Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Genome_Change	Annotation_Transcript	Transcript_Strand	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	i_TCGAscape_Amplification_Peaks	i_TCGAscape_Deletion_Peaks	DrugBank	i_ACHILLES_Top_Genes	i_CCLE_ONCOMAP_overlapping_mutations	i_CCLE_ONCOMAP_total_mutations_in_gene	i_CCLE_SEQ_overlapping_mutations	i_CCLE_SEQ_total_mutations_in_gene	MUTSIG_Significant_Genes	OREGANNO_ID	OREGANNO_Values	i_tumor_f	i_init_t_lod	i_t_lod_fstar	i_t_alt_count	i_t_ref_count	i_normal_best_gt	i_failure_reasons	i_judgement	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	dataset	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	type	classification	start	end	gene	chr	ref_allele	tum_allele1	tum_allele2	context_orig	context65	gene_name	newbase	categ	categ_ignoring_null_categ
LBX1	10660	broad.mit.edu	36	10	102977479	102977479	+	Silent	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr10:102977479C>T	uc001ksx.1	-	c.384G>A	c.(382-384)TCG>TCA	p.S128S		NM_006562	NP_006553	P52954	LBX1_HUMAN	ladybird homeobox 1	128	Homeobox.				muscle organ development		sequence-specific DNA binding|transcription regulator activity				0		Colorectal(252;0.234)												0.888889	177.132651	186.56275	56	7	CC		KEEP	---	---	---	---	capture		Epithelial(162;3.22e-09)|all cancers(201;1.79e-07)	Silent	SNP	102977479	102977479	8976	10	C	T	T	27	27	LBX1	T	1	1
CELF2	10659	broad.mit.edu	36	10	11403341	11403341	+	Missense_Mutation	SNP	G	C	C			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr10:11403341G>C	uc001ikk.2	+	c.1316G>C	c.(1315-1317)GGC>GCC	p.G439A	CELF2_uc001iki.2_Missense_Mutation_p.G414A|CELF2_uc001ikl.2_Missense_Mutation_p.G427A|CELF2_uc001iko.2_Missense_Mutation_p.G394A|CELF2_uc001ikp.2_Missense_Mutation_p.G396A	NM_001083591	NP_001077060	O95319	CELF2_HUMAN	CUG triplet repeat, RNA binding protein 2	414	Necessary for RNA-binding, TNNT2 exon 5 and NMDA R1 exon 21 inclusion.				mRNA processing|regulation of heart contraction	cytoplasm|nucleus	nucleotide binding|protein binding|RNA binding				0														0.444444	7.350845	7.381112	4	5	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	11403341	11403341	3349	10	G	C	C	42	42	CELF2	C	3	3
DGKZ	8525	broad.mit.edu	36	11	46349625	46349625	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr11:46349625G>A	uc001ncn.1	+	c.1219G>A	c.(1219-1221)GTG>ATG	p.V407M	DGKZ_uc001nch.1_Missense_Mutation_p.V235M|DGKZ_uc001ncj.1_Missense_Mutation_p.V185M|DGKZ_uc001nck.1_De_novo_Start_InFrame|DGKZ_uc001ncl.2_Missense_Mutation_p.V219M|DGKZ_uc001ncm.2_Missense_Mutation_p.V218M|DGKZ_uc009yky.1_Missense_Mutation_p.V219M	NM_001105540	NP_001099010	Q13574	DGKZ_HUMAN	diacylglycerol kinase zeta isoform 4	407	Phorbol-ester/DAG-type 2.				activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|cell migration|intracellular signal transduction|mitotic cell cycle G1/S transition DNA damage checkpoint|negative regulation of mitotic cell cycle|platelet activation	cytoplasm|lamellipodium|nucleus|plasma membrane	ATP binding|diacylglycerol kinase activity|diacylglycerol kinase activity|lipid kinase activity|metal ion binding|protein binding|protein C-terminus binding			pancreas(1)|central_nervous_system(1)|skin(1)	3														0.373134	68.15829	69.10512	25	42	GG		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(35;0.0259)|Lung(87;0.141)	Missense_Mutation	SNP	46349625	46349625	4653	11	G	A	A	44	44	DGKZ	A	2	2
OR52B2	255725	broad.mit.edu	36	11	6147210	6147210	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr11:6147210C>T	uc001mch.1	-	c.923G>A	c.(922-924)CGG>CAG	p.R308Q		NM_001004052	NP_001004052	Q96RD2	O52B2_HUMAN	olfactory receptor, family 52, subfamily B,	308	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity				0		Medulloblastoma(188;0.00776)|all_neural(188;0.0652)|Breast(177;0.114)				NSCLC(5;186 261 1778 7098 14207)								0.393939	114.80995	115.78254	39	60	CC		KEEP	---	---	---	---	capture		Epithelial(150;3.69e-08)|BRCA - Breast invasive adenocarcinoma(625;0.135)	Missense_Mutation	SNP	6147210	6147210	11521	11	C	T	T	23	23	OR52B2	T	1	1
CRY1	1407	broad.mit.edu	36	12	105917682	105917682	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr12:105917682C>T	uc001tmi.2	-	c.914G>A	c.(913-915)CGC>CAC	p.R305H		NM_004075	NP_004066	Q16526	CRY1_HUMAN	cryptochrome 1 (photolyase-like)	305	FAD-binding.				circadian rhythm|DNA repair|protein-chromophore linkage|regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrion|nucleus	DNA binding|DNA photolyase activity|G-protein coupled photoreceptor activity|nucleotide binding|protein binding			ovary(3)	3														0.434211	93.059564	93.346921	33	43	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	105917682	105917682	4042	12	C	T	T	27	27	CRY1	T	1	1
ATF7	11016	broad.mit.edu	36	12	52211806	52211806	+	Missense_Mutation	SNP	C	G	G			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr12:52211806C>G	uc001sdy.1	-	c.949G>C	c.(949-951)GCC>CCC	p.A317P	ATF7_uc001sdz.1_Missense_Mutation_p.A306P	NM_006856	NP_006847	P17544	ATF7_HUMAN	activating transcription factor 7 isoform 2	317					interspecies interaction between organisms|regulation of transcription, DNA-dependent	cytoplasm|nuclear periphery|nucleoplasm	protein dimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(1)	1														0.235294	7.003378	8.088486	4	13	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	52211806	52211806	1105	12	C	G	G	25	25	ATF7	G	3	3
TRHDE	29953	broad.mit.edu	36	12	71343168	71343168	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:71343168G>A	uc001sxa.1	+	c.3001G>A	c.(3001-3003)GAA>AAA	p.E1001K		NM_013381	NP_037513	Q9UKU6	TRHDE_HUMAN	thyrotropin-releasing hormone degrading enzyme	1001	Extracellular (Potential).				cell-cell signaling|proteolysis|signal transduction	integral to plasma membrane	aminopeptidase activity|metallopeptidase activity|zinc ion binding			ovary(2)	2														0.496183	195.278726	195.280253	65	66	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	71343168	71343168	17023	12	G	A	A	37	37	TRHDE	A	1	1
PEX5	5830	broad.mit.edu	36	12	7234779	7234779	+	Missense_Mutation	SNP	A	G	G			TCGA-27-2523-01	TCGA-27-2523-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr12:7234779A>G	uc009zfu.1	+	c.176A>G	c.(175-177)GAA>GGA	p.E59G	PEX5_uc001qsu.1_Missense_Mutation_p.E59G|PEX5_uc009zfv.1_Missense_Mutation_p.E59G|PEX5_uc001qsv.1_Missense_Mutation_p.E59G|PEX5_uc001qsw.1_Missense_Mutation_p.E59G	NM_000319	NP_000310	P50542	PEX5_HUMAN	peroxisomal biogenesis factor 5 isoform b	59					protein import into peroxisome matrix, translocation|protein targeting to peroxisome|protein tetramerization|protein transport	cytosol|peroxisomal matrix|peroxisomal membrane	peroxisome matrix targeting signal-1 binding|protein C-terminus binding|protein N-terminus binding			ovary(1)	1														0.438776	294.536898	295.174726	86	110	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	7234779	7234779	12170	12	A	G	G	9	9	PEX5	G	4	4
NAP1L1	4673	broad.mit.edu	36	12	74733848	74733848	+	Missense_Mutation	SNP	A	C	C			TCGA-27-2523-01	TCGA-27-2523-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr12:74733848A>C	uc001sxw.1	-	c.739T>G	c.(739-741)TTT>GTT	p.F247V	NAP1L1_uc001sxv.1_Missense_Mutation_p.F205V|NAP1L1_uc001sxx.1_Missense_Mutation_p.F247V|NAP1L1_uc001sxy.1_Missense_Mutation_p.F184V|NAP1L1_uc001sxz.1_Missense_Mutation_p.F178V|NAP1L1_uc001syc.1_Missense_Mutation_p.F258V|NAP1L1_uc001syb.1_Missense_Mutation_p.F247V|NAP1L1_uc001sya.1_Missense_Mutation_p.F205V	NM_004537	NP_631946	P55209	NP1L1_HUMAN	nucleosome assembly protein 1-like 1	247					DNA replication|nucleosome assembly|positive regulation of cell proliferation	chromatin assembly complex|melanosome	protein binding			ovary(1)	1		Colorectal(145;0.09)												0.450382	202.0147	202.294941	59	72	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	74733848	74733848	10552	12	A	C	C	1	1	NAP1L1	C	4	4
CD163	9332	broad.mit.edu	36	12	7542937	7542937	+	Missense_Mutation	SNP	T	A	A			TCGA-27-2523-01	TCGA-27-2523-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr12:7542937T>A	uc001qsz.2	-	c.572A>T	c.(571-573)GAT>GTT	p.D191V	CD163_uc001qta.2_Missense_Mutation_p.D191V|CD163_uc009zfw.1_Missense_Mutation_p.D191V	NM_004244	NP_004235	Q86VB7	C163A_HUMAN	CD163 antigen isoform a	191	SRCR 2.|Extracellular (Potential).				acute-phase response	extracellular region|integral to plasma membrane	protein binding|scavenger receptor activity			ovary(6)|pancreas(1)|skin(1)	8														0.408922	659.867201	663.771981	220	318	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	7542937	7542937	3094	12	T	A	A	50	50	CD163	A	4	4
PCDH9	5101	broad.mit.edu	36	13	66700036	66700036	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr13:66700036C>T	uc001vik.1	-	c.538G>A	c.(538-540)GAA>AAA	p.E180K	PCDH9_uc001vil.1_Missense_Mutation_p.E180K|PCDH9_uc001vin.2_Missense_Mutation_p.E180K	NM_203487	NP_982354	Q9HC56	PCDH9_HUMAN	protocadherin 9 isoform 1 precursor	180	Extracellular (Potential).|Cadherin 2.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(4)|pancreas(1)	5		Hepatocellular(98;0.0906)|Breast(118;0.107)												0.390879	328.712784	331.919173	120	187	CC		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(99;0.00819)	Missense_Mutation	SNP	66700036	66700036	11938	13	C	T	T	29	29	PCDH9	T	2	2
OR11H4	390442	broad.mit.edu	36	14	19781762	19781762	+	Silent	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr14:19781762G>A	uc001vws.1	+	c.972G>A	c.(970-972)TCG>TCA	p.S324S		NM_001004479	NP_001004479	Q8NGC9	O11H4_HUMAN	olfactory receptor, family 11, subfamily H,	324	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)	1	all_cancers(95;0.000888)													0.380282	151.305865	153.094074	54	88	GG		KEEP	---	---	---	---	capture	Epithelial(56;1.75e-06)|all cancers(55;1.22e-05)	GBM - Glioblastoma multiforme(265;0.0146)	Silent	SNP	19781762	19781762	11334	14	G	A	A	40	40	OR11H4	A	1	1
ITGA11	22801	broad.mit.edu	36	15	66399739	66399739	+	Silent	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr15:66399739G>A	uc010bib.1	-	c.2454C>T	c.(2452-2454)TCC>TCT	p.S818S	ITGA11_uc002ari.1_Silent_p.S818S	NM_001004439	NP_001004439	Q9UKX5	ITA11_HUMAN	integrin, alpha 11 precursor	818	Extracellular (Potential).				cell-matrix adhesion|integrin-mediated signaling pathway|muscle organ development	integrin complex	collagen binding|receptor activity			kidney(2)|pancreas(1)	3					Tirofiban(DB00775)									0.636364	23.527752	23.707619	7	4	GG		KEEP	---	---	---	---	capture			Silent	SNP	66399739	66399739	8178	15	G	A	A	39	39	ITGA11	A	1	1
SETD1A	9739	broad.mit.edu	36	16	30883887	30883887	+	Silent	SNP	T	C	C			TCGA-27-2523-01	TCGA-27-2523-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr16:30883887T>C	uc002ead.1	+	c.1323T>C	c.(1321-1323)GGT>GGC	p.G441G		NM_014712	NP_055527	O15047	SET1A_HUMAN	SET domain containing 1A	441	Pro-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nuclear speck|Set1C/COMPASS complex	histone-lysine N-methyltransferase activity|nucleotide binding|protein binding|RNA binding			ovary(2)	2														0.426471	80.76392	81.083878	29	39	TT		KEEP	---	---	---	---	capture			Silent	SNP	30883887	30883887	14618	16	T	C	C	59	59	SETD1A	C	4	4
PRSS36	146547	broad.mit.edu	36	16	31067358	31067358	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr16:31067358C>T	uc002ebd.1	-	c.412G>A	c.(412-414)GCC>ACC	p.A138T		NM_173502	NP_775773	Q5K4E3	POLS2_HUMAN	protease, serine, 36	138	Peptidase S1 1.				proteolysis	cytoplasm|proteinaceous extracellular matrix	serine-type endopeptidase activity			ovary(1)	1														0.4	15.15621	15.284043	6	9	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	31067358	31067358	13075	16	C	T	T	27	27	PRSS36	T	1	1
ABCC11	85320	broad.mit.edu	36	16	46758980	46758980	+	Silent	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr16:46758980G>A	uc002eff.1	-	c.3984C>T	c.(3982-3984)ACC>ACT	p.T1328T	ABCC11_uc002efg.1_Silent_p.T1328T|ABCC11_uc002efh.1_Silent_p.T1290T|ABCC11_uc010cbg.1_Non-coding_Transcript	NM_033151	NP_149163	Q96J66	ABCCB_HUMAN	ATP-binding cassette, sub-family C, member 11	1328	ABC transporter 2.|Cytoplasmic (Potential).					integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of substances			ovary(3)|central_nervous_system(1)	4		all_cancers(37;0.127)|all_lung(18;0.132)|Breast(268;0.166)												0.481203	194.530758	194.56877	64	69	GG		KEEP	---	---	---	---	capture			Silent	SNP	46758980	46758980	52	16	G	A	A	39	39	ABCC11	A	1	1
FOXF1	2294	broad.mit.edu	36	16	85102626	85102626	+	Missense_Mutation	SNP	A	C	C			TCGA-27-2523-01	TCGA-27-2523-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr16:85102626A>C	uc002fjl.1	+	c.950A>C	c.(949-951)AAC>ACC	p.N317T		NM_001451	NP_001442	Q12946	FOXF1_HUMAN	forkhead box F1	317					negative regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of sequence-specific DNA binding transcription factor activity	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding				0														0.3	6.918529	7.277609	3	7	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	85102626	85102626	6250	16	A	C	C	2	2	FOXF1	C	4	4
TUBG1	7283	broad.mit.edu	36	17	38020070	38020070	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr17:38020070C>T	uc002ian.1	+	c.1027C>T	c.(1027-1029)CGC>TGC	p.R343C		NM_001070	NP_001061	P23258	TBG1_HUMAN	tubulin, gamma 1	343					G2/M transition of mitotic cell cycle|meiotic spindle organization|protein polymerization	condensed nuclear chromosome|cytosol|gamma-tubulin complex|polar microtubule	GTP binding|GTPase activity|protein binding|structural constituent of cytoskeleton			ovary(1)	1		Breast(137;0.00116)				Colon(20;114 698 11420 22864)								0.5	129.795944	129.795944	44	44	CC		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(366;0.129)	Missense_Mutation	SNP	38020070	38020070	17319	17	C	T	T	19	19	TUBG1	T	1	1
TNFRSF11A	8792	broad.mit.edu	36	18	58172746	58172746	+	Silent	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr18:58172746G>A	uc002lin.1	+	c.426G>A	c.(424-426)CCG>CCA	p.P142P	TNFRSF11A_uc010dpv.1_Silent_p.P142P	NM_003839	NP_003830	Q9Y6Q6	TNR11_HUMAN	tumor necrosis factor receptor superfamily,	142	Extracellular (Potential).|TNFR-Cys 3.				adaptive immune response|cell-cell signaling|circadian temperature homeostasis|monocyte chemotaxis|osteoclast differentiation|positive regulation of cell proliferation|positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling|positive regulation of fever generation by positive regulation of prostaglandin secretion|positive regulation of JUN kinase activity|positive regulation of NF-kappaB transcription factor activity|response to interleukin-1|response to lipopolysaccharide	external side of plasma membrane|integral to membrane	metal ion binding|tumor necrosis factor receptor activity				0		Colorectal(73;0.188)												0.405063	90.487742	91.108646	32	47	GG		KEEP	---	---	---	---	capture			Silent	SNP	58172746	58172746	16825	18	G	A	A	40	40	TNFRSF11A	A	1	1
LPPR2	64748	broad.mit.edu	36	19	11333001	11333001	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr19:11333001C>T	uc002mre.1	+	c.500C>T	c.(499-501)ACG>ATG	p.T167M	LPPR2_uc002mrf.1_Missense_Mutation_p.T142M|LPPR2_uc010dxy.1_De_novo_Start_OutOfFrame	NM_022737	NP_073574	Q96GM1	LPPR2_HUMAN	lipid phosphate phosphatase-related protein type	167						integral to membrane	phosphatidate phosphatase activity			large_intestine(1)	1						Esophageal Squamous(164;1817 2610 12941 25548)								0.131579	13.216961	28.343865	15	99	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	11333001	11333001	9298	19	C	T	T	19	19	LPPR2	T	1	1
CYP4F8	11283	broad.mit.edu	36	19	15587591	15587591	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:15587591G>A	uc002nbi.1	+	c.164G>A	c.(163-165)CGG>CAG	p.R55Q		NM_007253	NP_009184	P98187	CP4F8_HUMAN	cytochrome P450, family 4, subfamily F,	55					oxidation-reduction process|prostaglandin metabolic process|xenobiotic metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	alkane 1-monooxygenase activity|aromatase activity|electron carrier activity|heme binding|oxygen binding|protein binding			large_intestine(1)	1														0.483146	133.417924	133.43984	43	46	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	15587591	15587591	4356	19	G	A	A	39	39	CYP4F8	A	1	1
KIRREL2	84063	broad.mit.edu	36	19	41043683	41043683	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:41043683G>A	uc002ocb.2	+	c.961G>A	c.(961-963)GTG>ATG	p.V321M	KIRREL2_uc002obz.2_Missense_Mutation_p.V321M|KIRREL2_uc002oca.2_Missense_Mutation_p.V271M|KIRREL2_uc002occ.2_Missense_Mutation_p.V268M|KIRREL2_uc002ocd.2_Missense_Mutation_p.V318M	NM_199180	NP_954649	Q6UWL6	KIRR2_HUMAN	kin of IRRE-like 2 isoform c	321	Extracellular (Potential).|Ig-like C2-type 4.				cell adhesion	integral to membrane|plasma membrane				ovary(1)|central_nervous_system(1)	2	all_lung(56;7.14e-07)|Lung NSC(56;1.12e-06)|Esophageal squamous(110;0.162)													0.238806	36.193071	40.349649	16	51	GG		KEEP	---	---	---	---	capture	LUSC - Lung squamous cell carcinoma(66;0.0515)		Missense_Mutation	SNP	41043683	41043683	8637	19	G	A	A	40	40	KIRREL2	A	1	1
SLC17A7	57030	broad.mit.edu	36	19	54626181	54626181	+	Missense_Mutation	SNP	G	A	A	rs17855709	by-hapmap	TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:54626181G>A	uc002pnp.1	-	c.1292C>T	c.(1291-1293)CCG>CTG	p.P431L	SLC17A7_uc002pno.1_Missense_Mutation_p.P93L	NM_020309	NP_064705	Q9P2U7	VGLU1_HUMAN	solute carrier family 17, member 7	431	Cytoplasmic (Potential).				glutamate secretion|neurotransmitter secretion	cell junction|clathrin sculpted glutamate transport vesicle membrane|integral to membrane|synaptic vesicle membrane|synaptosome	L-glutamate transmembrane transporter activity|sodium-dependent phosphate transmembrane transporter activity|sodium:inorganic phosphate symporter activity			ovary(1)|pancreas(1)	2		all_lung(116;1.62e-07)|Lung NSC(112;8.47e-07)|all_neural(266;0.0381)|Ovarian(192;0.0392)												0.923077	126.927856	133.976604	36	3	GG		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(262;0.00153)|GBM - Glioblastoma multiforme(486;0.0245)	Missense_Mutation	SNP	54626181	54626181	14918	19	G	A	A	39	39	SLC17A7	A	1	1
MUC16	94025	broad.mit.edu	36	19	8823003	8823003	+	Silent	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:8823003G>A	uc002mkp.1	-	c.43374C>T	c.(43372-43374)ATC>ATT	p.I14458I	MUC16_uc010dwh.1_Non-coding_Transcript|MUC16_uc010dwi.1_Non-coding_Transcript|MUC16_uc010dwj.1_Silent_p.I1258I	NM_024690	NP_078966	Q8WXI7	MUC16_HUMAN	mucin 16	13929	Extracellular (Potential).			Missing (in Ref. 3; AAK74120).	cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			ovary(15)|large_intestine(1)|pancreas(1)|breast(1)|skin(1)	19														0.256198	76.667053	83.190222	31	90	GG		KEEP	---	---	---	---	capture			Silent	SNP	8823003	8823003	10367	19	G	A	A	37	37	MUC16	A	1	1
PRMT6	55170	broad.mit.edu	36	1	107401838	107401838	+	Missense_Mutation	SNP	C	G	G			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:107401838C>G	uc001dvb.1	+	c.801C>G	c.(799-801)AAC>AAG	p.N267K		NM_018137	NP_060607	Q96LA8	ANM6_HUMAN	protein arginine methyltransferase 6	326					base-excision repair|interspecies interaction between organisms|negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	histone binding|histone methyltransferase activity (H2A-R3 specific)|histone methyltransferase activity (H3-R2 specific)|histone methyltransferase activity (H4-R3 specific)|protein-arginine omega-N asymmetric methyltransferase activity|protein-arginine omega-N monomethyltransferase activity				0		all_epithelial(167;0.000429)|all_lung(203;0.00122)|Lung NSC(277;0.00185)												0.15625	8.162378	11.768317	5	27	CC		KEEP	---	---	---	---	capture		Lung(183;0.0305)|Epithelial(280;0.0765)|Colorectal(144;0.0998)|all cancers(265;0.14)|LUSC - Lung squamous cell carcinoma(189;0.173)|BRCA - Breast invasive adenocarcinoma(282;0.242)	Missense_Mutation	SNP	107401838	107401838	12983	1	C	G	G	19	19	PRMT6	G	3	3
FCER1A	2205	broad.mit.edu	36	1	157542470	157542470	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:157542470G>A	uc001ftq.1	+	c.400G>A	c.(400-402)GGT>AGT	p.G134S		NM_002001	NP_001992	P12319	FCERA_HUMAN	Fc fragment of IgE, high affinity I, receptor	134	Ig-like 2.|Extracellular (Potential).					integral to plasma membrane					0	all_hematologic(112;0.0429)				Benzylpenicilloyl Polylysine(DB00895)|Omalizumab(DB00043)									0.430894	149.051953	149.564396	53	70	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	157542470	157542470	6011	1	G	A	A	47	47	FCER1A	A	2	2
DUSP27	92235	broad.mit.edu	36	1	165364109	165364109	+	Silent	SNP	C	A	A			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:165364109C>A	uc001geb.1	+	c.3117C>A	c.(3115-3117)CCC>CCA	p.P1039P		NM_001080426	NP_001073895	Q5VZP5	DUS27_HUMAN	dual specificity phosphatase 27 (putative)	1039					protein dephosphorylation		protein tyrosine/serine/threonine phosphatase activity			ovary(3)	3														0.357143	77.382424	78.910427	30	54	CC		KEEP	---	---	---	---	capture			Silent	SNP	165364109	165364109	5009	1	C	A	A	24	24	DUSP27	A	3	3
HMCN1	83872	broad.mit.edu	36	1	184145256	184145256	+	Missense_Mutation	SNP	T	A	A			TCGA-27-2523-01	TCGA-27-2523-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr1:184145256T>A	uc001grq.1	+	c.786T>A	c.(784-786)AAT>AAA	p.N262K		NM_031935	NP_114141	Q96RW7	HMCN1_HUMAN	hemicentin 1	262					bioluminescence|protein-chromophore linkage|response to stimulus|visual perception	basement membrane	calcium ion binding			ovary(22)	22														0.428571	118.930223	119.366951	42	56	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	184145256	184145256	7511	1	T	A	A	50	50	HMCN1	A	4	4
LAMB3	3914	broad.mit.edu	36	1	207868088	207868088	+	Missense_Mutation	SNP	G	C	C			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:207868088G>C	uc001hhg.1	-	c.1203C>G	c.(1201-1203)TGC>TGG	p.C401W	LAMB3_uc009xco.1_Missense_Mutation_p.C401W|LAMB3_uc001hhh.1_Missense_Mutation_p.C401W	NM_001017402	NP_001121113	Q13751	LAMB3_HUMAN	laminin, beta 3 precursor	401	Laminin EGF-like 3.				cell adhesion|epidermis development|hemidesmosome assembly		structural molecule activity			central_nervous_system(2)|large_intestine(1)|ovary(1)	4												OREG0014217	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.25	8.81927	9.500893	3	9	GG		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(81;0.0519)	Missense_Mutation	SNP	207868088	207868088	8935	1	G	C	C	46	46	LAMB3	C	3	3
OBSCN	84033	broad.mit.edu	36	1	226469937	226469937	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:226469937G>A	uc009xez.1	+	c.1879G>A	c.(1879-1881)GGT>AGT	p.G627S	OBSCN_uc001hsn.1_Missense_Mutation_p.G627S	NM_001098623	NP_001092093	Q5VST9	OBSCN_HUMAN	obscurin, cytoskeletal calmodulin and	627	Ig-like 6.				apoptosis|cell differentiation|induction of apoptosis by extracellular signals|multicellular organismal development|nerve growth factor receptor signaling pathway|protein phosphorylation|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|M band|Z disc	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity|Rho guanyl-nucleotide exchange factor activity|structural constituent of muscle|titin binding			large_intestine(7)|breast(5)|ovary(4)|skin(2)|stomach(1)|central_nervous_system(1)|pancreas(1)	21		Prostate(94;0.0405)								4006				0.5	12.00042	12.00042	4	4	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	226469937	226469937	11217	1	G	A	A	43	43	OBSCN	A	2	2
PGBD2	267002	broad.mit.edu	36	1	247179010	247179010	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:247179010G>A	uc001ifh.1	+	c.1604G>A	c.(1603-1605)GGG>GAG	p.G535E	PGBD2_uc001ifg.1_Missense_Mutation_p.G284E|PGBD2_uc009xhd.1_Missense_Mutation_p.G284E	NM_170725	NP_001017434	Q6P3X8	PGBD2_HUMAN	hypothetical protein LOC267002 isoform a	535										ovary(1)	1	all_cancers(71;3.33e-06)|all_epithelial(71;2.41e-06)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.0458)|Lung NSC(105;0.0494)|Melanoma(84;0.199)	all_cancers(173;0.012)												0.436242	196.051392	196.579733	65	84	GG		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(106;0.00989)		Missense_Mutation	SNP	247179010	247179010	12204	1	G	A	A	43	43	PGBD2	A	2	2
PGBD2	267002	broad.mit.edu	36	1	247179167	247179167	+	Missense_Mutation	SNP	G	T	T			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:247179167G>T	uc001ifh.1	+	c.1761G>T	c.(1759-1761)AGG>AGT	p.R587S	PGBD2_uc001ifg.1_Missense_Mutation_p.R336S|PGBD2_uc009xhd.1_Missense_Mutation_p.R336S	NM_170725	NP_001017434	Q6P3X8	PGBD2_HUMAN	hypothetical protein LOC267002 isoform a	587										ovary(1)	1	all_cancers(71;3.33e-06)|all_epithelial(71;2.41e-06)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.0458)|Lung NSC(105;0.0494)|Melanoma(84;0.199)	all_cancers(173;0.012)												0.530201	238.217539	238.335699	79	70	GG		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(106;0.00989)		Missense_Mutation	SNP	247179167	247179167	12204	1	G	T	T	43	43	PGBD2	T	3	3
DAB1	1600	broad.mit.edu	36	1	57307663	57307663	+	Silent	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:57307663G>A	uc001cys.1	-	c.621C>T	c.(619-621)CAC>CAT	p.H207H	DAB1_uc001cyt.1_Silent_p.H207H|DAB1_uc001cyq.1_Intron|DAB1_uc001cyr.1_Intron|DAB1_uc009vzw.1_Intron|DAB1_uc009vzx.1_Silent_p.H207H	NM_021080	NP_066566	O75553	DAB1_HUMAN	disabled homolog 1	207					cell differentiation|nervous system development					ovary(1)	1									p.H207H(RH41-Tumor)	395				0.53913	176.153659	176.308079	62	53	GG		KEEP	---	---	---	---	capture			Silent	SNP	57307663	57307663	4383	1	G	A	A	40	40	DAB1	A	1	1
SULF2	55959	broad.mit.edu	36	20	45819414	45819414	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr20:45819414C>T	uc002xto.1	-	c.101G>A	c.(100-102)AGG>AAG	p.R34K	SULF2_uc002xtp.1_Missense_Mutation_p.R34K|SULF2_uc002xtq.1_Missense_Mutation_p.R34K|SULF2_uc002xtr.1_Missense_Mutation_p.R34K|SULF2_uc010ghv.1_Missense_Mutation_p.R34K	NM_018837	NP_061325	Q8IWU5	SULF2_HUMAN	sulfatase 2 isoform a precursor	34					bone development|heparan sulfate proteoglycan metabolic process|kidney development|negative regulation of fibroblast growth factor receptor signaling pathway	cell surface|endoplasmic reticulum|extracellular space|Golgi stack	arylsulfatase activity|calcium ion binding			ovary(2)|breast(2)|pancreas(1)	5										709				0.347826	21.891169	22.36211	8	15	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	45819414	45819414	15891	20	C	T	T	24	24	SULF2	T	2	2
SLCO4A1	28231	broad.mit.edu	36	20	60762211	60762211	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr20:60762211C>T	uc002ydb.1	+	c.890C>T	c.(889-891)ACG>ATG	p.T297M	SLCO4A1_uc002ydc.1_Non-coding_Transcript	NM_016354	NP_057438	Q96BD0	SO4A1_HUMAN	solute carrier organic anion transporter family	297	Extracellular (Potential).				sodium-independent organic anion transport	integral to membrane|plasma membrane	thyroid hormone transmembrane transporter activity			ovary(1)	1	Breast(26;3.65e-08)					Pancreas(168;741 2006 10379 40139 45334)			p.T297M(CW2-Tumor)	402				0.234375	33.691825	37.824405	15	49	CC		KEEP	---	---	---	---	capture	BRCA - Breast invasive adenocarcinoma(19;2.33e-06)		Missense_Mutation	SNP	60762211	60762211	15226	20	C	T	T	19	19	SLCO4A1	T	1	1
KRTAP10-5	386680	broad.mit.edu	36	21	44824722	44824722	+	Silent	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr21:44824722C>T	uc002zfl.1	-	c.162G>A	c.(160-162)GCG>GCA	p.A54A	C21orf29_uc002zfe.1_Intron|C21orf29_uc010gpv.1_Intron	NM_198694	NP_941967	P60370	KR105_HUMAN	keratin associated protein 10-5	54	22 X 5 AA repeats of C-C-X(3).|2.					keratin filament					0														0.364865	75.006835	76.194611	27	47	CC		KEEP	---	---	---	---	capture			Silent	SNP	44824722	44824722	8827	21	C	T	T	23	23	KRTAP10-5	T	1	1
UGGT1	56886	broad.mit.edu	36	2	128660801	128660801	+	Nonsense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr2:128660801G>A	uc002tps.1	+	c.4434G>A	c.(4432-4434)TGG>TGA	p.W1478*	UGGT1_uc002tpr.1_Nonsense_Mutation_p.W1454*	NM_020120	NP_064505	Q9NYU2	UGGG1_HUMAN	UDP-glucose ceramide glucosyltransferase-like 1	1478	Glucosyltransferase (By similarity).				'de novo' posttranslational protein folding|post-translational protein modification|protein N-linked glycosylation via asparagine	endoplasmic reticulum lumen|ER-Golgi intermediate compartment	UDP-glucose:glycoprotein glucosyltransferase activity|unfolded protein binding			ovary(1)	1														0.486667	441.111698	441.158371	146	154	GG		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	128660801	128660801	17499	2	G	A	A	44	44	UGGT1	A	5	2
TTN	7273	broad.mit.edu	36	2	179279615	179279615	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:179279615C>T	uc002umr.1	-	c.25499G>A	c.(25498-25500)CGT>CAT	p.R8500H	TTN_uc002ums.1_Intron|TTN_uc010frc.1_Intron|TTN_uc010frd.1_Intron|TTN_uc002umz.1_Missense_Mutation_p.R5161H	NM_133378	NP_596869	Q8WZ42	TITIN_HUMAN	titin isoform N2-A	9427										ovary(58)|stomach(19)|large_intestine(17)|lung(16)|skin(16)|breast(10)|pancreas(7)|kidney(4)|central_nervous_system(3)|urinary_tract(2)|upper_aerodigestive_tract(1)	153										8722				0.468852	421.207342	421.46307	143	162	CC		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)		Missense_Mutation	SNP	179279615	179279615	17290	2	C	T	T	19	19	TTN	T	1	1
MYO1B	4430	broad.mit.edu	36	2	191935340	191935340	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:191935340C>T	uc010fsg.1	+	c.763C>T	c.(763-765)CGG>TGG	p.R255W	MYO1B_uc002usq.1_Missense_Mutation_p.R255W|MYO1B_uc002usr.1_Missense_Mutation_p.R255W|MYO1B_uc002uss.1_Missense_Mutation_p.R255W	NM_012223	NP_036355	O43795	MYO1B_HUMAN	myosin IB isoform 2	255	Myosin head-like.					myosin complex	actin binding|ATP binding|calmodulin binding|motor activity			central_nervous_system(5)|large_intestine(2)|ovary(1)	8														0.455696	106.889587	107.024578	36	43	CC		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(117;0.0112)|Epithelial(96;0.104)|all cancers(119;0.236)		Missense_Mutation	SNP	191935340	191935340	10464	2	C	T	T	27	27	MYO1B	T	1	1
COL6A3	1293	broad.mit.edu	36	2	237913840	237913840	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:237913840C>T	uc002vwl.2	-	c.8458G>A	c.(8458-8460)GTC>ATC	p.V2820I	COL6A3_uc002vwj.2_Missense_Mutation_p.V201I|COL6A3_uc002vwk.2_Missense_Mutation_p.V2653I|COL6A3_uc002vwm.2_Missense_Mutation_p.V2619I|COL6A3_uc002vwn.2_Missense_Mutation_p.V2620I|COL6A3_uc002vwo.2_Missense_Mutation_p.V2614I	NM_004369	NP_004360	P12111	CO6A3_HUMAN	alpha 3 type VI collagen isoform 1 precursor	2820	Nonhelical region.				axon guidance|cell adhesion|muscle organ development	collagen type VI|extracellular space	serine-type endopeptidase inhibitor activity			ovary(8)|central_nervous_system(6)|pancreas(1)	15		Breast(86;0.000301)|Renal(207;0.000966)|all_hematologic(139;0.067)|Ovarian(221;0.0694)|all_lung(227;0.0943)|Melanoma(123;0.203)												0.315217	74.538901	77.335097	29	63	CC		KEEP	---	---	---	---	capture		Epithelial(121;1.23e-21)|OV - Ovarian serous cystadenocarcinoma(60;1.34e-10)|Kidney(56;5.71e-09)|KIRC - Kidney renal clear cell carcinoma(57;1.51e-07)|BRCA - Breast invasive adenocarcinoma(100;0.00025)|Lung(119;0.0142)|LUSC - Lung squamous cell carcinoma(224;0.034)	Missense_Mutation	SNP	237913840	237913840	3839	2	C	T	T	19	19	COL6A3	T	1	1
NIT2	56954	broad.mit.edu	36	3	101540626	101540626	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr3:101540626C>T	uc003dtv.1	+	c.13C>T	c.(13-15)CGC>TGC	p.R5C		NM_020202	NP_064587	Q9NQR4	NIT2_HUMAN	nitrilase family, member 2	5	CN hydrolase.				nitrogen compound metabolic process		omega-amidase activity			ovary(1)	1														0.458689	513.24761	513.768017	161	190	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	101540626	101540626	10835	3	C	T	T	23	23	NIT2	T	1	1
DLG1	1739	broad.mit.edu	36	3	198405779	198405779	+	Missense_Mutation	SNP	C	G	G			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr3:198405779C>G	uc003fxn.2	-	c.397G>C	c.(397-399)GAA>CAA	p.E133Q	DLG1_uc003fxo.2_Missense_Mutation_p.E133Q|DLG1_uc010ial.1_Missense_Mutation_p.E133Q|DLG1_uc003fxp.2_Non-coding_Transcript|DLG1_uc010iam.1_Missense_Mutation_p.E133Q	NM_004087	NP_004078	Q12959	DLG1_HUMAN	discs, large homolog 1 isoform 2	133					actin filament organization|axon guidance|cell-cell adhesion|cortical actin cytoskeleton organization|endothelial cell proliferation|establishment or maintenance of cell polarity|interspecies interaction between organisms|mitotic cell cycle G1/S transition checkpoint|negative regulation of mitotic cell cycle|protein localization in plasma membrane|synaptic transmission|tight junction assembly	basolateral plasma membrane|cytosol|endoplasmic reticulum membrane|immunological synapse|MPP7-DLG1-LIN7 complex|nucleus|postsynaptic density|postsynaptic membrane|sarcolemma|tight junction	cytoskeletal protein binding|guanylate kinase activity|L27 domain binding|phosphatase binding|phosphoprotein phosphatase activity|potassium channel regulator activity|protein binding|protein C-terminus binding|protein kinase binding			ovary(3)	3	all_cancers(143;6.22e-10)|Ovarian(172;0.0418)|Breast(254;0.0589)	Lung NSC(153;0.133)												0.512821	215.311607	215.328682	60	57	CC		KEEP	---	---	---	---	capture	Epithelial(36;3.23e-24)|all cancers(36;2.15e-22)|OV - Ovarian serous cystadenocarcinoma(49;3.88e-19)|LUSC - Lung squamous cell carcinoma(58;1.51e-06)|Lung(62;1.95e-06)	GBM - Glioblastoma multiforme(46;0.0148)	Missense_Mutation	SNP	198405779	198405779	4734	3	C	G	G	32	32	DLG1	G	3	3
DCLK3	85443	broad.mit.edu	36	3	36754778	36754778	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr3:36754778C>T	uc003cgi.2	-	c.377G>A	c.(376-378)GGG>GAG	p.G126E		NM_033403	NP_208382	Q9C098	DCLK3_HUMAN	doublecortin-like kinase 3	126					protein phosphorylation	cytoplasm|nucleus	ATP binding|protein serine/threonine kinase activity			lung(3)|large_intestine(2)|ovary(1)|breast(1)|kidney(1)	8									p.G126E(JHUEM2-Tumor)	128				0.372159	393.863743	398.905591	131	221	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	36754778	36754778	4464	3	C	T	T	22	22	DCLK3	T	2	2
SLC6A20	54716	broad.mit.edu	36	3	45776404	45776404	+	Silent	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr3:45776404G>A	uc003cou.1	-	c.1578C>T	c.(1576-1578)AGC>AGT	p.S526S	SLC6A20_uc003cov.1_Silent_p.S489S|SLC6A20_uc003cow.1_Silent_p.S176S	NM_020208	NP_064593	Q9NP91	S6A20_HUMAN	solute carrier family 6, member 20 isoform 1	526	Extracellular (Potential).				cellular nitrogen compound metabolic process|glycine transport|proline transport	apical plasma membrane|integral to plasma membrane	amino acid transmembrane transporter activity|neurotransmitter:sodium symporter activity			ovary(2)	2														0.454106	267.31661	267.696455	94	113	GG		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(193;0.01)|KIRC - Kidney renal clear cell carcinoma(197;0.0225)|Kidney(197;0.0267)	Silent	SNP	45776404	45776404	15181	3	G	A	A	38	38	SLC6A20	A	1	1
PCDH10	57575	broad.mit.edu	36	4	134303659	134303659	+	Missense_Mutation	SNP	G	T	T			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr4:134303659G>T	uc003iha.1	+	c.2875G>T	c.(2875-2877)GTC>TTC	p.V959F		NM_032961	NP_116586	Q9P2E7	PCD10_HUMAN	protocadherin 10 isoform 1 precursor	959	Cytoplasmic (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(1)	1														0.47619	219.140294	219.212831	70	77	GG		KEEP	---	---	---	---	capture		LUSC - Lung squamous cell carcinoma(193;0.227)	Missense_Mutation	SNP	134303659	134303659	11927	4	G	T	T	48	48	PCDH10	T	3	3
DCLK2	166614	broad.mit.edu	36	4	151390280	151390280	+	Silent	SNP	C	G	G			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr4:151390280C>G	uc003ilo.2	+	c.2118C>G	c.(2116-2118)GTC>GTG	p.V706V	DCLK2_uc003ilm.2_Silent_p.V689V|DCLK2_uc003iln.2_Silent_p.V688V|DCLK2_uc003ilp.2_Non-coding_Transcript	NM_001040260	NP_001035350	Q8N568	DCLK2_HUMAN	doublecortin and CaM kinase-like 2 isoform a	689					intracellular signal transduction|protein phosphorylation	cytoplasm|cytoskeleton	ATP binding|protein serine/threonine kinase activity			ovary(3)	3	all_hematologic(180;0.151)					GBM(195;186 2215 13375 16801 37459)				411				0.402299	228.588092	230.047264	70	104	CC		KEEP	---	---	---	---	capture			Silent	SNP	151390280	151390280	4463	4	C	G	G	29	29	DCLK2	G	3	3
SLIT2	9353	broad.mit.edu	36	4	20152300	20152300	+	Silent	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr4:20152300C>T	uc003gpr.1	+	c.2103C>T	c.(2101-2103)CCC>CCT	p.P701P	SLIT2_uc003gps.1_Silent_p.P693P	NM_004787	NP_004778	O94813	SLIT2_HUMAN	slit homolog 2	701	LRRCT 3.				apoptosis involved in luteolysis|axon extension involved in axon guidance|branching morphogenesis of a tube|cell migration involved in sprouting angiogenesis|cellular response to heparin|cellular response to hormone stimulus|chemorepulsion involved in postnatal olfactory bulb interneuron migration|corticospinal neuron axon guidance through spinal cord|induction of negative chemotaxis|initiation of Roundabout signal transduction|motor axon guidance|negative regulation of actin filament polymerization|negative regulation of cell growth|negative regulation of cellular response to growth factor stimulus|negative regulation of chemokine-mediated signaling pathway|negative regulation of endothelial cell migration|negative regulation of lamellipodium assembly|negative regulation of mononuclear cell migration|negative regulation of neutrophil chemotaxis|negative regulation of protein phosphorylation|negative regulation of retinal ganglion cell axon guidance|negative regulation of small GTPase mediated signal transduction|negative regulation of smooth muscle cell chemotaxis|negative regulation of vascular permeability|positive regulation of apoptosis|positive regulation of axonogenesis|response to cortisol stimulus|retinal ganglion cell axon guidance|ureteric bud development	cell surface|cytoplasm|extracellular space|plasma membrane	calcium ion binding|GTPase inhibitor activity|heparin binding|laminin-1 binding|protein homodimerization activity|proteoglycan binding|Roundabout binding			central_nervous_system(4)|ovary(3)	7														0.416185	220.171064	221.231458	72	101	CC		KEEP	---	---	---	---	capture			Silent	SNP	20152300	20152300	15238	4	C	T	T	21	21	SLIT2	T	2	2
N4BP2	55728	broad.mit.edu	36	4	39795943	39795943	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr4:39795943G>A	uc003guy.2	+	c.1724G>A	c.(1723-1725)CGT>CAT	p.R575H	N4BP2_uc010ifq.1_Missense_Mutation_p.R495H|N4BP2_uc010ifr.1_Missense_Mutation_p.R495H	NM_018177	NP_060647	Q86UW6	N4BP2_HUMAN	Nedd4 binding protein 2	575						cytoplasm	ATP binding|ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity|endonuclease activity|protein binding			lung(3)|breast(2)|kidney(2)|ovary(1)	8										693				0.432432	138.787807	139.228203	48	63	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	39795943	39795943	10505	4	G	A	A	40	40	N4BP2	A	1	1
AP3S1	1176	broad.mit.edu	36	5	115205677	115205677	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr5:115205677G>A	uc003krl.1	+	c.44G>A	c.(43-45)CGG>CAG	p.R15Q	AP3S1_uc003krk.1_5'UTR|AP3S1_uc003krm.1_Missense_Mutation_p.R15Q|ATG12_uc003krh.1_5'Flank|ATG12_uc003kri.1_5'Flank|ATG12_uc003krj.1_5'Flank	NM_001284	NP_001275	Q92572	AP3S1_HUMAN	adaptor-related protein complex 3, sigma 1	15					insulin receptor signaling pathway|intracellular protein transport|vesicle-mediated transport	AP-type membrane coat adaptor complex|cytoplasmic vesicle membrane|Golgi apparatus|transport vesicle	protein binding|protein transporter activity				0		all_cancers(142;0.00377)|all_epithelial(76;0.000129)|Prostate(80;0.0132)|Ovarian(225;0.0776)|Lung NSC(810;0.245)												0.7	22.928632	23.28603	7	3	GG		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(64;1.08e-07)|Epithelial(69;1.11e-06)|all cancers(49;5.2e-05)	Missense_Mutation	SNP	115205677	115205677	759	5	G	A	A	39	39	AP3S1	A	1	1
WWC1	23286	broad.mit.edu	36	5	167804132	167804132	+	Missense_Mutation	SNP	A	G	G			TCGA-27-2523-01	TCGA-27-2523-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr5:167804132A>G	uc003lzu.1	+	c.2489A>G	c.(2488-2490)GAG>GGG	p.E830G	WWC1_uc003lzv.1_Missense_Mutation_p.E736G|WWC1_uc003lzw.1_Missense_Mutation_p.E629G|WWC1_uc010jjf.1_Missense_Mutation_p.E102G	NM_015238	NP_056053	Q8IX03	KIBRA_HUMAN	WW and C2 domain containing 1	830	Glu-rich.				cell migration|positive regulation of MAPKKK cascade|regulation of hippo signaling cascade|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus|perinuclear region of cytoplasm|ruffle membrane	protein binding|transcription coactivator activity			ovary(2)|breast(1)	3	Renal(175;0.000212)|Lung NSC(126;0.0875)|all_lung(126;0.166)	Medulloblastoma(196;0.0399)|all_neural(177;0.0577)												0.25	6.447832	7.906987	6	18	AA		KEEP	---	---	---	---	capture	Kidney(164;7.53e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.0364)|Epithelial(171;0.0765)|OV - Ovarian serous cystadenocarcinoma(192;0.0918)	Missense_Mutation	SNP	167804132	167804132	17985	5	A	G	G	11	11	WWC1	G	4	4
DOCK2	1794	broad.mit.edu	36	5	169438586	169438586	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr5:169438586C>T	uc003maf.1	+	c.5024C>T	c.(5023-5025)ACG>ATG	p.T1675M	DOCK2_uc010jjm.1_Missense_Mutation_p.T1167M|DOCK2_uc003mah.1_Missense_Mutation_p.T231M	NM_004946	NP_004937	Q92608	DOCK2_HUMAN	dedicator of cytokinesis 2	1675					actin cytoskeleton organization|regulation of defense response to virus by virus|viral reproduction	cytoskeleton|cytosol|endomembrane system|membrane	electron carrier activity|GTP binding|GTPase binding|heme binding|Rac guanyl-nucleotide exchange factor activity|T cell receptor binding			ovary(5)|pancreas(2)	7	Renal(175;0.000159)|Lung NSC(126;0.0221)|all_lung(126;0.0337)	Medulloblastoma(196;0.0399)|all_neural(177;0.0966)												0.390041	257.359495	259.921617	94	147	CC		KEEP	---	---	---	---	capture	Kidney(164;7.53e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)		Missense_Mutation	SNP	169438586	169438586	4871	5	C	T	T	19	19	DOCK2	T	1	1
WDR27	253769	broad.mit.edu	36	6	169778399	169778399	+	Missense_Mutation	SNP	T	C	C			TCGA-27-2523-01	TCGA-27-2523-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr6:169778399T>C	uc010kkw.1	-	c.1996A>G	c.(1996-1998)ATT>GTT	p.I666V	WDR27_uc003qwv.1_Intron|WDR27_uc003qwx.2_Missense_Mutation_p.I666V|WDR27_uc003qwy.2_Missense_Mutation_p.I539V	NM_182552	NP_872358	A2RRH5	WDR27_HUMAN	WD repeat domain 27	636										pancreas(1)	1		Breast(66;1.53e-05)|Ovarian(120;0.216)												0.439024	115.367694	115.636226	36	46	TT		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(33;6.48e-20)|BRCA - Breast invasive adenocarcinoma(81;3.56e-07)|GBM - Glioblastoma multiforme(31;0.00168)	Missense_Mutation	SNP	169778399	169778399	17857	6	T	C	C	50	50	WDR27	C	4	4
FAM126A	84668	broad.mit.edu	36	7	22990125	22990125	+	Nonsense_Mutation	SNP	G	T	T			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr7:22990125G>T	uc003svm.2	-	c.116C>A	c.(115-117)TCA>TAA	p.S39*	FAM126A_uc003svn.2_5'UTR	NM_032581	NP_115970	Q9BYI3	HYCCI_HUMAN	family with sequence similarity 126, member A	39						cytoplasm|membrane	signal transducer activity			central_nervous_system(1)	1														0.245033	84.694519	93.641218	37	114	GG		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	22990125	22990125	5626	7	G	T	T	45	45	FAM126A	T	5	3
NAPRT1	93100	broad.mit.edu	36	8	144728541	144728541	+	Missense_Mutation	SNP	A	C	C			TCGA-27-2523-01	TCGA-27-2523-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr8:144728541A>C	uc003yyo.2	-	c.1409T>G	c.(1408-1410)GTG>GGG	p.V470G	C8orf73_uc010mff.1_5'Flank|C8orf73_uc010mfg.1_5'Flank|NAPRT1_uc003yyl.1_Missense_Mutation_p.V446G|NAPRT1_uc003yym.2_Missense_Mutation_p.V470G|NAPRT1_uc003yyn.2_Splice_Site_SNP_p.Q469_splice	NM_145201	NP_660202	Q6XQN6	PNCB_HUMAN	nicotinate phosphoribosyltransferase domain	470					nicotinamide metabolic process|nicotinate nucleotide salvage|response to oxidative stress	cytosol|Golgi apparatus|nucleus	nicotinate phosphoribosyltransferase activity|nicotinate-nucleotide diphosphorylase (carboxylating) activity			ovary(1)	1	all_cancers(97;6.49e-11)|all_epithelial(106;4.73e-09)|Lung NSC(106;0.000202)|all_lung(105;0.000548)|Ovarian(258;0.014)|Acute lymphoblastic leukemia(118;0.155)									3				0.238095	6.326456	7.69206	5	16	AA		KEEP	---	---	---	---	capture	Colorectal(110;0.134)|BRCA - Breast invasive adenocarcinoma(115;0.146)		Missense_Mutation	SNP	144728541	144728541	10561	8	A	C	C	6	6	NAPRT1	C	4	4
SLC39A4	55630	broad.mit.edu	36	8	145612923	145612923	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr8:145612923G>A	uc003zcq.1	-	c.59C>T	c.(58-60)GCG>GTG	p.A20V	SLC39A4_uc003zco.1_5'Flank|SLC39A4_uc003zcp.1_5'Flank	NM_130849	NP_570901	Q6P5W5	S39A4_HUMAN	solute carrier family 39 (zinc transporter),	20						cytoplasmic membrane-bounded vesicle|integral to membrane|recycling endosome membrane	zinc ion transmembrane transporter activity				0	all_cancers(97;6.64e-12)|all_epithelial(106;2.89e-10)|Lung NSC(106;5.7e-05)|all_lung(105;0.000174)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)													0.5	23.199732	23.199732	8	8	GG		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(54;1.08e-41)|Epithelial(56;1.12e-40)|all cancers(56;8.17e-36)|BRCA - Breast invasive adenocarcinoma(115;0.0407)|Colorectal(110;0.055)		Missense_Mutation	SNP	145612923	145612923	15117	8	G	A	A	38	38	SLC39A4	A	1	1
ARFGEF1	10565	broad.mit.edu	36	8	68302871	68302871	+	Missense_Mutation	SNP	T	C	C			TCGA-27-2523-01	TCGA-27-2523-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr8:68302871T>C	uc003xxo.1	-	c.3472A>G	c.(3472-3474)ACG>GCG	p.T1158A	ARFGEF1_uc003xxl.1_Missense_Mutation_p.T612A|ARFGEF1_uc003xxn.1_Missense_Mutation_p.T141A	NM_006421	NP_006412	Q9Y6D6	BIG1_HUMAN	brefeldin A-inhibited guanine	1158					exocytosis|regulation of ARF protein signal transduction	cytoplasm	ARF guanyl-nucleotide exchange factor activity|myosin binding			ovary(4)|upper_aerodigestive_tract(1)|large_intestine(1)|lung(1)|kidney(1)	8	Breast(64;0.214)	Lung NSC(129;0.0908)|all_lung(136;0.152)								932				0.451852	193.862703	194.134615	61	74	TT		KEEP	---	---	---	---	capture	Epithelial(68;0.0043)|OV - Ovarian serous cystadenocarcinoma(28;0.00578)|all cancers(69;0.0173)|BRCA - Breast invasive adenocarcinoma(89;0.206)		Missense_Mutation	SNP	68302871	68302871	863	8	T	C	C	59	59	ARFGEF1	C	4	4
PAPPA	5069	broad.mit.edu	36	9	118037730	118037730	+	Missense_Mutation	SNP	G	A	A			TCGA-27-2523-01	TCGA-27-2523-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr9:118037730G>A	uc004bjn.1	+	c.2725G>A	c.(2725-2727)GTA>ATA	p.V909I		NM_002581	NP_002572	Q13219	PAPP1_HUMAN	pregnancy-associated plasma protein A	909					cell differentiation|female pregnancy	cytoplasm|extracellular region|membrane	metalloendopeptidase activity|zinc ion binding			ovary(4)|pancreas(1)	5									p.V909I(RKO-Tumor)	611				0.432056	362.059671	363.213523	124	163	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	118037730	118037730	11849	9	G	A	A	40	40	PAPPA	A	1	1
GABRQ	55879	broad.mit.edu	36	X	151570700	151570700	+	Silent	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chrX:151570700C>T	uc004ffp.1	+	c.957C>T	c.(955-957)CTC>CTT	p.L319L		NM_018558	NP_061028	Q9UN88	GBRT_HUMAN	gamma-aminobutyric acid (GABA) receptor, theta	319						cell junction|chloride channel complex|integral to plasma membrane|postsynaptic membrane	chloride channel activity|extracellular ligand-gated ion channel activity|GABA-A receptor activity|neurotransmitter transporter activity			ovary(2)|pancreas(1)	3	Acute lymphoblastic leukemia(192;6.56e-05)													0.934959	386.914885	406.782859	115	8	CC		KEEP	---	---	---	---	capture			Silent	SNP	151570700	151570700	6426	23	C	T	T	30	30	GABRQ	T	2	2
RBM3	5935	broad.mit.edu	36	X	48319872	48319872	+	Missense_Mutation	SNP	T	G	G			TCGA-27-2523-01	TCGA-27-2523-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chrX:48319872T>G	uc004dkf.1	+	c.349T>G	c.(349-351)TAT>GAT	p.Y117D	RBM3_uc004dkd.1_Non-coding_Transcript|RBM3_uc004dkg.2_Missense_Mutation_p.Y117D	NM_006743	NP_006734	P98179	RBM3_HUMAN	RNA binding motif protein 3	117	Gly-rich.				positive regulation of translation	dendrite|nucleus	nucleotide binding|RNA binding			ovary(1)	1														0.428571	7.923182	7.954414	3	4	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	48319872	48319872	13591	23	T	G	G	57	57	RBM3	G	4	4
PCDH11Y	83259	broad.mit.edu	36	Y	5665715	5665715	+	Missense_Mutation	SNP	C	T	T			TCGA-27-2523-01	TCGA-27-2523-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chrY:5665715C>T	uc004fqo.1	+	c.3755C>T	c.(3754-3756)TCT>TTT	p.S1252F		NM_032973	NP_116755	Q9BZA8	PC11Y_HUMAN	protocadherin 11 Y-linked isoform c	1252	Cytoplasmic (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding				0														0.936047	542.009264	568.109009	161	11	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	5665715	5665715	11929	24	C	T	T	32	32	PCDH11Y	T	2	2
PIK3R2	5296	broad.mit.edu	36	19	18138106	18138106	+	Frame_Shift_Del	DEL	T	-	-			TCGA-27-2523-01	TCGA-27-2523-01										Phase_I	Unspecified				Illumina GAIIx	g.chr19:18138106_18138106delT	uc002nia.1	+	c.1553_1553delT	c.(1552-1554)ATGfs	p.M518fs	PIK3R2_uc002nib.1_Non-coding_Transcript|PIK3R2_uc010ebi.1_Non-coding_Transcript	NM_005027	NP_005018	O00459	P85B_HUMAN	phosphoinositide-3-kinase, regulatory subunit 2	518					fibroblast growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|negative regulation of anti-apoptosis|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|platelet activation|regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction|T cell costimulation|T cell receptor signaling pathway	phosphatidylinositol 3-kinase complex	GTPase activator activity|phosphatidylinositol 3-kinase regulator activity|protein binding			lung(2)|central_nervous_system(1)|pancreas(1)	4										186				0.30			21	48				---	---	---	---	capture_indel			Frame_Shift_Del	DEL	18138106	18138106	12343	19	T	-	-	51	51	PIK3R2	-	5	5
