Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PRAMEF1	65121	broad.mit.edu	37	1	12853498	12853498	+	Missense_Mutation	SNP	T	G	G	rs149824309		TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr1:12853498T>G	uc001auj.1	+	2	225	c.122T>G	c.(121-123)ATG>AGG	p.M41R		NM_023013	NP_075389	O95521	PRAM1_HUMAN	PRAME family member 1	41											0	Ovarian(185;0.249)	Renal(390;0.000469)|Lung NSC(185;0.00143)|all_lung(284;0.00181)|Colorectal(325;0.00215)|Breast(348;0.0042)|Myeloproliferative disorder(586;0.0393)|Hepatocellular(190;0.0623)|Ovarian(437;0.0731)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00812)|Colorectal(212;4.88e-06)|Kidney(185;4.89e-05)|KIRC - Kidney renal clear cell carcinoma(229;0.000194)|COAD - Colon adenocarcinoma(227;0.000241)|BRCA - Breast invasive adenocarcinoma(304;0.000293)|STAD - Stomach adenocarcinoma(313;0.0072)|READ - Rectum adenocarcinoma(331;0.0649)		CCACTCTTCATGGAGGCCTTC	0.587000													103	36					0	0	0.014410	0	0
PKP1	5317	broad.mit.edu	37	1	201282317	201282317	+	Silent	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr1:201282317G>A	uc001gwd.2	+	3	581	c.330G>A	c.(328-330)CGG>CGA	p.R110R	PKP1_uc001gwe.2_Silent_p.R110R|PKP1_uc009wzm.2_5'UTR	NM_000299	NP_000290	Q13835	PKP1_HUMAN	plakophilin 1 isoform 1b	110					cell adhesion|cellular component disassembly involved in apoptosis|multicellular organismal development	desmosome|intermediate filament|nucleus	intermediate filament binding|signal transducer activity|structural constituent of epidermis			ovary(2)	2						CCCTCAAGCGGGAGCCTGACA	0.592000													6	4					0	0	0.001168	0	0
PLCE1	51196	broad.mit.edu	37	10	96084175	96084175	+	Missense_Mutation	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr10:96084175G>A	uc001kjk.2	+	31	7205	c.6571G>A	c.(6571-6573)GAA>AAA	p.E2191K	PLCE1_uc010qnx.1_Missense_Mutation_p.E2175K|PLCE1_uc001kjm.2_Missense_Mutation_p.E1883K|PLCE1_uc001kjp.2_Missense_Mutation_p.E549K	NM_016341	NP_057425	Q9P212	PLCE1_HUMAN	phospholipase C, epsilon 1 isoform 1	2191	Ras-associating 2.				activation of MAPK activity|activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|calcium-mediated signaling|cell proliferation|cytoskeleton organization|diacylglycerol biosynthetic process|elevation of cytosolic calcium ion concentration|epidermal growth factor receptor signaling pathway|glomerulus development|heart development|lipid catabolic process|Ras protein signal transduction|regulation of cell growth|regulation of G-protein coupled receptor protein signaling pathway|regulation of Ras protein signal transduction|regulation of smooth muscle contraction	cytosol|Golgi membrane|membrane fraction|plasma membrane	calcium ion binding|guanyl-nucleotide exchange factor activity|phosphatidylinositol phospholipase C activity|Ras GTPase binding|receptor signaling protein activity			ovary(2)|skin(1)	3		Colorectal(252;0.0458)				TGTGCTTTTGGAAGAGGTGGT	0.448000													124	141					0	0	0.014410	0	0
RNH1	6050	broad.mit.edu	37	11	498031	498031	+	Missense_Mutation	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr11:498031G>A	uc001lpk.1	-	7	2475	c.1067C>T	c.(1066-1068)GCG>GTG	p.A356V	RNH1_uc001lpl.1_Missense_Mutation_p.A356V|RNH1_uc001lpm.1_Missense_Mutation_p.A356V|RNH1_uc001lpn.1_Missense_Mutation_p.A356V|RNH1_uc001lpo.1_Missense_Mutation_p.A356V|RNH1_uc009ybw.1_RNA|RNH1_uc001lpp.1_Missense_Mutation_p.A356V|RNH1_uc001lpt.1_Missense_Mutation_p.A113V|RNH1_uc001lpq.1_Missense_Mutation_p.A356V|RNH1_uc001lpr.1_Missense_Mutation_p.A356V|RNH1_uc001lps.1_Missense_Mutation_p.A356V	NM_203389	NP_976323	P13489	RINI_HUMAN	ribonuclease/angiogenin inhibitor	356	LRR 12.				mRNA catabolic process|regulation of angiogenesis	angiogenin-PRI complex|cytoplasm	protein binding|ribonuclease inhibitor activity				0		all_cancers(49;3.02e-09)|all_epithelial(84;2.09e-06)|Breast(177;0.000162)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.0538)|all_lung(207;0.0713)		all cancers(45;1.26e-26)|Epithelial(43;1.34e-25)|OV - Ovarian serous cystadenocarcinoma(40;5.31e-20)|BRCA - Breast invasive adenocarcinoma(625;8.01e-05)|Lung(200;0.0378)|LUSC - Lung squamous cell carcinoma(625;0.0703)		CCGCACGCCCGCATCCTCCAG	0.612000													4	109					0	0	0.009096	0	0
LTBP3	4054	broad.mit.edu	37	11	65321228	65321228	+	Missense_Mutation	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr11:65321228G>A	uc001oej.2	-	3	1077	c.808C>T	c.(808-810)CCG>TCG	p.P270S	LTBP3_uc010roi.1_Missense_Mutation_p.P153S|LTBP3_uc001oei.2_Missense_Mutation_p.P270S|LTBP3_uc010roj.1_Intron|LTBP3_uc010rok.1_Missense_Mutation_p.P181S	NM_001130144	NP_001123616	Q9NS15	LTBP3_HUMAN	latent transforming growth factor beta binding	270						extracellular region	calcium ion binding|growth factor binding			central_nervous_system(2)|lung(1)	3						TGGGTGGGCGGCCGGGGGTGC	0.677000													3	15					0	0	0.009096	0	0
UNC93B1	81622	broad.mit.edu	37	11	67764189	67764189	+	Missense_Mutation	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr11:67764189C>T	uc001omw.1	-	9	1053	c.973G>A	c.(973-975)GGC>AGC	p.G325S		NM_030930	NP_112192	Q9H1C4	UN93B_HUMAN	unc-93 homolog B1	325					innate immune response|intracellular protein transport|response to virus|toll-like receptor 3 signaling pathway|toll-like receptor 7 signaling pathway|toll-like receptor 9 signaling pathway	early phagosome|endoplasmic reticulum membrane|endosome|integral to membrane|lysosome					0						AAGATGTTGCCCCAGCCCACG	0.622000													3	2					0	0	0.009096	0	0
BCL9L	283149	broad.mit.edu	37	11	118779318	118779318	+	Missense_Mutation	SNP	A	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr11:118779318A>G	uc001pug.2	-	2	1038	c.73T>C	c.(73-75)TCC>CCC	p.S25P	BCL9L_uc009zal.2_Missense_Mutation_p.S20P	NM_182557	NP_872363	Q86UU0	BCL9L_HUMAN	B-cell CLL/lymphoma 9-like	25					negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of epithelial to mesenchymal transition|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent		transcription coactivator activity			ovary(1)|pancreas(1)	2	all_hematologic(175;0.0839)	Medulloblastoma(222;0.0425)|all_hematologic(192;0.103)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;7.66e-05)		CCGCGGGGGGACAGCGGCGGG	0.592000													3	113					0	0	0.003080	0	0
DDX12	440081	broad.mit.edu	37	12	9583286	9583286	+	Silent	SNP	A	G	G	rs2429895	by1000genomes	TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr12:9583286A>G	uc010sgs.1	-	10	1335	c.1140T>C	c.(1138-1140)GCT>GCC	p.A380A		NM_004400	NP_004391			DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12												0						GGATGCCCGCAGCCTGCCGAG	0.672000													4	17					0	0	0.000602	0	0
NT5DC3	51559	broad.mit.edu	37	12	104179169	104179169	+	Missense_Mutation	SNP	A	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr12:104179169A>G	uc010swe.1	-	12	1314	c.1273T>C	c.(1273-1275)TAC>CAC	p.Y425H		NM_001031701	NP_001026871	Q86UY8	NT5D3_HUMAN	5'-nucleotidase domain containing 3	425							hydrolase activity|metal ion binding			ovary(2)|skin(1)	3						GTTTGAATGTATTGCTCCGTG	0.428000													45	47					0	0	0.013114	0	0
TCP11L2	255394	broad.mit.edu	37	12	106729466	106729466	+	Missense_Mutation	SNP	A	C	C			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr12:106729466A>C	uc001tln.2	+	7	996	c.822A>C	c.(820-822)GAA>GAC	p.E274D		NM_152772	NP_689985	Q8N4U5	T11L2_HUMAN	t-complex 11 (mouse) like 2	274										ovary(3)	3						TAAATGAAGAATTATTTTCTC	0.398000													33	36					0	0	0.010818	0	0
LOC284232	284232	broad.mit.edu	37	13	19415641	19415641	+	RNA	SNP	A	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr13:19415641A>T	uc010tcj.1	-	1		c.30469T>A				NR_027995				Homo sapiens ankyrin repeat domain 20 family, member A2 pseudogene (LOC284232), non-coding RNA.												0						aaaaaaaaaaaaacccaaaca	0.169000													4	40					0	0	0.000602	0	0
POLG	5428	broad.mit.edu	37	15	89864982	89864982	+	Silent	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr15:89864982G>A	uc002bns.3	-	16	2865	c.2583C>T	c.(2581-2583)ACC>ACT	p.T861T	POLG_uc002bnr.3_Silent_p.T861T	NM_002693	NP_002684	P54098	DPOG1_HUMAN	DNA-directed DNA polymerase gamma	861					base-excision repair, gap-filling|cell death|DNA-dependent DNA replication	mitochondrial nucleoid	DNA binding|DNA-directed DNA polymerase activity|protease binding			ovary(1)|lung(1)	2	Lung NSC(78;0.0472)|all_lung(78;0.089)		STAD - Stomach adenocarcinoma(125;0.165)			CATTGCTGGCGGTGAGCCATG	0.602000								DNA_polymerases_(catalytic_subunits)					49	65					0	0	0.014410	0	0
UBN1	29855	broad.mit.edu	37	16	4927066	4927066	+	Silent	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr16:4927066C>T	uc002cyb.2	+	16	3558	c.3219C>T	c.(3217-3219)ATC>ATT	p.I1073I	UBN1_uc010uxw.1_Silent_p.I1073I|UBN1_uc002cyc.2_Silent_p.I1073I	NM_001079514	NP_001072982	Q9NPG3	UBN1_HUMAN	ubinuclein 1	1073					chromatin modification|interspecies interaction between organisms|regulation of transcription from RNA polymerase II promoter	PML body|tight junction	DNA binding|sequence-specific DNA binding transcription factor activity			skin(2)	2						AGGATGCCATCGTCACAGGCC	0.572000													117	153					0	0	0.014410	0	0
MARVELD3	91862	broad.mit.edu	37	16	71668568	71668568	+	Silent	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr16:71668568C>T	uc002fat.2	+	3	1131	c.1068C>T	c.(1066-1068)TTC>TTT	p.F356F	MARVELD3_uc002fau.2_Intron|MARVELD3_uc010cge.2_Intron	NM_052858	NP_443090	Q96A59	MALD3_HUMAN	MARVEL domain containing 3 isoform 2	356	MARVEL.|Extracellular (Potential).					integral to membrane				skin(1)	1		Ovarian(137;0.125)				GCTGCAGTTTCCACGGAGCAG	0.542000													41	41					0	0	0.006999	0	0
OR1A1	8383	broad.mit.edu	37	17	3119076	3119076	+	Silent	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr17:3119076C>T	uc010vrc.1	+	1	162	c.162C>T	c.(160-162)CGC>CGT	p.R54R		NM_014565	NP_055380	Q9P1Q5	OR1A1_HUMAN	olfactory receptor, family 1, subfamily A,	54	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|skin(1)	2						CTGATGTTCGCCTTCACAACC	0.458000													7	362					0	0	0.006214	0	0
KRT34	3885	broad.mit.edu	37	17	39538275	39538275	+	Missense_Mutation	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr17:39538275C>T	uc002hwm.2	-	1	362	c.350G>A	c.(349-351)CGT>CAT	p.R117H		NM_021013	NP_066293	O76011	KRT34_HUMAN	keratin 34	117	Rod.|Coil 1A.				epidermis development	intermediate filament	protein binding|structural molecule activity			central_nervous_system(1)	1		Breast(137;0.000496)				CTCCAGCTGACGCACCTTCTC	0.597000													78	120					0	0	0.014410	0	0
DSG2	1829	broad.mit.edu	37	18	29102122	29102122	+	Silent	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr18:29102122C>T	uc002kwu.3	+	6	788	c.600C>T	c.(598-600)ATC>ATT	p.I200I		NM_001943	NP_001934	Q14126	DSG2_HUMAN	desmoglein 2 preproprotein	200	Extracellular (Potential).|Cadherin 2.				cellular component disassembly involved in apoptosis|homophilic cell adhesion	desmosome|integral to membrane	calcium ion binding			central_nervous_system(5)|ovary(2)|breast(1)|skin(1)	9			OV - Ovarian serous cystadenocarcinoma(10;0.0068)			CCTATAGAATCGTATCTCTGG	0.378000													17	41					0	0	0.004007	0	0
KCNG2	26251	broad.mit.edu	37	18	77624219	77624219	+	Silent	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr18:77624219G>A	uc010xfl.1	+	1	552	c.552G>A	c.(550-552)GTG>GTA	p.V184V		NM_012283	NP_036415	Q9UJ96	KCNG2_HUMAN	potassium voltage-gated channel, subfamily G,	184	Helical; Name=Segment S1; (Potential).				energy reserve metabolic process|regulation of heart contraction|regulation of insulin secretion	voltage-gated potassium channel complex	delayed rectifier potassium channel activity				0		Esophageal squamous(42;0.0157)|Melanoma(33;0.144)		OV - Ovarian serous cystadenocarcinoma(15;6.92e-07)|BRCA - Breast invasive adenocarcinoma(31;0.0244)		GCGTGTCCGTGTCCTTCGTGG	0.458000													14	33					0	0	0.003163	0	0
CD97	976	broad.mit.edu	37	19	14508025	14508025	+	Silent	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr19:14508025C>T	uc002myl.2	+	6	738	c.615C>T	c.(613-615)ACC>ACT	p.T205T	CD97_uc002mym.2_Intron|CD97_uc002myn.2_Intron	NM_078481	NP_510966	P48960	CD97_HUMAN	CD97 antigen isoform 1 precursor	205	Extracellular (Potential).|EGF-like 4; calcium-binding (Potential).				cell adhesion|cell-cell signaling|cellular component movement|immune response|inflammatory response|neuropeptide signaling pathway	extracellular space|integral to plasma membrane	calcium ion binding|G-protein coupled receptor activity|protein binding			ovary(3)|breast(1)	4						CAAACAATACCGTCTGTGAAG	0.582000													96	130					0	0	0.014410	0	0
RNF103	7844	broad.mit.edu	37	2	86831209	86831209	+	Silent	SNP	T	C	C			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr2:86831209T>C	uc002srn.2	-	4	2784	c.1815A>G	c.(1813-1815)GAA>GAG	p.E605E	VPS24_uc010ytl.1_Intron|RNF103_uc002srm.2_Silent_p.E466E|uc002sro.2_RNA	NM_005667	NP_005658	O00237	RN103_HUMAN	ring finger protein 103	605					central nervous system development|ER-associated protein catabolic process	endoplasmic reticulum membrane|integral to membrane	protein binding|ubiquitin-protein ligase activity|zinc ion binding			central_nervous_system(1)	1						ACCAATCAGGTTCCATATCTT	0.413000													92	151					0	0	0.014410	0	0
LRP1B	53353	broad.mit.edu	37	2	142567938	142567938	+	Missense_Mutation	SNP	A	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr2:142567938A>G	uc002tvj.1	-	2	1087	c.115T>C	c.(115-117)TGC>CGC	p.C39R	LRP1B_uc010fnl.1_Missense_Mutation_p.C76R	NM_018557	NP_061027	Q9NZR2	LRP1B_HUMAN	low density lipoprotein-related protein 1B	39	Extracellular (Potential).|LDL-receptor class A 1.				protein transport|receptor-mediated endocytosis	integral to membrane	calcium ion binding			lung(17)|skin(12)|ovary(12)|pancreas(3)|upper_aerodigestive_tract(2)|central_nervous_system(2)|liver(1)|kidney(1)	50		all_cancers(3;1.1e-60)|all_epithelial(3;1.94e-59)|all_lung(3;1.09e-24)|Lung NSC(3;5.65e-24)|Esophageal squamous(3;5.41e-13)|Renal(3;0.000147)|Breast(3;0.000527)|Hepatocellular(3;0.011)|all_neural(3;0.014)|Colorectal(150;0.101)		UCEC - Uterine corpus endometrioid carcinoma (2;0.00139)|Epithelial(1;1.25e-24)|all cancers(1;8.86e-24)|OV - Ovarian serous cystadenocarcinoma(1;2.45e-12)|LUSC - Lung squamous cell carcinoma(1;2.97e-10)|Lung(1;6.05e-09)|BRCA - Breast invasive adenocarcinoma(221;0.0103)		TGATCGTGGCAAAGAAATTCA	0.443000										TSP Lung(27;0.18)			22	16					0	0	0.012319	0	0
IDH1	3417	broad.mit.edu	37	2	209113112	209113112	+	Missense_Mutation	SNP	C	T	T	rs121913500		TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr2:209113112C>T	uc002vcs.2	-	4	641	c.395G>A	c.(394-396)CGT>CAT	p.R132H	IDH1_uc002vct.2_Missense_Mutation_p.R132H|IDH1_uc002vcu.2_Missense_Mutation_p.R132H	NM_005896	NP_005887	O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132		Substrate.	R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(2023)|p.R132C(344)|p.R132?(210)|p.R132G(117)|p.R132S(79)|p.R132L(58)|p.R132V(1)|p.G131_R132>VL(1)		central_nervous_system(2156)|haematopoietic_and_lymphoid_tissue(606)|bone(74)|thyroid(22)|large_intestine(4)|skin(2)|prostate(2)|autonomic_ganglia(1)|soft_tissue(1)	2868				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		ATAAGCATGACGACCTATGAT	0.393000			Mis		gliobastoma 								32	34					0	0	0.009535	0	0
FBXO36	130888	broad.mit.edu	37	2	230861511	230861511	+	Missense_Mutation	SNP	A	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr2:230861511A>G	uc002vqa.2	+	3	273	c.250A>G	c.(250-252)ATC>GTC	p.I84V	FBXO36_uc002vqb.2_Missense_Mutation_p.I53V|FBXO36_uc010fxi.1_Missense_Mutation_p.I84V|FBXO36_uc002vqc.2_RNA	NM_174899	NP_777559	Q8NEA4	FBX36_HUMAN	F-box protein 36	84										ovary(1)	1		Renal(207;0.0112)|all_lung(227;0.0179)|Lung NSC(271;0.0804)|all_hematologic(139;0.103)|Acute lymphoblastic leukemia(138;0.167)		Epithelial(121;7.56e-14)|all cancers(144;7.74e-11)|Lung(119;0.00488)|LUSC - Lung squamous cell carcinoma(224;0.008)		AGACTATGTCATCAATTTGTG	0.348000													50	69					0	0	0.014410	0	0
FRG1B	284802	broad.mit.edu	37	20	29628263	29628263	+	Missense_Mutation	SNP	A	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr20:29628263A>G	uc010ztl.1	+	3	207	c.175A>G	c.(175-177)ATT>GTT	p.I59V	FRG1B_uc002wvm.1_RNA|FRG1B_uc010ztj.1_RNA|FRG1B_uc010gdr.1_RNA|FRG1B_uc010ztk.1_Missense_Mutation_p.I11V					Homo sapiens cDNA FLJ32537 fis, clone SMINT2000400, highly similar to Homo sapiens FRG1 mRNA.												0						TAGCTGCTTTATTAGATGCAA	0.363000													7	61					0	0	0.001855	0	0
NCOA6	23054	broad.mit.edu	37	20	33345744	33345744	+	Silent	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr20:33345744C>T	uc002xav.2	-	8	3378	c.807G>A	c.(805-807)CAG>CAA	p.Q269Q	NCOA6_uc002xaw.2_Silent_p.Q269Q|NCOA6_uc010gew.1_Silent_p.Q226Q	NM_014071	NP_054790	Q14686	NCOA6_HUMAN	nuclear receptor coactivator 6	269	TBP/GTF2A-binding region.|NCOA1-binding region.|Gln-rich.|CREBBP-binding region.				brain development|cellular lipid metabolic process|DNA recombination|DNA repair|DNA replication|estrogen receptor signaling pathway|glucocorticoid receptor signaling pathway|heart development|myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|response to hormone stimulus|transcription initiation from RNA polymerase II promoter	transcription factor complex	chromatin binding|enzyme binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|retinoid X receptor binding|thyroid hormone receptor binding			ovary(3)|breast(3)|central_nervous_system(1)	7						gctgctgctgctgttgttgtt	0.313000													4	52					0	0	0.009096	0	0
ARFGEF2	10564	broad.mit.edu	37	20	47626800	47626800	+	Missense_Mutation	SNP	T	C	C			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr20:47626800T>C	uc002xtx.3	+	27	3768	c.3616T>C	c.(3616-3618)TGC>CGC	p.C1206R	ARFGEF2_uc010zyf.1_Missense_Mutation_p.C499R	NM_006420	NP_006411	Q9Y6D5	BIG2_HUMAN	ADP-ribosylation factor guanine	1206					exocytosis|intracellular signal transduction|regulation of ARF protein signal transduction	cytosol|Golgi membrane	ARF guanyl-nucleotide exchange factor activity			breast(3)|upper_aerodigestive_tract(1)	4			BRCA - Breast invasive adenocarcinoma(12;0.00148)|Colorectal(8;0.198)			GGCGATCCGCTGCATTGCCCA	0.537000													27	83					0	0	0.003954	0	0
Unknown	0	broad.mit.edu	37	22	18846113	18846113	+	RNA	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr22:18846113C>T	uc002zoe.2	+	5		c.2475C>T			uc002zof.2_5'Flank					Homo sapiens cDNA FLJ76361 complete cds.																		ATCTCCTCCACGCACTGGCGC	0.612000													4	32					0	0	0.009096	0	0
LOC96610	96610	broad.mit.edu	37	22	22664606	22664606	+	RNA	SNP	A	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr22:22664606A>G	uc011aim.1	+	31		c.2121A>G			LOC96610_uc011aiq.1_RNA					Parts of antibodies, mostly variable regions.												0						GTCTTCATGCAAACTTGGTAT	0.398000													3	28					0	0	0.004672	0	0
PCDHGA7	56108	broad.mit.edu	37	5	140764645	140764645	+	Missense_Mutation	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr5:140764645G>A	uc003lka.1	+	1	2179	c.2179G>A	c.(2179-2181)GCT>ACT	p.A727T	PCDHGA1_uc003lji.1_Intron|PCDHGA2_uc003ljk.1_Intron|PCDHGA3_uc003ljm.1_Intron|PCDHGA3_uc010jfx.1_Intron|PCDHGB1_uc003ljo.1_Intron|PCDHGA4_uc003ljq.1_Intron|PCDHGB2_uc003ljs.1_Intron|PCDHGA5_uc003lju.1_Intron|PCDHGB3_uc003ljw.1_Intron|PCDHGA6_uc003ljy.1_Intron|PCDHGB4_uc003lkc.1_5'Flank|PCDHGA7_uc003ljz.1_Missense_Mutation_p.A727T|PCDHGB4_uc011dav.1_5'Flank	NM_018920	NP_061743	Q9Y5G6	PCDG7_HUMAN	protocadherin gamma subfamily A, 7 isoform 1	727	Cytoplasmic (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding				0			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			CCTGCTGCAGGCTTCAGAAGG	0.637000													50	42					0	0	0.014410	0	0
CLIP2	7461	broad.mit.edu	37	7	73731911	73731911	+	Missense_Mutation	SNP	G	A	A	rs151111065	byFrequency	TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr7:73731911G>A	uc003uam.2	+	2	362	c.35G>A	c.(34-36)CGT>CAT	p.R12H	CLIP2_uc003uan.2_Missense_Mutation_p.R12H	NM_003388	NP_003379	Q9UDT6	CLIP2_HUMAN	CAP-GLY domain containing linker protein 2	12						microtubule associated complex				skin(3)	3						CCCCCCGGCCGTGGGGGGAAG	0.662000													35	102					0	0	0.003755	0	0
SRRM3	222183	broad.mit.edu	37	7	75896665	75896665	+	Missense_Mutation	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr7:75896665G>A	uc010ldi.2	+	11	1129	c.920G>A	c.(919-921)GGA>GAA	p.G307E	SRRM3_uc011kgi.1_5'UTR	NM_001110199	NP_001103669			serine/arginine repetitive matrix 3												0						GGCGGCAGCGGATGGGGGTCG	0.751000													3	5					0	0	0.009096	0	0
DLX5	1749	broad.mit.edu	37	7	96650149	96650149	+	Missense_Mutation	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr7:96650149C>T	uc003uon.2	-	3	977	c.769G>A	c.(769-771)GCA>ACA	p.A257T		NM_005221	NP_005212	P56178	DLX5_HUMAN	distal-less homeobox 5	257					cell proliferation|endochondral ossification|osteoblast differentiation|positive regulation of transcription, DNA-dependent	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding			ovary(1)	1	all_cancers(62;9.56e-09)|all_epithelial(64;7.38e-09)|Esophageal squamous(72;0.0125)|all_lung(186;0.0855)|Lung NSC(181;0.0858)					TACCAGGATGCAGAGTTCTCC	0.652000													33	32					0	0	0.003271	0	0
MKLN1	4289	broad.mit.edu	37	7	131128404	131128404	+	Silent	SNP	T	C	C			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr7:131128404T>C	uc011kpm.1	+	11	1402	c.1338T>C	c.(1336-1338)TGT>TGC	p.C446C	MKLN1_uc011kpl.1_Silent_p.C423C|MKLN1_uc010lmh.2_Silent_p.C446C|MKLN1_uc003vqs.2_Silent_p.C239C	NM_013255	NP_037387	Q9UL63	MKLN1_HUMAN	muskelin 1, intracellular mediator containing	446	Kelch 3.				signal transduction	cytoplasm	protein binding			breast(1)	1	Melanoma(18;0.162)					AGGACTCCTGTAATGCTGGGC	0.448000													3	93					0	0	0.000602	0	0
Unknown	0	broad.mit.edu	37	9	68414259	68414259	+	RNA	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr9:68414259C>T	uc004aex.2	+	1		c.814C>T								Homo sapiens mRNA; cDNA DKFZp564N0763 (from clone DKFZp564N0763).																		ccacagtggcctcaaagaact	0.254000													2	4					0	0	0.004672	0	0
FAM75C1	441452	broad.mit.edu	37	9	90536583	90536583	+	Silent	SNP	C	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr9:90536583C>T	uc010mqi.2	+	4	1790	c.1761C>T	c.(1759-1761)GGC>GGT	p.G587G	FAM75C1_uc004apq.3_Silent_p.G570G	NM_001145124	NP_001138596			family with sequence similarity 75, member C1												0						CCCACATGGGCAGAAAGTTGG	0.512000													119	116					0	0	0.014410	0	0
KIAA0368	23392	broad.mit.edu	37	9	114170943	114170943	+	Nonsense_Mutation	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr9:114170943G>A	uc004bfe.1	-	25	3094	c.3094C>T	c.(3094-3096)CGA>TGA	p.R1032*		NM_001080398	NP_001073867			KIAA0368 protein												0						TGGATTGCTCGTTCTTTCATC	0.398000													11	5					0	0	0.010729	0	0
MORN5	254956	broad.mit.edu	37	9	124932034	124932034	+	Silent	SNP	A	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr9:124932034A>G	uc004blw.2	+	3	368	c.306A>G	c.(304-306)GCA>GCG	p.A102A	MORN5_uc011lyn.1_Silent_p.A102A|MORN5_uc011lyo.1_Intron	NM_198469	NP_940871	Q5VZ52	MORN5_HUMAN	MORN repeat containing 5	102											0						TGAAGCCTGCAGGTACCCAGG	0.478000													3	116					0	0	0.004672	0	0
NOTCH1	4851	broad.mit.edu	37	9	139413126	139413126	+	Missense_Mutation	SNP	C	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr9:139413126C>G	uc004chz.2	-	6	1016	c.1016G>C	c.(1015-1017)TGT>TCT	p.C339S		NM_017617	NP_060087	P46531	NOTC1_HUMAN	notch1 preproprotein	339	Extracellular (Potential).|EGF-like 9; calcium-binding (Potential).				aortic valve morphogenesis|immune response|negative regulation of BMP signaling pathway|negative regulation of cell-substrate adhesion|negative regulation of myoblast differentiation|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-dependent|Notch receptor processing	cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to membrane|nucleoplasm|plasma membrane	calcium ion binding|protein binding|receptor activity			haematopoietic_and_lymphoid_tissue(791)|upper_aerodigestive_tract(29)|lung(13)|central_nervous_system(10)|breast(9)|large_intestine(1)|skin(1)|oesophagus(1)|pancreas(1)	856	all_cancers(76;0.223)	Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;5.34e-06)|Epithelial(140;7.77e-06)		GGCGCTGGCACAGTCATCAAT	0.637000			T|Mis|O	TRB@	T-ALL					HNSCC(8;0.001)			3	75					0	0	0.004672	0	0
SSX6	280657	broad.mit.edu	37	X	47969964	47969964	+	Missense_Mutation	SNP	A	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chrX:47969964A>G	uc004dix.1	+	3	289	c.167A>G	c.(166-168)GAG>GGG	p.E56G	SSX6_uc011mlv.1_Missense_Mutation_p.E56G	NM_173357	NP_775493			SubName: Full=Putative uncharacterized protein SSX1;												0						AGAAAGTATGAGGCCATGACT	0.428000													3	94					0	0	0.004672	0	0
VSIG4	11326	broad.mit.edu	37	X	65247365	65247365	+	Missense_Mutation	SNP	G	A	A			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chrX:65247365G>A	uc004dwh.2	-	5	888	c.761C>T	c.(760-762)ACA>ATA	p.T254I	VSIG4_uc004dwi.2_Missense_Mutation_p.T160I|VSIG4_uc010nkq.1_Missense_Mutation_p.T254I|VSIG4_uc004dwj.2_Missense_Mutation_p.T254I|VSIG4_uc011moy.1_Missense_Mutation_p.T160I|VSIG4_uc004dwk.2_Missense_Mutation_p.T254I|VSIG4_uc004dwl.2_Missense_Mutation_p.T150I	NM_007268	NP_009199	Q9Y279	VSIG4_HUMAN	V-set and immunoglobulin domain containing 4	254	Extracellular (Potential).				complement activation, alternative pathway	integral to membrane	protein binding				0						CACTGTAGATGTTGCTATGAA	0.468000													8	14					0	0	0.003080	0	0
NCAM1	4684	broad.mit.edu	37	11	113102455	113102456	+	In_Frame_Ins	INS	-	CCCTCT	CCCTCT			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr11:113102455_113102456insCCCTCT	uc009yyq.1	+	11	1596_1597	c.902_903insCCCTCT	c.(901-903)TAC>TACCCTCTC	p.301_302insPL		NM_001076682	NP_001070150	P13591	NCAM1_HUMAN	neural cell adhesion molecule 1 isoform 3	393_394	Ig-like C2-type 4.|Extracellular (Potential).				axon guidance|interferon-gamma-mediated signaling pathway	anchored to membrane|extracellular region|Golgi membrane|integral to membrane				ovary(1)	1		all_cancers(61;5.82e-19)|all_epithelial(67;6.87e-12)|Melanoma(852;1.99e-05)|all_hematologic(158;3.66e-05)|Acute lymphoblastic leukemia(157;0.00119)|Breast(348;0.0109)|all_neural(223;0.0299)|Medulloblastoma(222;0.0458)|Renal(330;0.198)|Prostate(24;0.207)		BRCA - Breast invasive adenocarcinoma(274;1.78e-05)|Epithelial(105;0.000114)|all cancers(92;0.000467)|OV - Ovarian serous cystadenocarcinoma(223;0.212)		GCCGGAGAGTACATCTGCACCG	0.594													9	114	---	---	---	---					
TCF12	6938	broad.mit.edu	37	15	57523456	57523457	+	Splice_Site	INS	-	T	T			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr15:57523456_57523457insT	uc002aec.2	+	9	969	c.685_splice	c.e9+1	p.D229_splice	TCF12_uc010ugm.1_Splice_Site_p.D281_splice|TCF12_uc010ugn.1_Splice_Site_p.D225_splice|TCF12_uc002aea.2_Splice_Site_p.D229_splice|TCF12_uc010bfs.2_Intron|TCF12_uc002aeb.2_Splice_Site_p.D229_splice|TCF12_uc002aed.2_Splice_Site_p.D229_splice|TCF12_uc002aee.2_Splice_Site_p.D59_splice|TCF12_uc010bft.2_Splice_Site_p.D59_splice|TCF12_uc010ugo.1_Splice_Site_p.K39_splice	NM_207038	NP_996921	Q99081	HTF4_HUMAN	transcription factor 12 isoform b						immune response|muscle organ development|regulation of transcription from RNA polymerase II promoter	nucleus	DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			central_nervous_system(5)|ovary(2)|lung(1)	8		Colorectal(260;0.0907)		all cancers(107;0.000313)|GBM - Glioblastoma multiforme(80;0.00878)|STAD - Stomach adenocarcinoma(283;0.239)		TTTATGCAAGGTAAGTACTACC	0.386			T	TEC	extraskeletal myxoid chondrosarcoma								43	59	---	---	---	---					
CIC	23152	broad.mit.edu	37	19	42795074	42795075	+	Frame_Shift_Ins	INS	-	G	G			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr19:42795074_42795075insG	uc002otf.1	+	10	2194_2195	c.2154_2155insG	c.(2152-2157)CCTGGGfs	p.P718fs		NM_015125	NP_055940	Q96RK0	CIC_HUMAN	capicua homolog	718_719	Pro-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|protein binding			ovary(4)|breast(4)|lung(1)|central_nervous_system(1)|skin(1)	11		Prostate(69;0.00682)				CTCGGGTGCCTGGGGGCTCCCC	0.644			T	DUX4	soft tissue sarcoma								12	8	---	---	---	---					
NKD2	85409	broad.mit.edu	37	5	1038447	1038449	+	In_Frame_Del	DEL	CAC	-	-	rs3840989		TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr5:1038447_1038449delCAC	uc003jbt.1	+	10	1320_1322	c.1315_1317delCAC	c.(1315-1317)CACdel	p.H447del	NKD2_uc010itf.1_3'UTR	NM_033120	NP_149111	Q969F2	NKD2_HUMAN	naked cuticle homolog 2	447	His-rich.				exocytosis|Wnt receptor signaling pathway	cytoplasmic membrane-bounded vesicle|plasma membrane	calcium ion binding|ubiquitin protein ligase binding				0	Lung NSC(6;2.47e-13)|all_lung(6;1.67e-12)|all_epithelial(6;3.28e-09)		Epithelial(17;0.00093)|OV - Ovarian serous cystadenocarcinoma(19;0.00239)|all cancers(22;0.00417)|Lung(60;0.165)			ccaccacgagcaccaccaccacc	0.522													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	9	68413567	68413567	+	RNA	DEL	G	-	-			TCGA-CS-6668-01A-11D-1893-08	TCGA-CS-6668-10A-01D-1893-08									Somatic	Phase_I	Capture				Illumina GAIIx	d414e076-dcb6-4edf-adef-0abdc57354ea	7154a36b-c503-43f5-b291-89bd5ce2875f	g.chr9:68413567delG	uc004aex.2	+	1		c.122delG								Homo sapiens mRNA; cDNA DKFZp564N0763 (from clone DKFZp564N0763).																		CTCCCCCAGTGGCGCCGGATC	0.552													3	6	---	---	---	---					
