Testing the association between 18249 genes and 15 clinical features across 223 samples, statistically thresholded by Q value < 0.05, 12 clinical features related to at least one genes.
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6 genes correlated to 'Time to Death'.
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UCN2|90226 , DKK1|22943 , IRX5|10265 , FAM189A2|9413 , CDH26|60437 , ...
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54 genes correlated to 'GENDER'.
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PRKY|5616 , XIST|7503 , ZFY|7544 , RPS4Y1|6192 , DDX3Y|8653 , ...
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2 genes correlated to 'KARNOFSKY.PERFORMANCE.SCORE'.
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PSMA5|5686 , PRPF8|10594
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16 genes correlated to 'HISTOLOGICAL.TYPE'.
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DPCR1|135656 , CDHR2|54825 , REG4|83998 , B3GALT5|10317 , ODF2L|57489 , ...
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7 genes correlated to 'PATHOLOGY.T'.
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FAM125B|89853 , APBB1|322 , MAL|4118 , PPIF|10105 , CADM3|57863 , ...
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2 genes correlated to 'PATHOLOGY.N'.
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FAM117A|81558 , RARS|5917
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25 genes correlated to 'PATHOLOGICSPREAD(M)'.
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AKAP5|9495 , MLL5|55904 , RNF187|149603 , MLST8|64223 , ZNF37B|100129482 , ...
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1 gene correlated to 'TUMOR.STAGE'.
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ST6GAL1|6480
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1 gene correlated to 'RADIATIONS.RADIATION.REGIMENINDICATION'.
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KCNU1|157855
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1 gene correlated to 'NUMBERPACKYEARSSMOKED'.
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LOC723809|723809
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1 gene correlated to 'STOPPEDSMOKINGYEAR'.
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GPR15|2838
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3 genes correlated to 'TOBACCOSMOKINGHISTORYINDICATOR'.
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GPR15|2838 , CASR|846 , RBM17|84991
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No genes correlated to 'AGE', 'NEOADJUVANT.THERAPY', and 'YEAROFTOBACCOSMOKINGONSET'.
Complete statistical result table is provided in Supplement Table 1
Table 1. Get Full Table This table shows the clinical features, statistical methods used, and the number of genes that are significantly associated with each clinical feature at Q value < 0.05.
| Clinical feature | Statistical test | Significant genes | Associated with | Associated with | ||
|---|---|---|---|---|---|---|
| Time to Death | Cox regression test | N=6 | shorter survival | N=3 | longer survival | N=3 |
| AGE | Spearman correlation test | N=0 | ||||
| GENDER | t test | N=54 | male | N=22 | female | N=32 |
| KARNOFSKY PERFORMANCE SCORE | Spearman correlation test | N=2 | higher score | N=1 | lower score | N=1 |
| HISTOLOGICAL TYPE | ANOVA test | N=16 | ||||
| PATHOLOGY T | Spearman correlation test | N=7 | higher pT | N=3 | lower pT | N=4 |
| PATHOLOGY N | Spearman correlation test | N=2 | higher pN | N=1 | lower pN | N=1 |
| PATHOLOGICSPREAD(M) | ANOVA test | N=25 | ||||
| TUMOR STAGE | Spearman correlation test | N=1 | higher stage | N=0 | lower stage | N=1 |
| RADIATIONS RADIATION REGIMENINDICATION | t test | N=1 | yes | N=0 | no | N=1 |
| NEOADJUVANT THERAPY | t test | N=0 | ||||
| NUMBERPACKYEARSSMOKED | Spearman correlation test | N=1 | higher numberpackyearssmoked | N=0 | lower numberpackyearssmoked | N=1 |
| STOPPEDSMOKINGYEAR | Spearman correlation test | N=1 | higher stoppedsmokingyear | N=1 | lower stoppedsmokingyear | N=0 |
| TOBACCOSMOKINGHISTORYINDICATOR | ANOVA test | N=3 | ||||
| YEAROFTOBACCOSMOKINGONSET | Spearman correlation test | N=0 |
