Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
OR4A15	81328	broad.mit.edu	37	11	55135389	55135389	+	Silent	SNP	T	C	C			TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr11:55135389T>C	uc010rif.1	+	1	30	c.30T>C	c.(28-30)TTT>TTC	p.F10F		NM_001005275	NP_001005275	Q8NGL6	O4A15_HUMAN	olfactory receptor, family 4, subfamily A,	10	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|skin(1)	2						ATCTCAAATTTATCACTGACC	0.413000													4	78	---	---	---	---	0	0	0.009096	0	0
CASC5	57082	broad.mit.edu	37	15	40913253	40913253	+	Missense_Mutation	SNP	A	G	G			TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr15:40913253A>G	uc010bbs.1	+	11	1030	c.869A>G	c.(868-870)GAT>GGT	p.D290G	CASC5_uc010ucq.1_Missense_Mutation_p.D114G|CASC5_uc001zme.2_Missense_Mutation_p.D264G|CASC5_uc010bbt.1_Missense_Mutation_p.D264G	NM_170589	NP_733468	Q8NG31	CASC5_HUMAN	cancer susceptibility candidate 5 isoform 1	290	Interaction with BUB1 and BUB1B.				acrosome assembly|attachment of spindle microtubules to kinetochore|cell division|CenH3-containing nucleosome assembly at centromere|mitotic prometaphase|spindle assembly checkpoint	acrosomal vesicle|condensed chromosome kinetochore|cytosol|nucleoplasm	protein binding			breast(3)|central_nervous_system(1)|skin(1)	5		all_cancers(109;2.03e-18)|all_epithelial(112;4.26e-15)|Lung NSC(122;1.12e-10)|all_lung(180;2.59e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0822)|Colorectal(260;0.0946)		GBM - Glioblastoma multiforme(113;4.99e-05)|BRCA - Breast invasive adenocarcinoma(123;0.0861)|COAD - Colon adenocarcinoma(120;0.211)		CTTAAGGAAGATGAAAATAAC	0.363000													6	93	---	---	---	---	0	0	0.021553	0	0
NSD1	64324	broad.mit.edu	37	5	176687001	176687001	+	Missense_Mutation	SNP	C	T	T			TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr5:176687001C>T	uc003mfr.3	+	14	5116	c.4978C>T	c.(4978-4980)CGC>TGC	p.R1660C	NSD1_uc003mft.3_Missense_Mutation_p.R1391C|NSD1_uc003mfs.1_Missense_Mutation_p.R1557C|NSD1_uc011dfx.1_Missense_Mutation_p.R1308C	NM_022455	NP_071900	Q96L73	NSD1_HUMAN	nuclear receptor binding SET domain protein 1	1660					negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleus	androgen receptor binding|chromatin binding|estrogen receptor binding|histone methyltransferase activity (H3-K36 specific)|histone methyltransferase activity (H4-K20 specific)|ligand-dependent nuclear receptor binding|retinoid X receptor binding|thyroid hormone receptor binding|transcription corepressor activity|zinc ion binding			ovary(2)|kidney(1)	3	all_cancers(89;1.57e-05)|Renal(175;0.000269)|Lung NSC(126;0.00111)|all_lung(126;0.002)	all_neural(177;0.00409)|Medulloblastoma(196;0.00498)|all_hematologic(541;0.21)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)|Epithelial(233;0.198)	Kidney(146;0.235)		TCGGTTGATGCGCTGTGTCCG	0.403000			T	NUP98	AML		Sotos Syndrome		Beckwith-Wiedemann_syndrome|Sotos_syndrome|Weaver_syndrome	HNSCC(47;0.14)			5	194	---	---	---	---	0	0	0.021553	0	0
Unknown	0	broad.mit.edu	37	1	37045879	37045880	+	IGR	INS	-	AC	AC	rs143316746	by1000genomes	TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr1:37045879_37045880insAC								CSF3R (97370 upstream) : GRIK3 (215248 downstream)																							TACACATTAGTacacacacaca	0.163													5	3	---	---	---	---					
LOC200030	200030	broad.mit.edu	37	1	148349431	148349432	+	5'Flank	INS	-	G	G	rs67020224		TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr1:148349431_148349432insG	uc001eqf.2	-						LOC200030_uc001eqe.2_5'Flank|LOC200030_uc001eqg.2_5'Flank|NBPF14_uc009wkf.1_5'Flank|uc001erd.3_5'Flank|uc001erc.3_5'Flank|uc010paj.1_5'Flank|uc010pav.1_5'Flank|uc010paw.1_5'Flank	NM_017940	NP_060410	Q86T75	NBPFB_HUMAN	hypothetical protein LOC55672							cytoplasm					0						GGGCTGACACTGGGGGGCCAGA	0.559													5	11	---	---	---	---					
Unknown	0	broad.mit.edu	37	16	27088704	27088705	+	IGR	INS	-	CTTT	CTTT	rs143025532	by1000genomes	TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr16:27088704_27088705insCTTT								C16orf82 (8218 upstream) : JMJD5 (126102 downstream)																							ctccttccttccttccttcctt	0.000													3	3	---	---	---	---					
Unknown	0	broad.mit.edu	37	19	3131446	3131446	+	IGR	DEL	C	-	-	rs66993077		TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr19:3131446delC								GNA11 (9994 upstream) : GNA15 (4745 downstream)																							aaaaaaaaaacaaaaaaaaaa	0.348													7	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	2	114552156	114552159	+	IGR	DEL	GAAG	-	-			TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr2:114552156_114552159delGAAG								SLC35F5 (37756 upstream) : ACTR3 (95378 downstream)																							ggaagggaaagaaggaaggaagga	0.000													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	2	217474994	217474994	+	IGR	DEL	T	-	-	rs71401155		TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr2:217474994delT								RPL37A (108808 upstream) : IGFBP2 (23133 downstream)																							tctttctttcttttttttttt	0.368													3	3	---	---	---	---					
Unknown	0	broad.mit.edu	37	4	165981409	165981410	+	Frame_Shift_Ins	INS	-	C	C			TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr4:165981409_165981410insC	uc011cjl.1	+	1	1110_1111	c.1110_1111insC	c.(1108-1113)CTTCCCfs	p.L370fs		NM_001105575	NP_001099045			tripartite motif-containing 75																		AAGATTCTCTTCCCACAAAGGC	0.485													67	195	---	---	---	---					
Unknown	0	broad.mit.edu	37	5	37909585	37909586	+	IGR	DEL	AA	-	-	rs2973078		TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr5:37909585_37909586delAA								GDNF (69803 upstream) : EGFLAM (348947 downstream)																							acacacacacaATACACTGTTT	0.317													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	7	65976419	65976420	+	IGR	INS	-	A	A			TCGA-BJ-A0ZJ-01A-11D-A10S-08	TCGA-BJ-A0ZJ-10A-01D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	50437cd5-7611-4021-bba6-5a6597c8d024	219fccf2-bfd4-412a-bf0c-e865392d8b4e	g.chr7:65976419_65976420insA								NCRNA00174 (111024 upstream) : LOC493754 (17026 downstream)																							ccatctcgaacaaaaaaaaaaa	0.243													4	5	---	---	---	---					
