Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	isArtifactMode	oxoGCut
F13B	2165	broad.mit.edu	37	1	197036317	197036317	+	Missense_Mutation	SNP	T	C	C			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr1:197036317T>C	uc001gtt.1	-	1	81	c.37A>G	c.(37-39)ATA>GTA	p.I13V		NM_001994	NP_001985	P05160	F13B_HUMAN	coagulation factor XIII B subunit precursor	13					blood coagulation	extracellular region				upper_aerodigestive_tract(1)|central_nervous_system(1)|skin(1)	3						CCTGAGATTATCAATATGATG	0.299000													9	69					0	0	0	0
HSD17B7P2	158160	broad.mit.edu	37	10	38654432	38654432	+	Missense_Mutation	SNP	A	G	G	rs2257765		TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr10:38654432A>G	uc010qex.1	+	5	599	c.524A>G	c.(523-525)AAT>AGT	p.N175S	HSD17B7P2_uc001izq.2_RNA|HSD17B7P2_uc001izo.1_RNA|HSD17B7P2_uc001izp.1_Missense_Mutation_p.N173S					SubName: Full=cDNA FLJ60462, highly similar to 3-keto-steroid reductase (EC 1.1.1.270);												0						TCATCTCGCAATGCAAGGAAA	0.453000													4	49					0	0	0	0
GDF10	2662	broad.mit.edu	37	10	48429292	48429292	+	Silent	SNP	G	A	A			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr10:48429292G>A	uc001jfb.2	-	2	1050	c.594C>T	c.(592-594)CGC>CGT	p.R198R	GDF10_uc009xnp.2_Silent_p.R197R|GDF10_uc009xnq.1_Silent_p.R198R	NM_004962	NP_004953	P55107	BMP3B_HUMAN	growth differentiation factor 10 precursor	198					growth|skeletal system development|transforming growth factor beta receptor signaling pathway	extracellular space	cytokine activity|growth factor activity			lung(1)|central_nervous_system(1)	2						GCCACAGGCCGCGCGGTGGGG	0.721000													24	24					0	0	0	0
ACVR1B	91	broad.mit.edu	37	12	52387841	52387841	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr12:52387841C>T	uc001rzn.2	+	9	1507	c.1465C>T	c.(1465-1467)CGC>TGC	p.R489C	ACVR1B_uc010snn.1_Missense_Mutation_p.R530C	NM_004302	NP_004293	P36896	ACV1B_HUMAN	activin A receptor, type IB isoform a precursor	489	Protein kinase.|Cytoplasmic (Potential).				G1/S transition of mitotic cell cycle|induction of apoptosis|negative regulation of cell growth|peptidyl-threonine phosphorylation|positive regulation of activin receptor signaling pathway|positive regulation of erythrocyte differentiation|protein autophosphorylation|transmembrane receptor protein serine/threonine kinase signaling pathway	cell surface	activin receptor activity, type I|ATP binding|metal ion binding|SMAD binding|transforming growth factor beta receptor activity|ubiquitin protein ligase binding			pancreas(4)|breast(2)|ovary(1)|lung(1)|kidney(1)	9				BRCA - Breast invasive adenocarcinoma(357;0.104)	Adenosine triphosphate(DB00171)	GACGGCCCTGCGCATCAAGAA	0.612000													20	73					0	0	0	0
Unknown	0	broad.mit.edu	37	15	102305084	102305084	+	5'Flank	SNP	T	C	C			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr15:102305084T>C	uc002cbx.1	-						uc002ccc.1_5'Flank|uc010uth.1_RNA|uc002cci.2_5'Flank|uc002ccj.2_5'Flank|uc002cck.2_5'Flank|uc002ccl.1_5'Flank|uc002ccm.1_5'Flank					DQ582460																		GACATCAACATGAACACCATC	0.632000													4	31					0	0	0	0
Unknown	0	broad.mit.edu	37	15	102305092	102305092	+	5'Flank	SNP	A	G	G			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr15:102305092A>G	uc002cbx.1	-						uc002ccc.1_5'Flank|uc010uth.1_RNA|uc002cci.2_5'Flank|uc002ccj.2_5'Flank|uc002cck.2_5'Flank|uc002ccl.1_5'Flank|uc002ccm.1_5'Flank					DQ582460																		CATGAACACCATCAGCACAGC	0.632000													3	30					0	0	0	0
CYLD	1540	broad.mit.edu	37	16	50815182	50815182	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr16:50815182A>T	uc002egp.1	+	10	1959	c.1544A>T	c.(1543-1545)GAT>GTT	p.D515V	CYLD_uc002ego.2_Missense_Mutation_p.D512V|CYLD_uc010cbs.1_Missense_Mutation_p.D512V|CYLD_uc002egq.1_Missense_Mutation_p.D512V|CYLD_uc002egr.1_Missense_Mutation_p.D512V|CYLD_uc002egs.1_Missense_Mutation_p.D512V	NM_015247	NP_056062	Q9NQC7	CYLD_HUMAN	ubiquitin carboxyl-terminal hydrolase CYLD	515	CAP-Gly 3.|Interaction with TRIP.|Interaction with IKBKG/NEMO.				cell cycle|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of NF-kappaB import into nucleus|negative regulation of NF-kappaB transcription factor activity|negative regulation of type I interferon production|protein K63-linked deubiquitination|regulation of microtubule cytoskeleton organization|regulation of mitotic cell cycle|translation|ubiquitin-dependent protein catabolic process|Wnt receptor signaling pathway	cytosol|extrinsic to internal side of plasma membrane|microtubule|perinuclear region of cytoplasm|ribosome	proline-rich region binding|protein kinase binding|structural constituent of ribosome|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|zinc ion binding			skin(19)|large_intestine(3)|haematopoietic_and_lymphoid_tissue(3)|central_nervous_system(3)	28		all_cancers(37;0.0156)				GGCTGTACGGATGGAACCTTC	0.448000			Mis|N|F|S		cylindroma	cylindroma			Familial_Cylindromatosis|Multiple_Trichoepithelioma_Familial				42	31					0	0	0	0
DNAH9	1770	broad.mit.edu	37	17	11774927	11774927	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr17:11774927G>A	uc002gne.2	+	52	10134	c.10066G>A	c.(10066-10068)GCT>ACT	p.A3356T	DNAH9_uc010coo.2_Missense_Mutation_p.A2650T	NM_001372	NP_001363	Q9NYC9	DYH9_HUMAN	dynein, axonemal, heavy chain 9 isoform 2	3356					cell projection organization|cellular component movement|microtubule-based movement|spermatogenesis	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			skin(10)|ovary(4)|breast(3)|central_nervous_system(2)|pancreas(1)	20		Breast(5;0.0122)|all_epithelial(5;0.131)		Colorectal(4;6.88e-05)|COAD - Colon adenocarcinoma(4;0.000813)|READ - Rectum adenocarcinoma(10;0.157)		TGGAGGACTCGCTTCTGAAAA	0.493000													26	46					0	0	0	0
Unknown	0	broad.mit.edu	37	17	39296167	39296167	+	RNA	SNP	A	G	G			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr17:39296167A>G	uc010cxk.1	-	1		c.537T>C								Homo sapiens partial mRNA for keratin associated protein 4.6 (KRTAP4.6 gene).																		GGCAGGTGGAAATGACACAGG	0.478000													3	12					0	0	0	0
TBC1D3P2	440452	broad.mit.edu	37	17	60342280	60342280	+	RNA	SNP	C	T	T	rs80012429		TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr17:60342280C>T	uc010woz.1	-	14		c.1849G>A				NR_027486				Homo sapiens cDNA FLJ60189 complete cds, highly similar to TBC1 domain family member 3.												0						TTAATACATTCTCATAAGTTT	0.488000													5	119					0	0	0	0
CD97	976	broad.mit.edu	37	19	14507206	14507206	+	Silent	SNP	C	T	T			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr19:14507206C>T	uc002myl.2	+	5	522	c.399C>T	c.(397-399)TGC>TGT	p.C133C	CD97_uc002mym.2_Silent_p.C133C|CD97_uc002myn.2_Intron	NM_078481	NP_510966	P48960	CD97_HUMAN	CD97 antigen isoform 1 precursor	133	Extracellular (Potential).|EGF-like 3; calcium-binding (Potential).				cell adhesion|cell-cell signaling|cellular component movement|immune response|inflammatory response|neuropeptide signaling pathway	extracellular space|integral to plasma membrane	calcium ion binding|G-protein coupled receptor activity|protein binding			ovary(3)|breast(1)	4						ACGGCACCTGCGTCAACACCC	0.567000													9	117					0	0	0	0
EMR2	30817	broad.mit.edu	37	19	14877869	14877869	+	Silent	SNP	G	A	A	rs138601089		TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr19:14877869G>A	uc002mzp.1	-	6	864	c.408C>T	c.(406-408)TGC>TGT	p.C136C	EMR2_uc010dzs.1_5'Flank|EMR2_uc010xnw.1_Silent_p.C136C|EMR2_uc002mzo.1_Silent_p.C136C|EMR2_uc002mzq.1_Silent_p.C136C|EMR2_uc002mzr.1_Silent_p.C136C|EMR2_uc002mzs.1_Intron|EMR2_uc002mzt.1_Intron|EMR2_uc002mzu.1_Intron|EMR2_uc010xnx.1_RNA|EMR2_uc010xny.1_RNA	NM_013447	NP_038475	Q9UHX3	EMR2_HUMAN	egf-like module containing, mucin-like, hormone	136	Extracellular (Potential).|EGF-like 3; calcium-binding.				cell adhesion|neuropeptide signaling pathway	integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity			lung(2)|ovary(1)|skin(1)	4						GGGTGTTGACGCAGGTGCCGT	0.582000													6	7					0	0	0	0
FN1	2335	broad.mit.edu	37	2	216262570	216262570	+	Missense_Mutation	SNP	A	C	C			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr2:216262570A>C	uc002vfa.2	-	22	3616	c.3350T>G	c.(3349-3351)CTG>CGG	p.L1117R	FN1_uc002vfb.2_Missense_Mutation_p.L1117R|FN1_uc002vfc.2_Missense_Mutation_p.L1117R|FN1_uc002vfd.2_Missense_Mutation_p.L1117R|FN1_uc002vfe.2_Missense_Mutation_p.L1117R|FN1_uc002vff.2_Missense_Mutation_p.L1117R|FN1_uc002vfg.2_Missense_Mutation_p.L1117R|FN1_uc002vfh.2_Missense_Mutation_p.L1117R|FN1_uc002vfi.2_Missense_Mutation_p.L1117R|FN1_uc002vfj.2_Missense_Mutation_p.L1117R	NM_212482	NP_997647	P02751	FINC_HUMAN	fibronectin 1 isoform 1 preproprotein	1117	|Fibronectin type-III 6.				acute-phase response|angiogenesis|leukocyte migration|peptide cross-linking|platelet activation|platelet degranulation|regulation of cell shape|substrate adhesion-dependent cell spreading	ER-Golgi intermediate compartment|fibrinogen complex|platelet alpha granule lumen|proteinaceous extracellular matrix	collagen binding|extracellular matrix structural constituent|heparin binding			central_nervous_system(7)|large_intestine(2)|breast(2)|ovary(1)|pancreas(1)	13		Renal(323;0.127)		Epithelial(149;9.59e-07)|all cancers(144;0.000174)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00948)	Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)	TCGTACACCCAGCTAGAGGAA	0.468000													21	44					0	0	0	0
COL6A3	1293	broad.mit.edu	37	2	238275793	238275793	+	Silent	SNP	C	A	A			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr2:238275793C>A	uc002vwl.2	-	11	5322	c.5037G>T	c.(5035-5037)GGG>GGT	p.G1679G	COL6A3_uc002vwo.2_Silent_p.G1473G|COL6A3_uc010znj.1_Silent_p.G1072G	NM_004369	NP_004360	P12111	CO6A3_HUMAN	alpha 3 type VI collagen isoform 1 precursor	1679	VWFA 9.|Nonhelical region.		G -> E (in BM).		axon guidance|cell adhesion|muscle organ development	collagen type VI|extracellular space	serine-type endopeptidase inhibitor activity			ovary(8)|central_nervous_system(6)|skin(2)|upper_aerodigestive_tract(1)|pancreas(1)	18		Breast(86;0.000301)|Renal(207;0.000966)|all_hematologic(139;0.067)|Ovarian(221;0.0694)|all_lung(227;0.0943)|Melanoma(123;0.203)		Epithelial(121;1.23e-21)|OV - Ovarian serous cystadenocarcinoma(60;1.34e-10)|Kidney(56;5.71e-09)|KIRC - Kidney renal clear cell carcinoma(57;1.51e-07)|BRCA - Breast invasive adenocarcinoma(100;0.00025)|Lung(119;0.0142)|LUSC - Lung squamous cell carcinoma(224;0.034)		ACTGGACAAGCCCCACTTGGA	0.468000													14	16					6.81908e-15	1.39004e-14	1	0
LOC96610	96610	broad.mit.edu	37	22	22664606	22664606	+	RNA	SNP	A	G	G			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr22:22664606A>G	uc011aim.1	+	31		c.2121A>G			LOC96610_uc011aiq.1_RNA					Parts of antibodies, mostly variable regions.												0						GTCTTCATGCAAACTTGGTAT	0.398000													3	12					0	0	0	0
C22orf42	150297	broad.mit.edu	37	22	32554980	32554980	+	Missense_Mutation	SNP	T	C	C			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr22:32554980T>C	uc003amd.2	-	1	264	c.223A>G	c.(223-225)ATG>GTG	p.M75V		NM_001010859	NP_001010859	Q6IC83	CV042_HUMAN	chromosome 22 open reading frame 42	75										ovary(1)|skin(1)	2						CCTTTGGACATCTTCAGCATC	0.547000													68	151					0	0	0	0
BTC	685	broad.mit.edu	37	4	75681110	75681110	+	Silent	SNP	C	T	T			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr4:75681110C>T	uc003hig.2	-	3	587	c.240G>A	c.(238-240)GGG>GGA	p.G80G		NM_001729	NP_001720	P35070	BTC_HUMAN	betacellulin precursor	80	Extracellular (Potential).|EGF-like.				positive regulation of cell division|positive regulation of cell proliferation	extracellular space|integral to membrane|plasma membrane|soluble fraction	epidermal growth factor receptor binding|growth factor activity			central_nervous_system(1)|skin(1)	2			Lung(101;0.219)			AGCGGCATCTCCCTTTGATGC	0.532000													47	85					0	0	0	0
CD74	972	broad.mit.edu	37	5	149784722	149784722	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr5:149784722A>T	uc003lsc.2	-	5	474	c.463T>A	c.(463-465)TAC>AAC	p.Y155N	CD74_uc003lsb.2_Missense_Mutation_p.Y19N|CD74_uc003lse.2_Intron|CD74_uc003lsd.2_Missense_Mutation_p.Y155N|CD74_uc003lsf.1_Missense_Mutation_p.Y155N	NM_001025159	NP_001020330	P04233	HG2A_HUMAN	CD74 antigen isoform a	155	Extracellular (Potential).				antigen processing and presentation of endogenous antigen|cell proliferation|immunoglobulin mediated immune response|intracellular protein transport|negative regulation of apoptosis|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of peptide secretion|positive regulation of B cell proliferation|positive regulation of chemokine (C-X-C motif) ligand 2 production|positive regulation of cytokine-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade|positive regulation of fibroblast proliferation|positive regulation of macrophage cytokine production|positive regulation of neutrophil chemotaxis|positive regulation of peptidyl-tyrosine phosphorylation|prostaglandin biosynthetic process|protein complex assembly|regulation of macrophage activation	endoplasmic reticulum membrane|Golgi apparatus|integral to membrane|lysosome|receptor complex	beta-amyloid binding|cytokine receptor activity|identical protein binding|MHC class II protein binding			breast(1)	1		all_hematologic(541;0.224)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			AGTGGCGGGTACACCTTCAGG	0.562000			T	ROS1	NSCLC								4	78					0	0	0	0
HLA-A	3105	broad.mit.edu	37	6	29910693	29910693	+	Missense_Mutation	SNP	A	G	G	rs41559716		TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr6:29910693A>G	uc003nol.2	+	2	233	c.233A>G	c.(232-234)CAG>CGG	p.Q78R	HLA-G_uc011dmb.1_Intron|HCG4P6_uc003nog.1_Intron|HLA-A_uc010jrq.2_5'UTR|HLA-A_uc003nok.2_5'UTR|HLA-A_uc003non.2_Missense_Mutation_p.Q78R|HLA-A_uc003noo.2_Missense_Mutation_p.Q78R|HLA-A_uc010jrr.2_Missense_Mutation_p.Q78R|HLA-A_uc003nom.2_5'UTR|HLA-A_uc010klp.2_Missense_Mutation_p.Q50R|HLA-A_uc011dmc.1_5'UTR|HLA-A_uc011dmd.1_5'Flank	NM_002116	NP_002107	P30443	1A01_HUMAN	major histocompatibility complex, class I, A	78	Extracellular (Potential).|Alpha-1.				antigen processing and presentation of peptide antigen via MHC class I|interferon-gamma-mediated signaling pathway|interspecies interaction between organisms|regulation of immune response|type I interferon-mediated signaling pathway	integral to plasma membrane|MHC class I protein complex	MHC class I receptor activity			upper_aerodigestive_tract(1)|ovary(1)	2						TGGATAGAGCAGGAGGGGCCG	0.657000									Melanoma_Familial_Clustering_of|Lichen_Sclerosis_et_Atrophicus_Familial_Clustering_of|Osteosarcoma_Familial_Clustering_of|Naso-/Oropharyngeal/Laryngeal_Cancer_Familial_Clustering_of	Multiple Myeloma(9;0.094)			4	9					0	0	0	0
BCLAF1	9774	broad.mit.edu	37	6	136599279	136599279	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr6:136599279A>G	uc003qgx.1	-	4	993	c.740T>C	c.(739-741)ATG>ACG	p.M247T	BCLAF1_uc003qgw.1_Missense_Mutation_p.M247T|BCLAF1_uc003qgy.1_Missense_Mutation_p.M245T|BCLAF1_uc011edc.1_RNA|BCLAF1_uc011edd.1_RNA|BCLAF1_uc011ede.1_Missense_Mutation_p.M245T	NM_014739	NP_055554	Q9NYF8	BCLF1_HUMAN	BCL2-associated transcription factor 1 isoform	247					induction of apoptosis|negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleolus	DNA binding|protein binding			ovary(1)	1	Colorectal(23;0.24)			GBM - Glioblastoma multiforme(68;0.00226)|OV - Ovarian serous cystadenocarcinoma(155;0.00331)		TGTACTGAGCATGGGAGCATC	0.453000													20	102					0	0	0	0
MPDZ	8777	broad.mit.edu	37	9	13219563	13219563	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr9:13219563A>T	uc010mia.1	-	7	1138	c.1081T>A	c.(1081-1083)TTG>ATG	p.L361M	MPDZ_uc010mhy.2_Missense_Mutation_p.L361M|MPDZ_uc010mhz.2_Missense_Mutation_p.L361M|MPDZ_uc011lmn.1_Missense_Mutation_p.L361M|MPDZ_uc003zlb.3_Missense_Mutation_p.L361M	NM_003829	NP_003820	O75970	MPDZ_HUMAN	multiple PDZ domain protein	361					interspecies interaction between organisms	apical plasma membrane|dendrite|postsynaptic density|postsynaptic membrane|synaptosome|tight junction	protein C-terminus binding			ovary(5)|central_nervous_system(1)	6				GBM - Glioblastoma multiforme(50;2.03e-06)		CTTACCCGCAACTCTGGTGTT	0.418000													17	23					0	0	0	0
ERAS	3266	broad.mit.edu	37	X	48687628	48687628	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chrX:48687628G>A	uc004dky.1	+	1	346	c.95G>A	c.(94-96)CGC>CAC	p.R32H		NM_181532	NP_853510	Q7Z444	RASE_HUMAN	ES cell expressed Ras precursor	32					small GTPase mediated signal transduction	intracellular|plasma membrane	GTP binding|GTPase activity			lung(4)|urinary_tract(1)	5						CAGGCACGCCGCAGGGATGTT	0.657000													5	17					0	0	0	0
Unknown	0	broad.mit.edu	37	19	53703995	53703995	+	IGR	DEL	T	-	-	rs113703393		TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr19:53703995delT								ZNF665 (7376 upstream) : ZNF677 (34643 downstream)																							TGTTTCCCCCttttttttttt	0.229													---	---	---							
SOX10	6663	broad.mit.edu	37	22	38370169	38370180	+	In_Frame_Del	DEL	GGGGTGGTTGGA	-	-			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr22:38370169_38370180delGGGGTGGTTGGA	uc003aun.1	-	4	1001_1012	c.723_734delTCCAACCACCCC	c.(721-735)CCTCCAACCACCCCG>CCG	p.241_245PPTTP>P	POLR2F_uc003aum.2_Intron|SOX10_uc003auo.1_In_Frame_Del_p.241_245PPTTP>P	NM_006941	NP_008872	P56693	SOX10_HUMAN	SRY (sex determining region Y)-box 10	241_245						cytoplasm|nucleus	DNA binding|identical protein binding|transcription coactivator activity				0	Melanoma(58;0.045)					CTCTGTCTTCGGGGTGGTTGGAGGGGTGGGTG	0.646													---	---	---							
Unknown	0	broad.mit.edu	37	4	184300740	184300750	+	IGR	DEL	CAATAGTTGAA	-	-	rs144058613		TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr4:184300740_184300750delCAATAGTTGAA								WWC2 (58813 upstream) : CDKN2AIP (65039 downstream)																							gagagcttcccaatagttgaacatgtggagg	0.005													---	---	---							
Unknown	0	broad.mit.edu	37	5	37086022	37086022	+	IGR	DEL	A	-	-			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr5:37086022delA								NIPBL (20102 upstream) : C5orf42 (20308 downstream)																							AATTAATAGGAAAAAAAAaaa	0.204													---	---	---							
SMAP1	60682	broad.mit.edu	37	6	71508370	71508370	+	Frame_Shift_Del	DEL	A	-	-			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr6:71508370delA	uc003pfr.2	+	6	754	c.506delA	c.(505-507)GAAfs	p.E169fs	SMAP1_uc011dxy.1_RNA|SMAP1_uc003pfs.2_Frame_Shift_Del_p.E142fs|SMAP1_uc010kao.2_Frame_Shift_Del_p.E142fs|SMAP1_uc010kap.2_Frame_Shift_Del_p.E159fs	NM_001044305	NP_001037770	Q8IYB5	SMAP1_HUMAN	stromal membrane-associated GTPase-activating	169					regulation of ARF GTPase activity	plasma membrane	ARF GTPase activator activity|zinc ion binding				0						aaagaaaaggaaaaaaaaaag	0.234													---	---	---							
Unknown	0	broad.mit.edu	37	6	160132356	160132373	+	IGR	DEL	CTCACACTGCTCTGACCT	-	-	rs79322534		TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr6:160132356_160132373delCTCACACTGCTCTGACCT								SOD2 (18003 upstream) : WTAP (15756 downstream)																							ataaccaccactcacactgctctgacctccataaccac	0.128													---	---	---							
NFIB	4781	broad.mit.edu	37	9	14125721	14125722	+	Frame_Shift_Del	DEL	AC	-	-			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr9:14125721_14125722delAC	uc003zle.2	-	7	1404_1405	c.969_970delGT	c.(967-972)TTGTTCfs	p.L323fs	NFIB_uc003zld.2_Frame_Shift_Del_p.L71fs|NFIB_uc003zlf.2_Frame_Shift_Del_p.L323fs|NFIB_uc011lmo.1_Frame_Shift_Del_p.L323fs	NM_005596	NP_005587	O00712	NFIB_HUMAN	nuclear factor I/B	323_324					anterior commissure morphogenesis|chondrocyte differentiation|Clara cell differentiation|commissural neuron axon guidance|DNA replication|glial cell differentiation|lung ciliated cell differentiation|negative regulation of DNA binding|negative regulation of epithelial cell proliferation involved in lung morphogenesis|negative regulation of mesenchymal cell proliferation involved in lung development|positive regulation of transcription from RNA polymerase II promoter|principal sensory nucleus of trigeminal nerve development|Type I pneumocyte differentiation|Type II pneumocyte differentiation	cerebellar mossy fiber|nucleolus|nucleus	RNA polymerase II transcription corepressor activity|sequence-specific DNA binding RNA polymerase II transcription factor activity				0				GBM - Glioblastoma multiforme(50;4.4e-08)|LUAD - Lung adenocarcinoma(58;0.119)|Lung(218;0.164)		GCAGAGCTGAACAATGGCTTTT	0.480			T	MYB|HGMA2	adenoid cystic carcinoma|lipoma								---	---	---							
Unknown	0	broad.mit.edu	37	9	133834150	133834152	+	IGR	DEL	CAC	-	-			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chr9:133834150_133834152delCAC								FIBCD1 (19695 upstream) : LAMC3 (50352 downstream)																							ccatcaccatcaccaccaccacc	0.000													---	---	---							
PLXNB3	5365	broad.mit.edu	37	X	153040467	153040468	+	Frame_Shift_Ins	INS	-	G	G			TCGA-D6-6827-01A-11D-1912-08	TCGA-D6-6827-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	059be8f9-9536-40c0-a751-5fe529a2f01f	fddb2e4f-1d76-4108-9c87-14b55cc52055	g.chrX:153040467_153040468insG	uc004fii.2	+	24	4238_4239	c.4064_4065insG	c.(4063-4065)GAGfs	p.E1355fs	PLXNB3_uc010nuk.2_Frame_Shift_Ins_p.E1378fs|PLXNB3_uc011mzd.1_Frame_Shift_Ins_p.E994fs|PLXNB3_uc004fij.1_RNA|SRPK3_uc004fik.2_5'Flank	NM_005393	NP_005384	Q9ULL4	PLXB3_HUMAN	plexin B3 isoform 1	1355	Cytoplasmic (Potential).				axon guidance	integral to membrane|intracellular|plasma membrane	protein binding|receptor activity			lung(1)	1	all_hematologic(71;4.25e-06)|all_lung(58;3.83e-05)|Lung NSC(58;5.54e-05)|Acute lymphoblastic leukemia(192;6.56e-05)					CCCAAGCCTGAGGGGCCAGGGG	0.688													---	---	---							
