Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Genome_Change	Annotation_Transcript	Transcript_Strand	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	i_TCGAscape_Amplification_Peaks	i_TCGAscape_Deletion_Peaks	DrugBank	i_ACHILLES_Top_Genes	i_CCLE_ONCOMAP_overlapping_mutations	i_CCLE_ONCOMAP_total_mutations_in_gene	i_CCLE_SEQ_overlapping_mutations	i_CCLE_SEQ_total_mutations_in_gene	MUTSIG_Significant_Genes	OREGANNO_ID	OREGANNO_Values	i_tumor_f	i_init_t_lod	i_t_lod_fstar	i_t_alt_count	i_t_ref_count	i_normal_best_gt	i_failure_reasons	i_judgement	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	dataset	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	type	classification	start	end	gene	chr	ref_allele	tum_allele1	tum_allele2	context_orig	context65	gene_name	newbase	categ	categ_ignoring_null_categ
PCDH15	65217	broad.mit.edu	36	10	55261173	55261173	+	Silent	SNP	T	C	C			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr10:55261173T>C	uc001jju.1	-	c.4110A>G	c.(4108-4110)CTA>CTG	p.L1370L	PCDH15_uc001jjv.1_Intron	NM_033056	NP_149045	Q96QU1	PCD15_HUMAN	protocadherin 15 isoform CD1-4 precursor	1370	Extracellular (Potential).				equilibrioception|homophilic cell adhesion|photoreceptor cell maintenance|response to stimulus|sensory perception of sound	extracellular region|extracellular space|integral to membrane|photoreceptor outer segment|plasma membrane|stereocilium|synapse	calcium ion binding			pancreas(5)|ovary(4)	9		Melanoma(3;0.117)|Lung SC(717;0.238)								1612				0.164179	53.078773	67.416017	22	112	TT		KEEP	---	---	---	---	capture			Silent	SNP	55261173	55261173	11931	10	T	C	C	53	53	PCDH15	C	4	4
OR11G2	390439	broad.mit.edu	36	14	19735933	19735933	+	Missense_Mutation	SNP	A	G	G			TCGA-26-5133-01	TCGA-26-5133-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr14:19735933A>G	uc001vwq.1	+	c.599A>G	c.(598-600)AAC>AGC	p.N200S		NM_001005503	NP_001005503	Q8NGC1	O11G2_HUMAN	olfactory receptor, family 11, subfamily G,	200	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)	1	all_cancers(95;0.00108)													0.120482	17.292172	29.012594	10	73	AA		KEEP	---	---	---	---	capture	Epithelial(56;9.76e-07)|all cancers(55;5.61e-06)	GBM - Glioblastoma multiforme(265;0.0144)	Missense_Mutation	SNP	19735933	19735933	11331	14	A	G	G	2	2	OR11G2	G	4	4
AKAP5	9495	broad.mit.edu	36	14	64006084	64006084	+	Missense_Mutation	SNP	T	C	C			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr14:64006084T>C	uc001xhd.2	+	c.1219T>C	c.(1219-1221)TCA>CCA	p.S407P	ZBTB25_uc001xhc.2_Intron|AKAP5_uc001xhe.2_Missense_Mutation_p.S407P	NM_004857	NP_004848	P24588	AKAP5_HUMAN	A-kinase anchor protein 5	407				S -> Y (in Ref. 3).	energy reserve metabolic process|positive regulation of cAMP biosynthetic process|positive regulation of protein kinase A signaling cascade|protein targeting|regulation of insulin secretion|signal transduction|synaptic transmission	cytosol	adenylate cyclase binding|calmodulin binding				0														0.116667	32.846002	58.866743	21	159	TT		KEEP	---	---	---	---	capture		all cancers(60;0.00749)|OV - Ovarian serous cystadenocarcinoma(108;0.0095)|BRCA - Breast invasive adenocarcinoma(234;0.0449)	Missense_Mutation	SNP	64006084	64006084	457	14	T	C	C	58	58	AKAP5	C	4	4
LTBP2	4053	broad.mit.edu	36	14	74044524	74044524	+	Missense_Mutation	SNP	G	A	A			TCGA-26-5133-01	TCGA-26-5133-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr14:74044524G>A	uc001xqa.1	-	c.3680C>T	c.(3679-3681)CCG>CTG	p.P1227L		NM_000428	NP_000419	Q14767	LTBP2_HUMAN	latent transforming growth factor beta binding	1227	EGF-like 13; calcium-binding (Potential).|Cys-rich.				protein secretion|protein targeting|transforming growth factor beta receptor signaling pathway	extracellular space|proteinaceous extracellular matrix	calcium ion binding|growth factor binding			liver(1)	1														0.7	139.870555	142.016086	42	18	GG		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(234;0.00219)|READ - Rectum adenocarcinoma(1;0.0649)	Missense_Mutation	SNP	74044524	74044524	9450	14	G	A	A	39	39	LTBP2	A	1	1
ATP8B4	79895	broad.mit.edu	36	15	47977711	47977711	+	Missense_Mutation	SNP	A	T	T			TCGA-26-5133-01	TCGA-26-5133-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr15:47977711A>T	uc001zxu.1	-	c.2319T>A	c.(2317-2319)AAT>AAA	p.N773K	ATP8B4_uc010ber.1_Missense_Mutation_p.N646K|ATP8B4_uc001zxv.1_Missense_Mutation_p.N71K	NM_024837	NP_079113	Q8TF62	AT8B4_HUMAN	ATPase class I type 8B member 4	773	Cytoplasmic (Potential).				ATP biosynthetic process	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			ovary(2)|breast(2)|large_intestine(1)	5		all_lung(180;0.00183)												0.430769	91.494389	91.765135	28	37	AA		KEEP	---	---	---	---	capture		all cancers(107;2.41e-07)|GBM - Glioblastoma multiforme(94;8.28e-05)	Missense_Mutation	SNP	47977711	47977711	1216	15	A	T	T	8	8	ATP8B4	T	4	4
TPSD1	23430	broad.mit.edu	36	16	1247051	1247051	+	Silent	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr16:1247051C>T	uc002clb.1	+	c.507C>T	c.(505-507)GAC>GAT	p.D169D	TPSD1_uc010brm.1_Silent_p.D98D	NM_012217	NP_036349	Q9BZJ3	TRYD_HUMAN	tryptase delta 1	169	Peptidase S1.				proteolysis	extracellular region	serine-type endopeptidase activity				0		Hepatocellular(780;0.00369)												0.148148	6.501384	9.694666	4	23	CC		KEEP	---	---	---	---	capture			Silent	SNP	1247051	1247051	16969	16	C	T	T	19	19	TPSD1	T	1	1
TP53	7157	broad.mit.edu	36	17	7518305	7518305	+	Missense_Mutation	SNP	T	C	C			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr17:7518305T>C	uc002gim.2	-	c.701A>G	c.(700-702)TAC>TGC	p.Y234C	TP53_uc002gig.1_Missense_Mutation_p.Y234C|TP53_uc002gih.1_Missense_Mutation_p.Y234C|TP53_uc010cne.1_5'Flank|TP53_uc010cnf.1_Missense_Mutation_p.Y102C|TP53_uc010cng.1_Missense_Mutation_p.Y102C|TP53_uc002gii.1_Missense_Mutation_p.Y102C|TP53_uc010cnh.1_Missense_Mutation_p.Y234C|TP53_uc010cni.1_Missense_Mutation_p.Y234C|TP53_uc002gij.2_Missense_Mutation_p.Y234C|TP53_uc010cnj.1_Non-coding_Transcript|TP53_uc002gin.2_Missense_Mutation_p.Y141C|TP53_uc002gio.2_Missense_Mutation_p.Y102C	NM_001126112	NP_001119584	P04637	P53_HUMAN	tumor protein p53 isoform a	234	Required for interaction with FBXO42.||Interaction with HIPK1 (By similarity).|Interaction with AXIN1 (By similarity).		Y -> F (in a sporadic cancer; somatic mutation).|Y -> K (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions).|Y -> N (in sporadic cancers; somatic mutation).|Y -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation).|Y -> S (in sporadic cancers; somatic mutation).|Y -> H (in sporadic cancers; somatic mutation).|Y -> D (in sporadic cancers; somatic mutation).|Y -> Q (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	chromatin|cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|promoter binding|promoter binding|protease binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|sequence-specific DNA binding transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|ubiquitin protein ligase binding|zinc ion binding	p.Y234C(69)|p.0?(6)|p.Y234S(3)|p.Y234del(3)|p.I232_Y236delIHYNY(1)|p.Y234fs*2(1)|p.Y234F(1)|p.T230_Y234delTTIHY(1)|p.C141fs*29(1)|p.H233fs*6(1)|p.V225fs*23(1)|p.D228fs*12(1)|p.Y234fs*5(1)|p.Y234fs*4(1)|p.I232fs*5(1)|p.H233_C242del10(1)		large_intestine(4614)|breast(2344)|upper_aerodigestive_tract(2150)|lung(1958)|ovary(1559)|oesophagus(1462)|haematopoietic_and_lymphoid_tissue(1212)|stomach(1127)|urinary_tract(1113)|central_nervous_system(1072)|liver(805)|skin(693)|pancreas(370)|biliary_tract(247)|soft_tissue(209)|prostate(192)|endometrium(150)|bone(102)|vulva(79)|kidney(79)|cervix(68)|thyroid(54)|salivary_gland(41)|adrenal_gland(37)|peritoneum(33)|eye(24)|thymus(21)|genital_tract(16)|autonomic_ganglia(16)|small_intestine(14)|testis(11)|penis(10)|vagina(6)|meninges(5)|pituitary(4)|pleura(3)|gastrointestinal_tract_(site_indeterminate)(1)|NS(1)|Fallopian tube(1)|placenta(1)	21904		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)				Pancreas(47;798 1329 9957 10801)		111	p.I232fs(HDMYZ-Tumor)	690	TCGA GBM(1;<1E-8)|TSP Lung(2;<1E-8)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			0.843137	169.562256	175.295618	43	8	TT		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)	Missense_Mutation	SNP	7518305	7518305	16923	17	T	C	C	57	57	TP53	C	4	4
WRAP53	55135	broad.mit.edu	36	17	7545820	7545820	+	Missense_Mutation	SNP	C	G	G			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr17:7545820C>G	uc002gip.1	+	c.943C>G	c.(943-945)CGA>GGA	p.R315G	WRAP53_uc002giq.1_Non-coding_Transcript|WRAP53_uc002gir.1_Missense_Mutation_p.R315G|WRAP53_uc010cnl.1_Missense_Mutation_p.R282G	NM_018081	NP_060551	Q9BUR4	WAP53_HUMAN	WD repeat domain 79	315					positive regulation of telomerase activity|telomere formation via telomerase	Cajal body|cytoplasm|telomerase holoenzyme complex	protein binding|RNA binding				0														0.333333	8.259648	8.633891	5	10	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	7545820	7545820	17974	17	C	G	G	23	23	WRAP53	G	3	3
PLEKHG2	64857	broad.mit.edu	36	19	44607699	44607699	+	Silent	SNP	T	G	G			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr19:44607699T>G	uc002oli.2	+	c.3960T>G	c.(3958-3960)GCT>GCG	p.A1320A	PLEKHG2_uc002olj.2_Intron|PLEKHG2_uc010ego.1_Silent_p.A1291A	NM_022835	NP_073746	Q9H7P9	PKHG2_HUMAN	common-site lymphoma/leukemia guanine nucleotide	1362					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol	Rho guanyl-nucleotide exchange factor activity			pancreas(1)|breast(1)|skin(1)	3	all_cancers(60;3.08e-07)|all_lung(34;2.66e-08)|Lung NSC(34;3e-08)|all_epithelial(25;6.57e-07)|Ovarian(47;0.0569)													0.102804	7.951495	24.768572	11	96	TT		KEEP	---	---	---	---	capture	Epithelial(26;2.92e-26)|all cancers(26;2.01e-23)|Lung(45;0.000499)|LUSC - Lung squamous cell carcinoma(53;0.000657)		Silent	SNP	44607699	44607699	12495	19	T	G	G	54	54	PLEKHG2	G	4	4
GON4L	54856	broad.mit.edu	36	1	154002525	154002525	+	Missense_Mutation	SNP	C	G	G			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:154002525C>G	uc001flz.2	-	c.3363G>C	c.(3361-3363)AAG>AAC	p.K1121N	GON4L_uc001fly.1_Missense_Mutation_p.K1121N|GON4L_uc009wrh.1_Missense_Mutation_p.K1121N|GON4L_uc001fma.1_Missense_Mutation_p.K1121N|GON4L_uc001fmb.2_Missense_Mutation_p.K317N|GON4L_uc001fmc.1_Missense_Mutation_p.K1121N|GON4L_uc001fmd.2_Missense_Mutation_p.K1121N|GON4L_uc009wri.1_Missense_Mutation_p.K707N|GON4L_uc009wrg.1_Non-coding_Transcript	NM_001037533	NP_001032622	Q3T8J9	GON4L_HUMAN	gon-4-like isoform a	1121					regulation of transcription, DNA-dependent	cytoplasm|nucleus	DNA binding			ovary(3)	3	Hepatocellular(266;0.0997)|all_hematologic(923;0.145)|all_neural(408;0.195)													0.265734	331.534538	352.82443	114	315	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	154002525	154002525	6845	1	C	G	G	32	32	GON4L	G	3	3
C1orf69	200205	broad.mit.edu	36	1	226429454	226429454	+	Missense_Mutation	SNP	G	A	A			TCGA-26-5133-01	TCGA-26-5133-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:226429454G>A	uc001hsl.2	+	c.688G>A	c.(688-690)GAG>AAG	p.E230K		NM_001010867	NP_001010867	Q5T440	CAF17_HUMAN	hypothetical protein LOC200205	230					glycine catabolic process|heme biosynthetic process	mitochondrion	aminomethyltransferase activity				0		Prostate(94;0.0405)												0.875	173.421812	182.206707	56	8	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	226429454	226429454	2132	1	G	A	A	45	45	C1orf69	A	2	2
MUTYH	4595	broad.mit.edu	36	1	45570052	45570052	+	Missense_Mutation	SNP	T	A	A			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr1:45570052T>A	uc009vxp.1	-	c.1054A>T	c.(1054-1056)ACC>TCC	p.T352S	MUTYH_uc009vxn.1_Missense_Mutation_p.T174S|MUTYH_uc001cnf.1_Missense_Mutation_p.T324S|MUTYH_uc009vxo.1_Missense_Mutation_p.T324S|MUTYH_uc001cng.1_Missense_Mutation_p.T335S|MUTYH_uc001cnj.1_Missense_Mutation_p.T232S|MUTYH_uc001cni.1_Missense_Mutation_p.T324S|MUTYH_uc001cnh.1_Missense_Mutation_p.T325S|MUTYH_uc001cnm.1_Missense_Mutation_p.T349S|MUTYH_uc001cno.1_Missense_Mutation_p.T232S|MUTYH_uc001cnk.1_Missense_Mutation_p.T209S|MUTYH_uc001cnl.1_Missense_Mutation_p.T338S|MUTYH_uc001cnn.1_Missense_Mutation_p.T339S	NM_001128425	NP_001121897	Q9UIF7	MUTYH_HUMAN	mutY homolog isoform 5	349					depurination|mismatch repair	nucleoplasm	4 iron, 4 sulfur cluster binding|DNA N-glycosylase activity|endonuclease activity|metal ion binding|MutSalpha complex binding				0	Acute lymphoblastic leukemia(166;0.155)									162				0.425532	55.186288	55.414567	20	27	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	45570052	45570052	10387	1	T	A	A	58	58	MUTYH	A	4	4
GREB1	9687	broad.mit.edu	36	2	11668373	11668373	+	Silent	SNP	G	A	A			TCGA-26-5133-01	TCGA-26-5133-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr2:11668373G>A	uc002rbk.1	+	c.2775G>A	c.(2773-2775)TCG>TCA	p.S925S	GREB1_uc002rbo.1_Silent_p.S559S|GREB1_uc002rbp.1_5'Flank	NM_014668	NP_055483	Q4ZG55	GREB1_HUMAN	GREB1 protein isoform a	925						integral to membrane				ovary(1)	1	all_hematologic(175;0.127)|Acute lymphoblastic leukemia(172;0.155)					Ovarian(39;850 945 2785 23371 33093)								0.515152	267.327148	267.363093	85	80	GG		KEEP	---	---	---	---	capture		Epithelial(75;0.115)|OV - Ovarian serous cystadenocarcinoma(76;0.186)	Silent	SNP	11668373	11668373	7037	2	G	A	A	39	39	GREB1	A	1	1
FMNL2	114793	broad.mit.edu	36	2	153107562	153107562	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:153107562C>T	uc002tye.1	+	c.265C>T	c.(265-267)CCA>TCA	p.P89S		NM_052905	NP_443137	Q96PY5	FMNL2_HUMAN	formin-like 2	89	GBD/FH3.				actin cytoskeleton organization	cytoplasm	actin binding|Rho GTPase binding			central_nervous_system(2)|ovary(1)	3														0.337748	142.765148	146.287224	51	100	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	153107562	153107562	6194	2	C	T	T	30	30	FMNL2	T	2	2
ACVR1C	130399	broad.mit.edu	36	2	158193393	158193393	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:158193393C>T	uc002tzk.2	-	c.10G>A	c.(10-12)GCG>ACG	p.A4T	ACVR1C_uc002tzl.2_Missense_Mutation_p.A4T|ACVR1C_uc010fof.1_Missense_Mutation_p.A4T	NM_145259	NP_001104501	Q8NER5	ACV1C_HUMAN	activin receptor-like kinase 7 isoform 1	4					apoptosis|cell differentiation|protein phosphorylation|regulation of apoptosis	activin receptor complex	activin receptor activity, type I|ATP binding|metal ion binding|transforming growth factor beta receptor activity			ovary(2)|lung(2)	4										127				0.444444	9.205186	9.22775	4	5	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	158193393	158193393	223	2	C	T	T	26	26	ACVR1C	T	2	2
APOB	338	broad.mit.edu	36	2	21079268	21079268	+	Silent	SNP	T	C	C			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr2:21079268T>C	uc002red.1	-	c.12531A>G	c.(12529-12531)CGA>CGG	p.R4177R		NM_000384	NP_000375	P04114	APOB_HUMAN	apolipoprotein B precursor	4177					cholesterol homeostasis|cholesterol metabolic process|leukocyte migration|low-density lipoprotein particle clearance|low-density lipoprotein particle remodeling|platelet activation|positive regulation of cholesterol storage|positive regulation of macrophage derived foam cell differentiation|receptor-mediated endocytosis|response to virus|very-low-density lipoprotein particle assembly	chylomicron remnant|clathrin-coated endocytic vesicle membrane|endoplasmic reticulum lumen|endoplasmic reticulum membrane|endosome lumen|endosome membrane|intermediate-density lipoprotein particle|low-density lipoprotein particle|mature chylomicron|microsome|plasma membrane|very-low-density lipoprotein particle	cholesterol transporter activity|enzyme binding|heparin binding|low-density lipoprotein particle receptor binding|phospholipid binding|protein heterodimerization activity			ovary(11)|central_nervous_system(3)|large_intestine(2)|pancreas(1)|skin(1)	18	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)				Atorvastatin(DB01076)									0.36478	191.913557	194.468234	58	101	TT		KEEP	---	---	---	---	capture			Silent	SNP	21079268	21079268	796	2	T	C	C	54	54	APOB	C	4	4
TMEM18	129787	broad.mit.edu	36	2	659581	659581	+	Silent	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:659581C>T	uc002qwl.1	-	c.422G>A	c.(421-423)TGA>TAA	p.*141*	TMEM18_uc002qwk.1_Non-coding_Transcript	NM_152834	NP_690047	Q96B42	TMM18_HUMAN	transmembrane protein 18	141					cell migration	integral to membrane|nuclear membrane				ovary(1)	1	all_hematologic(175;0.0429)|Acute lymphoblastic leukemia(172;0.0627)	all_cancers(51;5.27e-05)|all_epithelial(98;2.11e-06)|Ovarian(717;0.0253)												0.577143	298.564765	299.467984	101	74	CC		KEEP	---	---	---	---	capture		all cancers(51;1.95e-21)|Epithelial(75;9.47e-21)|OV - Ovarian serous cystadenocarcinoma(76;8.15e-18)|GBM - Glioblastoma multiforme(21;0.0285)	Silent	SNP	659581	659581	16632	2	C	T	T	29	29	TMEM18	T	2	2
SR140	23350	broad.mit.edu	36	3	144213808	144213808	+	Missense_Mutation	SNP	A	G	G			TCGA-26-5133-01	TCGA-26-5133-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr3:144213808A>G	uc003evh.1	+	c.145A>G	c.(145-147)AGC>GGC	p.S49G	SR140_uc003evi.1_5'UTR|SR140_uc003evj.1_Non-coding_Transcript|SR140_uc003evk.1_Missense_Mutation_p.S49G	NM_001080415	NP_001073884	O15042	SR140_HUMAN	U2-associated SR140 protein	49					RNA processing	nucleus	nucleotide binding|RNA binding				0						Colon(87;897 1320 15089 19747 35974)								0.471429	119.776851	119.826003	33	37	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	144213808	144213808	15645	3	A	G	G	11	11	SR140	G	4	4
CX3CR1	1524	broad.mit.edu	36	3	39282962	39282962	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr3:39282962C>T	uc003cjl.1	-	c.43G>A	c.(43-45)GAT>AAT	p.D15N	CX3CR1_uc010hhq.1_Missense_Mutation_p.D15N	NM_001337	NP_001328	P49238	CX3C1_HUMAN	chemokine (C-X3-C motif) receptor 1	15	Extracellular (Potential).				cell adhesion|cellular defense response|chemotaxis|interspecies interaction between organisms|response to wounding	integral to plasma membrane	chemokine receptor activity				0														0.308642	67.644239	70.287958	25	56	CC		KEEP	---	---	---	---	capture		KIRC - Kidney renal clear cell carcinoma(284;0.0557)|Kidney(284;0.0699)	Missense_Mutation	SNP	39282962	39282962	4235	3	C	T	T	31	31	CX3CR1	T	1	1
C3orf18	51161	broad.mit.edu	36	3	50578101	50578101	+	Missense_Mutation	SNP	A	C	C			TCGA-26-5133-01	TCGA-26-5133-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr3:50578101A>C	uc003dar.1	-	c.34T>G	c.(34-36)TTC>GTC	p.F12V	C3orf18_uc010hln.1_Intron|C3orf18_uc003das.1_Missense_Mutation_p.F12V|C3orf18_uc010hlo.1_Missense_Mutation_p.F12V|C3orf18_uc010hlp.1_Intron|C3orf18_uc003dat.1_Missense_Mutation_p.F12V	NM_016210	NP_057294	Q9UK00	CC018_HUMAN	hypothetical protein LOC51161	12						integral to membrane				pancreas(1)	1														0.611111	16.831068	16.988221	11	7	AA		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(193;0.000278)|KIRC - Kidney renal clear cell carcinoma(197;0.0175)|Kidney(197;0.0207)	Missense_Mutation	SNP	50578101	50578101	2304	3	A	C	C	2	2	C3orf18	C	4	4
BAP1	8314	broad.mit.edu	36	3	52417558	52417558	+	Missense_Mutation	SNP	A	G	G			TCGA-26-5133-01	TCGA-26-5133-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr3:52417558A>G	uc003ddx.1	-	c.227T>C	c.(226-228)ATT>ACT	p.I76T	PHF7_uc003ddy.1_5'Flank|PHF7_uc003ddz.1_5'Flank	NM_004656	NP_004647	Q92560	BAP1_HUMAN	BRCA1 associated protein-1	76					monoubiquitinated histone H2A deubiquitination|negative regulation of cell proliferation|protein K48-linked deubiquitination|regulation of cell cycle|regulation of cell growth|ubiquitin-dependent protein catabolic process	cytoplasm|nucleolus|PR-DUB complex	chromatin binding|protein binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity			eye(28)|lung(2)|ovary(1)|breast(1)	32						GBM(101;493 1458 7992 21037 25532)				294				0.171429	13.929032	17.500002	6	29	AA		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(193;1.72e-05)|Kidney(197;0.0018)|KIRC - Kidney renal clear cell carcinoma(197;0.00203)|OV - Ovarian serous cystadenocarcinoma(275;0.0277)	Missense_Mutation	SNP	52417558	52417558	1332	3	A	G	G	4	4	BAP1	G	4	4
ATXN7	6314	broad.mit.edu	36	3	63873512	63873512	+	Silent	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr3:63873512C>T	uc010hnv.1	+	c.198C>T	c.(196-198)GGC>GGT	p.G66G	ATXN7_uc003dlw.2_Silent_p.G66G|ATXN7_uc010hnu.1_Silent_p.G66G|ATXN7_uc003dlv.2_Silent_p.G66G	NM_001128149	NP_001121621	O15265	ATX7_HUMAN	ataxin 7 isoform b	66					cell death|histone deubiquitination|nucleus organization|regulation of transcription, DNA-dependent|transcription, DNA-dependent|visual perception	cytoplasm|nuclear matrix|nucleolus	protein binding|zinc ion binding				0		Prostate(884;0.0181)												0.55	57.760358	57.850662	22	18	CC		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(55;0.000614)|KIRC - Kidney renal clear cell carcinoma(15;0.00294)|Kidney(15;0.00305)	Silent	SNP	63873512	63873512	1235	3	C	T	T	27	27	ATXN7	T	1	1
KIAA0232	9778	broad.mit.edu	36	4	6916593	6916593	+	Nonsense_Mutation	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr4:6916593C>T	uc003gjr.2	+	c.3583C>T	c.(3583-3585)CAG>TAG	p.Q1195*	KIAA0232_uc003gjq.2_Nonsense_Mutation_p.Q1195*	NM_014743	NP_055558	Q92628	K0232_HUMAN	hypothetical protein LOC9778	1195							ATP binding			ovary(2)	2														0.483146	131.416458	131.438656	43	46	CC		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	6916593	6916593	8470	4	C	T	T	21	21	KIAA0232	T	5	2
NAAA	27163	broad.mit.edu	36	4	77061147	77061147	+	Missense_Mutation	SNP	G	C	C			TCGA-26-5133-01	TCGA-26-5133-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr4:77061147G>C	uc003hjb.1	-	c.820C>G	c.(820-822)CTA>GTA	p.L274V	NAAA_uc003hja.1_Missense_Mutation_p.L274V|NAAA_uc003hjc.2_Missense_Mutation_p.L274V|NAAA_uc003hjd.2_Non-coding_Transcript	NM_014435	NP_055250	Q02083	NAAA_HUMAN	N-acylethanolamine acid amidase isoform 1	274					lipid metabolic process	lysosome	hydrolase activity				0														0.393701	169.223852	170.480084	50	77	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	77061147	77061147	10522	4	G	C	C	33	33	NAAA	C	3	3
C6orf10	10665	broad.mit.edu	36	6	32368923	32368923	+	Missense_Mutation	SNP	T	A	A			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr6:32368923T>A	uc003obe.1	-	c.1505A>T	c.(1504-1506)GAA>GTA	p.E502V	C6orf10_uc003obf.1_Missense_Mutation_p.E500V|C6orf10_uc010jtx.1_Missense_Mutation_p.E500V	NM_006781	NP_006772	Q5SRN2	CF010_HUMAN	chromosome 6 open reading frame 10	502	Lys-rich.					integral to membrane					0														0.475113	297.027011	297.147767	105	116	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	32368923	32368923	2418	6	T	A	A	62	62	C6orf10	A	4	4
HLA-DMB	3109	broad.mit.edu	36	6	33011297	33011297	+	Missense_Mutation	SNP	G	A	A			TCGA-26-5133-01	TCGA-26-5133-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr6:33011297G>A	uc003ocl.1	-	c.733C>T	c.(733-735)CAC>TAC	p.H245Y	HLA-DMB_uc003ocj.1_3'UTR|HLA-DMB_uc003ock.1_Non-coding_Transcript|HLA-DMB_uc010jud.1_Missense_Mutation_p.H114Y|HLA-DMB_uc010jue.1_Intron|HLA-DMB_uc010juf.1_Intron	NM_002118	NP_002109	P28068	DMB_HUMAN	major histocompatibility complex, class II, DM	245	Cytoplasmic (Potential).				antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|interferon-gamma-mediated signaling pathway|T cell costimulation|T cell receptor signaling pathway	integral to membrane|late endosome membrane|lysosomal membrane|MHC class II protein complex					0														0.386243	209.627297	211.771843	73	116	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	33011297	33011297	7490	6	G	A	A	47	47	HLA-DMB	A	2	2
GRM4	2914	broad.mit.edu	36	6	34112095	34112095	+	Silent	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr6:34112095C>T	uc003oir.2	-	c.1770G>A	c.(1768-1770)CTG>CTA	p.L590L	GRM4_uc010jvh.1_Silent_p.L590L|GRM4_uc010jvi.1_Silent_p.L282L|GRM4_uc010jvj.1_Silent_p.L474L|GRM4_uc003oio.1_Silent_p.L282L|GRM4_uc003oip.1_Non-coding_Transcript|GRM4_uc003oiq.1_Silent_p.L457L	NM_000841	NP_000832	Q14833	GRM4_HUMAN	glutamate receptor, metabotropic 4	590	Helical; Name=1; (Potential).				activation of MAPK activity|inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway|neuroprotection|neurotransmitter secretion|positive regulation of MAPKKK cascade	cytoplasmic vesicle|integral to plasma membrane	G-protein coupled receptor activity|glutamate receptor activity			ovary(1)	1					L-Glutamic Acid(DB00142)									0.271739	49.24239	53.575914	25	67	CC		KEEP	---	---	---	---	capture			Silent	SNP	34112095	34112095	7078	6	C	T	T	25	25	GRM4	T	2	2
MCM3	4172	broad.mit.edu	36	6	52257429	52257429	+	Missense_Mutation	SNP	C	G	G			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr6:52257429C>G	uc003pan.1	-	c.3G>C	c.(1-3)ATG>ATC	p.M1I		NM_002388	NP_002379	P25205	MCM3_HUMAN	minichromosome maintenance complex component 3	1					cell cycle checkpoint|DNA strand elongation involved in DNA replication|DNA-dependent DNA replication initiation|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle|S phase of mitotic cell cycle	alpha DNA polymerase:primase complex|centrosome|MCM complex|perinuclear region of cytoplasm	ATP binding|DNA binding|helicase activity|protein binding			ovary(1)|lung(1)|skin(1)	3	Lung NSC(77;0.0931)													0.291667	20.215086	21.148211	7	17	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	52257429	52257429	9776	6	C	G	G	21	21	MCM3	G	3	3
SNTB1	6641	broad.mit.edu	36	8	121714044	121714044	+	Missense_Mutation	SNP	T	C	C			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr8:121714044T>C	uc010mdg.1	-	c.817A>G	c.(817-819)AAG>GAG	p.K273E	SNTB1_uc003ypd.1_Missense_Mutation_p.K273E|SNTB1_uc003ype.2_Missense_Mutation_p.K273E	NM_021021	NP_066301	Q13884	SNTB1_HUMAN	basic beta 1 syntrophin	273	PH 1.				muscle contraction	cell junction|cytoplasm|cytoskeleton|dystrophin-associated glycoprotein complex|sarcolemma	actin binding|calmodulin binding			skin(3)	3	Lung NSC(37;4.46e-09)|Ovarian(258;0.0254)|Hepatocellular(40;0.0997)													0.461538	149.757413	149.872496	42	49	TT		KEEP	---	---	---	---	capture	STAD - Stomach adenocarcinoma(47;0.00503)		Missense_Mutation	SNP	121714044	121714044	15372	8	T	C	C	61	61	SNTB1	C	4	4
SH2D3C	10044	broad.mit.edu	36	9	129547182	129547182	+	Missense_Mutation	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr9:129547182C>T	uc004bsc.1	-	c.1282G>A	c.(1282-1284)GCC>ACC	p.A428T	SH2D3C_uc010mxo.1_Missense_Mutation_p.A268T|SH2D3C_uc004bry.1_Missense_Mutation_p.A270T|SH2D3C_uc004brz.2_Missense_Mutation_p.A67T|SH2D3C_uc004bsb.1_Missense_Mutation_p.A360T|SH2D3C_uc004bsa.1_Missense_Mutation_p.A271T	NM_170600	NP_733745	Q8N5H7	SH2D3_HUMAN	SH2 domain containing 3C isoform a	428					JNK cascade|small GTPase mediated signal transduction	cytoplasm|membrane	guanyl-nucleotide exchange factor activity|SH3/SH2 adaptor activity			ovary(1)	1														0.431373	63.846995	64.055145	22	29	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	129547182	129547182	14725	9	C	T	T	27	27	SH2D3C	T	1	1
NOTCH1	4851	broad.mit.edu	36	9	138520058	138520058	+	Missense_Mutation	SNP	T	G	G			TCGA-26-5133-01	TCGA-26-5133-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr9:138520058T>G	uc004chz.1	-	c.4111A>C	c.(4111-4113)ACC>CCC	p.T1371P	NOTCH1_uc004cia.1_Missense_Mutation_p.T601P	NM_017617	NP_060087	P46531	NOTC1_HUMAN	notch1 preproprotein	1371	Extracellular (Potential).|EGF-like 35.				aortic valve morphogenesis|immune response|negative regulation of BMP signaling pathway|negative regulation of cell-substrate adhesion|negative regulation of gene-specific transcription|negative regulation of myoblast differentiation|negative regulation of osteoblast differentiation|Notch receptor processing	cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to membrane|nucleoplasm|plasma membrane	calcium ion binding|protein binding|receptor activity			haematopoietic_and_lymphoid_tissue(781)|lung(11)|central_nervous_system(10)|breast(4)|upper_aerodigestive_tract(1)|large_intestine(1)|oesophagus(1)|pancreas(1)	810	all_cancers(76;0.223)	Myeloproliferative disorder(178;0.0511)								1552				0.6	13.970393	14.064679	9	6	TT		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(145;5.34e-06)|Epithelial(140;7.77e-06)	Missense_Mutation	SNP	138520058	138520058	10950	9	T	G	G	59	59	NOTCH1	G	4	4
CITED1	4435	broad.mit.edu	36	X	71439433	71439433	+	Silent	SNP	C	T	T			TCGA-26-5133-01	TCGA-26-5133-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chrX:71439433C>T	uc004eas.1	-	c.12G>A	c.(10-12)ACG>ACA	p.T4T	CITED1_uc004eat.1_Silent_p.T4T	NM_004143	NP_004134	Q99966	CITE1_HUMAN	melanocyte-specific gene 1 isoform 1	4					branching involved in ureteric bud morphogenesis|cell proliferation|melanin biosynthetic process|melanocyte differentiation|mesenchymal to epithelial transition|metanephros development|negative regulation of neuron apoptosis|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-dependent|negative regulation of Wnt receptor signaling pathway|nucleocytoplasmic transport|placenta development|positive regulation of anti-apoptosis|positive regulation of transcription, DNA-dependent|positive regulation of transforming growth factor beta receptor signaling pathway|regulation of transcription from RNA polymerase II promoter|response to cAMP|response to estrogen stimulus|response to insulin stimulus|response to interferon-gamma|response to interleukin-1|response to interleukin-11|response to interleukin-2|response to interleukin-4|response to interleukin-6|response to interleukin-9|response to lipopolysaccharide|response to parathyroid hormone stimulus|response to transforming growth factor beta stimulus|SMAD protein signal transduction|transforming growth factor beta receptor signaling pathway	cytosol|nucleus	co-SMAD binding|LBD domain binding|promoter binding|protein C-terminus binding|protein homodimerization activity|sequence-specific DNA binding transcription factor activity|transcription activator activity|transcription coactivator activity|transcription repressor activity				0	Renal(35;0.156)													0.176471	11.829168	15.183281	6	28	CC		KEEP	---	---	---	---	capture			Silent	SNP	71439433	71439433	3574	23	C	T	T	19	19	CITED1	T	1	1
NF1	4763	broad.mit.edu	36	17	26691654	26691654	+	Frame_Shift_Del	DEL	G	-	-			TCGA-26-5133-01	TCGA-26-5133-01										Phase_I	Unspecified				Illumina GAIIx	g.chr17:26691654_26691654delG	uc002hgg.1	+	c.6927_6927delG	c.(6925-6927)TCGfs	p.S2309fs	NF1_uc002hgh.1_Frame_Shift_Del_p.S2288fs|NF1_uc010cso.1_Frame_Shift_Del_p.S497fs	NM_001042492	NP_001035957	P21359	NF1_HUMAN	neurofibromin isoform 1	2309					actin cytoskeleton organization|adrenal gland development|artery morphogenesis|camera-type eye morphogenesis|cerebral cortex development|collagen fibril organization|forebrain astrocyte development|forebrain morphogenesis|heart development|liver development|MAPKKK cascade|metanephros development|myelination in peripheral nervous system|negative regulation of cell migration|negative regulation of endothelial cell proliferation|negative regulation of MAP kinase activity|negative regulation of MAPKKK cascade|negative regulation of neuroblast proliferation|negative regulation of oligodendrocyte differentiation|negative regulation of transcription factor import into nucleus|osteoblast differentiation|phosphatidylinositol 3-kinase cascade|pigmentation|positive regulation of adenylate cyclase activity|positive regulation of neuron apoptosis|Ras protein signal transduction|regulation of blood vessel endothelial cell migration|regulation of bone resorption|response to hypoxia|smooth muscle tissue development|spinal cord development|sympathetic nervous system development|visual learning|wound healing	axon|cytoplasm|dendrite|intrinsic to internal side of plasma membrane|nucleus	protein binding|Ras GTPase activator activity	p.?(1)		soft_tissue(155)|central_nervous_system(56)|large_intestine(27)|lung(19)|haematopoietic_and_lymphoid_tissue(13)|ovary(12)|autonomic_ganglia(7)|skin(3)|stomach(2)|breast(2)|thyroid(1)|prostate(1)|kidney(1)|pancreas(1)	300		all_cancers(10;1.29e-12)|all_epithelial(10;0.00347)|all_hematologic(16;0.00556)|Acute lymphoblastic leukemia(14;0.00593)|Breast(31;0.014)|Myeloproliferative disorder(56;0.0255)|all_lung(9;0.0321)|Lung NSC(157;0.0659)		UCEC - Uterine corpus endometrioid carcinoma (4;4.38e-05)|all cancers(4;1.64e-26)|Epithelial(4;9.15e-23)|OV - Ovarian serous cystadenocarcinoma(4;3.58e-21)|GBM - Glioblastoma multiforme(4;0.00146)						847	TCGA GBM(6;<1E-8)|TSP Lung(7;0.0071)|TCGA Ovarian(3;0.0088)			0.70			61	26				---	---	---	---	capture_indel			Frame_Shift_Del	DEL	26691654	26691654	10756	17	G	-	-	38	38	NF1	-	5	5
TMEM44	93109	broad.mit.edu	36	3	195806446	195806446	+	Frame_Shift_Del	DEL	G	-	-			TCGA-26-5133-01	TCGA-26-5133-01										Phase_I	Unspecified				Illumina GAIIx	g.chr3:195806446_195806446delG	uc010hzn.1	-	c.1176_1176delC	c.(1174-1176)ACCfs	p.T392fs	TMEM44_uc003fud.1_Frame_Shift_Del_p.T345fs|TMEM44_uc003fue.1_Frame_Shift_Del_p.T345fs|TMEM44_uc003fuf.1_Frame_Shift_Del_p.P344fs|TMEM44_uc003fuh.1_Non-coding_Transcript|TMEM44_uc010hzm.1_Frame_Shift_Del_p.P76fs|TMEM44_uc003fuc.1_Frame_Shift_Del_p.T77fs	NM_001011655	NP_001011655	Q2T9K0	TMM44_HUMAN	transmembrane protein 44 isoform b	392	Cytoplasmic (Potential).					integral to membrane					0	all_cancers(143;1.41e-08)|Ovarian(172;0.0634)		OV - Ovarian serous cystadenocarcinoma(49;4.34e-18)|LUSC - Lung squamous cell carcinoma(58;3.55e-06)|Lung(62;4.19e-06)	GBM - Glioblastoma multiforme(46;9.06e-06)										0.33			2	4				---	---	---	---	capture_indel			Frame_Shift_Del	DEL	195806446	195806446	16707	3	G	-	-	47	47	TMEM44	-	5	5
PCDHGB1	56104	broad.mit.edu	36	5	140710079	140710080	+	Frame_Shift_Del	DEL	TC	-	-			TCGA-26-5133-01	TCGA-26-5133-01										Phase_I	Unspecified				Illumina GAIIx	g.chr5:140710079_140710080delTC	uc003ljo.1	+	c.68_69delTC	c.(67-69)TTCfs	p.F23fs	PCDHGA1_uc003lji.1_Intron|PCDHGA2_uc003ljk.1_Intron|PCDHGA3_uc010jfx.1_Intron|PCDHGA3_uc003ljm.1_Intron|PCDHGB1_uc003ljn.1_Frame_Shift_Del_p.F23fs	NM_018922	NP_061745	Q9Y5G3	PCDGD_HUMAN	protocadherin gamma subfamily B, 1 isoform 1	23					homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding				0			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)									OREG0016856	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.82			14	3				---	---	---	---	capture_indel			Frame_Shift_Del	DEL	140710079	140710080	11982	5	TC	-	-	62	62	PCDHGB1	-	5	5
