Thyroid Adenocarcinoma: Correlation between copy number variation genes and selected clinical features
Maintained by TCGA GDAC Team
(Broad Institute/Dana-Farber Cancer Institute/Harvard Medical School)
Overview
Introduction
Summary
Testing the association between copy number variation of 11 peak regions and 6 clinical features across 206 patients, one significant finding detected with Q value < 0.25.
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Del Peak 9(10q23.31) cnvs correlated to 'HISTOLOGICAL.TYPE'.
Results
Overview of the results
Table 1. Get Full Table Overview of the association between significant copy number variation of 11 regions and 6 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, one significant finding detected.
Clinical Features |
Time to Death |
AGE | GENDER |
HISTOLOGICAL TYPE |
RADIATIONS RADIATION REGIMENINDICATION |
NEOADJUVANT THERAPY |
||
nCNV (%) | nWild-Type | logrank test | t-test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
Del Peak 9(10q23 31) | 7 (3%) | 199 |
1 (1.00) |
0.0531 (1.00) |
0.377 (1.00) |
0.0021 (0.139) |
1 (1.00) |
1 (1.00) |
Del Peak 2(2p22 3) | 8 (4%) | 198 |
1 (1.00) |
0.154 (1.00) |
0.683 (1.00) |
0.217 (1.00) |
1 (1.00) |
1 (1.00) |
Del Peak 3(2q37 2) | 7 (3%) | 199 |
1 (1.00) |
0.00831 (0.532) |
0.68 (1.00) |
0.00693 (0.45) |
1 (1.00) |
1 (1.00) |
Del Peak 4(6q22 31) | 4 (2%) | 202 |
0.0143 (0.887) |
0.196 (1.00) |
1 (1.00) |
0.793 (1.00) |
0.247 (1.00) |
1 (1.00) |
Del Peak 6(8q24 22) | 4 (2%) | 202 |
1 (1.00) |
0.0353 (1.00) |
0.273 (1.00) |
0.147 (1.00) |
1 (1.00) |
1 (1.00) |
Del Peak 8(9q22 32) | 5 (2%) | 201 |
1 (1.00) |
0.0402 (1.00) |
1 (1.00) |
0.181 (1.00) |
0.299 (1.00) |
1 (1.00) |
Del Peak 10(13q21 1) | 10 (5%) | 196 |
0.0143 (0.887) |
0.407 (1.00) |
0.72 (1.00) |
0.0667 (1.00) |
0.141 (1.00) |
1 (1.00) |
Del Peak 14(17p13 1) | 3 (1%) | 203 |
1 (1.00) |
0.846 (1.00) |
0.571 (1.00) |
0.55 (1.00) |
0.0124 (0.783) |
1 (1.00) |
Del Peak 16(22q13 2) | 39 (19%) | 167 |
0.683 (1.00) |
0.954 (1.00) |
1 (1.00) |
0.444 (1.00) |
0.477 (1.00) |
1 (1.00) |
Del Peak 17(22q13 31) | 39 (19%) | 167 |
0.683 (1.00) |
0.954 (1.00) |
1 (1.00) |
0.444 (1.00) |
0.477 (1.00) |
1 (1.00) |
Del Peak 18(Xq22 3) | 3 (1%) | 203 |
1 (1.00) |
0.137 (1.00) |
0.163 (1.00) |
0.0914 (1.00) |
1 (1.00) |
1 (1.00) |
Methods & Data
Copyright © 2012
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.