Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FOXE3	2301	broad.mit.edu	37	1	47882415	47882415	+	Missense_Mutation	SNP	A	C	C			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr1:47882415A>C	uc001crk.2	+	1	672	c.428A>C	c.(427-429)AAC>ACC	p.N143T		NM_012186	NP_036318	Q13461	FOXE3_HUMAN	forkhead box E3	143	Fork-head.				cell migration|embryonic organ morphogenesis|enteric nervous system development|hair follicle morphogenesis|hard palate development|lens morphogenesis in camera-type eye|pattern specification process|positive regulation of epithelial cell proliferation|positive regulation of transcription from RNA polymerase II promoter|regulation of sequence-specific DNA binding transcription factor activity|soft palate development|thyroid gland development|thyroid hormone generation	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding				0				READ - Rectum adenocarcinoma(2;0.0908)		GGCAAGGGCAACTACTGGACG	0.627000													26	54					0	0	0.693898	0	0
PEA15	8682	broad.mit.edu	37	1	160181403	160181403	+	Silent	SNP	C	A	A			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr1:160181403C>A	uc001fvk.2	+	2	259	c.69C>A	c.(67-69)CTC>CTA	p.L23L	uc001fvj.1_5'Flank|PEA15_uc001fvl.2_Silent_p.L44L|PEA15_uc001fvm.2_Silent_p.L23L	NM_003768	NP_003759	Q15121	PEA15_HUMAN	phosphoprotein enriched in astrocytes 15	23	DED.				anti-apoptosis|apoptosis|carbohydrate transport|negative regulation of glucose import	cytoplasm|microtubule associated complex	protein binding				0	all_cancers(52;3.11e-18)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.111)			TAGAACAGCTCAAGTCGGCCT	0.542000													13	77					1.3612e-06	1.42926e-06	0.479597	1	0
VIM	7431	broad.mit.edu	37	10	17276732	17276732	+	Missense_Mutation	SNP	C	G	G			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr10:17276732C>G	uc001iou.2	+	6	1336	c.923C>G	c.(922-924)GCC>GGC	p.A308G	VIM_uc001iov.1_Missense_Mutation_p.A308G|VIM_uc001iow.1_RNA|VIM_uc001iox.1_Missense_Mutation_p.A308G|VIM_uc001ioy.1_Missense_Mutation_p.A308G|VIM_uc001ioz.1_RNA|VIM_uc001ipb.1_RNA|VIM_uc009xjv.1_Intron|VIM_uc001ipc.1_Missense_Mutation_p.A308G	NM_003380	NP_003371	P08670	VIME_HUMAN	vimentin	308	Rod.|Coil 2.				cellular component disassembly involved in apoptosis|cellular component movement|interspecies interaction between organisms|muscle filament sliding	cytosol|intermediate filament	protein C-terminus binding|structural constituent of cytoskeleton			large_intestine(1)|lung(1)|ovary(1)|pancreas(1)	4						AACAATGACGCCCTGCGCCAG	0.512000													15	90					0	0	0.500413	0	0
LOC642826	642826	broad.mit.edu	37	10	47207813	47207813	+	RNA	SNP	T	C	C			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr10:47207813T>C	uc001jei.2	-	12		c.1586A>G			uc009xnf.2_Missense_Mutation_p.H132R					Homo sapiens cDNA, FLJ99065.												0						TTTACTTACATGGTTTGTACA	0.294000													3	17					0	0	0.115264	0	0
C11orf49	79096	broad.mit.edu	37	11	47074069	47074069	+	Missense_Mutation	SNP	G	T	T			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr11:47074069G>T	uc001ndp.2	+	3	386	c.280G>T	c.(280-282)GAT>TAT	p.D94Y	C11orf49_uc001nds.2_Missense_Mutation_p.D94Y|C11orf49_uc001ndq.2_Missense_Mutation_p.D94Y|C11orf49_uc001ndr.2_Missense_Mutation_p.D94Y|C11orf49_uc010rgx.1_5'UTR|C11orf49_uc010rgy.1_Missense_Mutation_p.D85Y|C11orf49_uc010rgz.1_Intron	NM_024113	NP_077018	Q9H6J7	CK049_HUMAN	hypothetical protein LOC79096 isoform 3	94											0						CAAAAATGGCGGTAAGTCTTC	0.289000													39	51					7.05121e-23	7.59361e-23	0.853193	1	0
ARHGEF17	9828	broad.mit.edu	37	11	73020470	73020470	+	Missense_Mutation	SNP	G	A	A			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr11:73020470G>A	uc001otu.2	+	1	808	c.787G>A	c.(787-789)GGA>AGA	p.G263R		NM_014786	NP_055601	Q96PE2	ARHGH_HUMAN	Rho guanine nucleotide exchange factor (GEF) 17	263					actin cytoskeleton organization|apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol	Rho guanyl-nucleotide exchange factor activity				0						GCAGCTGCCTGGAGCCCAGAG	0.721000													18	16					0	0	0.592651	0	0
MYO7A	4647	broad.mit.edu	37	11	76890090	76890090	+	Splice_Site	SNP	G	T	T			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr11:76890090G>T	uc001oyb.2	+	20	2555	c.2283_splice	c.e20-1	p.R761_splice	MYO7A_uc010rsl.1_Splice_Site_p.R761_splice|MYO7A_uc010rsm.1_Splice_Site_p.R750_splice|MYO7A_uc001oyc.2_Splice_Site_p.R761_splice|MYO7A_uc001oyd.2_Splice_Site_p.R101_splice|MYO7A_uc009yus.1_5'Flank|MYO7A_uc009yut.1_5'Flank	NM_000260	NP_000251	Q13402	MYO7A_HUMAN	myosin VIIA isoform 1						actin filament-based movement|equilibrioception|lysosome organization|sensory perception of sound|visual perception	cytosol|lysosomal membrane|myosin complex|photoreceptor inner segment|photoreceptor outer segment|synapse	actin binding|ATP binding|calmodulin binding|microfilament motor activity			ovary(3)|breast(1)	4						TGCTGTTTCAGGTCTAACTTT	0.453000													9	7					1.12685e-05	1.15433e-05	0.307466	1	0
MED17	9440	broad.mit.edu	37	11	93542943	93542943	+	Missense_Mutation	SNP	C	A	A			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr11:93542943C>A	uc001pem.3	+	11	1920	c.1645C>A	c.(1645-1647)CTG>ATG	p.L549M		NM_004268	NP_004259	Q9NVC6	MED17_HUMAN	mediator complex subunit 17	549					androgen receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter	mediator complex|transcription factor complex	ligand-dependent nuclear receptor transcription coactivator activity|receptor activity|RNA polymerase II transcription cofactor activity|thyroid hormone receptor binding|vitamin D receptor binding			ovary(1)	1		Acute lymphoblastic leukemia(157;2.31e-05)|all_hematologic(158;0.00824)				CTGGCAAGTACTGAGCTTCAG	0.493000													66	77					2.3441e-25	2.59085e-25	0.870114	1	0
VPS26B	112936	broad.mit.edu	37	11	134115448	134115448	+	Silent	SNP	C	T	T			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr11:134115448C>T	uc001qhe.2	+	6	1431	c.975C>T	c.(973-975)ACC>ACT	p.T325T		NM_052875	NP_443107	Q4G0F5	VP26B_HUMAN	vacuolar protein sorting 26 homolog B	325					protein transport|vacuolar transport	cytosol|retromer complex					0	all_hematologic(175;0.127)	all_cancers(12;1.1e-21)|all_epithelial(12;3.77e-16)|all_lung(97;1.19e-05)|Lung NSC(97;2.76e-05)|Breast(109;0.000182)|Medulloblastoma(222;0.0245)|all_neural(223;0.0505)|Esophageal squamous(93;0.0559)		Epithelial(10;2.43e-10)|all cancers(11;2.94e-09)|BRCA - Breast invasive adenocarcinoma(10;9.57e-09)|OV - Ovarian serous cystadenocarcinoma(99;0.00164)|Lung(977;0.216)		AGGTGCGGACCCCCAGCCAGC	0.652000													17	14					0	0	0.520397	0	0
RPAP3	79657	broad.mit.edu	37	12	48080648	48080648	+	Missense_Mutation	SNP	C	T	T			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr12:48080648C>T	uc001rpr.2	-	9	1023	c.907G>A	c.(907-909)GAA>AAA	p.E303K	RPAP3_uc010slk.1_Missense_Mutation_p.E144K|RPAP3_uc001rps.2_Missense_Mutation_p.E303K	NM_024604	NP_078880	Q9H6T3	RPAP3_HUMAN	RNA polymerase II associated protein 3 isoform	303	TPR 5.						binding			ovary(1)	1	Lung SC(27;0.192)					GTATAGCATTCAATTGCTCTT	0.348000													38	30					0	0	0.840704	0	0
PTGDR	5729	broad.mit.edu	37	14	52734893	52734894	+	Missense_Mutation	DNP	CT	AG	AG			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr14:52734893_52734894CT>AG	uc001wzq.2	+	1	463_464	c.361_362CT>AG	c.(361-363)CTG>AGG	p.L121R		NM_000953	NP_000944	Q13258	PD2R_HUMAN	prostaglandin D2 receptor	121	Helical; Name=3; (Potential).					integral to membrane|plasma membrane	prostaglandin D receptor activity|protein binding			ovary(1)|lung(1)|central_nervous_system(1)|skin(1)	4	Breast(41;0.0639)|all_epithelial(31;0.0887)				Nedocromil(DB00716)	CTCCTCGACACTGCAACTCCTG	0.629000													70	122					0	0	0.115264	0	0
PLA2G4F	255189	broad.mit.edu	37	15	42442584	42442584	+	Missense_Mutation	SNP	A	G	G			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr15:42442584A>G	uc001zoz.2	-	9	935	c.872T>C	c.(871-873)GTG>GCG	p.V291A	PLA2G4F_uc001zoy.2_5'Flank|PLA2G4F_uc010bcr.2_Missense_Mutation_p.V42A|PLA2G4F_uc001zpa.2_Missense_Mutation_p.V42A|PLA2G4F_uc010bcs.2_Missense_Mutation_p.V78A	NM_213600	NP_998765	Q68DD2	PA24F_HUMAN	phospholipase A2, group IVF	291					phospholipid catabolic process	cytosol|lysosomal membrane	metal ion binding|phospholipase A2 activity			ovary(4)	4		all_cancers(109;4.82e-12)|all_epithelial(112;5.64e-11)|Lung NSC(122;2.17e-07)|all_lung(180;8.79e-07)|Melanoma(134;0.091)		GBM - Glioblastoma multiforme(94;8.97e-07)		CCCCAGGGCCACAGAACACTG	0.652000													15	11					0	0	0.457914	0	0
ADAMTS7	11173	broad.mit.edu	37	15	79059041	79059041	+	Missense_Mutation	SNP	T	C	C			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr15:79059041T>C	uc002bej.3	-	19	3423	c.3212A>G	c.(3211-3213)AAT>AGT	p.N1071S	ADAMTS7_uc010und.1_3'UTR	NM_014272	NP_055087	Q9UKP4	ATS7_HUMAN	ADAM metallopeptidase with thrombospondin type 1	1071					proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding				0						CTCGTGGAAATTGATGAAATT	0.617000													4	46					0	0	0.150653	0	0
C15orf42	90381	broad.mit.edu	37	15	90129030	90129030	+	Missense_Mutation	SNP	G	A	A			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr15:90129030G>A	uc002boe.2	+	4	1268	c.1268G>A	c.(1267-1269)CGC>CAC	p.R423H		NM_152259	NP_689472	Q7Z2Z1	TICRR_HUMAN	leucine-rich repeat kinase 1	423					cell cycle|DNA repair|DNA replication|formation of translation preinitiation complex|G2/M transition checkpoint|mitotic cell cycle DNA replication checkpoint|regulation of DNA-dependent DNA replication initiation|response to ionizing radiation	nucleus	chromatin binding|protein binding			ovary(4)|central_nervous_system(2)|skin(1)	7	Lung NSC(78;0.0237)|all_lung(78;0.0478)		BRCA - Breast invasive adenocarcinoma(143;0.128)			ACTGTGTGCCGCACCAAGGAG	0.542000													5	57					0	0	0.217242	0	0
ZC3H18	124245	broad.mit.edu	37	16	88697571	88697571	+	Missense_Mutation	SNP	C	T	T			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr16:88697571C>T	uc002fky.2	+	18	2926	c.2726C>T	c.(2725-2727)GCC>GTC	p.A909V	ZC3H18_uc010voz.1_Missense_Mutation_p.A933V|ZC3H18_uc010chw.2_RNA|ZC3H18_uc002fkz.2_Missense_Mutation_p.A179V	NM_144604	NP_653205	Q86VM9	ZCH18_HUMAN	zinc finger CCCH-type containing 18	909						nucleus	nucleic acid binding|zinc ion binding			skin(1)	1				BRCA - Breast invasive adenocarcinoma(80;0.0542)		CCCGGCAAAGCCTCGGATCCC	0.642000													4	101					0	0	0.184627	0	0
KPNB1	3837	broad.mit.edu	37	17	45727756	45727756	+	Silent	SNP	G	A	A			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr17:45727756G>A	uc002ilt.1	+	2	381	c.45G>A	c.(43-45)CGG>CGA	p.R15R	KPNB1_uc010wkw.1_5'Flank	NM_002265	NP_002256	Q14974	IMB1_HUMAN	karyopherin beta 1	15					DNA fragmentation involved in apoptotic nuclear change|NLS-bearing substrate import into nucleus|protein import into nucleus, translocation|ribosomal protein import into nucleus|viral genome transport in host cell|viral infectious cycle	cytosol|nuclear pore|nucleoplasm	nuclear localization sequence binding|protein domain specific binding|zinc ion binding			ovary(1)|pancreas(1)|skin(1)	3						CCCTAGATCGGCTGGAGCTGG	0.716000													3	32					0	0	0.115264	0	0
APCDD1	147495	broad.mit.edu	37	18	10487950	10487950	+	Missense_Mutation	SNP	G	A	A	rs112875590		TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr18:10487950G>A	uc002kom.3	+	5	1814	c.1460G>A	c.(1459-1461)CGG>CAG	p.R487Q		NM_153000	NP_694545	Q8J025	APCD1_HUMAN	adenomatosis polyposis coli down-regulated 1	487	Extracellular (Potential).				hair follicle development|negative regulation of Wnt receptor signaling pathway|Wnt receptor signaling pathway	integral to plasma membrane	Wnt-protein binding				0				READ - Rectum adenocarcinoma(15;0.08)		CTGTATGGCCGGGCCCCTGGG	0.592000													34	87					0	0	0.812448	0	0
DSG4	147409	broad.mit.edu	37	18	28980927	28980927	+	Missense_Mutation	SNP	A	T	T			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr18:28980927A>T	uc002kwq.2	+	10	1496	c.1361A>T	c.(1360-1362)AAG>ATG	p.K454M	DSG4_uc002kwr.2_Missense_Mutation_p.K454M	NM_177986	NP_817123	Q86SJ6	DSG4_HUMAN	desmoglein 4 isoform 2 preproprotein	454	Extracellular (Potential).|Cadherin 4.				homophilic cell adhesion	desmosome|integral to membrane	calcium ion binding			central_nervous_system(5)|ovary(3)	8			OV - Ovarian serous cystadenocarcinoma(10;0.00504)			GAATTTGATAAGAAGTCAAAA	0.289000													29	36					0	0	0.779181	0	0
WDR18	57418	broad.mit.edu	37	19	992048	992048	+	Missense_Mutation	SNP	A	G	G			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr19:992048A>G	uc002lqm.1	+	8	1051	c.1025A>G	c.(1024-1026)CAC>CGC	p.H342R	WDR18_uc002lqn.1_RNA|WDR18_uc010drx.1_Missense_Mutation_p.H305R|WDR18_uc010dry.1_Missense_Mutation_p.H342R	NM_024100	NP_077005	Q9BV38	WDR18_HUMAN	WD repeat domain 18	342										skin(1)	1		Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;1.04e-05)|all_lung(49;1.53e-05)|Breast(49;9.42e-05)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		TTCAACAAGCACCTGCTGGGC	0.716000													14	8					0	0	0.457914	0	0
NLRP5	126206	broad.mit.edu	37	19	56511120	56511120	+	Missense_Mutation	SNP	G	A	A			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr19:56511120G>A	uc002qmj.2	+	1	29	c.29G>A	c.(28-30)GGA>GAA	p.G10E	NLRP5_uc002qmi.2_Missense_Mutation_p.G10E	NM_153447	NP_703148	P59047	NALP5_HUMAN	NACHT, LRR and PYD containing protein 5	10						mitochondrion|nucleolus	ATP binding			ovary(3)|skin(2)|kidney(1)|central_nervous_system(1)	7		Colorectal(82;3.46e-05)|Ovarian(87;0.0481)|Renal(1328;0.157)		GBM - Glioblastoma multiforme(193;0.0326)		cttgaacttggagctgcTGCT	0.254000													26	161					0	0	0.740014	0	0
PROM2	150696	broad.mit.edu	37	2	95941238	95941238	+	Missense_Mutation	SNP	G	A	A			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr2:95941238G>A	uc002suh.1	+	2	407	c.274G>A	c.(274-276)GCC>ACC	p.A92T	PROM2_uc002sui.2_Missense_Mutation_p.A92T|PROM2_uc002suj.2_5'UTR|PROM2_uc002suk.2_Missense_Mutation_p.A92T|PROM2_uc002sul.2_5'UTR	NM_144707	NP_653308	Q8N271	PROM2_HUMAN	prominin 2 precursor	92	Extracellular (Potential).					apical plasma membrane|basolateral plasma membrane|cilium membrane|integral to membrane|microvillus membrane				ovary(1)	1						GAATGAGCTGGCCTCCGTGAA	0.602000													23	43					0	0	0.654019	0	0
ATG16L1	55054	broad.mit.edu	37	2	234173559	234173559	+	Silent	SNP	T	C	C			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr2:234173559T>C	uc002vty.2	+	5	668	c.411T>C	c.(409-411)ACT>ACC	p.T137T	ATG16L1_uc002vtx.1_Intron|ATG16L1_uc002vua.2_Silent_p.T137T|ATG16L1_uc002vub.2_Silent_p.T14T|ATG16L1_uc002vtz.2_Intron|ATG16L1_uc002vud.3_Silent_p.T53T	NM_030803	NP_110430	Q676U5	A16L1_HUMAN	APG16 autophagy 16-like isoform 1	137	Potential.				autophagic vacuole assembly|protein homooligomerization|protein transport	autophagic vacuole|pre-autophagosomal structure membrane	protein binding				0		Breast(86;0.0013)|Renal(207;0.00339)|all_hematologic(139;0.0116)|all_lung(227;0.0179)|Acute lymphoblastic leukemia(138;0.0327)|Lung NSC(271;0.0539)		Epithelial(121;1.53e-17)|BRCA - Breast invasive adenocarcinoma(100;0.000379)|LUSC - Lung squamous cell carcinoma(224;0.00619)|Lung(119;0.00732)|GBM - Glioblastoma multiforme(43;0.11)		GTTTGCAGACTATCTCTGACC	0.527000													36	66					0	0	0.788014	0	0
FGD5	152273	broad.mit.edu	37	3	14862235	14862235	+	Missense_Mutation	SNP	G	A	A	rs61751585		TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr3:14862235G>A	uc003bzc.2	+	1	1767	c.1657G>A	c.(1657-1659)GTG>ATG	p.V553M	FGD5_uc011avk.1_Missense_Mutation_p.V553M	NM_152536	NP_689749	Q6ZNL6	FGD5_HUMAN	FYVE, RhoGEF and PH domain containing 5	553					actin cytoskeleton organization|filopodium assembly|regulation of Cdc42 GTPase activity|regulation of cell shape	cytoskeleton|Golgi apparatus|lamellipodium|ruffle	metal ion binding|Rho guanyl-nucleotide exchange factor activity|small GTPase binding			ovary(3)|kidney(1)|pancreas(1)	5						GTCGTTCTCCGTGGAAGGCCG	0.557000													3	24					0	0	0.115264	0	0
DOCK4	9732	broad.mit.edu	37	7	111368503	111368503	+	Missense_Mutation	SNP	G	C	C			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr7:111368503G>C	uc003vfx.2	-	52	5997	c.5728C>G	c.(5728-5730)CTG>GTG	p.L1910V	DOCK4_uc011kml.1_Missense_Mutation_p.L791V|DOCK4_uc011kmm.1_Missense_Mutation_p.L779V|DOCK4_uc003vfw.2_Missense_Mutation_p.L1322V|DOCK4_uc003vfy.2_Missense_Mutation_p.L1955V|DOCK4_uc003vfv.2_Missense_Mutation_p.L223V	NM_014705	NP_055520	Q8N1I0	DOCK4_HUMAN	dedicator of cytokinesis 4	1910	Pro-rich.				cell chemotaxis	cytosol|endomembrane system|membrane|stereocilium	GTP binding|guanyl-nucleotide exchange factor activity|PDZ domain binding|Rac GTPase activator activity|Rac GTPase binding|receptor tyrosine kinase binding|SH3 domain binding			ovary(2)|haematopoietic_and_lymphoid_tissue(1)|central_nervous_system(1)	4		Acute lymphoblastic leukemia(1;0.0441)				GGGCGCCGCAGAGTCCGCTCG	0.726000													5	89					0	0	0.217242	0	0
GALNT11	63917	broad.mit.edu	37	7	151805279	151805279	+	Missense_Mutation	SNP	T	C	C			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr7:151805279T>C	uc010lqg.1	+	6	1099	c.869T>C	c.(868-870)GTC>GCC	p.V290A	GALNT11_uc011kvm.1_Missense_Mutation_p.V209A|GALNT11_uc003wku.2_Missense_Mutation_p.V290A|GALNT11_uc011kvn.1_RNA|GALNT11_uc003wkw.1_Missense_Mutation_p.V38A	NM_022087	NP_071370	Q8NCW6	GLT11_HUMAN	N-acetylgalactosaminyltransferase 11	290	Lumenal (Potential).					Golgi membrane|integral to membrane	polypeptide N-acetylgalactosaminyltransferase activity|sugar binding				0	all_neural(206;0.187)	all_hematologic(28;0.0592)|Prostate(32;0.214)	OV - Ovarian serous cystadenocarcinoma(82;0.00168)	UCEC - Uterine corpus endometrioid carcinoma (81;0.177)|BRCA - Breast invasive adenocarcinoma(188;0.0932)		TCCCCTGTCGTCCGCGGAGGG	0.602000													98	35					0	0	0.870114	0	0
MYOM2	9172	broad.mit.edu	37	8	2063780	2063780	+	Missense_Mutation	SNP	C	T	T			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr8:2063780C>T	uc003wpx.3	+	26	3347	c.3209C>T	c.(3208-3210)ACT>ATT	p.T1070I	MYOM2_uc011kwi.1_Missense_Mutation_p.T495I	NM_003970	NP_003961	P54296	MYOM2_HUMAN	myomesin 2	1070					muscle contraction	myosin filament	structural constituent of muscle			ovary(4)|central_nervous_system(1)|skin(1)	6		Ovarian(12;0.0572)|Colorectal(14;0.0844)|Hepatocellular(245;0.217)		BRCA - Breast invasive adenocarcinoma(11;1.85e-05)|Colorectal(4;0.0101)|READ - Rectum adenocarcinoma(4;0.148)|COAD - Colon adenocarcinoma(4;0.179)		GACAAAGCTACTGGCATTATT	0.383000													30	39					0	0	0.760397	0	0
KIAA1529	57653	broad.mit.edu	37	9	100117239	100117239	+	Missense_Mutation	SNP	A	G	G			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr9:100117239A>G	uc011lut.1	+	36	4535	c.3762A>G	c.(3760-3762)ATA>ATG	p.I1254M	KIAA1529_uc004axe.1_Missense_Mutation_p.I1086M|KIAA1529_uc004axg.1_Missense_Mutation_p.I1115M|KIAA1529_uc004axh.1_RNA|KIAA1529_uc011luw.1_Missense_Mutation_p.I271M	NM_020893	NP_065944			hypothetical protein LOC57653											ovary(4)|large_intestine(2)|skin(1)	7		Acute lymphoblastic leukemia(62;0.154)				TTATTTTCATAGAGAAAATCC	0.418000													44	53					0	0	0.859065	0	0
DNAJC25-GNG10	552891	broad.mit.edu	37	9	114429094	114429094	+	Splice_Site	SNP	G	A	A			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr9:114429094G>A	uc004bfn.2	+	2	359	c.337_splice	c.e2-1	p.V113_splice	GNG10_uc011lws.1_Splice_Site|GNG10_uc004bfp.2_Splice_Site_p.V28_splice	NM_004125	NP_004116	Q9H1X3	DJC25_HUMAN	DNAJC25-GNG10 protein						protein folding	integral to membrane	heat shock protein binding|unfolded protein binding				0						CTTTGTTTCAGGTCTCTCAGG	0.522000													12	23					0	0	0.435327	0	0
ZBTB33	10009	broad.mit.edu	37	X	119387346	119387346	+	Missense_Mutation	SNP	C	T	T			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chrX:119387346C>T	uc004esn.1	+	2	304	c.76C>T	c.(76-78)CGT>TGT	p.R26C	ZBTB33_uc010nqm.1_Missense_Mutation_p.R26C	NM_006777	NP_006768	Q86T24	KAISO_HUMAN	kaiso	26	Interaction with NCOR1.|Self-association (By similarity).				intracellular signal transduction|regulation of transcription, DNA-dependent|transcription, DNA-dependent|Wnt receptor signaling pathway	cytoplasm|nucleolus|plasma membrane	DNA binding|protein binding|zinc ion binding			ovary(1)|pancreas(1)|skin(1)	3						GAATGAGCAACGTGGCCATGG	0.448000													5	124					0	0	0.217242	0	0
ARHGAP21	57584	broad.mit.edu	37	10	24885703	24885704	+	Frame_Shift_Ins	INS	-	G	G			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr10:24885703_24885704insG	uc001isb.2	-	17	3929_3930	c.3442_3443insC	c.(3442-3444)CGAfs	p.R1148fs	ARHGAP21_uc010qdb.1_RNA|ARHGAP21_uc009xkl.1_Frame_Shift_Ins_p.R1148fs	NM_020824	NP_065875	Q5T5U3	RHG21_HUMAN	Rho GTPase activating protein 21	1147	Rho-GAP.				signal transduction	cell junction|cytoplasmic vesicle membrane|cytoskeleton|Golgi membrane	GTPase activator activity|protein binding			ovary(7)|pancreas(1)	8						GTCATCTAGTCGGACGCCGAAA	0.455													42	56	---	---	---	---					
Unknown	0	broad.mit.edu	37	15	84946555	84946556	+	RNA	INS	-	TT	TT	rs71453238		TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr15:84946555_84946556insTT	uc002bke.1	-	1		c.662_663insAA								Homo sapiens cDNA FLJ34196 fis, clone FCBBF3019437.																		CGAAGGGAGGAttttttttttt	0.515													4	3	---	---	---	---					
PVRL2	5819	broad.mit.edu	37	19	45349842	45349844	+	In_Frame_Del	DEL	GCT	-	-			TCGA-DW-7842-01A-11D-2136-08	TCGA-DW-7842-10A-01D-2136-08									Somatic	Phase_I	Capture				Illumina GAIIx	fe91ee01-61e4-4310-b1e9-387033d215a6	bbdb56a6-a63a-419c-91dc-54bd9502aa64	g.chr19:45349842_45349844delGCT	uc002ozw.1	+	1	450_452	c.60_62delGCT	c.(58-63)CCGCTG>CCG	p.L27del	PVRL2_uc002ozv.2_In_Frame_Del_p.L27del	NM_001042724	NP_001036189	Q92692	PVRL2_HUMAN	poliovirus receptor related 2 isoform delta	27					adherens junction organization|adhesion to symbiont|cell junction assembly|homophilic cell adhesion|positive regulation of immunoglobulin mediated immune response|positive regulation of mast cell activation|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|susceptibility to natural killer cell mediated cytotoxicity|susceptibility to T cell mediated cytotoxicity|viral envelope fusion with host membrane|virion attachment, binding of host cell surface coreceptor	cell surface|integral to membrane|zonula adherens	cell adhesion molecule binding|coreceptor activity|protein homodimerization activity				0	Lung NSC(12;0.00195)|all_lung(12;0.00522)	Ovarian(192;0.0728)|all_neural(266;0.112)		OV - Ovarian serous cystadenocarcinoma(262;0.0143)		tgctgtggccgctgctgctgctg	0.626													3	3	---	---	---	---					
