.029
Table S253. Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 4Q LOSS MUTATED | 19 | 124 | 53 |
| 4Q LOSS WILD-TYPE | 18 | 64 | 56 |
Figure S253. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S254. Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 5P LOSS MUTATED | 11 | 2 | 8 | 21 | 33 | 4 |
| 5P LOSS WILD-TYPE | 32 | 113 | 21 | 66 | 136 | 54 |
Figure S254. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00038 (Fisher's exact test), Q value = 0.0027
Table S255. Gene #50: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 5P LOSS MUTATED | 19 | 20 | 6 | 6 |
| 5P LOSS WILD-TYPE | 71 | 75 | 51 | 119 |
Figure S255. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0234 (Fisher's exact test), Q value = 0.067
Table S256. Gene #50: '5p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 79 | 67 | 62 | 60 | 30 | 28 |
| 5P LOSS MUTATED | 6 | 13 | 10 | 17 | 4 | 2 |
| 5P LOSS WILD-TYPE | 73 | 54 | 52 | 43 | 26 | 26 |
Figure S256. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0375 (Fisher's exact test), Q value = 0.091
Table S257. Gene #51: '5q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 5Q LOSS MUTATED | 22 | 40 | 29 |
| 5Q LOSS WILD-TYPE | 25 | 16 | 22 |
Figure S257. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S258. Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 5Q LOSS MUTATED | 25 | 43 | 19 | 58 | 113 | 32 |
| 5Q LOSS WILD-TYPE | 18 | 72 | 10 | 29 | 56 | 26 |
Figure S258. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0045 (Fisher's exact test), Q value = 0.019
Table S259. Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 5Q LOSS MUTATED | 58 | 63 | 31 | 56 |
| 5Q LOSS WILD-TYPE | 32 | 32 | 26 | 69 |
Figure S259. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00985 (Fisher's exact test), Q value = 0.034
Table S260. Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 5Q LOSS MUTATED | 57 | 103 | 86 | 41 |
| 5Q LOSS WILD-TYPE | 49 | 47 | 73 | 42 |
Figure S260. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 8e-04 (Fisher's exact test), Q value = 0.0046
Table S261. Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 5Q LOSS MUTATED | 90 | 129 | 68 |
| 5Q LOSS WILD-TYPE | 88 | 60 | 63 |
Figure S261. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0309 (Fisher's exact test), Q value = 0.08
Table S262. Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 5Q LOSS MUTATED | 110 | 57 | 58 | 49 |
| 5Q LOSS WILD-TYPE | 74 | 30 | 66 | 31 |
Figure S262. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0444 (Fisher's exact test), Q value = 0.1
Table S263. Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 5Q LOSS MUTATED | 55 | 70 | 120 | 29 |
| 5Q LOSS WILD-TYPE | 34 | 48 | 79 | 40 |
Figure S263. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00356 (Fisher's exact test), Q value = 0.016
Table S264. Gene #51: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 5Q LOSS MUTATED | 31 | 81 | 30 | 50 |
| 5Q LOSS WILD-TYPE | 30 | 34 | 36 | 42 |
Figure S264. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.028 (Fisher's exact test), Q value = 0.075
Table S265. Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 6P LOSS MUTATED | 5 | 18 | 6 | 4 |
| 6P LOSS WILD-TYPE | 36 | 32 | 28 | 25 |
Figure S265. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00732 (Fisher's exact test), Q value = 0.027
Table S266. Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 6P LOSS MUTATED | 6 | 20 | 7 |
| 6P LOSS WILD-TYPE | 41 | 36 | 44 |
Figure S266. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00073 (Fisher's exact test), Q value = 0.0043
Table S267. Gene #52: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 6P LOSS MUTATED | 13 | 22 | 9 | 11 | 53 | 6 |
| 6P LOSS WILD-TYPE | 30 | 93 | 20 | 76 | 116 | 52 |
Figure S267. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00051 (Fisher's exact test), Q value = 0.0033
Table S268. Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 6P LOSS MUTATED | 15 | 37 | 14 | 20 |
| 6P LOSS WILD-TYPE | 75 | 58 | 43 | 105 |
Figure S268. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S269. Gene #52: '6p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 6P LOSS MUTATED | 19 | 58 | 20 | 16 |
| 6P LOSS WILD-TYPE | 87 | 92 | 139 | 67 |
Figure S269. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S270. Gene #52: '6p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 6P LOSS MUTATED | 29 | 68 | 16 |
| 6P LOSS WILD-TYPE | 149 | 121 | 115 |
Figure S270. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0391 (Fisher's exact test), Q value = 0.094
Table S271. Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 6P LOSS MUTATED | 30 | 28 | 38 | 12 |
| 6P LOSS WILD-TYPE | 59 | 90 | 161 | 57 |
Figure S271. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0317 (Fisher's exact test), Q value = 0.081
Table S272. Gene #52: '6p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 6P LOSS MUTATED | 11 | 25 | 9 | 30 |
| 6P LOSS WILD-TYPE | 50 | 90 | 57 | 62 |
Figure S272. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00429 (Fisher's exact test), Q value = 0.018
Table S273. Gene #53: '6q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 6Q LOSS MUTATED | 6 | 21 | 5 | 4 |
| 6Q LOSS WILD-TYPE | 35 | 29 | 29 | 25 |
Figure S273. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00043 (Fisher's exact test), Q value = 0.003
Table S274. Gene #53: '6q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 6Q LOSS MUTATED | 8 | 23 | 5 |
| 6Q LOSS WILD-TYPE | 39 | 33 | 46 |
Figure S274. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0384 (Fisher's exact test), Q value = 0.093
Table S275. Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 6Q LOSS MUTATED | 15 | 21 | 7 | 14 | 48 | 9 |
| 6Q LOSS WILD-TYPE | 28 | 94 | 22 | 73 | 121 | 49 |
Figure S275. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0365 (Fisher's exact test), Q value = 0.09
Table S276. Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 6Q LOSS MUTATED | 18 | 30 | 17 | 21 |
| 6Q LOSS WILD-TYPE | 72 | 65 | 40 | 104 |
Figure S276. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00038 (Fisher's exact test), Q value = 0.0027
Table S277. Gene #53: '6q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 6Q LOSS MUTATED | 19 | 52 | 24 | 18 |
| 6Q LOSS WILD-TYPE | 87 | 98 | 135 | 65 |
Figure S277. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00795 (Fisher's exact test), Q value = 0.029
Table S278. Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 6Q LOSS MUTATED | 34 | 57 | 22 |
| 6Q LOSS WILD-TYPE | 144 | 132 | 109 |
Figure S278. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00072 (Fisher's exact test), Q value = 0.0042
Table S279. Gene #54: '7p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 7P LOSS MUTATED | 9 | 3 | 4 | 13 | 19 | 12 |
| 7P LOSS WILD-TYPE | 34 | 112 | 25 | 74 | 150 | 46 |
Figure S279. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0285 (Fisher's exact test), Q value = 0.076
Table S280. Gene #54: '7p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 7P LOSS MUTATED | 10 | 8 | 14 | 12 |
| 7P LOSS WILD-TYPE | 80 | 87 | 43 | 113 |
Figure S280. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.024 (Fisher's exact test), Q value = 0.068
Table S281. Gene #54: '7p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 7P LOSS MUTATED | 32 | 9 | 8 | 7 |
| 7P LOSS WILD-TYPE | 152 | 78 | 116 | 73 |
Figure S281. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00573 (Fisher's exact test), Q value = 0.022
Table S282. Gene #54: '7p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 7P LOSS MUTATED | 4 | 12 | 35 | 5 |
| 7P LOSS WILD-TYPE | 85 | 106 | 164 | 64 |
Figure S282. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.0011
Table S283. Gene #55: '7q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 7Q LOSS MUTATED | 10 | 6 | 30 | 4 |
| 7Q LOSS WILD-TYPE | 96 | 144 | 129 | 79 |
Figure S283. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00049 (Fisher's exact test), Q value = 0.0032
Table S284. Gene #55: '7q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 7Q LOSS MUTATED | 17 | 9 | 24 |
| 7Q LOSS WILD-TYPE | 161 | 180 | 107 |
Figure S284. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0404 (Fisher's exact test), Q value = 0.096
Table S285. Gene #55: '7q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 7Q LOSS MUTATED | 4 | 14 | 26 | 3 |
| 7Q LOSS WILD-TYPE | 85 | 104 | 173 | 66 |
Figure S285. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0141 (Fisher's exact test), Q value = 0.046
Table S286. Gene #55: '7q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 7Q LOSS MUTATED | 5 | 25 | 4 |
| 7Q LOSS WILD-TYPE | 32 | 163 | 105 |
Figure S286. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0131 (Fisher's exact test), Q value = 0.043
Table S287. Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 8P LOSS MUTATED | 25 | 39 | 17 | 44 | 90 | 28 |
| 8P LOSS WILD-TYPE | 18 | 76 | 12 | 43 | 79 | 30 |
Figure S287. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.045
Table S288. Gene #56: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 8P LOSS MUTATED | 47 | 55 | 33 | 48 |
| 8P LOSS WILD-TYPE | 43 | 40 | 24 | 77 |
Figure S288. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0333 (Fisher's exact test), Q value = 0.084
Table S289. Gene #56: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 8P LOSS MUTATED | 100 | 44 | 47 | 42 |
| 8P LOSS WILD-TYPE | 84 | 43 | 77 | 38 |
Figure S289. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.024 (Fisher's exact test), Q value = 0.068
Table S290. Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 8P LOSS MUTATED | 48 | 68 | 92 | 25 |
| 8P LOSS WILD-TYPE | 41 | 50 | 107 | 44 |
Figure S290. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00861 (Fisher's exact test), Q value = 0.031
Table S291. Gene #56: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 8P LOSS MUTATED | 37 | 53 | 22 | 51 |
| 8P LOSS WILD-TYPE | 24 | 62 | 44 | 41 |
Figure S291. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0244 (Fisher's exact test), Q value = 0.068
Table S292. Gene #57: '8q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 8Q LOSS MUTATED | 11 | 28 | 15 |
| 8Q LOSS WILD-TYPE | 167 | 161 | 116 |
Figure S292. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0368 (Fisher's exact test), Q value = 0.09
Table S293. Gene #57: '8q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 8Q LOSS MUTATED | 28 | 7 | 7 | 11 |
| 8Q LOSS WILD-TYPE | 156 | 80 | 117 | 69 |
Figure S293. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0237 (Fisher's exact test), Q value = 0.067
Table S294. Gene #58: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 9P LOSS MUTATED | 34 | 27 | 20 | 18 |
| 9P LOSS WILD-TYPE | 7 | 23 | 14 | 11 |
Figure S294. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0026 (Fisher's exact test), Q value = 0.012
Table S295. Gene #58: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 9P LOSS MUTATED | 39 | 29 | 31 |
| 9P LOSS WILD-TYPE | 8 | 27 | 20 |
Figure S295. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S296. Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 9P LOSS MUTATED | 29 | 51 | 26 | 76 | 91 | 42 |
| 9P LOSS WILD-TYPE | 14 | 64 | 3 | 11 | 78 | 16 |
Figure S296. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00172 (Fisher's exact test), Q value = 0.0089
Table S297. Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 9P LOSS MUTATED | 71 | 52 | 34 | 72 |
| 9P LOSS WILD-TYPE | 19 | 43 | 23 | 53 |
Figure S297. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S298. Gene #58: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 9P LOSS MUTATED | 83 | 75 | 112 | 42 |
| 9P LOSS WILD-TYPE | 23 | 75 | 47 | 41 |
Figure S298. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00032
Table S299. Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 9P LOSS MUTATED | 134 | 97 | 81 |
| 9P LOSS WILD-TYPE | 44 | 92 | 50 |
Figure S299. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00807 (Fisher's exact test), Q value = 0.029
Table S300. Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 9P LOSS MUTATED | 122 | 63 | 73 | 39 |
| 9P LOSS WILD-TYPE | 62 | 24 | 51 | 41 |
Figure S300. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00046 (Fisher's exact test), Q value = 0.0031
Table S301. Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 9P LOSS MUTATED | 45 | 75 | 143 | 34 |
| 9P LOSS WILD-TYPE | 44 | 43 | 56 | 35 |
Figure S301. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S302. Gene #58: '9p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 9P LOSS MUTATED | 44 | 85 | 26 | 53 |
| 9P LOSS WILD-TYPE | 17 | 30 | 40 | 39 |
Figure S302. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0155 (Fisher's exact test), Q value = 0.048
Table S303. Gene #58: '9p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 9P LOSS MUTATED | 29 | 121 | 58 |
| 9P LOSS WILD-TYPE | 8 | 67 | 51 |
Figure S303. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S304. Gene #59: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 9Q LOSS MUTATED | 27 | 10 | 22 | 16 |
| 9Q LOSS WILD-TYPE | 14 | 40 | 12 | 13 |
Figure S304. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S305. Gene #59: '9q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 9Q LOSS MUTATED | 31 | 12 | 32 |
| 9Q LOSS WILD-TYPE | 16 | 44 | 19 |
Figure S305. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S306. Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 9Q LOSS MUTATED | 28 | 50 | 23 | 61 | 44 | 41 |
| 9Q LOSS WILD-TYPE | 15 | 65 | 6 | 26 | 125 | 17 |
Figure S306. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S307. Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 9Q LOSS MUTATED | 67 | 25 | 24 | 66 |
| 9Q LOSS WILD-TYPE | 23 | 70 | 33 | 59 |
Figure S307. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00071 (Fisher's exact test), Q value = 0.0042
Table S308. Gene #59: '9q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 9Q LOSS MUTATED | 51 | 67 | 28 | 15 |
| 9Q LOSS WILD-TYPE | 54 | 42 | 58 | 11 |
Figure S308. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00169 (Fisher's exact test), Q value = 0.0088
Table S309. Gene #59: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 79 | 67 | 62 | 60 | 30 | 28 |
| 9Q LOSS MUTATED | 31 | 23 | 42 | 33 | 16 | 16 |
| 9Q LOSS WILD-TYPE | 48 | 44 | 20 | 27 | 14 | 12 |
Figure S309. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S310. Gene #59: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 9Q LOSS MUTATED | 73 | 29 | 100 | 43 |
| 9Q LOSS WILD-TYPE | 33 | 121 | 59 | 40 |
Figure S310. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S311. Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 9Q LOSS MUTATED | 126 | 43 | 76 |
| 9Q LOSS WILD-TYPE | 52 | 146 | 55 |
Figure S311. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S312. Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 9Q LOSS MUTATED | 86 | 58 | 70 | 18 |
| 9Q LOSS WILD-TYPE | 98 | 29 | 54 | 62 |
Figure S312. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S313. Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 9Q LOSS MUTATED | 18 | 54 | 129 | 31 |
| 9Q LOSS WILD-TYPE | 71 | 64 | 70 | 38 |
Figure S313. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00264 (Fisher's exact test), Q value = 0.012
Table S314. Gene #59: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 9Q LOSS MUTATED | 42 | 58 | 24 | 43 |
| 9Q LOSS WILD-TYPE | 19 | 57 | 42 | 49 |
Figure S314. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0011 (Fisher's exact test), Q value = 0.0059
Table S315. Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 9Q LOSS MUTATED | 29 | 86 | 52 |
| 9Q LOSS WILD-TYPE | 8 | 102 | 57 |
Figure S315. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S316. Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 10P LOSS MUTATED | 19 | 32 | 16 | 28 | 98 | 22 |
| 10P LOSS WILD-TYPE | 24 | 83 | 13 | 59 | 71 | 36 |
Figure S316. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0016
Table S317. Gene #60: '10p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 10P LOSS MUTATED | 35 | 53 | 31 | 36 |
| 10P LOSS WILD-TYPE | 55 | 42 | 26 | 89 |
Figure S317. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00749 (Fisher's exact test), Q value = 0.028
Table S318. Gene #60: '10p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 10P LOSS MUTATED | 33 | 39 | 42 | 16 |
| 10P LOSS WILD-TYPE | 72 | 70 | 44 | 10 |
Figure S318. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S319. Gene #60: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 10P LOSS MUTATED | 36 | 91 | 60 | 27 |
| 10P LOSS WILD-TYPE | 70 | 59 | 99 | 56 |
Figure S319. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.0012
Table S320. Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 10P LOSS MUTATED | 67 | 104 | 43 |
| 10P LOSS WILD-TYPE | 111 | 85 | 88 |
Figure S320. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00011 (Fisher's exact test), Q value = 0.001
Table S321. Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 10P LOSS MUTATED | 88 | 37 | 34 | 46 |
| 10P LOSS WILD-TYPE | 96 | 50 | 90 | 34 |
Figure S321. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S322. Gene #60: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 10P LOSS MUTATED | 58 | 41 | 91 | 15 |
| 10P LOSS WILD-TYPE | 31 | 77 | 108 | 54 |
Figure S322. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00336 (Fisher's exact test), Q value = 0.015
Table S323. Gene #60: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 10P LOSS MUTATED | 24 | 55 | 15 | 44 |
| 10P LOSS WILD-TYPE | 37 | 60 | 51 | 48 |
Figure S323. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00464 (Fisher's exact test), Q value = 0.019
Table S324. Gene #61: '10q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 10Q LOSS MUTATED | 13 | 32 | 13 | 9 |
| 10Q LOSS WILD-TYPE | 28 | 18 | 21 | 20 |
Figure S324. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0016
Table S325. Gene #61: '10q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 10Q LOSS MUTATED | 12 | 36 | 19 |
| 10Q LOSS WILD-TYPE | 35 | 20 | 32 |
Figure S325. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S326. Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 10Q LOSS MUTATED | 22 | 36 | 13 | 31 | 108 | 19 |
| 10Q LOSS WILD-TYPE | 21 | 79 | 16 | 56 | 61 | 39 |
Figure S326. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00078
Table S327. Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 10Q LOSS MUTATED | 37 | 59 | 33 | 41 |
| 10Q LOSS WILD-TYPE | 53 | 36 | 24 | 84 |
Figure S327. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00687 (Fisher's exact test), Q value = 0.026
Table S328. Gene #61: '10q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 10Q LOSS MUTATED | 40 | 41 | 50 | 15 |
| 10Q LOSS WILD-TYPE | 65 | 68 | 36 | 11 |
Figure S328. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S329. Gene #61: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 10Q LOSS MUTATED | 41 | 101 | 60 | 26 |
| 10Q LOSS WILD-TYPE | 65 | 49 | 99 | 57 |
Figure S329. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S330. Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 10Q LOSS MUTATED | 69 | 118 | 41 |
| 10Q LOSS WILD-TYPE | 109 | 71 | 90 |
Figure S330. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 5e-04 (Fisher's exact test), Q value = 0.0032
Table S331. Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 10Q LOSS MUTATED | 87 | 42 | 40 | 49 |
| 10Q LOSS WILD-TYPE | 97 | 45 | 84 | 31 |
Figure S331. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S332. Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 10Q LOSS MUTATED | 61 | 43 | 96 | 18 |
| 10Q LOSS WILD-TYPE | 28 | 75 | 103 | 51 |
Figure S332. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0031
Table S333. Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 10Q LOSS MUTATED | 24 | 63 | 17 | 49 |
| 10Q LOSS WILD-TYPE | 37 | 52 | 49 | 43 |
Figure S333. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00204 (Fisher's exact test), Q value = 0.01
Table S334. Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 11P LOSS MUTATED | 21 | 22 | 11 | 31 | 59 | 25 |
| 11P LOSS WILD-TYPE | 22 | 93 | 18 | 56 | 110 | 33 |
Figure S334. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0103 (Fisher's exact test), Q value = 0.035
Table S335. Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 11P LOSS MUTATED | 39 | 32 | 21 | 28 |
| 11P LOSS WILD-TYPE | 51 | 63 | 36 | 97 |
Figure S335. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00938 (Fisher's exact test), Q value = 0.033
Table S336. Gene #62: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 11P LOSS MUTATED | 78 | 27 | 35 | 19 |
| 11P LOSS WILD-TYPE | 106 | 60 | 89 | 61 |
Figure S336. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0393 (Fisher's exact test), Q value = 0.094
Table S337. Gene #62: '11p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 11P LOSS MUTATED | 23 | 37 | 13 | 37 |
| 11P LOSS WILD-TYPE | 38 | 78 | 53 | 55 |
Figure S337. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0161 (Fisher's exact test), Q value = 0.05
Table S338. Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 11Q LOSS MUTATED | 11 | 22 | 11 | 19 | 58 | 22 |
| 11Q LOSS WILD-TYPE | 32 | 93 | 18 | 68 | 111 | 36 |
Figure S338. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0143 (Fisher's exact test), Q value = 0.046
Table S339. Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 11Q LOSS MUTATED | 32 | 28 | 22 | 24 |
| 11Q LOSS WILD-TYPE | 58 | 67 | 35 | 101 |
Figure S339. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.034 (Fisher's exact test), Q value = 0.085
Table S340. Gene #64: '12p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 12P LOSS MUTATED | 0 | 3 | 3 | 5 |
| 12P LOSS WILD-TYPE | 41 | 47 | 31 | 24 |
Figure S340. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0056 (Fisher's exact test), Q value = 0.022
Table S341. Gene #64: '12p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 12P LOSS MUTATED | 0 | 3 | 8 |
| 12P LOSS WILD-TYPE | 47 | 53 | 43 |
Figure S341. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0287 (Fisher's exact test), Q value = 0.076
Table S342. Gene #65: '12q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 12Q LOSS MUTATED | 12 | 15 | 8 | 9 |
| 12Q LOSS WILD-TYPE | 172 | 72 | 116 | 71 |
Figure S342. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00023
Table S343. Gene #66: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 13Q LOSS MUTATED | 33 | 57 | 10 | 68 | 106 | 37 |
| 13Q LOSS WILD-TYPE | 10 | 58 | 19 | 19 | 63 | 21 |
Figure S343. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0291 (Fisher's exact test), Q value = 0.076
Table S344. Gene #66: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 13Q LOSS MUTATED | 57 | 68 | 34 | 65 |
| 13Q LOSS WILD-TYPE | 33 | 27 | 23 | 60 |
Figure S344. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0276 (Fisher's exact test), Q value = 0.074
Table S345. Gene #66: '13q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 13Q LOSS MUTATED | 36 | 75 | 31 | 64 |
| 13Q LOSS WILD-TYPE | 25 | 40 | 35 | 28 |
Figure S345. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S346. Gene #67: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 14Q LOSS MUTATED | 1 | 21 | 11 | 14 |
| 14Q LOSS WILD-TYPE | 40 | 29 | 23 | 15 |
Figure S346. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.0016
Table S347. Gene #67: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 14Q LOSS MUTATED | 4 | 23 | 20 |
| 14Q LOSS WILD-TYPE | 43 | 33 | 31 |
Figure S347. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S348. Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 14Q LOSS MUTATED | 2 | 28 | 3 | 34 | 74 | 26 |
| 14Q LOSS WILD-TYPE | 41 | 87 | 26 | 53 | 95 | 32 |
Figure S348. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0399 (Fisher's exact test), Q value = 0.095
Table S349. Gene #67: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 14Q LOSS MUTATED | 26 | 34 | 29 | 39 |
| 14Q LOSS WILD-TYPE | 64 | 61 | 28 | 86 |
Figure S349. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00291 (Fisher's exact test), Q value = 0.013
Table S350. Gene #67: '14q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 14Q LOSS MUTATED | 42 | 26 | 41 | 7 |
| 14Q LOSS WILD-TYPE | 63 | 83 | 45 | 19 |
Figure S350. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S351. Gene #67: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 14Q LOSS MUTATED | 15 | 63 | 70 | 17 |
| 14Q LOSS WILD-TYPE | 91 | 87 | 89 | 66 |
Figure S351. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S352. Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 14Q LOSS MUTATED | 28 | 76 | 61 |
| 14Q LOSS WILD-TYPE | 150 | 113 | 70 |
Figure S352. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00028 (Fisher's exact test), Q value = 0.0021
Table S353. Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 14Q LOSS MUTATED | 57 | 29 | 29 | 42 |
| 14Q LOSS WILD-TYPE | 127 | 58 | 95 | 38 |
Figure S353. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S354. Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 14Q LOSS MUTATED | 51 | 35 | 58 | 13 |
| 14Q LOSS WILD-TYPE | 38 | 83 | 141 | 56 |
Figure S354. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00067 (Fisher's exact test), Q value = 0.004
Table S355. Gene #67: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 14Q LOSS MUTATED | 6 | 81 | 29 |
| 14Q LOSS WILD-TYPE | 31 | 107 | 80 |
Figure S355. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S356. Gene #68: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 15Q LOSS MUTATED | 26 | 33 | 6 | 8 | 44 | 24 |
| 15Q LOSS WILD-TYPE | 17 | 82 | 23 | 79 | 125 | 34 |
Figure S356. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0464 (Fisher's exact test), Q value = 0.11
Table S357. Gene #68: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 15Q LOSS MUTATED | 31 | 35 | 57 | 18 |
| 15Q LOSS WILD-TYPE | 75 | 115 | 102 | 65 |
Figure S357. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00318 (Fisher's exact test), Q value = 0.014
Table S358. Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 15Q LOSS MUTATED | 64 | 29 | 25 | 14 |
| 15Q LOSS WILD-TYPE | 120 | 58 | 99 | 66 |
Figure S358. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0234 (Fisher's exact test), Q value = 0.067
Table S359. Gene #68: '15q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 15Q LOSS MUTATED | 16 | 33 | 9 | 32 |
| 15Q LOSS WILD-TYPE | 45 | 82 | 57 | 60 |
Figure S359. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00459 (Fisher's exact test), Q value = 0.019
Table S360. Gene #69: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 16P LOSS MUTATED | 11 | 24 | 9 | 29 | 61 | 29 |
| 16P LOSS WILD-TYPE | 32 | 91 | 20 | 58 | 108 | 29 |
Figure S360. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0357 (Fisher's exact test), Q value = 0.088
Table S361. Gene #69: '16p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 16P LOSS MUTATED | 37 | 28 | 25 | 33 |
| 16P LOSS WILD-TYPE | 53 | 67 | 32 | 92 |
Figure S361. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0218 (Fisher's exact test), Q value = 0.064
Table S362. Gene #69: '16p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 16P LOSS MUTATED | 33 | 37 | 37 | 3 |
| 16P LOSS WILD-TYPE | 72 | 72 | 49 | 23 |
Figure S362. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.015 (Fisher's exact test), Q value = 0.047
Table S363. Gene #69: '16p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 16P LOSS MUTATED | 65 | 37 | 28 | 25 |
| 16P LOSS WILD-TYPE | 119 | 50 | 96 | 55 |
Figure S363. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00206 (Fisher's exact test), Q value = 0.01
Table S364. Gene #69: '16p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 16P LOSS MUTATED | 21 | 45 | 10 | 37 |
| 16P LOSS WILD-TYPE | 40 | 70 | 56 | 55 |
Figure S364. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0267 (Fisher's exact test), Q value = 0.073
Table S365. Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 16Q LOSS MUTATED | 14 | 28 | 12 | 32 | 74 | 24 |
| 16Q LOSS WILD-TYPE | 29 | 87 | 17 | 55 | 95 | 34 |
Figure S365. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0022 (Fisher's exact test), Q value = 0.011
Table S366. Gene #70: '16q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 105 | 109 | 86 | 26 |
| 16Q LOSS MUTATED | 40 | 34 | 46 | 5 |
| 16Q LOSS WILD-TYPE | 65 | 75 | 40 | 21 |
Figure S366. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0274 (Fisher's exact test), Q value = 0.074
Table S367. Gene #70: '16q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 16Q LOSS MUTATED | 33 | 63 | 65 | 21 |
| 16Q LOSS WILD-TYPE | 73 | 87 | 94 | 62 |
Figure S367. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0222 (Fisher's exact test), Q value = 0.064
Table S368. Gene #70: '16q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 16Q LOSS MUTATED | 51 | 78 | 53 |
| 16Q LOSS WILD-TYPE | 127 | 111 | 78 |
Figure S368. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00259 (Fisher's exact test), Q value = 0.012
Table S369. Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 16Q LOSS MUTATED | 68 | 43 | 31 | 33 |
| 16Q LOSS WILD-TYPE | 116 | 44 | 93 | 47 |
Figure S369. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0255 (Fisher's exact test), Q value = 0.07
Table S370. Gene #70: '16q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 16Q LOSS MUTATED | 19 | 52 | 16 | 37 |
| 16Q LOSS WILD-TYPE | 42 | 63 | 50 | 55 |
Figure S370. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00531 (Fisher's exact test), Q value = 0.021
Table S371. Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 16Q LOSS MUTATED | 9 | 84 | 31 |
| 16Q LOSS WILD-TYPE | 28 | 104 | 78 |
Figure S371. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0202 (Fisher's exact test), Q value = 0.06
Table S372. Gene #71: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 17P LOSS MUTATED | 32 | 25 | 22 | 14 |
| 17P LOSS WILD-TYPE | 9 | 25 | 12 | 15 |
Figure S372. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 6e-04
Table S373. Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 17P LOSS MUTATED | 31 | 48 | 16 | 65 | 95 | 37 |
| 17P LOSS WILD-TYPE | 12 | 67 | 13 | 22 | 74 | 21 |
Figure S373. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0114 (Fisher's exact test), Q value = 0.039
Table S374. Gene #71: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 17P LOSS MUTATED | 60 | 46 | 38 | 62 |
| 17P LOSS WILD-TYPE | 30 | 49 | 19 | 63 |
Figure S374. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0327 (Fisher's exact test), Q value = 0.083
Table S375. Gene #71: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 79 | 67 | 62 | 60 | 30 | 28 |
| 17P LOSS MUTATED | 48 | 46 | 41 | 29 | 15 | 11 |
| 17P LOSS WILD-TYPE | 31 | 21 | 21 | 31 | 15 | 17 |
Figure S375. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00404 (Fisher's exact test), Q value = 0.017
Table S376. Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 17P LOSS MUTATED | 72 | 71 | 101 | 47 |
| 17P LOSS WILD-TYPE | 34 | 79 | 58 | 36 |
Figure S376. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00098 (Fisher's exact test), Q value = 0.0054
Table S377. Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 17P LOSS MUTATED | 122 | 94 | 75 |
| 17P LOSS WILD-TYPE | 56 | 95 | 56 |
Figure S377. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00591 (Fisher's exact test), Q value = 0.023
Table S378. Gene #71: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 17P LOSS MUTATED | 121 | 57 | 65 | 37 |
| 17P LOSS WILD-TYPE | 63 | 30 | 59 | 43 |
Figure S378. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00243 (Fisher's exact test), Q value = 0.012
Table S379. Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 17P LOSS MUTATED | 42 | 75 | 131 | 32 |
| 17P LOSS WILD-TYPE | 47 | 43 | 68 | 37 |
Figure S379. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0368 (Fisher's exact test), Q value = 0.09
Table S380. Gene #71: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| 17P LOSS MUTATED | 25 | 117 | 53 |
| 17P LOSS WILD-TYPE | 12 | 71 | 56 |
Figure S380. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0135 (Fisher's exact test), Q value = 0.044
Table S381. Gene #72: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 17Q LOSS MUTATED | 13 | 3 | 6 | 4 |
| 17Q LOSS WILD-TYPE | 28 | 47 | 28 | 25 |
Figure S381. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00608 (Fisher's exact test), Q value = 0.024
Table S382. Gene #72: '17q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 17Q LOSS MUTATED | 13 | 3 | 10 |
| 17Q LOSS WILD-TYPE | 34 | 53 | 41 |
Figure S382. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00024 (Fisher's exact test), Q value = 0.0018
Table S383. Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 17Q LOSS MUTATED | 14 | 23 | 9 | 20 | 14 | 11 |
| 17Q LOSS WILD-TYPE | 29 | 92 | 20 | 67 | 155 | 47 |
Figure S383. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00905 (Fisher's exact test), Q value = 0.032
Table S384. Gene #72: '17q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 17Q LOSS MUTATED | 20 | 10 | 6 | 32 |
| 17Q LOSS WILD-TYPE | 70 | 85 | 51 | 93 |
Figure S384. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0016
Table S385. Gene #72: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 17Q LOSS MUTATED | 30 | 12 | 31 | 18 |
| 17Q LOSS WILD-TYPE | 76 | 138 | 128 | 65 |
Figure S385. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S386. Gene #72: '17q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 17Q LOSS MUTATED | 56 | 16 | 19 |
| 17Q LOSS WILD-TYPE | 122 | 173 | 112 |
Figure S386. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.01 (Fisher's exact test), Q value = 0.035
Table S387. Gene #72: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 17Q LOSS MUTATED | 25 | 17 | 35 | 11 |
| 17Q LOSS WILD-TYPE | 159 | 70 | 89 | 69 |
Figure S387. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0073 (Fisher's exact test), Q value = 0.027
Table S388. Gene #72: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 17Q LOSS MUTATED | 8 | 17 | 45 | 18 |
| 17Q LOSS WILD-TYPE | 81 | 101 | 154 | 51 |
Figure S388. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.029 (Fisher's exact test), Q value = 0.076
Table S389. Gene #73: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 18P LOSS MUTATED | 13 | 29 | 14 | 29 | 36 | 20 |
| 18P LOSS WILD-TYPE | 30 | 86 | 15 | 58 | 133 | 38 |
Figure S389. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0116 (Fisher's exact test), Q value = 0.039
Table S390. Gene #73: '18p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 18P LOSS MUTATED | 23 | 16 | 22 | 41 |
| 18P LOSS WILD-TYPE | 67 | 79 | 35 | 84 |
Figure S390. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0157 (Fisher's exact test), Q value = 0.049
Table S391. Gene #73: '18p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 18P LOSS MUTATED | 13 | 27 | 14 | 37 |
| 18P LOSS WILD-TYPE | 48 | 88 | 52 | 55 |
Figure S391. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0038 (Fisher's exact test), Q value = 0.016
Table S392. Gene #74: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 18Q LOSS MUTATED | 26 | 34 | 13 | 38 | 54 | 25 |
| 18Q LOSS WILD-TYPE | 17 | 81 | 16 | 49 | 115 | 33 |
Figure S392. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0463 (Fisher's exact test), Q value = 0.11
Table S393. Gene #74: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 18Q LOSS MUTATED | 36 | 27 | 29 | 50 |
| 18Q LOSS WILD-TYPE | 54 | 68 | 28 | 75 |
Figure S393. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0342 (Fisher's exact test), Q value = 0.085
Table S394. Gene #74: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 18Q LOSS MUTATED | 21 | 41 | 20 | 47 |
| 18Q LOSS WILD-TYPE | 40 | 74 | 46 | 45 |
Figure S394. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00032
Table S395. Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 19P LOSS MUTATED | 26 | 24 | 11 | 32 | 44 | 25 |
| 19P LOSS WILD-TYPE | 17 | 91 | 18 | 55 | 125 | 33 |
Figure S395. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0346 (Fisher's exact test), Q value = 0.085
Table S396. Gene #75: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 19P LOSS MUTATED | 36 | 35 | 58 | 32 |
| 19P LOSS WILD-TYPE | 70 | 115 | 101 | 51 |
Figure S396. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0164 (Fisher's exact test), Q value = 0.051
Table S397. Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 19P LOSS MUTATED | 60 | 48 | 53 |
| 19P LOSS WILD-TYPE | 118 | 141 | 78 |
Figure S397. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0451 (Fisher's exact test), Q value = 0.1
Table S398. Gene #75: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 19P LOSS MUTATED | 64 | 35 | 32 | 19 |
| 19P LOSS WILD-TYPE | 120 | 52 | 92 | 61 |
Figure S398. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.0013
Table S399. Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 19P LOSS MUTATED | 16 | 38 | 82 | 14 |
| 19P LOSS WILD-TYPE | 73 | 80 | 117 | 55 |
Figure S399. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00503 (Fisher's exact test), Q value = 0.02
Table S400. Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 19Q LOSS MUTATED | 15 | 12 | 9 | 22 | 40 | 12 |
| 19Q LOSS WILD-TYPE | 28 | 103 | 20 | 65 | 129 | 46 |
Figure S400. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0413 (Fisher's exact test), Q value = 0.098
Table S401. Gene #77: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 20P LOSS MUTATED | 14 | 5 | 3 | 7 |
| 20P LOSS WILD-TYPE | 76 | 90 | 54 | 118 |
Figure S401. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.03 (Fisher's exact test), Q value = 0.078
Table S402. Gene #77: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 20P LOSS MUTATED | 16 | 9 | 17 |
| 20P LOSS WILD-TYPE | 162 | 180 | 114 |
Figure S402. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0372 (Fisher's exact test), Q value = 0.091
Table S403. Gene #77: '20p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 20P LOSS MUTATED | 6 | 10 | 0 | 7 |
| 20P LOSS WILD-TYPE | 55 | 105 | 66 | 85 |
Figure S403. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.047 (Fisher's exact test), Q value = 0.11
Table S404. Gene #78: '20q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 20Q LOSS MUTATED | 1 | 10 | 3 | 2 |
| 20Q LOSS WILD-TYPE | 40 | 40 | 31 | 27 |
Figure S404. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00049 (Fisher's exact test), Q value = 0.0032
Table S405. Gene #78: '20q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 20Q LOSS MUTATED | 1 | 5 | 3 | 5 | 31 | 4 |
| 20Q LOSS WILD-TYPE | 42 | 110 | 26 | 82 | 138 | 54 |
Figure S405. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00047 (Fisher's exact test), Q value = 0.0031
Table S406. Gene #78: '20q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 20Q LOSS MUTATED | 6 | 28 | 12 | 3 |
| 20Q LOSS WILD-TYPE | 100 | 122 | 147 | 80 |
Figure S406. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00764 (Fisher's exact test), Q value = 0.028
Table S407. Gene #78: '20q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 20Q LOSS MUTATED | 11 | 29 | 9 |
| 20Q LOSS WILD-TYPE | 167 | 160 | 122 |
Figure S407. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00855 (Fisher's exact test), Q value = 0.031
Table S408. Gene #78: '20q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 20Q LOSS MUTATED | 26 | 11 | 4 | 8 |
| 20Q LOSS WILD-TYPE | 158 | 76 | 120 | 72 |
Figure S408. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S409. Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 21Q LOSS MUTATED | 24 | 40 | 21 | 37 | 108 | 34 |
| 21Q LOSS WILD-TYPE | 19 | 75 | 8 | 50 | 61 | 24 |
Figure S409. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00682 (Fisher's exact test), Q value = 0.026
Table S410. Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| 21Q LOSS MUTATED | 46 | 60 | 32 | 50 |
| 21Q LOSS WILD-TYPE | 44 | 35 | 25 | 75 |
Figure S410. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0339 (Fisher's exact test), Q value = 0.085
Table S411. Gene #79: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 21Q LOSS MUTATED | 50 | 92 | 85 | 36 |
| 21Q LOSS WILD-TYPE | 56 | 58 | 74 | 47 |
Figure S411. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.0023
Table S412. Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| 21Q LOSS MUTATED | 112 | 52 | 46 | 42 |
| 21Q LOSS WILD-TYPE | 72 | 35 | 78 | 38 |
Figure S412. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00057 (Fisher's exact test), Q value = 0.0036
Table S413. Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 21Q LOSS MUTATED | 51 | 64 | 116 | 21 |
| 21Q LOSS WILD-TYPE | 38 | 54 | 83 | 48 |
Figure S413. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0173 (Fisher's exact test), Q value = 0.053
Table S414. Gene #79: '21q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| 21Q LOSS MUTATED | 28 | 66 | 23 | 51 |
| 21Q LOSS WILD-TYPE | 33 | 49 | 43 | 41 |
Figure S414. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0234 (Fisher's exact test), Q value = 0.067
Table S415. Gene #80: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 41 | 50 | 34 | 29 |
| 22Q LOSS MUTATED | 7 | 6 | 8 | 12 |
| 22Q LOSS WILD-TYPE | 34 | 44 | 26 | 17 |
Figure S415. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0018 (Fisher's exact test), Q value = 0.0091
Table S416. Gene #80: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| 22Q LOSS MUTATED | 10 | 27 | 0 | 23 | 23 | 15 |
| 22Q LOSS WILD-TYPE | 33 | 88 | 29 | 64 | 146 | 43 |
Figure S416. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.001
Table S417. Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| 22Q LOSS MUTATED | 22 | 14 | 47 | 15 |
| 22Q LOSS WILD-TYPE | 84 | 136 | 112 | 68 |
Figure S417. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S418. Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 22Q LOSS MUTATED | 26 | 24 | 48 |
| 22Q LOSS WILD-TYPE | 152 | 165 | 83 |
Figure S418. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00914 (Fisher's exact test), Q value = 0.032
Table S419. Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 22Q LOSS MUTATED | 10 | 31 | 41 | 7 |
| 22Q LOSS WILD-TYPE | 79 | 87 | 158 | 62 |
Figure S419. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S420. Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| XP LOSS MUTATED | 9 | 13 | 10 | 33 | 67 | 13 |
| XP LOSS WILD-TYPE | 34 | 102 | 19 | 54 | 102 | 45 |
Figure S420. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S421. Gene #81: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| XP LOSS MUTATED | 34 | 36 | 20 | 14 |
| XP LOSS WILD-TYPE | 56 | 59 | 37 | 111 |
Figure S421. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00174 (Fisher's exact test), Q value = 0.009
Table S422. Gene #81: 'xp loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| XP LOSS MUTATED | 30 | 57 | 44 | 12 |
| XP LOSS WILD-TYPE | 76 | 93 | 115 | 71 |
Figure S422. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0267 (Fisher's exact test), Q value = 0.073
Table S423. Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| XP LOSS MUTATED | 47 | 67 | 29 |
| XP LOSS WILD-TYPE | 131 | 122 | 102 |
Figure S423. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00526 (Fisher's exact test), Q value = 0.021
Table S424. Gene #81: 'xp loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| XP LOSS MUTATED | 63 | 26 | 22 | 29 |
| XP LOSS WILD-TYPE | 121 | 61 | 102 | 51 |
Figure S424. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00157 (Fisher's exact test), Q value = 0.0083
Table S425. Gene #81: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| XP LOSS MUTATED | 35 | 40 | 56 | 9 |
| XP LOSS WILD-TYPE | 54 | 78 | 143 | 60 |
Figure S425. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00069 (Fisher's exact test), Q value = 0.0041
Table S426. Gene #81: 'xp loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| XP LOSS MUTATED | 13 | 44 | 8 | 29 |
| XP LOSS WILD-TYPE | 48 | 71 | 58 | 63 |
Figure S426. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0209 (Fisher's exact test), Q value = 0.061
Table S427. Gene #81: 'xp loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| XP LOSS MUTATED | 9 | 64 | 21 |
| XP LOSS WILD-TYPE | 28 | 124 | 88 |
Figure S427. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S428. Gene #82: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 43 | 115 | 29 | 87 | 169 | 58 |
| XQ LOSS MUTATED | 9 | 9 | 5 | 33 | 46 | 12 |
| XQ LOSS WILD-TYPE | 34 | 106 | 24 | 54 | 123 | 46 |
Figure S428. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S429. Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 90 | 95 | 57 | 125 |
| XQ LOSS MUTATED | 34 | 23 | 16 | 9 |
| XQ LOSS WILD-TYPE | 56 | 72 | 41 | 116 |
Figure S429. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00722 (Fisher's exact test), Q value = 0.027
Table S430. Gene #82: 'xq loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 106 | 150 | 159 | 83 |
| XQ LOSS MUTATED | 24 | 36 | 45 | 8 |
| XQ LOSS WILD-TYPE | 82 | 114 | 114 | 75 |
Figure S430. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.001
Table S431. Gene #82: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 87 | 124 | 80 |
| XQ LOSS MUTATED | 54 | 26 | 12 | 18 |
| XQ LOSS WILD-TYPE | 130 | 61 | 112 | 62 |
Figure S431. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.012 (Fisher's exact test), Q value = 0.04
Table S432. Gene #82: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| XQ LOSS MUTATED | 22 | 29 | 53 | 6 |
| XQ LOSS WILD-TYPE | 67 | 89 | 146 | 63 |
Figure S432. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00218 (Fisher's exact test), Q value = 0.011
Table S433. Gene #82: 'xq loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 61 | 115 | 66 | 92 |
| XQ LOSS MUTATED | 12 | 35 | 5 | 23 |
| XQ LOSS WILD-TYPE | 49 | 80 | 61 | 69 |
Figure S433. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00093 (Fisher's exact test), Q value = 0.0051
Table S434. Gene #82: 'xq loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 37 | 188 | 109 |
| XQ LOSS MUTATED | 9 | 54 | 12 |
| XQ LOSS WILD-TYPE | 28 | 134 | 97 |
Figure S434. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
-
Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/LUSC-TP/22533933/transformed.cor.cli.txt
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Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/LUSC-TP/22552638/LUSC-TP.transferedmergedcluster.txt
-
Number of patients = 501
-
Number of significantly arm-level cnvs = 82
-
Number of molecular subtypes = 12
-
Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.