Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Genome_Change	Annotation_Transcript	Transcript_Strand	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	i_TCGAscape_Amplification_Peaks	i_TCGAscape_Deletion_Peaks	DrugBank	i_ACHILLES_Top_Genes	i_CCLE_ONCOMAP_overlapping_mutations	i_CCLE_ONCOMAP_total_mutations_in_gene	i_CCLE_SEQ_overlapping_mutations	i_CCLE_SEQ_total_mutations_in_gene	MUTSIG_Significant_Genes	OREGANNO_ID	OREGANNO_Values	i_tumor_f	i_init_t_lod	i_t_lod_fstar	i_t_alt_count	i_t_ref_count	i_normal_best_gt	i_failure_reasons	i_judgement	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	dataset	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	type	classification	start	end	gene	chr	ref_allele	tum_allele1	tum_allele2	context_orig	context65	gene_name	newbase	categ	categ_ignoring_null_categ
ABCG4	64137	broad.mit.edu	36	11	118536878	118536878	+	Missense_Mutation	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr11:118536878C>T	uc001pvs.1	+	c.1793C>T	c.(1792-1794)CCG>CTG	p.P598L	ABCG4_uc009zar.1_Missense_Mutation_p.P598L	NM_022169	NP_071452	Q9H172	ABCG4_HUMAN	ATP-binding cassette, subfamily G, member 4	598	Extracellular (Potential).|ABC transmembrane type-2.				cholesterol efflux	integral to membrane	ATP binding|ATPase activity|protein heterodimerization activity|protein homodimerization activity			ovary(2)	2	all_hematologic(175;0.0977)	Medulloblastoma(222;0.0425)|Breast(348;0.052)|all_neural(223;0.112)												0.142857	13.266521	20.14625	8	48	CC		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(274;7.7e-05)	Missense_Mutation	SNP	118536878	118536878	71	11	C	T	T	23	23	ABCG4	T	1	1
FOXN4	121643	broad.mit.edu	36	12	108203621	108203621	+	Missense_Mutation	SNP	G	A	A			TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:108203621G>A	uc001toe.2	-	c.1268C>T	c.(1267-1269)CCG>CTG	p.P423L	FOXN4_uc009zvf.1_Missense_Mutation_p.P243L|FOXN4_uc009zvg.1_Missense_Mutation_p.P220L|FOXN4_uc001tof.2_Missense_Mutation_p.P243L	NM_213596	NP_998761	Q96NZ1	FOXN4_HUMAN	forkhead box N4	423					axon extension|embryo development|negative regulation of gene-specific transcription from RNA polymerase II promoter|organ development|pattern specification process|positive regulation of gene-specific transcription|regulation of heart contraction|regulation of sequence-specific DNA binding transcription factor activity|tissue development	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding			ovary(1)|lung(1)	2														0.122137	17.50581	35.830138	16	115	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	108203621	108203621	6268	12	G	A	A	39	39	FOXN4	A	1	1
OR9K2	441639	broad.mit.edu	36	12	53810652	53810652	+	Missense_Mutation	SNP	G	A	A			TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:53810652G>A	uc001sgq.1	+	c.833G>A	c.(832-834)GGT>GAT	p.G278D		NM_001005243	NP_001005243	Q8NGE7	OR9K2_HUMAN	olfactory receptor, family 9, subfamily K,	278	Helical; Name=6; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			central_nervous_system(1)|pancreas(1)	2														0.123839	47.048932	91.806276	40	283	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	53810652	53810652	11665	12	G	A	A	44	44	OR9K2	A	2	2
SERPINA12	145264	broad.mit.edu	36	14	94023572	94023572	+	Missense_Mutation	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr14:94023572C>T	uc001ydj.1	-	c.1066G>A	c.(1066-1068)GCT>ACT	p.A356T		NM_173850	NP_776249	Q8IW75	SPA12_HUMAN	serine (or cysteine) proteinase inhibitor, clade	356					regulation of proteolysis	extracellular region	serine-type endopeptidase inhibitor activity			central_nervous_system(2)|ovary(1)|lung(1)	4										148				0.175926	35.760146	46.455615	19	89	CC		KEEP	---	---	---	---	capture		COAD - Colon adenocarcinoma(157;0.235)	Missense_Mutation	SNP	94023572	94023572	14577	14	C	T	T	26	26	SERPINA12	T	2	2
NLRP12	91662	broad.mit.edu	36	19	59005554	59005554	+	Missense_Mutation	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr19:59005554C>T	uc002qcj.2	-	c.1171G>A	c.(1171-1173)GTG>ATG	p.V391M	NLRP12_uc010eqw.1_5'Flank|NLRP12_uc002qch.2_Missense_Mutation_p.V391M|NLRP12_uc002qci.2_Missense_Mutation_p.V391M|NLRP12_uc002qck.2_Non-coding_Transcript|NLRP12_uc010eqx.1_Missense_Mutation_p.V391M	NM_144687	NP_653288	P59046	NAL12_HUMAN	NLR family, pyrin domain containing 12 isoform	391	NACHT.				activation of caspase activity|negative regulation of I-kappaB kinase/NF-kappaB cascade|negative regulation of interleukin-1 secretion|negative regulation of interleukin-6 biosynthetic process|negative regulation of protein autophosphorylation|negative regulation of Toll signaling pathway|positive regulation of inflammatory response|positive regulation of interleukin-1 beta secretion|regulation of interleukin-18 biosynthetic process|release of cytoplasmic sequestered NF-kappaB	cytoplasm	ATP binding|caspase activator activity|protein binding			ovary(4)|lung(1)	5	Ovarian(34;0.19)													0.113314	33.300945	85.354723	40	313	CC		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(134;0.026)	Missense_Mutation	SNP	59005554	59005554	10877	19	C	T	T	19	19	NLRP12	T	1	1
PSMA5	5686	broad.mit.edu	36	1	109766046	109766046	+	Missense_Mutation	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:109766046C>T	uc001dxn.1	-	c.55G>A	c.(55-57)GGA>AGA	p.G19R		NM_002790	NP_002781	P28066	PSA5_HUMAN	proteasome alpha 5 subunit	19					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle|mRNA metabolic process|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|regulation of apoptosis|regulation of cellular amino acid metabolic process|S phase of mitotic cell cycle|viral reproduction	cytoplasm|nucleus|proteasome core complex, alpha-subunit complex	protein binding|threonine-type endopeptidase activity				0		all_epithelial(167;2.83e-05)|all_lung(203;0.00016)|Lung NSC(277;0.000318)|Breast(1374;0.244)												0.152174	27.485394	38.142775	14	78	CC		KEEP	---	---	---	---	capture		Lung(183;0.045)|Colorectal(144;0.116)|Epithelial(280;0.187)|all cancers(265;0.196)|LUSC - Lung squamous cell carcinoma(189;0.235)	Missense_Mutation	SNP	109766046	109766046	13123	1	C	T	T	24	24	PSMA5	T	2	2
SPAG17	200162	broad.mit.edu	36	1	118441960	118441960	+	Missense_Mutation	SNP	T	C	C			TCGA-06-0132-01	TCGA-06-0132-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr1:118441960T>C	uc001ehk.1	-	c.867A>G	c.(865-867)ATA>ATG	p.I289M		NM_206996	NP_996879	Q6Q759	SPG17_HUMAN	sperm associated antigen 17	289	Potential.					cilium|flagellar axoneme|microtubule				ovary(2)|large_intestine(1)	3	Esophageal squamous(2;0.0106)	all_cancers(81;0.0204)|all_lung(203;9.46e-05)|Lung NSC(69;0.000675)|all_epithelial(167;0.01)												0.121212	22.234296	36.148703	12	87	TT		KEEP	---	---	---	---	capture		Lung(183;0.0858)	Missense_Mutation	SNP	118441960	118441960	15482	1	T	C	C	61	61	SPAG17	C	4	4
FCRLA	84824	broad.mit.edu	36	1	159949535	159949535	+	Missense_Mutation	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:159949535C>T	uc001gbe.1	+	c.890C>T	c.(889-891)CCA>CTA	p.P297L	FCRLA_uc001gbd.1_Missense_Mutation_p.P291L|FCRLA_uc001gbf.1_Missense_Mutation_p.P202L|FCRLA_uc001gbg.1_Missense_Mutation_p.P151L|FCRLA_uc009wuo.1_Missense_Mutation_p.P157L|FCRLA_uc009wup.1_Missense_Mutation_p.P107L|FCRLA_uc009wuq.1_Missense_Mutation_p.P56L|FCRLA_uc009wur.1_Missense_Mutation_p.P152L	NM_032738	NP_116127	Q7L513	FCRLA_HUMAN	Fc receptor-like and mucin-like 1	274	Pro-rich.				cell differentiation	cytoplasm|extracellular region					0	all_cancers(52;2.55e-15)|all_hematologic(112;0.0359)													0.094421	12.278876	50.776132	22	211	CC		KEEP	---	---	---	---	capture	BRCA - Breast invasive adenocarcinoma(70;0.00301)		Missense_Mutation	SNP	159949535	159949535	6037	1	C	T	T	21	21	FCRLA	T	2	2
CACNA1S	779	broad.mit.edu	36	1	199279219	199279219	+	Missense_Mutation	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:199279219C>T	uc001gvv.1	-	c.4861G>A	c.(4861-4863)GTC>ATC	p.V1621I		NM_000069	NP_000060	Q13698	CAC1S_HUMAN	calcium channel, voltage-dependent, L type,	1621	Cytoplasmic (Potential).				axon guidance	I band|T-tubule|voltage-gated calcium channel complex	high voltage-gated calcium channel activity			ovary(3)|central_nervous_system(1)	4					Magnesium Sulfate(DB00653)|Verapamil(DB00661)							OREG0014067	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.139535	24.28731	40.463421	18	111	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	199279219	199279219	2663	1	C	T	T	19	19	CACNA1S	T	1	1
CAMTA1	23261	broad.mit.edu	36	1	7646584	7646584	+	Silent	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:7646584C>T	uc001aoi.1	+	c.1390C>T	c.(1390-1392)CTG>TTG	p.L464L		NM_015215	NP_056030	Q9Y6Y1	CMTA1_HUMAN	calmodulin-binding transcription activator 1	464					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	calmodulin binding|transcription regulator activity			ovary(5)|central_nervous_system(2)|breast(1)|pancreas(1)	9	Ovarian(185;0.0634)	all_epithelial(116;8.38e-23)|all_lung(118;5.87e-07)|Lung NSC(185;3.43e-06)|Renal(390;0.000219)|Breast(487;0.000307)|Colorectal(325;0.000615)|Hepatocellular(190;0.0088)|Myeloproliferative disorder(586;0.0303)|Ovarian(437;0.0388)												0.150327	33.330007	51.266707	23	130	CC		KEEP	---	---	---	---	capture		UCEC - Uterine corpus endometrioid carcinoma (279;0.101)|Colorectal(212;1.33e-05)|COAD - Colon adenocarcinoma(227;0.000235)|BRCA - Breast invasive adenocarcinoma(304;0.000864)|Kidney(185;0.00244)|STAD - Stomach adenocarcinoma(132;0.00644)|KIRC - Kidney renal clear cell carcinoma(229;0.0179)|READ - Rectum adenocarcinoma(331;0.133)	Silent	SNP	7646584	7646584	2730	1	C	T	T	28	28	CAMTA1	T	2	2
PLXNB2	23654	broad.mit.edu	36	22	49063290	49063290	+	Missense_Mutation	SNP	G	C	C			TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr22:49063290G>C	uc003bkv.2	-	c.2964C>G	c.(2962-2964)TTC>TTG	p.F988L	PLXNB2_uc003bkt.1_5'Flank|PLXNB2_uc003bku.1_5'Flank	NM_012401	NP_036533	O15031	PLXB2_HUMAN	plexin B2	988	IPT/TIG 3.|Extracellular (Potential).				regulation of small GTPase mediated signal transduction	integral to membrane|intracellular	GTPase activator activity|protein binding|receptor activity			ovary(4)|central_nervous_system(1)	5		all_cancers(38;5.78e-13)|all_epithelial(38;1.71e-11)|all_lung(38;3.89e-05)|Breast(42;0.000523)|Lung NSC(38;0.000992)|Ovarian(80;0.0221)|Hepatocellular(38;0.0691)|Lung SC(80;0.113)												0.333333	9.995218	10.290817	4	8	GG		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(115;0.205)|LUAD - Lung adenocarcinoma(64;0.247)	Missense_Mutation	SNP	49063290	49063290	12550	22	G	C	C	37	37	PLXNB2	C	3	3
MBD5	55777	broad.mit.edu	36	2	148964528	148964528	+	Silent	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:148964528C>T	uc002twm.2	+	c.4158C>T	c.(4156-4158)GGC>GGT	p.G1386G	MBD5_uc010fns.1_Silent_p.G1386G|MBD5_uc002two.1_Silent_p.G644G|MBD5_uc002twp.1_Silent_p.G436G	NM_018328	NP_060798	Q9P267	MBD5_HUMAN	methyl-CpG binding domain protein 5	1386	PWWP.					chromosome|nucleus	chromatin binding|DNA binding			ovary(2)	2														0.150442	27.309716	40.537425	17	96	CC		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(221;0.0569)	Silent	SNP	148964528	148964528	9735	2	C	T	T	27	27	MBD5	T	1	1
SCN9A	6335	broad.mit.edu	36	2	166763916	166763916	+	Missense_Mutation	SNP	C	A	A			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:166763916C>A	uc002udq.2	-	c.5446G>T	c.(5446-5448)GAT>TAT	p.D1816Y		NM_002977	NP_002968	Q15858	SCN9A_HUMAN	sodium channel, voltage-gated, type IX, alpha	1827						voltage-gated sodium channel complex	voltage-gated sodium channel activity			ovary(6)|central_nervous_system(5)	11					Lamotrigine(DB00555)|Lidocaine(DB00281)									0.121495	27.286685	57.344322	26	188	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	166763916	166763916	14407	2	C	A	A	30	30	SCN9A	A	3	3
YIPF4	84272	broad.mit.edu	36	2	32384090	32384090	+	Missense_Mutation	SNP	G	A	A			TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr2:32384090G>A	uc002rok.1	+	c.626G>A	c.(625-627)AGT>AAT	p.S209N		NM_032312	NP_115688	Q9BSR8	YIPF4_HUMAN	Yip1 domain family, member 4	209	Helical; (Potential).					endoplasmic reticulum|integral to membrane	protein binding				0	Acute lymphoblastic leukemia(172;0.155)													0.100671	12.305861	36.033409	15	134	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	32384090	32384090	18063	2	G	A	A	36	36	YIPF4	A	2	2
SMYD1	150572	broad.mit.edu	36	2	88168501	88168501	+	Missense_Mutation	SNP	C	G	G			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:88168501C>G	uc002ssr.1	+	c.320C>G	c.(319-321)GCG>GGG	p.A107G	SMYD1_uc002ssq.1_Intron	NM_198274	NP_938015	Q8NB12	SMYD1_HUMAN	SET and MYND domain containing 1	107					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|zinc ion binding	p.A107V(1)		ovary(2)|lung(1)	3														0.5	7.053234	7.053234	6	6	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	88168501	88168501	15321	2	C	G	G	27	27	SMYD1	G	3	3
CHL1	10752	broad.mit.edu	36	3	358663	358663	+	Missense_Mutation	SNP	G	A	A			TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr3:358663G>A	uc003bot.1	+	c.577G>A	c.(577-579)GTG>ATG	p.V193M	CHL1_uc003bou.1_Missense_Mutation_p.V193M|CHL1_uc003bow.1_Missense_Mutation_p.V193M	NM_006614	NP_006605	O00533	CHL1_HUMAN	cell adhesion molecule with homology to L1CAM	193	Ig-like C2-type 2.|Extracellular (Potential).				axon guidance|cell adhesion|signal transduction	integral to membrane|plasma membrane|proteinaceous extracellular matrix				central_nervous_system(4)|large_intestine(2)|ovary(1)	7		all_cancers(2;1.14e-06)|all_epithelial(2;0.00367)|all_lung(1;0.061)|Lung NSC(2;0.201)								659				0.150685	18.475995	27.012986	11	62	GG		KEEP	---	---	---	---	capture		Epithelial(13;5.36e-06)|all cancers(10;1.4e-05)|OV - Ovarian serous cystadenocarcinoma(96;0.00323)|COAD - Colon adenocarcinoma(1;0.00925)|Colorectal(20;0.0198)	Missense_Mutation	SNP	358663	358663	3483	3	G	A	A	40	40	CHL1	A	1	1
VPRBP	9730	broad.mit.edu	36	3	51431319	51431319	+	Silent	SNP	G	A	A			TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr3:51431319G>A	uc003dbe.1	-	c.3288C>T	c.(3286-3288)TTC>TTT	p.F1096F	VPRBP_uc003dbf.1_Silent_p.F372F	NM_014703	NP_055518	Q9Y4B6	VPRBP_HUMAN	HIV-1 Vpr binding protein	1096	WD 1.|WD repeat-like region.				interspecies interaction between organisms	cytoplasm|nucleus	protein binding			ovary(1)|skin(1)	2														0.269231	6.469667	7.853139	7	19	GG		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(193;0.000272)|Kidney(197;0.000729)|KIRC - Kidney renal clear cell carcinoma(197;0.000875)	Silent	SNP	51431319	51431319	17752	3	G	A	A	45	45	VPRBP	A	2	2
SPOCK3	50859	broad.mit.edu	36	4	167892734	167892734	+	Silent	SNP	A	G	G			TCGA-06-0132-01	TCGA-06-0132-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr4:167892734A>G	uc003iri.1	-	c.1224T>C	c.(1222-1224)ATT>ATC	p.I408I	SPOCK3_uc003irj.1_Silent_p.I405I	NM_016950	NP_058646	Q9BQ16	TICN3_HUMAN	testican 3 isoform 2	408	Asp-rich.				signal transduction	proteinaceous extracellular matrix	calcium ion binding|metalloendopeptidase inhibitor activity			large_intestine(1)|ovary(1)|central_nervous_system(1)	3	all_hematologic(180;0.221)	Prostate(90;0.0181)|Renal(120;0.0184)|Melanoma(52;0.0198)												0.1625	31.629638	40.286311	13	67	AA		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(119;0.02)	Silent	SNP	167892734	167892734	15594	4	A	G	G	13	13	SPOCK3	G	4	4
HMP19	51617	broad.mit.edu	36	5	173467064	173467064	+	Missense_Mutation	SNP	G	C	C			TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr5:173467064G>C	uc003mcx.1	+	c.466G>C	c.(466-468)GCA>CCA	p.A156P		NM_015980	NP_057064	Q9Y328	NSG2_HUMAN	HMP19 protein	156	Lumenal (Potential).				dopamine receptor signaling pathway	cytoplasmic vesicle membrane|Golgi cisterna membrane|integral to membrane|multivesicular body membrane	dopamine receptor binding			central_nervous_system(1)	1	Renal(175;0.000159)|Lung NSC(126;0.00925)|all_lung(126;0.0148)	Medulloblastoma(196;0.0399)|all_neural(177;0.0966)												0.222222	6.401596	7.67373	4	14	GG		KEEP	---	---	---	---	capture	Kidney(164;3.85e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000183)		Missense_Mutation	SNP	173467064	173467064	7537	5	G	C	C	34	34	HMP19	C	3	3
PDE1C	5137	broad.mit.edu	36	7	31871135	31871135	+	Silent	SNP	G	A	A	rs61734907	unknown	TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr7:31871135G>A	uc003tco.1	-	c.876C>T	c.(874-876)CAC>CAT	p.H292H	PDE1C_uc003tcm.1_Silent_p.H232H|PDE1C_uc003tcn.1_Silent_p.H232H|PDE1C_uc003tcr.1_Silent_p.H232H|PDE1C_uc003tcs.1_Silent_p.H232H	NM_005020	NP_005011	Q14123	PDE1C_HUMAN	phosphodiesterase 1C, calmodulin-dependent	232	Catalytic (By similarity).	Divalent metal cation 1 (By similarity).			activation of phospholipase C activity|nerve growth factor receptor signaling pathway	cytosol	calmodulin binding|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|metal ion binding			central_nervous_system(1)	1														0.103261	10.37695	39.260267	19	165	GG		KEEP	---	---	---	---	capture	GBM - Glioblastoma multiforme(11;0.216)		Silent	SNP	31871135	31871135	12056	7	G	A	A	40	40	PDE1C	A	1	1
SUSD1	64420	broad.mit.edu	36	9	113880768	113880768	+	Missense_Mutation	SNP	T	C	C			TCGA-06-0132-01	TCGA-06-0132-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr9:113880768T>C	uc004bfu.1	-	c.1624A>G	c.(1624-1626)AAT>GAT	p.N542D	SUSD1_uc010mui.1_Missense_Mutation_p.N542D|SUSD1_uc010muj.1_Missense_Mutation_p.N542D	NM_022486	NP_071931	Q6UWL2	SUSD1_HUMAN	sushi domain containing 1	542	Extracellular (Potential).					integral to membrane	calcium ion binding				0														0.167665	65.404692	82.873017	28	139	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	113880768	113880768	15927	9	T	C	C	61	61	SUSD1	C	4	4
PIP5K1B	8395	broad.mit.edu	36	9	70745517	70745517	+	Missense_Mutation	SNP	A	C	C			TCGA-06-0132-01	TCGA-06-0132-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr9:70745517A>C	uc004agu.1	+	c.1493A>C	c.(1492-1494)TAT>TCT	p.Y498S	PIP5K1B_uc004agv.1_Non-coding_Transcript|PIP5K1B_uc010mok.1_Missense_Mutation_p.Y342S	NM_003558	NP_003549	O14986	PI51B_HUMAN	phosphatidylinositol-4-phosphate 5-kinase, type	498						endomembrane system|membrane|uropod	1-phosphatidylinositol-4-phosphate 5-kinase activity|ATP binding|protein binding				0										223				0.147465	68.471729	94.356146	32	185	AA		KEEP	---	---	---	---	capture		Lung(182;0.133)	Missense_Mutation	SNP	70745517	70745517	12364	9	A	C	C	16	16	PIP5K1B	C	4	4
OR13H1	347468	broad.mit.edu	36	X	130506030	130506030	+	Missense_Mutation	SNP	C	T	T			TCGA-06-0132-01	TCGA-06-0132-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chrX:130506030C>T	uc004ewh.1	+	c.302C>T	c.(301-303)ACG>ATG	p.T101M	IGSF1_uc004ewf.1_Intron	NM_001004486	NP_001004486	Q8NG92	O13H1_HUMAN	olfactory receptor, family 13, subfamily H,	101	Helical; Name=3; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity				0	Acute lymphoblastic leukemia(192;0.000636)													0.270833	62.534698	67.065681	26	70	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	130506030	130506030	11349	23	C	T	T	19	19	OR13H1	T	1	1
CXorf59	286464	broad.mit.edu	36	X	36013388	36013388	+	Silent	SNP	G	A	A			TCGA-06-0132-01	TCGA-06-0132-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chrX:36013388G>A	uc004ddk.1	+	c.453G>A	c.(451-453)TCG>TCA	p.S151S		NM_173695	NP_775966	Q8N9S7	CX059_HUMAN	hypothetical protein LOC286464	151						integral to membrane				central_nervous_system(1)	1														0.171429	31.984092	42.703082	18	87	GG		KEEP	---	---	---	---	capture			Silent	SNP	36013388	36013388	4279	23	G	A	A	38	38	CXorf59	A	1	1
NCOR2	9612	broad.mit.edu	36	12	123376022	123376023	+	Frame_Shift_Ins	INS	-	A	A			TCGA-06-0132-01	TCGA-06-0132-01										Phase_I	Unspecified				Illumina GAIIx	g.chr12:123376022_123376023insA	uc009zyd.1	-	c.7453_7454insT	c.(7453-7455)TCCfs	p.S2485fs	NCOR2_uc009zye.1_Frame_Shift_Ins_p.S2423fs	NM_006312	NP_006303	Q9Y618	NCOR2_HUMAN	nuclear receptor co-repressor 2 isoform 1	2486					cellular lipid metabolic process|negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|regulation of cellular ketone metabolic process by negative regulation of transcription from an RNA polymerase II promoter|transcription, DNA-dependent	nuclear body|nucleus|transcriptional repressor complex	DNA binding|histone deacetylase binding|Notch binding|protein N-terminus binding|transcription corepressor activity|transcription repressor activity			ovary(1)|skin(1)	2	all_neural(191;0.0804)|Medulloblastoma(191;0.163)			Epithelial(86;3.99e-05)|OV - Ovarian serous cystadenocarcinoma(86;9.14e-05)|all cancers(50;0.000402)|BRCA - Breast invasive adenocarcinoma(302;0.0764)										0.33			2	4				---	---	---	---	capture_indel			Frame_Shift_Ins	INS	123376022	123376023	10635	12	-	A	A	41	41	NCOR2	A	5	5
C9orf150	286343	broad.mit.edu	36	9	12765861	12765862	+	In_Frame_Ins	INS	-	GGCGGCGGC	GGCGGCGGC			TCGA-06-0132-01	TCGA-06-0132-01										Phase_I	Unspecified				Illumina GAIIx	g.chr9:12765861_12765862insGGCGGCGGC	uc003zkw.1	+	c.147_148insGGCGGCGGC	c.(145-150)insGGCGGCGGC	p.55_56insGGG		NM_203403	NP_981948	Q8IV03	CI150_HUMAN	hypothetical protein LOC286343	58_59	Gly-rich.										0				GBM - Glioblastoma multiforme(1;1.64e-13)										0.40			4	6				---	---	---	---	capture_indel			In_Frame_Ins	INS	12765861	12765862	2576	9	-	GGCGGCGGC	GGCGGCGGC	59	59	C9orf150	GGCGGCGGC	5	5
