Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ATP13A2	23400	broad.mit.edu	37	1	17326791	17326791	+	Missense_Mutation	SNP	C	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr1:17326791C>T	uc001baa.2	-	10	1047	c.857G>A	c.(856-858)AGG>AAG	p.R286K	ATP13A2_uc001bab.2_Missense_Mutation_p.R281K|ATP13A2_uc001bac.2_Missense_Mutation_p.R281K|ATP13A2_uc009vpa.1_5'UTR|ATP13A2_uc001bad.1_5'UTR	NM_022089	NP_071372	Q9NQ11	AT132_HUMAN	ATPase type 13A2 isoform 1	286	Cytoplasmic (Potential).				ATP biosynthetic process|cation transport	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|metal ion binding			skin(2)|ovary(1)|central_nervous_system(1)	4		Colorectal(325;0.000147)|Breast(348;0.00104)|Renal(390;0.00145)|Lung NSC(340;0.00566)|all_lung(284;0.00797)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0646)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00462)|COAD - Colon adenocarcinoma(227;1.11e-05)|BRCA - Breast invasive adenocarcinoma(304;1.99e-05)|Kidney(64;0.000171)|KIRC - Kidney renal clear cell carcinoma(64;0.00258)|STAD - Stomach adenocarcinoma(196;0.00645)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.182)		GACCATGTCCCTTAGAGTCTG	0.692000													3	30					0	0	0.115264	0	0
Unknown	0	broad.mit.edu	37	12	92018	92018	+	Missense_Mutation	SNP	T	C	C			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr12:92018T>C	uc010sdi.1	-	2	320	c.292A>G	c.(292-294)AGT>GGT	p.S98G	uc010sdj.1_RNA					SubName: Full=DEAD/H box polypeptide 11 like 11;																		GACTCCACACTCTCCTGGGTT	0.592000													5	35					0	0	0.184627	0	0
PRB3	5544	broad.mit.edu	37	12	11420475	11420475	+	Silent	SNP	A	G	G			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr12:11420475A>G	uc001qzs.2	-	3	746	c.708T>C	c.(706-708)CCT>CCC	p.P236P	PRB4_uc001qzf.1_Intron	NM_006249	NP_006240	Q04118	PRB3_HUMAN	proline-rich protein BstNI subfamily 3	236	9.|10 X 21 AA tandem repeats of [RH]-P-G-K- P-[EQ]-G-[PQS]-P-[PS]-Q-[GE]-G-N-[QK]- [SP]-[QR]-[GR]-P-P-P.|Pro-rich.					extracellular region	Gram-negative bacterial cell surface binding			skin(1)	1			OV - Ovarian serous cystadenocarcinoma(49;0.201)			GGGGACCTTGAGGTTTGTTGC	0.617000													6	24					0	0	0.248553	0	0
POLR3B	55703	broad.mit.edu	37	12	106820975	106820975	+	Missense_Mutation	SNP	C	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr12:106820975C>T	uc001tlp.2	+	13	1324	c.1102C>T	c.(1102-1104)CTT>TTT	p.L368F	POLR3B_uc001tlq.2_Missense_Mutation_p.L310F	NM_018082	NP_060552	Q9NW08	RPC2_HUMAN	DNA-directed RNA polymerase III B isoform 1	368					innate immune response|positive regulation of innate immune response|positive regulation of interferon-beta production|response to virus|termination of RNA polymerase III transcription|transcription elongation from RNA polymerase III promoter	nucleoplasm	DNA binding|DNA-directed RNA polymerase activity|metal ion binding|ribonucleoside binding			ovary(1)|central_nervous_system(1)	2						TTTTTTTTAGCTTTTATCTCT	0.274000													6	21					0	0	0.411799	0	0
Unknown	0	broad.mit.edu	37	15	20496657	20496657	+	RNA	SNP	C	T	T	rs7180374	by1000genomes	TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr15:20496657C>T	uc001ytf.1	+	6		c.710C>T								full-length cDNA clone CS0DI026YN18 of Placenta Cot 25-normalized of Homo sapiens (human).																		GACCACAAAGCGCCCGGCTGT	0.438000													6	94					0	0	0.217242	0	0
LOC646214	646214	broad.mit.edu	37	15	21937168	21937168	+	RNA	SNP	C	T	T	rs12185110		TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr15:21937168C>T	uc010tzj.1	-	1		c.3572G>A				NR_027053				Homo sapiens mRNA for p21-activated kinase 2 variant protein.												0						AGGTATTCCACGACCACAAAC	0.408000													15	272					0	0	0.479597	0	0
LOC646214	646214	broad.mit.edu	37	15	21937819	21937819	+	RNA	SNP	G	C	C	rs4984133		TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr15:21937819G>C	uc010tzj.1	-	1		c.2921C>G				NR_027053				Homo sapiens mRNA for p21-activated kinase 2 variant protein.												0						TAGTAATCGAGCCCAGTGTTC	0.453000													16	410					0	0	0.500413	0	0
WHAMML1	339005	broad.mit.edu	37	15	23205108	23205108	+	RNA	SNP	C	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr15:23205108C>T	uc001yvg.2	-	2		c.687G>A			WHAMML1_uc010ayc.2_RNA|WHAMML1_uc010ayd.2_RNA|WHAMML1_uc010aye.1_RNA	NR_003521				Homo sapiens mRNA; cDNA DKFZp313L2232 (from clone DKFZp313L2232).												0						GTGGTTGCCACGGTAACTAAT	0.393000													4	49					0	0	0.150653	0	0
GLG1	2734	broad.mit.edu	37	16	74640687	74640687	+	Silent	SNP	T	C	C			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr16:74640687T>C	uc002fcy.3	-	1	356	c.306A>G	c.(304-306)GGA>GGG	p.G102G	GLG1_uc002fcx.2_Silent_p.G102G|GLG1_uc002fcw.3_Silent_p.G102G|GLG1_uc002fcz.3_5'UTR	NM_001145667	NP_001139139	Q92896	GSLG1_HUMAN	golgi apparatus protein 1 isoform 3	102	Extracellular (Potential).					Golgi membrane|integral to membrane	receptor binding			ovary(1)|breast(1)	2						CCCCCGCTCCTCCCCGCCGGG	0.527000													7	44					0	0	0.361761	0	0
GNAS	2778	broad.mit.edu	37	20	57484420	57484420	+	Missense_Mutation	SNP	C	T	T	rs11554273		TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr20:57484420C>T	uc002xzw.2	+	8	2815	c.2530C>T	c.(2530-2532)CGT>TGT	p.R844C	GNAS_uc002xzt.2_3'UTR|GNAS_uc010gjq.2_Missense_Mutation_p.R142C|GNAS_uc002xzx.2_Missense_Mutation_p.R142C|GNAS_uc010gjr.2_Missense_Mutation_p.R92C|GNAS_uc002xzy.2_Missense_Mutation_p.R127C|GNAS_uc002yaa.2_Missense_Mutation_p.R187C|GNAS_uc010zzt.1_Missense_Mutation_p.R202C|GNAS_uc002yab.2_Intron|GNAS_uc002yad.2_Missense_Mutation_p.R92C|GNAS_uc002yae.2_Missense_Mutation_p.R126C	NM_080425	NP_536350	P63092	GNAS2_HUMAN	GNAS complex locus XLas	201	GTP (By similarity).		R -> L (in non-MAS endocrine tumors).|R -> S (in AIMAH, pituitary tumor and polyostotic fibrous dysplasia).|R -> H (in MAS, somatotrophinoma and AIMAH).|R -> G (in MAS).		activation of adenylate cyclase activity|cellular response to glucagon stimulus|energy reserve metabolic process|G-protein coupled receptor protein signaling pathway|intracellular transport|platelet activation|regulation of insulin secretion|sensory perception of smell|transmembrane transport|water transport	heterotrimeric G-protein complex|intrinsic to membrane|trans-Golgi network membrane	adenylate cyclase activity|GTP binding|GTPase activity|guanyl-nucleotide exchange factor activity|identical protein binding|signal transducer activity	p.R201C(182)|p.R201S(5)		pituitary(201)|thyroid(35)|ovary(15)|adrenal_gland(9)|liver(7)|large_intestine(5)|parathyroid(5)|kidney(5)|haematopoietic_and_lymphoid_tissue(3)|lung(2)|testis(1)|stomach(1)|small_intestine(1)|autonomic_ganglia(1)|pancreas(1)	292	all_lung(29;0.0104)		BRCA - Breast invasive adenocarcinoma(13;2.19e-08)|Colorectal(105;0.109)			GCTTCGCTGCCGTGTCCTGAC	0.428000			Mis		pituitary adenoma		McCune-Albright syndrome; pseudohypoparathyroidism|type IA		3-Methylglutaconic_Aciduria_and_Myelodysplasia|McCune-Albright_syndrome|Mazabraud_syndrome	TSP Lung(22;0.16)			10	199					0	0	0.335167	0	0
CYP2D7P1	1564	broad.mit.edu	37	22	42538870	42538870	+	Missense_Mutation	SNP	A	C	C	rs2982057	by1000genomes	TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr22:42538870A>C	uc003bci.2	-	3	475	c.94T>G	c.(94-96)TCG>GCG	p.S32A	CYP2D7P1_uc003bcg.2_5'Flank|CYP2D7P1_uc003bch.2_5'Flank|CYP2D7P1_uc010gyv.2_Intron|CYP2D7P1_uc010gyw.2_RNA|CYP2D7P1_uc010gyx.1_Missense_Mutation_p.S32A	NR_002570				SubName: Full=Cytochrome P450 2D6;          EC=1.14.14.1;												0						CCATAGCGCGACAGGAACACC	0.687000													4	76					0	0	0.184627	0	0
MST1P2	11209	broad.mit.edu	37	1	16975913	16975918	+	RNA	DEL	CCTGTT	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr1:16975913_16975918delCCTGTT	uc010och.1	+	11		c.1935_1940delCCTGTT			MST1P2_uc001azl.3_RNA|MST1P2_uc009vox.2_RNA|MST1P2_uc001azm.3_RNA	NR_027504				Homo sapiens cDNA FLJ43241 fis, clone HEART1000010, weakly  similar to Hepatocyte growth factor-like protein precursor.												0						GGTTGGGCACCCTGTTCCAGAACCCA	0.578													8	220	---	---	---	---					
GBP5	115362	broad.mit.edu	37	1	89732166	89732166	+	Frame_Shift_Del	DEL	T	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr1:89732166delT	uc001dnc.2	-	7	1268	c.731delA	c.(730-732)AAGfs	p.K244fs	GBP5_uc001dnd.2_Frame_Shift_Del_p.K244fs|GBP5_uc001dne.1_Frame_Shift_Del_p.K244fs	NM_052942	NP_443174	Q96PP8	GBP5_HUMAN	guanylate-binding protein 5	244						plasma membrane	GTP binding|GTPase activity			ovary(1)	1				all cancers(265;0.00784)|Epithelial(280;0.0286)		TTGGGCAAGCTTTTTTTGGTG	0.388													7	592	---	---	---	---					
SYCP1	6847	broad.mit.edu	37	1	115537600	115537601	+	Frame_Shift_Ins	INS	-	A	A			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr1:115537600_115537601insA	uc001efr.2	+	32	3100_3101	c.2891_2892insA	c.(2890-2892)AGAfs	p.R964fs	SYCP1_uc010owt.1_RNA|SYCP1_uc001efq.2_Frame_Shift_Ins_p.R964fs|SYCP1_uc009wgw.2_Frame_Shift_Ins_p.R939fs	NM_003176	NP_003167	Q15431	SYCP1_HUMAN	synaptonemal complex protein 1	964	Arg/Lys-rich (basic).				cell division|reciprocal meiotic recombination|spermatogenesis|synaptonemal complex assembly		DNA binding			skin(1)	1	Lung SC(450;0.211)	all_cancers(81;8.65e-08)|all_epithelial(167;3.32e-07)|all_lung(203;6.55e-06)|Lung NSC(69;1.11e-05)|Acute lymphoblastic leukemia(138;0.221)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		AAAATGGATAGAAAAAAAAAAC	0.356													9	222	---	---	---	---					
HAX1	10456	broad.mit.edu	37	1	154245864	154245866	+	In_Frame_Del	DEL	GAA	-	-	rs11556342		TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr1:154245864_154245866delGAA	uc001fes.2	+	2	267_269	c.106_108delGAA	c.(106-108)GAAdel	p.E40del	HAX1_uc001fet.2_Intron|HAX1_uc010peo.1_In_Frame_Del_p.E40del|HAX1_uc009wou.2_5'UTR|HAX1_uc009wov.2_In_Frame_Del_p.E14del	NM_006118	NP_006109	O00165	HAX1_HUMAN	HCLS1 associated protein X-1 isoform a	40	Asp/Glu-rich (highly acidic).|Required for localization in mitochondria (By similarity).					actin cytoskeleton|cytoplasmic membrane-bounded vesicle|lamellipodium|mitochondrion|nuclear membrane|sarcoplasmic reticulum|soluble fraction	interleukin-1 binding|protein N-terminus binding				0	all_lung(78;2.62e-30)|Lung NSC(65;3.94e-28)|Hepatocellular(266;0.0877)		LUSC - Lung squamous cell carcinoma(543;0.185)			TGATGATGAGGAAGAAGAAGAAG	0.522									Kostmann_syndrome				7	224	---	---	---	---					
PRG4	10216	broad.mit.edu	37	1	186276374	186276376	+	In_Frame_Del	DEL	CCA	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr1:186276374_186276376delCCA	uc001gru.3	+	7	1574_1576	c.1523_1525delCCA	c.(1522-1527)CCCACC>CCC	p.T511del	PRG4_uc001grt.3_In_Frame_Del_p.T470del|PRG4_uc009wyl.2_In_Frame_Del_p.T418del|PRG4_uc009wym.2_In_Frame_Del_p.T377del|PRG4_uc010poo.1_Intron	NM_005807	NP_005798	Q92954	PRG4_HUMAN	proteoglycan 4 isoform A	511	59 X 8 AA repeats of K-X-P-X-P-T-T-X.|21.				cell proliferation|immune response	extracellular region	polysaccharide binding|protein binding|scavenger receptor activity			skin(1)	1						GAGCCTGCACCCACCACCACCAA	0.645													7	598	---	---	---	---					
RPS10P7	376693	broad.mit.edu	37	1	201489731	201489731	+	RNA	DEL	G	-	-	rs4915234	by1000genomes	TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr1:201489731delG	uc009wzz.1	+	1		c.1901delG								Homo sapiens cDNA FLJ31028 fis, clone HLUNG2000570, weakly similar to 40S RIBOSOMAL PROTEIN S10.												0						AAAAAaaaaagaaagaaagct	0.184													5	7	---	---	---	---					
KIAA1462	57608	broad.mit.edu	37	10	30316501	30316503	+	In_Frame_Del	DEL	CTG	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr10:30316501_30316503delCTG	uc001iux.2	-	2	2633_2635	c.2574_2576delCAG	c.(2572-2577)AGCAGT>AGT	p.858_859SS>S	KIAA1462_uc001iuy.2_Intron|KIAA1462_uc001iuz.2_In_Frame_Del_p.720_721SS>S|KIAA1462_uc009xle.1_In_Frame_Del_p.858_859SS>S	NM_020848	NP_065899	Q9P266	K1462_HUMAN	hypothetical protein LOC57608	858_859	Ser-rich.									ovary(4)	4						ACTCTCCTCActgctgctgctgc	0.463													10	275	---	---	---	---					
UVRAG	7405	broad.mit.edu	37	11	75694430	75694431	+	Splice_Site	INS	-	A	A			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr11:75694430_75694431insA	uc001oxc.2	+	8	941	c.700_splice	c.e8-1	p.K234_splice	UVRAG_uc010rrw.1_Splice_Site_p.K133_splice|UVRAG_uc001oxd.2_Splice_Site|UVRAG_uc010rrx.1_5'UTR|UVRAG_uc009yuh.1_Splice_Site	NM_003369	NP_003360	Q9P2Y5	UVRAG_HUMAN	UV radiation resistance associated						DNA repair|positive regulation of autophagy	early endosome|late endosome|lysosome	protein binding			skin(4)|lung(2)	6						TATTTATTTAGAAAAAAAAAAG	0.302													7	95	---	---	---	---					
ASCL1	429	broad.mit.edu	37	12	103352172	103352174	+	In_Frame_Del	DEL	GCA	-	-	rs72405287		TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr12:103352172_103352174delGCA	uc001tjr.3	+	1	721_723	c.150_152delGCA	c.(148-153)GCGCAG>GCG	p.Q62del		NM_004316	NP_004307	P50553	ASCL1_HUMAN	achaete-scute complex homolog 1	62	Poly-Gln.			Q -> QQQ (in Ref. 1).	cerebral cortex GABAergic interneuron differentiation|negative regulation of apoptosis|negative regulation of neuron differentiation|negative regulation of transcription, DNA-dependent|noradrenergic neuron fate commitment|Notch signaling pathway|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|response to retinoic acid|sympathetic nervous system development	nucleus	bHLH transcription factor binding|E-box binding|sequence-specific DNA binding transcription factor activity|transcription factor binding transcription factor activity				0						cgcagagcgcgcagcagcagcag	0.443													3	6	---	---	---	---					
MLEC	9761	broad.mit.edu	37	12	121134166	121134168	+	In_Frame_Del	DEL	GAA	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr12:121134166_121134168delGAA	uc001tyy.1	+	5	848_850	c.697_699delGAA	c.(697-699)GAAdel	p.E238del		NM_014730	NP_055545	Q14165	MLEC_HUMAN	malectin precursor	238	Poly-Glu.|Lumenal (Potential).				post-translational protein modification|protein folding|protein N-linked glycosylation via asparagine	endoplasmic reticulum membrane|integral to membrane	carbohydrate binding			ovary(1)	1						gaaagaagaggaagaagaagaag	0.404													15	586	---	---	---	---					
ADAM6	8755	broad.mit.edu	37	14	106774086	106774087	+	Splice_Site	INS	-	AGTAATACACGGCA	AGTAATACACGGCA			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr14:106774086_106774087insAGTAATACACGGCA	uc010tyt.1	-	430		c.15674_splice	c.e430+1							Parts of antibodies, mostly variable regions.												0						GCCTCTTGCACGTGTCCTCAGC	0.550													9	29	---	---	---	---					
ADAM6	8755	broad.mit.edu	37	14	106877821	106877826	+	RNA	DEL	CTACTG	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr14:106877821_106877826delCTACTG	uc010tyt.1	-	277		c.11273_11278delCAGTAG			uc010tyu.1_In_Frame_Del_p.42_44SSS>S					Parts of antibodies, mostly variable regions.												0						GTAGTAACTACTACTGCTGATGGAGC	0.607													9	335	---	---	---	---					
SPATA5L1	79029	broad.mit.edu	37	15	45710840	45710841	+	Frame_Shift_Ins	INS	-	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr15:45710840_45710841insT	uc001zve.2	+	7	2163_2164	c.2054_2055insT	c.(2053-2055)TGTfs	p.C685fs	SPATA5L1_uc001zvf.2_RNA	NM_024063	NP_076968	Q9BVQ7	SPA5L_HUMAN	spermatogenesis associated 5-like 1	685						cytoplasm	ATP binding|nucleoside-triphosphatase activity			ovary(3)|skin(1)	4		Lung NSC(122;8.3e-05)|all_lung(180;0.000547)|Melanoma(134;0.0417)		all cancers(107;7.31e-17)|GBM - Glioblastoma multiforme(94;6.28e-07)		GCAGAAACCTGTTTTTTTTCTG	0.356													8	227	---	---	---	---					
NOX5	79400	broad.mit.edu	37	15	69331226	69331226	+	Frame_Shift_Del	DEL	T	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr15:69331226delT	uc002ars.1	+	9	1421	c.1401delT	c.(1399-1401)CCTfs	p.P467fs	NOX5_uc002arp.1_Frame_Shift_Del_p.P449fs|NOX5_uc002arq.1_Frame_Shift_Del_p.P421fs|NOX5_uc010bid.1_Frame_Shift_Del_p.P432fs|NOX5_uc002arr.1_Frame_Shift_Del_p.P439fs|NOX5_uc010bie.1_Frame_Shift_Del_p.P267fs|NOX5_uc010bif.1_Intron	NM_024505	NP_078781	Q96PH1	NOX5_HUMAN	NADPH oxidase, EF-hand calcium binding domain 5	467	FAD-binding FR-type.|Cytoplasmic (Potential).|C-terminal catalytic region.				angiogenesis|angiogenesis|cytokine secretion|cytokinesis|electron transport chain|endothelial cell proliferation|induction of apoptosis|positive regulation of reactive oxygen species metabolic process|regulation of fusion of sperm to egg plasma membrane|regulation of proton transport|superoxide anion generation	endoplasmic reticulum|endoplasmic reticulum|integral to membrane	calcium ion binding|electron carrier activity|flavin adenine dinucleotide binding|heme binding|hydrogen ion channel activity|NADP binding|superoxide-generating NADPH oxidase activity			breast(1)|pancreas(1)	2						AGCGGCCCCCTTTTTTTCACT	0.537													10	576	---	---	---	---					
TNRC6A	27327	broad.mit.edu	37	16	24807240	24807240	+	Frame_Shift_Del	DEL	A	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr16:24807240delA	uc002dmm.2	+	9	3655	c.3541delA	c.(3541-3543)AAAfs	p.K1181fs	TNRC6A_uc010bxs.2_Frame_Shift_Del_p.K928fs|TNRC6A_uc010vcc.1_Frame_Shift_Del_p.K928fs|TNRC6A_uc002dmn.2_Frame_Shift_Del_p.K928fs|TNRC6A_uc002dmo.2_Frame_Shift_Del_p.K869fs	NM_014494	NP_055309	Q8NDV7	TNR6A_HUMAN	trinucleotide repeat containing 6A	1181	Sufficient for interaction with EIF2C1 and EIF2C4.				negative regulation of translation involved in gene silencing by miRNA	cytoplasmic mRNA processing body|micro-ribonucleoprotein complex	nucleotide binding|RNA binding			ovary(2)	2				GBM - Glioblastoma multiforme(48;0.0394)		TCTGAGTGGCAAAAAAAGGAG	0.224													12	586	---	---	---	---					
TERF2IP	54386	broad.mit.edu	37	16	75690204	75690206	+	In_Frame_Del	DEL	GAA	-	-	rs140846731		TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr16:75690204_75690206delGAA	uc002fet.1	+	3	992_994	c.895_897delGAA	c.(895-897)GAAdel	p.E304del		NM_018975	NP_061848	Q9NYB0	TE2IP_HUMAN	telomeric repeat binding factor 2, interacting	304	Asp/Glu-rich (acidic).				negative regulation of DNA recombination at telomere|negative regulation of telomere maintenance|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of NF-kappaB transcription factor activity|protection from non-homologous end joining at telomere|protein localization to chromosome, telomeric region|regulation of double-strand break repair via homologous recombination|telomere maintenance via telomerase|transcription, DNA-dependent	cytoplasm|nuclear telomere cap complex|nucleoplasm	DNA binding|protein binding			central_nervous_system(1)	1						TGATgaggaggaagaagaagaag	0.369													7	306	---	---	---	---					
ADAMTS18	170692	broad.mit.edu	37	16	77334227	77334228	+	Frame_Shift_Ins	INS	-	G	G	rs148849944	by1000genomes	TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr16:77334227_77334228insG	uc002ffc.3	-	17	3025_3026	c.2606_2607insC	c.(2605-2607)CCAfs	p.P869fs	ADAMTS18_uc010chc.1_Frame_Shift_Ins_p.P457fs|ADAMTS18_uc002ffe.1_Frame_Shift_Ins_p.P565fs	NM_199355	NP_955387	Q8TE60	ATS18_HUMAN	ADAM metallopeptidase with thrombospondin type 1	869	Spacer.				proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			large_intestine(4)|lung(4)|kidney(4)|skin(3)|breast(1)|ovary(1)|pancreas(1)	18						TTTTTGTGGCTGGTGGAGTTCC	0.460													8	309	---	---	---	---					
ANKRD11	29123	broad.mit.edu	37	16	89349640	89349641	+	Frame_Shift_Ins	INS	-	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr16:89349640_89349641insT	uc002fmx.1	-	9	3770_3771	c.3309_3310insA	c.(3307-3312)AAAGATfs	p.K1103fs	ANKRD11_uc002fmy.1_Frame_Shift_Ins_p.K1103fs|ANKRD11_uc002fnc.1_Frame_Shift_Ins_p.K1103fs|ANKRD11_uc002fnb.1_Frame_Shift_Ins_p.K1060fs	NM_013275	NP_037407	Q6UB99	ANR11_HUMAN	ankyrin repeat domain 11	1103_1104	Lys-rich.					nucleus				ovary(4)|large_intestine(1)|central_nervous_system(1)	6		all_hematologic(23;0.00824)|Colorectal(91;0.0475)		Epithelial(1;5.33e-11)|all cancers(4;2.6e-09)|OV - Ovarian serous cystadenocarcinoma(4;2.29e-07)|BRCA - Breast invasive adenocarcinoma(80;0.0142)		TTCTTGTCATCTTTTTTTTCAG	0.465													8	587	---	---	---	---					
COIL	8161	broad.mit.edu	37	17	55028117	55028118	+	Frame_Shift_Ins	INS	-	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr17:55028117_55028118insT	uc002iuu.2	-	2	516_517	c.485_486insA	c.(484-486)AACfs	p.N162fs		NM_004645	NP_004636	P38432	COIL_HUMAN	coilin	162						Cajal body|nucleolus	protein C-terminus binding			ovary(1)	1	Breast(9;6.15e-08)					TTTTTCTCTTGTTTTTTTTGCT	0.366													15	445	---	---	---	---					
FHOD3	80206	broad.mit.edu	37	18	34261459	34261460	+	Frame_Shift_Del	DEL	AG	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr18:34261459_34261460delAG	uc002kzt.1	+	12	1468_1469	c.1371_1372delAG	c.(1369-1374)GCAGAGfs	p.A457fs	FHOD3_uc002kzr.1_Frame_Shift_Del_p.A457fs|FHOD3_uc002kzs.1_Frame_Shift_Del_p.A457fs|FHOD3_uc010dmz.1_Frame_Shift_Del_p.A172fs	NM_025135	NP_079411	Q2V2M9	FHOD3_HUMAN	formin homology 2 domain containing 3	457_458	Potential.				actin cytoskeleton organization	cytoplasm|cytoskeleton	actin binding			skin(3)|large_intestine(2)|breast(2)|ovary(1)	8		all_epithelial(2;0.0181)|Colorectal(2;0.0195)				CACTGGCAGCAGAGAGAGAGAG	0.460													13	273	---	---	---	---					
TMEM131	23505	broad.mit.edu	37	2	98427639	98427639	+	Frame_Shift_Del	DEL	T	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr2:98427639delT	uc002syh.3	-	18	2149	c.1920delA	c.(1918-1920)AAAfs	p.K640fs		NM_015348	NP_056163	Q92545	TM131_HUMAN	RW1 protein	640						integral to membrane				ovary(4)|central_nervous_system(2)	6						TCCCCTCTAATTTTTTTGCAG	0.393													11	860	---	---	---	---					
DSTN	11034	broad.mit.edu	37	20	17581679	17581680	+	Frame_Shift_Ins	INS	-	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr20:17581679_17581680insT	uc002wpr.2	+	2	555_556	c.300_301insT	c.(298-303)ATGTTTfs	p.M100fs	DSTN_uc002wpq.2_Frame_Shift_Ins_p.M83fs|DSTN_uc010gck.2_Frame_Shift_Ins_p.M83fs	NM_006870	NP_006861	P60981	DEST_HUMAN	destrin isoform a	100_101	ADF-H.				actin filament severing|actin polymerization or depolymerization		actin binding			large_intestine(1)|skin(1)	2						AAGAGTTGATGTTTTTTTTGTG	0.356													10	288	---	---	---	---					
ARFGAP3	26286	broad.mit.edu	37	22	43213780	43213780	+	Frame_Shift_Del	DEL	T	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr22:43213780delT	uc003bdd.2	-	10	1116	c.896delA	c.(895-897)AATfs	p.N299fs	ARFGAP3_uc010gzf.2_Frame_Shift_Del_p.N255fs|ARFGAP3_uc011apu.1_Frame_Shift_Del_p.N227fs	NM_014570	NP_055385	Q9NP61	ARFG3_HUMAN	ADP-ribosylation factor GTPase activating	299					intracellular protein transport|protein secretion|regulation of ARF GTPase activity|vesicle-mediated transport	cytosol|Golgi membrane	ARF GTPase activator activity|protein transporter activity|zinc ion binding			breast(1)	1						TGAGTCAACATTTTTTTTGCC	0.224													10	574	---	---	---	---					
GABRG1	2565	broad.mit.edu	37	4	46060358	46060358	+	Frame_Shift_Del	DEL	A	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr4:46060358delA	uc003gxb.2	-	7	944	c.792delT	c.(790-792)TTTfs	p.F264fs		NM_173536	NP_775807	Q8N1C3	GBRG1_HUMAN	gamma-aminobutyric acid A receptor, gamma 1	264	Extracellular (Probable).				gamma-aminobutyric acid signaling pathway	cell junction|chloride channel complex|postsynaptic membrane	chloride channel activity|extracellular ligand-gated ion channel activity			ovary(2)	2				Lung(65;0.106)|LUSC - Lung squamous cell carcinoma(721;0.23)		TGCTCAGGTCAAAAAAAATTG	0.294													11	271	---	---	---	---					
UTP3	57050	broad.mit.edu	37	4	71554620	71554622	+	In_Frame_Del	DEL	GAG	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr4:71554620_71554622delGAG	uc003hfo.2	+	1	425_427	c.226_228delGAG	c.(226-228)GAGdel	p.E81del		NM_020368	NP_065101	Q9NQZ2	SAS10_HUMAN	UTP3, small subunit processome component	81	Glu-rich.				brain development|chromatin modification|gene silencing	nucleolus					0			Lung(101;0.235)			ggaggatggcgaggaggaggagg	0.291													8	162	---	---	---	---					
CDS1	1040	broad.mit.edu	37	4	85556474	85556475	+	Frame_Shift_Ins	INS	-	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr4:85556474_85556475insT	uc011ccv.1	+	8	1278_1279	c.780_781insT	c.(778-783)GGATTTfs	p.G260fs	CDS1_uc010ike.1_Frame_Shift_Ins_p.G64fs	NM_001263	NP_001254	Q92903	CDS1_HUMAN	CDP-diacylglycerol synthase 1	260_261					signal transduction|visual perception	endoplasmic reticulum membrane|integral to membrane	diacylglycerol cholinephosphotransferase activity|phosphatidate cytidylyltransferase activity			large_intestine(2)|ovary(1)|breast(1)	4		Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.00101)		ACCTTTTTGGATTTTTTTTTGG	0.307													9	376	---	---	---	---					
ADAD1	132612	broad.mit.edu	37	4	123302211	123302211	+	Frame_Shift_Del	DEL	A	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr4:123302211delA	uc003ieo.2	+	4	469	c.237delA	c.(235-237)CCAfs	p.P79fs	ADAD1_uc003iep.2_Frame_Shift_Del_p.P79fs|ADAD1_uc003ieq.2_Frame_Shift_Del_p.P61fs	NM_139243	NP_640336	Q96M93	ADAD1_HUMAN	adenosine deaminase domain containing 1	79					multicellular organismal development|RNA processing	nucleus	adenosine deaminase activity|double-stranded RNA binding				0						TCCTTCCTCCAAAAAAAATAC	0.358													8	297	---	---	---	---					
MSH3	4437	broad.mit.edu	37	5	79950742	79950750	+	In_Frame_Del	DEL	CCCCCAGCT	-	-	rs3045983		TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr5:79950742_79950750delCCCCCAGCT	uc003kgz.2	+	1	449_457	c.196_204delCCCCCAGCT	c.(196-204)CCCCCAGCTdel	p.PPA66del	DHFR_uc011ctl.1_5'Flank|DHFR_uc011ctm.1_5'Flank|DHFR_uc010jap.1_5'Flank|DHFR_uc003kgx.1_In_Frame_Del_p.11_14GAGG>G|DHFR_uc003kgy.1_5'UTR	NM_002439	NP_002430	P20585	MSH3_HUMAN	mutS homolog 3	66_68					maintenance of DNA repeat elements|meiotic mismatch repair|negative regulation of DNA recombination|positive regulation of helicase activity|reciprocal meiotic recombination|somatic recombination of immunoglobulin gene segments	MutSbeta complex|nuclear chromosome	ATP binding|DNA-dependent ATPase activity|double-strand/single-strand DNA junction binding|enzyme binding|loop DNA binding|Y-form DNA binding			lung(2)|ovary(1)|breast(1)	4		Lung NSC(167;0.00479)|all_lung(232;0.00507)|Ovarian(174;0.0261)|Breast(144;0.244)		OV - Ovarian serous cystadenocarcinoma(54;2.38e-45)|Epithelial(54;1.58e-38)|all cancers(79;4.93e-33)		gCCCCCAGCGCCCCCAGCTCCCGCCTTCC	0.598								MMR					10	18	---	---	---	---					
GABBR1	2550	broad.mit.edu	37	6	29573436	29573438	+	In_Frame_Del	DEL	CAG	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr6:29573436_29573438delCAG	uc003nmt.3	-	20	2683_2685	c.2347_2349delCTG	c.(2347-2349)CTGdel	p.L783del	GABBR1_uc003nmp.3_In_Frame_Del_p.L666del|GABBR1_uc003nms.3_In_Frame_Del_p.L666del|GABBR1_uc003nmu.3_In_Frame_Del_p.L721del|GABBR1_uc011dlr.1_In_Frame_Del_p.L606del	NM_001470	NP_001461	Q9UBS5	GABR1_HUMAN	gamma-aminobutyric acid (GABA) B receptor 1	783	Helical; Name=5; (Potential).				gamma-aminobutyric acid signaling pathway|negative regulation of adenylate cyclase activity|synaptic transmission	cell junction|extracellular region|integral to plasma membrane|postsynaptic membrane	G-protein coupled receptor activity|GABA-B receptor activity			ovary(5)|liver(1)|skin(1)	7					Baclofen(DB00181)|Progabide(DB00837)	GGAAGATTCCCAGCAGCAGCAGC	0.512													7	290	---	---	---	---					
GABRR2	2570	broad.mit.edu	37	6	89975427	89975429	+	In_Frame_Del	DEL	AAG	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr6:89975427_89975429delAAG	uc003pnb.2	-	7	875_877	c.867_869delCTT	c.(865-870)TTCTTG>TTG	p.F289del	GABRR2_uc011dzx.1_In_Frame_Del_p.F165del	NM_002043	NP_002034	P28476	GBRR2_HUMAN	gamma-aminobutyric acid (GABA) receptor, rho 2	289	Helical; (Potential).				synaptic transmission	cell junction|chloride channel complex|integral to plasma membrane|postsynaptic membrane	chloride channel activity|extracellular ligand-gated ion channel activity|GABA-A receptor activity				0		all_cancers(76;1.67e-09)|Prostate(29;1.16e-10)|Acute lymphoblastic leukemia(125;1.49e-10)|all_hematologic(105;7.77e-07)|all_epithelial(107;2.51e-05)|Lung NSC(302;0.238)		BRCA - Breast invasive adenocarcinoma(108;0.0158)		TGTTTGGAGCAAGAAGAAGAAGA	0.517													10	265	---	---	---	---					
ICA1	3382	broad.mit.edu	37	7	8198250	8198251	+	Frame_Shift_Ins	INS	-	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr7:8198250_8198251insT	uc003srm.2	-	7	678_679	c.611_612insA	c.(610-612)AACfs	p.N204fs	ICA1_uc010ktr.2_Frame_Shift_Ins_p.N204fs|ICA1_uc003srl.2_Frame_Shift_Ins_p.N192fs|ICA1_uc003srn.3_Frame_Shift_Ins_p.N130fs|ICA1_uc003srp.3_Frame_Shift_Ins_p.N203fs|ICA1_uc010kts.2_RNA|ICA1_uc003srq.2_Frame_Shift_Ins_p.N204fs|ICA1_uc003srr.2_Frame_Shift_Ins_p.N203fs|ICA1_uc003sro.3_Frame_Shift_Ins_p.N204fs|ICA1_uc011jxg.1_Frame_Shift_Ins_p.N204fs|ICA1_uc003srs.1_Frame_Shift_Ins_p.N204fs	NM_022307	NP_071682	Q05084	ICA69_HUMAN	islet cell autoantigen 1	204	AH.				neurotransmitter transport	cell junction|cytosol|Golgi membrane|nucleus|secretory granule membrane|synaptic vesicle membrane|transport vesicle membrane				central_nervous_system(1)	1		Ovarian(82;0.0612)		UCEC - Uterine corpus endometrioid carcinoma (126;0.246)		ATTTGTCAAAGTTTTTTTTTGC	0.376													8	247	---	---	---	---					
RAB11FIP1	80223	broad.mit.edu	37	8	37728932	37728933	+	Frame_Shift_Ins	INS	-	T	T			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr8:37728932_37728933insT	uc003xkm.1	-	4	3431_3432	c.3387_3388insA	c.(3385-3390)AAAGCCfs	p.K1129fs	RAB11FIP1_uc010lvz.1_Intron|RAB11FIP1_uc003xkn.1_Intron|RAB11FIP1_uc003xkl.1_Frame_Shift_Ins_p.K458fs|RAB11FIP1_uc003xko.1_Frame_Shift_Ins_p.K458fs|RAB11FIP1_uc003xkp.1_Intron	NM_001002814	NP_001002814	Q6WKZ4	RFIP1_HUMAN	RAB11 family interacting protein 1 isoform 3	1129_1130					protein transport	centrosome|phagocytic vesicle membrane|recycling endosome	protein binding			ovary(1)|central_nervous_system(1)|skin(1)	3		Lung NSC(58;0.118)|all_lung(54;0.195)	LUSC - Lung squamous cell carcinoma(8;3.62e-11)			TCTGCTGTGGCTTTTTTTTGAG	0.545											OREG0018713	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	7	628	---	---	---	---					
PKHD1L1	93035	broad.mit.edu	37	8	110455173	110455174	+	Splice_Site	INS	-	G	G			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr8:110455173_110455174insG	uc003yne.2	+	36	4498	c.4394_splice	c.e36-1	p.G1465_splice		NM_177531	NP_803875	Q86WI1	PKHL1_HUMAN	fibrocystin L precursor						immune response	cytosol|extracellular space|integral to membrane	receptor activity			ovary(9)|central_nervous_system(2)|large_intestine(1)|breast(1)|pancreas(1)	14			OV - Ovarian serous cystadenocarcinoma(57;9.88e-13)			ATTTTATGGCAGGTTCATTTTC	0.322										HNSCC(38;0.096)			7	304	---	---	---	---					
PRDM12	59335	broad.mit.edu	37	9	133543701	133543702	+	Splice_Site	DEL	GT	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chr9:133543701_133543702delGT	uc004bzt.1	+	3	630	c.570_splice	c.e3+1	p.E190_splice		NM_021619	NP_067632	Q9H4Q4	PRD12_HUMAN	PR domain containing 12						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		all_hematologic(13;0.0433)|Acute lymphoblastic leukemia(5;0.0534)		OV - Ovarian serous cystadenocarcinoma(145;0.000344)		GGCCATTGAGGTGTGTGTGTGT	0.594													11	219	---	---	---	---					
PRRG1	5638	broad.mit.edu	37	X	37312611	37312611	+	Frame_Shift_Del	DEL	C	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chrX:37312611delC	uc004ddn.2	+	5	647	c.394delC	c.(394-396)CCCfs	p.P132fs	PRRG1_uc004ddo.2_Frame_Shift_Del_p.P132fs	NM_000950	NP_000941	O14668	TMG1_HUMAN	proline rich Gla (G-carboxyglutamic acid) 1	132	Cytoplasmic (Potential).|Poly-Pro.					extracellular region|integral to plasma membrane	calcium ion binding			ovary(1)|breast(1)	2						TATCACCCCACCCCCCCCACC	0.488													7	333	---	---	---	---					
FAM120C	54954	broad.mit.edu	37	X	54209302	54209303	+	In_Frame_Ins	INS	-	GGCGGC	GGCGGC			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chrX:54209302_54209303insGGCGGC	uc004dsz.3	-	1	412_413	c.329_330insGCCGCC	c.(328-330)CCC>CCGCCGCCC	p.110_110P>PPP	FAM120C_uc011moh.1_In_Frame_Ins_p.110_110P>PPP|FAM120C_uc004dta.2_In_Frame_Ins_p.110_110P>PPP	NM_017848	NP_060318	Q9NX05	F120C_HUMAN	hypothetical protein LOC54954	110										ovary(1)|central_nervous_system(1)	2						GCAGCTGAGGGGGCGGCGGCGG	0.748													5	8	---	---	---	---					
NAP1L2	4674	broad.mit.edu	37	X	72433664	72433666	+	In_Frame_Del	DEL	TCC	-	-			TCGA-F2-7276-01A-11D-2154-08	TCGA-F2-7276-10A-01D-2154-08									Somatic	Phase_I	Capture				Illumina GAIIx	dc12b1a6-7f32-40c4-950c-e99392389a8e	b1a1bd8b-59e5-47d3-8a7f-65495eaacb3f	g.chrX:72433664_72433666delTCC	uc004ebi.2	-	1	1019_1021	c.663_665delGGA	c.(661-666)GAGGAC>GAC	p.E221del	NAP1L2_uc011mqj.1_In_Frame_Del_p.E79del	NM_021963	NP_068798	Q9ULW6	NP1L2_HUMAN	nucleosome assembly protein 1-like 2	221	Glu-rich (acidic).				nucleosome assembly	chromatin assembly complex				lung(1)	1	Renal(35;0.156)					CTCAATGTCGtcctcctcctcct	0.330													7	108	---	---	---	---					
