Thyroid Adenocarcinoma: Correlation between RPPA expression and clinical features
Maintained by Juok Cho (Broad Institute)
- Overview
+ Introduction
- Summary

Testing the association between 175 genes and 5 clinical features across 155 samples, statistically thresholded by Q value < 0.05, 4 clinical features related to at least one genes.

  • 18 genes correlated to 'AGE'.

    • SNAI2|SNAIL-M-C ,  AKT1 AKT2 AKT3|AKT_PS473-R-V ,  EEF2|EEF2-R-V ,  EGFR|EGFR_PY1068-R-V ,  PIK3R1|PI3K-P85-R-V ,  ...

  • 46 genes correlated to 'HISTOLOGICAL.TYPE'.

    • ANXA1|ANNEXIN_I-R-V ,  FN1|FIBRONECTIN-R-C ,  CHEK2|CHK2-M-C ,  IRS1|IRS1-R-V ,  C12ORF5|TIGAR-R-V ,  ...

  • 8 genes correlated to 'RADIATIONS.RADIATION.REGIMENINDICATION'.

    • ERBB2|HER2_PY1248-R-V ,  ARID1A|ARID1A-M-V ,  WWTR1|TAZ_PS89-R-C ,  CDKN1B|P27_PT157-R-C ,  MET|C-MET-M-C ,  ...

  • 2 genes correlated to 'NEOADJUVANT.THERAPY'.

    • NF2|NF2-R-C ,  EIF4E|EIF4E-R-V

  • No genes correlated to 'GENDER'

- Results
- Overview of the results

Complete statistical result table is provided in Supplement Table 1

Table 1.  Get Full Table This table shows the clinical features, statistical methods used, and the number of genes that are significantly associated with each clinical feature at Q value < 0.05.

Clinical feature Statistical test Significant genes Associated with                 Associated with
AGE Spearman correlation test N=18 older N=8 younger N=10
GENDER t test   N=0        
HISTOLOGICAL TYPE ANOVA test N=46        
RADIATIONS RADIATION REGIMENINDICATION t test N=8 yes N=6 no N=2
NEOADJUVANT THERAPY t test N=2 yes N=0 no N=2
+ Methods & Data