Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Genome_Change	Annotation_Transcript	Transcript_Strand	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	i_TCGAscape_Amplification_Peaks	i_TCGAscape_Deletion_Peaks	DrugBank	i_ACHILLES_Top_Genes	i_CCLE_ONCOMAP_overlapping_mutations	i_CCLE_ONCOMAP_total_mutations_in_gene	i_CCLE_SEQ_overlapping_mutations	i_CCLE_SEQ_total_mutations_in_gene	MUTSIG_Significant_Genes	OREGANNO_ID	OREGANNO_Values	i_tumor_f	i_init_t_lod	i_t_lod_fstar	i_t_alt_count	i_t_ref_count	i_normal_best_gt	i_failure_reasons	i_judgement	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	dataset	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	type	classification	start	end	gene	chr	ref_allele	tum_allele1	tum_allele2	context_orig	context65	gene_name	newbase	categ	categ_ignoring_null_categ
NOC3L	64318	broad.mit.edu	36	10	96089649	96089649	+	Missense_Mutation	SNP	A	G	G			TCGA-26-5134-01	TCGA-26-5134-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr10:96089649A>G	uc001kjq.1	-	c.1799T>C	c.(1798-1800)GTT>GCT	p.V600A		NM_022451	NP_071896	Q8WTT2	NOC3L_HUMAN	nucleolar complex associated 3 homolog	600						nuclear speck|nucleolus	binding			ovary(1)	1		Colorectal(252;0.0897)												0.894737	198.270203	207.102127	51	6	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	96089649	96089649	10917	10	A	G	G	2	2	NOC3L	G	4	4
OR8D4	338662	broad.mit.edu	36	11	123282583	123282583	+	Missense_Mutation	SNP	C	A	A			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr11:123282583C>A	uc001pzj.1	+	c.235C>A	c.(235-237)CCT>ACT	p.P79T		NM_001005197	NP_001005197	Q8NGM9	OR8D4_HUMAN	olfactory receptor, family 8, subfamily D,	79	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity				0		Breast(109;0.00867)|Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|all_neural(223;0.22)												0.44879	721.131787	722.367424	241	296	CC		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(274;4.93e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0409)	Missense_Mutation	SNP	123282583	123282583	11644	11	C	A	A	22	22	OR8D4	A	3	3
VSIG2	23584	broad.mit.edu	36	11	124123561	124123561	+	Silent	SNP	G	A	A			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr11:124123561G>A	uc001qas.1	-	c.786C>T	c.(784-786)TGC>TGT	p.C262C	VSIG2_uc001qat.2_Silent_p.C262C	NM_014312	NP_055127	Q96IQ7	VSIG2_HUMAN	V-set and immunoglobulin domain containing 2	262	Helical; (Potential).					integral to plasma membrane|membrane fraction				ovary(3)|central_nervous_system(1)	4	all_hematologic(175;0.215)	Breast(109;0.00663)|Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|all_neural(223;0.224)												0.429412	206.639487	207.379618	73	97	GG		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(274;1.49e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0215)	Silent	SNP	124123561	124123561	17792	11	G	A	A	42	42	VSIG2	A	2	2
OR4A16	81327	broad.mit.edu	36	11	54867844	54867844	+	Missense_Mutation	SNP	G	T	T			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr11:54867844G>T	uc001nhm.1	+	c.592G>T	c.(592-594)GTT>TTT	p.V198F		NM_001005274	NP_001005274	Q8NH70	O4A16_HUMAN	olfactory receptor, family 4, subfamily A,	198	Helical; Name=5; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			large_intestine(2)|pancreas(1)	3														0.429752	494.158502	495.716076	156	207	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	54867844	54867844	11447	11	G	T	T	44	44	OR4A16	T	3	3
OR5I1	10798	broad.mit.edu	36	11	55460161	55460161	+	Missense_Mutation	SNP	C	A	A			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr11:55460161C>A	uc001nic.1	-	c.292G>T	c.(292-294)GGG>TGG	p.G98W		NM_006637	NP_006628	Q13606	OR5I1_HUMAN	olfactory receptor, family 5, subfamily I,	98	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)	1														0.416667	89.436728	89.873371	30	42	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	55460161	55460161	11574	11	C	A	A	21	21	OR5I1	A	3	3
C11orf2	738	broad.mit.edu	36	11	64632727	64632727	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr11:64632727C>T	uc001ocr.1	+	c.1208C>T	c.(1207-1209)GCC>GTC	p.A403V	C11orf2_uc001ocs.1_Missense_Mutation_p.A279V	NM_013265	NP_037397	Q9UID3	FFR_HUMAN	chromosome 11 open reading frame2	403					lipid transport|protein transport	Golgi apparatus|integral to membrane					0														0.52381	31.725881	31.736332	11	10	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	64632727	64632727	1670	11	C	T	T	26	26	C11orf2	T	2	2
LRRC43	254050	broad.mit.edu	36	12	121238328	121238328	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr12:121238328C>T	uc009zxm.1	+	c.650C>T	c.(649-651)ACC>ATC	p.T217I	LRRC43_uc001ubw.2_Missense_Mutation_p.T32I|LRRC43_uc009zxn.1_5'Flank|LRRC43_uc009zxl.1_Non-coding_Transcript	NM_001098519	NP_001091989	Q8N309	LRC43_HUMAN	leucine rich repeat containing 43 isoform 1	217											0	all_neural(191;0.0837)|Medulloblastoma(191;0.163)													0.369697	176.531896	178.993929	61	104	CC		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(86;0.000312)|Epithelial(86;0.000539)|BRCA - Breast invasive adenocarcinoma(302;0.225)	Missense_Mutation	SNP	121238328	121238328	9376	12	C	T	T	18	18	LRRC43	T	2	2
CD163L1	283316	broad.mit.edu	36	12	7418759	7418759	+	Missense_Mutation	SNP	C	A	A			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr12:7418759C>A	uc001qsy.1	-	c.3029G>T	c.(3028-3030)TGC>TTC	p.C1010F		NM_174941	NP_777601	Q9NR16	C163B_HUMAN	scavenger receptor cysteine-rich type 1	1010	Extracellular (Potential).					extracellular region|integral to membrane|plasma membrane	scavenger receptor activity			ovary(8)|central_nervous_system(1)	9												OREG0021653	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.329114	73.720514	75.766982	26	53	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	7418759	7418759	3095	12	C	A	A	25	25	CD163L1	A	3	3
NBEA	26960	broad.mit.edu	36	13	34583025	34583025	+	Missense_Mutation	SNP	G	C	C			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr13:34583025G>C	uc001uvb.1	+	c.1912G>C	c.(1912-1914)GGA>CGA	p.G638R		NM_015678	NP_056493	Q8NFP9	NBEA_HUMAN	neurobeachin	638						cytosol|endomembrane system|plasma membrane|trans-Golgi network	protein binding			ovary(9)|large_intestine(2)	11		Breast(139;0.0141)|Lung SC(185;0.0548)|Prostate(109;0.207)												0.383929	137.196235	138.520171	43	69	GG		KEEP	---	---	---	---	capture		all cancers(112;1.93e-08)|Epithelial(112;1.62e-07)|BRCA - Breast invasive adenocarcinoma(63;0.00033)|OV - Ovarian serous cystadenocarcinoma(117;0.00109)|KIRC - Kidney renal clear cell carcinoma(186;0.00575)|Kidney(163;0.00656)|GBM - Glioblastoma multiforme(144;0.191)|Lung(94;0.199)	Missense_Mutation	SNP	34583025	34583025	10583	13	G	C	C	35	35	NBEA	C	3	3
AHNAK2	113146	broad.mit.edu	36	14	104486613	104486613	+	Missense_Mutation	SNP	C	G	G			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr14:104486613C>G	uc010axc.1	-	c.6220G>C	c.(6220-6222)GTG>CTG	p.V2074L	AHNAK2_uc001ypx.2_Missense_Mutation_p.V1974L	NM_138420	NP_612429	Q8IVF2	AHNK2_HUMAN	AHNAK nucleoprotein 2	2074						nucleus				ovary(1)	1		all_cancers(154;0.115)|Melanoma(154;0.155)|all_epithelial(191;0.183)												1	8.77727	8.554105	2	0	CC		KEEP	---	---	---	---	capture	all cancers(16;0.000479)|OV - Ovarian serous cystadenocarcinoma(23;0.00659)|Epithelial(46;0.0151)|GBM - Glioblastoma multiforme(11;0.116)		Missense_Mutation	SNP	104486613	104486613	418	14	C	G	G	18	18	AHNAK2	G	3	3
OR4K2	390431	broad.mit.edu	36	14	19414697	19414697	+	Missense_Mutation	SNP	T	C	C			TCGA-26-5134-01	TCGA-26-5134-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr14:19414697T>C	uc001vwh.1	+	c.431T>C	c.(430-432)CTC>CCC	p.L144P		NM_001005501	NP_001005501	Q8NGD2	OR4K2_HUMAN	olfactory receptor, family 4, subfamily K,	144	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)	2	all_cancers(95;0.00108)													0.389011	604.169172	609.08048	177	278	TT		KEEP	---	---	---	---	capture	Epithelial(56;9.96e-07)|all cancers(55;2.95e-06)	GBM - Glioblastoma multiforme(265;0.00327)	Missense_Mutation	SNP	19414697	19414697	11482	14	T	C	C	54	54	OR4K2	C	4	4
PCNX	22990	broad.mit.edu	36	14	70610140	70610140	+	Nonsense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr14:70610140C>T	uc001xmo.2	+	c.4978C>T	c.(4978-4980)CGA>TGA	p.R1660*	PCNX_uc010are.1_Nonsense_Mutation_p.R1549*|PCNX_uc010arf.1_Nonsense_Mutation_p.R448*	NM_014982	NP_055797	Q96RV3	PCX1_HUMAN	pecanex-like 1	1660						integral to membrane				ovary(1)	1														0.807143	367.647495	379.977529	113	27	CC		KEEP	---	---	---	---	capture	KIRC - Kidney renal clear cell carcinoma(12;0.206)	all cancers(60;0.00835)|BRCA - Breast invasive adenocarcinoma(234;0.00951)|OV - Ovarian serous cystadenocarcinoma(108;0.0417)	Nonsense_Mutation	SNP	70610140	70610140	12011	14	C	T	T	27	27	PCNX	T	5	1
EML5	161436	broad.mit.edu	36	14	88238558	88238558	+	Silent	SNP	G	A	A			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr14:88238558G>A	uc001xxg.1	-	c.2223C>T	c.(2221-2223)TAC>TAT	p.Y741Y	EML5_uc001xxh.1_De_novo_Start_OutOfFrame	NM_183387	NP_899243	Q05BV3	EMAL5_HUMAN	echinoderm microtubule associated protein like	741	WD 11.					cytoplasm|microtubule				ovary(3)	3														0.842105	107.723353	111.963743	32	6	GG		KEEP	---	---	---	---	capture			Silent	SNP	88238558	88238558	5292	14	G	A	A	40	40	EML5	A	1	1
PAPD5	64282	broad.mit.edu	36	16	48820618	48820618	+	Missense_Mutation	SNP	C	G	G			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr16:48820618C>G	uc002ega.1	+	c.1348C>G	c.(1348-1350)CAA>GAA	p.Q450E	PAPD5_uc010cbi.1_Intron|PAPD5_uc002efz.1_Missense_Mutation_p.Q403E	NM_001040284	NP_001035374	Q8NDF8	PAPD5_HUMAN	PAP associated domain containing 5 isoform a	533					cell division|DNA replication|histone mRNA catabolic process|mitosis	cytoplasm|nucleus	DNA binding|DNA-directed DNA polymerase activity				0		all_cancers(37;0.0452)												0.542857	206.306827	206.479071	57	48	CC		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(181;0.0843)|GBM - Glioblastoma multiforme(240;0.231)	Missense_Mutation	SNP	48820618	48820618	11842	16	C	G	G	29	29	PAPD5	G	3	3
INPP5K	51763	broad.mit.edu	36	17	1366517	1366517	+	Silent	SNP	C	G	G			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr17:1366517C>G	uc002fsr.1	-	c.27G>C	c.(25-27)CCG>CCC	p.P9P	INPP5K_uc002fsq.1_5'UTR|INPP5K_uc002fss.1_5'UTR|INPP5K_uc010cjr.1_5'UTR|INPP5K_uc010cjs.1_Silent_p.P9P	NM_016532	NP_570122	Q9BT40	INP5K_HUMAN	inositol polyphosphate-5-phosphatase K isoform	9					actin cytoskeleton organization	cytosol|endoplasmic reticulum|membrane fraction|neuron projection|ruffle	inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity|inositol bisphosphate phosphatase activity|inositol bisphosphate phosphatase activity|inositol trisphosphate phosphatase activity|inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol-polyphosphate 5-phosphatase activity|lipid phosphatase activity|protein binding				0														0.48	38.59963	38.608234	12	13	CC		KEEP	---	---	---	---	capture			Silent	SNP	1366517	1366517	8061	17	C	G	G	31	31	INPP5K	G	3	3
PHF12	57649	broad.mit.edu	36	17	24258093	24258093	+	Missense_Mutation	SNP	T	C	C			TCGA-26-5134-01	TCGA-26-5134-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr17:24258093T>C	uc002hdg.1	-	c.2587A>G	c.(2587-2589)ACG>GCG	p.T863A		NM_001033561	NP_001028733	Q96QT6	PHF12_HUMAN	PHD finger protein 12 isoform 1	863	FHA.				negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	transcriptional repressor complex	protein binding|transcription repressor activity|zinc ion binding			ovary(1)	1	all_cancers(5;1.95e-14)|all_epithelial(6;5e-18)|Lung NSC(42;0.01)													0.452941	536.629257	537.293984	154	186	TT		KEEP	---	---	---	---	capture	Epithelial(11;1.64e-05)|all cancers(11;7.47e-05)|BRCA - Breast invasive adenocarcinoma(11;9.79e-05)		Missense_Mutation	SNP	24258093	24258093	12246	17	T	C	C	60	60	PHF12	C	4	4
DSG3	1830	broad.mit.edu	36	18	27306355	27306355	+	Missense_Mutation	SNP	G	A	A			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr18:27306355G>A	uc002kws.1	+	c.2008G>A	c.(2008-2010)GGA>AGA	p.G670R	DSG3_uc002kwt.1_5'Flank	NM_001944	NP_001935	P32926	DSG3_HUMAN	desmoglein 3 preproprotein	670	Cytoplasmic (Potential).				cellular component disassembly involved in apoptosis|homophilic cell adhesion	cytosol|desmosome|integral to membrane	calcium ion binding			ovary(3)|lung(1)|central_nervous_system(1)	5														0.436975	167.485797	167.897321	52	67	GG		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(10;0.00504)		Missense_Mutation	SNP	27306355	27306355	4962	18	G	A	A	43	43	DSG3	A	2	2
TYK2	7297	broad.mit.edu	36	19	10324654	10324654	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr19:10324654C>T	uc002moc.2	-	c.3148G>A	c.(3148-3150)GAA>AAA	p.E1050K	TYK2_uc010dxe.1_Missense_Mutation_p.E865K	NM_003331	NP_003322	P29597	TYK2_HUMAN	tyrosine kinase 2	1050	Protein kinase 2.				intracellular protein kinase cascade|protein phosphorylation|regulation of type I interferon-mediated signaling pathway|type I interferon-mediated signaling pathway	cytoskeleton|cytosol|membrane|nucleus	ATP binding|growth hormone receptor binding|non-membrane spanning protein tyrosine kinase activity			large_intestine(2)|lung(2)|breast(1)	5										414				0.375	74.755956	75.724099	27	45	CC		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(20;1.77e-09)|Epithelial(33;3.92e-06)|all cancers(31;8.95e-06)		Missense_Mutation	SNP	10324654	10324654	17367	19	C	T	T	31	31	TYK2	T	1	1
JAK3	3718	broad.mit.edu	36	19	17815220	17815220	+	Missense_Mutation	SNP	T	G	G			TCGA-26-5134-01	TCGA-26-5134-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr19:17815220T>G	uc002nhn.2	-	c.389A>C	c.(388-390)GAC>GCC	p.D130A	JAK3_uc010ebh.1_Non-coding_Transcript|JAK3_uc002nho.2_Missense_Mutation_p.D130A	NM_000215	NP_000206	P52333	JAK3_HUMAN	Janus kinase 3	130	FERM.				B cell differentiation|cytokine-mediated signaling pathway|enzyme linked receptor protein signaling pathway|intracellular protein kinase cascade|negative regulation of dendritic cell cytokine production|negative regulation of FasL biosynthetic process|negative regulation of interleukin-10 production|negative regulation of interleukin-12 production|negative regulation of T-helper 1 cell differentiation|negative regulation of thymocyte apoptosis|peptidyl-tyrosine phosphorylation|positive regulation of anti-apoptosis|response to interleukin-15|response to interleukin-2|response to interleukin-4|response to interleukin-9|T cell homeostasis	cytoskeleton|cytosol|endomembrane system|membrane	ATP binding|non-membrane spanning protein tyrosine kinase activity|protein binding			haematopoietic_and_lymphoid_tissue(36)|lung(3)|ovary(3)|stomach(2)|breast(2)	46								2		364				0.285714	7.574638	8.169506	4	10	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	17815220	17815220	8243	19	T	G	G	58	58	JAK3	G	4	4
S1PR4	8698	broad.mit.edu	36	19	3130828	3130828	+	Silent	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr19:3130828C>T	uc002lxg.1	+	c.1038C>T	c.(1036-1038)TCC>TCT	p.S346S		NM_003775	NP_003766	O95977	S1PR4_HUMAN	sphingosine-1-phosphate receptor 4 precursor	346	Cytoplasmic (By similarity).				activation of phospholipase C activity|elevation of cytosolic calcium ion concentration|immune response	integral to plasma membrane	lipid binding|lysosphingolipid and lysophosphatidic acid receptor activity				0						GBM(82;318 1638 33279 49708)								0.45283	291.042621	291.440907	96	116	CC		KEEP	---	---	---	---	capture			Silent	SNP	3130828	3130828	14276	19	C	T	T	23	23	S1PR4	T	1	1
ZNF540	163255	broad.mit.edu	36	19	42795530	42795530	+	Silent	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr19:42795530C>T	uc002ogq.1	+	c.1509C>T	c.(1507-1509)ACC>ACT	p.T503T	ZNF540_uc002ogu.1_Silent_p.T503T|ZNF540_uc010efq.1_Silent_p.T471T	NM_152606	NP_689819	Q8NDQ6	ZN540_HUMAN	zinc finger protein 540	503	C2H2-type 12.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			large_intestine(1)	1														0.39823	287.601324	289.649966	90	136	CC		KEEP	---	---	---	---	capture	COAD - Colon adenocarcinoma(19;0.114)|Colorectal(19;0.177)		Silent	SNP	42795530	42795530	18569	19	C	T	T	24	24	ZNF540	T	2	2
CD33	945	broad.mit.edu	36	19	56420387	56420387	+	Missense_Mutation	SNP	A	T	T			TCGA-26-5134-01	TCGA-26-5134-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr19:56420387A>T	uc002pwa.2	+	c.139A>T	c.(139-141)ATA>TTA	p.I47L	CD33_uc010eos.1_Missense_Mutation_p.I47L|CD33_uc010eot.1_Intron|CD33_uc010eou.1_5'Flank	NM_001772	NP_001763	P20138	CD33_HUMAN	CD33 antigen isoform 1 precursor	47	Extracellular (Potential).|Ig-like V-type.				cell adhesion|cell-cell signaling|negative regulation of cell proliferation	integral to plasma membrane	receptor activity|sugar binding				0		all_neural(266;0.0199)			Gemtuzumab ozogamicin(DB00056)									0.413174	221.852577	222.94999	69	98	AA		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(134;0.000224)|OV - Ovarian serous cystadenocarcinoma(262;0.00468)	Missense_Mutation	SNP	56420387	56420387	3133	19	A	T	T	8	8	CD33	T	4	4
HRNR	388697	broad.mit.edu	36	1	150452391	150452391	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:150452391C>T	uc001ezt.1	-	c.8338G>A	c.(8338-8340)GGG>AGG	p.G2780R		NM_001009931	NP_001009931	Q86YZ3	HORN_HUMAN	hornerin	2780	30.				keratinization		calcium ion binding|protein binding			ovary(1)	1	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)													0.25	11.732529	13.102074	6	18	CC		KEEP	---	---	---	---	capture	LUSC - Lung squamous cell carcinoma(543;0.206)		Missense_Mutation	SNP	150452391	150452391	7653	1	C	T	T	24	24	HRNR	T	2	2
GALE	2582	broad.mit.edu	36	1	23996115	23996115	+	Missense_Mutation	SNP	G	A	A			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:23996115G>A	uc009vqo.1	-	c.638C>T	c.(637-639)TCC>TTC	p.S213F	GALE_uc001bhv.1_Missense_Mutation_p.S213F|GALE_uc001bhw.1_Missense_Mutation_p.S213F|GALE_uc001bhx.1_Missense_Mutation_p.S213F|GALE_uc009vqp.1_Missense_Mutation_p.S213F|GALE_uc001bhy.1_Missense_Mutation_p.S213F|GALE_uc001bhz.1_Missense_Mutation_p.S139F|GALE_uc001bia.1_Missense_Mutation_p.S5F	NM_001127621	NP_001121093	Q14376	GALE_HUMAN	UDP-galactose-4-epimerase	213					galactose catabolic process	cytosol	coenzyme binding|protein homodimerization activity|UDP-glucose 4-epimerase activity				0		Colorectal(325;3.46e-05)|Renal(390;0.000219)|Lung NSC(340;0.000233)|all_lung(284;0.000321)|Breast(348;0.0044)|Ovarian(437;0.00539)|Myeloproliferative disorder(586;0.0255)				Colon(17;142 583 2667 10036 24961)								0.405405	46.22366	46.511238	15	22	GG		KEEP	---	---	---	---	capture		UCEC - Uterine corpus endometrioid carcinoma (279;0.0227)|OV - Ovarian serous cystadenocarcinoma(117;1.79e-24)|Colorectal(126;4.8e-08)|COAD - Colon adenocarcinoma(152;2.83e-06)|GBM - Glioblastoma multiforme(114;4.22e-06)|BRCA - Breast invasive adenocarcinoma(304;0.000946)|KIRC - Kidney renal clear cell carcinoma(1967;0.00314)|STAD - Stomach adenocarcinoma(196;0.0123)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.0827)|LUSC - Lung squamous cell carcinoma(448;0.184)	Missense_Mutation	SNP	23996115	23996115	6466	1	G	A	A	41	41	GALE	A	2	2
MFSD2A	84879	broad.mit.edu	36	1	40204210	40204210	+	Silent	SNP	T	C	C			TCGA-26-5134-01	TCGA-26-5134-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr1:40204210T>C	uc001cev.1	+	c.690T>C	c.(688-690)AAT>AAC	p.N230N	MFSD2A_uc001ceu.1_Silent_p.N217N|MFSD2A_uc009vvy.1_Non-coding_Transcript|MFSD2A_uc001cex.1_5'Flank	NM_032793	NP_116182	Q8NA29	MFS2A_HUMAN	major facilitator superfamily domain containing	230					transmembrane transport	endoplasmic reticulum membrane|integral to membrane				ovary(1)|pancreas(1)	2										141				0.352113	170.324379	173.055908	50	92	TT		KEEP	---	---	---	---	capture			Silent	SNP	40204210	40204210	9920	1	T	C	C	49	49	MFSD2A	C	4	4
CYP4Z1	199974	broad.mit.edu	36	1	47356089	47356089	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:47356089C>T	uc001cqu.1	+	c.1414C>T	c.(1414-1416)CGC>TGC	p.R472C		NM_178134	NP_835235	Q86W10	CP4Z1_HUMAN	cytochrome P450 4Z1	472	Lumenal (Potential).				oxidation-reduction process	endoplasmic reticulum membrane|integral to membrane|microsome	aromatase activity|electron carrier activity|heme binding				0														0.45	165.335945	165.596856	54	66	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	47356089	47356089	4359	1	C	T	T	23	23	CYP4Z1	T	1	1
PXMP4	11264	broad.mit.edu	36	20	31771667	31771667	+	Missense_Mutation	SNP	G	C	C			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr20:31771667G>C	uc002wzv.1	-	c.8C>G	c.(7-9)GCC>GGC	p.A3G	PXMP4_uc002wzw.1_Missense_Mutation_p.A3G	NM_007238	NP_009169	Q9Y6I8	PXMP4_HUMAN	peroxisomal membrane protein 4 isoform a	3						integral to membrane|membrane fraction|peroxisomal membrane					0														0.466667	9.254574	9.280302	7	8	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	31771667	31771667	13309	20	G	C	C	42	42	PXMP4	C	3	3
CSTF1	1477	broad.mit.edu	36	20	54407818	54407818	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr20:54407818C>T	uc002xxl.1	+	c.1034C>T	c.(1033-1035)ACG>ATG	p.T345M	CSTF1_uc002xxm.1_Missense_Mutation_p.T345M|CSTF1_uc002xxn.1_Missense_Mutation_p.T345M|CSTF1_uc002xxo.1_Missense_Mutation_p.T288M	NM_001033521	NP_001315	Q05048	CSTF1_HUMAN	cleavage stimulation factor subunit 1	345					mRNA cleavage|mRNA polyadenylation|nuclear mRNA splicing, via spliceosome|termination of RNA polymerase II transcription	nucleoplasm	protein binding|RNA binding			central_nervous_system(1)	1														0.433333	240.028266	240.724663	78	102	CC		KEEP	---	---	---	---	capture	Colorectal(105;0.202)		Missense_Mutation	SNP	54407818	54407818	4124	20	C	T	T	19	19	CSTF1	T	1	1
CXADR	1525	broad.mit.edu	36	21	17855662	17855662	+	Missense_Mutation	SNP	T	C	C			TCGA-26-5134-01	TCGA-26-5134-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr21:17855662T>C	uc002yki.1	+	c.830T>C	c.(829-831)ATC>ACC	p.I277T	CXADR_uc002ykh.1_Intron|CXADR_uc010gld.1_Intron|CXADR_uc010gle.1_Intron|CXADR_uc002ykj.1_Missense_Mutation_p.I250T	NM_001338	NP_001329	P78310	CXAR_HUMAN	coxsackie virus and adenovirus receptor	277	Cytoplasmic (Potential).				blood coagulation|cell adhesion|interspecies interaction between organisms|leukocyte migration|regulation of immune response	adherens junction|basolateral plasma membrane|extracellular region|integral to plasma membrane|nucleus|tight junction	receptor activity			ovary(1)	1														0.422535	106.249727	106.618663	30	41	TT		KEEP	---	---	---	---	capture		Epithelial(23;0.000206)|all cancers(11;0.000302)|OV - Ovarian serous cystadenocarcinoma(11;0.0194)|Lung(58;0.0233)|COAD - Colon adenocarcinoma(22;0.0389)|Colorectal(24;0.0483)|LUSC - Lung squamous cell carcinoma(23;0.0782)	Missense_Mutation	SNP	17855662	17855662	4236	21	T	C	C	50	50	CXADR	C	4	4
ROCK2	9475	broad.mit.edu	36	2	11249752	11249752	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:11249752C>T	uc002rbd.1	-	c.4136G>A	c.(4135-4137)AGT>AAT	p.S1379N		NM_004850	NP_004841	O75116	ROCK2_HUMAN	Rho-associated, coiled-coil containing protein	1379					axon guidance|cytokinesis|intracellular signal transduction|protein phosphorylation	cytosol|plasma membrane	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity|structural molecule activity			skin(2)|stomach(1)	3	all_hematologic(175;0.127)|Acute lymphoblastic leukemia(172;0.155)									587				0.392971	354.146719	357.289015	123	190	CC		KEEP	---	---	---	---	capture		Epithelial(75;0.137)|OV - Ovarian serous cystadenocarcinoma(76;0.162)	Missense_Mutation	SNP	11249752	11249752	13997	2	C	T	T	20	20	ROCK2	T	2	2
WIPF1	7456	broad.mit.edu	36	2	175140893	175140893	+	Silent	SNP	A	C	C	rs34236584	unknown	TCGA-26-5134-01	TCGA-26-5134-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr2:175140893A>C	uc010fqt.1	-	c.1284T>G	c.(1282-1284)CCT>CCG	p.P428P	WIPF1_uc002uja.1_Silent_p.P428P|WIPF1_uc002uiy.1_Silent_p.P428P|WIPF1_uc002uiz.1_Silent_p.P428P|WIPF1_uc002ujb.1_Silent_p.P428P	NM_003387	NP_003378	O43516	WIPF1_HUMAN	WAS/WASL interacting protein family, member 1	428	Pro-rich.				actin polymerization or depolymerization|protein complex assembly	cytoplasmic membrane-bounded vesicle	actin binding|profilin binding			ovary(1)	1														0.44	212.999838	213.550253	77	98	AA		KEEP	---	---	---	---	capture			Silent	SNP	175140893	175140893	17941	2	A	C	C	11	11	WIPF1	C	4	4
ITSN2	50618	broad.mit.edu	36	2	24380205	24380205	+	Missense_Mutation	SNP	G	A	A			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr2:24380205G>A	uc002rfe.1	-	c.821C>T	c.(820-822)TCA>TTA	p.S274L	ITSN2_uc002rff.1_Missense_Mutation_p.S274L|ITSN2_uc002rfg.1_Missense_Mutation_p.S274L|ITSN2_uc010eyd.1_Missense_Mutation_p.S300L	NM_006277	NP_006268	Q9NZM3	ITSN2_HUMAN	intersectin 2 isoform 1	275	EH 2.				endocytosis|regulation of Rho protein signal transduction	cytoplasm	calcium ion binding|Rho guanyl-nucleotide exchange factor activity|SH3/SH2 adaptor activity			kidney(2)|ovary(1)|central_nervous_system(1)	4	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)													0.413223	146.616996	147.415321	50	71	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	24380205	24380205	8231	2	G	A	A	45	45	ITSN2	A	2	2
ZNF638	27332	broad.mit.edu	36	2	71430901	71430901	+	Missense_Mutation	SNP	C	A	A			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:71430901C>A	uc002shx.1	+	c.1309C>A	c.(1309-1311)CAT>AAT	p.H437N	ZNF638_uc010fec.1_Missense_Mutation_p.H543N|ZNF638_uc002shw.2_Missense_Mutation_p.H437N|ZNF638_uc002shy.1_Missense_Mutation_p.H437N|ZNF638_uc002shz.1_Missense_Mutation_p.H437N|ZNF638_uc002sia.1_Missense_Mutation_p.H437N|ZNF638_uc002sib.1_Missense_Mutation_p.H437N	NM_014497	NP_055312	Q14966	ZN638_HUMAN	zinc finger protein 638	437					RNA splicing	cytoplasm|nuclear speck	double-stranded DNA binding|nucleotide binding|RNA binding|zinc ion binding			pancreas(2)|ovary(1)	3														0.42623	306.85236	308.012341	104	140	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	71430901	71430901	18650	2	C	A	A	29	29	ZNF638	A	3	3
ADRA2B	151	broad.mit.edu	36	2	96145564	96145564	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:96145564C>T	uc002svi.1	-	c.52G>A	c.(52-54)GCC>ACC	p.A18T		NM_000682	NP_000673	P18089	ADA2B_HUMAN	alpha-2B-adrenergic receptor	18	Helical; Name=1; (By similarity).				activation of MAPK activity by adrenergic receptor signaling pathway|activation of protein kinase B activity|blood coagulation|cell-cell signaling|epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway|negative regulation of epinephrine secretion|negative regulation of norepinephrine secretion|positive regulation of neuron differentiation	integral to plasma membrane	alpha2-adrenergic receptor activity|epinephrine binding|protein binding			ovary(2)|lung(1)	3					Bethanidine(DB00217)|Brimonidine(DB00484)|Debrisoquin(DB04840)|Ergotamine(DB00696)|Fenoldopam(DB00800)|Guanadrel Sulfate(DB00226)|Guanethidine(DB01170)|Lofexidine(DB04948)|Norepinephrine(DB00368)|Yohimbine(DB01392)									0.5	28.026103	28.026103	10	10	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	96145564	96145564	339	2	C	T	T	26	26	ADRA2B	T	2	2
MECOM	2122	broad.mit.edu	36	3	170293455	170293455	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr3:170293455C>T	uc003ffl.2	-	c.3038G>A	c.(3037-3039)AGG>AAG	p.R1013K	MECOM_uc010hwk.1_Missense_Mutation_p.R876K|MECOM_uc010hwl.1_Missense_Mutation_p.R926K|MECOM_uc003ffi.2_Missense_Mutation_p.R862K|MECOM_uc003ffj.2_Missense_Mutation_p.R927K|MECOM_uc003ffn.2_Missense_Mutation_p.R852K|MECOM_uc010hwm.1_Missense_Mutation_p.R862K|MECOM_uc003ffk.2_Missense_Mutation_p.R843K	NM_005241	NP_005232	Q13465	MDS1_HUMAN	ecotropic viral integration site 1 isoform b	Error:Variant_position_missing_in_Q13465_after_alignment							sequence-specific DNA binding transcription factor activity			lung(3)|skin(2)|ovary(1)|pancreas(1)|central_nervous_system(1)	8										646				0.420732	228.048344	228.947763	69	95	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	170293455	170293455	9811	3	C	T	T	24	24	MECOM	T	2	2
SAMD7	344658	broad.mit.edu	36	3	171138867	171138867	+	Missense_Mutation	SNP	A	G	G			TCGA-26-5134-01	TCGA-26-5134-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr3:171138867A>G	uc003fgd.1	+	c.1220A>G	c.(1219-1221)GAT>GGT	p.D407G	SAMD7_uc003fge.1_Missense_Mutation_p.D407G	NM_182610	NP_872416	Q7Z3H4	SAMD7_HUMAN	sterile alpha motif domain containing 7	407										skin(1)	1	all_cancers(22;1.55e-22)|all_epithelial(15;2.41e-27)|all_lung(20;3.52e-17)|Lung NSC(18;1.44e-16)|Ovarian(172;0.000337)|Breast(254;0.169)													0.425676	218.308288	219.02002	63	85	AA		KEEP	---	---	---	---	capture	Lung(28;2.71e-13)|STAD - Stomach adenocarcinoma(35;0.0106)		Missense_Mutation	SNP	171138867	171138867	14304	3	A	G	G	12	12	SAMD7	G	4	4
KIF15	56992	broad.mit.edu	36	3	44857594	44857594	+	Missense_Mutation	SNP	C	G	G			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr3:44857594C>G	uc003cnx.2	+	c.3445C>G	c.(3445-3447)CAA>GAA	p.Q1149E	KIF15_uc010hiq.1_Missense_Mutation_p.Q1052E|KIF15_uc010hir.1_Missense_Mutation_p.Q197E	NM_020242	NP_064627	Q9NS87	KIF15_HUMAN	kinesin family member 15	1149	Potential.				blood coagulation|cell proliferation|microtubule-based movement|mitosis	centrosome|cytosol|microtubule|plus-end kinesin complex|spindle	ATP binding|DNA binding|microtubule motor activity			ovary(1)	1														0.413462	150.790046	151.473844	43	61	CC		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(193;0.0099)|KIRC - Kidney renal clear cell carcinoma(197;0.0564)|Kidney(197;0.0707)	Missense_Mutation	SNP	44857594	44857594	8588	3	C	G	G	29	29	KIF15	G	3	3
SETD2	29072	broad.mit.edu	36	3	47122489	47122489	+	Splice_Site_SNP	SNP	A	G	G			TCGA-26-5134-01	TCGA-26-5134-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr3:47122489A>G	uc003cqs.1	-	c.3330_splice	c.e4+1	p.E1110_splice		NM_014159	NP_054878			SET domain containing 2						oxidation-reduction process|regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleus	DNA binding|histone-lysine N-methyltransferase activity|oxidoreductase activity|transition metal ion binding			kidney(24)|ovary(5)|skin(1)|central_nervous_system(1)|breast(1)	32		Acute lymphoblastic leukemia(5;0.0169)												0.384342	360.250019	363.539584	108	173	AA		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(193;0.000302)|KIRC - Kidney renal clear cell carcinoma(197;0.00732)|Kidney(197;0.00844)	Splice_Site_SNP	SNP	47122489	47122489	14620	3	A	G	G	14	14	SETD2	G	5	4
UQCRC1	7384	broad.mit.edu	36	3	48616679	48616679	+	Missense_Mutation	SNP	T	C	C			TCGA-26-5134-01	TCGA-26-5134-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr3:48616679T>C	uc003cuc.1	-	c.617A>G	c.(616-618)GAG>GGG	p.E206G	UQCRC1_uc003cua.1_Missense_Mutation_p.E91G|UQCRC1_uc003cub.1_Missense_Mutation_p.E206G|UQCRC1_uc003cud.1_Missense_Mutation_p.E206G	NM_003365	NP_003356	P31930	QCR1_HUMAN	ubiquinol-cytochrome c reductase core protein I	206					aerobic respiration|proteolysis		metalloendopeptidase activity|ubiquinol-cytochrome-c reductase activity|zinc ion binding				0					Atovaquone(DB01117)	NSCLC(81;1112 1427 27031 32409 45529)								0.4	371.918362	374.315362	110	165	TT		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(193;0.000293)|KIRC - Kidney renal clear cell carcinoma(197;0.00551)|Kidney(197;0.00621)	Missense_Mutation	SNP	48616679	48616679	17580	3	T	C	C	54	54	UQCRC1	C	4	4
ADH1A	124	broad.mit.edu	36	4	100424776	100424776	+	Missense_Mutation	SNP	G	T	T			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr4:100424776G>T	uc003hur.1	-	c.370C>A	c.(370-372)CTG>ATG	p.L124M	ADH1A_uc010ilf.1_De_novo_Start_InFrame	NM_000667	NP_000658	P07327	ADH1A_HUMAN	class I alcohol dehydrogenase, alpha subunit	124					ethanol oxidation|xenobiotic metabolic process	cytosol	alcohol dehydrogenase activity, zinc-dependent|protein binding|transcription regulator activity|zinc ion binding			large_intestine(1)|ovary(1)	2					Fomepizole(DB01213)|NADH(DB00157)									0.405941	116.349485	117.132021	41	60	GG		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(123;9.56e-08)	Missense_Mutation	SNP	100424776	100424776	308	4	G	T	T	35	35	ADH1A	T	3	3
PRMT10	90826	broad.mit.edu	36	4	148809224	148809224	+	Missense_Mutation	SNP	C	A	A			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr4:148809224C>A	uc003ilc.1	-	c.869G>T	c.(868-870)TGT>TTT	p.C290F	PRMT10_uc003ild.1_Missense_Mutation_p.C177F	NM_138364	NP_612373	Q6P2P2	ANM10_HUMAN	hypothetical protein LOC90826	290						cytoplasm	binding|protein methyltransferase activity			ovary(1)|central_nervous_system(1)	2														0.368421	103.296753	104.743898	35	60	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	148809224	148809224	12979	4	C	A	A	17	17	PRMT10	A	3	3
FGA	2243	broad.mit.edu	36	4	155727503	155727503	+	Missense_Mutation	SNP	C	G	G			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr4:155727503C>G	uc003iod.1	-	c.528G>C	c.(526-528)AAG>AAC	p.K176N	FGA_uc003ioe.1_Missense_Mutation_p.K176N|FGA_uc003iof.1_Intron	NM_000508	NP_000499	P02671	FIBA_HUMAN	fibrinogen, alpha polypeptide isoform alpha-E	176	By similarity.				platelet activation|platelet degranulation|protein polymerization|response to calcium ion|signal transduction	external side of plasma membrane|fibrinogen complex|platelet alpha granule lumen	eukaryotic cell surface binding|protein binding, bridging|receptor binding			ovary(2)|breast(1)	3	all_hematologic(180;0.215)	Renal(120;0.0458)			Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Sucralfate(DB00364)|Tenecteplase(DB00031)	NSCLC(143;340 1922 20892 22370 48145)								0.421965	249.645801	250.565442	73	100	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	155727503	155727503	6067	4	C	G	G	32	32	FGA	G	3	3
ENAM	10117	broad.mit.edu	36	4	71728576	71728576	+	Missense_Mutation	SNP	C	A	A			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr4:71728576C>A	uc003hfm.1	+	c.2569C>A	c.(2569-2571)CCA>ACA	p.P857T		NM_031889	NP_114095	Q9NRM1	ENAM_HUMAN	enamelin	857					bone mineralization|odontogenesis	proteinaceous extracellular matrix	structural constituent of tooth enamel			ovary(3)	3														0.372093	138.366976	140.22086	48	81	CC		KEEP	---	---	---	---	capture	Lung(101;0.235)		Missense_Mutation	SNP	71728576	71728576	5305	4	C	A	A	22	22	ENAM	A	3	3
PTPN13	5783	broad.mit.edu	36	4	87947907	87947907	+	Missense_Mutation	SNP	G	A	A			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr4:87947907G>A	uc003hpy.1	+	c.6931G>A	c.(6931-6933)GCC>ACC	p.A2311T	PTPN13_uc003hpz.1_Missense_Mutation_p.A2306T|PTPN13_uc003hqa.1_Missense_Mutation_p.A2287T|PTPN13_uc003hqb.1_Missense_Mutation_p.A2115T	NM_080685	NP_542416	Q12923	PTN13_HUMAN	protein tyrosine phosphatase, non-receptor type	2306	Tyrosine-protein phosphatase.					cytoplasm|cytoskeleton|plasma membrane	protein binding|protein binding|protein tyrosine phosphatase activity			ovary(4)|breast(1)|kidney(1)	6		Hepatocellular(203;0.114)|all_hematologic(202;0.21)|Acute lymphoblastic leukemia(40;0.242)												0.378788	293.628097	297.034403	100	164	GG		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(123;0.00082)	Missense_Mutation	SNP	87947907	87947907	13237	4	G	A	A	34	34	PTPN13	A	2	2
PCDHA7	56141	broad.mit.edu	36	5	140196051	140196051	+	Silent	SNP	G	A	A			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr5:140196051G>A	uc003lhq.1	+	c.1899G>A	c.(1897-1899)ACG>ACA	p.T633T	PCDHA1_uc003lha.1_Intron|PCDHA1_uc003lhb.1_Intron|PCDHA2_uc003lhd.1_Intron|PCDHA3_uc003lhf.1_Intron|PCDHA4_uc003lhh.1_Intron|PCDHA4_uc003lhi.1_Intron|PCDHA5_uc003lhk.1_Intron|PCDHA5_uc003lhl.1_Intron|PCDHA6_uc003lho.1_Intron|PCDHA6_uc003lhn.1_Intron|PCDHA7_uc003lhp.1_Silent_p.T633T	NM_018910	NP_061733	Q9UN72	PCDA7_HUMAN	protocadherin alpha 7 isoform 1 precursor	633	Cadherin 6.|Extracellular (Potential).				homophilic cell adhesion|nervous system development	integral to plasma membrane	calcium ion binding|protein binding			ovary(1)	1						NSCLC(160;258 2013 5070 22440 28951)								0.447154	155.17071	155.474175	55	68	GG		KEEP	---	---	---	---	capture	KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)		Silent	SNP	140196051	140196051	11949	5	G	A	A	37	37	PCDHA7	A	1	1
MTHFD1L	25902	broad.mit.edu	36	6	151323106	151323106	+	Silent	SNP	G	A	A			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr6:151323106G>A	uc003qob.1	+	c.1806G>A	c.(1804-1806)GCG>GCA	p.A602A	MTHFD1L_uc003qoc.1_Silent_p.A550A	NM_015440	NP_056255	Q6UB35	C1TM_HUMAN	methylenetetrahydrofolate dehydrogenase (NADP+	602	Formyltetrahydrofolate synthetase.				folic acid-containing compound biosynthetic process|formate metabolic process|one-carbon metabolic process|tetrahydrofolate metabolic process	mitochondrion	ATP binding|formate-tetrahydrofolate ligase activity|protein homodimerization activity			ovary(3)|large_intestine(1)	4		Ovarian(120;0.128)												0.357143	123.150174	125.410396	45	81	GG		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(155;8.7e-12)	Silent	SNP	151323106	151323106	10321	6	G	A	A	38	38	MTHFD1L	A	1	1
HSPA1L	3305	broad.mit.edu	36	6	31886886	31886886	+	Missense_Mutation	SNP	C	A	A			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr6:31886886C>A	uc003nxh.1	-	c.843G>T	c.(841-843)CAG>CAT	p.Q281H	HSPA1L_uc010jte.1_Missense_Mutation_p.Q281H|HSPA1L_uc010jtf.1_Missense_Mutation_p.Q281H	NM_005527	NP_005518	P34931	HS71L_HUMAN	heat shock 70kDa protein 1-like	281					response to unfolded protein		ATP binding			ovary(3)|kidney(1)|pleura(1)	5										2				0.454106	271.697198	272.080142	94	113	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	31886886	31886886	7709	6	C	A	A	24	24	HSPA1L	A	3	3
TNXB	7148	broad.mit.edu	36	6	32172312	32172312	+	Silent	SNP	C	G	G			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr6:32172312C>G	uc003nzl.2	-	c.1296G>C	c.(1294-1296)TCG>TCC	p.S432S		NM_019105	NP_061978	P22105	TENX_HUMAN	tenascin XB isoform 1 precursor	432	EGF-like 10.				actin cytoskeleton organization|cell adhesion|collagen metabolic process|elastic fiber assembly|signal transduction	extracellular space|intracellular|proteinaceous extracellular matrix	heparin binding|integrin binding				0														0.5	11.366949	11.366949	5	5	CC		KEEP	---	---	---	---	capture			Silent	SNP	32172312	32172312	16887	6	C	G	G	27	27	TNXB	G	3	3
PKHD1	5314	broad.mit.edu	36	6	51592104	51592104	+	Missense_Mutation	SNP	G	C	C			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr6:51592104G>C	uc003pah.1	-	c.11959C>G	c.(11959-11961)CCT>GCT	p.P3987A		NM_138694	NP_619639	P08F94	PKHD1_HUMAN	fibrocystin isoform 1	3987	Cytoplasmic (Potential).				cell-cell adhesion|cilium assembly|homeostatic process|kidney development|negative regulation of cellular component movement	anchored to external side of plasma membrane|apical plasma membrane|integral to membrane|microtubule basal body	protein binding|receptor activity			ovary(12)|large_intestine(5)|central_nervous_system(3)	20	Lung NSC(77;0.0605)									1537				0.345972	239.311424	243.731345	73	138	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	51592104	51592104	12396	6	G	C	C	41	41	PKHD1	C	3	3
MOGAT3	346606	broad.mit.edu	36	7	100628320	100628320	+	Silent	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr7:100628320C>T	uc003uyc.1	-	c.540G>A	c.(538-540)CAG>CAA	p.Q180Q	MOGAT3_uc010lhr.1_Silent_p.Q180Q	NM_178176	NP_835470	Q86VF5	MOGT3_HUMAN	monoacylglycerol O-acyltransferase 3	180					glycerol metabolic process|lipid biosynthetic process	endoplasmic reticulum membrane|integral to membrane	2-acylglycerol O-acyltransferase activity|diacylglycerol O-acyltransferase activity			ovary(2)	2	Lung NSC(181;0.168)|all_lung(186;0.215)													0.458333	133.585875	133.730973	44	52	CC		KEEP	---	---	---	---	capture			Silent	SNP	100628320	100628320	10087	7	C	T	T	28	28	MOGAT3	T	2	2
TRIL	9865	broad.mit.edu	36	7	28963436	28963436	+	Missense_Mutation	SNP	T	G	G			TCGA-26-5134-01	TCGA-26-5134-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr7:28963436T>G	uc003szt.1	-	c.752A>C	c.(751-753)CAC>CCC	p.H251P		NM_014817	NP_055632	Q7L0X0	TRIL_HUMAN	hypothetical protein LOC9865	251	Extracellular (Potential).|LRR 8.				inflammatory response|innate immune response|regulation of cytokine production involved in immune response|toll-like receptor 4 signaling pathway	lipopolysaccharide receptor complex	lipopolysaccharide binding				0														0.388889	9.582117	9.818202	7	11	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	28963436	28963436	17029	7	T	G	G	59	59	TRIL	G	4	4
NRBP2	340371	broad.mit.edu	36	8	144990027	144990027	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr8:144990027C>T	uc003yzw.1	-	c.764G>A	c.(763-765)AGC>AAC	p.S255N	NRBP2_uc003yzv.2_Missense_Mutation_p.S220N|NRBP2_uc010mfl.1_Silent_p.Q285Q|NRBP2_uc010mfm.1_Intron|NRBP2_uc003yzx.1_Non-coding_Transcript|NRBP2_uc003yzy.1_Missense_Mutation_p.S220N|NRBP2_uc003yzz.1_Silent_p.Q143Q	NM_178564	NP_848659	Q9NSY0	NRBP2_HUMAN	nuclear receptor binding protein 2	463					negative regulation of neuron apoptosis|neuron differentiation|protein phosphorylation	cytoplasm	ATP binding|protein kinase activity			central_nervous_system(2)	2	all_cancers(97;2.31e-11)|all_epithelial(106;1.58e-09)|Lung NSC(106;0.00013)|all_lung(105;0.000374)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)									69				0.285714	8.791982	9.370538	4	10	CC		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(54;2.46e-41)|Epithelial(56;1.23e-39)|all cancers(56;6.82e-35)|Colorectal(110;0.055)|BRCA - Breast invasive adenocarcinoma(115;0.18)		Missense_Mutation	SNP	144990027	144990027	11048	8	C	T	T	28	28	NRBP2	T	2	2
KCNU1	157855	broad.mit.edu	36	8	36780734	36780734	+	Missense_Mutation	SNP	C	G	G			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr8:36780734C>G	uc010lvw.1	+	c.347C>G	c.(346-348)TCT>TGT	p.S116C	KCNU1_uc003xjw.2_Non-coding_Transcript	NM_001031836	NP_001027006	A8MYU2	KCNU1_HUMAN	potassium channel, subfamily U, member 1	116	Helical; Name=Segment S1; (Potential).					voltage-gated potassium channel complex	binding|catalytic activity|large conductance calcium-activated potassium channel activity|voltage-gated potassium channel activity			ovary(1)	1														0.5	18.675187	18.675187	5	5	CC		KEEP	---	---	---	---	capture		KIRC - Kidney renal clear cell carcinoma(67;0.0504)|Kidney(114;0.0634)	Missense_Mutation	SNP	36780734	36780734	8398	8	C	G	G	32	32	KCNU1	G	3	3
SNX16	64089	broad.mit.edu	36	8	82877182	82877182	+	Missense_Mutation	SNP	T	A	A			TCGA-26-5134-01	TCGA-26-5134-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr8:82877182T>A	uc003ycm.1	-	c.926A>T	c.(925-927)GAT>GTT	p.D309V	SNX16_uc003ycn.1_Missense_Mutation_p.D309V|SNX16_uc003yco.1_Missense_Mutation_p.D280V	NM_022133	NP_690049	P57768	SNX16_HUMAN	sorting nexin 16 isoform a	309				LDEE -> WMR (in Ref. 1; AAG25676).	cell communication|early endosome to late endosome transport|endosome to lysosome transport|protein targeting to lysosome	early endosome membrane|extrinsic to endosome membrane|late endosome membrane|lysosome	identical protein binding|phosphatidylinositol binding			ovary(1)|pancreas(1)	2														0.384615	91.43251	92.342613	30	48	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	82877182	82877182	15387	8	T	A	A	50	50	SNX16	A	4	4
FUT7	2529	broad.mit.edu	36	9	139045459	139045459	+	Missense_Mutation	SNP	G	C	C			TCGA-26-5134-01	TCGA-26-5134-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr9:139045459G>C	uc004ckq.2	-	c.553C>G	c.(553-555)CTG>GTG	p.L185V	ABCA2_uc010nby.1_5'Flank|ABCA2_uc010nbz.1_5'Flank|ABCA2_uc004ckl.1_5'Flank|ABCA2_uc004ckm.1_5'Flank|C9orf139_uc004ckp.1_Intron	NM_004479	NP_004470	Q11130	FUT7_HUMAN	fucosyltransferase 7	185	Lumenal (Potential).				L-fucose catabolic process|protein glycosylation	Golgi cisterna membrane|integral to membrane	alpha(1,3)-fucosyltransferase activity				0	all_cancers(76;0.0893)	Myeloproliferative disorder(178;0.0511)												0.236842	13.519465	15.964865	9	29	GG		KEEP	---	---	---	---	capture	STAD - Stomach adenocarcinoma(284;0.123)	OV - Ovarian serous cystadenocarcinoma(145;2.96e-05)|Epithelial(140;0.000486)	Missense_Mutation	SNP	139045459	139045459	6360	9	G	C	C	34	34	FUT7	C	3	3
TAF1L	138474	broad.mit.edu	36	9	32625178	32625178	+	Missense_Mutation	SNP	A	G	G			TCGA-26-5134-01	TCGA-26-5134-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr9:32625178A>G	uc003zrg.1	-	c.400T>C	c.(400-402)TAC>CAC	p.Y134H		NM_153809	NP_722516	Q8IZX4	TAF1L_HUMAN	TBP-associated factor RNA polymerase 1-like	134					male meiosis|regulation of transcription from RNA polymerase II promoter|transcription initiation, DNA-dependent	transcription factor TFIID complex	DNA binding|histone acetyltransferase activity|protein serine/threonine kinase activity|TBP-class protein binding|transcription activator activity			lung(8)|large_intestine(3)|central_nervous_system(3)|skin(2)|ovary(2)|breast(1)|pancreas(1)	20										234				0.359307	277.373371	281.39383	83	148	AA		KEEP	---	---	---	---	capture	LUSC - Lung squamous cell carcinoma(29;0.0181)	GBM - Glioblastoma multiforme(74;0.00301)	Missense_Mutation	SNP	32625178	32625178	16044	9	A	G	G	13	13	TAF1L	G	4	4
PIGO	84720	broad.mit.edu	36	9	35080223	35080223	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr9:35080223C>T	uc003zwd.1	-	c.2909G>A	c.(2908-2910)CGG>CAG	p.R970Q	PIGO_uc003zwc.1_3'UTR|PIGO_uc003zwe.1_Missense_Mutation_p.R553Q|PIGO_uc003zwf.1_Missense_Mutation_p.R553Q|PIGO_uc003zwg.1_3'UTR	NM_032634	NP_116023	Q8TEQ8	PIGO_HUMAN	phosphatidylinositol glycan anchor biosynthesis,	970					C-terminal protein lipidation|preassembly of GPI anchor in ER membrane	endoplasmic reticulum membrane|integral to membrane	transferase activity			large_intestine(1)|ovary(1)|skin(1)	3														0.370079	136.089464	137.973964	47	80	CC		KEEP	---	---	---	---	capture	LUSC - Lung squamous cell carcinoma(32;0.00343)|Lung(28;0.00778)		Missense_Mutation	SNP	35080223	35080223	12318	9	C	T	T	23	23	PIGO	T	1	1
RGAG1	57529	broad.mit.edu	36	X	109582346	109582346	+	Silent	SNP	C	A	A			TCGA-26-5134-01	TCGA-26-5134-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chrX:109582346C>A	uc004eor.1	+	c.1845C>A	c.(1843-1845)TCC>TCA	p.S615S		NM_020769	NP_065820	Q8NET4	RGAG1_HUMAN	retrotransposon gag domain containing 1	615										lung(2)|ovary(1)	3														0.157895	10.51903	16.918085	9	48	CC		KEEP	---	---	---	---	capture			Silent	SNP	109582346	109582346	13747	23	C	A	A	21	21	RGAG1	A	3	3
IRS2	8660	broad.mit.edu	36	13	109232968	109232969	+	Frame_Shift_Ins	INS	-	G	G			TCGA-26-5134-01	TCGA-26-5134-01										Phase_I	Unspecified				Illumina GAIIx	g.chr13:109232968_109232969insG	uc001vqv.1	-	c.3433_3434insC	c.(3433-3435)CGCfs	p.R1145fs		NM_003749	NP_003740	Q9Y4H2	IRS2_HUMAN	insulin receptor substrate 2	1145					fibroblast growth factor receptor signaling pathway|glucose metabolic process|insulin receptor signaling pathway|lipid homeostasis|negative regulation of B cell apoptosis|negative regulation of kinase activity|negative regulation of plasma membrane long-chain fatty acid transport|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of B cell proliferation|positive regulation of fatty acid beta-oxidation|positive regulation of glucose import|positive regulation of glycogen biosynthetic process|positive regulation of insulin secretion|response to glucose stimulus	cytosol|plasma membrane	insulin receptor binding|signal transducer activity			large_intestine(2)|upper_aerodigestive_tract(1)|kidney(1)|skin(1)	5	all_cancers(4;7.57e-15)|all_epithelial(4;5.91e-09)|all_lung(23;7.64e-07)|Lung NSC(43;0.000183)|Colorectal(4;0.00159)|all_neural(89;0.00294)|Medulloblastoma(90;0.00596)|Lung SC(71;0.0155)	Breast(118;0.159)	all cancers(43;0.00815)|BRCA - Breast invasive adenocarcinoma(86;0.11)|Epithelial(84;0.127)|GBM - Glioblastoma multiforme(44;0.147)			Melanoma(100;613 2409 40847)				156				0.38			3	5				---	---	---	---	capture_indel			Frame_Shift_Ins	INS	109232968	109232969	8145	13	-	G	G	27	27	IRS2	G	5	5
FAM113A	64773	broad.mit.edu	36	20	2767125	2767125	+	Splice_Site_Del	DEL	C	-	-			TCGA-26-5134-01	TCGA-26-5134-01										Phase_I	Unspecified				Illumina GAIIx	g.chr20:2767125_2767125delC	uc002wgz.1	-	c.e6_splice_site			FAM113A_uc002wha.1_Intron|FAM113A_uc002whb.1_Intron|FAM113A_uc002whc.1_Splice_Site_Del|VPS16_uc002whe.1_5'Flank|VPS16_uc002whf.1_5'Flank|VPS16_uc002whd.1_5'Flank	NM_022760	NP_073597			hypothetical protein LOC64773								hydrolase activity|protein binding			ovary(2)	2														0.45			57	69				---	---	---	---	capture_indel			Splice_Site_Del	DEL	2767125	2767125	5598	20	C	-	-	28	28	FAM113A	-	5	5
PDGFRA	5156	broad.mit.edu	36	4	54828645	54828656	+	In_Frame_Del	DEL	GGAAAAGATTCA	-	-			TCGA-26-5134-01	TCGA-26-5134-01										Phase_I	Unspecified				Illumina GAIIx	g.chr4:54828645_54828656delGGAAAAGATTCA	uc003han.2	+	c.1101_1112delGGAAAAGATTCA	c.(1099-1113)GTGGAAAAGATTCAG>GTG	p.EKIQ368del	PDGFRA_uc003haa.1_Intron|PDGFRA_uc010igq.1_In_Frame_Del_p.EKIQ262del|PDGFRA_uc003ham.2_Non-coding_Transcript	NM_006206	NP_006197	P16234	PGFRA_HUMAN	platelet-derived growth factor receptor alpha	368_371	Ig-like C2-type 4.|Extracellular (Potential).				cardiac myofibril assembly|cell activation|luteinization|metanephric glomerular capillary formation|peptidyl-tyrosine phosphorylation|positive regulation of cell migration|positive regulation of DNA replication|positive regulation of fibroblast proliferation|protein autophosphorylation|retina vasculature development in camera-type eye	cytoplasm|integral to plasma membrane|nucleus	ATP binding|platelet-derived growth factor alpha-receptor activity|platelet-derived growth factor binding|platelet-derived growth factor receptor binding|protein homodimerization activity|vascular endothelial growth factor receptor activity			soft_tissue(532)|small_intestine(40)|stomach(16)|central_nervous_system(13)|lung(9)|haematopoietic_and_lymphoid_tissue(7)|ovary(3)|skin(2)|gastrointestinal_tract_(site_indeterminate)(1)|autonomic_ganglia(1)|bone(1)	625	all_cancers(7;0.000425)|all_lung(4;0.000343)|Lung NSC(11;0.000467)|all_epithelial(27;0.0131)|all_neural(26;0.0209)|Glioma(25;0.08)		GBM - Glioblastoma multiforme(1;4.18e-71)|all cancers(1;4.76e-45)|LUSC - Lung squamous cell carcinoma(32;0.00256)		Becaplermin(DB00102)|Imatinib(DB00619)|Sunitinib(DB01268)	Pancreas(151;208 1913 7310 23853 37092)				1045	TSP Lung(21;0.16)			0.52			278	261				---	---	---	---	capture_indel			In_Frame_Del	DEL	54828645	54828656	12082	4	GGAAAAGATTCA	-	-	47	47	PDGFRA	-	5	5
SSPO	23145	broad.mit.edu	36	7	149134850	149134853	+	Splice_Site_Del	DEL	GATA	-	-			TCGA-26-5134-01	TCGA-26-5134-01										Phase_I	Unspecified				Illumina GAIIx	g.chr7:149134850_149134853delGATA	uc010lpk.1	+	c.e60_splice_site				NM_198455	NP_940857			SCO-spondin						cell adhesion	extracellular space	peptidase inhibitor activity				0	Melanoma(164;0.165)|Ovarian(565;0.177)		OV - Ovarian serous cystadenocarcinoma(82;0.00625)											0.36			4	7				---	---	---	---	capture_indel			Splice_Site_Del	DEL	149134850	149134853	15705	7	GATA	-	-	41	41	SSPO	-	5	5
