Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Genome_Change	Annotation_Transcript	Transcript_Strand	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	i_TCGAscape_Amplification_Peaks	i_TCGAscape_Deletion_Peaks	DrugBank	i_ACHILLES_Top_Genes	i_CCLE_ONCOMAP_overlapping_mutations	i_CCLE_ONCOMAP_total_mutations_in_gene	i_CCLE_SEQ_overlapping_mutations	i_CCLE_SEQ_total_mutations_in_gene	MUTSIG_Significant_Genes	OREGANNO_ID	OREGANNO_Values	i_tumor_f	i_init_t_lod	i_t_lod_fstar	i_t_alt_count	i_t_ref_count	i_normal_best_gt	i_failure_reasons	i_judgement	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	dataset	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	type	classification	start	end	gene	chr	ref_allele	tum_allele1	tum_allele2	context_orig	context65	gene_name	newbase	categ	categ_ignoring_null_categ
ZNF37A	7587	broad.mit.edu	36	10	38447554	38447554	+	Missense_Mutation	SNP	T	C	C			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr10:38447554T>C	uc001izk.1	+	c.1469T>C	c.(1468-1470)ATA>ACA	p.I490T	ZNF37A_uc001izl.1_Missense_Mutation_p.I490T|ZNF37A_uc001izm.1_Missense_Mutation_p.I490T	NM_001007094	NP_003412	P17032	ZN37A_HUMAN	zinc finger protein 37a	490					regulation of transcription, DNA-dependent	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)	1														0.772727	65.087912	66.590532	17	5	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	38447554	38447554	18464	10	T	C	C	49	49	ZNF37A	C	4	4
PGR	5241	broad.mit.edu	36	11	100504881	100504881	+	Missense_Mutation	SNP	G	T	T			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr11:100504881G>T	uc001pgh.2	-	c.131C>A	c.(130-132)ACC>AAC	p.T44N	PGR_uc001pgi.2_Missense_Mutation_p.T44N|PGR_uc009yww.1_Non-coding_Transcript|PGR_uc001pgj.2_Non-coding_Transcript|PGR_uc009ywx.1_Non-coding_Transcript	NM_000926	NP_000917	P06401	PRGR_HUMAN	progesterone receptor	44	Modulating, Pro-Rich.				cell-cell signaling|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	cytoplasm|nucleoplasm	enzyme binding|receptor binding|sequence-specific DNA binding transcription factor activity|steroid binding|steroid hormone receptor activity|zinc ion binding			lung(1)|liver(1)|central_nervous_system(1)|pancreas(1)	4		Acute lymphoblastic leukemia(157;0.000885)|all_hematologic(158;0.014)			Desogestrel(DB00304)|Drospirenone(DB01395)|Dydrogesterone(DB00378)|Ethynodiol Diacetate(DB00823)|Etonogestrel(DB00294)|Levonorgestrel(DB00367)|Medroxyprogesterone(DB00603)|Megestrol(DB00351)|Mifepristone(DB00834)|Norethindrone(DB00717)|Norgestimate(DB00957)|Norgestrel(DB00506)|Progesterone(DB00396)	Pancreas(124;2271 2354 21954 22882)				429				0.416667	15.672791	15.745579	5	7	GG		KEEP	---	---	---	---	capture		LUSC - Lung squamous cell carcinoma(1;0.0387)|BRCA - Breast invasive adenocarcinoma(274;0.124)|OV - Ovarian serous cystadenocarcinoma(223;0.148)|Lung(307;0.164)	Missense_Mutation	SNP	100504881	100504881	12228	11	G	T	T	44	44	PGR	T	3	3
GLT8D2	83468	broad.mit.edu	36	12	102914710	102914710	+	Missense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:102914710G>A	uc001tkh.1	-	c.533C>T	c.(532-534)GCG>GTG	p.A178V	GLT8D2_uc001tki.1_Missense_Mutation_p.A178V	NM_031302	NP_112592	Q9H1C3	GL8D2_HUMAN	glycosyltransferase 8 domain containing 2	178	Lumenal (Potential).					integral to membrane	transferase activity, transferring glycosyl groups			ovary(1)	1														0.371429	71.629281	72.646786	26	44	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	102914710	102914710	6738	12	G	A	A	38	38	GLT8D2	A	1	1
CUX2	23316	broad.mit.edu	36	12	110256724	110256724	+	Missense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:110256724G>A	uc001tsa.1	+	c.3023G>A	c.(3022-3024)AGC>AAC	p.S1008N		NM_015267	NP_056082	O14529	CUX2_HUMAN	cut-like 2	1008						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			ovary(3)|breast(1)	4														0.358974	37.476123	38.184977	14	25	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	110256724	110256724	4225	12	G	A	A	34	34	CUX2	A	2	2
COL2A1	1280	broad.mit.edu	36	12	46658065	46658065	+	Nonsense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr12:46658065G>A	uc001rqu.1	-	c.3106C>T	c.(3106-3108)CGA>TGA	p.R1036*	COL2A1_uc009zkw.1_Non-coding_Transcript|COL2A1_uc001rqv.1_Nonsense_Mutation_p.R967*|COL2A1_uc001rqt.1_5'Flank	NM_001844	NP_001835	P02458	CO2A1_HUMAN	collagen, type II, alpha 1 isoform 1 precursor	1036	Triple-helical region.				axon guidance|collagen fibril organization|embryonic skeletal joint morphogenesis|sensory perception of sound|visual perception	collagen type II	extracellular matrix structural constituent conferring tensile strength|identical protein binding|platelet-derived growth factor binding			ovary(1)	1		Acute lymphoblastic leukemia(13;0.108)|all_hematologic(14;0.214)			Collagenase(DB00048)									0.333333	9.189739	9.488093	4	8	GG		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	46658065	46658065	3825	12	G	A	A	40	40	COL2A1	A	5	1
ZC3H10	84872	broad.mit.edu	36	12	54800720	54800720	+	Missense_Mutation	SNP	C	G	G			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr12:54800720C>G	uc001sjp.1	+	c.107C>G	c.(106-108)GCC>GGC	p.A36G	ZC3H10_uc009zon.1_Missense_Mutation_p.A36G	NM_032786	NP_116175	Q96K80	ZC3HA_HUMAN	zinc finger CCCH-type containing 10	36	C3H1-type 1.						nucleic acid binding|zinc ion binding				0														0.235294	9.290819	10.380692	4	13	CC		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(18;0.12)		Missense_Mutation	SNP	54800720	54800720	18147	12	C	G	G	26	26	ZC3H10	G	3	3
SRGAP1	57522	broad.mit.edu	36	12	62808217	62808217	+	Missense_Mutation	SNP	C	A	A			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr12:62808217C>A	uc001sru.1	+	c.2850C>A	c.(2848-2850)CAC>CAA	p.H950Q	SRGAP1_uc001srv.1_Missense_Mutation_p.H887Q	NM_020762	NP_065813	Q7Z6B7	SRGP1_HUMAN	SLIT-ROBO Rho GTPase activating protein 1	950					axon guidance	cytosol				ovary(2)|central_nervous_system(2)	4														0.214286	6.97833	9.194933	6	22	CC		KEEP	---	---	---	---	capture	GBM - Glioblastoma multiforme(3;0.000139)|BRCA - Breast invasive adenocarcinoma(9;0.225)	GBM - Glioblastoma multiforme(28;0.0608)	Missense_Mutation	SNP	62808217	62808217	15659	12	C	A	A	17	17	SRGAP1	A	3	3
ABCC4	10257	broad.mit.edu	36	13	94503393	94503393	+	Missense_Mutation	SNP	A	C	C			TCGA-87-5896-01	TCGA-87-5896-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr13:94503393A>C	uc001vmd.2	-	c.3413T>G	c.(3412-3414)TTT>TGT	p.F1138C	ABCC4_uc010afj.1_Missense_Mutation_p.F22C|ABCC4_uc010afk.1_Missense_Mutation_p.F1091C	NM_005845	NP_005836	O15439	MRP4_HUMAN	ATP-binding cassette, sub-family C, member 4	1138	ABC transporter 2.				platelet activation|platelet degranulation	integral to membrane|membrane fraction|plasma membrane|platelet dense granule membrane	15-hydroxyprostaglandin dehydrogenase (NAD+) activity|ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|chloride channel activity			central_nervous_system(3)	3	all_neural(89;0.0878)|Medulloblastoma(90;0.163)				Cefazolin(DB01327)					1222				0.3	59.028636	61.171535	18	42	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	94503393	94503393	56	13	A	C	C	1	1	ABCC4	C	4	4
MGAT2	4247	broad.mit.edu	36	14	49158822	49158822	+	Nonsense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr14:49158822G>A	uc001wwr.1	+	c.1086G>A	c.(1084-1086)TGG>TGA	p.W362*	SDCCAG1_uc010anj.1_Intron|RPL36AL_uc001wwq.1_5'Flank	NM_002408	NP_002399	Q10469	MGAT2_HUMAN	mannosyl (alpha-1,6-)-glycoprotein	362	Lumenal (Potential).				oligosaccharide biosynthetic process|post-translational protein modification|protein N-linked glycosylation via asparagine	Golgi membrane|Golgi stack|integral to membrane|membrane fraction	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity				0	all_epithelial(31;0.0021)|Breast(41;0.0124)													0.305882	75.428493	78.279197	26	59	GG		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	49158822	49158822	9933	14	G	A	A	41	41	MGAT2	A	5	2
PAK6	56924	broad.mit.edu	36	15	38345613	38345613	+	Silent	SNP	C	G	G			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr15:38345613C>G	uc010bbl.1	+	c.483C>G	c.(481-483)CCC>CCG	p.P161P	PAK6_uc010bbm.1_Silent_p.P161P|PAK6_uc001zky.2_Silent_p.P161P|PAK6_uc010bbn.1_Silent_p.P161P|PAK6_uc001zlb.2_Silent_p.P161P	NM_001128628	NP_001122100	Q9NQU5	PAK6_HUMAN	p21-activated kinase 6	161	Linker.				protein phosphorylation		ATP binding|protein binding|protein serine/threonine kinase activity			lung(3)|large_intestine(1)|ovary(1)	5		all_cancers(109;1.13e-18)|all_epithelial(112;1.62e-15)|Lung NSC(122;5.67e-11)|all_lung(180;1.41e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0823)|Colorectal(260;0.117)							p.P161P(FADU-Tumor)	94				0.266667	6.658712	7.426664	4	11	CC		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(113;1.51e-05)|BRCA - Breast invasive adenocarcinoma(123;0.0544)	Silent	SNP	38345613	38345613	11820	15	C	G	G	23	23	PAK6	G	3	3
UBR1	197131	broad.mit.edu	36	15	41056320	41056320	+	Missense_Mutation	SNP	T	A	A			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr15:41056320T>A	uc001zqq.1	-	c.4256A>T	c.(4255-4257)GAT>GTT	p.D1419V		NM_174916	NP_777576	Q8IWV7	UBR1_HUMAN	ubiquitin protein ligase E3 component n-recognin	1419						cytosol	zinc ion binding			lung(1)	1		all_cancers(109;4.32e-15)|all_epithelial(112;4.05e-13)|Lung NSC(122;1.75e-08)|all_lung(180;2e-07)|Melanoma(134;0.0179)|Colorectal(260;0.215)												0.382353	36.26264	36.676518	13	21	TT		KEEP	---	---	---	---	capture		GBM - Glioblastoma multiforme(94;4.08e-07)|COAD - Colon adenocarcinoma(120;0.185)|Colorectal(105;0.214)	Missense_Mutation	SNP	41056320	41056320	17459	15	T	A	A	50	50	UBR1	A	4	4
EDC3	80153	broad.mit.edu	36	15	72712131	72712131	+	Missense_Mutation	SNP	C	A	A			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr15:72712131C>A	uc002aym.1	-	c.1402G>T	c.(1402-1404)GGG>TGG	p.G468W	EDC3_uc002ayn.1_Missense_Mutation_p.G468W|EDC3_uc002ayo.1_Missense_Mutation_p.G468W	NM_025083	NP_079359	Q96F86	EDC3_HUMAN	enhancer of mRNA decapping 3	468	YjeF N-terminal.				exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	cytoplasmic mRNA processing body|cytosol	protein binding			ovary(1)	1												OREG0023286	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.4	43.004833	43.349924	16	24	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	72712131	72712131	5094	15	C	A	A	22	22	EDC3	A	3	3
HYDIN	54768	broad.mit.edu	36	16	69485935	69485935	+	Missense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr16:69485935C>T	uc002ezr.1	-	c.9163G>A	c.(9163-9165)GAT>AAT	p.D3055N	HYDIN_uc002ezs.1_Missense_Mutation_p.D587N	NM_032821	NP_116210	Q4G0P3	HYDIN_HUMAN	hydrocephalus inducing isoform a	3056										ovary(1)	1		Ovarian(137;0.0654)												0.217391	34.971925	40.072472	15	54	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	69485935	69485935	7767	16	C	T	T	30	30	HYDIN	T	2	2
SPG7	6687	broad.mit.edu	36	16	88125962	88125962	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr16:88125962G>A	uc002fnj.1	+	c.1137G>A	c.(1135-1137)GTG>GTA	p.V379V	SPG7_uc002fni.1_Silent_p.V379V	NM_003119	NP_003110	Q9UQ90	SPG7_HUMAN	spastic paraplegia 7 isoform 1	379	Mitochondrial matrix (Potential).				cell death|nervous system development|protein catabolic process|proteolysis	integral to membrane|mitochondrial membrane	ATP binding|metalloendopeptidase activity|nucleoside-triphosphatase activity|unfolded protein binding|zinc ion binding				0		all_hematologic(23;0.00824)|Colorectal(91;0.102)												0.375	26.668539	26.997969	9	15	GG		KEEP	---	---	---	---	capture		all cancers(4;1.39e-07)|OV - Ovarian serous cystadenocarcinoma(4;5.64e-06)|BRCA - Breast invasive adenocarcinoma(80;0.015)	Silent	SNP	88125962	88125962	15556	16	G	A	A	47	47	SPG7	A	2	2
CCL2	6347	broad.mit.edu	36	17	29607471	29607471	+	Missense_Mutation	SNP	T	A	A			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr17:29607471T>A	uc002hhy.1	+	c.194T>A	c.(193-195)ATC>AAC	p.I65N		NM_002982	NP_002973	P13500	CCL2_HUMAN	small inducible cytokine A2 precursor	65				Missing: 90% reduction in activity.|Missing: 83% reduction in activity.	angiogenesis|anti-apoptosis|apoptotic cell clearance|astrocyte cell migration|cell adhesion|cellular response to interferon-gamma|cellular response to interleukin-1|cellular response to lipopolysaccharide|cellular response to tumor necrosis factor|G-protein signaling, coupled to cyclic nucleotide second messenger|helper T cell extravasation|humoral immune response|inflammatory response|JAK-STAT cascade|macrophage chemotaxis|monocyte chemotaxis|positive regulation of nitric-oxide synthase biosynthetic process|positive regulation of T cell activation|protein phosphorylation|viral genome replication	extracellular space	CCR2 chemokine receptor binding|chemokine activity|protein kinase activity|signal transducer activity			pancreas(1)	1	Breast(3;0.00224)	Ovarian(249;0.0694)|Breast(31;0.151)|Lung NSC(157;0.153)			Atorvastatin(DB01076)|Danazol(DB01406)|Mimosine(DB01055)|Simvastatin(DB00641)									0.423077	36.221833	36.35582	11	15	TT		KEEP	---	---	---	---	capture		UCEC - Uterine corpus endometrioid carcinoma (308;0.000241)|BRCA - Breast invasive adenocarcinoma(366;0.0103)	Missense_Mutation	SNP	29607471	29607471	3016	17	T	A	A	51	51	CCL2	A	4	4
TNS4	84951	broad.mit.edu	36	17	35894751	35894751	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr17:35894751G>A	uc010cxb.1	-	c.1323C>T	c.(1321-1323)TTC>TTT	p.F441F		NM_032865	NP_116254	Q8IZW8	TENS4_HUMAN	tensin 4	441					apoptosis|protein localization	cytoplasm|cytoskeleton|focal adhesion	actin binding			large_intestine(1)|ovary(1)|central_nervous_system(1)	3		Breast(137;0.000496)												0.325	36.861074	37.948158	13	27	GG		KEEP	---	---	---	---	capture	STAD - Stomach adenocarcinoma(5;5.91e-05)		Silent	SNP	35894751	35894751	16886	17	G	A	A	37	37	TNS4	A	1	1
SGCA	6442	broad.mit.edu	36	17	45601590	45601590	+	Silent	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr17:45601590C>T	uc002iqi.1	+	c.723C>T	c.(721-723)CGC>CGT	p.R241R	SGCA_uc002iqj.1_Intron	NM_000023	NP_000014	Q16586	SGCA_HUMAN	sarcoglycan, alpha isoform 1 precursor	241	Extracellular (Potential).				muscle contraction|muscle organ development	cytoplasm|cytoskeleton|integral to membrane|sarcoglycan complex|sarcolemma	calcium ion binding			ovary(2)	2												OREG0024558	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.307692	10.395034	10.823682	4	9	CC		KEEP	---	---	---	---	capture			Silent	SNP	45601590	45601590	14690	17	C	T	T	27	27	SGCA	T	1	1
EPX	8288	broad.mit.edu	36	17	53632731	53632731	+	Nonsense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr17:53632731C>T	uc002ivq.2	+	c.1684C>T	c.(1684-1686)CGA>TGA	p.R562*		NM_000502	NP_000493	P11678	PERE_HUMAN	eosinophil peroxidase	562					hydrogen peroxide catabolic process|oxidation-reduction process		heme binding|peroxidase activity|protein binding			ovary(2)	2												OREG0024608	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.371429	36.382907	36.884326	13	22	CC		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	53632731	53632731	5393	17	C	T	T	19	19	EPX	T	5	1
ENPP7	339221	broad.mit.edu	36	17	75326409	75326409	+	Missense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr17:75326409G>A	uc002jxa.1	+	c.1346G>A	c.(1345-1347)GGG>GAG	p.G449E		NM_178543	NP_848638	Q6UWV6	ENPP7_HUMAN	ectonucleotide pyrophosphatase/phosphodiesterase	449	Helical; (Potential).				negative regulation of cell proliferation|negative regulation of DNA replication|sphingomyelin metabolic process	Golgi apparatus|integral to membrane|microvillus	sphingomyelin phosphodiesterase activity			central_nervous_system(2)|ovary(1)	3														0.44	68.357437	68.511254	22	28	GG		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(97;0.016)|BRCA - Breast invasive adenocarcinoma(99;0.0224)		Missense_Mutation	SNP	75326409	75326409	5328	17	G	A	A	43	43	ENPP7	A	2	2
SERPINB11	89778	broad.mit.edu	36	18	59538370	59538370	+	Splice_Site_SNP	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr18:59538370G>A	uc002ljk.2	+	c.618_splice	c.e7+1	p.E206_splice	SERPINB11_uc010dqd.1_Splice_Site_SNP_p.E92_splice|SERPINB11_uc002ljj.2_Splice_Site_SNP_p.E92_splice|SERPINB11_uc010dqe.1_Intron|SERPINB11_uc010dqf.1_Intron	NM_080475	NP_536723			serpin peptidase inhibitor, clade B, member 11						regulation of proteolysis	cytoplasm	serine-type endopeptidase inhibitor activity			breast(1)	1		Esophageal squamous(42;0.129)				Ovarian(27;496 784 5942 8975 23930)								0.347826	23.492598	23.962922	8	15	GG		KEEP	---	---	---	---	capture			Splice_Site_SNP	SNP	59538370	59538370	14586	18	G	A	A	44	44	SERPINB11	A	5	2
LAMA1	284217	broad.mit.edu	36	18	6967852	6967852	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr18:6967852G>A	uc002knm.1	-	c.6219C>T	c.(6217-6219)GAC>GAT	p.D2073D		NM_005559	NP_005550	P25391	LAMA1_HUMAN	laminin, alpha 1 precursor	2073	Domain II and I.				axon guidance|cell adhesion|cell surface receptor linked signaling pathway|regulation of cell adhesion|regulation of cell migration|regulation of embryonic development	extracellular space|laminin-1 complex|laminin-3 complex	extracellular matrix structural constituent|receptor binding			ovary(8)|large_intestine(4)|breast(2)|pancreas(2)|central_nervous_system(1)	17		Colorectal(10;0.172)			Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)					1597				0.357143	13.570689	13.822499	5	9	GG		KEEP	---	---	---	---	capture			Silent	SNP	6967852	6967852	8928	18	G	A	A	40	40	LAMA1	A	1	1
KRTDAP	388533	broad.mit.edu	36	19	40671419	40671419	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:40671419G>A	uc002nzh.1	-	c.153C>T	c.(151-153)ATC>ATT	p.I51I		NM_207392	NP_997275	P60985	KTDAP_HUMAN	keratinocyte differentiation-associated protein	51					cell differentiation	extracellular region					0	all_lung(56;1.89e-08)|Lung NSC(56;2.9e-08)|Esophageal squamous(110;0.162)													0.259843	85.718889	92.350143	33	94	GG		KEEP	---	---	---	---	capture	LUSC - Lung squamous cell carcinoma(66;0.0724)		Silent	SNP	40671419	40671419	8903	19	G	A	A	37	37	KRTDAP	A	1	1
SIPA1L3	23094	broad.mit.edu	36	19	43313085	43313085	+	Silent	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr19:43313085C>T	uc002ohk.1	+	c.2976C>T	c.(2974-2976)GAC>GAT	p.D992D		NM_015073	NP_055888	O60292	SI1L3_HUMAN	signal-induced proliferation-associated 1 like	992	PDZ.				regulation of small GTPase mediated signal transduction	intracellular	GTPase activator activity			ovary(1)|central_nervous_system(1)	2														0.463415	114.84216	114.936661	38	44	CC		KEEP	---	---	---	---	capture	Lung(45;0.000246)|LUSC - Lung squamous cell carcinoma(53;0.000292)		Silent	SNP	43313085	43313085	14826	19	C	T	T	20	20	SIPA1L3	T	2	2
FCGBP	8857	broad.mit.edu	36	19	45084200	45084200	+	Missense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:45084200G>A	uc002omp.2	-	c.8144C>T	c.(8143-8145)GCA>GTA	p.A2715V		NM_003890	NP_003881	Q9Y6R7	FCGBP_HUMAN	Fc fragment of IgG binding protein	2715						extracellular region	protein binding			ovary(4)|central_nervous_system(1)	5	all_cancers(60;6.03e-06)|all_lung(34;5.58e-08)|Lung NSC(34;6.62e-08)|Ovarian(47;0.06)													1	24.241446	24.233626	7	0	GG		KEEP	---	---	---	---	capture	Epithelial(26;6.25e-23)|all cancers(26;1.13e-20)		Missense_Mutation	SNP	45084200	45084200	6015	19	G	A	A	46	46	FCGBP	A	2	2
CEACAM3	1084	broad.mit.edu	36	19	46993422	46993422	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:46993422G>A	uc002orn.1	+	c.126G>A	c.(124-126)CCG>CCA	p.P42P	CEACAM3_uc010eia.1_Silent_p.P42P|CEACAM3_uc002oro.1_Non-coding_Transcript	NM_001815	NP_001806	P40198	CEAM3_HUMAN	carcinoembryonic antigen-related cell adhesion	42	Ig-like V-type.|Extracellular (Potential).					integral to membrane					0														0.350515	93.222498	95.133774	34	63	GG		KEEP	---	---	---	---	capture			Silent	SNP	46993422	46993422	3326	19	G	A	A	38	38	CEACAM3	A	1	1
PSG1	5669	broad.mit.edu	36	19	48075565	48075565	+	Silent	SNP	G	T	T			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr19:48075565G>T	uc010eio.1	-	c.9C>A	c.(7-9)ACC>ACA	p.T3T	PSG10_uc002ouv.1_Intron|PSG3_uc002ouf.1_Intron|PSG1_uc002oug.1_Silent_p.T3T|PSG1_uc002oun.1_Non-coding_Transcript|PSG7_uc002ous.1_Intron|PSG7_uc002out.1_Intron|PSG11_uc002ouw.1_Intron|PSG1_uc002our.1_Silent_p.T3T|PSG1_uc002oux.1_5'Flank|PSG1_uc002ouy.1_Silent_p.T3T|PSG1_uc002ouz.1_Silent_p.T3T|PSG1_uc002ova.1_Silent_p.T3T|PSG1_uc002ovb.2_Silent_p.T3T|PSG1_uc002ovc.2_Silent_p.T3T|PSG1_uc002ovd.1_Silent_p.T3T	NM_006905	NP_008836	P11464	PSG1_HUMAN	pregnancy specific beta-1-glycoprotein 1	3					female pregnancy	extracellular region				ovary(2)	2		Prostate(69;0.00682)												0.221154	50.258561	57.71485	23	81	GG		KEEP	---	---	---	---	capture			Silent	SNP	48075565	48075565	13106	19	G	T	T	43	43	PSG1	T	3	3
PTPRS	5802	broad.mit.edu	36	19	5224496	5224496	+	Silent	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr19:5224496C>T	uc002mbv.1	-	c.336G>A	c.(334-336)TCG>TCA	p.S112S	PTPRS_uc002mbu.1_Silent_p.S112S|PTPRS_uc002mbw.1_Silent_p.S112S|PTPRS_uc002mbx.1_Silent_p.S112S|PTPRS_uc002mby.1_Silent_p.S112S|PTPRS_uc002mbz.1_Silent_p.S112S	NM_002850	NP_002841	Q13332	PTPRS_HUMAN	protein tyrosine phosphatase, receptor type,	112	Ig-like C2-type 1.|Extracellular (Potential).				cell adhesion	integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity			large_intestine(2)|ovary(1)|central_nervous_system(1)	4														0.3125	39.816047	41.313743	15	33	CC		KEEP	---	---	---	---	capture		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0321)|Lung(535;0.182)	Silent	SNP	5224496	5224496	13269	19	C	T	T	23	23	PTPRS	T	1	1
KCND3	3752	broad.mit.edu	36	1	112325971	112325971	+	Missense_Mutation	SNP	A	G	G			TCGA-87-5896-01	TCGA-87-5896-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr1:112325971A>G	uc001ebu.1	-	c.901T>C	c.(901-903)TCC>CCC	p.S301P	KCND3_uc001ebv.1_Missense_Mutation_p.S301P	NM_004980	NP_004971	Q9UK17	KCND3_HUMAN	potassium voltage-gated channel, Shal-related	301	Helical; Voltage-sensor; Name=Segment S4; (Potential).					sarcolemma|voltage-gated potassium channel complex	A-type (transient outward) potassium channel activity|metal ion binding			ovary(2)|large_intestine(1)	3		all_cancers(81;8.52e-06)|all_epithelial(167;5.65e-06)|all_lung(203;2.72e-05)|Lung NSC(69;4.56e-05)												0.210526	6.566198	8.071009	4	15	AA		KEEP	---	---	---	---	capture		all cancers(265;0.056)|Lung(183;0.0576)|Colorectal(144;0.1)|Epithelial(280;0.104)|COAD - Colon adenocarcinoma(174;0.222)|LUSC - Lung squamous cell carcinoma(189;0.231)	Missense_Mutation	SNP	112325971	112325971	8325	1	A	G	G	9	9	KCND3	G	4	4
S100A7L2	645922	broad.mit.edu	36	1	151676173	151676173	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr1:151676173G>A	uc001fbu.1	-	c.291C>T	c.(289-291)TCC>TCT	p.S97S		NM_001045479	NP_001038944			S100 calcium binding protein A7-like 2											ovary(1)	1	all_lung(78;2.4e-33)|Lung NSC(65;8.13e-32)|Hepatocellular(266;0.0877)|Melanoma(130;0.199)													0.430303	224.59937	225.274646	71	94	GG		KEEP	---	---	---	---	capture	LUSC - Lung squamous cell carcinoma(543;0.171)		Silent	SNP	151676173	151676173	14265	1	G	A	A	39	39	S100A7L2	A	1	1
ZP4	57829	broad.mit.edu	36	1	236115134	236115134	+	Missense_Mutation	SNP	A	C	C			TCGA-87-5896-01	TCGA-87-5896-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr1:236115134A>C	uc001hym.1	-	c.1265T>G	c.(1264-1266)TTC>TGC	p.F422C		NM_021186	NP_067009	Q12836	ZP4_HUMAN	zona pellucida glycoprotein 4 preproprotein	422	ZP.|Extracellular (Potential).				acrosomal vesicle exocytosis|negative regulation of binding of sperm to zona pellucida|positive regulation of acrosome reaction|positive regulation of humoral immune response|positive regulation of protein kinase activity|positive regulation of T cell proliferation|protein kinase A signaling cascade|protein kinase C signaling cascade	integral to membrane|plasma membrane|proteinaceous extracellular matrix	acrosin binding|receptor activity			ovary(1)	1	Ovarian(103;0.103)	all_cancers(173;0.00175)|all_epithelial(177;0.162)|all_neural(198;0.164)|Melanoma(53;0.211)|Prostate(94;0.214)				NSCLC(166;160 2029 11600 18754 19936)								0.542857	68.553516	68.614305	19	16	AA		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(106;0.00989)		Missense_Mutation	SNP	236115134	236115134	18822	1	A	C	C	9	9	ZP4	C	4	4
OR2G6	391211	broad.mit.edu	36	1	246751896	246751896	+	Missense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:246751896C>T	uc001ien.1	+	c.326C>T	c.(325-327)TCG>TTG	p.S109L		NM_001013355	NP_001013373	Q5TZ20	OR2G6_HUMAN	olfactory receptor, family 2, subfamily G,	109	Helical; Name=3; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)	2	all_cancers(71;0.000108)|all_epithelial(71;1.03e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)	all_cancers(173;0.0156)												0.44	65.957013	66.110873	22	28	CC		KEEP	---	---	---	---	capture	OV - Ovarian serous cystadenocarcinoma(106;0.0265)		Missense_Mutation	SNP	246751896	246751896	11406	1	C	T	T	31	31	OR2G6	T	1	1
KTI12	112970	broad.mit.edu	36	1	52271099	52271099	+	Missense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:52271099C>T	uc001ctj.1	-	c.923G>A	c.(922-924)CGG>CAG	p.R308Q	TXNDC12_uc001cti.1_Intron	NM_138417	NP_612426	Q96EK9	KTI12_HUMAN	KTI12 homolog, chromatin associated	308							ATP binding			central_nervous_system(2)	2														0.486111	109.921148	109.933221	35	37	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	52271099	52271099	8907	1	C	T	T	23	23	KTI12	T	1	1
CACHD1	57685	broad.mit.edu	36	1	64913682	64913682	+	Missense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:64913682C>T	uc001dbo.1	+	c.2585C>T	c.(2584-2586)ACG>ATG	p.T862M	CACHD1_uc001dbp.1_Missense_Mutation_p.T617M|CACHD1_uc001dbq.1_Missense_Mutation_p.T617M	NM_020925	NP_065976	Q5VU97	CAHD1_HUMAN	cache domain containing 1	913	Extracellular (Potential).				calcium ion transport	integral to membrane				ovary(2)	2												OREG0013544	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	0.377778	48.364609	48.95421	17	28	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	64913682	64913682	2653	1	C	T	T	19	19	CACHD1	T	1	1
RPF1	80135	broad.mit.edu	36	1	84734226	84734226	+	Nonsense_Mutation	SNP	C	G	G			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr1:84734226C>G	uc001djv.2	+	c.773C>G	c.(772-774)TCA>TGA	p.S258*		NM_025065	NP_079341	Q9H9Y2	RPF1_HUMAN	RNA processing factor 1	258	Brix.				rRNA processing|translation	nucleolus	aminoacyl-tRNA ligase activity|ATP binding|rRNA binding				0														0.222222	18.064694	20.639385	8	28	CC		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	84734226	84734226	14025	1	C	G	G	29	29	RPF1	G	5	3
ODF2L	57489	broad.mit.edu	36	1	86623838	86623838	+	Missense_Mutation	SNP	T	A	A			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr1:86623838T>A	uc001dln.1	-	c.137A>T	c.(136-138)GAA>GTA	p.E46V	ODF2L_uc001dll.1_Missense_Mutation_p.E46V|ODF2L_uc001dlm.1_Missense_Mutation_p.E46V|ODF2L_uc001dlo.1_Intron|ODF2L_uc001dlp.1_Missense_Mutation_p.E46V|ODF2L_uc001dlq.1_Intron|ODF2L_uc009wcr.1_Intron	NM_020729	NP_001007023	Q9ULJ1	ODF2L_HUMAN	outer dense fiber of sperm tails 2-like isoform	46	Potential.									ovary(1)	1														0.266667	19.585589	21.06164	8	22	TT		KEEP	---	---	---	---	capture		all cancers(265;0.0313)|Epithelial(280;0.0611)	Missense_Mutation	SNP	86623838	86623838	11233	1	T	A	A	62	62	ODF2L	A	4	4
ST6GAL2	84620	broad.mit.edu	36	2	106826629	106826629	+	Silent	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:106826629C>T	uc002tdr.1	-	c.237G>A	c.(235-237)GCG>GCA	p.A79A	ST6GAL2_uc002tds.2_Silent_p.A79A	NM_032528	NP_115917	Q96JF0	SIAT2_HUMAN	ST6 beta-galactosamide	79	Lumenal (Potential).				growth|multicellular organismal development|oligosaccharide metabolic process|protein glycosylation	Golgi cisterna membrane|integral to Golgi membrane	beta-galactoside alpha-2,6-sialyltransferase activity	p.A79V(1)		pancreas(6)|ovary(3)	9														0.64	46.901343	47.332009	16	9	CC		KEEP	---	---	---	---	capture			Silent	SNP	106826629	106826629	15740	2	C	T	T	27	27	ST6GAL2	T	1	1
GAD1	2571	broad.mit.edu	36	2	171424568	171424568	+	Missense_Mutation	SNP	A	C	C			TCGA-87-5896-01	TCGA-87-5896-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr2:171424568A>C	uc002ugi.1	+	c.1715A>C	c.(1714-1716)AAC>ACC	p.N572T	GAD1_uc010fqc.1_Missense_Mutation_p.N191T	NM_000817	NP_000808	Q99259	DCE1_HUMAN	glutamate decarboxylase 1 isoform GAD67	572					glutamate decarboxylation to succinate|neurotransmitter biosynthetic process|neurotransmitter secretion|protein-pyridoxal-5-phosphate linkage	clathrin sculpted gamma-aminobutyric acid transport vesicle membrane|plasma membrane	glutamate decarboxylase activity|protein binding|pyridoxal phosphate binding			ovary(1)	1					L-Glutamic Acid(DB00142)|Pyridoxal Phosphate(DB00114)									0.307692	7.191626	7.687698	4	9	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	171424568	171424568	6430	2	A	C	C	2	2	GAD1	C	4	4
TTC15	51112	broad.mit.edu	36	2	3371079	3371079	+	Silent	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr2:3371079C>T	uc002qxm.1	+	c.678C>T	c.(676-678)TCC>TCT	p.S226S	TTC15_uc002qxn.1_Silent_p.S226S|TTC15_uc010ewm.1_Silent_p.S226S|TTC15_uc002qxl.1_Silent_p.S226S	NM_016030	NP_057114	Q8WVT3	TTC15_HUMAN	tetratricopeptide repeat domain 15	226							binding			ovary(2)|breast(1)|pancreas(1)	4	Acute lymphoblastic leukemia(172;0.0627)|all_hematologic(175;0.093)	all_cancers(51;0.214)												0.391304	28.670513	28.908326	9	14	CC		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(76;0.0402)|Epithelial(75;0.0986)|all cancers(51;0.149)	Silent	SNP	3371079	3371079	17236	2	C	T	T	24	24	TTC15	T	2	2
GPR149	344758	broad.mit.edu	36	3	155621779	155621779	+	Missense_Mutation	SNP	T	C	C			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr3:155621779T>C	uc003faa.1	-	c.1366A>G	c.(1366-1368)ATC>GTC	p.I456V		NM_001038705	NP_001033794	Q86SP6	GP149_HUMAN	G protein-coupled receptor 149	456	Cytoplasmic (Potential).					integral to membrane|plasma membrane	G-protein coupled receptor activity			ovary(6)	6														0.392308	171.391931	172.713415	51	79	TT		KEEP	---	---	---	---	capture	LUSC - Lung squamous cell carcinoma(72;0.114)|Lung(72;0.173)		Missense_Mutation	SNP	155621779	155621779	6929	3	T	C	C	52	52	GPR149	C	4	4
SI	6476	broad.mit.edu	36	3	166199052	166199052	+	Nonsense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr3:166199052G>A	uc003fei.1	-	c.4510C>T	c.(4510-4512)CGA>TGA	p.R1504*		NM_001041	NP_001032	P14410	SUIS_HUMAN	sucrase-isomaltase (alpha-glucosidase)	1504	Sucrase.|Lumenal.				carbohydrate metabolic process|polysaccharide digestion	apical plasma membrane|brush border|Golgi apparatus|integral to membrane	carbohydrate binding|oligo-1,6-glucosidase activity|sucrose alpha-glucosidase activity			ovary(7)|pancreas(1)	8		Prostate(884;0.00314)|Melanoma(1037;0.0153)|all_neural(597;0.0199)			Acarbose(DB00284)									0.363636	67.304863	68.37491	24	42	GG		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	166199052	166199052	14792	3	G	A	A	40	40	SI	A	5	1
TNIK	23043	broad.mit.edu	36	3	172282772	172282772	+	Missense_Mutation	SNP	T	G	G			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr3:172282772T>G	uc003fhh.1	-	c.3275A>C	c.(3274-3276)GAT>GCT	p.D1092A	TNIK_uc003fhi.1_Missense_Mutation_p.D1037A|TNIK_uc003fhj.1_Missense_Mutation_p.D1063A|TNIK_uc003fhk.1_Missense_Mutation_p.D1084A|TNIK_uc003fhl.1_Missense_Mutation_p.D1008A|TNIK_uc003fhm.1_Missense_Mutation_p.D1029A|TNIK_uc003fhn.1_Missense_Mutation_p.D1055A|TNIK_uc003fho.1_Missense_Mutation_p.D1000A|TNIK_uc003fhg.1_Missense_Mutation_p.D270A|TNIK_uc003fhp.1_Missense_Mutation_p.D24A	NM_015028	NP_055843	Q9UKE5	TNIK_HUMAN	TRAF2 and NCK interacting kinase	1092	CNH.				actin cytoskeleton reorganization|activation of JNKK activity|protein autophosphorylation|regulation of dendrite morphogenesis|Wnt receptor signaling pathway	cytoskeleton|nucleus|recycling endosome	ATP binding|protein binding|protein serine/threonine kinase activity|small GTPase regulator activity			ovary(4)|large_intestine(1)	5	all_cancers(22;2.55e-19)|all_lung(20;2.22e-14)|Ovarian(172;0.00197)|Breast(254;0.122)									743				0.428571	21.048779	21.110883	6	8	TT		KEEP	---	---	---	---	capture	LUSC - Lung squamous cell carcinoma(14;3.57e-14)|Lung(28;9.39e-14)		Missense_Mutation	SNP	172282772	172282772	16854	3	T	G	G	50	50	TNIK	G	4	4
LRIG1	26018	broad.mit.edu	36	3	66527268	66527268	+	Missense_Mutation	SNP	G	C	C			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr3:66527268G>C	uc003dmx.1	-	c.1354C>G	c.(1354-1356)CCC>GCC	p.P452A	LRIG1_uc010hnz.1_Missense_Mutation_p.P168A|LRIG1_uc010hoa.1_Missense_Mutation_p.P476A|LRIG1_uc003dmw.1_Missense_Mutation_p.P118A	NM_015541	NP_056356	Q96JA1	LRIG1_HUMAN	leucine-rich repeats and immunoglobulin-like	452	Extracellular (Potential).|LRRCT.					integral to membrane				ovary(2)|skin(1)	3		Lung NSC(201;0.0101)												0.5	6.972099	6.972099	5	5	GG		KEEP	---	---	---	---	capture		BRCA - Breast invasive adenocarcinoma(55;0.00047)	Missense_Mutation	SNP	66527268	66527268	9317	3	G	C	C	42	42	LRIG1	C	3	3
NSD1	64324	broad.mit.edu	36	5	176616733	176616733	+	Silent	SNP	T	C	C			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr5:176616733T>C	uc003mfr.2	+	c.4941T>C	c.(4939-4941)AAT>AAC	p.N1647N	NSD1_uc003mft.2_Silent_p.N1378N|NSD1_uc003mfs.1_Silent_p.N1544N	NM_022455	NP_071900	Q96L73	NSD1_HUMAN	nuclear receptor binding SET domain protein 1	1647					negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleus	androgen receptor binding|chromatin binding|estrogen receptor binding|histone methyltransferase activity (H3-K36 specific)|histone methyltransferase activity (H4-K20 specific)|ligand-dependent nuclear receptor binding|retinoid X receptor binding|thyroid hormone receptor binding|transcription corepressor activity|zinc ion binding			ovary(2)|kidney(1)	3	all_cancers(89;1.57e-05)|Renal(175;0.000269)|Lung NSC(126;0.00111)|all_lung(126;0.002)	all_neural(177;0.00409)|Medulloblastoma(196;0.00498)|all_hematologic(541;0.21)								492				0.24	7.248923	8.798694	6	19	TT		KEEP	---	---	---	---	capture	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)|Epithelial(233;0.198)	Kidney(146;0.235)	Silent	SNP	176616733	176616733	11074	5	T	C	C	50	50	NSD1	C	4	4
ADAMTS2	9509	broad.mit.edu	36	5	178484605	178484605	+	Missense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr5:178484605C>T	uc003mjw.1	-	c.2933G>A	c.(2932-2934)CGT>CAT	p.R978H		NM_014244	NP_055059	O95450	ATS2_HUMAN	ADAM metallopeptidase with thrombospondin type 1	978	TSP type-1 4.				collagen catabolic process	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			large_intestine(1)|lung(1)|ovary(1)|pancreas(1)	4	all_cancers(89;0.000456)|all_epithelial(37;0.000138)|Renal(175;0.000159)|Lung NSC(126;0.00184)|all_lung(126;0.00326)	all_cancers(40;0.00604)|all_neural(177;0.00411)|Medulloblastoma(196;0.00508)|Lung NSC(249;0.0569)|all_lung(500;0.129)|all_hematologic(541;0.211)								1974				0.466667	59.370664	59.414042	21	24	CC		KEEP	---	---	---	---	capture	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)	GBM - Glioblastoma multiforme(465;0.0473)	Missense_Mutation	SNP	178484605	178484605	266	5	C	T	T	19	19	ADAMTS2	T	1	1
FYB	2533	broad.mit.edu	36	5	39189444	39189444	+	Silent	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr5:39189444C>T	uc003jlt.1	-	c.1155G>A	c.(1153-1155)ACG>ACA	p.T385T	FYB_uc003jls.1_Silent_p.T385T|FYB_uc003jlu.1_Silent_p.T385T	NM_001465	NP_001456	O15117	FYB_HUMAN	FYN binding protein (FYB-120/130) isoform 1	385	Interaction with SKAP1.				cell junction assembly|immune response|intracellular protein kinase cascade|NLS-bearing substrate import into nucleus|protein phosphorylation|T cell receptor signaling pathway	cytosol|nucleus	protein binding			ovary(2)	2	all_lung(31;0.000343)													0.346154	48.430181	49.518581	18	34	CC		KEEP	---	---	---	---	capture	Epithelial(62;0.235)		Silent	SNP	39189444	39189444	6375	5	C	T	T	19	19	FYB	T	1	1
RGS7BP	401190	broad.mit.edu	36	5	63838239	63838239	+	Missense_Mutation	SNP	G	C	C			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr5:63838239G>C	uc003jtj.1	+	c.32G>C	c.(31-33)CGC>CCC	p.R11P		NM_001029875	NP_001025046	Q6MZT1	R7BP_HUMAN	regulator of G-protein signaling 7 binding	11					negative regulation of signal transduction	cytoplasm|nucleus|plasma membrane					0		Lung NSC(810;0.000518)|Prostate(74;0.0435)|Ovarian(174;0.186)												0.190476	7.486118	9.370494	4	17	GG		KEEP	---	---	---	---	capture		Lung(70;0.147)	Missense_Mutation	SNP	63838239	63838239	13785	5	G	C	C	38	38	RGS7BP	C	3	3
IQGAP2	10788	broad.mit.edu	36	5	76034164	76034164	+	Missense_Mutation	SNP	A	G	G			TCGA-87-5896-01	TCGA-87-5896-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chr5:76034164A>G	uc003kek.1	+	c.4607A>G	c.(4606-4608)AAT>AGT	p.N1536S	IQGAP2_uc003kel.1_Missense_Mutation_p.N1032S	NM_006633	NP_006624	Q13576	IQGA2_HUMAN	IQ motif containing GTPase activating protein 2	1536					small GTPase mediated signal transduction	actin cytoskeleton	actin binding|calmodulin binding|GTPase inhibitor activity|Ras GTPase activator activity			ovary(6)|central_nervous_system(1)	7		all_lung(232;0.000514)|Lung NSC(167;0.00135)|Prostate(461;0.00838)|Ovarian(174;0.0149)												0.323529	36.531827	37.462021	11	23	AA		KEEP	---	---	---	---	capture		all cancers(79;1.38e-36)	Missense_Mutation	SNP	76034164	76034164	8118	5	A	G	G	4	4	IQGAP2	G	4	4
DNAH8	1769	broad.mit.edu	36	6	39065795	39065795	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr6:39065795G>A	uc003ooe.1	+	c.12432G>A	c.(12430-12432)CCG>CCA	p.P4144P		NM_001371	NP_001362	Q96JB1	DYH8_HUMAN	dynein, axonemal, heavy polypeptide 8	4144					ciliary or flagellar motility|microtubule-based movement	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			ovary(6)|skin(5)|lung(2)|large_intestine(1)|central_nervous_system(1)|kidney(1)|pancreas(1)	17										2979				0.3625	82.952814	84.283836	29	51	GG		KEEP	---	---	---	---	capture			Silent	SNP	39065795	39065795	4790	6	G	A	A	40	40	DNAH8	A	1	1
GSTA1	2938	broad.mit.edu	36	6	52766904	52766904	+	Missense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr6:52766904C>T	uc003paz.1	-	c.392G>A	c.(391-393)CGC>CAC	p.R131H		NM_145740	NP_665683	P08263	GSTA1_HUMAN	glutathione S-transferase alpha 1	131	GST C-terminal.				glutathione metabolic process|xenobiotic metabolic process	cytosol	glutathione transferase activity			ovary(1)	1	Lung NSC(77;0.118)				Amsacrine(DB00276)|Busulfan(DB01008)|Glutathione(DB00143)									0.312169	154.761131	160.695441	59	130	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	52766904	52766904	7110	6	C	T	T	27	27	GSTA1	T	1	1
DSP	1832	broad.mit.edu	36	6	7510622	7510622	+	Missense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr6:7510622G>A	uc003mxp.1	+	c.809G>A	c.(808-810)CGA>CAA	p.R270Q	DSP_uc003mxq.1_Missense_Mutation_p.R270Q	NM_004415	NP_004406	P15924	DESP_HUMAN	desmoplakin isoform I	270	Globular 1.|Interacts with plakophilin 1 and junction plakoglobin.				cellular component disassembly involved in apoptosis|keratinocyte differentiation|peptide cross-linking	cornified envelope|cytoplasm|desmosome	protein binding, bridging|structural constituent of cytoskeleton			central_nervous_system(6)|ovary(2)	8	Ovarian(93;0.0584)	all_hematologic(90;0.236)												0.423077	66.14388	66.411665	22	30	GG		KEEP	---	---	---	---	capture		OV - Ovarian serous cystadenocarcinoma(45;0.000508)	Missense_Mutation	SNP	7510622	7510622	4965	6	G	A	A	37	37	DSP	A	1	1
EPHB6	2051	broad.mit.edu	36	7	142276155	142276155	+	Silent	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr7:142276155C>T	uc003wbq.1	+	c.1908C>T	c.(1906-1908)TAC>TAT	p.Y636Y	EPHB6_uc003wbr.1_Silent_p.Y636Y|EPHB6_uc003wbs.1_Silent_p.Y359Y|EPHB6_uc003wbt.1_Silent_p.Y125Y|EPHB6_uc003wbu.1_Silent_p.Y359Y|EPHB6_uc003wbv.1_Silent_p.Y35Y	NM_004445	NP_004436	O15197	EPHB6_HUMAN	ephrin receptor EphB6 precursor	651	Cytoplasmic (Potential).				protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway	extracellular region|integral to plasma membrane	ATP binding|ephrin receptor activity			lung(5)|large_intestine(4)|central_nervous_system(3)|ovary(1)|pancreas(1)	14	Melanoma(164;0.059)									313				0.4	67.38681	67.91136	24	36	CC		KEEP	---	---	---	---	capture			Silent	SNP	142276155	142276155	5371	7	C	T	T	19	19	EPHB6	T	1	1
ABCA13	154664	broad.mit.edu	36	7	48420775	48420775	+	Silent	SNP	G	T	T			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr7:48420775G>T	uc003toq.1	+	c.12018G>T	c.(12016-12018)CTG>CTT	p.L4006L	ABCA13_uc010kys.1_Silent_p.L1135L|ABCA13_uc010kyt.1_Non-coding_Transcript	NM_152701	NP_689914	Q86UQ4	ABCAD_HUMAN	ATP binding cassette, sub-family A (ABC1),	4061	ABC transporter 1.				transport	integral to membrane	ATP binding|ATPase activity			ovary(5)|central_nervous_system(4)|skin(1)	10														0.272	86.482154	92.350607	34	91	GG		KEEP	---	---	---	---	capture			Silent	SNP	48420775	48420775	32	7	G	T	T	45	45	ABCA13	T	3	3
POM121L12	285877	broad.mit.edu	36	7	53071542	53071542	+	Silent	SNP	C	A	A			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr7:53071542C>A	uc003tpz.1	+	c.684C>A	c.(682-684)TCC>TCA	p.S228S		NM_182595	NP_872401	Q8N7R1	P1L12_HUMAN	hypothetical protein LOC285877	228											0														0.291667	34.126578	35.995445	14	34	CC		KEEP	---	---	---	---	capture			Silent	SNP	53071542	53071542	12669	7	C	A	A	24	24	POM121L12	A	3	3
NSUN5	55695	broad.mit.edu	36	7	72355842	72355842	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr7:72355842G>A	uc003txv.1	-	c.1062C>T	c.(1060-1062)CTC>CTT	p.L354L	FKBP6_uc003twz.2_Intron|NSUN5_uc003txw.1_Silent_p.L354L|NSUN5_uc003txx.1_Silent_p.L316L	NM_148956	NP_683759	Q96P11	NSUN5_HUMAN	NOL1/NOP2/Sun domain family, member 5 isoform 1	354							methyltransferase activity				0		Lung NSC(55;0.163)												0.352941	33.59513	34.24112	12	22	GG		KEEP	---	---	---	---	capture			Silent	SNP	72355842	72355842	11086	7	G	A	A	37	37	NSUN5	A	1	1
MIOS	54468	broad.mit.edu	36	7	7579214	7579214	+	Nonsense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chr7:7579214C>T	uc003srf.1	+	c.583C>T	c.(583-585)CGA>TGA	p.R195*	MIOS_uc010ktp.1_Nonsense_Mutation_p.R195*	NM_019005	NP_061878	Q9NXC5	MIO_HUMAN	missing oocyte, meiosis regulator, homolog	195	WD 3.										0														0.269231	35.725937	38.225672	14	38	CC		KEEP	---	---	---	---	capture			Nonsense_Mutation	SNP	7579214	7579214	9979	7	C	T	T	19	19	MIOS	T	5	1
PALM2-AKAP2	445815	broad.mit.edu	36	9	111727168	111727168	+	Missense_Mutation	SNP	T	C	C			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chr9:111727168T>C	uc004bei.2	+	c.379T>C	c.(379-381)TCC>CCC	p.S127P	PALM2_uc004bef.1_Missense_Mutation_p.S129P|PALM2_uc004beg.1_Missense_Mutation_p.S129P|PALM2_uc004beh.2_Missense_Mutation_p.S127P|PALM2-AKAP2_uc004bek.2_Missense_Mutation_p.S127P|PALM2-AKAP2_uc004bej.2_Missense_Mutation_p.S127P|PALM2-AKAP2_uc004bel.1_5'UTR	NM_001004065	NP_001004065	Q9Y2D5	AKAP2_HUMAN	A kinase (PRKA) anchor protein 2 isoform 1	Error:Variant_position_missing_in_Q9Y2D5_after_alignment							enzyme binding			ovary(3)|central_nervous_system(2)	5														0.333333	34.71444	35.52604	11	22	TT		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	111727168	111727168	11826	9	T	C	C	54	54	PALM2-AKAP2	C	4	4
NOL8	55035	broad.mit.edu	36	9	94117571	94117571	+	Missense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chr9:94117571G>A	uc004arv.1	-	c.1157C>T	c.(1156-1158)GCG>GTG	p.A386V	NOL8_uc010mqw.1_Non-coding_Transcript|NOL8_uc004arw.1_Intron	NM_017948	NP_060418	Q76FK4	NOL8_HUMAN	nucleolar protein 8	386					DNA replication|positive regulation of cell growth	nucleolus	nucleotide binding|protein binding|RNA binding			ovary(1)	1														0.230769	7.118407	7.981854	3	10	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	94117571	94117571	10930	9	G	A	A	38	38	NOL8	A	1	1
WWC3	55841	broad.mit.edu	36	X	10066978	10066978	+	Splice_Site_SNP	SNP	T	G	G			TCGA-87-5896-01	TCGA-87-5896-01	T	T								Phase_I	Unspecified				Illumina GAIIx	g.chrX:10066978T>G	uc004csx.2	+	c.3084_splice	c.e21+2	p.Q1028_splice	WWC3_uc010nds.1_Splice_Site_SNP_p.Q692_splice|WWC3_uc010ndt.1_Splice_Site_SNP	NM_015691	NP_056506			WWC family member 3											ovary(4)	4														0.375	6.720803	6.831273	3	5	TT		KEEP	---	---	---	---	capture			Splice_Site_SNP	SNP	10066978	10066978	17987	23	T	G	G	59	59	WWC3	G	5	4
RHOXF1	158800	broad.mit.edu	36	X	119127187	119127187	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chrX:119127187G>A	uc004esk.1	-	c.546C>T	c.(544-546)GTC>GTT	p.V182V		NM_139282	NP_644811	Q8NHV9	RHXF1_HUMAN	Rhox homeobox family, member 1	182					gamete generation|multicellular organismal development|regulation of transcription, DNA-dependent|steroid hormone receptor signaling pathway	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription regulator activity				0														0.5	49.4022	49.4022	16	16	GG		KEEP	---	---	---	---	capture			Silent	SNP	119127187	119127187	13822	23	G	A	A	37	37	RHOXF1	A	1	1
RAP2C	57826	broad.mit.edu	36	X	131176017	131176017	+	Missense_Mutation	SNP	A	C	C			TCGA-87-5896-01	TCGA-87-5896-01	A	A								Phase_I	Unspecified				Illumina GAIIx	g.chrX:131176017A>C	uc004ewp.1	-	c.412T>G	c.(412-414)TGG>GGG	p.W138G	RAP2C_uc004ewo.1_Missense_Mutation_p.W72G|RAP2C_uc010nrk.1_Non-coding_Transcript|RAP2C_uc004ewq.2_Missense_Mutation_p.W138G	NM_021183	NP_067006	Q9Y3L5	RAP2C_HUMAN	RAP2C, member of RAS oncogene family	138					negative regulation of cell migration|positive regulation of protein autophosphorylation|Rap protein signal transduction|regulation of protein tyrosine kinase activity	recycling endosome membrane	GTP binding|GTPase activity			ovary(1)	1	Acute lymphoblastic leukemia(192;0.000127)													0.405797	94.654548	95.197243	28	41	AA		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	131176017	131176017	13502	23	A	C	C	8	8	RAP2C	C	4	4
F9	2158	broad.mit.edu	36	X	138470677	138470677	+	Missense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chrX:138470677G>A	uc004fas.1	+	c.835G>A	c.(835-837)GCA>ACA	p.A279T	F9_uc004fat.1_Missense_Mutation_p.A241T	NM_000133	NP_000124	P00740	FA9_HUMAN	coagulation factor IX preproprotein	279	Peptidase S1.		A -> T (in HEMB; mild).		blood coagulation, extrinsic pathway|blood coagulation, intrinsic pathway|peptidyl-glutamic acid carboxylation|post-translational protein modification|proteolysis	endoplasmic reticulum lumen|extracellular region|Golgi lumen|plasma membrane	calcium ion binding|serine-type endopeptidase activity			lung(2)|ovary(1)	3	Acute lymphoblastic leukemia(192;0.000127)				Antihemophilic Factor(DB00025)|Coagulation Factor IX(DB00100)|Heparin(DB01109)|Menadione(DB00170)									0.488636	129.618161	129.628167	43	45	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	138470677	138470677	5548	23	G	A	A	38	38	F9	A	1	1
FATE1	89885	broad.mit.edu	36	X	150641801	150641801	+	Missense_Mutation	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chrX:150641801G>A	uc004fex.1	+	c.466G>A	c.(466-468)GCC>ACC	p.A156T		NM_033085	NP_149076	Q969F0	FATE1_HUMAN	fetal and adult testis expressed transcript	156						endoplasmic reticulum|integral to membrane				ovary(1)	1	Acute lymphoblastic leukemia(192;6.56e-05)													0.516667	90.147571	90.163791	31	29	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	150641801	150641801	5929	23	G	A	A	38	38	FATE1	A	1	1
MAP7D2	256714	broad.mit.edu	36	X	19984786	19984786	+	Silent	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chrX:19984786C>T	uc010nfo.1	-	c.417G>A	c.(415-417)CAG>CAA	p.Q139Q	MAP7D2_uc004czq.1_Silent_p.Q10Q|MAP7D2_uc004czr.1_Silent_p.Q139Q|MAP7D2_uc004czs.1_Silent_p.Q95Q	NM_152780	NP_689993	Q96T17	MA7D2_HUMAN	MAP7 domain containing 2	139	Potential.									ovary(2)|breast(1)	3														0.3	24.262101	25.33496	9	21	CC		KEEP	---	---	---	---	capture			Silent	SNP	19984786	19984786	9651	23	C	T	T	28	28	MAP7D2	T	2	2
BCOR	54880	broad.mit.edu	36	X	39818237	39818237	+	Missense_Mutation	SNP	C	T	T			TCGA-87-5896-01	TCGA-87-5896-01	C	C								Phase_I	Unspecified				Illumina GAIIx	g.chrX:39818237C>T	uc004den.2	-	c.1306G>A	c.(1306-1308)GTC>ATC	p.V436I	BCOR_uc004dep.2_Missense_Mutation_p.V436I|BCOR_uc004deo.2_Missense_Mutation_p.V436I|BCOR_uc004dem.2_Missense_Mutation_p.V436I|BCOR_uc004deq.2_Missense_Mutation_p.V436I	NM_001123385	NP_001116857	Q6W2J9	BCOR_HUMAN	BCL-6 interacting corepressor isoform c	436					chromatin modification|heart development|negative regulation of bone mineralization|negative regulation of histone H3-K36 methylation|negative regulation of histone H3-K4 methylation|negative regulation of tooth mineralization|odontogenesis|palate development|protein ubiquitination|specification of axis polarity|transcription, DNA-dependent	nucleus	heat shock protein binding|histone deacetylase binding|promoter binding|transcription corepressor activity|transcription factor binding			ovary(2)|kidney(1)|central_nervous_system(1)	4														0.459459	50.171989	50.224776	17	20	CC		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	39818237	39818237	1407	23	C	T	T	19	19	BCOR	T	1	1
ITIH5L	347365	broad.mit.edu	36	X	54800598	54800598	+	Missense_Mutation	SNP	G	T	T			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chrX:54800598G>T	uc004dtj.1	-	c.2634C>A	c.(2632-2634)AAC>AAA	p.N878K		NM_198510	NP_940912	Q6UXX5	ITH5L_HUMAN	inter-alpha (globulin) inhibitor H5-like	878	Pro-rich.				hyaluronan metabolic process	extracellular region	serine-type endopeptidase inhibitor activity			lung(2)|ovary(1)|breast(1)|skin(1)	5										249				0.387755	55.209437	55.751725	19	30	GG		KEEP	---	---	---	---	capture			Missense_Mutation	SNP	54800598	54800598	8212	23	G	T	T	44	44	ITIH5L	T	3	3
ZXDA	7789	broad.mit.edu	36	X	57952050	57952050	+	Silent	SNP	G	A	A			TCGA-87-5896-01	TCGA-87-5896-01	G	G								Phase_I	Unspecified				Illumina GAIIx	g.chrX:57952050G>A	uc004dve.1	-	c.1530C>T	c.(1528-1530)TTC>TTT	p.F510F		NM_007156	NP_009087	P98168	ZXDA_HUMAN	zinc finger, X-linked, duplicated A	510	Required for interaction with ZXDC.|C2H2-type 9.				positive regulation of transcription, DNA-dependent	nucleus	C2H2 zinc finger domain binding|identical protein binding|nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(1)	1														0.4	47.192712	47.54226	16	24	GG		KEEP	---	---	---	---	capture			Silent	SNP	57952050	57952050	18855	23	G	A	A	37	37	ZXDA	A	1	1
