MutSigWithNozzleReport Execution Log 4:19 PM Thu Aug 16, '12

Running as user: cgaadm_deadline

MutSigPreprocess1 individual_set_id LUSC
MutSigPreprocess1 maf1 MutSigPreprocess1.maf1.input.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig1 MutSigPreprocess1.wig1.input.tsv
MutSigPreprocess1 build hg19
MutSigPreprocess1 context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
MutSigPreprocess1 build_dir /xchip/cga1/annotation/db/ucsc/hg19
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 individual_set_id LUSC
MutSigRun3 gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
MutSigRun3 build hg19
MutSigRun3 geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
MutSigRun3 build_dir /xchip/cga1/annotation/db/ucsc/hg19
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 jobcount 200
CoMut4 individualSetId LUSC
GDAC_MutSig_Report6 ind_set LUSC
Execution Times:
Submitted: 16:19:25 16-08-12
Completed:
Elapsed: 11 hrs 11 mins 24 secs

step 1. MutSigPreprocess [id: 146702] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:90
individual_set_id LUSC
maf1 MutSigPreprocess1.maf1.input.tsv
maf2
maf3
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1 MutSigPreprocess1.wig1.input.tsv
wig2
wig3
wig4
build hg19
context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
build_dir /xchip/cga1/annotation/db/ucsc/hg19
num_categories 4
target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
Output Files:
 LUSC.mutation_preprocessing_report.txt
 LUSC.patients.txt
 LUSC.coverage.prepare.txt
 LUSC.maf
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 16:19:25 16-08-12
Completed: 16:21:46 16-08-12
Elapsed: 00 hrs 02 mins 20 secs

step 2. ProcessCoverageForMutSig [id: 146703] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:77
coverage_prepare_file LUSC.coverage.prepare.txt
patient_list LUSC.patients.txt
mutation_list LUSC.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 LUSC.summed_coverage.fwi
 LUSC.summed_coverage.fwb
 LUSC.mutcateg_discovery.txt
 LUSC.mutcategs.txt
 LUSC.coverage.mat
 LUSC.covfiles
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 16:19:26 16-08-12
Completed: 17:12:10 16-08-12
Elapsed: 00 hrs 52 mins 44 secs

step 3. MutSigRun [id: 146704] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:160
individual_set_id LUSC
mutation_file LUSC.maf
coverage_file LUSC.coverage.mat
patient_file LUSC.patients.txt
category_file LUSC.mutcategs.txt
gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
build hg19
geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
build_dir /xchip/cga1/annotation/db/ucsc/hg19
param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
mutation_preprocessing_report_file LUSC.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 LUSC.MutSig_version.txt
 LUSC.mutation_filtering_report.txt
 LUSC.per_exon.coverage.txt
 LUSC.covplot.png
 LUSC.covplot_hires.png
 LUSC.patients.counts_and_rates.txt
 LUSC.bargraphs.png
 LUSC.bargraphs_hires.png
 LUSC.num_patients.txt
 LUSC.final_analysis_set.maf
 LUSC.mutcategs.txt
 LUSC.per_gene.coverage.txt
 LUSC.per_gene.mutation_counts.txt
 LUSC.mutation_breakdown.txt
 LUSC.mutsig2.images
 LUSC.mutation_rates.txt
 LUSC.sample_sig_gene_table.txt
 LUSC.sig_genes.txt
 LUSC.sig_genesets.txt
 LUSC.sig_genesets_2.txt
 LUSC.cosmic_sig_genes.txt
 LUSC.cosmic_sig_genes2.txt
 LUSC.cosmic_mutations.txt
 LUSC.cosmic_mutations.txt_verbose.txt
 LUSC.clustered_muts.txt
 LUSC.gene_gene_correlations.txt
 LUSC.power_per_gene.total_coverage.txt
 LUSC.power_per_gene.total_coverage_histogram
 LUSC.power_per_gene.power_stats.txt
 LUSC.power_per_gene.power_stats_full.txt
 LUSC.power_per_gene.power_summary.txt
 LUSC.gene_coverage_plots
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 16:19:26 16-08-12
Completed: 03:06:44 17-08-12
Elapsed: 10 hrs 47 mins 18 secs

step 4. CoMut [id: 146705]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00488:7
individualSetId LUSC
patientCRFile LUSC.patients.counts_and_rates.txt
mafFile LUSC.final_analysis_set.maf
mutcategsFile LUSC.mutcategs.txt
sigGenesFile LUSC.sig_genes.txt
Output Files:
 LUSC_coMut.png
 LUSC_coMut.pdf
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 16:19:26 16-08-12
Completed: 03:07:56 17-08-12
Elapsed: 10 hrs 48 mins 30 secs

step 5. GenerateStickFigures [id: 146706]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00497:4
maf LUSC.final_analysis_set.maf
sig_genes LUSC.sig_genes.txt
Output Files:
 TP53.stick_fig.txt
 TP53.stick_fig.png
 NFE2L2.stick_fig.txt
 NFE2L2.stick_fig.png
 PIK3CA.stick_fig.txt
 PIK3CA.stick_fig.png
 CDKN2A.stick_fig.txt
 CDKN2A.stick_fig.png
 TPTE.stick_fig.txt
 TPTE.stick_fig.png
 KEAP1.stick_fig.txt
 KEAP1.stick_fig.png
 PTEN.stick_fig.txt
 PTEN.stick_fig.png
 SI.stick_fig.txt
 TRIM58.stick_fig.txt
 SI.stick_fig.png
 ELTD1.stick_fig.txt
 TRIM58.stick_fig.png
 ELTD1.stick_fig.png
 FAM5C.stick_fig.txt
 OR5L2.stick_fig.txt
 FAM5C.stick_fig.png
 OR5L2.stick_fig.png
 REG1B.stick_fig.txt
 REG1B.stick_fig.png
 ZBBX.stick_fig.txt
 ZBBX.stick_fig.png
 LRRC4C.stick_fig.txt
 LRRC4C.stick_fig.png
 CYP11B1.stick_fig.txt
 CYP11B1.stick_fig.png
 OR4M2.stick_fig.txt
 OR4M2.stick_fig.png
 DPPA4.stick_fig.txt
 DPPA4.stick_fig.png
 OR2G6.stick_fig.txt
 OR2G6.stick_fig.png
 KRTAP5-5.stick_fig.txt
 CRB1.stick_fig.txt
 KRTAP5-5.stick_fig.png
 CRB1.stick_fig.png
 ASB5.stick_fig.txt
 ASB5.stick_fig.png
 PDYN.stick_fig.txt
 OR6F1.stick_fig.txt
 ESRRG.stick_fig.txt
 OR6F1.stick_fig.png
 ESRRG.stick_fig.png
 USP29.stick_fig.txt
 USP29.stick_fig.png
 CFHR4.stick_fig.txt
 C20orf26.stick_fig.txt
 CFHR4.stick_fig.png
 C20orf26.stick_fig.png
 SLC13A1.stick_fig.txt
 SLC13A1.stick_fig.png
 REG3G.stick_fig.txt
 REG3G.stick_fig.png
 CPS1.stick_fig.txt
 MAGEB2.stick_fig.txt
 CPS1.stick_fig.png
 OR51B2.stick_fig.txt
 MAGEB2.stick_fig.png
 OR51B2.stick_fig.png
 PNLIPRP3.stick_fig.txt
 PNLIPRP3.stick_fig.png
 SPANXN1.stick_fig.txt
 SPANXN1.stick_fig.png
 OR10G8.stick_fig.txt
 OR10G8.stick_fig.png
 RB1.stick_fig.txt
 MEF2D.stick_fig.txt
 RB1.stick_fig.png
 MEF2D.stick_fig.png
 OR2T33.stick_fig.txt
 OR2T33.stick_fig.png
 ASCL4.stick_fig.txt
 ASCL4.stick_fig.png
 ZEB2.stick_fig.txt
 ZEB2.stick_fig.png
 CBLN4.stick_fig.txt
 CBLN4.stick_fig.png
 OR2T8.stick_fig.txt
 PRIM2.stick_fig.txt
 OR2T8.stick_fig.png
 PRIM2.stick_fig.png
 PSG6.stick_fig.txt
 PSG6.stick_fig.png
 MTNR1B.stick_fig.txt
 MTNR1B.stick_fig.png
 CLSTN2.stick_fig.txt
 CLSTN2.stick_fig.png
 IFNA10.stick_fig.txt
 IFNA10.stick_fig.png
 RNF144A.stick_fig.txt
 OR2T2.stick_fig.txt
 RNF144A.stick_fig.png
 OR2T2.stick_fig.png
 MS4A14.stick_fig.txt
 MS4A14.stick_fig.png
 HIST2H2BE.stick_fig.txt
 HIST2H2BE.stick_fig.png
 TGIF2LX.stick_fig.txt
 REG3A.stick_fig.txt
 TGIF2LX.stick_fig.png
 TEX13A.stick_fig.txt
 REG3A.stick_fig.png
 TEX13A.stick_fig.png
 HS6ST1.stick_fig.txt
 HS6ST1.stick_fig.png
 SLC17A8.stick_fig.txt
 SLC17A8.stick_fig.png
 PARK2.stick_fig.txt
 SPHKAP.stick_fig.txt
 PARK2.stick_fig.png
 SPHKAP.stick_fig.png
 REG1A.stick_fig.txt
 REG1A.stick_fig.png
 OR5M9.stick_fig.txt
 OR5M9.stick_fig.png
 CLVS2.stick_fig.txt
 CLVS2.stick_fig.png
 NUCB2.stick_fig.txt
 NUCB2.stick_fig.png
 PSG2.stick_fig.txt
 PSG2.stick_fig.png
 PYHIN1.stick_fig.txt
 PYHIN1.stick_fig.png
 KCNJ3.stick_fig.txt
 HLA-A.stick_fig.txt
 KCNJ3.stick_fig.png
 HLA-A.stick_fig.png
 OR2A5.stick_fig.txt
 OR2A5.stick_fig.png
 KCND2.stick_fig.txt
 UXS1.stick_fig.txt
 KCND2.stick_fig.png
 UXS1.stick_fig.png
 OR8K5.stick_fig.txt
 OR8K5.stick_fig.png
 OR2AK2.stick_fig.txt
 TRAT1.stick_fig.txt
 OR2AK2.stick_fig.png
 TRAT1.stick_fig.png
 ZNF80.stick_fig.txt
 ZNF80.stick_fig.png
 FAM5B.stick_fig.txt
 FAM5B.stick_fig.png
 ZNF567.stick_fig.txt
 ZNF567.stick_fig.png
 TECRL.stick_fig.txt
 TECRL.stick_fig.png
 OR10A4.stick_fig.txt
 ZFP42.stick_fig.txt
 OR10A4.stick_fig.png
 ZFP42.stick_fig.png
 KIRREL2.stick_fig.txt
 KIRREL2.stick_fig.png
 GPC5.stick_fig.txt
 OR4M1.stick_fig.txt
 OR4M1.stick_fig.png
 POTEG.stick_fig.txt
 PRR23B.stick_fig.txt
 POTEG.stick_fig.png
 PRR23B.stick_fig.png
 OR5AC2.stick_fig.txt
 OR5AC2.stick_fig.png
 KRTAP10-7.stick_fig.txt
 KRTAP10-7.stick_fig.png
 GP2.stick_fig.txt
 GP2.stick_fig.png
 OR4C11.stick_fig.txt
 SPOPL.stick_fig.txt
 OR4C11.stick_fig.png
 SPOPL.stick_fig.png
 TRHDE.stick_fig.txt
 TRHDE.stick_fig.png
 LEPROT.stick_fig.txt
 APOBEC1.stick_fig.txt
 LEPROT.stick_fig.png
 LRRTM3.stick_fig.txt
 APOBEC1.stick_fig.png
 LRRTM3.stick_fig.png
 GABRA2.stick_fig.txt
 GABRA2.stick_fig.png
 SLC6A5.stick_fig.txt
 SLC6A5.stick_fig.png
 CALN1.stick_fig.txt
 CALN1.stick_fig.png
 OR6K3.stick_fig.txt
 CD5L.stick_fig.txt
 OR6K3.stick_fig.png
 CD5L.stick_fig.png
 LIN37.stick_fig.txt
 LIN37.stick_fig.png
 OR52J3.stick_fig.txt
 OR52J3.stick_fig.png
 OR8H2.stick_fig.txt
 OR8H2.stick_fig.png
 OR2T12.stick_fig.txt
 OR2T12.stick_fig.png
 OR8H1.stick_fig.txt
 GUCY1A2.stick_fig.txt
 OR8H1.stick_fig.png
 GUCY1A2.stick_fig.png
 DACH2.stick_fig.txt
 RTN1.stick_fig.txt
 DACH2.stick_fig.png
 RTN1.stick_fig.png
 HDAC9.stick_fig.txt
 HDAC9.stick_fig.png
 FRG2B.stick_fig.txt
 FRG2B.stick_fig.png
 SNAI1.stick_fig.txt
 SNAI1.stick_fig.png
 SCN7A.stick_fig.txt
 SCN7A.stick_fig.png
 C6orf97.stick_fig.txt
 C6orf97.stick_fig.png
 GBA3.stick_fig.txt
 GBA3.stick_fig.png
 RIMS2.stick_fig.txt
 RIMS2.stick_fig.png
 RPL10L.stick_fig.txt
 OR5AS1.stick_fig.txt
 RPL10L.stick_fig.png
 UGT3A2.stick_fig.txt
 OR5AS1.stick_fig.png
 UGT3A2.stick_fig.png
 CUL3.stick_fig.txt
 C8orf34.stick_fig.txt
 CUL3.stick_fig.png
 C8orf34.stick_fig.png
 OR8K3.stick_fig.txt
 OR8K3.stick_fig.png
 OR4N4.stick_fig.txt
 OR4N4.stick_fig.png
 SMPD4.stick_fig.txt
 SMPD4.stick_fig.png
 UBE2E2.stick_fig.txt
 UBE2E2.stick_fig.png
 PYGL.stick_fig.txt
 PYGL.stick_fig.png
 SLCO1B1.stick_fig.txt
 SLCO1B1.stick_fig.png
 ZIC1.stick_fig.txt
 ZIC1.stick_fig.png
 OR2M7.stick_fig.txt
 OR2M7.stick_fig.png
 COL6A6.stick_fig.txt
 COL6A6.stick_fig.png
 OR10Q1.stick_fig.txt
 OR10Q1.stick_fig.png
 KCNN2.stick_fig.txt
 ACSM2B.stick_fig.txt
 KCNN2.stick_fig.png
 ACSM2B.stick_fig.png
 EIF3E.stick_fig.txt
 EIF3E.stick_fig.png
 generatedStickFigurePaths.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 16:19:26 16-08-12
Completed: 03:30:01 17-08-12
Elapsed: 11 hrs 10 mins 35 secs

step 6. GDAC_MutSig_Report [id: 146707] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:16
bar_plot LUSC.bargraphs.png
breakdown_table LUSC.mutation_breakdown.txt
categories_table LUSC.mutation_rates.txt
coverage png LUSC.covplot.png
sig_table LUSC.sig_genes.txt
cosmic_table LUSC.cosmic_sig_genes.txt
cosmic_table2 LUSC.cosmic_sig_genes2.txt
cosmic_muts_table LUSC.cosmic_mutations.txt
cluster_table LUSC.clustered_muts.txt
geneset_table LUSC.sig_genesets.txt
genset_table2 LUSC.sig_genesets_2.txt
patients_c_and_r LUSC.patients.counts_and_rates.txt
ind_set LUSC
mutsig_version LUSC.MutSig_version.txt
coMut_plot_png LUSC_coMut.png
coMut_plot_pdf LUSC_coMut.pdf
stick_figures_path generatedStickFigurePaths.txt
maf_path LUSC.final_analysis_set.maf
mut_pre_rep_path LUSC.mutation_preprocessing_report.txt
mut_filt_rep_path LUSC.mutation_filtering_report.txt
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 16:19:26 16-08-12
Completed: 03:30:47 17-08-12
Elapsed: 11 hrs 11 mins 21 secs