Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KCNMA1	3778	broad.mit.edu	37	10	79011015	79011015	+	Splice_Site	SNP	C	T	T			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr10:79011015C>T	uc001jxn.2	-	3	718	c.541_splice	c.e3-1	p.V181_splice	KCNMA1_uc001jxj.2_Splice_Site_p.V181_splice|KCNMA1_uc009xrt.1_Splice_Site|KCNMA1_uc001jxo.2_Splice_Site_p.V181_splice|KCNMA1_uc001jxm.2_Splice_Site_p.V181_splice|KCNMA1_uc001jxq.2_Splice_Site_p.V181_splice	NM_001161352	NP_001154824	Q12791	KCMA1_HUMAN	large conductance calcium-activated potassium						cellular potassium ion homeostasis|negative regulation of cell volume|platelet activation|positive regulation of apoptosis|regulation of membrane potential|response to calcium ion|response to carbon monoxide|response to hypoxia|response to osmotic stress|smooth muscle contraction involved in micturition	apical plasma membrane|caveola|integral to membrane|voltage-gated potassium channel complex	actin binding|calcium-activated potassium channel activity|large conductance calcium-activated potassium channel activity|metal ion binding|voltage-gated potassium channel activity			pancreas(2)|ovary(1)	3	all_cancers(46;0.203)|all_epithelial(25;0.00604)|Prostate(51;0.0198)		OV - Ovarian serous cystadenocarcinoma(4;0.0586)|Epithelial(14;0.081)|all cancers(16;0.183)		Bendroflumethiazide(DB00436)|Benzthiazide(DB00562)|Chlorothiazide(DB00880)|Chlorzoxazone(DB00356)|Cromoglicate(DB01003)|Cyclothiazide(DB00606)|Diazoxide(DB01119)|Enflurane(DB00228)|Hydrochlorothiazide(DB00999)|Hydroflumethiazide(DB00774)|Methyclothiazide(DB00232)|Quinethazone(DB01325)|Trichlormethiazide(DB01021)	CTAAGACAACCTGTAAAAGAA	0.398											OREG0020289	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	35	---	---	---	---	0	0	0.150653	0	0
SYNE2	23224	broad.mit.edu	37	14	64680925	64680925	+	Missense_Mutation	SNP	A	G	G			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr14:64680925A>G	uc001xgm.2	+	106	19300	c.19070A>G	c.(19069-19071)GAA>GGA	p.E6357G	SYNE2_uc001xgl.2_Missense_Mutation_p.E6357G|SYNE2_uc010apy.2_Missense_Mutation_p.E2742G|SYNE2_uc001xgn.2_Missense_Mutation_p.E1319G|SYNE2_uc001xgo.2_RNA|SYNE2_uc010aqa.2_Missense_Mutation_p.E327G|SYNE2_uc001xgq.2_Missense_Mutation_p.E722G|SYNE2_uc001xgr.2_Missense_Mutation_p.E140G|SYNE2_uc010tsi.1_5'UTR|SYNE2_uc001xgs.2_5'UTR|SYNE2_uc001xgt.2_5'Flank	NM_015180	NP_055995	Q8WXH0	SYNE2_HUMAN	spectrin repeat containing, nuclear envelope 2	6357	Cytoplasmic (Potential).				centrosome localization|cytoskeletal anchoring at nuclear membrane|nuclear migration along microfilament|positive regulation of cell migration	cytoskeleton|filopodium membrane|focal adhesion|integral to membrane|lamellipodium membrane|mitochondrial part|nuclear outer membrane|nucleoplasm|sarcoplasmic reticulum membrane|SUN-KASH complex|Z disc	actin binding|protein binding			ovary(8)|breast(4)|central_nervous_system(1)|pancreas(1)	14				all cancers(60;0.00153)|OV - Ovarian serous cystadenocarcinoma(108;0.00444)|BRCA - Breast invasive adenocarcinoma(234;0.0681)		TTGGAAGATGAAAAGGAGGCC	0.443													7	103	---	---	---	---	0	0	0.248553	0	0
SNORD115-17	100033455	broad.mit.edu	37	15	25448253	25448253	+	5'Flank	SNP	G	A	A			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr15:25448253G>A	uc001yzo.1	+						PAR4_uc001yzk.1_RNA|PAR4_uc010ayo.1_RNA|SNORD115-17_uc001yzp.1_5'Flank	NR_003311				Homo sapiens small nucleolar RNA, C/D box 115-17 (SNORD115-17), non-coding RNA.												0						TCATCCCGGCGTCCAGCCCCT	0.617													7	51	---	---	---	---	0	0	0.248553	0	0
Unknown	0	broad.mit.edu	37	15	76067987	76067987	+	Missense_Mutation	SNP	A	G	G	rs34243492	by1000genomes	TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr15:76067987A>G	uc010umm.1	+	1	94	c.17A>G	c.(16-18)CAA>CGA	p.Q6R						SubName: Full=cDNA FLJ59077, highly similar to Golgin subfamily A member 6;																		GAAGAAACTCAACAGAGTAAA	0.537													3	31	---	---	---	---	0	0	0.115264	0	0
CDH8	1006	broad.mit.edu	37	16	61687935	61687935	+	Silent	SNP	G	A	A			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr16:61687935G>A	uc002eog.1	-	12	2229	c.1977C>T	c.(1975-1977)GAC>GAT	p.D659D		NM_001796	NP_001787	P55286	CADH8_HUMAN	cadherin 8, type 2 preproprotein	659	Cytoplasmic (Potential).				adherens junction organization|cell junction assembly|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(6)|skin(2)|breast(1)	9		Ovarian(137;0.0799)|Melanoma(118;0.16)		UCEC - Uterine corpus endometrioid carcinoma (183;0.196)|Epithelial(162;0.0155)|all cancers(182;0.0305)|OV - Ovarian serous cystadenocarcinoma(108;0.0499)|BRCA - Breast invasive adenocarcinoma(181;0.249)		TTTCTCGAACGTCTTCATCAT	0.393													8	122	---	---	---	---	0	0	0.335167	0	0
ZNF235	9310	broad.mit.edu	37	19	44807571	44807571	+	Translation_Start_Site	SNP	C	A	A			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr19:44807571C>A	uc002oza.3	-	2	90	c.-13G>T	c.(-15--11)AAGGA>AATGA		ZNF235_uc002oyx.1_RNA|ZNF235_uc010eji.2_Translation_Start_Site|ZNF235_uc002ozb.3_Translation_Start_Site|ZNF235_uc010xwx.1_Translation_Start_Site	NM_004234	NP_004225	Q14590	ZN235_HUMAN	zinc finger protein 93 homolog						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(2)|large_intestine(1)	3		Prostate(69;0.0352)|all_neural(266;0.116)				TCCCCTCCTCCTTCTGGGAAA	0.413													8	92	---	---	---	---	0.00307968	0.00334748	0.278610	1	0
FAM182B	728882	broad.mit.edu	37	20	25848617	25848617	+	RNA	SNP	A	G	G			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr20:25848617A>G	uc002wvd.1	-	1		c.170T>C								Homo sapiens cDNA FLJ30282 fis, clone BRACE2002803.												0						ggcaggcctgaggctgggatg	0													2	2	---	---	---	---	0	0	0.115264	0	0
FRG1B	284802	broad.mit.edu	37	20	29624093	29624093	+	Splice_Site	SNP	G	T	T	rs75468660		TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr20:29624093G>T	uc010ztl.1	+	1	58	c.26_splice	c.e1+1	p.R9_splice	FRG1B_uc002wvm.1_Intron|FRG1B_uc010ztj.1_Intron|FRG1B_uc010gdr.1_Intron|FRG1B_uc010ztk.1_Intron					Homo sapiens cDNA FLJ32537 fis, clone SMINT2000400, highly similar to Homo sapiens FRG1 mRNA.												0						CTGATTCCAGGTGAGCTTATG	0.289													3	11	---	---	---	---	0.004672	0.00486667	0.115264	1	0
WFS1	7466	broad.mit.edu	37	4	6302918	6302918	+	Missense_Mutation	SNP	G	C	C			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr4:6302918G>C	uc003giy.2	+	8	1562	c.1396G>C	c.(1396-1398)GGC>CGC	p.G466R	WFS1_uc003gix.2_Missense_Mutation_p.G466R|WFS1_uc003giz.2_Missense_Mutation_p.G284R	NM_001145853	NP_001139325	O76024	WFS1_HUMAN	wolframin	466	Helical; (Potential).				endoplasmic reticulum calcium ion homeostasis|endoplasmic reticulum unfolded protein response|ER overload response|ER-associated protein catabolic process|glucose homeostasis|kidney development|negative regulation of neuron apoptosis|negative regulation of sequence-specific DNA binding transcription factor activity|polyubiquitinated misfolded protein transport|positive regulation of calcium ion transport|positive regulation of growth|positive regulation of protein ubiquitination|positive regulation of proteolysis|protein stabilization|renal water homeostasis|sensory perception of sound|visual perception	dendrite|integral to endoplasmic reticulum membrane	activating transcription factor binding|ATPase binding|transporter activity|ubiquitin protein ligase binding			central_nervous_system(2)	2				Colorectal(103;0.0512)		GGTCACCGCCGGCCTGCTATC	0.642													6	75	---	---	---	---	0	0	0.217242	0	0
AFM	173	broad.mit.edu	37	4	74357625	74357625	+	Missense_Mutation	SNP	T	G	G			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr4:74357625T>G	uc003hhb.2	+	8	911	c.880T>G	c.(880-882)TCT>GCT	p.S294A		NM_001133	NP_001124	P43652	AFAM_HUMAN	afamin precursor	294	Albumin 2.				vitamin transport		vitamin E binding			ovary(2)|central_nervous_system(1)	3	Breast(15;0.00102)		Epithelial(6;5.69e-05)|OV - Ovarian serous cystadenocarcinoma(6;0.000324)|all cancers(17;0.000555)|Lung(101;0.103)|LUSC - Lung squamous cell carcinoma(112;0.154)			AAAACAAGATTCTATCTCCAG	0.358													5	104	---	---	---	---	0	0	0.217242	0	0
FLOT1	10211	broad.mit.edu	37	6	30707994	30707994	+	Missense_Mutation	SNP	C	T	T			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr6:30707994C>T	uc003nrm.2	-	8	828	c.664G>A	c.(664-666)GCC>ACC	p.A222T	FLOT1_uc011dmr.1_Missense_Mutation_p.A174T	NM_005803	NP_005794	O75955	FLOT1_HUMAN	flotillin 1	222						centriolar satellite|endosome|integral to membrane|melanosome|membrane fraction					0						ATGTCATAGGCGGCCTTCTTC	0.562													4	51	---	---	---	---	0	0	0.150653	0	0
TUBBP5	643224	broad.mit.edu	37	9	141070969	141070969	+	Silent	SNP	A	G	G			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr9:141070969A>G	uc004com.2	+	4	633	c.372A>G	c.(370-372)GCA>GCG	p.A124A	TUBBP5_uc010ncq.2_3'UTR					RecName: Full=Putative tubulin beta-4q chain;												0						TAGAAAACGCAGATGAGACCT	0.517													5	43	---	---	---	---	0	0	0.184627	0	0
EIF1AX	1964	broad.mit.edu	37	X	20156731	20156731	+	Missense_Mutation	SNP	C	T	T			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chrX:20156731C>T	uc004czt.2	-	2	234	c.26G>A	c.(25-27)GGT>GAT	p.G9D	SCARNA9L_uc010nfp.2_5'Flank	NM_001412	NP_001403	P47813	IF1AX_HUMAN	X-linked eukaryotic translation initiation	9						cytosol	translation initiation factor activity			ovary(1)	1						TCTGTTTTTACCTCCTTTACC	0.313													15	56	---	---	---	---	0	0	0.500413	0	0
Unknown	0	broad.mit.edu	37	11	5079715	5079716	+	IGR	DEL	AA	-	-			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr11:5079715_5079716delAA								OR52J3 (11033 upstream) : OR52E2 (165 downstream)																							actctgtctcaaaaaaaaaaaa	0.149													2	4	---	---	---	---					
C12orf71	728858	broad.mit.edu	37	12	27234923	27234923	+	Frame_Shift_Del	DEL	C	-	-			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr12:27234923delC	uc001rhq.2	-	1	533	c.494delG	c.(493-495)GGCfs	p.G165fs		NM_001080406	NP_001073875	A8MTZ7	CL071_HUMAN	hypothetical protein LOC728858	165											0						CGGAGGGGAGCCGCTGGATAG	0.423													2	4	---	---	---	---					
BACH1	571	broad.mit.edu	37	21	30699014	30699014	+	Frame_Shift_Del	DEL	A	-	-			TCGA-EL-A3CO-01A-11D-A19J-08	TCGA-EL-A3CO-10A-01D-A19M-08									Somatic	Phase_I	Capture				Illumina GAIIx	ba1f48c1-8d38-4a91-ba08-a8ecb63cac88	bc492b5b-036e-4452-ac96-4fa312ce29ef	g.chr21:30699014delA	uc002ynj.2	+	3	984	c.869delA	c.(868-870)GAAfs	p.E290fs	BACH1_uc002ynk.2_Frame_Shift_Del_p.E290fs|BACH1_uc002ynl.2_RNA	NM_001186	NP_001177	O14867	BACH1_HUMAN	BTB and CNC homology 1 transcription factor	290						nucleus	protein dimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			ovary(1)|liver(1)	2						GAACCTGAAGAAACGAAGAAA	0.428													13	121	---	---	---	---					
