Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_status	validation_method	validation_tumor_sample	validation_alt_allele
NPHP4	261734	broad.mit.edu	37	1	5939835	5939836	+	Intron	INS	-	CA	CA	rs149843560	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:5939835_5939836insCA	uc001alq.1	-						NPHP4_uc001als.1_Intron|NPHP4_uc009vlt.1_Intron|NPHP4_uc001alt.1_Intron	NM_015102	NP_055917			nephroretinin						actin cytoskeleton organization|cell-cell adhesion|signal transduction|visual behavior	cell-cell junction|centrosome|cilium|microtubule basal body	protein binding|structural molecule activity			pancreas(1)	1	Ovarian(185;0.0634)	all_cancers(23;7.53e-41)|all_epithelial(116;3.96e-23)|all_lung(118;5.12e-09)|all_hematologic(16;5.45e-07)|Lung NSC(185;5.49e-07)|all_neural(13;3.21e-06)|Acute lymphoblastic leukemia(12;3.44e-05)|Breast(487;0.000601)|Renal(390;0.0007)|Colorectal(325;0.00113)|Hepatocellular(190;0.00213)|Glioma(11;0.00223)|Myeloproliferative disorder(586;0.0256)|Ovarian(437;0.04)|Lung SC(97;0.128)|Medulloblastoma(700;0.213)		Epithelial(90;1.69e-36)|GBM - Glioblastoma multiforme(13;5.07e-29)|OV - Ovarian serous cystadenocarcinoma(86;1.05e-19)|Colorectal(212;4.54e-07)|COAD - Colon adenocarcinoma(227;3.14e-05)|Kidney(185;0.00012)|BRCA - Breast invasive adenocarcinoma(365;0.00102)|KIRC - Kidney renal clear cell carcinoma(229;0.00179)|STAD - Stomach adenocarcinoma(132;0.00472)|READ - Rectum adenocarcinoma(331;0.0649)														---	---	---	---
FNDC5	252995	broad.mit.edu	37	1	33330042	33330043	+	Intron	INS	-	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:33330042_33330043insT	uc001bwf.1	-						FNDC5_uc001bwe.2_Intron	NM_153756	NP_715637			fibronectin type III domain containing 5							integral to membrane|peroxisomal membrane				ovary(1)	1		Myeloproliferative disorder(586;0.0393)|all_neural(195;0.186)																---	---	---	---
RAP1A	5906	broad.mit.edu	37	1	112190796	112190797	+	Intron	INS	-	GTGTGT	GTGTGT	rs143658994	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:112190796_112190797insGTGTGT	uc001ebi.2	+						RAP1A_uc001ebk.2_Intron|RAP1A_uc001ebl.2_Intron|RAP1A_uc001ebm.2_Intron	NM_002884	NP_002875			RAP1A, member of RAS oncogene family precursor						activation of MAPKK activity|blood coagulation|energy reserve metabolic process|nerve growth factor receptor signaling pathway|regulation of insulin secretion	cytosol|plasma membrane	GTP binding|GTPase activity				0		all_cancers(81;6.79e-06)|all_epithelial(167;2.42e-05)|all_lung(203;0.000105)|Lung NSC(277;0.00021)		Lung(183;0.0183)|Colorectal(144;0.0418)|LUSC - Lung squamous cell carcinoma(189;0.0966)|all cancers(265;0.098)|Epithelial(280;0.0981)|COAD - Colon adenocarcinoma(174;0.141)														---	---	---	---
Unknown	0	broad.mit.edu	37	2	64603286	64603288	+	IGR	DEL	CAC	-	-	rs141929982		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:64603286_64603288delCAC								PELI1 (231681 upstream) : HSPC159 (78039 downstream)																																			---	---	---	---
SFTPB	6439	broad.mit.edu	37	2	85893617	85893618	+	Intron	DEL	TG	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:85893617_85893618delTG	uc002sqh.2	-						SFTPB_uc002sqi.2_Intron|SFTPB_uc002sqj.2_Intron	NM_198843	NP_942140			surfactant, pulmonary-associated protein B						organ morphogenesis|respiratory gaseous exchange|sphingolipid metabolic process	extracellular space|lysosome				ovary(1)|central_nervous_system(1)	2																		---	---	---	---
DYNC1I2	1781	broad.mit.edu	37	2	172584624	172584624	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:172584624delT	uc002uha.1	+						DYNC1I2_uc002uhc.2_Intron|DYNC1I2_uc002uhb.1_Intron|DYNC1I2_uc010zds.1_Intron|DYNC1I2_uc002uhe.1_Intron|DYNC1I2_uc002uhf.1_Intron|DYNC1I2_uc010zdt.1_Intron|DYNC1I2_uc002uhg.1_Intron|DYNC1I2_uc010zdu.1_Intron	NM_001378	NP_001369			dynein, cytoplasmic 1, intermediate chain 2						G2/M transition of mitotic cell cycle|interspecies interaction between organisms|microtubule-based movement|transport	centrosome|cytosol|dynein complex|microtubule|vesicle	microtubule motor activity			ovary(1)	1			OV - Ovarian serous cystadenocarcinoma(117;0.198)															---	---	---	---
MDH1B	130752	broad.mit.edu	37	2	207604137	207604137	+	Intron	DEL	A	-	-	rs141240854		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:207604137delA	uc002vbs.2	-						MDH1B_uc010ziw.1_Intron|MDH1B_uc010fui.2_Intron|MDH1B_uc010fuj.2_Intron|MDH1B_uc002vbt.2_Intron	NM_001039845	NP_001034934			malate dehydrogenase 1B, NAD (soluble)						carbohydrate metabolic process|malate metabolic process|tricarboxylic acid cycle		binding|malate dehydrogenase activity			ovary(3)|kidney(1)	4				LUSC - Lung squamous cell carcinoma(261;0.0763)|Epithelial(149;0.131)|Lung(261;0.145)														---	---	---	---
UBP1	7342	broad.mit.edu	37	3	33453380	33453380	+	Intron	DEL	T	-	-	rs150973041		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:33453380delT	uc003cfq.3	-						UBP1_uc003cfr.3_Intron|UBP1_uc010hga.2_Intron	NM_014517	NP_055332			upstream binding protein 1 (LBP-1a) isoform a						negative regulation of transcription, DNA-dependent|regulation of transcription from RNA polymerase II promoter|viral genome replication	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity			kidney(2)	2																		---	---	---	---
FRMD4B	23150	broad.mit.edu	37	3	69265580	69265580	+	Intron	DEL	C	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:69265580delC	uc003dnv.2	-						FRMD4B_uc003dnw.2_Intron|FRMD4B_uc003dnx.1_Intron|FRMD4B_uc011bga.1_Intron	NM_015123	NP_055938			FERM domain containing 4B							cytoplasm|cytoskeleton	binding			ovary(3)|central_nervous_system(1)	4		Lung NSC(201;0.0138)|Prostate(884;0.11)		BRCA - Breast invasive adenocarcinoma(55;0.000201)|Epithelial(33;0.00141)|LUSC - Lung squamous cell carcinoma(21;0.00999)|Lung(16;0.0182)														---	---	---	---
Unknown	0	broad.mit.edu	37	3	98153144	98153144	+	IGR	DEL	A	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:98153144delA								OR5K3 (42670 upstream) : OR5K1 (35277 downstream)																																			---	---	---	---
MRPL3	11222	broad.mit.edu	37	3	131208669	131208669	+	Intron	DEL	A	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:131208669delA	uc003eoh.2	-						MRPL3_uc011blo.1_Intron|MRPL3_uc011blp.1_Intron	NM_007208	NP_009139			mitochondrial ribosomal protein L3						translation	mitochondrial large ribosomal subunit	RNA binding|structural constituent of ribosome				0																		---	---	---	---
CP	1356	broad.mit.edu	37	3	148899609	148899609	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:148899609delT	uc003ewy.3	-						CP_uc011bnr.1_Intron|CP_uc003eww.3_5'Flank|CP_uc003ewx.3_Intron|CP_uc003ewz.2_Intron	NM_000096	NP_000087			ceruloplasmin precursor						cellular iron ion homeostasis|copper ion transport|transmembrane transport	extracellular space	chaperone binding|ferroxidase activity			ovary(1)	1		Prostate(884;0.00217)|Hepatocellular(537;0.00826)|Myeloproliferative disorder(1037;0.0122)|all_neural(597;0.0189)|Melanoma(1037;0.152)	LUSC - Lung squamous cell carcinoma(72;0.0473)|Lung(72;0.0607)		Drotrecogin alfa(DB00055)													---	---	---	---
WWTR1	25937	broad.mit.edu	37	3	149374542	149374553	+	Intron	DEL	TCTCTCTCTTTC	-	-	rs140515074	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:149374542_149374553delTCTCTCTCTTTC	uc003exe.2	-						WWTR1_uc003exf.2_Intron|WWTR1_uc011bns.1_Intron|WWTR1_uc003exh.2_Intron|uc010hvg.1_5'Flank|uc003exi.1_5'Flank	NM_015472	NP_056287			WW domain containing transcription regulator 1						hippo signaling cascade|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of catenin import into nucleus|negative regulation of protein kinase activity|negative regulation of protein phosphorylation|positive regulation of cell proliferation|positive regulation of epithelial to mesenchymal transition|regulation of SMAD protein import into nucleus|stem cell division|transcription, DNA-dependent	cytoplasm	transcription coactivator activity			breast(3)|skin(1)	4			LUSC - Lung squamous cell carcinoma(72;0.0378)|Lung(72;0.048)															---	---	---	---
TNIK	23043	broad.mit.edu	37	3	170841527	170841528	+	Intron	INS	-	AGT	AGT			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:170841527_170841528insAGT	uc003fhh.2	-						TNIK_uc003fhi.2_Intron|TNIK_uc003fhj.2_Intron|TNIK_uc003fhk.2_Intron|TNIK_uc003fhl.2_Intron|TNIK_uc003fhm.2_Intron|TNIK_uc003fhn.2_Intron|TNIK_uc003fho.2_Intron	NM_015028	NP_055843			TRAF2 and NCK interacting kinase isoform 1						actin cytoskeleton reorganization|activation of JNKK activity|protein autophosphorylation|regulation of dendrite morphogenesis|Wnt receptor signaling pathway	cytoskeleton|nucleus|recycling endosome	ATP binding|protein binding|protein serine/threonine kinase activity|small GTPase regulator activity			ovary(4)|large_intestine(1)	5	all_cancers(22;2.55e-19)|all_lung(20;2.22e-14)|Ovarian(172;0.00197)|Breast(254;0.122)		LUSC - Lung squamous cell carcinoma(14;3.57e-14)|Lung(28;9.39e-14)															---	---	---	---
WDR53	348793	broad.mit.edu	37	3	196281881	196281882	+	Intron	INS	-	AGGTAGAATTA	AGGTAGAATTA	rs147559216	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:196281881_196281882insAGGTAGAATTA	uc003fwt.2	-							NM_182627	NP_872433			WD repeat domain 53											breast(1)|skin(1)	2	all_cancers(143;8.88e-09)|Ovarian(172;0.0634)|Breast(254;0.135)		Epithelial(36;1.6e-23)|all cancers(36;1.54e-21)|OV - Ovarian serous cystadenocarcinoma(49;1.29e-18)|LUSC - Lung squamous cell carcinoma(58;1.51e-06)|Lung(62;1.95e-06)	GBM - Glioblastoma multiforme(46;0.00326)														---	---	---	---
UBA6	55236	broad.mit.edu	37	4	68566892	68566892	+	5'Flank	DEL	G	-	-	rs66862981		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr4:68566892delG	uc003hdg.3	-						UBA6_uc003hdi.2_5'Flank|UBA6_uc003hdj.2_5'Flank|LOC550112_uc003hdl.3_5'Flank|LOC550112_uc003hdk.2_5'Flank	NM_018227	NP_060697			ubiquitin-activating enzyme E1-like 2						protein ubiquitination|ubiquitin-dependent protein catabolic process	cytoplasm	ATP binding|FAT10 activating enzyme activity|ligase activity|protein binding				0																OREG0016213	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	---	---	---	---
SNX25	83891	broad.mit.edu	37	4	186180379	186180379	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr4:186180379delT	uc003ixh.2	+							NM_031953	NP_114159			sorting nexin 25						cell communication|protein transport	endosome membrane	phosphatidylinositol binding|signal transducer activity			ovary(2)|breast(2)|pancreas(1)	5		all_lung(41;1.03e-13)|Lung NSC(41;2.5e-13)|Hepatocellular(41;0.00826)|Colorectal(36;0.00886)|Renal(120;0.00988)|Prostate(90;0.0235)|all_hematologic(60;0.0592)|all_neural(102;0.243)		all cancers(43;2.13e-24)|Epithelial(43;6.15e-22)|OV - Ovarian serous cystadenocarcinoma(60;5.6e-11)|BRCA - Breast invasive adenocarcinoma(30;0.00013)|Colorectal(24;0.000165)|GBM - Glioblastoma multiforme(59;0.000357)|COAD - Colon adenocarcinoma(29;0.000887)|STAD - Stomach adenocarcinoma(60;0.00118)|LUSC - Lung squamous cell carcinoma(40;0.0129)|READ - Rectum adenocarcinoma(43;0.228)														---	---	---	---
JMY	133746	broad.mit.edu	37	5	78579899	78579903	+	Intron	DEL	TTTTA	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr5:78579899_78579903delTTTTA	uc003kfx.3	+						JMY_uc003kfw.1_Intron	NM_152405	NP_689618			junction-mediating and regulatory protein						'de novo' actin filament nucleation|actin polymerization-dependent cell motility|Arp2/3 complex-mediated actin nucleation|cell cycle arrest|DNA repair|induction of apoptosis|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of transcription from RNA polymerase II promoter	cell leading edge|cytoplasm|cytoskeleton|nucleus	actin binding|transcription coactivator activity				0		all_lung(232;0.00051)|Lung NSC(167;0.00131)|Ovarian(174;0.0261)|Prostate(461;0.191)		OV - Ovarian serous cystadenocarcinoma(54;4.45e-45)|Epithelial(54;5.85e-40)|all cancers(79;2.89e-35)														---	---	---	---
FAM153B	202134	broad.mit.edu	37	5	175530031	175530031	+	Intron	DEL	G	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr5:175530031delG	uc003mdk.2	+							NM_001079529	NP_001072997			hypothetical protein LOC202134											ovary(1)	1	all_cancers(89;0.00406)|Renal(175;0.000269)|Lung NSC(126;0.0103)|all_lung(126;0.0164)	Medulloblastoma(196;0.0208)|all_neural(177;0.0416)|all_hematologic(541;0.214)	Kidney(164;3.85e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000183)	Kidney(146;0.0965)														---	---	---	---
TCP11	6954	broad.mit.edu	37	6	35087332	35087333	+	Intron	INS	-	AGG	AGG	rs138110679	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:35087332_35087333insAGG	uc003okd.2	-						TCP11_uc003ojz.1_Intron|TCP11_uc003oka.2_Intron|TCP11_uc003okb.2_Intron|TCP11_uc003okc.2_Intron|TCP11_uc011dsu.1_Intron|TCP11_uc011dsv.1_Intron|TCP11_uc011dsw.1_Intron	NM_001093728	NP_001087197			t-complex 11 isoform 1						cell differentiation|multicellular organismal development|spermatogenesis	integral to membrane				ovary(3)|skin(2)	5																		---	---	---	---
CAPN11	11131	broad.mit.edu	37	6	44149154	44149157	+	Intron	DEL	CACA	-	-	rs150779569		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:44149154_44149157delCACA	uc003owt.1	+						CAPN11_uc011dvn.1_Intron	NM_007058	NP_008989			calpain 11						proteolysis	acrosomal vesicle	calcium ion binding|calcium-dependent cysteine-type endopeptidase activity			ovary(1)|breast(1)	2	all_cancers(18;3.19e-06)|Lung NSC(15;0.00108)|all_lung(25;0.00278)|Hepatocellular(11;0.00908)|Ovarian(13;0.0273)		Colorectal(64;0.00337)|COAD - Colon adenocarcinoma(64;0.00536)															---	---	---	---
COL12A1	1303	broad.mit.edu	37	6	75855328	75855328	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:75855328delT	uc003phs.2	-						COL12A1_uc003pht.2_Intron	NM_004370	NP_004361			collagen, type XII, alpha 1 long isoform						cell adhesion|collagen fibril organization|skeletal system development	collagen type XII|extracellular space	extracellular matrix structural constituent conferring tensile strength			ovary(6)|large_intestine(1)|breast(1)|skin(1)	9																		---	---	---	---
ZUFSP	221302	broad.mit.edu	37	6	116982067	116982068	+	Intron	INS	-	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:116982067_116982068insT	uc003pxf.1	-						ZUFSP_uc010kef.1_Intron	NM_145062	NP_659499			zinc finger with UFM1-specific peptidase domain							intracellular	zinc ion binding			skin(1)	1				GBM - Glioblastoma multiforme(226;0.0258)|all cancers(137;0.0368)|OV - Ovarian serous cystadenocarcinoma(136;0.0464)|Epithelial(106;0.186)														---	---	---	---
TMEM181	57583	broad.mit.edu	37	6	159049261	159049262	+	Intron	DEL	TG	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:159049261_159049262delTG	uc003qrm.3	+						TMEM181_uc010kjr.1_Intron	NM_020823	NP_065874			G protein-coupled receptor 178						pathogenesis	integral to membrane	toxin binding			ovary(2)|central_nervous_system(1)	3		Breast(66;0.000776)|Ovarian(120;0.0303)		OV - Ovarian serous cystadenocarcinoma(65;8.15e-18)|BRCA - Breast invasive adenocarcinoma(81;1.38e-05)														---	---	---	---
PMS2L4	5382	broad.mit.edu	37	7	66762433	66762433	+	Intron	DEL	A	-	-	rs68053451		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:66762433delA	uc003tvo.2	-						PMS2L4_uc003tvq.2_Intron|PMS2L4_uc003tvr.3_Intron|PMS2L4_uc003tvs.3_Intron					Homo sapiens cDNA clone IMAGE:4081618.												0																		---	---	---	---
C7orf63	79846	broad.mit.edu	37	7	89929478	89929479	+	Intron	INS	-	T	T	rs35447757		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:89929478_89929479insT	uc010lep.2	+						C7orf63_uc003ukf.2_Intron|C7orf63_uc003ukg.2_Intron|C7orf63_uc011khj.1_Intron|C7orf63_uc011khk.1_Intron	NM_001039706	NP_001034795			hypothetical protein LOC79846 isoform 1								binding			ovary(1)	1																		---	---	---	---
SPDYE6	729597	broad.mit.edu	37	7	101994098	101994098	+	Intron	DEL	C	-	-	rs79613475		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:101994098delC	uc011kkp.1	-						SPDYE6_uc003uzb.2_5'Flank	NM_001146210	NP_001139682			speedy homolog E6												0																		---	---	---	---
SLC13A1	6561	broad.mit.edu	37	7	122755345	122755345	+	3'UTR	DEL	A	-	-	rs10709989		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:122755345delA	uc003vkm.2	-	15					SLC13A1_uc010lks.2_3'UTR	NM_022444	NP_071889			solute carrier family 13 (sodium/sulfate							integral to membrane|plasma membrane	sodium:sulfate symporter activity			ovary(2)	2					Succinic acid(DB00139)													---	---	---	---
GIMAP2	26157	broad.mit.edu	37	7	150384031	150384032	+	Intron	INS	-	AA	AA	rs76731830		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:150384031_150384032insAA	uc003who.2	+						GIMAP1_uc003whp.2_Intron	NM_015660	NP_056475			GTPase, IMAP family member 2							integral to membrane	GTP binding			skin(1)	1			OV - Ovarian serous cystadenocarcinoma(82;0.0145)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)														---	---	---	---
ADHFE1	137872	broad.mit.edu	37	8	67369551	67369552	+	Intron	INS	-	A	A	rs148427504		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr8:67369551_67369552insA	uc003xwb.3	+						ADHFE1_uc003xwd.3_Intron|ADHFE1_uc003xwc.3_Intron|ADHFE1_uc003xwe.3_Intron|ADHFE1_uc003xwf.3_Intron|ADHFE1_uc011les.1_Intron	NM_144650	NP_653251			alcohol dehydrogenase, iron containing, 1						2-oxoglutarate metabolic process|molecular hydrogen transport	mitochondrial matrix	hydroxyacid-oxoacid transhydrogenase activity|metal ion binding			ovary(1)|lung(1)|breast(1)|skin(1)	4		Lung NSC(129;0.197)	Epithelial(68;0.0321)|all cancers(69;0.0751)|BRCA - Breast invasive adenocarcinoma(89;0.0855)|OV - Ovarian serous cystadenocarcinoma(28;0.226)															---	---	---	---
Unknown	0	broad.mit.edu	37	9	1011394	1011394	+	IGR	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:1011394delT								DMRT3 (19662 upstream) : DMRT2 (38464 downstream)																																			---	---	---	---
JMJD1C	221037	broad.mit.edu	37	10	65139866	65139866	+	Intron	DEL	T	-	-	rs34420480		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr10:65139866delT	uc001jmn.2	-						JMJD1C_uc009xpi.2_Intron|JMJD1C_uc001jmr.1_3'UTR	NM_032776	NP_116165			jumonji domain containing 1C isoform a						blood coagulation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleoplasm	histone demethylase activity (H3-K9 specific)|metal ion binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|thyroid hormone receptor binding			ovary(4)|breast(1)|central_nervous_system(1)	6	Prostate(12;0.0119)|all_hematologic(501;0.191)																	---	---	---	---
FIBP	9158	broad.mit.edu	37	11	65653640	65653641	+	Intron	INS	-	A	A	rs5792375		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr11:65653640_65653641insA	uc001ogd.2	-						FIBP_uc009yqu.2_Intron|FIBP_uc001oge.2_Intron	NM_198897	NP_942600			FGF intracellular binding protein isoform a						fibroblast growth factor receptor signaling pathway	endomembrane system|membrane|microsome|mitochondrion|nucleus	fibroblast growth factor binding			ovary(1)	1				READ - Rectum adenocarcinoma(159;0.166)														---	---	---	---
ELMOD1	55531	broad.mit.edu	37	11	107518030	107518030	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr11:107518030delT	uc010rvs.1	+						ELMOD1_uc001pjm.2_Intron|ELMOD1_uc010rvt.1_Intron	NM_018712	NP_061182			ELMO/CED-12 domain containing 1 isoform 1						phagocytosis	cytoskeleton	GTPase activator activity				0		Melanoma(852;0.000288)|Acute lymphoblastic leukemia(157;0.000966)|all_hematologic(158;0.00301)|all_epithelial(67;0.00304)|Breast(348;0.104)		BRCA - Breast invasive adenocarcinoma(274;3.4e-05)|Epithelial(105;0.00027)|all cancers(92;0.00481)														---	---	---	---
PDE3A	5139	broad.mit.edu	37	12	20523326	20523334	+	Intron	DEL	TTTTTTTTG	-	-	rs111407502	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:20523326_20523334delTTTTTTTTG	uc001reh.1	+							NM_000921	NP_000912			phosphodiesterase 3A						lipid metabolic process|platelet activation|signal transduction	cytosol|integral to membrane	3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-GMP phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|metal ion binding			ovary(3)|upper_aerodigestive_tract(1)	4	Esophageal squamous(101;0.125)	Breast(259;0.134)			Aminophylline(DB01223)|Amrinone(DB01427)|Anagrelide(DB00261)|Cilostazol(DB01166)|Enoximone(DB04880)|Milrinone(DB00235)|Theophylline(DB00277)													---	---	---	---
SRGAP1	57522	broad.mit.edu	37	12	64265418	64265418	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:64265418delT	uc010ssp.1	+						SRGAP1_uc001srt.2_Intron	NM_020762	NP_065813			SLIT-ROBO Rho GTPase activating protein 1						axon guidance	cytosol				ovary(2)|central_nervous_system(2)	4			GBM - Glioblastoma multiforme(3;0.000139)|BRCA - Breast invasive adenocarcinoma(9;0.225)	GBM - Glioblastoma multiforme(28;0.0608)														---	---	---	---
SLC7A7	9056	broad.mit.edu	37	14	23244438	23244442	+	Intron	DEL	CTTAT	-	-	rs71421155		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr14:23244438_23244442delCTTAT	uc001wgr.3	-						SLC7A7_uc001wgs.3_Intron|SLC7A7_uc001wgt.3_Intron|SLC7A7_uc001wgu.3_Intron|SLC7A7_uc001wgv.3_Intron	NM_003982	NP_003973			solute carrier family 7 member 7						blood coagulation|cellular amino acid metabolic process|ion transport|leukocyte migration|protein complex assembly	basolateral plasma membrane|integral to plasma membrane	amino acid transmembrane transporter activity			ovary(1)|breast(1)	2	all_cancers(95;8.44e-05)			GBM - Glioblastoma multiforme(265;0.00741)														---	---	---	---
RAD51	5888	broad.mit.edu	37	15	40993575	40993575	+	Intron	DEL	T	-	-	rs67977099		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr15:40993575delT	uc001zmi.3	+						RAD51_uc010bbw.2_Intron|RAD51_uc010bbx.2_Intron|RAD51_uc001zmk.3_Intron|RAD51_uc001zml.3_Intron|RAD51_uc001zmm.1_Intron|RAD51_uc001zmn.1_Intron	NM_002875	NP_002866			RAD51 homolog protein isoform 1						DNA recombinase assembly|DNA unwinding involved in replication|mitotic recombination|positive regulation of DNA ligation|protein homooligomerization|reciprocal meiotic recombination	mitochondrial matrix|nucleus|perinuclear region of cytoplasm|PML body	ATP binding|damaged DNA binding|double-stranded DNA binding|identical protein binding|protein C-terminus binding|single-stranded DNA binding|single-stranded DNA-dependent ATPase activity				0		all_cancers(109;1.19e-18)|all_epithelial(112;2.33e-15)|Lung NSC(122;5.34e-11)|all_lung(180;1.33e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0822)|Colorectal(260;0.0946)		GBM - Glioblastoma multiforme(113;1.45e-05)|BRCA - Breast invasive adenocarcinoma(123;0.000421)|COAD - Colon adenocarcinoma(120;0.163)									Homologous_recombination					---	---	---	---
MCTP2	55784	broad.mit.edu	37	15	94842066	94842067	+	Intron	INS	-	CT	CT	rs149048088	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr15:94842066_94842067insCT	uc002btj.2	+						MCTP2_uc010urg.1_Intron|MCTP2_uc002bti.2_Intron|MCTP2_uc010boj.2_Intron|MCTP2_uc010bok.2_Intron|MCTP2_uc002btg.3_Intron|MCTP2_uc002bth.3_Intron	NM_018349	NP_060819			multiple C2 domains, transmembrane 2 isoform 1						calcium-mediated signaling	integral to membrane|membrane fraction	calcium ion binding			ovary(1)|pancreas(1)|skin(1)	3	Lung NSC(78;0.0821)|all_lung(78;0.148)		BRCA - Breast invasive adenocarcinoma(143;0.0323)|OV - Ovarian serous cystadenocarcinoma(32;0.0593)															---	---	---	---
LASS3	204219	broad.mit.edu	37	15	101019972	101019973	+	Intron	DEL	TG	-	-	rs34347308		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr15:101019972_101019973delTG	uc002bvz.2	-						LASS3_uc002bwa.2_Intron|LASS3_uc002bwb.2_Intron	NM_178842	NP_849164			LAG1 longevity assurance homolog 3							endoplasmic reticulum membrane|integral to membrane|nuclear membrane	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|sphingosine N-acyltransferase activity			ovary(2)|pancreas(1)|skin(1)	4	Lung NSC(78;0.0018)|all_lung(78;0.00278)|Melanoma(26;0.00852)		OV - Ovarian serous cystadenocarcinoma(32;0.000867)|LUSC - Lung squamous cell carcinoma(107;0.132)|Lung(145;0.161)															---	---	---	---
C16orf71	146562	broad.mit.edu	37	16	4788056	4788056	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr16:4788056delT	uc002cxn.2	+							NM_139170	NP_631909			hypothetical protein LOC146562											central_nervous_system(1)	1																		---	---	---	---
GDE1	51573	broad.mit.edu	37	16	19522426	19522426	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr16:19522426delT	uc002dgh.2	-						GDE1_uc002dgi.2_Intron	NM_016641	NP_057725			glycerophosphodiester phosphodiesterase 1						glycerol metabolic process|lipid metabolic process	cytoplasm|integral to membrane	glycerophosphodiester phosphodiesterase activity|glycerophosphoinositol glycerophosphodiesterase activity|metal ion binding			ovary(2)|central_nervous_system(1)	3																		---	---	---	---
UMOD	7369	broad.mit.edu	37	16	20352332	20352332	+	Intron	DEL	G	-	-	rs11642202		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr16:20352332delG	uc002dgz.2	-						UMOD_uc002dha.2_Intron|UMOD_uc002dhb.2_Intron	NM_003361	NP_003352			uromodulin precursor						cellular defense response|negative regulation of cell proliferation	anchored to membrane|apical plasma membrane|basolateral plasma membrane|cilium membrane|extrinsic to membrane|primary cilium|spindle pole	calcium ion binding			ovary(1)|skin(1)	2																		---	---	---	---
MAZ	4150	broad.mit.edu	37	16	29821005	29821006	+	Intron	INS	-	G	G			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr16:29821005_29821006insG	uc002dty.2	+						uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|MAZ_uc002dtv.1_Intron|MAZ_uc010vdx.1_Intron|MAZ_uc002dtw.2_Intron|MAZ_uc002dtx.2_Frame_Shift_Ins_p.L475fs|MAZ_uc010bzg.2_Intron|MAZ_uc002dtz.1_3'UTR|MAZ_uc002dua.2_Frame_Shift_Ins_p.L76fs|MAZ_uc010vdy.1_Intron|uc002duc.1_Intron|PRRT2_uc002dud.2_5'Flank|PRRT2_uc002due.3_5'Flank|PRRT2_uc002duf.1_5'Flank	NM_002383	NP_002374			MYC-associated zinc finger protein isoform 1						regulation of transcription, DNA-dependent|termination of RNA polymerase II transcription|transcription initiation from RNA polymerase II promoter	nucleus	DNA binding|protein binding|RNA binding|zinc ion binding			ovary(1)	1																		---	---	---	---
LRRC50	123872	broad.mit.edu	37	16	84183684	84183686	+	Intron	DEL	AAG	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr16:84183684_84183686delAAG	uc002fhl.3	+						LRRC50_uc010chi.1_Intron	NM_178452	NP_848547			leucine rich repeat containing 50						axonemal dynein complex assembly|cilium morphogenesis	cilium axoneme|cytoplasm|spindle pole	dynein binding				0														Kartagener_syndrome				---	---	---	---
PLD2	5338	broad.mit.edu	37	17	4725799	4725799	+	Intron	DEL	G	-	-	rs2875841		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:4725799delG	uc002fzc.2	+						PLD2_uc002fzd.2_Intron	NM_002663	NP_002654			phospholipase D2						cell communication|cytoskeleton organization|small GTPase mediated signal transduction		NAPE-specific phospholipase D activity|phosphatidylinositol binding|phospholipase D activity			breast(2)|upper_aerodigestive_tract(1)|ovary(1)|central_nervous_system(1)	5					Choline(DB00122)													---	---	---	---
ABCA5	23461	broad.mit.edu	37	17	67281850	67281850	+	Intron	DEL	A	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:67281850delA	uc002jif.2	-						ABCA5_uc002jic.2_Intron|ABCA5_uc002jid.2_Intron|ABCA5_uc002jie.2_Intron|ABCA5_uc002jig.2_Intron|ABCA5_uc002jih.2_Intron|ABCA5_uc010dfe.2_Intron	NM_018672	NP_061142			ATP-binding cassette, sub-family A , member 5						cholesterol efflux|high-density lipoprotein particle remodeling|negative regulation of macrophage derived foam cell differentiation	Golgi membrane|integral to membrane|late endosome membrane|lysosomal membrane	ATP binding|ATPase activity			ovary(2)|central_nervous_system(1)|skin(1)	4	Breast(10;3.72e-11)																	---	---	---	---
FN3K	64122	broad.mit.edu	37	17	80696192	80696193	+	Intron	INS	-	G	G	rs140281589	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:80696192_80696193insG	uc010wvs.1	+						FN3K_uc002kfw.1_5'UTR	NM_022158	NP_071441			fructosamine 3 kinase						fructoselysine metabolic process		fructosamine-3-kinase activity				0	Breast(20;0.000523)|all_neural(118;0.0952)		BRCA - Breast invasive adenocarcinoma(99;0.0344)|OV - Ovarian serous cystadenocarcinoma(97;0.061)															---	---	---	---
CARM1	10498	broad.mit.edu	37	19	11023195	11023195	+	Intron	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:11023195delT	uc002mpz.2	+						CARM1_uc010dxn.2_Intron|CARM1_uc002mqa.2_Intron	NM_199141	NP_954592			coactivator-associated arginine						cellular lipid metabolic process|histone H3-R2 methylation|interspecies interaction between organisms|pathogenesis|positive regulation of fat cell differentiation|regulation of estrogen receptor signaling pathway|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|nucleoplasm	beta-catenin binding|histone acetyl-lysine binding|histone methyltransferase activity (H3-R17 specific)|ligand-dependent nuclear receptor transcription coactivator activity|protein-arginine omega-N asymmetric methyltransferase activity|transcription regulatory region DNA binding				0																		---	---	---	---
C19orf44	84167	broad.mit.edu	37	19	16625243	16625243	+	Intron	DEL	G	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:16625243delG	uc002neh.1	+						MED26_uc002nee.2_Intron|C19orf44_uc002neg.2_Intron|C19orf44_uc010eai.1_Intron	NM_032207	NP_115583			hypothetical protein LOC84167												0																		---	---	---	---
TEAD2	8463	broad.mit.edu	37	19	49845484	49845485	+	Intron	INS	-	CCACATCAGTT	CCACATCAGTT	rs149352076	by1000genomes	TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:49845484_49845485insCCACATCAGTT	uc002pnj.2	-						uc002pnb.1_5'Flank|TEAD2_uc002png.2_Intron|TEAD2_uc002pnh.2_Intron|TEAD2_uc002pni.2_Intron|TEAD2_uc010yao.1_Intron|TEAD2_uc010emw.2_Intron	NM_003598	NP_003589			TEA domain family member 2						hippo signaling cascade		DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			central_nervous_system(2)|ovary(1)	3		all_lung(116;7.65e-05)|Lung NSC(112;0.000132)|all_neural(266;0.0506)|Ovarian(192;0.15)		OV - Ovarian serous cystadenocarcinoma(262;0.00093)|GBM - Glioblastoma multiforme(486;0.0467)														---	---	---	---
ZNF543	125919	broad.mit.edu	37	19	57840883	57840883	+	3'UTR	DEL	T	-	-	rs35786977		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:57840883delT	uc002qoi.1	+	4						NM_213598	NP_998763			zinc finger protein 543						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			skin(1)|pancreas(1)	2		Colorectal(82;0.000256)|all_neural(62;0.0577)|Ovarian(87;0.221)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0257)														---	---	---	---
ARFRP1	10139	broad.mit.edu	37	20	62333351	62333354	+	Intron	DEL	CCCC	-	-	rs66479347		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr20:62333351_62333354delCCCC	uc002yga.2	-						ARFRP1_uc002ygc.2_Intron|ARFRP1_uc002ygh.3_Intron|ARFRP1_uc011abf.1_Intron|ARFRP1_uc011abg.1_Intron|ARFRP1_uc002yge.2_Intron|ARFRP1_uc002ygd.2_Intron|ARFRP1_uc002ygf.2_Intron|ARFRP1_uc002ygg.2_Intron|ARFRP1_uc011abh.1_Intron	NM_003224	NP_003215			ADP-ribosylation factor related protein 1						small GTPase mediated signal transduction	Golgi apparatus|membrane fraction	GTP binding|GTPase activity			breast(1)|skin(1)	2	all_cancers(38;9.53e-13)|all_epithelial(29;2.64e-14)|Lung NSC(23;7e-10)|all_lung(23;2.53e-09)		Epithelial(9;4.09e-08)|all cancers(9;1.7e-07)|OV - Ovarian serous cystadenocarcinoma(5;0.0102)															---	---	---	---
CXADR	1525	broad.mit.edu	37	21	18931675	18931675	+	Intron	DEL	A	-	-	rs147134822		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr21:18931675delA	uc002yki.2	+						CXADR_uc002ykh.1_Intron|CXADR_uc010gld.1_Intron|CXADR_uc010gle.1_Intron|CXADR_uc002ykj.1_Intron	NM_001338	NP_001329			coxsackie virus and adenovirus receptor						blood coagulation|cell adhesion|interspecies interaction between organisms|leukocyte migration|regulation of immune response	adherens junction|basolateral plasma membrane|extracellular region|integral to plasma membrane|nucleus|tight junction	receptor activity			ovary(1)	1				Epithelial(23;0.000206)|all cancers(11;0.000302)|OV - Ovarian serous cystadenocarcinoma(11;0.0194)|Lung(58;0.0233)|COAD - Colon adenocarcinoma(22;0.0389)|Colorectal(24;0.0483)|LUSC - Lung squamous cell carcinoma(23;0.0782)														---	---	---	---
Unknown	0	broad.mit.edu	37	21	44756755	44756755	+	IGR	DEL	A	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr21:44756755delA								CRYAA (163842 upstream) : SIK1 (77643 downstream)																																			---	---	---	---
DGCR5	26220	broad.mit.edu	37	22	18976301	18976308	+	Intron	DEL	TATTTATT	-	-	rs111433751		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr22:18976301_18976308delTATTTATT	uc002zom.1	+						DGCR5_uc002zon.1_Intron	NR_002733				Homo sapiens mRNA for KIAA1647 protein, partial cds.												0																		---	---	---	---
IL3RA	3563	broad.mit.edu	37	X	1501564	1501564	+	3'UTR	DEL	T	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chrX:1501564delT	uc004cps.2	+	12					IL3RA_uc011mhd.1_3'UTR	NM_002183	NP_002174			interleukin 3 receptor, alpha precursor							integral to membrane|plasma membrane	interleukin-3 receptor activity			skin(2)|lung(1)	3		all_cancers(21;4.28e-07)|all_epithelial(21;2.07e-08)|all_lung(23;2.81e-05)|Lung NSC(23;0.000693)|Lung SC(21;0.122)			Sargramostim(DB00020)													---	---	---	---
STARD8	9754	broad.mit.edu	37	X	67936366	67936369	+	Intron	DEL	CCCA	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chrX:67936366_67936369delCCCA	uc004dxa.2	+						STARD8_uc004dxb.2_Intron|STARD8_uc004dxc.3_Intron	NM_014725	NP_055540			StAR-related lipid transfer (START) domain						regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytosol|focal adhesion	GTPase activator activity			breast(3)|ovary(2)|pancreas(1)	6																		---	---	---	---
DOCK11	139818	broad.mit.edu	37	X	117676483	117676484	+	Intron	INS	-	TA	TA	rs149027952		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chrX:117676483_117676484insTA	uc004eqp.2	+							NM_144658	NP_653259			dedicator of cytokinesis 11						blood coagulation	cytosol	GTP binding			ovary(3)	3																		---	---	---	---
Unknown	0	broad.mit.edu	37	X	123353666	123353669	+	IGR	DEL	CTTC	-	-			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chrX:123353666_123353669delCTTC								STAG2 (117163 upstream) : SH2D1A (126479 downstream)																																			---	---	---	---
NEXN	91624	broad.mit.edu	37	1	78395101	78395101	+	Missense_Mutation	SNP	G	C	C			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:78395101G>C	uc001dic.3	+	9	1262	c.965G>C	c.(964-966)AGA>ACA	p.R322T	NEXN_uc001dia.3_Missense_Mutation_p.R308T|NEXN_uc009wcb.1_Missense_Mutation_p.R244T|NEXN_uc001dib.3_Missense_Mutation_p.R258T|NEXN_uc001did.1_Missense_Mutation_p.R232T|NEXN_uc001dif.1_Missense_Mutation_p.R214T	NM_144573	NP_653174	Q0ZGT2	NEXN_HUMAN	nexilin (F actin binding protein)	322	Glu-rich.				regulation of cell migration|regulation of cytoskeleton organization	cytoskeleton|Z disc	actin filament binding|structural constituent of muscle			ovary(2)	2				Colorectal(170;0.114)														---	---	---	---
COL24A1	255631	broad.mit.edu	37	1	86591541	86591541	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:86591541C>T	uc001dlj.2	-	3	520	c.478G>A	c.(478-480)GAT>AAT	p.D160N	COL24A1_uc010osd.1_5'UTR|COL24A1_uc001dlk.2_RNA|COL24A1_uc010ose.1_RNA|COL24A1_uc010osf.1_RNA|COL24A1_uc009wcq.2_Missense_Mutation_p.D160N	NM_152890	NP_690850	Q17RW2	COOA1_HUMAN	collagen, type XXIV, alpha 1 precursor	160	TSP N-terminal.|Laminin G-like.				cell adhesion	collagen	extracellular matrix structural constituent			ovary(3)|central_nervous_system(1)|skin(1)	5				all cancers(265;0.0627)|Epithelial(280;0.0689)														---	---	---	---
BPNT1	10380	broad.mit.edu	37	1	220242771	220242771	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:220242771C>T	uc001hma.2	-	5	509	c.337G>A	c.(337-339)GTG>ATG	p.V113M	BPNT1_uc010pug.1_Missense_Mutation_p.V58M|BPNT1_uc010puh.1_Missense_Mutation_p.V77M|BPNT1_uc001hmb.3_Missense_Mutation_p.V113M	NM_006085	NP_006076	O95861	BPNT1_HUMAN	3'(2'), 5'-bisphosphate nucleotidase 1	113					3'-phosphoadenosine 5'-phosphosulfate metabolic process|nervous system development|xenobiotic metabolic process	cytosol	3'(2'),5'-bisphosphate nucleotidase activity			ovary(1)	1				GBM - Glioblastoma multiforme(131;0.0558)														---	---	---	---
KCNF1	3754	broad.mit.edu	37	2	11053370	11053370	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:11053370C>T	uc002rax.2	+	1	1308	c.818C>T	c.(817-819)ACG>ATG	p.T273M		NM_002236	NP_002227	Q9H3M0	KCNF1_HUMAN	potassium voltage-gated channel, subfamily F,	273						voltage-gated potassium channel complex	voltage-gated potassium channel activity			ovary(1)	1	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.191)			Epithelial(75;0.115)|OV - Ovarian serous cystadenocarcinoma(76;0.128)														---	---	---	---
GDF7	151449	broad.mit.edu	37	2	20871059	20871059	+	Silent	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:20871059G>A	uc002rdz.1	+	2	1803	c.1227G>A	c.(1225-1227)GCG>GCA	p.A409A		NM_182828	NP_878248	Q7Z4P5	GDF7_HUMAN	growth differentiation factor 7 preproprotein	409					activin receptor signaling pathway|BMP signaling pathway|growth|pathway-restricted SMAD protein phosphorylation|positive regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of transcription, DNA-dependent	extracellular space	cytokine activity|growth factor activity				0	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)																	---	---	---	---
TCF23	150921	broad.mit.edu	37	2	27373194	27373194	+	Silent	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:27373194G>A	uc010ylg.1	+	2	426	c.426G>A	c.(424-426)CCG>CCA	p.P142P		NM_175769	NP_786951	Q7RTU1	TCF23_HUMAN	transcription factor 23	142					cell differentiation|muscle organ development|regulation of transcription, DNA-dependent	nucleus					0	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)																	---	---	---	---
GPR39	2863	broad.mit.edu	37	2	133175294	133175294	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:133175294G>A	uc002ttl.2	+	1	1148	c.679G>A	c.(679-681)GCC>ACC	p.A227T		NM_001508	NP_001499	O43194	GPR39_HUMAN	G protein-coupled receptor 39	227	Helical; Name=5; (Potential).					integral to plasma membrane	G-protein coupled receptor activity|metal ion binding				0																		---	---	---	---
TNS1	7145	broad.mit.edu	37	2	218683433	218683433	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:218683433G>A	uc002vgt.2	-	24	3708	c.3310C>T	c.(3310-3312)CGG>TGG	p.R1104W	TNS1_uc002vgr.2_Missense_Mutation_p.R1091W|TNS1_uc002vgs.2_Missense_Mutation_p.R1083W|TNS1_uc010zjv.1_Missense_Mutation_p.R1083W	NM_022648	NP_072174	Q9HBL0	TENS1_HUMAN	tensin	1104	Ser-rich.					cytoplasm|cytoskeleton|focal adhesion	actin binding			ovary(3)|breast(1)	4		Renal(207;0.0483)|Lung NSC(271;0.213)		Epithelial(149;4.43e-06)|all cancers(144;0.000653)|LUSC - Lung squamous cell carcinoma(224;0.0091)|Lung(261;0.013)														---	---	---	---
KCNH8	131096	broad.mit.edu	37	3	19384207	19384207	+	Splice_Site	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:19384207G>A	uc003cbk.1	+	4	765	c.570_splice	c.e4+1	p.N190_splice	KCNH8_uc011awe.1_Splice_Site_p.N190_splice|KCNH8_uc010hex.1_Splice_Site	NM_144633	NP_653234			potassium voltage-gated channel, subfamily H,							integral to membrane	two-component sensor activity			lung(4)|ovary(1)	5																		---	---	---	---
C3orf72	401089	broad.mit.edu	37	3	138669287	138669287	+	Missense_Mutation	SNP	G	C	C			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:138669287G>C	uc003esx.1	+	3	532	c.401G>C	c.(400-402)GGA>GCA	p.G134A	C3orf72_uc011bmr.1_3'UTR	NM_001040061	NP_001035150	Q6ZUU3	CC072_HUMAN	chromosome 3 open reading frame 72	134											0																		---	---	---	---
GHSR	2693	broad.mit.edu	37	3	172165669	172165669	+	Missense_Mutation	SNP	A	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:172165669A>T	uc003fib.1	-	1	535	c.535T>A	c.(535-537)TTC>ATC	p.F179I	GHSR_uc011bpv.1_Missense_Mutation_p.F179I	NM_198407	NP_940799	Q92847	GHSR_HUMAN	growth hormone secretagogue receptor isoform 1a	179	Helical; Name=4; (Potential).				actin polymerization or depolymerization|adult feeding behavior|decidualization|growth hormone secretion|hormone-mediated signaling pathway|negative regulation of inflammatory response|negative regulation of interleukin-1 beta production|negative regulation of interleukin-6 biosynthetic process|negative regulation of tumor necrosis factor biosynthetic process|positive regulation of appetite|positive regulation of multicellular organism growth	cell surface|integral to membrane|membrane raft|neuron projection|plasma membrane	growth hormone secretagogue receptor activity|growth hormone-releasing hormone receptor activity			lung(3)|ovary(1)|central_nervous_system(1)	5	Ovarian(172;0.00143)|Breast(254;0.197)		Lung(28;3.93e-15)|LUSC - Lung squamous cell carcinoma(14;1.48e-14)|STAD - Stomach adenocarcinoma(35;0.235)															---	---	---	---
TBCCD1	55171	broad.mit.edu	37	3	186272346	186272346	+	Missense_Mutation	SNP	A	G	G			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:186272346A>G	uc003fqg.2	-	6	1370	c.1241T>C	c.(1240-1242)GTA>GCA	p.V414A	TBCCD1_uc011bry.1_Missense_Mutation_p.V414A|TBCCD1_uc003fqh.2_Missense_Mutation_p.V318A	NM_018138	NP_060608	Q9NVR7	TBCC1_HUMAN	TBCC domain containing 1	414	C-CAP/cofactor C-like.				cell morphogenesis|maintenance of centrosome location|maintenance of Golgi location|regulation of cell migration|regulation of cell shape	spindle pole centrosome	binding			large_intestine(1)|ovary(1)	2	all_cancers(143;3.75e-12)|Ovarian(172;0.0339)		OV - Ovarian serous cystadenocarcinoma(80;4.3e-21)	GBM - Glioblastoma multiforme(93;0.0474)														---	---	---	---
RFC4	5984	broad.mit.edu	37	3	186509621	186509621	+	Missense_Mutation	SNP	T	C	C			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:186509621T>C	uc003fqz.2	-	8	917	c.694A>G	c.(694-696)AAA>GAA	p.K232E	RFC4_uc011bsc.1_Missense_Mutation_p.K232E|RFC4_uc011bsd.1_Missense_Mutation_p.K232E	NM_002916	NP_002907	P35249	RFC4_HUMAN	replication factor C 4	232					cell cycle checkpoint|DNA strand elongation involved in DNA replication|nucleotide-excision repair, DNA gap filling|phosphatidylinositol-mediated signaling|S phase of mitotic cell cycle|telomere maintenance via recombination|telomere maintenance via semi-conservative replication|transcription-coupled nucleotide-excision repair	DNA replication factor C complex|nucleoplasm	ATP binding|DNA clamp loader activity|protein binding			breast(2)|upper_aerodigestive_tract(1)|ovary(1)|large_intestine(1)	5	all_cancers(143;2.92e-12)|Ovarian(172;0.0339)		OV - Ovarian serous cystadenocarcinoma(80;7.41e-21)	GBM - Glioblastoma multiforme(93;0.0739)														---	---	---	---
C4orf50	389197	broad.mit.edu	37	4	5969171	5969171	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr4:5969171C>T	uc003git.1	-	5	517	c.427G>A	c.(427-429)GTC>ATC	p.V143I		NM_207405	NP_997288	Q6ZRC1	CD050_HUMAN	hypothetical protein LOC389197	143										pancreas(2)|breast(1)	3																		---	---	---	---
ASB5	140458	broad.mit.edu	37	4	177142387	177142387	+	Nonsense_Mutation	SNP	C	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr4:177142387C>A	uc003iuq.1	-	5	605	c.589G>T	c.(589-591)GAA>TAA	p.E197*	ASB5_uc003iup.1_Nonsense_Mutation_p.E144*	NM_080874	NP_543150	Q8WWX0	ASB5_HUMAN	ankyrin repeat and SOCS box-containing protein	197					intracellular signal transduction					skin(2)	2		Breast(14;0.00015)|Melanoma(52;0.00886)|Prostate(90;0.00996)|Renal(120;0.0183)|all_hematologic(60;0.107)|all_neural(102;0.164)		all cancers(43;2.13e-20)|Epithelial(43;9.94e-18)|OV - Ovarian serous cystadenocarcinoma(60;2e-09)|GBM - Glioblastoma multiforme(59;0.000254)|STAD - Stomach adenocarcinoma(60;0.000653)|LUSC - Lung squamous cell carcinoma(193;0.0393)														---	---	---	---
KIAA0947	23379	broad.mit.edu	37	5	5463022	5463022	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr5:5463022C>T	uc003jdm.3	+	13	3797	c.3575C>T	c.(3574-3576)TCT>TTT	p.S1192F		NM_015325	NP_056140	Q9Y2F5	K0947_HUMAN	hypothetical protein LOC23379	1192										ovary(1)|central_nervous_system(1)	2																		---	---	---	---
ENC1	8507	broad.mit.edu	37	5	73931260	73931260	+	Missense_Mutation	SNP	C	G	G	rs144525141		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr5:73931260C>G	uc003kdc.3	-	2	2182	c.1051G>C	c.(1051-1053)GAA>CAA	p.E351Q	ENC1_uc011css.1_Missense_Mutation_p.E278Q	NM_003633	NP_003624	O14682	ENC1_HUMAN	ectodermal-neural cortex (with BTB-like domain)	351	Kelch 2.				nervous system development	cytoplasm|cytoskeleton|nuclear matrix	actin binding			ovary(1)|pancreas(1)|skin(1)	3		all_lung(232;0.0154)|Lung NSC(167;0.0331)|Ovarian(174;0.0798)		OV - Ovarian serous cystadenocarcinoma(47;1.45e-59)														---	---	---	---
F12	2161	broad.mit.edu	37	5	176832124	176832124	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr5:176832124C>T	uc003mgo.3	-	6	509	c.460G>A	c.(460-462)GAG>AAG	p.E154K	F12_uc011dfy.1_5'Flank|F12_uc003mgn.3_5'Flank|F12_uc010jkl.2_RNA	NM_000505	NP_000496	P00748	FA12_HUMAN	coagulation factor XII precursor	154	Fibronectin type-I.				Factor XII activation|fibrinolysis|innate immune response|positive regulation of blood coagulation|positive regulation of fibrinolysis|positive regulation of plasminogen activation|protein autoprocessing|response to misfolded protein|zymogen activation	extracellular space|plasma membrane	serine-type endopeptidase activity				0	all_cancers(89;2.04e-05)|Renal(175;0.000269)|Lung NSC(126;0.000832)|all_lung(126;0.00152)	all_neural(177;0.00409)|Medulloblastoma(196;0.00498)|all_hematologic(541;0.21)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)											Hereditary_Angioedema				---	---	---	---
HIST1H1E	3008	broad.mit.edu	37	6	26156976	26156976	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:26156976G>A	uc003ngq.2	+	1	418	c.358G>A	c.(358-360)GCT>ACT	p.A120T	HIST1H2BD_uc003ngr.2_5'Flank|HIST1H2BD_uc003ngs.2_5'Flank	NM_005321	NP_005312	P10412	H14_HUMAN	histone cluster 1, H1e	120					nucleosome assembly	nucleosome|nucleus	DNA binding|protein binding			large_intestine(1)|ovary(1)	2																		---	---	---	---
ZNF187	7741	broad.mit.edu	37	6	28240525	28240525	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:28240525C>T	uc011dld.1	+	4	766	c.496C>T	c.(496-498)CGG>TGG	p.R166W	ZNF187_uc011dlc.1_Missense_Mutation_p.R167W|ZNF187_uc003nku.3_Missense_Mutation_p.R32W|ZNF187_uc003nkw.3_Missense_Mutation_p.R13W|ZNF187_uc011dle.1_Missense_Mutation_p.R13W|ZNF187_uc011dlf.1_Intron|ZNF187_uc011dlg.1_Missense_Mutation_p.R13W	NM_001111039	NP_001104509	Q16670	ZN187_HUMAN	zinc finger protein 187 isoform b	166					viral reproduction	nucleus	nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding				0																		---	---	---	---
ZFP57	346171	broad.mit.edu	37	6	29643828	29643828	+	Silent	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:29643828G>A	uc011dlw.1	-	2	283	c.132C>T	c.(130-132)GTC>GTT	p.V44V	ZFP57_uc003nnl.3_Silent_p.V24V	NM_001109809	NP_001103279	Q9NU63	ZFP57_HUMAN	zinc finger protein 57 homolog	16	KRAB.				DNA methylation involved in embryo development|regulation of gene expression by genetic imprinting|transcription, DNA-dependent		DNA binding|zinc ion binding			ovary(3)|skin(2)	5																		---	---	---	---
RING1	6015	broad.mit.edu	37	6	33177736	33177736	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:33177736G>A	uc003odk.2	+	4	478	c.284G>A	c.(283-285)CGA>CAA	p.R95Q	RING1_uc011dqx.1_Missense_Mutation_p.R95Q|RING1_uc003odl.2_Missense_Mutation_p.R66Q	NM_002931	NP_002922	Q06587	RING1_HUMAN	ring finger protein 1	95	Necessary for transcriptional repression (By similarity).				histone H2A monoubiquitination|negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nuclear speck|PcG protein complex	protein binding|zinc ion binding			ovary(1)|skin(1)	2																		---	---	---	---
SMOC2	64094	broad.mit.edu	37	6	168910683	168910683	+	Missense_Mutation	SNP	G	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:168910683G>T	uc003qws.1	+	2	193	c.173G>T	c.(172-174)AGG>ATG	p.R58M	SMOC2_uc003qwr.1_Missense_Mutation_p.R58M	NM_022138	NP_071421	Q9H3U7	SMOC2_HUMAN	SPARC related modular calcium binding 2	58	Kazal-like.				signal transduction	basement membrane	calcium ion binding			ovary(1)	1		Breast(66;0.000141)|Esophageal squamous(34;0.222)|Ovarian(120;0.231)		OV - Ovarian serous cystadenocarcinoma(33;1.31e-19)|BRCA - Breast invasive adenocarcinoma(81;3.06e-06)|GBM - Glioblastoma multiforme(31;0.00109)														---	---	---	---
RNF216	54476	broad.mit.edu	37	7	5781105	5781105	+	Missense_Mutation	SNP	C	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:5781105C>A	uc003soy.1	-	4	562	c.372G>T	c.(370-372)TTG>TTT	p.L124F	RNF216_uc010ksz.1_5'UTR|RNF216_uc010kta.1_Intron|RNF216_uc011jwj.1_Intron|RNF216_uc003sox.1_Missense_Mutation_p.L181F	NM_207116	NP_996999	Q9NWF9	RN216_HUMAN	ring finger protein 216 isoform b	124					apoptosis|interspecies interaction between organisms|proteasomal ubiquitin-dependent protein catabolic process|protein K48-linked ubiquitination|regulation of defense response to virus by host|regulation of interferon-beta production	cytoplasm|nucleus|nucleus	ligase activity|protein binding|protein binding|zinc ion binding			ovary(3)|breast(2)	5		Ovarian(82;0.07)		UCEC - Uterine corpus endometrioid carcinoma (126;0.135)|OV - Ovarian serous cystadenocarcinoma(56;2.69e-13)														---	---	---	---
CREB5	9586	broad.mit.edu	37	7	28844124	28844124	+	Silent	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:28844124C>T	uc003szq.2	+	8	1401	c.1011C>T	c.(1009-1011)ACC>ACT	p.T337T	CREB5_uc003szo.2_Silent_p.T304T|CREB5_uc003szr.2_Silent_p.T330T|CREB5_uc003szs.2_Silent_p.T198T	NM_182898	NP_878901	Q02930	CREB5_HUMAN	cAMP responsive element binding protein 5	337					positive regulation of transcription, DNA-dependent|transcription from RNA polymerase II promoter		protein dimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			skin(2)	2																		---	---	---	---
ESCO2	157570	broad.mit.edu	37	8	27660907	27660907	+	Silent	SNP	C	G	G			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr8:27660907C>G	uc003xgg.2	+	11	1841	c.1758C>G	c.(1756-1758)ACC>ACG	p.T586T	ESCO2_uc010luy.1_Intron	NM_001017420	NP_001017420	Q56NI9	ESCO2_HUMAN	establishment of cohesion 1 homolog 2	586					cell cycle|post-translational protein acetylation|regulation of DNA replication	chromatin|nucleus	acyltransferase activity|metal ion binding			central_nervous_system(1)	1		Ovarian(32;0.000953)		UCEC - Uterine corpus endometrioid carcinoma (27;0.0204)|KIRC - Kidney renal clear cell carcinoma(542;0.0955)|Kidney(114;0.115)|Colorectal(74;0.132)										SC_Phocomelia_syndrome				---	---	---	---
C8orf41	80185	broad.mit.edu	37	8	33371030	33371030	+	5'Flank	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr8:33371030C>T	uc003xjl.3	-						C8orf41_uc003xjk.3_5'Flank|C8orf41_uc010lvv.2_5'Flank|C8orf41_uc003xjm.3_5'Flank|C8orf41_uc003xjn.1_5'Flank	NM_025115	NP_079391			hypothetical protein LOC80185								binding				0				KIRC - Kidney renal clear cell carcinoma(67;0.0923)|Kidney(114;0.111)														---	---	---	---
SULF1	23213	broad.mit.edu	37	8	70536309	70536309	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr8:70536309G>A	uc010lza.1	+	15	2444	c.1727G>A	c.(1726-1728)CGT>CAT	p.R576H	SULF1_uc003xyd.2_Missense_Mutation_p.R576H|SULF1_uc003xye.2_Missense_Mutation_p.R576H|SULF1_uc003xyf.2_Missense_Mutation_p.R576H|SULF1_uc003xyg.2_Missense_Mutation_p.R576H|SULF1_uc003xyh.1_RNA	NM_015170	NP_055985	Q8IWU6	SULF1_HUMAN	sulfatase 1 precursor	576					apoptosis|bone development|heparan sulfate proteoglycan metabolic process|kidney development|negative regulation of fibroblast growth factor receptor signaling pathway	cell surface|endoplasmic reticulum|extracellular space|Golgi stack	arylsulfatase activity|calcium ion binding			central_nervous_system(3)|ovary(2)|pancreas(1)|skin(1)	7	Breast(64;0.0654)		Epithelial(68;0.0124)|OV - Ovarian serous cystadenocarcinoma(28;0.0265)|all cancers(69;0.0534)															---	---	---	---
FREM1	158326	broad.mit.edu	37	9	14748594	14748594	+	Silent	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:14748594G>A	uc003zlm.2	-	31	6191	c.5601C>T	c.(5599-5601)AGC>AGT	p.S1867S	FREM1_uc010mic.2_RNA|FREM1_uc003zlk.2_Intron|FREM1_uc003zll.2_Silent_p.S403S	NM_144966	NP_659403	Q5H8C1	FREM1_HUMAN	FRAS1 related extracellular matrix 1 precursor	1867					cell communication|multicellular organismal development	basement membrane|integral to membrane	metal ion binding|sugar binding			ovary(2)|breast(2)|pancreas(1)	5				GBM - Glioblastoma multiforme(50;3.53e-06)														---	---	---	---
C9orf131	138724	broad.mit.edu	37	9	35045805	35045805	+	Missense_Mutation	SNP	A	G	G			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:35045805A>G	uc003zvw.2	+	2	3208	c.3179A>G	c.(3178-3180)CAA>CGA	p.Q1060R	C9orf131_uc003zvu.2_Missense_Mutation_p.Q1012R|C9orf131_uc003zvv.2_Missense_Mutation_p.Q987R|C9orf131_uc003zvx.2_Missense_Mutation_p.Q1025R	NM_203299	NP_976044	Q5VYM1	CI131_HUMAN	hypothetical protein LOC138724 isoform A	1060											0	all_epithelial(49;0.22)		LUSC - Lung squamous cell carcinoma(32;0.00117)|Lung(28;0.00309)															---	---	---	---
DAPK1	1612	broad.mit.edu	37	9	90321137	90321137	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:90321137G>A	uc004apc.2	+	26	3289	c.3151G>A	c.(3151-3153)GTG>ATG	p.V1051M	DAPK1_uc004apd.2_Missense_Mutation_p.V1051M|DAPK1_uc011ltg.1_Missense_Mutation_p.V985M|DAPK1_uc011lth.1_Missense_Mutation_p.V788M|DAPK1_uc004apg.2_Missense_Mutation_p.V28M	NM_004938	NP_004929	P53355	DAPK1_HUMAN	death-associated protein kinase 1	1051					apoptosis|induction of apoptosis by extracellular signals|intracellular protein kinase cascade	actin cytoskeleton|cytoplasm	ATP binding|calmodulin binding|protein serine/threonine kinase activity			ovary(1)|breast(1)	2														Chronic_Lymphocytic_Leukemia_Familial_Clustering_of				---	---	---	---
USP54	159195	broad.mit.edu	37	10	75258563	75258563	+	Nonsense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr10:75258563G>A	uc001juo.2	-	22	4896	c.4879C>T	c.(4879-4881)CGA>TGA	p.R1627*	PPP3CB_uc001juf.2_5'Flank|PPP3CB_uc001jue.2_5'Flank|PPP3CB_uc001jug.2_5'Flank|PPP3CB_uc001jui.2_5'Flank|PPP3CB_uc001juh.2_5'Flank|USP54_uc010qkk.1_Nonsense_Mutation_p.R762*|USP54_uc001juk.2_Nonsense_Mutation_p.R715*|USP54_uc001jul.2_Nonsense_Mutation_p.R668*|USP54_uc001jum.2_RNA|USP54_uc001jun.2_RNA	NM_152586	NP_689799	Q70EL1	UBP54_HUMAN	ubiquitin specific peptidase 54	1627					ubiquitin-dependent protein catabolic process		protein binding|ubiquitin thiolesterase activity			breast(3)|lung(2)|kidney(1)	6	Prostate(51;0.0112)																	---	---	---	---
PRR5L	79899	broad.mit.edu	37	11	36484155	36484155	+	Missense_Mutation	SNP	C	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr11:36484155C>A	uc001mwo.3	+	9	1365	c.976C>A	c.(976-978)CCA>ACA	p.P326T	PRR5L_uc001mwp.2_Missense_Mutation_p.P326T|PRR5L_uc009ykk.2_Missense_Mutation_p.P198T|PRR5L_uc010rfc.1_3'UTR	NM_001160167	NP_001153639	Q6MZQ0	PRR5L_HUMAN	protor-2 isoform a	326										ovary(1)	1																		---	---	---	---
ARFGAP2	84364	broad.mit.edu	37	11	47196833	47196833	+	Missense_Mutation	SNP	G	C	C			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr11:47196833G>C	uc001ndt.2	-	4	311	c.296C>G	c.(295-297)GCC>GGC	p.A99G	ARFGAP2_uc010rha.1_5'Flank|ARFGAP2_uc010rhb.1_Missense_Mutation_p.A99G|ARFGAP2_uc001ndu.2_Intron|ARFGAP2_uc010rhc.1_Intron|ARFGAP2_uc010rhd.1_Missense_Mutation_p.A99G|ARFGAP2_uc001ndv.1_3'UTR	NM_032389	NP_115765	Q8N6H7	ARFG2_HUMAN	ADP-ribosylation factor GTPase activating	99	Required for interaction with coatomer.|Arf-GAP.				protein transport|regulation of ARF GTPase activity|vesicle-mediated transport	Golgi membrane|nucleolus|plasma membrane	ARF GTPase activator activity|zinc ion binding			ovary(1)	1																		---	---	---	---
MS4A14	84689	broad.mit.edu	37	11	60183690	60183690	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr11:60183690C>T	uc001npj.2	+	5	1814	c.1249C>T	c.(1249-1251)CCT>TCT	p.P417S	MS4A14_uc001npi.2_Missense_Mutation_p.P305S|MS4A14_uc001npn.2_Missense_Mutation_p.P155S|MS4A14_uc001npk.2_Missense_Mutation_p.P400S|MS4A14_uc001npl.2_Missense_Mutation_p.P155S|MS4A14_uc001npm.2_Missense_Mutation_p.P155S	NM_032597	NP_115986	Q96JA4	M4A14_HUMAN	membrane-spanning 4-domains, subfamily A, member	417						integral to membrane	receptor activity			breast(1)	1																		---	---	---	---
FIBP	9158	broad.mit.edu	37	11	65655421	65655421	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr11:65655421C>T	uc001ogd.2	-	2	389	c.268G>A	c.(268-270)GCA>ACA	p.A90T	FIBP_uc009yqu.2_Missense_Mutation_p.A87T|FIBP_uc001oge.2_Missense_Mutation_p.A90T|FIBP_uc010roq.1_Missense_Mutation_p.A90T|FIBP_uc010ror.1_Missense_Mutation_p.A90T|CCDC85B_uc001ogf.2_5'Flank	NM_198897	NP_942600	O43427	FIBP_HUMAN	FGF intracellular binding protein isoform a	90					fibroblast growth factor receptor signaling pathway	endomembrane system|membrane|microsome|mitochondrion|nucleus	fibroblast growth factor binding			ovary(1)	1				READ - Rectum adenocarcinoma(159;0.166)														---	---	---	---
WNK1	65125	broad.mit.edu	37	12	1005298	1005298	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:1005298C>T	uc001qio.3	+	24	6152	c.5645C>T	c.(5644-5646)TCT>TTT	p.S1882F	WNK1_uc001qip.3_Missense_Mutation_p.S1634F|WNK1_uc001qir.3_Missense_Mutation_p.S1055F	NM_018979	NP_061852	Q9H4A3	WNK1_HUMAN	WNK lysine deficient protein kinase 1	1882					intracellular protein kinase cascade|ion transport|neuron development	cytoplasm	ATP binding|protein binding|protein kinase inhibitor activity|protein serine/threonine kinase activity			stomach(6)|breast(6)|ovary(5)|lung(4)|large_intestine(1)|central_nervous_system(1)	23	all_cancers(10;0.00611)|all_epithelial(11;0.00825)|all_lung(10;0.0331)|Ovarian(42;0.0512)|Lung NSC(10;0.0632)		Epithelial(1;1.74e-08)|all cancers(1;7.04e-08)|OV - Ovarian serous cystadenocarcinoma(31;0.000423)|BRCA - Breast invasive adenocarcinoma(9;0.0149)|Colorectal(1;0.0197)															---	---	---	---
GALNT8	26290	broad.mit.edu	37	12	4853826	4853826	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:4853826G>A	uc001qne.1	+	4	912	c.820G>A	c.(820-822)GTC>ATC	p.V274I		NM_017417	NP_059113	Q9NY28	GALT8_HUMAN	polypeptide N-acetylgalactosaminyltransferase 8	274	Lumenal (Potential).|Catalytic subdomain A.					Golgi membrane|integral to membrane	polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			ovary(2)|pancreas(1)|skin(1)	4																		---	---	---	---
GSG1	83445	broad.mit.edu	37	12	13241798	13241798	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:13241798C>T	uc001rbn.2	-	4	652	c.479G>A	c.(478-480)AGA>AAA	p.R160K	GSG1_uc001rbj.2_Missense_Mutation_p.R124K|GSG1_uc001rbk.2_Missense_Mutation_p.R124K|GSG1_uc001rbl.2_Missense_Mutation_p.R147K|GSG1_uc001rbm.2_Missense_Mutation_p.R124K|GSG1_uc001rbo.2_Missense_Mutation_p.R160K|GSG1_uc001rbp.2_Missense_Mutation_p.R137K|GSG1_uc001rbq.1_Missense_Mutation_p.R160K	NM_001080555	NP_001074024	Q2KHT4	GSG1_HUMAN	germ cell associated 1 isoform 4	147						endoplasmic reticulum membrane|integral to membrane					0		Prostate(47;0.183)		BRCA - Breast invasive adenocarcinoma(232;0.15)														---	---	---	---
TMEM117	84216	broad.mit.edu	37	12	44693525	44693525	+	Intron	SNP	A	G	G			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:44693525A>G	uc001rod.2	+						TMEM117_uc001roe.2_Intron|TMEM117_uc009zkc.2_Intron	NM_032256	NP_115632			transmembrane protein 117							endoplasmic reticulum|integral to membrane					0	Lung SC(27;0.192)			GBM - Glioblastoma multiforme(48;0.124)														---	---	---	---
DGKA	1606	broad.mit.edu	37	12	56334503	56334503	+	Silent	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:56334503C>T	uc001sij.2	+	12	1278	c.1014C>T	c.(1012-1014)GTC>GTT	p.V338V	DGKA_uc009zoc.1_Silent_p.V338V|DGKA_uc001sih.1_Silent_p.V226V|DGKA_uc001sii.1_Silent_p.V196V|DGKA_uc009zod.1_Silent_p.V257V|DGKA_uc001sik.2_Silent_p.V338V|DGKA_uc001sil.2_Silent_p.V338V|DGKA_uc001sim.2_Silent_p.V338V|DGKA_uc001sin.2_Silent_p.V338V|DGKA_uc009zof.2_5'UTR|DGKA_uc001sio.2_Silent_p.V80V	NM_001345	NP_001336	P23743	DGKA_HUMAN	diacylglycerol kinase, alpha 80kDa	338					activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|intracellular signal transduction|platelet activation	plasma membrane	ATP binding|calcium ion binding|diacylglycerol kinase activity			ovary(3)|pancreas(1)	4					Vitamin E(DB00163)											OREG0021913	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	---	---	---	---
DGKA	1606	broad.mit.edu	37	12	56335359	56335359	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:56335359C>T	uc001sij.2	+	15	1505	c.1241C>T	c.(1240-1242)CCT>CTT	p.P414L	DGKA_uc001sih.1_Missense_Mutation_p.P302L|DGKA_uc001sii.1_Missense_Mutation_p.P272L|DGKA_uc009zod.1_Missense_Mutation_p.P333L|DGKA_uc001sik.2_Missense_Mutation_p.P414L|DGKA_uc001sil.2_Missense_Mutation_p.P414L|DGKA_uc001sim.2_Missense_Mutation_p.P414L|DGKA_uc001sin.2_Missense_Mutation_p.P414L|DGKA_uc009zof.2_Missense_Mutation_p.P60L|DGKA_uc001sio.2_Missense_Mutation_p.P156L	NM_001345	NP_001336	P23743	DGKA_HUMAN	diacylglycerol kinase, alpha 80kDa	414	DAGKc.				activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|intracellular signal transduction|platelet activation	plasma membrane	ATP binding|calcium ion binding|diacylglycerol kinase activity			ovary(3)|pancreas(1)	4					Vitamin E(DB00163)													---	---	---	---
SUOX	6821	broad.mit.edu	37	12	56397752	56397752	+	Silent	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr12:56397752C>T	uc001six.2	+	6	905	c.579C>T	c.(577-579)CCC>CCT	p.P193P	SUOX_uc001siy.2_Silent_p.P193P|SUOX_uc001siz.2_Silent_p.P193P|SUOX_uc001sja.2_Silent_p.P193P	NM_000456	NP_000447	P51687	SUOX_HUMAN	sulfite oxidase precursor	193	Molybdenum-pterin domain (By similarity).					mitochondrial intermembrane space	electron carrier activity|molybdenum ion binding|sulfite oxidase activity				0			UCEC - Uterine corpus endometrioid carcinoma (6;0.0471)|OV - Ovarian serous cystadenocarcinoma(18;0.119)															---	---	---	---
MYCBP2	23077	broad.mit.edu	37	13	77671839	77671839	+	Missense_Mutation	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr13:77671839C>T	uc001vkf.2	-	57	9427	c.9336G>A	c.(9334-9336)ATG>ATA	p.M3112I	MYCBP2_uc010aev.2_Missense_Mutation_p.M2516I|MYCBP2_uc001vkg.1_Missense_Mutation_p.M635I|MYCBP2_uc010aew.2_Missense_Mutation_p.M498I	NM_015057	NP_055872	O75592	MYCB2_HUMAN	MYC binding protein 2	3112					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	ligase activity|protein binding|zinc ion binding			ovary(4)|breast(4)|skin(3)|lung(2)|pancreas(1)	14		Breast(118;0.212)|Acute lymphoblastic leukemia(28;0.22)		GBM - Glioblastoma multiforme(99;0.109)														---	---	---	---
FANCM	57697	broad.mit.edu	37	14	45657009	45657009	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr14:45657009G>A	uc001wwd.3	+	19	4797	c.4698G>A	c.(4696-4698)ATG>ATA	p.M1566I	FANCM_uc010anf.2_Missense_Mutation_p.M1540I|FANCM_uc001wwe.3_Missense_Mutation_p.M1102I|FANCM_uc010ang.2_Missense_Mutation_p.M780I	NM_020937	NP_065988	Q8IYD8	FANCM_HUMAN	Fanconi anemia, complementation group M	1566					DNA repair	Fanconi anaemia nuclear complex	ATP binding|ATP-dependent helicase activity|chromatin binding|DNA binding|nuclease activity|protein binding			ovary(3)|lung(2)|breast(2)	7													Involved_in_tolerance_or_repair_of_DNA_crosslinks	Fanconi_Anemia				---	---	---	---
ZFYVE26	23503	broad.mit.edu	37	14	68250043	68250043	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr14:68250043G>A	uc001xka.2	-	21	3965	c.3826C>T	c.(3826-3828)CCG>TCG	p.P1276S	ZFYVE26_uc010tsz.1_RNA|ZFYVE26_uc001xkc.3_Missense_Mutation_p.P1276S	NM_015346	NP_056161	Q68DK2	ZFY26_HUMAN	zinc finger, FYVE domain containing 26	1276					cell cycle|cell death|cytokinesis|double-strand break repair via homologous recombination	centrosome|midbody	metal ion binding|phosphatidylinositol-3-phosphate binding|protein binding			ovary(9)|breast(2)	11				all cancers(60;0.000763)|OV - Ovarian serous cystadenocarcinoma(108;0.0011)|BRCA - Breast invasive adenocarcinoma(234;0.0115)														---	---	---	---
MAPKBP1	23005	broad.mit.edu	37	15	42115796	42115796	+	Silent	SNP	C	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr15:42115796C>A	uc001zok.3	+	30	4054	c.3768C>A	c.(3766-3768)GCC>GCA	p.A1256A	MAPKBP1_uc001zoj.3_Silent_p.A1250A|MAPKBP1_uc010bcj.2_Silent_p.A757A|MAPKBP1_uc010bci.2_Intron|MAPKBP1_uc010udb.1_Silent_p.A1089A|MAPKBP1_uc010bck.2_Silent_p.A467A|MAPKBP1_uc010bcl.2_Silent_p.A757A	NM_001128608	NP_001122080	O60336	MABP1_HUMAN	mitogen-activated protein kinase binding protein	1256										central_nervous_system(5)|breast(2)|upper_aerodigestive_tract(1)|pancreas(1)|skin(1)	10		all_cancers(109;7.71e-14)|all_epithelial(112;5.15e-12)|Lung NSC(122;3.74e-08)|all_lung(180;1.81e-07)|Melanoma(134;0.0262)		OV - Ovarian serous cystadenocarcinoma(18;3.95e-17)|GBM - Glioblastoma multiforme(94;5.71e-07)|Lung(196;0.0436)|BRCA - Breast invasive adenocarcinoma(123;0.203)|LUSC - Lung squamous cell carcinoma(244;0.225)														---	---	---	---
C17orf85	55421	broad.mit.edu	37	17	3716433	3716433	+	Nonsense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:3716433G>A	uc010ckl.1	-	13	1791	c.1768C>T	c.(1768-1770)CAG>TAG	p.Q590*	C17orf85_uc002fwr.2_Nonsense_Mutation_p.Q300*|C17orf85_uc002fwq.2_Nonsense_Mutation_p.Q310*	NM_001114118	NP_001107590	Q53F19	CQ085_HUMAN	ELG protein isoform a	590							nucleotide binding			skin(1)	1				UCEC - Uterine corpus endometrioid carcinoma (3;0.0725)														---	---	---	---
C17orf85	55421	broad.mit.edu	37	17	3716434	3716434	+	Silent	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:3716434C>T	uc010ckl.1	-	13	1790	c.1767G>A	c.(1765-1767)GAG>GAA	p.E589E	C17orf85_uc002fwr.2_Silent_p.E299E|C17orf85_uc002fwq.2_Silent_p.E309E	NM_001114118	NP_001107590	Q53F19	CQ085_HUMAN	ELG protein isoform a	589							nucleotide binding			skin(1)	1				UCEC - Uterine corpus endometrioid carcinoma (3;0.0725)														---	---	---	---
RHBDL3	162494	broad.mit.edu	37	17	30615917	30615917	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:30615917G>A	uc002hhe.1	+	4	415	c.401G>A	c.(400-402)CGA>CAA	p.R134Q	RHBDL3_uc010csw.1_Missense_Mutation_p.R126Q|RHBDL3_uc010csx.1_Missense_Mutation_p.R134Q|RHBDL3_uc010csy.1_Missense_Mutation_p.R36Q|RHBDL3_uc002hhf.1_Missense_Mutation_p.R36Q	NM_138328	NP_612201	P58872	RHBL3_HUMAN	rhomboid protease 3	134					proteolysis	integral to membrane	calcium ion binding|serine-type endopeptidase activity			ovary(1)	1		Breast(31;0.116)|Ovarian(249;0.182)																---	---	---	---
EFTUD2	9343	broad.mit.edu	37	17	42940215	42940215	+	Silent	SNP	G	A	A	rs149288120		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:42940215G>A	uc002ihn.2	-	16	1734	c.1473C>T	c.(1471-1473)CAC>CAT	p.H491H	EFTUD2_uc010wje.1_Silent_p.H456H|EFTUD2_uc010wjf.1_Silent_p.H481H	NM_004247	NP_004238	Q15029	U5S1_HUMAN	elongation factor Tu GTP binding domain	491						Cajal body|catalytic step 2 spliceosome|cytoplasm|nuclear speck	GTP binding|GTPase activity|protein binding			ovary(1)	1		Prostate(33;0.109)																---	---	---	---
PPP4R1	9989	broad.mit.edu	37	18	9595144	9595144	+	Silent	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr18:9595144C>T	uc002koe.1	-	3	178	c.60G>A	c.(58-60)GTG>GTA	p.V20V	PPP4R1_uc010wzo.1_5'UTR|PPP4R1_uc002kod.1_Intron|PPP4R1_uc010wzp.1_Intron	NM_001042388	NP_001035847	Q8TF05	PP4R1_HUMAN	protein phosphatase 4, regulatory subunit 1	20	HEAT 1.				protein phosphorylation|signal transduction	protein phosphatase 4 complex	protein binding|protein phosphatase type 4 regulator activity			skin(1)	1																		---	---	---	---
SUPT5H	6829	broad.mit.edu	37	19	39960816	39960816	+	Missense_Mutation	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:39960816G>A	uc002olo.3	+	17	1611	c.1432G>A	c.(1432-1434)GTG>ATG	p.V478M	SUPT5H_uc002olp.3_Missense_Mutation_p.V478M|SUPT5H_uc002olq.3_Missense_Mutation_p.V474M|SUPT5H_uc002oln.3_Missense_Mutation_p.V478M|SUPT5H_uc002olr.3_Missense_Mutation_p.V478M|SUPT5H_uc002ols.1_Missense_Mutation_p.V101M|SUPT5H_uc010egp.1_5'Flank	NM_001111020	NP_001104490	O00267	SPT5H_HUMAN	suppressor of Ty 5 homolog isoform a	478	KOW 3.				cell cycle|chromatin remodeling|mRNA capping|negative regulation of transcription elongation, DNA-dependent|negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription elongation from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of viral transcription|response to organic substance|retroviral genome replication|transcription elongation from RNA polymerase II promoter	nucleoplasm	enzyme binding|protein heterodimerization activity			ovary(3)|pancreas(1)	4	all_cancers(60;6.69e-07)|all_lung(34;2.66e-08)|Lung NSC(34;3e-08)|all_epithelial(25;1.57e-06)|Ovarian(47;0.159)		Epithelial(26;3.9e-26)|all cancers(26;1.35e-23)|LUSC - Lung squamous cell carcinoma(53;0.000657)															---	---	---	---
CKM	1158	broad.mit.edu	37	19	45815134	45815134	+	Silent	SNP	G	A	A			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:45815134G>A	uc002pbd.2	-	5	600	c.526C>T	c.(526-528)CTG>TTG	p.L176L		NM_001824	NP_001815	P06732	KCRM_HUMAN	muscle creatine kinase	176	Phosphagen kinase C-terminal.				creatine metabolic process	cytosol	ATP binding|creatine kinase activity			skin(1)	1		Ovarian(192;0.0336)|all_neural(266;0.112)		OV - Ovarian serous cystadenocarcinoma(262;2.29e-44)|Epithelial(262;1.05e-38)|GBM - Glioblastoma multiforme(486;3.56e-07)	Creatine(DB00148)													---	---	---	---
ZNF419	79744	broad.mit.edu	37	19	58003627	58003627	+	Intron	SNP	C	T	T			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:58003627C>T	uc002qov.2	+						ZNF547_uc002qpm.3_Intron|ZNF419_uc010ety.1_Intron|ZNF419_uc010etz.1_Intron|ZNF419_uc010eua.1_Intron|ZNF419_uc002qow.2_Intron|ZNF419_uc010eub.1_Intron|ZNF419_uc010euc.1_Intron	NM_024691	NP_078967			zinc finger protein 419 isoform 2						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		Colorectal(82;5.46e-05)|all_neural(62;0.0218)|Ovarian(87;0.0694)|Breast(46;0.0848)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0252)|Lung(386;0.171)														---	---	---	---
EMILIN3	90187	broad.mit.edu	37	20	39991532	39991532	+	Missense_Mutation	SNP	A	G	G			TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr20:39991532A>G	uc002xjy.1	-	4	901	c.677T>C	c.(676-678)TTT>TCT	p.F226S		NM_052846	NP_443078	Q9NT22	EMIL3_HUMAN	elastin microfibril interfacer 3	226						proteinaceous extracellular matrix				ovary(1)	1		Myeloproliferative disorder(115;0.00425)																---	---	---	---
IDH3G	3421	broad.mit.edu	37	X	153052343	153052343	+	Silent	SNP	G	A	A	rs141309746		TCGA-CD-5802-01	TCGA-CD-5802-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chrX:153052343G>A	uc004fip.2	-	10	1023	c.837C>T	c.(835-837)ATC>ATT	p.I279I	IDH3G_uc004fio.2_Silent_p.I221I|IDH3G_uc004fiq.2_Silent_p.I279I|IDH3G_uc010num.2_Silent_p.I221I|IDH3G_uc004fir.2_Silent_p.I221I|IDH3G_uc004fit.1_Silent_p.I279I|IDH3G_uc004fis.2_Silent_p.I221I|IDH3G_uc004fiu.2_Silent_p.I55I	NM_004135	NP_004126	P51553	IDH3G_HUMAN	isocitrate dehydrogenase 3 (NAD+) gamma isoform	279					carbohydrate metabolic process|isocitrate metabolic process|tricarboxylic acid cycle	mitochondrial matrix|nucleolus	ATP binding|isocitrate dehydrogenase (NAD+) activity|magnesium ion binding|NAD binding				0	all_hematologic(71;4.25e-06)|all_lung(58;3.83e-05)|Lung NSC(58;5.54e-05)|Acute lymphoblastic leukemia(192;6.56e-05)				NADH(DB00157)													---	---	---	---
