Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_status	validation_method	validation_tumor_sample	validation_alt_allele
WASF2	10163	broad.mit.edu	37	1	27755512	27755513	+	Intron	DEL	TT	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:27755512_27755513delTT	uc001bof.1	-						WASF2_uc010ofl.1_Intron	NM_006990	NP_008921			WAS protein family, member 2						actin cytoskeleton organization|G-protein signaling, coupled to cAMP nucleotide second messenger	actin cytoskeleton|lamellipodium	actin binding			skin(2)|ovary(1)	3		all_lung(284;1.06e-05)|Lung NSC(340;1.86e-05)|Colorectal(325;3.46e-05)|Renal(390;0.0007)|Breast(348;0.0021)|Ovarian(437;0.00503)|Myeloproliferative disorder(586;0.0255)|all_neural(195;0.0381)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0446)|OV - Ovarian serous cystadenocarcinoma(117;2.46e-25)|Colorectal(126;1.7e-08)|COAD - Colon adenocarcinoma(152;2e-06)|BRCA - Breast invasive adenocarcinoma(304;0.00139)|KIRC - Kidney renal clear cell carcinoma(1967;0.00204)|STAD - Stomach adenocarcinoma(196;0.00325)|READ - Rectum adenocarcinoma(331;0.0481)														---	---	---	---
Unknown	0	broad.mit.edu	37	1	31128106	31128111	+	IGR	DEL	TGGTGA	-	-	rs112746252		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:31128106_31128111delTGGTGA								None (None upstream) : MATN1 (56015 downstream)																																			---	---	---	---
MACF1	23499	broad.mit.edu	37	1	39796845	39796855	+	5'UTR	DEL	TTTTTTTTTTT	-	-	rs71810789		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:39796845_39796855delTTTTTTTTTTT	uc010oiu.1	+	1					MACF1_uc010ois.1_Intron|MACF1_uc001cda.1_Intron|MACF1_uc001cdc.1_Intron|MACF1_uc001cdb.1_Intron	NM_033044	NP_149033			microfilament and actin filament cross-linker						cell cycle arrest|Golgi to plasma membrane protein transport|positive regulation of Wnt receptor signaling pathway|regulation of epithelial cell migration|regulation of focal adhesion assembly|regulation of microtubule-based process|Wnt receptor signaling pathway|wound healing	Golgi apparatus|microtubule|ruffle membrane	actin filament binding|ATPase activity|calcium ion binding|microtubule binding			ovary(8)|breast(3)|central_nervous_system(3)|skin(2)	16	Lung NSC(20;5.57e-06)|Ovarian(52;0.00769)|Acute lymphoblastic leukemia(166;0.074)	Myeloproliferative disorder(586;0.0255)	OV - Ovarian serous cystadenocarcinoma(33;7.78e-19)|Epithelial(16;1.73e-17)|all cancers(16;2.49e-16)|LUSC - Lung squamous cell carcinoma(16;0.00146)|Lung(16;0.00204)															---	---	---	---
IL23R	149233	broad.mit.edu	37	1	67672567	67672568	+	Intron	INS	-	T	T	rs79547341		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:67672567_67672568insT	uc001ddo.2	+						IL23R_uc009waz.2_Intron|IL23R_uc001ddp.2_Intron|IL23R_uc010opi.1_Intron|IL23R_uc010opj.1_Intron|IL23R_uc010opk.1_Intron|IL23R_uc010opl.1_Intron|IL23R_uc010opm.1_Intron|IL23R_uc001ddq.2_Intron|IL23R_uc010opn.1_Intron|IL23R_uc001ddr.2_Intron|IL23R_uc010opo.1_Intron|IL23R_uc010opp.1_Intron|IL23R_uc010opq.1_Intron|IL23R_uc010opr.1_Intron|IL23R_uc010ops.1_Intron|IL23R_uc010opt.1_Intron|IL23R_uc010opu.1_Intron|IL23R_uc010opv.1_Intron|IL23R_uc010opw.1_Intron|IL23R_uc010opx.1_Intron|IL23R_uc010opy.1_Intron|IL23R_uc010opz.1_Intron|IL23R_uc010oqa.1_Intron|IL23R_uc010oqb.1_Intron|IL23R_uc010oqc.1_Intron|IL23R_uc010oqd.1_Intron|IL23R_uc010oqe.1_Intron|IL23R_uc010oqf.1_Intron|IL23R_uc010oqg.1_Intron|IL23R_uc010oqh.1_Intron|IL23R_uc001dds.2_5'Flank|IL23R_uc001ddt.2_5'Flank	NM_144701	NP_653302			interleukin 23 receptor precursor						inflammatory response|negative regulation of interleukin-10 production|positive regulation of defense response to virus by host|positive regulation of interferon-gamma production|positive regulation of interleukin-12 production|positive regulation of memory T cell differentiation|positive regulation of T cell mediated cytotoxicity|positive regulation of T-helper 1 type immune response|positive regulation of T-helper 17 cell lineage commitment|positive regulation of T-helper 17 type immune response|response to interferon-gamma|response to lipopolysaccharide	interleukin-23 receptor complex	receptor activity				0																		---	---	---	---
SLC35A3	23443	broad.mit.edu	37	1	100459463	100459464	+	Intron	INS	-	ATTTT	ATTTT	rs140455064	by1000genomes	TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:100459463_100459464insATTTT	uc001dsp.1	+						SLC35A3_uc001dsq.1_Intron|SLC35A3_uc009wdy.1_Intron|SLC35A3_uc001dsr.1_Intron|SLC35A3_uc001dss.1_Intron	NM_012243	NP_036375			solute carrier family 35 member 3A						UDP-N-acetylglucosamine metabolic process	Golgi membrane|integral to membrane	sugar:hydrogen symporter activity|UDP-N-acetylglucosamine transmembrane transporter activity				0		all_epithelial(167;0.000686)|all_lung(203;0.0154)|Lung NSC(277;0.0155)		Epithelial(280;0.124)|all cancers(265;0.198)|Lung(183;0.199)														---	---	---	---
NBPF9	400818	broad.mit.edu	37	1	144220693	144220694	+	Intron	INS	-	C	C			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:144220693_144220694insC	uc010oxr.1	+						NBPF9_uc010oxn.1_Intron|NBPF9_uc010oxo.1_Intron|NBPF9_uc010oxt.1_Intron|NBPF9_uc001ekg.1_Intron|NBPF9_uc001ekk.1_Intron|NBPF10_uc009wir.2_Intron|NBPF9_uc010oyd.1_Intron|uc010oxz.1_Intron	NM_001037675	NP_001032764			hypothetical protein LOC400818							cytoplasm					0																		---	---	---	---
EIF2AK3	9451	broad.mit.edu	37	2	88892666	88892667	+	Intron	DEL	AT	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:88892666_88892667delAT	uc002stc.3	-							NM_004836	NP_004827			eukaryotic translation initiation factor 2-alpha						activation of caspase activity|bone mineralization|calcium-mediated signaling|chondrocyte development|endocrine pancreas development|endoplasmic reticulum organization|endoplasmic reticulum unfolded protein response|ER overload response|insulin secretion|insulin-like growth factor receptor signaling pathway|negative regulation of myelination|negative regulation of translational initiation in response to stress|protein autophosphorylation|protein homooligomerization	endoplasmic reticulum membrane|integral to membrane	ATP binding|eukaryotic translation initiation factor 2alpha kinase activity|identical protein binding			ovary(3)	3																		---	---	---	---
STARD7	56910	broad.mit.edu	37	2	96852843	96852843	+	Intron	DEL	A	-	-	rs79652198		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:96852843delA	uc002svm.3	-						STARD7_uc002svl.2_Intron	NM_020151	NP_064536			START domain containing 7 precursor							mitochondrion					0																		---	---	---	---
MAP3K2	10746	broad.mit.edu	37	2	128084175	128084176	+	Intron	DEL	AC	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:128084175_128084176delAC	uc002toj.1	-						MAP3K2_uc010flz.1_Intron	NM_006609	NP_006600			mitogen-activated protein kinase kinase kinase						activation of JUN kinase activity|cellular response to mechanical stimulus	nucleus	ATP binding|MAP kinase kinase kinase activity|metal ion binding|protein kinase binding			lung(3)|ovary(2)|large_intestine(1)|central_nervous_system(1)	7	Colorectal(110;0.1)			BRCA - Breast invasive adenocarcinoma(221;0.0706)														---	---	---	---
UGDH	7358	broad.mit.edu	37	4	39507525	39507525	+	Intron	DEL	A	-	-	rs35867925		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr4:39507525delA	uc003guk.1	-						UGDH_uc011byp.1_Intron|UGDH_uc003gul.1_Intron	NM_003359	NP_003350			UDP-glucose dehydrogenase						glycosaminoglycan biosynthetic process|UDP-glucose metabolic process|UDP-glucuronate biosynthetic process|xenobiotic metabolic process	cytosol	electron carrier activity|NAD binding|UDP-glucose 6-dehydrogenase activity			large_intestine(1)|ovary(1)|central_nervous_system(1)|skin(1)	4					NADH(DB00157)													---	---	---	---
C4orf21	55345	broad.mit.edu	37	4	113486605	113486606	+	Intron	INS	-	T	T	rs150011350		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr4:113486605_113486606insT	uc003iau.2	-						C4orf21_uc003iav.2_Intron	NM_018392	NP_060862			prematurely terminated mRNA decay factor-like							integral to membrane	zinc ion binding				0		Ovarian(17;0.156)		OV - Ovarian serous cystadenocarcinoma(123;0.000676)														---	---	---	---
IRF1	3659	broad.mit.edu	37	5	131821520	131821521	+	Intron	INS	-	AC	AC	rs142244361	by1000genomes	TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr5:131821520_131821521insAC	uc003kxa.2	-						C5orf56_uc010jds.1_Intron|IRF1_uc003kxd.2_Intron|IRF1_uc003kxb.2_Intron|IRF1_uc010jdt.1_Intron	NM_002198	NP_002189			interferon regulatory factor 1						blood coagulation|cellular response to mechanical stimulus|interferon-gamma-mediated signaling pathway|transcription from RNA polymerase II promoter|type I interferon-mediated signaling pathway	nucleoplasm					0		all_cancers(142;0.026)|Breast(839;0.198)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)	LUAD - Lung adenocarcinoma(142;0.247)														---	---	---	---
Unknown	0	broad.mit.edu	37	6	53219905	53219905	+	IGR	DEL	A	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:53219905delA								ELOVL5 (5963 upstream) : GCLC (142235 downstream)																																			---	---	---	---
Unknown	0	broad.mit.edu	37	7	55659698	55659698	+	IGR	DEL	A	-	-	rs150658197	by1000genomes	TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:55659698delA								VOPP1 (19498 upstream) : LOC442308 (53614 downstream)																																			---	---	---	---
Unknown	0	broad.mit.edu	37	7	57274473	57274476	+	IGR	DEL	TCTT	-	-	rs150621884		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:57274473_57274476delTCTT								ZNF479 (66902 upstream) : ZNF716 (235407 downstream)																																			---	---	---	---
SRCRB4D	136853	broad.mit.edu	37	7	76021278	76021278	+	Intron	DEL	T	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:76021278delT	uc003ufb.2	-						SRCRB4D_uc003ufa.2_Intron	NM_080744	NP_542782			scavenger receptor cysteine rich domain							extracellular region|membrane	scavenger receptor activity			pancreas(1)	1																		---	---	---	---
Unknown	0	broad.mit.edu	37	8	55243464	55243464	+	IGR	DEL	A	-	-	rs35886430		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr8:55243464delA								MRPL15 (182390 upstream) : SOX17 (127031 downstream)																																			---	---	---	---
Unknown	0	broad.mit.edu	37	8	96415908	96415918	+	IGR	DEL	TTTTTTTTTTT	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr8:96415908_96415918delTTTTTTTTTTT								C8orf37 (134471 upstream) : GDF6 (738642 downstream)																																			---	---	---	---
RCL1	10171	broad.mit.edu	37	9	4850493	4850493	+	Intron	DEL	C	-	-	rs10974811		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:4850493delC	uc003zis.2	+						RCL1_uc003zit.2_Intron|RCL1_uc010mhk.1_Intron|RCL1_uc010mhl.1_Intron	NM_005772	NP_005763			RNA terminal phosphate cyclase-like 1						ribosome biogenesis|RNA processing	nucleolus	RNA-3'-phosphate cyclase activity				0	all_hematologic(13;0.137)	Acute lymphoblastic leukemia(23;0.0206)|Breast(48;0.147)		GBM - Glioblastoma multiforme(50;0.0244)														---	---	---	---
Unknown	0	broad.mit.edu	37	9	66708540	66708541	+	IGR	DEL	AC	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:66708540_66708541delAC								LOC442421 (205513 upstream) : AQP7P1 (545726 downstream)																																			---	---	---	---
ANKRD20A4	728747	broad.mit.edu	37	9	69391298	69391299	+	Intron	INS	-	TA	TA			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:69391298_69391299insTA	uc004afn.2	+						ANKRD20A4_uc010mnw.1_Intron	NM_001098805	NP_001092275			ankyrin repeat domain 20 family, member A4												0																		---	---	---	---
RPSAP9	653162	broad.mit.edu	37	9	79014569	79014570	+	3'UTR	INS	-	A	A			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:79014569_79014570insA	uc011lsj.1	+	1						NR_026890				SubName: Full=Laminin receptor-like protein LAMRL5;												0																		---	---	---	---
Unknown	0	broad.mit.edu	37	9	98910246	98910246	+	IGR	DEL	A	-	-	rs139074595		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:98910246delA								NCRNA00092 (126209 upstream) : HSD17B3 (87343 downstream)																																			---	---	---	---
CACNA1B	774	broad.mit.edu	37	9	140777551	140777552	+	Intron	INS	-	GGAA	GGAA	rs140080287	by1000genomes	TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:140777551_140777552insGGAA	uc004cog.2	+						uc004cof.1_Intron	NM_000718	NP_000709			calcium channel, voltage-dependent, N type,						membrane depolarization|synaptic transmission	voltage-gated calcium channel complex	ATP binding|protein C-terminus binding|voltage-gated calcium channel activity			breast(3)|large_intestine(2)|ovary(1)	6	all_cancers(76;0.166)			OV - Ovarian serous cystadenocarcinoma(145;1.16e-05)|Epithelial(140;0.000476)	Amlodipine(DB00381)|Gabapentin(DB00996)													---	---	---	---
Unknown	0	broad.mit.edu	37	10	42672240	42672241	+	IGR	INS	-	TAAG	TAAG	rs71529068		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr10:42672240_42672241insTAAG								None (None upstream) : LOC441666 (155074 downstream)																																			---	---	---	---
COL13A1	1305	broad.mit.edu	37	10	71664679	71664679	+	Intron	DEL	G	-	-	rs71931678		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr10:71664679delG	uc001jpr.1	+						COL13A1_uc001jqj.1_Intron|COL13A1_uc001jps.1_Intron|COL13A1_uc001jpt.1_Intron|COL13A1_uc001jpu.1_Intron|COL13A1_uc001jpv.1_Intron|COL13A1_uc001jpx.1_Intron|COL13A1_uc001jpw.1_Intron|COL13A1_uc001jpy.1_Intron|COL13A1_uc001jpz.1_Intron|COL13A1_uc001jqa.1_Intron|COL13A1_uc001jqc.1_Intron|COL13A1_uc001jqb.1_Intron|COL13A1_uc001jql.2_Intron|COL13A1_uc001jqd.1_Intron|COL13A1_uc001jqe.1_Intron|COL13A1_uc001jqf.1_Intron|COL13A1_uc001jqg.1_Intron|COL13A1_uc001jqh.1_Intron|COL13A1_uc001jqi.1_Intron|COL13A1_uc010qjf.1_Intron|COL13A1_uc001jqk.1_Intron	NM_005203	NP_005194			alpha 1 type XIII collagen isoform 1						cell differentiation|cell-cell adhesion|cell-matrix adhesion|endochondral ossification|morphogenesis of a branching structure	collagen type XIII|integral to membrane	extracellular matrix structural constituent|heparin binding|protein binding			ovary(1)	1					Atorvastatin(DB01076)|Simvastatin(DB00641)													---	---	---	---
KIF20B	9585	broad.mit.edu	37	10	91503836	91503836	+	Intron	DEL	A	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr10:91503836delA	uc001kgs.1	+						KIF20B_uc001kgr.1_Intron|KIF20B_uc001kgt.1_Intron|KIF20B_uc009xtw.1_Intron	NM_016195	NP_057279			M-phase phosphoprotein 1						cell cycle arrest|cell division|microtubule-based movement|mitosis|regulation of mitosis	centrosome|microtubule|nucleolus|nucleoplasm|spindle	ATP binding|ATPase activity|microtubule motor activity|WW domain binding			ovary(1)|pancreas(1)|skin(1)	3																		---	---	---	---
PLEKHA7	144100	broad.mit.edu	37	11	16996173	16996174	+	Intron	INS	-	T	T	rs140380478		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr11:16996173_16996174insT	uc001mmo.2	-						PLEKHA7_uc010rcu.1_Intron	NM_175058	NP_778228			pleckstrin homology domain containing, family A						epithelial cell-cell adhesion|zonula adherens maintenance	centrosome|zonula adherens	delta-catenin binding			skin(2)|central_nervous_system(1)	3																		---	---	---	---
SPATA13	221178	broad.mit.edu	37	13	24876598	24876608	+	Intron	DEL	AAAAAAAAAAA	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr13:24876598_24876608delAAAAAAAAAAA	uc001upg.1	+						SPATA13_uc001upd.1_Intron|C1QTNF9_uc001upe.2_Intron|SPATA13_uc010tcy.1_Intron|SPATA13_uc010tcz.1_Intron|SPATA13_uc010tda.1_Intron|SPATA13_uc001uph.2_Intron|SPATA13_uc010tdb.1_Intron|SPATA13_uc009zzz.1_Intron	NM_153023	NP_694568			spermatogenesis associated 13						cell migration|filopodium assembly|lamellipodium assembly|regulation of cell migration|regulation of Rho protein signal transduction	cytoplasm|filopodium|lamellipodium|ruffle membrane	protein binding|Rac guanyl-nucleotide exchange factor activity			skin(2)|ovary(1)	3		all_cancers(29;4.05e-15)|all_lung(29;2.77e-14)|all_epithelial(30;7.77e-13)|Lung SC(185;0.0279)		all cancers(112;0.00616)|Epithelial(112;0.0195)|OV - Ovarian serous cystadenocarcinoma(117;0.0705)|Lung(94;0.231)														---	---	---	---
GABPB1	2553	broad.mit.edu	37	15	50581976	50581977	+	Intron	INS	-	TTTTTTT	TTTTTTT	rs140176493	by1000genomes	TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr15:50581976_50581977insTTTTTTT	uc001zyb.2	-						GABPB1_uc001zya.2_Intron|GABPB1_uc010ufg.1_Intron|GABPB1_uc001zyc.2_Intron|GABPB1_uc001zyd.2_Intron|GABPB1_uc001zye.2_Intron|GABPB1_uc001zyf.2_Intron	NM_005254	NP_005245			GA binding protein transcription factor, beta						positive regulation of transcription from RNA polymerase II promoter	nucleus	protein binding|protein heterodimerization activity|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding			large_intestine(1)	1																		---	---	---	---
RNF111	54778	broad.mit.edu	37	15	59341562	59341564	+	Intron	DEL	TTT	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr15:59341562_59341564delTTT	uc002afv.2	+						RNF111_uc002afs.2_Intron|RNF111_uc002aft.2_Intron|RNF111_uc002afu.2_Intron|RNF111_uc002afw.2_Intron	NM_017610	NP_060080			ring finger protein 111						multicellular organismal development|positive regulation of transcription, DNA-dependent	cytoplasm|nucleus	protein binding|ubiquitin-protein ligase activity|zinc ion binding			ovary(2)	2				all cancers(107;0.194)														---	---	---	---
CCDC135	84229	broad.mit.edu	37	16	57748547	57748548	+	Intron	DEL	CA	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr16:57748547_57748548delCA	uc002emi.2	+						CCDC135_uc002emj.2_Intron|CCDC135_uc002emk.2_Intron	NM_032269	NP_115645			coiled-coil domain containing 135							cytoplasm				central_nervous_system(1)	1																		---	---	---	---
CLEC18C	283971	broad.mit.edu	37	16	70045704	70045704	+	Intron	DEL	C	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr16:70045704delC	uc002exy.2	+						PDXDC2_uc002eyb.2_Intron|PDXDC2_uc002eyc.2_Intron	NM_182619	NP_872425			secretory protein LOC348174 precursor							extracellular region	sugar binding				0																		---	---	---	---
SERPINF1	5176	broad.mit.edu	37	17	1674544	1674544	+	Intron	DEL	C	-	-			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:1674544delC	uc002ftl.2	+						SERPINF1_uc010cjw.2_Intron	NM_002615	NP_002606			serine (or cysteine) proteinase inhibitor, clade						cell proliferation|negative regulation of angiogenesis|positive regulation of neurogenesis|regulation of proteolysis	extracellular space|melanosome	serine-type endopeptidase inhibitor activity			ovary(1)	1																		---	---	---	---
C17orf98	388381	broad.mit.edu	37	17	36993201	36993202	+	Intron	INS	-	A	A	rs113691927		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:36993201_36993202insA	uc002hqv.2	-							NM_001080465	NP_001073934			hypothetical protein LOC388381												0																		---	---	---	---
TSEN54	283989	broad.mit.edu	37	17	73513416	73513416	+	Intron	DEL	T	-	-	rs11316466		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:73513416delT	uc002jof.1	+						CASKIN2_uc002joc.2_5'Flank|CASKIN2_uc002jod.2_5'Flank|TSEN54_uc002joe.1_Intron	NM_207346	NP_997229			tRNA splicing endonuclease 54 homolog						mRNA processing|tRNA splicing, via endonucleolytic cleavage and ligation	nucleolus				ovary(1)	1	all_cancers(13;3.15e-09)|all_epithelial(9;5.78e-10)|Breast(9;5.8e-10)|all_lung(278;0.246)		all cancers(21;4.57e-07)|Epithelial(20;2.92e-06)|Lung(188;0.0809)|LUSC - Lung squamous cell carcinoma(166;0.154)															---	---	---	---
Unknown	0	broad.mit.edu	37	19	44917439	44917446	+	IGR	DEL	TTCCTTCC	-	-	rs112103963		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:44917439_44917446delTTCCTTCC								ZFP112 (11662 upstream) : ZNF229 (12980 downstream)																																			---	---	---	---
C21orf29	54084	broad.mit.edu	37	21	46116981	46116984	+	Intron	DEL	CGCT	-	-	rs66738587	by1000genomes	TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr21:46116981_46116984delCGCT	uc002zfe.1	-						C21orf29_uc010gpv.1_Intron|KRTAP10-12_uc002zfw.1_5'Flank	NM_144991	NP_659428			chromosome 21 open reading frame 29 precursor						cell adhesion	extracellular region	structural molecule activity				0																		---	---	---	---
Unknown	0	broad.mit.edu	37	Y	13601466	13601467	+	IGR	INS	-	T	T	rs112972965		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chrY:13601466_13601467insT								None (None upstream) : None (None downstream)																																			---	---	---	---
ZNF644	84146	broad.mit.edu	37	1	91406870	91406870	+	Intron	SNP	G	C	C			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:91406870G>C	uc001dnw.2	-						ZNF644_uc001dnv.2_Intron|ZNF644_uc001dnx.2_Intron|ZNF644_uc001dny.1_Intron	NM_201269	NP_958357			zinc finger protein 644 isoform 1						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)|breast(1)|skin(1)	3		all_lung(203;0.00206)|Lung NSC(277;0.0519)|Lung SC(238;0.101)		all cancers(265;0.00102)|Epithelial(280;0.00766)|KIRC - Kidney renal clear cell carcinoma(1967;0.147)|OV - Ovarian serous cystadenocarcinoma(397;0.173)														---	---	---	---
RGS16	6004	broad.mit.edu	37	1	182569616	182569616	+	Silent	SNP	C	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:182569616C>T	uc001gpl.3	-	5	574	c.420G>A	c.(418-420)ACG>ACA	p.T140T		NM_002928	NP_002919	O15492	RGS16_HUMAN	regulator of G-protein signalling 16	140	RGS.				negative regulation of signal transduction|regulation of G-protein coupled receptor protein signaling pathway|visual perception	cytoplasm|plasma membrane	calmodulin binding|GTPase activator activity|signal transducer activity			ovary(1)	1																		---	---	---	---
HHAT	55733	broad.mit.edu	37	1	210522387	210522387	+	Missense_Mutation	SNP	A	T	T	rs138327418	byFrequency	TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:210522387A>T	uc009xcx.2	+	2	234	c.68A>T	c.(67-69)TAT>TTT	p.Y23F	HHAT_uc010psq.1_Missense_Mutation_p.Y23F|HHAT_uc001hhz.3_Missense_Mutation_p.Y23F|HHAT_uc010psr.1_Intron|HHAT_uc010pss.1_Missense_Mutation_p.M1L|HHAT_uc009xcy.2_Missense_Mutation_p.Y23F|HHAT_uc010pst.1_Intron|HHAT_uc010psu.1_Missense_Mutation_p.Y23F	NM_001122834	NP_001116306	Q5VTY9	HHAT_HUMAN	hedgehog acyltransferase	23	Helical; (Potential).				multicellular organismal development	endoplasmic reticulum membrane|integral to membrane	GTP binding			ovary(2)	2				OV - Ovarian serous cystadenocarcinoma(81;0.0136)|all cancers(67;0.161)|KIRC - Kidney renal clear cell carcinoma(1967;0.215)														---	---	---	---
TGFB2	7042	broad.mit.edu	37	1	218609423	218609423	+	Missense_Mutation	SNP	A	G	G			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr1:218609423A>G	uc001hlm.2	+	5	1519	c.866A>G	c.(865-867)TAC>TGC	p.Y289C	TGFB2_uc001hln.2_Missense_Mutation_p.Y317C|TGFB2_uc010pue.1_Intron|TGFB2_uc001hlo.2_Intron	NM_003238	NP_003229	P61812	TGFB2_HUMAN	transforming growth factor, beta 2 isoform 2	289					activation of protein kinase activity|angiogenesis|cardiac epithelial to mesenchymal transition|cardiac muscle cell proliferation|cardioblast differentiation|catagen|cell cycle arrest|cell death|cell growth|cell-cell junction organization|cell-cell signaling|collagen fibril organization|dopamine biosynthetic process|embryonic digestive tract development|eye development|glial cell migration|hair follicle morphogenesis|hemopoiesis|menstrual cycle phase|negative regulation of alkaline phosphatase activity|negative regulation of cell growth|negative regulation of epithelial cell proliferation|negative regulation of immune response|negative regulation of macrophage cytokine production|neuron development|neutrophil chemotaxis|odontogenesis|pathway-restricted SMAD protein phosphorylation|platelet activation|platelet degranulation|positive regulation of cardioblast differentiation|positive regulation of catagen|positive regulation of cell adhesion mediated by integrin|positive regulation of cell cycle|positive regulation of cell division|positive regulation of cell growth|positive regulation of cell proliferation|positive regulation of epithelial cell migration|positive regulation of epithelial to mesenchymal transition|positive regulation of heart contraction|positive regulation of immune response|positive regulation of integrin biosynthetic process|positive regulation of neuron apoptosis|positive regulation of ossification|positive regulation of phosphatidylinositol 3-kinase cascade|positive regulation of protein secretion|positive regulation of stress-activated MAPK cascade|regulation of transforming growth factor-beta2 production|response to hypoxia|response to progesterone stimulus|salivary gland morphogenesis|SMAD protein import into nucleus|somatic stem cell division|transforming growth factor beta receptor signaling pathway	axon|extracellular matrix|extracellular space|neuronal cell body|platelet alpha granule lumen	beta-amyloid binding|cytokine activity|growth factor activity|protein heterodimerization activity|protein homodimerization activity|receptor signaling protein serine/threonine kinase activity|type II transforming growth factor beta receptor binding				0				all cancers(67;0.0459)|OV - Ovarian serous cystadenocarcinoma(81;0.049)|GBM - Glioblastoma multiforme(131;0.0776)														---	---	---	---
TPO	7173	broad.mit.edu	37	2	1488414	1488414	+	Missense_Mutation	SNP	C	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:1488414C>T	uc002qww.2	+	9	1476	c.1385C>T	c.(1384-1386)GCC>GTC	p.A462V	TPO_uc010ewj.2_RNA|TPO_uc002qwu.2_Missense_Mutation_p.A462V|TPO_uc002qwr.2_Missense_Mutation_p.A462V|TPO_uc002qwx.2_Missense_Mutation_p.A462V|TPO_uc010yio.1_Missense_Mutation_p.A289V|TPO_uc010yip.1_Missense_Mutation_p.A462V|TPO_uc002qwy.1_5'UTR|TPO_uc002qwz.2_RNA	NM_000547	NP_000538	P07202	PERT_HUMAN	thyroid peroxidase isoform a	462	Extracellular (Potential).				cellular nitrogen compound metabolic process|hormone biosynthetic process|hydrogen peroxide catabolic process	cell surface|cytoplasm|integral to plasma membrane	calcium ion binding|heme binding|iodide peroxidase activity			ovary(7)|pancreas(6)|skin(5)|lung(1)|kidney(1)	20	all_hematologic(175;0.0487)|Acute lymphoblastic leukemia(172;0.0627)	all_cancers(51;0.0338)		all cancers(51;0.0356)|OV - Ovarian serous cystadenocarcinoma(76;0.0748)|Epithelial(75;0.12)	Carbimazole(DB00389)|Methimazole(DB00763)|Propylthiouracil(DB00550)													---	---	---	---
EFEMP1	2202	broad.mit.edu	37	2	56144850	56144850	+	Missense_Mutation	SNP	C	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:56144850C>T	uc002rzh.2	-	4	797	c.467G>A	c.(466-468)CGT>CAT	p.R156H	EFEMP1_uc002rzi.2_Missense_Mutation_p.R156H|EFEMP1_uc002rzj.2_Missense_Mutation_p.R156H|EFEMP1_uc010ypc.1_Missense_Mutation_p.R98H	NM_004105	NP_004096	Q12805	FBLN3_HUMAN	EGF-containing fibulin-like extracellular matrix	156					negative regulation of chondrocyte differentiation|peptidyl-tyrosine phosphorylation|regulation of transcription, DNA-dependent|visual perception	extracellular space|proteinaceous extracellular matrix	calcium ion binding|epidermal growth factor receptor activity|epidermal growth factor receptor binding|growth factor activity			ovary(4)|pancreas(1)|skin(1)	6			LUSC - Lung squamous cell carcinoma(58;0.127)|Lung(47;0.132)															---	---	---	---
KCNH7	90134	broad.mit.edu	37	2	163228443	163228443	+	Missense_Mutation	SNP	C	A	A	rs142210415		TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:163228443C>A	uc002uch.1	-	16	3699	c.3487G>T	c.(3487-3489)GTT>TTT	p.V1163F		NM_033272	NP_150375	Q9NS40	KCNH7_HUMAN	potassium voltage-gated channel, subfamily H,	1163	Cytoplasmic (Potential).				regulation of transcription, DNA-dependent	integral to membrane	protein binding|signal transducer activity			ovary(3)|skin(2)	5					Ibutilide(DB00308)													---	---	---	---
KLHL30	377007	broad.mit.edu	37	2	239057799	239057799	+	Intron	SNP	C	A	A			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr2:239057799C>A	uc002vxr.1	+							NM_198582	NP_940984			kelch-like 30												0		Breast(86;7.61e-05)|Renal(207;0.00183)|Ovarian(221;0.0481)|all_hematologic(139;0.158)|all_lung(227;0.198)|Melanoma(123;0.203)|Hepatocellular(293;0.244)		Epithelial(121;4.71e-24)|OV - Ovarian serous cystadenocarcinoma(60;3.02e-12)|Kidney(56;3.04e-09)|KIRC - Kidney renal clear cell carcinoma(57;5.63e-08)|BRCA - Breast invasive adenocarcinoma(100;0.000109)|Lung(119;0.0108)|LUSC - Lung squamous cell carcinoma(224;0.0253)														---	---	---	---
CCK	885	broad.mit.edu	37	3	42299654	42299654	+	Missense_Mutation	SNP	C	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr3:42299654C>T	uc003clc.1	-	3	493	c.284G>A	c.(283-285)CGG>CAG	p.R95Q	CCK_uc003cld.1_Missense_Mutation_p.R95Q	NM_000729	NP_000720	P06307	CCKN_HUMAN	cholecystokinin preproprotein	95					axonogenesis|eating behavior|neuron migration		neuropeptide hormone activity			central_nervous_system(1)	1		Ovarian(412;0.0728)		KIRC - Kidney renal clear cell carcinoma(284;0.219)														---	---	---	---
DNAH5	1767	broad.mit.edu	37	5	13793818	13793818	+	Missense_Mutation	SNP	C	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr5:13793818C>T	uc003jfd.2	-	49	8072	c.8030G>A	c.(8029-8031)CGA>CAA	p.R2677Q		NM_001369	NP_001360	Q8TE73	DYH5_HUMAN	dynein, axonemal, heavy chain 5	2677	AAA 3 (By similarity).				microtubule-based movement	cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			ovary(14)|skin(13)|upper_aerodigestive_tract(1)|central_nervous_system(1)|breast(1)|pancreas(1)	31	Lung NSC(4;0.00476)													Kartagener_syndrome				---	---	---	---
ATG12	9140	broad.mit.edu	37	5	115177189	115177189	+	Missense_Mutation	SNP	C	G	G			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr5:115177189C>G	uc003krh.2	-	1	311	c.202G>C	c.(202-204)GGA>CGA	p.G68R	AP3S1_uc003krl.2_5'Flank|AP3S1_uc003krk.2_5'Flank|AP3S1_uc003krm.2_5'Flank|ATG12_uc003kri.2_Missense_Mutation_p.G68R|ATG12_uc003krj.2_RNA	NM_004707	NP_004698	O94817	ATG12_HUMAN	APG12 autophagy 12-like	21					autophagic vacuole assembly|negative regulation of type I interferon production	pre-autophagosomal structure membrane	protein binding				0		all_cancers(142;0.00377)|all_epithelial(76;0.000129)|Prostate(80;0.0132)|Ovarian(225;0.0776)|Lung NSC(810;0.245)		OV - Ovarian serous cystadenocarcinoma(64;7.59e-08)|Epithelial(69;7.05e-07)|all cancers(49;3.11e-05)														---	---	---	---
AIM1	202	broad.mit.edu	37	6	106960219	106960219	+	Missense_Mutation	SNP	G	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr6:106960219G>T	uc003prh.2	+	1	490	c.3G>T	c.(1-3)ATG>ATT	p.M1I		NM_001624	NP_001615	Q9Y4K1	AIM1_HUMAN	absent in melanoma 1	1							sugar binding			breast(4)|ovary(2)|upper_aerodigestive_tract(1)|large_intestine(1)|skin(1)	9	Breast(9;0.0138)|all_epithelial(6;0.169)	all_cancers(87;4.67e-25)|all_epithelial(87;5.46e-21)|Acute lymphoblastic leukemia(125;2.15e-07)|all_hematologic(75;5.28e-06)|Colorectal(196;3.46e-05)|all_lung(197;5.94e-05)|Lung NSC(302;7.26e-05)|Ovarian(999;0.00473)	Epithelial(6;0.00114)|all cancers(7;0.00726)|BRCA - Breast invasive adenocarcinoma(8;0.0114)|OV - Ovarian serous cystadenocarcinoma(5;0.0305)	all cancers(137;1.73e-50)|Epithelial(106;2.42e-48)|OV - Ovarian serous cystadenocarcinoma(136;1.51e-27)|BRCA - Breast invasive adenocarcinoma(108;0.00104)|GBM - Glioblastoma multiforme(226;0.00858)														---	---	---	---
DOCK4	9732	broad.mit.edu	37	7	111381245	111381245	+	Nonsense_Mutation	SNP	G	A	A			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:111381245G>A	uc003vfx.2	-	46	5187	c.4918C>T	c.(4918-4920)CGA>TGA	p.R1640*	DOCK4_uc011kml.1_Nonsense_Mutation_p.R521*|DOCK4_uc011kmm.1_Nonsense_Mutation_p.R547*|DOCK4_uc003vfw.2_Nonsense_Mutation_p.R1090*|DOCK4_uc003vfy.2_Nonsense_Mutation_p.R1685*|DOCK4_uc003vfv.2_5'Flank	NM_014705	NP_055520	Q8N1I0	DOCK4_HUMAN	dedicator of cytokinesis 4	1640					cell chemotaxis	cytosol|endomembrane system|membrane|stereocilium	GTP binding|guanyl-nucleotide exchange factor activity|PDZ domain binding|Rac GTPase activator activity|Rac GTPase binding|receptor tyrosine kinase binding|SH3 domain binding			ovary(2)|haematopoietic_and_lymphoid_tissue(1)|central_nervous_system(1)	4		Acute lymphoblastic leukemia(1;0.0441)																---	---	---	---
ACCN3	9311	broad.mit.edu	37	7	150746220	150746220	+	Missense_Mutation	SNP	G	A	A			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr7:150746220G>A	uc003win.2	+	1	616	c.248G>A	c.(247-249)CGG>CAG	p.R83Q	ACCN3_uc003wio.2_Missense_Mutation_p.R83Q|ACCN3_uc003wip.2_Missense_Mutation_p.R83Q|ACCN3_uc003wiq.2_RNA	NM_004769	NP_004760	Q9UHC3	ACCN3_HUMAN	amiloride-sensitive cation channel 3 isoform a	83	Extracellular (Potential).				sensory perception|signal transduction	cytoplasm|integral to plasma membrane	ligand-gated sodium channel activity			ovary(1)|central_nervous_system(1)	2			OV - Ovarian serous cystadenocarcinoma(82;0.0121)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)														---	---	---	---
DLC1	10395	broad.mit.edu	37	8	12957206	12957206	+	Missense_Mutation	SNP	G	C	C			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr8:12957206G>C	uc003wwm.2	-	9	3084	c.2640C>G	c.(2638-2640)GAC>GAG	p.D880E	DLC1_uc003wwk.1_Missense_Mutation_p.D443E|DLC1_uc003wwl.1_Missense_Mutation_p.D477E|DLC1_uc011kxx.1_Missense_Mutation_p.D369E	NM_182643	NP_872584	Q96QB1	RHG07_HUMAN	deleted in liver cancer 1 isoform 1	880					actin cytoskeleton organization|activation of caspase activity|focal adhesion assembly|forebrain development|heart morphogenesis|hindbrain morphogenesis|induction of apoptosis|negative regulation of cell migration|negative regulation of cell proliferation|negative regulation of Rho protein signal transduction|negative regulation of stress fiber assembly|neural tube closure|positive regulation of protein dephosphorylation|regulation of cell shape|small GTPase mediated signal transduction	caveola|cytosol|focal adhesion|nucleus	Rho GTPase activator activity|SH2 domain binding			ovary(3)|pancreas(2)|lung(1)|kidney(1)	7																		---	---	---	---
TRIM55	84675	broad.mit.edu	37	8	67039497	67039497	+	5'UTR	SNP	C	A	A			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr8:67039497C>A	uc003xvv.2	+	1					TRIM55_uc003xvu.2_5'UTR|TRIM55_uc003xvw.2_5'UTR|TRIM55_uc003xvx.2_5'UTR	NM_184085	NP_908973			tripartite motif-containing 55 isoform 1							cytoplasm|microtubule|nucleus	signal transducer activity|zinc ion binding			skin(3)|ovary(1)|central_nervous_system(1)	5		Lung NSC(129;0.138)|all_lung(136;0.221)	Epithelial(68;0.0136)|all cancers(69;0.0582)|BRCA - Breast invasive adenocarcinoma(89;0.0628)|OV - Ovarian serous cystadenocarcinoma(28;0.0904)															---	---	---	---
MLLT3	4300	broad.mit.edu	37	9	20414343	20414343	+	Silent	SNP	A	G	G			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:20414343A>G	uc003zoe.2	-	5	760	c.501T>C	c.(499-501)AGT>AGC	p.S167S	MLLT3_uc011lne.1_Silent_p.S135S|MLLT3_uc011lnf.1_Silent_p.S164S|MLLT3_uc003zof.2_5'UTR|MLLT3_uc011lng.1_Missense_Mutation_p.V129A	NM_004529	NP_004520	P42568	AF9_HUMAN	myeloid/lymphoid or mixed-lineage leukemia	167	Poly-Ser.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	protein binding			lung(2)|ovary(1)	3				GBM - Glioblastoma multiforme(3;4.35e-105)|Lung(42;3.48e-06)|LUSC - Lung squamous cell carcinoma(42;7.92e-05)				T	MLL	ALL								---	---	---	---
NTNG2	84628	broad.mit.edu	37	9	135073844	135073844	+	Silent	SNP	G	A	A			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr9:135073844G>A	uc004cbh.2	+	3	1481	c.705G>A	c.(703-705)ACG>ACA	p.T235T		NM_032536	NP_115925	Q96CW9	NTNG2_HUMAN	netrin G2 precursor	235	Laminin N-terminal.				axonogenesis	anchored to plasma membrane					0				OV - Ovarian serous cystadenocarcinoma(145;1.23e-05)|Epithelial(140;0.000173)														---	---	---	---
SORCS1	114815	broad.mit.edu	37	10	108389086	108389086	+	Missense_Mutation	SNP	C	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr10:108389086C>T	uc001kym.2	-	19	2544	c.2536G>A	c.(2536-2538)GTC>ATC	p.V846I	SORCS1_uc001kyl.2_Missense_Mutation_p.V846I|SORCS1_uc009xxs.2_Missense_Mutation_p.V846I|SORCS1_uc001kyn.1_Missense_Mutation_p.V846I|SORCS1_uc001kyo.2_Missense_Mutation_p.V846I	NM_052918	NP_443150	Q8WY21	SORC1_HUMAN	SORCS receptor 1 isoform a	846	Lumenal (Potential).|PKD.					integral to membrane	neuropeptide receptor activity|protein binding			breast(1)|central_nervous_system(1)	2		Breast(234;0.0256)|Colorectal(252;0.09)|Lung NSC(174;0.168)		Epithelial(162;1.66e-05)|all cancers(201;0.000689)														---	---	---	---
CWF19L2	143884	broad.mit.edu	37	11	107288936	107288936	+	Missense_Mutation	SNP	T	C	C			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr11:107288936T>C	uc010rvp.1	-	9	1541	c.1511A>G	c.(1510-1512)GAG>GGG	p.E504G	CWF19L2_uc001pjh.3_RNA|CWF19L2_uc009yxo.2_RNA	NM_152434	NP_689647	Q2TBE0	C19L2_HUMAN	CWF19-like 2, cell cycle control	504	Potential.						catalytic activity				0		Melanoma(852;1.75e-05)|all_epithelial(67;6.27e-05)|Acute lymphoblastic leukemia(157;0.000967)|all_hematologic(158;0.0017)|Breast(348;0.0258)		Epithelial(105;7.18e-06)|BRCA - Breast invasive adenocarcinoma(274;1.65e-05)|all cancers(92;1.76e-05)														---	---	---	---
DCLK1	9201	broad.mit.edu	37	13	36396972	36396972	+	Missense_Mutation	SNP	T	C	C			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr13:36396972T>C	uc001uvf.2	-	11	1681	c.1448A>G	c.(1447-1449)TAC>TGC	p.Y483C	DCLK1_uc001uve.3_Missense_Mutation_p.Y176C|DCLK1_uc010teh.1_Missense_Mutation_p.Y176C|DCLK1_uc010abk.2_Intron	NM_004734	NP_004725	O15075	DCLK1_HUMAN	doublecortin-like kinase 1	483	Protein kinase.				cell differentiation|central nervous system development|endosome transport|intracellular signal transduction|response to virus	integral to plasma membrane	ATP binding|protein serine/threonine kinase activity|receptor signaling protein activity			stomach(6)|ovary(2)|skin(1)	9		Breast(139;0.0147)|Lung SC(185;0.0685)|Prostate(109;0.122)	KIRC - Kidney renal clear cell carcinoma(5;0.119)|Kidney(79;0.169)	all cancers(112;1.72e-06)|Epithelial(112;4.24e-05)|BRCA - Breast invasive adenocarcinoma(63;0.00159)|OV - Ovarian serous cystadenocarcinoma(117;0.0158)|GBM - Glioblastoma multiforme(144;0.0638)														---	---	---	---
DIAPH3	81624	broad.mit.edu	37	13	60453471	60453471	+	Missense_Mutation	SNP	G	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr13:60453471G>T	uc001vht.2	-	21	2718	c.2499C>A	c.(2497-2499)AGC>AGA	p.S833R	DIAPH3_uc001vhu.2_Missense_Mutation_p.S570R|DIAPH3_uc001vhv.2_Missense_Mutation_p.S411R	NM_001042517	NP_001035982	Q9NSV4	DIAP3_HUMAN	diaphanous homolog 3 isoform a	833	FH2.				actin cytoskeleton organization		actin binding|Rho GTPase binding			ovary(2)	2		Breast(118;0.052)|Prostate(109;0.103)|Hepatocellular(98;0.132)		GBM - Glioblastoma multiforme(99;2.77e-05)														---	---	---	---
TUBG2	27175	broad.mit.edu	37	17	40817732	40817732	+	Missense_Mutation	SNP	C	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr17:40817732C>T	uc010wgr.1	+	8	986	c.730C>T	c.(730-732)CGC>TGC	p.R244C	TUBG2_uc002iaq.2_Missense_Mutation_p.R86C|TUBG2_uc002iar.2_Missense_Mutation_p.R91C|TUBG2_uc002ias.2_Missense_Mutation_p.R86C|TUBG2_uc002iap.2_Missense_Mutation_p.R91C	NM_016437	NP_057521	Q9NRH3	TBG2_HUMAN	tubulin, gamma 2	244					G2/M transition of mitotic cell cycle|microtubule-based process|protein polymerization	cytosol	GTP binding|GTPase activity|structural molecule activity			ovary(1)	1		Breast(137;0.00116)		BRCA - Breast invasive adenocarcinoma(366;0.141)														---	---	---	---
C3	718	broad.mit.edu	37	19	6693046	6693046	+	Silent	SNP	G	A	A			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chr19:6693046G>A	uc002mfm.2	-	26	3341	c.3279C>T	c.(3277-3279)ATC>ATT	p.I1093I	C3_uc002mfl.2_5'UTR	NM_000064	NP_000055	P01024	CO3_HUMAN	complement component 3 precursor	1093					complement activation, alternative pathway|complement activation, classical pathway|G-protein coupled receptor protein signaling pathway|inflammatory response|positive regulation vascular endothelial growth factor production	extracellular space	endopeptidase inhibitor activity|receptor binding			skin(3)|ovary(1)|pancreas(1)	5				GBM - Glioblastoma multiforme(1328;1.36e-05)|Lung(535;0.00661)														---	---	---	---
MAGEC2	51438	broad.mit.edu	37	X	141291626	141291626	+	Missense_Mutation	SNP	A	T	T			TCGA-CG-5716-01	TCGA-CG-5716-01									Somatic	Phase_I	Capture				Illumina GAIIx	g.chrX:141291626A>T	uc004fbu.1	-	3	496	c.148T>A	c.(148-150)TTT>ATT	p.F50I		NM_016249	NP_057333	Q9UBF1	MAGC2_HUMAN	melanoma antigen family C, 2	50	Ser-rich.					cytoplasm|nucleus				breast(2)	2	Acute lymphoblastic leukemia(192;6.56e-05)														HNSCC(46;0.14)			---	---	---	---
