Thyroid Adenocarcinoma: Correlations between copy number and mRNAseq expression
Maintained by TCGA GDAC Team (Broad Institute/Dana-Farber Cancer Institute/Harvard Medical School)
- Overview
+ Introduction
- Summary

The correlation coefficients in 10, 20, 30, 40, 50, 60, 70, 80, 90 percentiles are 513, 1339.8, 2009, 2376, 2753, 3135, 3592, 4129, 4816.6, respectively.

- Results
- Correlation results

Number of genes and samples used for the calculation are shown in Table 1. Figure 1 shows the distribution of calculated correlation coefficients and quantile-quantile plot of the calculated correlation coefficients against a normal distribution. Table 2 shows the top 20 features ordered by the value of correlation coefficients.

Table 1.  Counts of mRNAseq and number of samples in copy number and expression data sets and common to both

Category Copy number Expression Common
Sample 330 254 252
Genes 23778 17972 17885

Figure 1.  Summary figures. Left: histogram showing the distribution of the calculated correlations across samples for all Genes. Right: QQ plot of the calculated correlations across samples. The QQ plot is used to plot the quantiles of the calculated correlation coefficients against that derived from a normal distribution. Points deviating from the blue line indicate deviation from normality.

Table 2.  Get Full Table Top 20 features (defined by the feature column) ranked by correlation coefficients

Locus ID Gene Symbol Cytoband cor p-value q-value
2547 XRCC6 22q13.2 0.7924 0 0
24144 TFIP11 22q12.1 0.7792 0 0
51493 C22orf28 22q12.3 0.7683 0 0
10454 TAB1 22q13.1 0.7677 0 0
158 ADSL 22q13.1 0.7536 0 0
6767 ST13 22q13.2 0.7515 0 0
51386 EIF3L 22q13.1 0.7442 0 0
23760 PITPNB 22q12.1 0.7355 0 0
83606 C22orf13 22q11.23 0.7245 0 0
54471 SMCR7L 22q13.1 0.7213 0 0
51557 LGSN 6q12 0.7201 4.44089209850063e-16 1.19427230696828e-14
83746 L3MBTL2 22q13.2 0.7195 0 0
56478 EIF4ENIF1 22q12.2 0.7191 0 0
6598 SMARCB1 22q11.23 0.7122 0 0
4733 DRG1 22q12.2 0.712 0 0
9701 PPP6R2 22q13.33 0.7119 0 0
25771 TBC1D22A 22q13.31 0.709 0 0
23786 BCL2L13 22q11.21 0.7051 0 0
23481 PES1 22q12.2 0.7018 0 0
9512 PMPCB 7q22.1 0.6989 0 0
+ Methods & Data