Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU
NPM1	4869	genome.wustl.edu	36	5	170770152	170770153	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	-	-			-	-	Verified	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	5	170770152	170770153	0	TCTG	INS	NPM1	NM_002520	human	genbank	54_36p	1	validated	frame_shift_ins	c.863_864	p.W288fs	1.000:1.000	NULL	Nucleoplasmin;HMMPfam_Nucleoplasmin;Nucleoplasmin-like	-	NA
SOS1	6654	genome.wustl.edu	36	2	39103418	39103418	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C			C	C	Unknown	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	2	39103418	39103418	C	T	SNP	SOS1	NM_005633	human	genbank	54_36p	-1	reviewed	missense	c.1655	p.R552K	1.000	NULL	HMMPfam_RhoGEF,HMMSmart_SM00325,superfamily_DBL homology domain (DH-domain),HMMPfam_RasGEF_N,HMMSmart_SM00229,HMMPfam_PH,HMMSmart_SM00233,HMMPfam_RasGEF,HMMSmart_SM00147,HMMPfam_Histone,superfamily_Ras GEF,superfamily_Histone-fold,PatternScan_RASGEF,superfamily_PH domain-like	-	no_errors
EPB41L5	57669	genome.wustl.edu	36	2	120565690	120565690	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	G	G			G	G	Unknown	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	2	120565690	120565690	G	A	SNP	EPB41L5	NM_020909	human	genbank	54_36p	+1	provisional	missense	c.1133	p.R378Q	0.995	HMMPfam_FA	HMMPfam_FA,HMMPfam_FERM_N,HMMPfam_FERM_C,PatternScan_FERM_1,PatternScan_FERM_2,HMMPfam_FERM_M,superfamily_Second domain of FERM,HMMSmart_SM00295,superfamily_PH domain-like,superfamily_Ubiquitin-like	-	no_errors
CADM2	253559	genome.wustl.edu	36	3	86197523	86197523	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C			C	C	Unknown	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	3	86197523	86197523	C	T	SNP	CADM2	NM_153184	human	genbank	54_36p	+1	validated	missense	c.1148	p.T383M	1.000	NULL	HMMSmart_4.1m,HMMSmart_IGc2,HMMSmart_IG,HMMPfam_V-set,HMMPfam_ig,HMMPfam_C2-set_2,superfamily_SSF48726	-	no_errors
LAMA5	3911	genome.wustl.edu	36	20	60333829	60333829	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C			C	C	Unknown	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	20	60333829	60333829	C	T	SNP	LAMA5	NM_005560	human	genbank	54_36p	-1	reviewed	missense	c.5467	p.A1823T	0.013	HMMPfam_Laminin_B	HMMPfam_Laminin_B,PatternScan_TNFR_NGFR_1,HMMSmart_SM00282,HMMPfam_Laminin_EGF,HMMSmart_SM00180,PatternScan_EGF_LAM_1,HMMSmart_SM00181,HMMPfam_Laminin_N,HMMSmart_SM00136,superfamily_Galactose-binding domain-like,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_I,HMMPfam_Laminin_II,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,HMMSmart_SM00281,superfamily_EGF/Laminin	-	no_errors
LIPC	3990	genome.wustl.edu	36	15	56643171	56643171	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	G	G			G	G	Unknown	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	15	56643171	56643171	G	A	SNP	LIPC	NM_000236	human	genbank	54_36p	+1	reviewed	missense	c.1345	p.V449I	0.038	HMMPfam_PLAT,HMMSmart_SM00308,superfamily_Lipase/lipooxygenase domain (PLAT/LH2 domain)	HMMPfam_PLAT,HMMSmart_SM00308,PatternScan_LIPASE_SER,superfamily_Lipase/lipooxygenase domain (PLAT/LH2 domain),HMMPfam_Lipase,superfamily_alpha/beta-Hydrolases	-	no_errors
ZNF462	58499	genome.wustl.edu	36	9	108731052	108731052	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C			C	C	Unknown	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	9	108731052	108731052	C	T	SNP	ZNF462	NM_021224	human	genbank	54_36p	+1	validated	missense	c.5038	p.R1680C	1.000	PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers,superfamily_beta-sandwich domain of Sec23/24	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers,superfamily_beta-sandwich domain of Sec23/24	-	no_errors
CALB2	794	genome.wustl.edu	36	16	69977001	69977001	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C			C	C	Unknown	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	16	69977001	69977001	C	T	SNP	CALB2	NM_007088	human	genbank	54_36p	+1	reviewed	missense	c.554	p.T185M	0.999	NULL	HMMSmart_EFh,PatternScan_EF_HAND_1,HMMPfam_efhand,superfamily_SSF47473	-	no_errors
IDH1	3417	genome.wustl.edu	36	2	208821358	208821358	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	G	G			G	G	Verified	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	2	208821358	208821358	G	C	SNP	IDH1	NM_005896	human	genbank	54_36p	-1	reviewed	missense	c.394	p.R132G	1	HMMPfam_Iso_dh	HMMPfam_Iso_dh;superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	NA
ANKRD24	170961	genome.wustl.edu	36	19	4137441	4137441	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AB-2990-03A-01D-0739-09	TCGA-AB-2990-11A-01D-0739-09	C	C			C	C	Unknown	Valid	Somatic		WGS	Illumina_Capture			Illumina GAIIx	19	4137441	4137441	C	T	SNP	ANKRD24	NM_133475	human	genbank	54_36p	+1	provisional	nonsense	c.19	p.R7*	0.921	NULL	HMMPfam_Ank,HMMSmart_SM00248,superfamily_Ankyrin repeat	-	no_errors
