Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KIAA0562	9731	broad.mit.edu	37	1	3740070	3740070	+	Silent	SNP	G	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr1:3740070G>A	uc001aky.2	-	19	2780	c.2421C>T	c.(2419-2421)GAC>GAT	p.D807D	KIAA0562_uc010nzm.1_RNA	NM_014704	NP_055519	O60308	CE104_HUMAN	glycine-, glutamate-,	807						centriole	binding				0	all_cancers(77;0.0395)|Ovarian(185;0.0634)|all_lung(157;0.222)|Lung NSC(156;0.227)	all_epithelial(116;3.96e-21)|all_lung(118;2.74e-08)|Lung NSC(185;6.4e-06)|Breast(487;0.00066)|Renal(390;0.00121)|Hepatocellular(190;0.00335)|Myeloproliferative disorder(586;0.0255)|Ovarian(437;0.031)|Lung SC(97;0.0548)|Medulloblastoma(700;0.212)		Epithelial(90;6.85e-39)|OV - Ovarian serous cystadenocarcinoma(86;1.59e-22)|GBM - Glioblastoma multiforme(42;3.16e-16)|Colorectal(212;2.01e-05)|COAD - Colon adenocarcinoma(227;7.99e-05)|BRCA - Breast invasive adenocarcinoma(365;0.000389)|Kidney(185;0.000513)|STAD - Stomach adenocarcinoma(132;0.00709)|KIRC - Kidney renal clear cell carcinoma(229;0.00714)|Lung(427;0.137)		TTCCAAACCCGTCTTTTTTGT	0.493000													32	57					0	0	0.009535	0	0
IL22RA1	58985	broad.mit.edu	37	1	24447958	24447958	+	Silent	SNP	G	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr1:24447958G>A	uc001biq.1	-	7	1101	c.1062C>T	c.(1060-1062)AAC>AAT	p.N354N	IL22RA1_uc010oeg.1_Silent_p.N286N|IL22RA1_uc009vrb.1_Silent_p.N218N|IL22RA1_uc010oeh.1_Silent_p.N354N	NM_021258	NP_067081	Q8N6P7	I22R1_HUMAN	interleukin 22 receptor, alpha 1 precursor	354	Cytoplasmic (Potential).					integral to membrane	interferon receptor activity			skin(1)	1		Colorectal(325;3.46e-05)|Renal(390;0.0007)|Lung NSC(340;0.000992)|all_lung(284;0.00138)|Ovarian(437;0.00348)|Breast(348;0.0126)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|OV - Ovarian serous cystadenocarcinoma(117;3.84e-24)|Colorectal(126;6.43e-08)|COAD - Colon adenocarcinoma(152;3.51e-06)|GBM - Glioblastoma multiforme(114;5.06e-05)|BRCA - Breast invasive adenocarcinoma(304;0.00104)|KIRC - Kidney renal clear cell carcinoma(1967;0.00371)|STAD - Stomach adenocarcinoma(196;0.00911)|READ - Rectum adenocarcinoma(331;0.0655)|Lung(427;0.148)		CAGGGGCAGCGTTTGGGGCAT	0.607000													47	66					0	0	0.014410	0	0
PCSK9	255738	broad.mit.edu	37	1	55523126	55523126	+	Silent	SNP	C	T	T	rs139683719		TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr1:55523126C>T	uc001cyf.1	+	7	1410	c.1119C>T	c.(1117-1119)AGC>AGT	p.S373S	PCSK9_uc010oom.1_RNA	NM_174936	NP_777596	Q8NBP7	PCSK9_HUMAN	proprotein convertase subtilisin/kexin type 9	373	Peptidase S8.				cellular response to insulin stimulus|cellular response to starvation|cholesterol homeostasis|cholesterol metabolic process|kidney development|liver development|low-density lipoprotein particle receptor catabolic process|lysosomal transport|negative regulation of catalytic activity|negative regulation of low-density lipoprotein particle clearance|negative regulation of receptor recycling|neuron differentiation|positive regulation of neuron apoptosis|positive regulation of receptor internalization|protein autoprocessing|regulation of receptor activity	extracellular space|late endosome|lysosome|perinuclear region of cytoplasm	apolipoprotein receptor binding|identical protein binding|low-density lipoprotein particle receptor binding|serine-type endopeptidase activity|very-low-density lipoprotein particle receptor binding			ovary(2)|central_nervous_system(1)|skin(1)	4						GTGCCTCCAGCGACTGCAGCA	0.617000													7	25					0	0	0.003080	0	0
AMPD2	271	broad.mit.edu	37	1	110170831	110170831	+	Missense_Mutation	SNP	C	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr1:110170831C>T	uc009wfh.1	+	11	1911	c.1369C>T	c.(1369-1371)CGG>TGG	p.R457W	AMPD2_uc009wfg.1_RNA|AMPD2_uc001dyb.1_Missense_Mutation_p.R376W|AMPD2_uc001dyc.1_Missense_Mutation_p.R457W|AMPD2_uc010ovr.1_Missense_Mutation_p.R382W|AMPD2_uc010ovs.1_Missense_Mutation_p.R339W|AMPD2_uc001dyd.1_Missense_Mutation_p.R338W|AMPD2_uc001dye.1_5'Flank	NM_004037	NP_004028	Q01433	AMPD2_HUMAN	adenosine monophosphate deaminase 2 (isoform L)	457					purine base metabolic process|purine ribonucleoside monophosphate biosynthetic process|purine-containing compound salvage	cytosol	AMP deaminase activity|metal ion binding			ovary(2)|breast(1)	3		all_epithelial(167;2.5e-05)|all_lung(203;0.000135)|Lung NSC(277;0.000269)|Breast(1374;0.244)		Lung(183;0.0425)|all cancers(265;0.0884)|Colorectal(144;0.109)|Epithelial(280;0.111)|LUSC - Lung squamous cell carcinoma(189;0.228)		ACAGACGCTGCGGGAGGTCTT	0.602000													12	19					0	0	0.001855	0	0
CR2	1380	broad.mit.edu	37	1	207648381	207648381	+	Missense_Mutation	SNP	C	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr1:207648381C>T	uc001hfw.2	+	13	2453	c.2359C>T	c.(2359-2361)CGC>TGC	p.R787C	CR2_uc001hfv.2_Missense_Mutation_p.R846C|CR2_uc009xch.2_Missense_Mutation_p.R787C	NM_001877	NP_001868	P20023	CR2_HUMAN	complement component (3d/Epstein Barr virus)	787	Sushi 13.|Extracellular (Potential).			PPVTR -> L (in Ref. 3; AAA35784).	complement activation, classical pathway|innate immune response	integral to membrane|plasma membrane	complement receptor activity|protein homodimerization activity			upper_aerodigestive_tract(3)|skin(3)|urinary_tract(1)|ovary(1)	8						TCCTGTGACTCGCTGCCCTAA	0.463000													28	78					0	0	0.006320	0	0
ATRNL1	26033	broad.mit.edu	37	10	117061534	117061534	+	Nonsense_Mutation	SNP	G	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr10:117061534G>A	uc001lcg.2	+	17	3185	c.2799G>A	c.(2797-2799)TGG>TGA	p.W933*	ATRNL1_uc010qsm.1_Nonsense_Mutation_p.W108*|ATRNL1_uc010qsn.1_RNA	NM_207303	NP_997186	Q5VV63	ATRN1_HUMAN	attractin-like 1 precursor	933	PSI 4.|Extracellular (Potential).					integral to membrane	sugar binding			ovary(5)|lung(1)|central_nervous_system(1)	7		all_lung(145;0.0686)|Breast(234;0.0969)|Lung NSC(174;0.17)|Colorectal(252;0.234)		Epithelial(162;0.00031)|all cancers(201;0.000753)|LUSC - Lung squamous cell carcinoma(1;0.0515)|Lung(30;0.0827)		GTCTAGAGTGGCAAACTGCCA	0.388000													4	120					0	0	0.009096	0	0
OR5AN1	390195	broad.mit.edu	37	11	59132638	59132638	+	Missense_Mutation	SNP	C	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr11:59132638C>A	uc010rks.1	+	1	707	c.707C>A	c.(706-708)TCC>TAC	p.S236Y		NM_001004729	NP_001004729	Q8NGI8	O5AN1_HUMAN	olfactory receptor, family 5, subfamily AN,	236	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)	1						AAAGGCAGGTCCAAGGCATTC	0.423000													9	187					0.000673444	0.000750409	0.008291	1	0
LOC642846	642846	broad.mit.edu	37	12	9458891	9458891	+	RNA	SNP	A	G	G	rs140731402	by1000genomes	TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr12:9458891A>G	uc010sgp.1	+	17		c.1928A>G			LOC642846_uc001qvp.2_RNA	NR_024374				Homo sapiens cDNA FLJ60280 complete cds, highly similar to Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-).												0						CTTCCCCACTAATGCACATCG	0.612000													4	18					0	0	0.000602	0	0
OVCH1	341350	broad.mit.edu	37	12	29618094	29618094	+	Missense_Mutation	SNP	C	G	G			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr12:29618094C>G	uc001rix.1	-	17	1915	c.1915G>C	c.(1915-1917)GAA>CAA	p.E639Q		NM_183378	NP_899234	Q7RTY7	OVCH1_HUMAN	ovochymase 1 precursor	639	Peptidase S1 2.				proteolysis	extracellular region	metal ion binding|serine-type endopeptidase activity			ovary(3)|central_nervous_system(3)|pancreas(3)|large_intestine(1)	10	Lung NSC(12;1.84e-09)|Acute lymphoblastic leukemia(23;0.00885)|all_hematologic(23;0.0155)					TCTGTTGATTCCTTCAGGTTT	0.378000													2	5					0	0	0.004672	0	0
OAS2	4939	broad.mit.edu	37	12	113447044	113447044	+	Missense_Mutation	SNP	C	T	T	rs147522268	byFrequency	TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr12:113447044C>T	uc001tuj.2	+	10	2188	c.2048C>T	c.(2047-2049)CCG>CTG	p.P683L	OAS2_uc001tui.1_Missense_Mutation_p.P683L	NM_016817	NP_058197	P29728	OAS2_HUMAN	2'-5'-oligoadenylate synthetase 2 isoform 1	683	OAS domain 2.				interferon-gamma-mediated signaling pathway|nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|type I interferon-mediated signaling pathway	endoplasmic reticulum|membrane|microsome|mitochondrion|nucleus	ATP binding|nucleotidyltransferase activity|RNA binding			ovary(1)	1						TGGAAAGTGCCGGTAAAAGTC	0.458000													11	255					0	0	0.013537	0	0
TRIP4	9325	broad.mit.edu	37	15	64716294	64716294	+	Nonsense_Mutation	SNP	A	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr15:64716294A>T	uc002anm.2	+	10	1466	c.1423A>T	c.(1423-1425)AAA>TAA	p.K475*		NM_016213	NP_057297	Q15650	TRIP4_HUMAN	thyroid hormone receptor interactor 4	475					positive regulation of transcription, DNA-dependent|transcription from RNA polymerase II promoter	cytoplasm|nucleus	ligand-dependent nuclear receptor binding|transcription coactivator activity|zinc ion binding			ovary(1)|kidney(1)|skin(1)	3						CACAGCTAAAAAACCCTCCCC	0.448000													21	43					0	0	0.008871	0	0
WASH3P	374666	broad.mit.edu	37	15	102515335	102515335	+	Missense_Mutation	SNP	C	G	G			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr15:102515335C>G	uc002cdi.2	+	9	1979	c.559C>G	c.(559-561)CTG>GTG	p.L187V	WASH3P_uc002cdl.2_Missense_Mutation_p.L187V|WASH3P_uc002cdk.2_RNA|WASH3P_uc002cdp.2_Missense_Mutation_p.L187V|WASH3P_uc010bpo.2_RNA|WASH3P_uc002cdq.2_RNA|WASH3P_uc002cdr.2_RNA	NR_003659				RecName: Full=WAS protein family homolog 2; AltName: Full=Protein FAM39B; AltName: Full=CXYorf1-like protein on chromosome 2;												0						GGAGCGAAAGCTGGAGAAGAA	0.652000													5	13					0	0	0.003080	0	0
TP53	7157	broad.mit.edu	37	17	7578394	7578394	+	Missense_Mutation	SNP	T	C	C			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr17:7578394T>C	uc002gim.2	-	5	730	c.536A>G	c.(535-537)CAT>CGT	p.H179R	TP53_uc002gig.1_Missense_Mutation_p.H179R|TP53_uc002gih.2_Missense_Mutation_p.H179R|TP53_uc010cne.1_5'Flank|TP53_uc010cnf.1_Missense_Mutation_p.H47R|TP53_uc010cng.1_Missense_Mutation_p.H47R|TP53_uc002gii.1_Missense_Mutation_p.H47R|TP53_uc010cnh.1_Missense_Mutation_p.H179R|TP53_uc010cni.1_Missense_Mutation_p.H179R|TP53_uc002gij.2_Missense_Mutation_p.H179R|TP53_uc010cnj.1_RNA|TP53_uc002gin.2_Missense_Mutation_p.H86R|TP53_uc002gio.2_Missense_Mutation_p.H47R|TP53_uc010vug.1_Missense_Mutation_p.H140R	NM_001126112	NP_001119584	P04637	P53_HUMAN	tumor protein p53 isoform a	179	Required for interaction with FBXO42.||Interaction with HIPK1 (By similarity).|Interaction with AXIN1 (By similarity).	Zinc.	H -> Q (in sporadic cancers; somatic mutation).|H -> N (in sporadic cancers; somatic mutation).|H -> R (in sporadic cancers; somatic mutation).|HH -> QS (in a sporadic cancer; somatic mutation).|H -> L (in sporadic cancers; somatic mutation).|H -> D (in sporadic cancers; somatic mutation).|H -> P (in sporadic cancers; somatic mutation).|H -> Y (in LFS; germline mutation and in sporadic cancers; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.H179R(99)|p.H179Y(74)|p.H179L(31)|p.H179Q(17)|p.H179N(13)|p.H179D(10)|p.P177_C182delPHHERC(8)|p.0?(7)|p.C176_R181delCPHHER(3)|p.R174fs*24(3)|p.H179P(3)|p.R175_E180delRCPHHE(3)|p.H179fs*68(2)|p.H179H(2)|p.P177fs*3(2)|p.V173fs*59(2)|p.R174fs*1(2)|p.K164_P219del(1)|p.C176fs*65(1)|p.P177_H179delPHH(1)|p.V173fs*23(1)|p.V172_E180delVVRRCPHHE(1)|p.R174_H179delRRCPHH(1)|p.H179del(1)|p.E171_H179delEVVRRCPHH(1)|p.R81fs*24(1)|p.R174_E180>K(1)|p.H178fs*6(1)|p.P177_E180delPHHE(1)|p.R42fs*24(1)|p.E171fs*1(1)|p.R174fs*3(1)|p.H178_H179>QY(1)|p.E171fs*61(1)		large_intestine(4656)|breast(2429)|upper_aerodigestive_tract(2212)|lung(2028)|ovary(1592)|oesophagus(1462)|haematopoietic_and_lymphoid_tissue(1228)|stomach(1136)|urinary_tract(1114)|central_nervous_system(1085)|liver(805)|skin(694)|pancreas(375)|biliary_tract(247)|soft_tissue(209)|prostate(194)|endometrium(150)|bone(102)|vulva(79)|kidney(79)|cervix(68)|thyroid(54)|salivary_gland(43)|adrenal_gland(37)|peritoneum(33)|eye(24)|thymus(21)|genital_tract(16)|autonomic_ganglia(16)|small_intestine(14)|testis(11)|penis(10)|vagina(6)|meninges(5)|pituitary(4)|pleura(3)|gastrointestinal_tract_(site_indeterminate)(1)|NS(1)|Fallopian tube(1)|placenta(1)	22245		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		GCAGCGCTCATGGTGGGGGCA	0.642000		111	Mis|N|F		breast|colorectal|lung|sarcoma|adrenocortical|glioma|multiple other tumour types	breast|sarcoma|adrenocortical carcinoma|glioma|multiple other tumour types		Other_conserved_DNA_damage_response_genes	Hereditary_Adrenocortical_Cancer|Endometrial_Cancer_Familial_Clustering_of|Hereditary_Breast-Ovarian_Cancer_non-BRCA1/2|Li-Fraumeni_syndrome|Osteosarcoma_Familial_Clustering_of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			26	18					0	0	0.005443	0	0
MYH2	4620	broad.mit.edu	37	17	10432154	10432154	+	Missense_Mutation	SNP	C	G	G			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr17:10432154C>G	uc010coi.2	-	27	3725	c.3597G>C	c.(3595-3597)AGG>AGC	p.R1199S	uc002gml.1_Intron|MYH2_uc002gmp.3_Missense_Mutation_p.R1199S|MYH2_uc010coj.2_Intron	NM_001100112	NP_001093582	Q9UKX2	MYH2_HUMAN	myosin heavy chain IIa	1199	Potential.				muscle filament sliding	muscle myosin complex|myosin filament|sarcomere	actin binding|ATP binding|calmodulin binding|microfilament motor activity|structural constituent of muscle			ovary(5)|pancreas(4)|skin(3)|lung(1)|kidney(1)	14						CATGCTTCTTCCTCAGGGTGG	0.552000													5	88					0	0	0.000602	0	0
UNC45B	146862	broad.mit.edu	37	17	33475300	33475300	+	Silent	SNP	G	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr17:33475300G>A	uc002hja.2	+	2	115	c.18G>A	c.(16-18)GCG>GCA	p.A6A	UNC45B_uc002hjb.2_Silent_p.A6A|UNC45B_uc002hjc.2_Silent_p.A6A|UNC45B_uc010cto.2_Silent_p.A6A	NM_173167	NP_775259	Q8IWX7	UN45B_HUMAN	cardiomyopathy associated 4 isoform 1	6	TPR 1.				cell differentiation|muscle organ development	cytosol	binding			ovary(3)|central_nervous_system(2)|breast(1)	6		Ovarian(249;0.17)				AGGTGGAAGCGGTACAGCTGA	0.612000													15	32					0	0	0.004007	0	0
XAB2	56949	broad.mit.edu	37	19	7686177	7686177	+	Missense_Mutation	SNP	C	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr19:7686177C>T	uc002mgx.2	-	13	1650	c.1624G>A	c.(1624-1626)GAG>AAG	p.E542K		NM_020196	NP_064581	Q9HCS7	SYF1_HUMAN	XPA binding protein 2	542	HAT 11.				transcription, DNA-dependent|transcription-coupled nucleotide-excision repair	catalytic step 2 spliceosome|nucleoplasm	protein binding			central_nervous_system(2)|breast(1)|skin(1)	4						ATGCCGCGCTCGTACGCCTGT	0.607000								Direct_reversal_of_damage|NER					11	35					0	0	0.010729	0	0
PIH1D1	55011	broad.mit.edu	37	19	49954795	49954795	+	Nonsense_Mutation	SNP	C	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr19:49954795C>A	uc002pns.2	-	1	321	c.37G>T	c.(37-39)GAG>TAG	p.E13*	PIH1D1_uc010yap.1_Nonsense_Mutation_p.E13*|PIH1D1_uc010yaq.1_Nonsense_Mutation_p.E13*|ALDH16A1_uc002pnt.2_5'Flank|ALDH16A1_uc010yar.1_5'Flank|ALDH16A1_uc010yas.1_5'Flank|ALDH16A1_uc010yat.1_5'Flank	NM_017916	NP_060386	Q9NWS0	PIHD1_HUMAN	NOP17	13					box C/D snoRNP assembly	pre-snoRNP complex					0		all_lung(116;5.39e-06)|Lung NSC(112;1.97e-05)|all_neural(266;0.0966)|Ovarian(192;0.15)		OV - Ovarian serous cystadenocarcinoma(262;0.00152)|GBM - Glioblastoma multiforme(486;0.0244)		GCCTCCGCCTCGCTTAGCCCC	0.607000													7	34					0.00400662	0.00434051	0.004007	1	0
WASH2P	375260	broad.mit.edu	37	2	114355998	114355998	+	Missense_Mutation	SNP	C	G	G			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr2:114355998C>G	uc002tkh.2	+	5	674	c.616C>G	c.(616-618)CAC>GAC	p.H206D	WASH2P_uc002tka.2_RNA|WASH2P_uc002tkb.2_RNA|WASH2P_uc002tkd.2_RNA	NM_182905	NP_878908			WAS protein family homolog 1												0						CCAAGGTGGGCACTTGATGTC	0.612000													2	5					0	0	0.004672	0	0
IDH1	3417	broad.mit.edu	37	2	209113112	209113112	+	Missense_Mutation	SNP	C	T	T	rs121913500		TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr2:209113112C>T	uc002vcs.2	-	4	641	c.395G>A	c.(394-396)CGT>CAT	p.R132H	IDH1_uc002vct.2_Missense_Mutation_p.R132H|IDH1_uc002vcu.2_Missense_Mutation_p.R132H	NM_005896	NP_005887	O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132		Substrate.	R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(2023)|p.R132C(344)|p.R132?(210)|p.R132G(117)|p.R132S(79)|p.R132L(58)|p.R132V(1)|p.G131_R132>VL(1)		central_nervous_system(2156)|haematopoietic_and_lymphoid_tissue(606)|bone(74)|thyroid(22)|large_intestine(4)|skin(2)|prostate(2)|autonomic_ganglia(1)|soft_tissue(1)	2868				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		ATAAGCATGACGACCTATGAT	0.393000			Mis		gliobastoma 								17	60					0	0	0.004990	0	0
JAG1	182	broad.mit.edu	37	20	10622192	10622192	+	Silent	SNP	C	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr20:10622192C>T	uc002wnw.2	-	23	3348	c.2832G>A	c.(2830-2832)GTG>GTA	p.V944V	JAG1_uc010gcd.1_Silent_p.V502V	NM_000214	NP_000205	P78504	JAG1_HUMAN	jagged 1 precursor	944	Extracellular (Potential).				angiogenesis|cell communication|cell fate determination|endothelial cell differentiation|hemopoiesis|keratinocyte differentiation|myoblast differentiation|Notch receptor processing|Notch signaling pathway|regulation of cell migration|regulation of cell proliferation	extracellular region|integral to plasma membrane	calcium ion binding|growth factor activity|Notch binding|structural molecule activity			lung(3)|ovary(2)|central_nervous_system(2)|breast(1)|pancreas(1)	9						ACTTTGTCTTCACCGGCTGGA	0.537000									Alagille_Syndrome				5	160					0	0	0.001168	0	0
CSRP2BP	57325	broad.mit.edu	37	20	18139760	18139760	+	Missense_Mutation	SNP	C	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr20:18139760C>T	uc002wqj.2	+	5	1155	c.533C>T	c.(532-534)GCA>GTA	p.A178V	CSRP2BP_uc002wqk.2_Missense_Mutation_p.A50V|CSRP2BP_uc010zru.1_Missense_Mutation_p.A50V	NM_020536	NP_065397	Q9H8E8	CSR2B_HUMAN	CSRP2 binding protein	178					histone H3 acetylation	Ada2/Gcn5/Ada3 transcription activator complex|cytoplasm	LIM domain binding|N-acetyltransferase activity			lung(3)|ovary(2)|skin(1)	6						AGCACCGTGGCAGGTTGCCTC	0.468000													13	34					0	0	0.006122	0	0
NECAB3	63941	broad.mit.edu	37	20	32246615	32246615	+	Missense_Mutation	SNP	A	C	C			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr20:32246615A>C	uc002wzn.3	-	9	1011	c.905T>G	c.(904-906)GTC>GGC	p.V302G	NECAB3_uc002wzl.2_Missense_Mutation_p.V47G|NECAB3_uc002wzm.3_Missense_Mutation_p.V268G|NECAB3_uc002wzo.3_RNA|NECAB3_uc002wzp.3_Missense_Mutation_p.V195G|NECAB3_uc002wzq.3_Missense_Mutation_p.V250G|NECAB3_uc002wzr.3_RNA|NECAB3_uc010geo.2_Missense_Mutation_p.V268G	NM_031232	NP_112509	Q96P71	NECA3_HUMAN	N-terminal EF-hand calcium binding protein 3	302					antibiotic biosynthetic process|protein metabolic process|protein secretion|regulation of amyloid precursor protein biosynthetic process	endoplasmic reticulum membrane|Golgi cis cisterna|nucleus	calcium ion binding|oxidoreductase activity|protein binding			lung(1)	1						TGCCACCTGGACCTGCCTCTG	0.672000													5	15					0	0	0.003080	0	0
FOXP1	27086	broad.mit.edu	37	3	71096104	71096104	+	Missense_Mutation	SNP	G	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr3:71096104G>A	uc003dol.2	-	6	976	c.653C>T	c.(652-654)CCT>CTT	p.P218L	FOXP1_uc003dom.2_Missense_Mutation_p.P142L|FOXP1_uc003don.2_RNA|FOXP1_uc003doo.2_Missense_Mutation_p.P218L|FOXP1_uc003dop.2_Missense_Mutation_p.P218L|FOXP1_uc003doq.1_Missense_Mutation_p.P217L|FOXP1_uc003doi.2_Missense_Mutation_p.P118L|FOXP1_uc003doj.2_Missense_Mutation_p.P118L|FOXP1_uc003dok.2_Missense_Mutation_p.P31L	NM_032682	NP_116071	Q9H334	FOXP1_HUMAN	forkhead box P1 isoform 1	218	Gln-rich.				cardiac muscle cell differentiation|embryo development|immunoglobulin V(D)J recombination|pattern specification process|positive regulation of epithelial cell proliferation involved in lung morphogenesis|positive regulation of immunoglobulin production|positive regulation of mesenchymal cell proliferation|pre-B cell differentiation|regulation of sequence-specific DNA binding transcription factor activity|skeletal muscle tissue development|smooth muscle tissue development	cytoplasm|transcription factor complex	chromatin binding|DNA bending activity|double-stranded DNA binding|promoter binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|zinc ion binding			ovary(1)|lung(1)	2		Lung NSC(201;4.62e-05)|Prostate(10;0.0181)|Hepatocellular(537;0.186)|Myeloproliferative disorder(1037;0.209)		BRCA - Breast invasive adenocarcinoma(55;1.17e-05)|Epithelial(33;1.39e-05)|LUSC - Lung squamous cell carcinoma(21;2.35e-05)|Lung(16;4.26e-05)		TTGAGCAAGAGGTTGAAGGGG	0.502000			T	PAX5	ALL								18	281					0	0	0.004990	0	0
SLC33A1	9197	broad.mit.edu	37	3	155571395	155571395	+	Missense_Mutation	SNP	G	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr3:155571395G>A	uc003fan.3	-	1	773	c.392C>T	c.(391-393)GCG>GTG	p.A131V	SLC33A1_uc003fao.1_Missense_Mutation_p.A131V	NM_004733	NP_004724	O00400	ACATN_HUMAN	acetyl-coenzyme A transporter	131	Helical; (Potential).				cell death|transmembrane transport	endoplasmic reticulum membrane|Golgi membrane|integral to plasma membrane|membrane fraction	acetyl-CoA transporter activity			ovary(2)|large_intestine(1)|pancreas(1)	4			Lung(72;0.11)|LUSC - Lung squamous cell carcinoma(72;0.114)			AACGTAGACCGCATCAACCAA	0.438000													3	43					0	0	0.004672	0	0
C3orf70	285382	broad.mit.edu	37	3	184870438	184870438	+	Silent	SNP	G	A	A			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr3:184870438G>A	uc003fpd.2	-	1	365	c.174C>T	c.(172-174)TGC>TGT	p.C58C		NM_001025266	NP_001020437	A6NLC5	CC070_HUMAN	hypothetical protein LOC285382	58											0						CTAGGTGACAGCACCAGTGCA	0.692000													2	6					0	0	0.004672	0	0
TDO2	6999	broad.mit.edu	37	4	156831281	156831281	+	Missense_Mutation	SNP	A	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr4:156831281A>T	uc003ipf.1	+	6	600	c.536A>T	c.(535-537)CAT>CTT	p.H179L		NM_005651	NP_005642	P48775	T23O_HUMAN	tryptophan 2,3-dioxygenase	179					tryptophan catabolic process to kynurenine	cytosol	tryptophan 2,3-dioxygenase activity				0	all_hematologic(180;0.24)	Renal(120;0.0854)		KIRC - Kidney renal clear cell carcinoma(143;0.0455)|Kidney(143;0.0568)|COAD - Colon adenocarcinoma(41;0.141)	L-Tryptophan(DB00150)	AACAGAAGACATTATCGTGAT	0.373000													11	128					0	0	0.013537	0	0
ACSL1	2180	broad.mit.edu	37	4	185679015	185679015	+	Missense_Mutation	SNP	C	G	G			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr4:185679015C>G	uc003iww.2	-	19	2136	c.1842G>C	c.(1840-1842)AAG>AAC	p.K614N	ACSL1_uc011ckm.1_Missense_Mutation_p.K443N|ACSL1_uc003iwt.1_Missense_Mutation_p.K614N|ACSL1_uc003iwu.1_Missense_Mutation_p.K614N|ACSL1_uc011ckn.1_Missense_Mutation_p.K580N|ACSL1_uc003iws.1_Missense_Mutation_p.K174N	NM_001995	NP_001986	P33121	ACSL1_HUMAN	acyl-CoA synthetase long-chain family member 1	614	Cytoplasmic (Potential).				digestion|fatty acid metabolic process|long-chain fatty-acyl-CoA biosynthetic process|regulation of fatty acid oxidation|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane|microsome|mitochondrial outer membrane|peroxisomal membrane	ATP binding|long-chain fatty acid-CoA ligase activity			ovary(2)	2		all_lung(41;7.57e-14)|Lung NSC(41;1.81e-13)|Colorectal(36;0.00172)|Hepatocellular(41;0.00826)|Renal(120;0.00988)|Prostate(90;0.0235)|all_hematologic(60;0.0315)|all_neural(102;0.107)|Medulloblastoma(177;0.146)		all cancers(43;1.33e-28)|Epithelial(43;5.3e-25)|OV - Ovarian serous cystadenocarcinoma(60;4.88e-11)|Colorectal(24;3.59e-06)|STAD - Stomach adenocarcinoma(60;2.72e-05)|GBM - Glioblastoma multiforme(59;2.83e-05)|BRCA - Breast invasive adenocarcinoma(30;7.66e-05)|COAD - Colon adenocarcinoma(29;0.000538)|LUSC - Lung squamous cell carcinoma(40;0.008)|READ - Rectum adenocarcinoma(43;0.0419)	Adenosine monophosphate(DB00131)|Adenosine triphosphate(DB00171)	CAAATCCTCTCTTTTGGGCCC	0.408000													6	127					0	0	0.004482	0	0
OR2B6	26212	broad.mit.edu	37	6	27925799	27925799	+	Nonsense_Mutation	SNP	C	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr6:27925799C>T	uc011dkx.1	+	1	781	c.781C>T	c.(781-783)CAA>TAA	p.Q261*		NM_012367	NP_036499	P58173	OR2B6_HUMAN	olfactory receptor, family 2, subfamily B,	261	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			skin(1)	1						TGTGTACCTGCAACCACCTTC	0.448000													24	119					0	0	0.002780	0	0
HSPA1L	3305	broad.mit.edu	37	6	31778479	31778479	+	Missense_Mutation	SNP	G	T	T			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr6:31778479G>T	uc003nxh.2	-	2	1454	c.1271C>A	c.(1270-1272)ACC>AAC	p.T424N	HSPA1L_uc010jte.2_Missense_Mutation_p.T424N	NM_005527	NP_005518	P34931	HS71L_HUMAN	heat shock 70kDa protein 1-like	424				T -> P (in Ref. 1; AAA63228).	response to unfolded protein		ATP binding			ovary(3)|pleura(1)|kidney(1)|skin(1)	6						TGTCTGCTTGGTGGGGATGGT	0.602000													15	116					2.23348e-06	2.72206e-06	0.004007	1	0
LGSN	51557	broad.mit.edu	37	6	63990534	63990534	+	Missense_Mutation	SNP	A	G	G			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr6:63990534A>G	uc003peh.2	-	4	956	c.922T>C	c.(922-924)TTT>CTT	p.F308L	LGSN_uc003pei.2_Intron	NM_016571	NP_057655	Q5TDP6	LGSN_HUMAN	lengsin, lens protein with glutamine synthetase	308					glutamine biosynthetic process		glutamate-ammonia ligase activity			skin(2)	2					L-Glutamic Acid(DB00142)	GAATCACAAAATCCAGTCTCA	0.428000													10	50					0	0	0.008291	0	0
LOC442421	442421	broad.mit.edu	37	9	66499770	66499770	+	Missense_Mutation	SNP	G	T	T	rs75046133		TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr9:66499770G>T	uc004aee.1	+	1	580	c.580G>T	c.(580-582)GCC>TCC	p.A194S	LOC442421_uc004aed.1_RNA					Homo sapiens hypothetical LOC442421, mRNA (cDNA clone IMAGE:40031134).												0						CAACCTGGTGGCCATCGTGGT	0.582000													5	76					3.86212e-05	4.43008e-05	0.008291	1	0
TPTE	7179	broad.mit.edu	37	21	10944697	10944697	+	Frame_Shift_Del	DEL	A	-	-			TCGA-CS-6290-01A-11D-1705-08	TCGA-CS-6290-10A-01D-1705-08									Somatic	Phase_I	Capture				Illumina GAIIx	9a31a094-fbeb-44ff-a939-16f71a0ba8d8	e6c5bbe0-666a-406b-bc8f-de3d71f88961	g.chr21:10944697delA	uc002yip.1	-	11	905	c.537delT	c.(535-537)TTTfs	p.F179fs	TPTE_uc002yis.1_RNA|TPTE_uc002yiq.1_Frame_Shift_Del_p.F161fs|TPTE_uc002yir.1_Frame_Shift_Del_p.F141fs|TPTE_uc010gkv.1_Frame_Shift_Del_p.F41fs	NM_199261	NP_954870	P56180	TPTE_HUMAN	transmembrane phosphatase with tensin homology	179	Helical; (Potential).				signal transduction	integral to membrane	ion channel activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity			ovary(2)|lung(1)|breast(1)|skin(1)	5			Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		ACTTAATGTCAAAAAAAATGT	0.299													10	302	---	---	---	---					
