Skin Cutaneous Melanoma: Clustering of RPPA data: consensus NMF
(Regional_LN cohort)
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
- Overview
+ Introduction
- Summary

The most robust consensus NMF clustering of 80 samples using the 175 most variable proteins was identified for k = 5 clusters. We computed the clustering for k = 2 to k = 8 and used the cophenetic correlation coefficient to determine the best solution.

- Results
+ Protein expression patterns of molecular subtypes
+ Consensus and correlation matrix
+ Silhouette widths
+ Samples assignment with silhouette width
+ Marker proteins of each subtype
+ Methods & Data