Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Genome_Change	Annotation_Transcript	Transcript_Strand	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	i_TCGAscape_Amplification_Peaks	i_TCGAscape_Deletion_Peaks	DrugBank	i_ACHILLES_Top_Genes	i_CCLE_ONCOMAP_overlapping_mutations	i_CCLE_ONCOMAP_total_mutations_in_gene	i_CCLE_SEQ_overlapping_mutations	i_CCLE_SEQ_total_mutations_in_gene	MUTSIG_Significant_Genes	OREGANNO_ID	OREGANNO_Values	i_tumor_f	i_init_t_lod	i_t_lod_fstar	i_t_alt_count	i_t_ref_count	i_normal_best_gt	i_failure_reasons	i_judgement	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	dataset	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	type	classification	start	end	gene	chr	ref_allele	tum_allele1	tum_allele2	context_orig	context65	gene_name	newbase	categ	categ_ignoring_null_categ
DLG5	9231	broad.mit.edu	36	10	79251228	79251228	+	Missense_Mutation	SNP	G	A	A			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr10:79251228G>A	uc001jzk.1	-	c.3020C>T	c.(3019-3021)GCG>GTG	p.A1007V	DLG5_uc009xru.1_Non-coding_Transcript|DLG5_uc001jzi.1_5'Flank|DLG5_uc001jzj.1_Intron|DLG5_uc001jzl.2_Missense_Mutation_p.A611V	NM_004747	NP_004738	Q8TDM6	DLG5_HUMAN	discs large homolog 5	1007	Pro-rich.				cell-cell adhesion|intracellular signal transduction|negative regulation of cell proliferation|regulation of apoptosis	cell junction|cytoplasm	beta-catenin binding|cytoskeletal protein binding|receptor signaling complex scaffold activity			ovary(5)|breast(3)	8	all_cancers(46;0.0316)|all_epithelial(25;0.00147)|Breast(12;0.0015)|Prostate(51;0.0146)													0.242105	49.418527	55.157995	23	72	GG		KEEP	---	---	---	---	capture	Epithelial(14;0.00105)|OV - Ovarian serous cystadenocarcinoma(4;0.00151)|all cancers(16;0.00446)		Missense_Mutation	SNP	79251228	79251228	4738	10	G	A	A	38	38	DLG5	A	1	1
CDHR1	92211	broad.mit.edu	36	10	85962070	85962070	+	Missense_Mutation	SNP	A	G	G			TCGA-26-1442-01	TCGA-26-1442-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr10:85962070A>G	uc001kcv.1	+	c.1709A>G	c.(1708-1710)AAT>AGT	p.N570S	CDHR1_uc001kcw.2_Missense_Mutation_p.N570S|CDHR1_uc009xst.1_Missense_Mutation_p.N274S|CDHR1_uc001kcx.1_5'Flank	NM_033100	NP_149091	Q96JP9	CDHR1_HUMAN	protocadherin 21 precursor	570	Cadherin 5.|Extracellular (Potential).				homophilic cell adhesion		calcium ion binding|receptor activity			ovary(1)	1														0.142857	23.892345	35.930942	14	84	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	85962070	85962070	3247	10	A	G	G	4	4	CDHR1	G	4	4
MRVI1	10335	broad.mit.edu	36	11	10630260	10630260	+	Missense_Mutation	SNP	G	A	A			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr11:10630260G>A	uc001miw.2	-	c.86C>T	c.(85-87)GCG>GTG	p.A29V	MRVI1_uc009ygb.1_5'UTR|MRVI1_uc001mix.2_5'UTR|MRVI1_uc001miz.2_Intron|MRVI1_uc009ygc.1_Intron|MRVI1_uc009ygd.1_Intron	NM_001098579	NP_001092049	Q9Y6F6	MRVI1_HUMAN	JAW1-related protein isoform a	29					platelet activation	endoplasmic reticulum membrane|integral to membrane|perinuclear region of cytoplasm|platelet dense tubular network membrane|sarcoplasmic reticulum				ovary(2)|central_nervous_system(1)	3														0.4375	19.923519	19.977767	7	9	GG		KEEP	---	---	---	---	capture		all cancers(16;2.68e-07)|Epithelial(150;3.04e-07)|BRCA - Breast invasive adenocarcinoma(625;0.0723)	Missense_Mutation	SNP	10630260	10630260	10246	11	G	A	A	38	38	MRVI1	A	1	1
TRPM5	29850	broad.mit.edu	36	11	2391307	2391307	+	Missense_Mutation	SNP	C	T	T			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr11:2391307C>T	uc009ydn.1	-	c.1984G>A	c.(1984-1986)GTC>ATC	p.V662I	TRPM5_uc001lwm.2_Missense_Mutation_p.V660I	NM_014555	NP_055370	Q9NZQ8	TRPM5_HUMAN	transient receptor potential cation channel,	660	Helical; (Potential).					integral to membrane|plasma membrane	receptor activity|voltage-gated ion channel activity			ovary(1)|breast(1)|central_nervous_system(1)	3		Medulloblastoma(188;0.0049)|Breast(177;0.00586)|all_epithelial(84;0.0075)|Ovarian(85;0.0256)|all_neural(188;0.0311)				NSCLC(1;49 61 17205 18850 43201)								0.4	17.04652	17.177825	6	9	CC		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(625;0.00147)|LUSC - Lung squamous cell carcinoma(625;0.191)	Missense_Mutation	SNP	2391307	2391307	17140	11	C	T	T	19	19	TRPM5	T	1	1
MS4A8B	83661	broad.mit.edu	36	11	60227479	60227479	+	Missense_Mutation	SNP	C	T	T			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr11:60227479C>T	uc001npv.1	+	c.272C>T	c.(271-273)GCG>GTG	p.A91V	MS4A8B_uc009yne.1_Missense_Mutation_p.A91V	NM_031457	NP_113645	Q9BY19	M4A8B_HUMAN	membrane-spanning 4-domains, subfamily A, member	91	Helical; (Potential).					integral to membrane	receptor activity				0														0.333333	67.639766	69.550806	26	52	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	60227479	60227479	10260	11	C	T	T	27	27	MS4A8B	T	1	1
HNRNPUL2	221092	broad.mit.edu	36	11	62247728	62247728	+	Silent	SNP	C	G	G			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr11:62247728C>G	uc001nuw.1	-	c.798G>C	c.(796-798)GGG>GGC	p.G266G	HNRNPUL2_uc001nuu.1_Non-coding_Transcript	NM_001079559	NP_001073027	Q1KMD3	HNRL2_HUMAN	heterogeneous nuclear ribonucleoprotein U-like	266	B30.2/SPRY.				cell killing	nucleus	ATP binding|nucleic acid binding				0														0.230769	7.848944	10.724243	9	30	CC		KEEP	---	---	---	---	capture			Silent	SNP	62247728	62247728	7567	11	C	G	G	26	26	HNRNPUL2	G	3	3
MTERFD3	80298	broad.mit.edu	36	12	105896313	105896313	+	Missense_Mutation	SNP	C	T	T			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr12:105896313C>T	uc001tme.1	-	c.310G>A	c.(310-312)GCA>ACA	p.A104T	MTERFD3_uc001tmf.1_Missense_Mutation_p.A104T|MTERFD3_uc001tmg.1_Missense_Mutation_p.A104T|MTERFD3_uc009zus.1_Missense_Mutation_p.A104T|MTERFD3_uc001tmh.1_Missense_Mutation_p.A104T	NM_025198	NP_079474	Q49AM1	MTER3_HUMAN	transcription termination factor-like protein	104					regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrial nucleoid	promoter binding|transcription regulator activity				0														0.142857	13.196131	21.811533	10	60	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	105896313	105896313	10314	12	C	T	T	28	28	MTERFD3	T	2	2
PFKM	5213	broad.mit.edu	36	12	46815409	46815409	+	Silent	SNP	G	A	A			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:46815409G>A	uc001rrb.1	+	c.1125G>A	c.(1123-1125)ACG>ACA	p.T375T	PFKM_uc001rra.1_5'UTR|PFKM_uc001rrc.2_Silent_p.T304T|PFKM_uc001rrd.2_5'UTR|PFKM_uc001rre.1_Silent_p.T304T|PFKM_uc001rrg.1_Intron	NM_000289	NP_000280	P08237	K6PF_HUMAN	phosphofructokinase, muscle	304					fructose 6-phosphate metabolic process|glycolysis|muscle cell homeostasis	6-phosphofructokinase complex|apical plasma membrane	6-phosphofructokinase activity|ATP binding|identical protein binding|kinase binding|metal ion binding|protein C-terminus binding			ovary(1)|kidney(1)	2														0.293103	42.695667	44.893716	17	41	GG		KEEP	---	---	---	---	capture			Silent	SNP	46815409	46815409	12187	12	G	A	A	38	38	PFKM	A	1	1
KCNH3	23416	broad.mit.edu	36	12	48229547	48229547	+	Missense_Mutation	SNP	G	C	C			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:48229547G>C	uc001ruh.1	+	c.1525G>C	c.(1525-1527)GCC>CCC	p.A509P		NM_012284	NP_036416	Q9ULD8	KCNH3_HUMAN	potassium voltage-gated channel, subfamily H	509	Cytoplasmic (Potential).				regulation of transcription, DNA-dependent	integral to membrane	two-component sensor activity|voltage-gated potassium channel activity				0														0.16129	6.570859	9.948791	5	26	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	48229547	48229547	8338	12	G	C	C	38	38	KCNH3	C	3	3
ESPL1	9700	broad.mit.edu	36	12	51949583	51949583	+	Missense_Mutation	SNP	G	T	T			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:51949583G>T	uc001sck.2	+	c.590G>T	c.(589-591)CGA>CTA	p.R197L	ESPL1_uc001scj.2_5'UTR	NM_012291	NP_036423	Q14674	ESPL1_HUMAN	extra spindle poles like 1	197					apoptosis|cytokinesis|establishment of mitotic spindle localization|mitotic sister chromatid segregation|negative regulation of sister chromatid cohesion|positive regulation of mitotic metaphase/anaphase transition|proteolysis	centrosome|nucleus	cysteine-type peptidase activity|protein binding			lung(1)|kidney(1)	2						Colon(53;1069 1201 2587 5382)								0.193798	153.882121	187.775142	75	312	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	51949583	51949583	5446	12	G	T	T	37	37	ESPL1	T	3	3
SP1	6667	broad.mit.edu	36	12	52091163	52091163	+	Missense_Mutation	SNP	A	T	T			TCGA-26-1442-01	TCGA-26-1442-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr12:52091163A>T	uc001scw.1	+	c.2230A>T	c.(2230-2232)ATT>TTT	p.I744F		NM_138473	NP_612482	P08047	SP1_HUMAN	Sp1 transcription factor isoform a	744	Domain D.|VZV IE62-binding.				positive regulation by host of viral transcription|positive regulation of transcription from RNA polymerase II promoter, global	cytoplasm|nucleus	double-stranded DNA binding|histone deacetylase binding|promoter binding|protein C-terminus binding|protein homodimerization activity|RNA polymerase II transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription activator activity|transcription factor binding|zinc ion binding			ovary(1)|breast(1)|skin(1)	3										103				0.127907	15.585297	27.174163	11	75	AA		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(357;0.00527)	Missense_Mutation	SNP	52091163	52091163	15459	12	A	T	T	16	16	SP1	T	4	4
CHD8	57680	broad.mit.edu	36	14	20939960	20939960	+	Missense_Mutation	SNP	G	C	C			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr14:20939960G>C	uc001was.1	-	c.3221C>G	c.(3220-3222)GCT>GGT	p.A1074G	CHD8_uc001war.1_Missense_Mutation_p.A970G|CHD8_uc001wav.1_Missense_Mutation_p.A516G	NM_020920	NP_065971	Q9HCK8	CHD8_HUMAN	chromodomain helicase DNA binding protein 8	1353					ATP-dependent chromatin remodeling|canonical Wnt receptor signaling pathway|chromatin assembly or disassembly|negative regulation of Wnt receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase III promoter|transcription, DNA-dependent	chromatin|MLL1 complex	ATP binding|beta-catenin binding|chromatin binding|DNA binding|DNA helicase activity|DNA-dependent ATPase activity|methylated histone residue binding|p53 binding|transcription activator activity|transcription repressor activity			ovary(6)|upper_aerodigestive_tract(1)|large_intestine(1)|breast(1)|skin(1)	10	all_cancers(95;0.00121)									886				0.133929	28.74503	43.304939	15	97	GG		KEEP	---	---	---	---	capture	Epithelial(56;2.55e-06)|all cancers(55;1.73e-05)	GBM - Glioblastoma multiforme(265;0.00424)	Missense_Mutation	SNP	20939960	20939960	3465	14	G	C	C	34	34	CHD8	C	3	3
DNAH9	1770	broad.mit.edu	36	17	11637571	11637571	+	Silent	SNP	T	C	C			TCGA-26-1442-01	TCGA-26-1442-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr17:11637571T>C	uc002gne.1	+	c.8088T>C	c.(8086-8088)TGT>TGC	p.C2696C	DNAH9_uc010coo.1_Silent_p.C1990C	NM_001372	NP_001363	Q9NYC9	DYH9_HUMAN	dynein, axonemal, heavy chain 9 isoform 2	2696					cell projection organization|cellular component movement|microtubule-based movement|spermatogenesis	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			ovary(4)|breast(3)|central_nervous_system(2)|pancreas(1)	10		Breast(5;0.0122)|all_epithelial(5;0.131)												0.490196	82.044249	82.049098	25	26	TT		KEEP	---	---	---	---	capture		Colorectal(4;6.88e-05)|COAD - Colon adenocarcinoma(4;0.000813)|READ - Rectum adenocarcinoma(10;0.157)	Silent	SNP	11637571	11637571	4791	17	T	C	C	59	59	DNAH9	C	4	4
NR1D1	9572	broad.mit.edu	36	17	35507142	35507142	+	Silent	SNP	T	G	G			TCGA-26-1442-01	TCGA-26-1442-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr17:35507142T>G	uc002htz.1	-	c.72A>C	c.(70-72)CCA>CCC	p.P24P	NR1D1_uc010cwq.1_Non-coding_Transcript|NR1D1_uc010cwr.1_5'Flank	NM_021724	NP_068370	P20393	NR1D1_HUMAN	nuclear receptor subfamily 1, group D, member 1	24					cellular response to lipopolysaccharide|negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of receptor biosynthetic process|negative regulation of toll-like receptor 4 signaling pathway|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	nuclear chromatin|nucleoplasm	promoter binding|steroid hormone receptor activity|transcription corepressor activity|zinc ion binding			skin(1)	1	Colorectal(19;0.000442)													0.461538	7.273815	7.305943	6	7	TT		KEEP	---	---	---	---	capture			Silent	SNP	35507142	35507142	11020	17	T	G	G	63	63	NR1D1	G	4	4
TP53	7157	broad.mit.edu	36	17	7517846	7517846	+	Missense_Mutation	SNP	G	A	A			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr17:7517846G>A	uc002gim.2	-	c.817C>T	c.(817-819)CGT>TGT	p.R273C	TP53_uc002gig.1_Intron|TP53_uc002gih.1_Missense_Mutation_p.R273C|TP53_uc010cne.1_5'Flank|TP53_uc010cnf.1_Missense_Mutation_p.R141C|TP53_uc010cng.1_Missense_Mutation_p.R141C|TP53_uc002gii.1_Missense_Mutation_p.R141C|TP53_uc010cnh.1_Missense_Mutation_p.R273C|TP53_uc010cni.1_Missense_Mutation_p.R273C|TP53_uc002gij.2_Missense_Mutation_p.R273C	NM_001126112	NP_001119584	P04637	P53_HUMAN	tumor protein p53 isoform a	273	Interaction with DNA.||Interaction with E4F1.|Interaction with HIPK1 (By similarity).|Interaction with AXIN1 (By similarity).		R -> N (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions).|R -> S (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> G (in LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> Q (in sporadic cancers; somatic mutation).|R -> Y (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions).|R -> P (in sporadic cancers; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	chromatin|cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|promoter binding|promoter binding|protease binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|sequence-specific DNA binding transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|ubiquitin protein ligase binding|zinc ion binding	p.R273C(388)|p.R273S(11)|p.R273G(9)|p.0?(6)|p.R273fs*72(2)|p.R273fs*33(2)|p.F270fs*72(1)|p.R273_C275delRVC(1)|p.?(1)|p.L265_K305del41(1)|p.S269fs*21(1)|p.E258fs*71(1)|p.C141fs*29(1)|p.R273fs*71(1)|p.F270_D281del12(1)|p.E271_R273delEVR(1)|p.V272_K292del21(1)		large_intestine(4614)|breast(2344)|upper_aerodigestive_tract(2150)|lung(1958)|ovary(1559)|oesophagus(1462)|haematopoietic_and_lymphoid_tissue(1212)|stomach(1127)|urinary_tract(1113)|central_nervous_system(1072)|liver(805)|skin(693)|pancreas(370)|biliary_tract(247)|soft_tissue(209)|prostate(192)|endometrium(150)|bone(102)|vulva(79)|kidney(79)|cervix(68)|thyroid(54)|salivary_gland(41)|adrenal_gland(37)|peritoneum(33)|eye(24)|thymus(21)|genital_tract(16)|autonomic_ganglia(16)|small_intestine(14)|testis(11)|penis(10)|vagina(6)|meninges(5)|pituitary(4)|pleura(3)|gastrointestinal_tract_(site_indeterminate)(1)|NS(1)|Fallopian tube(1)|placenta(1)	21904		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)				Pancreas(47;798 1329 9957 10801)	R273C(SH10TC_STOMACH)|R273C(SUDHL4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273C(8MGBA_CENTRAL_NERVOUS_SYSTEM)|R273C(SW1783_CENTRAL_NERVOUS_SYSTEM)|R273C(BL70_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273C(SW1710_URINARY_TRACT)|R273C(RH30_SOFT_TISSUE)|R273C(PANC0213_PANCREAS)|R273C(SJRH30_SOFT_TISSUE)|R273C(PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273C(RDES_BONE)|R273C(TT2609C02_THYROID)|R273C(MFE319_ENDOMETRIUM)|R273C(RPMI8402_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273C(EFO27_OVARY)|R273C(NCIH1048_LUNG)|R273C(KARPAS299_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)	111	p.R273C(SUDHL4-Tumor)|p.R273C(EFO27-Tumor)|p.R273C(SH10TC-Tumor)|p.R273C(TGBC11TKB-Tumor)|p.R273C(KARPAS299-Tumor)|p.R273C(SW1710-Tumor)|p.R273Y(SNUC2A-Tumor)|p.R273C(TT2609C02-Tumor)|p.R273Y(PF382-Tumor)|p.R273Y(SW1783-Tumor)|p.R273C(RPMI8402-Tumor)|p.R273C(BL70-Tumor)|p.R273C(8305C-Tumor)|p.R273C(SW1088-Tumor)|p.R273C(NCIH1048-Tumor)|p.R273C(SNU1196-Tumor)|p.R273C(CL14-Tumor)|p.R273C(SJRH30-Tumor)|p.R273C(MFE319-Tumor)|p.R273C(PANC02.13-Tumor)|p.R273C(8MGBA-Tumor)	690	TCGA GBM(1;<1E-8)|TSP Lung(2;<1E-8)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			0.529412	25.974267	25.986986	9	8	GG		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)	Missense_Mutation	SNP	7517846	7517846	16923	17	G	A	A	38	38	TP53	A	1	1
SOCS6	9306	broad.mit.edu	36	18	66143476	66143476	+	Missense_Mutation	SNP	A	G	G			TCGA-26-1442-01	TCGA-26-1442-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr18:66143476A>G	uc002lkr.1	+	c.592A>G	c.(592-594)AAT>GAT	p.N198D	SOCS6_uc010dqq.1_Missense_Mutation_p.N198D	NM_004232	NP_004223	O14544	SOCS6_HUMAN	suppressor of cytokine signaling 6	198					defense response|JAK-STAT cascade|negative regulation of signal transduction|regulation of growth	cytoplasm				large_intestine(1)	1		Esophageal squamous(42;0.129)|Colorectal(73;0.152)				Melanoma(84;1024 1361 24382 36583 42651)								0.115942	12.254064	22.268925	8	61	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	66143476	66143476	15418	18	A	G	G	13	13	SOCS6	G	4	4
PGLS	25796	broad.mit.edu	36	19	17487983	17487983	+	Missense_Mutation	SNP	C	T	T			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr19:17487983C>T	uc002ngw.1	+	c.290C>T	c.(289-291)ACG>ATG	p.T97M		NM_012088	NP_036220	O95336	6PGL_HUMAN	6-phosphogluconolactonase	97						cytosol	6-phosphogluconolactonase activity				0														0.382353	33.950961	34.368584	13	21	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	17487983	17487983	12215	19	C	T	T	19	19	PGLS	T	1	1
LMNB2	84823	broad.mit.edu	36	19	2395529	2395529	+	Missense_Mutation	SNP	T	C	C			TCGA-26-1442-01	TCGA-26-1442-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr19:2395529T>C	uc002lwa.1	-	c.274A>G	c.(274-276)ATC>GTC	p.I92V	LMNB2_uc002lvy.1_Missense_Mutation_p.I72V	NM_032737	NP_116126	Q03252	LMNB2_HUMAN	lamin B2	72	Rod.|Linker 1.					nuclear inner membrane	structural molecule activity			large_intestine(1)|ovary(1)	2		Hepatocellular(1079;0.137)								1275				0.184211	15.425025	18.962715	7	31	TT		KEEP	---	---	---	---	capture		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)	Missense_Mutation	SNP	2395529	2395529	9179	19	T	C	C	51	51	LMNB2	C	4	4
PEG3	5178	broad.mit.edu	36	19	62020212	62020212	+	Silent	SNP	G	A	A			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:62020212G>A	uc002qnu.1	-	c.1410C>T	c.(1408-1410)CAC>CAT	p.H470H	ZIM2_uc010etp.1_Intron|ZIM2_uc002qnq.1_Intron|ZIM2_uc002qnr.1_Intron|PEG3_uc002qnt.1_Silent_p.H441H|PEG3_uc002qnv.1_Silent_p.H470H|PEG3_uc010etr.1_Silent_p.H470H|PEG3_uc002qnw.1_Silent_p.H346H|PEG3_uc002qnx.1_Silent_p.H344H	NM_006210	NP_006201	Q9GZU2	PEG3_HUMAN	paternally expressed 3	470	C2H2-type 1.				apoptosis|regulation of transcription, DNA-dependent|viral reproduction	cytoplasm|nucleus	nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(7)|large_intestine(1)|pancreas(1)	9		Colorectal(82;0.000256)|all_neural(62;0.103)|Ovarian(87;0.243)												0.701493	148.728236	151.152665	47	20	GG		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(193;0.0269)	Silent	SNP	62020212	62020212	12141	19	G	A	A	44	44	PEG3	A	2	2
C1orf14	81626	broad.mit.edu	36	1	181187142	181187142	+	Silent	SNP	A	T	T			TCGA-26-1442-01	TCGA-26-1442-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr1:181187142A>T	uc001gpu.1	-	c.489T>A	c.(487-489)ACT>ACA	p.T163T	C1orf14_uc001gpv.1_Silent_p.T44T|C1orf14_uc001gpw.1_5'UTR	NM_030933	NP_112195	Q9BZQ2	SHP1L_HUMAN	chromosome 1 open reading frame 14	235											0														0.365854	40.391528	41.04871	15	26	AA		KEEP	---	---	---	---	capture		Colorectal(1306;1.64e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00267)	Silent	SNP	181187142	181187142	2067	1	A	T	T	15	15	C1orf14	T	4	4
CFHR4	10877	broad.mit.edu	36	1	195153968	195153968	+	Missense_Mutation	SNP	T	C	C			TCGA-26-1442-01	TCGA-26-1442-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr1:195153968T>C	uc001gtp.1	+	c.1546T>C	c.(1546-1548)TGT>CGT	p.C516R	CFHR4_uc001gto.1_Missense_Mutation_p.C269R|CFHR4_uc009wyy.1_Missense_Mutation_p.C515R	NM_006684		Q92496	FHR4_HUMAN	complement factor H-related 4	269	Sushi 5.					extracellular region	lipid transporter activity			ovary(1)|pancreas(1)	2														0.363636	13.197616	13.377341	4	7	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	195153968	195153968	3420	1	T	C	C	51	51	CFHR4	C	4	4
TIE1	7075	broad.mit.edu	36	1	43550720	43550720	+	Silent	SNP	C	T	T			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:43550720C>T	uc001ciu.1	+	c.1788C>T	c.(1786-1788)AAC>AAT	p.N596N	TIE1_uc009vwq.1_Silent_p.N552N	NM_005424	NP_005415	P35590	TIE1_HUMAN	tyrosine kinase with immunoglobulin-like and	596	Fibronectin type-III 2.|Extracellular (Potential).				mesoderm development|protein phosphorylation	integral to plasma membrane	ATP binding|protein binding|transmembrane receptor protein tyrosine kinase activity			stomach(1)|salivary_gland(1)|lung(1)|ovary(1)	4	Acute lymphoblastic leukemia(166;0.155)	Myeloproliferative disorder(586;0.0505)								488				0.275862	17.774958	19.098175	8	21	CC		KEEP	---	---	---	---	capture			Silent	SNP	43550720	43550720	16421	1	C	T	T	19	19	TIE1	T	1	1
ACOT8	10005	broad.mit.edu	36	20	43910655	43910655	+	Missense_Mutation	SNP	C	T	T			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr20:43910655C>T	uc002xqa.1	-	c.329G>A	c.(328-330)CGC>CAC	p.R110H	ACOT8_uc002xqb.1_Missense_Mutation_p.R110H|ACOT8_uc002xqc.1_Missense_Mutation_p.R57H	NM_005469	NP_005460	O14734	ACOT8_HUMAN	peroxisomal acyl-CoA thioesterase 1 isoform a	110					bile acid biosynthetic process|fatty acid beta-oxidation using acyl-CoA oxidase|interspecies interaction between organisms|peroxisome organization	peroxisomal matrix	acetyl-CoA hydrolase activity|acyl-CoA thioesterase activity|carboxylesterase activity|choloyl-CoA hydrolase activity|protein binding				0		Myeloproliferative disorder(115;0.0122)												0.165049	28.534335	39.488316	17	86	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	43910655	43910655	157	20	C	T	T	27	27	ACOT8	T	1	1
KIF5C	3800	broad.mit.edu	36	2	149565492	149565492	+	Missense_Mutation	SNP	G	C	C			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr2:149565492G>C	uc002twr.1	+	c.2323G>C	c.(2323-2325)GAT>CAT	p.D775H	KIF5C_uc002tws.1_Non-coding_Transcript|KIF5C_uc002twu.1_Missense_Mutation_p.D57H	NM_004522	NP_004513	O60282	KIF5C_HUMAN	kinesin family member 5C	775					microtubule-based movement|organelle organization	cytoplasm|kinesin complex|microtubule	ATP binding|microtubule motor activity			skin(1)	1														0.323529	67.533892	69.409821	22	46	GG		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(221;0.108)	Missense_Mutation	SNP	149565492	149565492	8618	2	G	C	C	37	37	KIF5C	C	3	3
COQ10B	80219	broad.mit.edu	36	2	198026613	198026613	+	Silent	SNP	G	A	A			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr2:198026613G>A	uc002uuh.1	+	c.84G>A	c.(82-84)CAG>CAA	p.Q28Q	COQ10B_uc010fsl.1_5'Flank	NM_025147	NP_079423	Q9H8M1	CQ10B_HUMAN	coenzyme Q10 homolog B	28						mitochondrial inner membrane					0														0.327586	52.805948	54.334568	19	39	GG		KEEP	---	---	---	---	capture	Epithelial(96;0.231)|OV - Ovarian serous cystadenocarcinoma(117;0.246)		Silent	SNP	198026613	198026613	3882	2	G	A	A	35	35	COQ10B	A	2	2
IDH1	3417	broad.mit.edu	36	2	208821357	208821357	+	Missense_Mutation	SNP	C	T	T			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:208821357C>T	uc002vcs.1	-	c.395G>A	c.(394-396)CGT>CAT	p.R132H	IDH1_uc002vct.1_Missense_Mutation_p.R132H|IDH1_uc002vcu.1_Missense_Mutation_p.R132H	NM_005896	NP_005887	O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132		Substrate.	R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(1725)|p.R132?(210)|p.R132C(92)|p.R132L(48)|p.R132G(26)|p.R132S(11)|p.R132V(1)|p.G131_R132>VL(1)		central_nervous_system(1848)|haematopoietic_and_lymphoid_tissue(593)|large_intestine(4)|skin(2)|prostate(2)|autonomic_ganglia(1)|soft_tissue(1)	2451						Pancreas(158;264 1958 3300 35450 36047)				134				0.5625	56.554978	56.664354	18	14	CC		KEEP	---	---	---	---	capture		Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)	Missense_Mutation	SNP	208821357	208821357	7794	2	C	T	T	19	19	IDH1	T	1	1
CHPF	79586	broad.mit.edu	36	2	220114630	220114630	+	Silent	SNP	A	C	C			TCGA-26-1442-01	TCGA-26-1442-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr2:220114630A>C	uc002vmc.2	-	c.840T>G	c.(838-840)GGT>GGG	p.G280G	CHPF_uc002vmd.2_Silent_p.G280G|TMEM198_uc002vme.1_5'Flank|TMEM198_uc002vmf.1_5'Flank	NM_024536	NP_078812	Q8IZ52	CHSS2_HUMAN	chondroitin polymerizing factor	280	Lumenal (Potential).					Golgi cisterna membrane|integral to membrane	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|metal ion binding|N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity|protein binding				0		Renal(207;0.0183)										OREG0015229	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.3	7.020674	7.378364	3	7	AA		KEEP	---	---	---	---	capture		Epithelial(149;3.02e-08)|all cancers(144;3.41e-06)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00802)	Silent	SNP	220114630	220114630	3502	2	A	C	C	10	10	CHPF	C	4	4
TTC27	55622	broad.mit.edu	36	2	32889765	32889765	+	Missense_Mutation	SNP	G	C	C			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr2:32889765G>C	uc002rom.1	+	c.2169G>C	c.(2167-2169)CAG>CAC	p.Q723H	TTC27_uc002ron.1_Non-coding_Transcript	NM_017735	NP_060205	Q6P3X3	TTC27_HUMAN	tetratricopeptide repeat domain 27	723							protein binding			central_nervous_system(1)	1														0.210526	10.889179	12.362019	4	15	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	32889765	32889765	17249	2	G	C	C	33	33	TTC27	C	3	3
DZIP1L	199221	broad.mit.edu	36	3	139282106	139282106	+	Silent	SNP	T	C	C			TCGA-26-1442-01	TCGA-26-1442-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr3:139282106T>C	uc003erq.1	-	c.1281A>G	c.(1279-1281)CCA>CCG	p.P427P	DZIP1L_uc003err.1_Silent_p.P427P	NM_173543	NP_775814	Q8IYY4	DZI1L_HUMAN	DAZ interacting protein 1-like	427						intracellular	zinc ion binding			ovary(1)|pancreas(1)	2														0.5	80.474621	80.474621	25	25	TT		KEEP	---	---	---	---	capture			Silent	SNP	139282106	139282106	5050	3	T	C	C	55	55	DZIP1L	C	4	4
ZBTB38	253461	broad.mit.edu	36	3	142645653	142645653	+	Missense_Mutation	SNP	A	G	G			TCGA-26-1442-01	TCGA-26-1442-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr3:142645653A>G	uc003etw.1	+	c.1733A>G	c.(1732-1734)TAT>TGT	p.Y578C	ZBTB38_uc010hun.1_Missense_Mutation_p.Y575C|ZBTB38_uc010huo.1_Missense_Mutation_p.Y578C|ZBTB38_uc003ety.1_Missense_Mutation_p.Y578C|ZBTB38_uc010hup.1_Missense_Mutation_p.Y578C	NM_001080412	NP_001073881	Q8NAP3	ZBT38_HUMAN	zinc finger and BTB domain containing 38	578					positive regulation of transcription from RNA polymerase II promoter	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(3)	3														0.138462	17.271617	25.450307	9	56	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	142645653	142645653	18125	3	A	G	G	16	16	ZBTB38	G	4	4
ITIH1	3697	broad.mit.edu	36	3	52797122	52797122	+	Missense_Mutation	SNP	G	A	A			TCGA-26-1442-01	TCGA-26-1442-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr3:52797122G>A	uc003dfs.2	+	c.2005G>A	c.(2005-2007)GTG>ATG	p.V669M	ITIH1_uc010hmn.1_Non-coding_Transcript|ITIH1_uc003dft.2_Missense_Mutation_p.V270M|ITIH1_uc010hmo.1_Missense_Mutation_p.V223M|ITIH1_uc003dfu.2_Missense_Mutation_p.V35M	NM_002215	NP_002206	P19827	ITIH1_HUMAN	inter-alpha (globulin) inhibitor H1	669	Hyaluronan-binding.				hyaluronan metabolic process|leukocyte activation	extracellular region	calcium ion binding|serine-type endopeptidase inhibitor activity			ovary(3)	3														0.227848	45.11361	50.478864	18	61	GG		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(193;7.04e-05)|Kidney(197;0.000659)|KIRC - Kidney renal clear cell carcinoma(197;0.000795)|OV - Ovarian serous cystadenocarcinoma(275;0.0498)	Missense_Mutation	SNP	52797122	52797122	8207	3	G	A	A	39	39	ITIH1	A	1	1
MFSD10	10227	broad.mit.edu	36	4	2905146	2905146	+	Missense_Mutation	SNP	C	A	A			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr4:2905146C>A	uc003gfw.1	-	c.214G>T	c.(214-216)GCC>TCC	p.A72S	MFSD10_uc003gfv.1_5'Flank|MFSD10_uc003gfx.1_5'UTR|MFSD10_uc003gfy.1_Non-coding_Transcript|MFSD10_uc003gfz.1_Missense_Mutation_p.A72S|MFSD10_uc003gga.1_Missense_Mutation_p.A72S|MFSD10_uc003ggb.1_Missense_Mutation_p.A72S|MFSD10_uc003ggc.1_Missense_Mutation_p.A72S|C4orf10_uc003ggd.1_5'Flank|C4orf10_uc003gge.1_5'Flank|C4orf10_uc003ggg.1_5'Flank|C4orf10_uc003ggh.2_5'Flank	NM_001120	NP_001111	Q14728	MFS10_HUMAN	major facilitator superfamily domain containing	72					apoptosis	integral to membrane	tetracycline transporter activity				0														0.185185	8.860977	11.369423	5	22	CC		KEEP	---	---	---	---	capture		UCEC - Uterine corpus endometrioid carcinoma (64;0.163)	Missense_Mutation	SNP	2905146	2905146	9918	4	C	A	A	25	25	MFSD10	A	3	3
TNRC18	84629	broad.mit.edu	36	7	5321140	5321140	+	Splice_Site_SNP	SNP	C	A	A			TCGA-26-1442-01	TCGA-26-1442-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr7:5321140C>A	uc003soi.2	-	c.7027_splice	c.e26+1	p.D2343_splice		NM_001080495	NP_001073964			trinucleotide repeat containing 18								DNA binding				0		Ovarian(82;0.142)												0.444444	12.399179	12.423318	4	5	CC		KEEP	---	---	---	---	capture		UCEC - Uterine corpus endometrioid carcinoma (126;0.195)|OV - Ovarian serous cystadenocarcinoma(56;5.32e-15)	Splice_Site_SNP	SNP	5321140	5321140	16880	7	C	A	A	18	18	TNRC18	A	5	3
C9orf79	286234	broad.mit.edu	36	9	89689770	89689770	+	Missense_Mutation	SNP	A	G	G			TCGA-26-1442-01	TCGA-26-1442-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr9:89689770A>G	uc004app.2	+	c.548A>G	c.(547-549)GAT>GGT	p.D183G	C9orf79_uc004apo.1_Intron	NM_178828	NP_849150	Q6ZUB1	CI079_HUMAN	chromosome 9 open reading frame 79	183	Pro-rich.					integral to membrane				ovary(3)	3														0.108911	11.799647	27.062141	11	90	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	89689770	89689770	2613	9	A	G	G	12	12	C9orf79	G	4	4
AK1	203	broad.mit.edu	36	9	129670511	129670512	+	Frame_Shift_Ins	INS	-	T	T			TCGA-26-1442-01	TCGA-26-1442-01										Phase_I	Unspecified				Illumina GAIIx	g.chr9:129670511_129670512insT	uc004bsm.2	-	c.425_426insA	c.(424-426)AATfs	p.N142fs		NM_000476	NP_000467	P00568	KAD1_HUMAN	adenylate kinase 1	142					ATP metabolic process|nucleobase, nucleoside and nucleotide interconversion	cytosol	adenylate kinase activity|ATP binding|protein binding				0														0.37			13	22				---	---	---	---	capture_indel			Frame_Shift_Ins	INS	129670511	129670512	442	9	-	T	T	8	8	AK1	T	5	5
