Testing the association between 17306 genes and 15 clinical features across 173 samples, statistically thresholded by Q value < 0.05, 9 clinical features related to at least one genes.
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8 genes correlated to 'Time to Death'.
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ANO9 , ATP6V0A1 , LOC100144604 , HCP5 , TM4SF19 , ...
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18 genes correlated to 'GENDER'.
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KIF4B , PPHLN1 , RNASEH2C , EIF4A1 , FAM35A , ...
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1 gene correlated to 'KARNOFSKY.PERFORMANCE.SCORE'.
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WDR4
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110 genes correlated to 'HISTOLOGICAL.TYPE'.
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GLTSCR2 , BCR , C8ORF42 , GAS2L3 , KRT39 , ...
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1 gene correlated to 'PATHOLOGY.T'.
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GAPDH
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19 genes correlated to 'PATHOLOGICSPREAD(M)'.
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C2ORF73 , C3ORF58 , YES1 , DENND2C , CYP2R1 , ...
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2 genes correlated to 'TUMOR.STAGE'.
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PCDHGC4 , PCDHGC5
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8 genes correlated to 'RADIATIONS.RADIATION.REGIMENINDICATION'.
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LYPLA2P1 , TRNP1 , GABARAPL3 , GPM6A , C3ORF47 , ...
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2 genes correlated to 'NEOADJUVANT.THERAPY'.
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FXYD5 , OSTALPHA
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No genes correlated to 'AGE', 'PATHOLOGY.N', 'NUMBERPACKYEARSSMOKED', 'STOPPEDSMOKINGYEAR', 'TOBACCOSMOKINGHISTORYINDICATOR', and 'YEAROFTOBACCOSMOKINGONSET'.
Complete statistical result table is provided in Supplement Table 1
Table 1. Get Full Table This table shows the clinical features, statistical methods used, and the number of genes that are significantly associated with each clinical feature at Q value < 0.05.
| Clinical feature | Statistical test | Significant genes | Associated with | Associated with | ||
|---|---|---|---|---|---|---|
| Time to Death | Cox regression test | N=8 | shorter survival | N=4 | longer survival | N=4 |
| AGE | Spearman correlation test | N=0 | ||||
| GENDER | t test | N=18 | male | N=6 | female | N=12 |
| KARNOFSKY PERFORMANCE SCORE | Spearman correlation test | N=1 | higher score | N=1 | lower score | N=0 |
| HISTOLOGICAL TYPE | ANOVA test | N=110 | ||||
| PATHOLOGY T | Spearman correlation test | N=1 | higher pT | N=0 | lower pT | N=1 |
| PATHOLOGY N | Spearman correlation test | N=0 | ||||
| PATHOLOGICSPREAD(M) | ANOVA test | N=19 | ||||
| TUMOR STAGE | Spearman correlation test | N=2 | higher stage | N=2 | lower stage | N=0 |
| RADIATIONS RADIATION REGIMENINDICATION | t test | N=8 | yes | N=3 | no | N=5 |
| NEOADJUVANT THERAPY | t test | N=2 | yes | N=1 | no | N=1 |
| NUMBERPACKYEARSSMOKED | Spearman correlation test | N=0 | ||||
| STOPPEDSMOKINGYEAR | Spearman correlation test | N=0 | ||||
| TOBACCOSMOKINGHISTORYINDICATOR | ANOVA test | N=0 | ||||
| YEAROFTOBACCOSMOKINGONSET | Spearman correlation test | N=0 |
