Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	isArtifactMode	oxoGCut
ZC3H12A	80149	broad.mit.edu	37	1	37949128	37949128	+	Silent	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:37949128G>C	uc001cbb.3	+	6	1866	c.1716G>C	c.(1714-1716)GTG>GTC	p.V572V	ZC3H12A_uc001cbc.1_Silent_p.V367V	NM_025079	NP_079355	Q5D1E8	ZC12A_HUMAN	zinc finger CCCH-type containing 12A	572					angiogenesis|apoptosis|cell differentiation	cytoplasm|nucleus|plasma membrane	endonuclease activity|metal ion binding			ovary(2)	2		Myeloproliferative disorder(586;0.0255)|all_neural(195;0.164)				TGGAGGCTGTGATGGGGCGCT	0.657													8	46					0	0	0	0
KNCN	148930	broad.mit.edu	37	1	47016763	47016763	+	5'Flank	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:47016763C>G	uc001cpy.2	-						KNCN_uc009vyh.1_Missense_Mutation_p.G42A			A6PVL3	KNCN_HUMAN	SubName: Full=cDNA FLJ32011 fis, clone NT2RP7009507;							integral to membrane					0	Acute lymphoblastic leukemia(166;0.155)					AATAAAGACACCGCCCATGGC	0.632													7	110					0	0	0	0
CYP4Z2P	163720	broad.mit.edu	37	1	47351188	47351188	+	RNA	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:47351188G>T	uc001cqo.1	-	4		c.473C>A			CYP4Z2P_uc009vyn.1_RNA	NR_002788				Homo sapiens cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to CYTOCHROME P450 4A1 (EC 1.14.15.3).												0						TGCTGATGTTGAAGCCAGGTT	0.448													4	66					0.00909568	0.00969212	1	0
CYP4A22	284541	broad.mit.edu	37	1	47610609	47610609	+	Missense_Mutation	SNP	G	A	A	rs141856283		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:47610609G>A	uc001cqv.1	+	9	1240	c.1189G>A	c.(1189-1191)GTC>ATC	p.V397I	CYP4A22_uc009vyo.2_Missense_Mutation_p.V397I|CYP4A22_uc009vyp.2_Missense_Mutation_p.V299I	NM_001010969	NP_001010969	Q5TCH4	CP4AM_HUMAN	cytochrome P450, family 4, subfamily A,	397						endoplasmic reticulum membrane|microsome	alkane 1-monooxygenase activity|electron carrier activity|heme binding			skin(2)|ovary(1)|breast(1)	4						CAGCACTCCCGTCACCTTCCC	0.582													7	58					0	0	0	0
CACHD1	57685	broad.mit.edu	37	1	65099811	65099811	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:65099811G>A	uc001dbo.1	+	7	826	c.721G>A	c.(721-723)GAG>AAG	p.E241K	CACHD1_uc001dbp.1_5'UTR|CACHD1_uc001dbq.1_5'UTR	NM_020925	NP_065976	Q5VU97	CAHD1_HUMAN	cache domain containing 1	292	Extracellular (Potential).|VWFA.				calcium ion transport	integral to membrane				ovary(2)	2						AGCCACCAGTGAGACAAAAAG	0.473													7	70					0	0	0	0
PDE4B	5142	broad.mit.edu	37	1	66833700	66833700	+	Silent	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:66833700T>C	uc001dcn.2	+	15	1805	c.1614T>C	c.(1612-1614)GTT>GTC	p.V538V	PDE4B_uc009war.2_Silent_p.V446V|PDE4B_uc001dco.2_Silent_p.V538V|PDE4B_uc001dcp.2_Silent_p.V523V|PDE4B_uc001dcq.2_Silent_p.V366V|PDE4B_uc009was.2_Silent_p.V305V	NM_001037341	NP_001032418	Q07343	PDE4B_HUMAN	phosphodiesterase 4B isoform 1	538					signal transduction	cytosol|insoluble fraction|soluble fraction	3',5'-cyclic-AMP phosphodiesterase activity|metal ion binding			ovary(2)|central_nervous_system(1)	3					Adenosine monophosphate(DB00131)|Amrinone(DB01427)|Caffeine(DB00201)|Cilostazol(DB01166)|Dyphylline(DB00651)|Enprofylline(DB00824)|Papaverine(DB01113)|Pentoxifylline(DB00806)|Theophylline(DB00277)	CGAAGAAAGTTACAAGTTCAG	0.388													12	90					0	0	0	0
COL11A1	1301	broad.mit.edu	37	1	103355090	103355090	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:103355090C>G	uc001dul.2	-	59	4703	c.4385G>C	c.(4384-4386)GGT>GCT	p.G1462A	COL11A1_uc001duk.2_Missense_Mutation_p.G658A|COL11A1_uc001dum.2_Missense_Mutation_p.G1474A|COL11A1_uc001dun.2_Missense_Mutation_p.G1423A|COL11A1_uc009weh.2_Missense_Mutation_p.G1346A	NM_001854	NP_001845	P12107	COBA1_HUMAN	alpha 1 type XI collagen isoform A	1462	Triple-helical region.				collagen fibril organization|detection of mechanical stimulus involved in sensory perception of sound|visual perception	collagen type XI	extracellular matrix binding|extracellular matrix structural constituent|protein binding, bridging			ovary(6)|breast(3)|upper_aerodigestive_tract(1)|central_nervous_system(1)|pancreas(1)	12		all_epithelial(167;2.52e-07)|all_lung(203;3.11e-05)|Lung NSC(277;6.61e-05)|Breast(1374;0.181)		Lung(183;0.186)|all cancers(265;0.242)|Epithelial(280;0.248)		TCCTGGAGGACCAATCAGGCC	0.388													14	156					0	0	0	0
KCNA3	3738	broad.mit.edu	37	1	111216803	111216803	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:111216803G>A	uc001dzv.1	-	1	853	c.629C>T	c.(628-630)CCC>CTC	p.P210L		NM_002232	NP_002223	P22001	KCNA3_HUMAN	potassium voltage-gated channel, shaker-related	210						voltage-gated potassium channel complex	delayed rectifier potassium channel activity			ovary(4)|pancreas(1)	5		all_cancers(81;3.92e-06)|all_epithelial(167;1.28e-05)|all_lung(203;0.000199)|Lung NSC(277;0.000398)		Lung(183;0.0235)|Colorectal(144;0.0306)|all cancers(265;0.0752)|Epithelial(280;0.0821)|COAD - Colon adenocarcinoma(174;0.132)|LUSC - Lung squamous cell carcinoma(189;0.133)		GCGGGGCAAGGGCCGCTCCTC	0.677													4	55					0	0	0	0
PTGFRN	5738	broad.mit.edu	37	1	117487601	117487601	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:117487601C>T	uc001egv.1	+	3	856	c.719C>T	c.(718-720)GCC>GTC	p.A240V		NM_020440	NP_065173	Q9P2B2	FPRP_HUMAN	prostaglandin F2 receptor negative regulator	240	Ig-like C2-type 2.|Extracellular (Potential).					endoplasmic reticulum membrane|Golgi apparatus|integral to membrane	protein binding			liver(1)	1	Lung SC(450;0.225)	all_cancers(81;0.00104)|all_lung(203;8.97e-05)|all_epithelial(167;0.000139)|Lung NSC(69;0.000446)		Lung(183;0.0704)|LUSC - Lung squamous cell carcinoma(189;0.227)|Colorectal(144;0.248)		GCTCTGTCTGCCGACCAGGGC	0.657													3	55					0	0	0	0
NBPF7	343505	broad.mit.edu	37	1	120378772	120378772	+	Missense_Mutation	SNP	G	A	A	rs76727176	byFrequency	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:120378772G>A	uc010oxk.1	-	7	1595	c.974C>T	c.(973-975)ACG>ATG	p.T325M		NM_001047980	NP_001041445	P0C2Y1	NBPF7_HUMAN	hypothetical protein LOC343505	325	NBPF 2.					cytoplasm				ovary(1)|skin(1)	2	all_cancers(5;7.07e-10)|all_epithelial(5;1.62e-10)|all_neural(166;0.153)|Breast(55;0.234)	all_lung(203;3.66e-05)|Lung NSC(69;0.000192)|all_epithelial(167;0.0347)		Lung(183;0.0103)|LUSC - Lung squamous cell carcinoma(189;0.0544)		ACAAGAAGTCGTAACCCTTTC	0.488													4	85					0	0	0	0
PDE4DIP	9659	broad.mit.edu	37	1	144952292	144952292	+	Missense_Mutation	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:144952292T>C	uc001elw.3	-	4	718	c.427A>G	c.(427-429)AAA>GAA	p.K143E	NBPF10_uc009wir.2_Intron|NBPF9_uc010oye.1_Intron|NBPF9_uc010oyf.1_Intron|NBPF9_uc010oyg.1_Intron|PDE4DIP_uc001elk.1_Intron|PDE4DIP_uc001ell.1_Intron|PDE4DIP_uc001elm.3_Intron|PDE4DIP_uc001eln.3_Intron|PDE4DIP_uc001elo.2_Intron|PDE4DIP_uc001elx.3_Missense_Mutation_p.K209E|PDE4DIP_uc001emc.1_Missense_Mutation_p.K143E|PDE4DIP_uc001emd.1_Missense_Mutation_p.K143E|PDE4DIP_uc001emg.1_Missense_Mutation_p.K143E|PDE4DIP_uc001emh.2_Missense_Mutation_p.K280E	NM_014644	NP_055459	Q5VU43	MYOME_HUMAN	phosphodiesterase 4D interacting protein isoform	143					cellular protein complex assembly	centrosome|Golgi apparatus|myofibril|nucleus	enzyme binding			ovary(4)|haematopoietic_and_lymphoid_tissue(1)	5				Colorectal(2;0.0829)|COAD - Colon adenocarcinoma(2;0.126)		CCCTTCAGTTTCTCTGAGAGC	0.532			T	PDGFRB	MPD								3	122					0	0	0	0
TUFT1	7286	broad.mit.edu	37	1	151512818	151512818	+	Translation_Start_Site	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:151512818G>A	uc001eyl.2	+	1	38	c.-24G>A	c.(-26--22)GCGTG>GCATG		TUFT1_uc001eym.2_Translation_Start_Site|TUFT1_uc010pdf.1_Translation_Start_Site|TUFT1_uc010pdg.1_Translation_Start_Site	NM_020127	NP_064512	Q9NNX1	TUFT1_HUMAN	tuftelin 1 isoform 1						bone mineralization|odontogenesis	cytoplasm|extracellular region	structural constituent of tooth enamel				0	Ovarian(49;0.0273)|Hepatocellular(266;0.0997)|all_hematologic(923;0.127)|Melanoma(130;0.185)		LUSC - Lung squamous cell carcinoma(543;0.181)			GACAAGTGGCGTGTGTGCTGC	0.672											OREG0003907	type=REGULATORY REGION|Gene=TUFT1|Dataset=Stanford ENCODE Dataset|EvidenceSubtype=Transient transfection luciferase assay	21	92					0	0	0	0
NES	10763	broad.mit.edu	37	1	156640663	156640663	+	Missense_Mutation	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:156640663C>A	uc001fpq.2	-	4	3450	c.3317G>T	c.(3316-3318)GGA>GTA	p.G1106V		NM_006617	NP_006608	P48681	NEST_HUMAN	nestin	1106	Tail.				brain development|embryonic camera-type eye development|G2/M transition of mitotic cell cycle|negative regulation of apoptosis|positive regulation of intermediate filament depolymerization|positive regulation of neural precursor cell proliferation|stem cell proliferation	cytoplasm|intermediate filament	intermediate filament binding|structural molecule activity			ovary(6)	6	all_hematologic(923;0.088)|Hepatocellular(266;0.158)					CCCCAGCCCTCCCACCCCCTG	0.657													12	62					1.5842e-08	1.86096e-08	1	0
DARC	2532	broad.mit.edu	37	1	159176142	159176142	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:159176142G>A	uc001fto.2	+	2	1153	c.913G>A	c.(913-915)GCC>ACC	p.A305T	DARC_uc001ftp.3_Missense_Mutation_p.A307T	NM_002036	NP_002027	Q16570	DUFFY_HUMAN	Duffy blood group antigen isoform b	305	Helical; Name=7; (Potential).				defense response	integral to membrane|plasma membrane	C-C chemokine binding|chemokine receptor activity			ovary(1)|lung(1)	2	all_hematologic(112;0.0429)					CCTGCTCCTCGCCCTATTCTG	0.592													97	539					0	0	0	0
TOR3A	64222	broad.mit.edu	37	1	179064256	179064256	+	Missense_Mutation	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:179064256T>C	uc001gmd.2	+	6	1249	c.1097T>C	c.(1096-1098)ATA>ACA	p.I366T	TOR3A_uc010pnd.1_Missense_Mutation_p.I150T	NM_022371	NP_071766	Q9H497	TOR3A_HUMAN	torsin family 3, member A precursor	366					chaperone mediated protein folding requiring cofactor	endoplasmic reticulum	ATP binding			pancreas(1)	1						CTGGATGAAATAGCCCAGATG	0.507													27	311					0	0	0	0
KIF14	9928	broad.mit.edu	37	1	200529861	200529861	+	Missense_Mutation	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:200529861C>A	uc010ppk.1	-	26	4658	c.4219G>T	c.(4219-4221)GCC>TCC	p.A1407S	KIF14_uc010ppj.1_Missense_Mutation_p.A916S	NM_014875	NP_055690	Q15058	KIF14_HUMAN	kinesin family member 14	1407	Required for CIT-binding.				microtubule-based movement	cytoplasm|microtubule|nucleus|spindle	ATP binding|microtubule motor activity|protein binding			breast(3)|ovary(2)|skin(2)	7						TGGACACTGGCAGCTTTATTG	0.383													23	188					3.83957e-06	4.353e-06	1	0
CAMK1G	57172	broad.mit.edu	37	1	209786185	209786185	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:209786185C>T	uc001hhd.2	+	12	1498	c.1396C>T	c.(1396-1398)CGG>TGG	p.R466W	CAMK1G_uc001hhe.2_Missense_Mutation_p.R466W	NM_020439	NP_065172	Q96NX5	KCC1G_HUMAN	calcium/calmodulin-dependent protein kinase IG	466						Golgi membrane|plasma membrane	ATP binding|calmodulin binding|calmodulin-dependent protein kinase activity			breast(1)	1				OV - Ovarian serous cystadenocarcinoma(81;0.0475)		CTCCCACTGCCGGGCAGGGCA	0.502													8	121					0	0	0	0
AHCTF1	25909	broad.mit.edu	37	1	247059207	247059207	+	Missense_Mutation	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:247059207T>C	uc001ibu.1	-	12	1651	c.1644A>G	c.(1642-1644)ATA>ATG	p.I548M	AHCTF1_uc001ibv.1_Missense_Mutation_p.I557M|AHCTF1_uc009xgs.1_Translation_Start_Site	NM_015446	NP_056261	Q8WYP5	ELYS_HUMAN	transcription factor ELYS	548	Necessary for cytoplasmic localization (By similarity).				cytokinesis|mitotic prometaphase|mRNA transport|nuclear pore complex assembly|protein transport|transmembrane transport	condensed chromosome kinetochore|cytosol|nuclear matrix|nuclear membrane|nuclear pore|nucleoplasm	DNA binding			ovary(5)|skin(2)	7	all_cancers(71;3.05e-05)|all_epithelial(71;6.72e-06)|Ovarian(71;0.0173)|Breast(184;0.0318)|all_lung(81;0.0458)|Lung NSC(105;0.0518)	all_cancers(173;0.0266)	OV - Ovarian serous cystadenocarcinoma(106;0.00271)			CTGCTGACAATATAGCTTCTA	0.368													17	200					0	0	0	0
OR2T33	391195	broad.mit.edu	37	1	248436962	248436962	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:248436962C>T	uc010pzi.1	-	1	155	c.155G>A	c.(154-156)CGG>CAG	p.R52Q		NM_001004695	NP_001004695	Q8NG76	O2T33_HUMAN	olfactory receptor, family 2, subfamily T,	52	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			large_intestine(1)|ovary(1)	2	all_cancers(71;0.000124)|all_epithelial(71;1.03e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0245)			CGTGTGGAGCCGGTGGTCCCA	0.527													33	200					0	0	0	0
OR2M7	391196	broad.mit.edu	37	1	248486986	248486986	+	Missense_Mutation	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:248486986C>A	uc010pzk.1	-	1	885	c.885G>T	c.(883-885)AAG>AAT	p.K295N		NM_001004691	NP_001004691	Q8NG81	OR2M7_HUMAN	olfactory receptor, family 2, subfamily M,	295	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			skin(2)	2	all_cancers(71;0.000108)|all_epithelial(71;1.03e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0265)			TGGTCACTTCCTTGTTGCGGA	0.423													13	108					1.05317e-09	1.25225e-09	1	0
ANXA2P3	305	broad.mit.edu	37	10	66586101	66586101	+	RNA	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr10:66586101C>T	uc009xpm.1	+	1		c.817C>T				NR_001446				Human lipocortin (LIP) 2 pseudogene mRNA, complete cds-like region.												0						TGAACCTGGTCCAGTGCATTC	0.473													4	31					0	0	0	0
COL13A1	1305	broad.mit.edu	37	10	71707080	71707080	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr10:71707080C>T	uc001jpr.1	+	36	2543	c.2007C>T	c.(2005-2007)CCC>CCT	p.P669P	COL13A1_uc001jqj.1_Silent_p.P642P|COL13A1_uc001jps.1_Silent_p.P640P|COL13A1_uc001jpt.1_Silent_p.P628P|COL13A1_uc001jpu.1_Silent_p.P638P|COL13A1_uc001jpv.1_Silent_p.P643P|COL13A1_uc001jpx.1_Silent_p.P620P|COL13A1_uc001jpw.1_Silent_p.P616P|COL13A1_uc001jpy.1_Silent_p.P607P|COL13A1_uc001jpz.1_Silent_p.P612P|COL13A1_uc001jqa.1_Silent_p.P609P|COL13A1_uc001jqc.1_Silent_p.P654P|COL13A1_uc001jqb.1_Silent_p.P591P|COL13A1_uc001jql.2_Silent_p.P669P|COL13A1_uc001jqd.1_Silent_p.P657P|COL13A1_uc001jqe.1_Silent_p.P652P|COL13A1_uc001jqf.1_Silent_p.P650P|COL13A1_uc001jqg.1_Silent_p.P647P|COL13A1_uc001jqh.1_Silent_p.P657P|COL13A1_uc001jqi.1_Silent_p.P655P|COL13A1_uc010qjf.1_Silent_p.P444P	NM_005203	NP_005194	Q5TAT6	CODA1_HUMAN	alpha 1 type XIII collagen isoform 1	669	Extracellular (Potential).|Triple-helical region 3 (COL3).				cell differentiation|cell-cell adhesion|cell-matrix adhesion|endochondral ossification|morphogenesis of a branching structure	collagen type XIII|integral to membrane	extracellular matrix structural constituent|heparin binding|protein binding			ovary(1)	1					Atorvastatin(DB01076)|Simvastatin(DB00641)	ATGGACCACCCGGGGACAAGG	0.517													4	80					0	0	0	0
KIF20B	9585	broad.mit.edu	37	10	91476203	91476203	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr10:91476203G>C	uc001kgs.1	+	9	1023	c.951G>C	c.(949-951)TGG>TGC	p.W317C	KIF20B_uc001kgr.1_Missense_Mutation_p.W317C	NM_016195	NP_057279	Q96Q89	KI20B_HUMAN	M-phase phosphoprotein 1	317	Kinesin-motor.				cell cycle arrest|cell division|microtubule-based movement|mitosis|regulation of mitosis	centrosome|microtubule|nucleolus|nucleoplasm|spindle	ATP binding|ATPase activity|microtubule motor activity|WW domain binding			ovary(1)|pancreas(1)|skin(1)	3						ATCTACAATGGATTCAAGTAT	0.303													5	46					0	0	0	0
CYP26C1	340665	broad.mit.edu	37	10	94824176	94824176	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr10:94824176G>A	uc010qns.1	+	4	744	c.744G>A	c.(742-744)GAG>GAA	p.E248E	CYP26C1_uc009xud.2_Intron	NM_183374	NP_899230	Q6V0L0	CP26C_HUMAN	cytochrome P450, family 26, subfamily C,	248					anterior/posterior pattern formation|central nervous system development|negative regulation of retinoic acid receptor signaling pathway|neural crest cell development|organelle fusion|retinoic acid catabolic process|xenobiotic metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	electron carrier activity|heme binding|retinoic acid 4-hydroxylase activity|retinoic acid binding			central_nervous_system(1)	1		Colorectal(252;0.122)				GGCACCTGGAGGGGGCCATTT	0.612													3	66					0	0	0	0
PDZD7	79955	broad.mit.edu	37	10	102781636	102781636	+	Silent	SNP	G	A	A	rs148746572		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr10:102781636G>A	uc001kso.1	-	6	1001	c.786C>T	c.(784-786)AAC>AAT	p.N262N	PDZD7_uc001ksn.2_Silent_p.N262N	NM_024895	NP_079171	Q9H5P4	PDZD7_HUMAN	PDZ domain containing 7	262	PDZ 2.					cilium|nucleus	protein binding			ovary(1)|breast(1)|central_nervous_system(1)	3				Epithelial(162;6.98e-09)|all cancers(201;3.55e-07)		ACCTGACACCGTTGGCTGCCA	0.622													24	160					0	0	0	0
HTRA1	5654	broad.mit.edu	37	10	124266371	124266371	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr10:124266371G>A	uc001lgj.2	+	4	1070	c.942G>A	c.(940-942)ATG>ATA	p.M314I		NM_002775	NP_002766	Q92743	HTRA1_HUMAN	HtrA serine peptidase 1 precursor	314	Serine protease.				proteolysis|regulation of cell growth	extracellular space	insulin-like growth factor binding|serine-type endopeptidase activity				0		all_neural(114;0.0765)|Lung NSC(174;0.133)|all_lung(145;0.163)|Breast(234;0.238)				ACTCAGACATGGACTACATCC	0.602													15	78					0	0	0	0
OR5P2	120065	broad.mit.edu	37	11	7817810	7817810	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:7817810G>T	uc001mfp.1	-	1	680	c.680C>A	c.(679-681)ACT>AAT	p.T227N		NM_153444	NP_703145	Q8WZ92	OR5P2_HUMAN	olfactory receptor, family 5, subfamily P,	227	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)|skin(2)|central_nervous_system(1)	5				Epithelial(150;8.62e-08)|BRCA - Breast invasive adenocarcinoma(625;0.189)		GTGCCCCTCAGTGGAGCGCAT	0.483													7	122					0.00198382	0.00213726	1	0
SPON1	10418	broad.mit.edu	37	11	14282159	14282159	+	Silent	SNP	A	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:14282159A>T	uc001mle.2	+	15	2395	c.1857A>T	c.(1855-1857)CCA>CCT	p.P619P		NM_006108	NP_006099	Q9HCB6	SPON1_HUMAN	spondin 1, extracellular matrix protein	619	TSP type-1 4.				cell adhesion	extracellular space|proteinaceous extracellular matrix	protein binding				0				Epithelial(150;0.00898)		TGCTGTCCCCATGGTCCGAGT	0.547													10	85					0	0	0	0
CELF1	10658	broad.mit.edu	37	11	47508744	47508744	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:47508744C>G	uc001nfl.2	-	2	238	c.228G>C	c.(226-228)CAG>CAC	p.Q76H	CELF1_uc001nfm.2_Missense_Mutation_p.Q76H|CELF1_uc001nfn.2_Missense_Mutation_p.Q76H|CELF1_uc001nfo.1_Missense_Mutation_p.Q103H|CELF1_uc010rhm.1_Missense_Mutation_p.Q76H|CELF1_uc001nfp.2_Missense_Mutation_p.Q103H|CELF1_uc001nfq.1_Missense_Mutation_p.Q76H|CELF1_uc001nfr.1_Missense_Mutation_p.Q76H	NM_001025596	NP_001020767	Q92879	CELF1_HUMAN	CUG triplet repeat, RNA-binding protein 1	76	RRM 1.				embryo development|mRNA splice site selection|regulation of RNA splicing|RNA interference	cytoplasm|nucleus|ribonucleoprotein complex	BRE binding|mRNA binding|nucleotide binding|translation repressor activity, nucleic acid binding			central_nervous_system(2)|ovary(1)	3						GAAGAGCATTCTGAGCTTCTA	0.373													4	187					0	0	0	0
OR5R1	219479	broad.mit.edu	37	11	56185534	56185534	+	Missense_Mutation	SNP	T	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:56185534T>A	uc010rji.1	-	1	175	c.175A>T	c.(175-177)ATG>TTG	p.M59L		NM_001004744	NP_001004744	Q8NH85	OR5R1_HUMAN	olfactory receptor, family 5, subfamily R,	59	Helical; Name=2; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)	2	Esophageal squamous(21;0.00448)					AAATAGTACATAGGTGTGTGG	0.438													10	73					0	0	0	0
SSRP1	6749	broad.mit.edu	37	11	57094220	57094220	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:57094220G>A	uc001njt.2	-	16	2282	c.2015C>T	c.(2014-2016)TCT>TTT	p.S672F	TNKS1BP1_uc001njs.2_5'Flank|TNKS1BP1_uc009ymd.1_5'Flank	NM_003146	NP_003137	Q08945	SSRP1_HUMAN	structure specific recognition protein 1	672	Ser-rich.				DNA repair|DNA replication|positive regulation of viral transcription|regulation of transcription, DNA-dependent|transcription elongation from RNA polymerase II promoter|viral reproduction	chromosome|cytoplasm|nucleoplasm	DNA binding|protein binding			ovary(2)	2						CTCTCCCGAAGAGCTCTCATC	0.552													6	146					0	0	0	0
CTNND1	1500	broad.mit.edu	37	11	57569359	57569359	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:57569359G>T	uc001nmc.3	+	7	1682	c.1111G>T	c.(1111-1113)GTG>TTG	p.V371L	CTNND1_uc001nlh.1_Missense_Mutation_p.V371L|CTNND1_uc001nlu.3_Missense_Mutation_p.V270L|CTNND1_uc001nlt.3_Missense_Mutation_p.V270L|CTNND1_uc001nls.3_Missense_Mutation_p.V270L|CTNND1_uc001nlw.3_Missense_Mutation_p.V270L|CTNND1_uc001nmf.3_Missense_Mutation_p.V371L|CTNND1_uc001nmd.3_Missense_Mutation_p.V317L|CTNND1_uc001nlk.3_Missense_Mutation_p.V317L|CTNND1_uc001nme.3_Missense_Mutation_p.V371L|CTNND1_uc001nll.3_Missense_Mutation_p.V317L|CTNND1_uc001nmg.3_Missense_Mutation_p.V317L|CTNND1_uc001nlj.3_Missense_Mutation_p.V317L|CTNND1_uc001nlr.3_Missense_Mutation_p.V317L|CTNND1_uc001nlp.3_Missense_Mutation_p.V317L|CTNND1_uc001nlx.3_Missense_Mutation_p.V48L|CTNND1_uc001nlz.3_Missense_Mutation_p.V48L|CTNND1_uc009ymn.2_Missense_Mutation_p.V48L|CTNND1_uc001nlm.3_Missense_Mutation_p.V371L|CTNND1_uc001nly.3_Missense_Mutation_p.V48L|CTNND1_uc001nmb.3_Missense_Mutation_p.V48L|CTNND1_uc001nma.3_Missense_Mutation_p.V48L|CTNND1_uc001nmi.3_Missense_Mutation_p.V270L|CTNND1_uc001nmh.3_Missense_Mutation_p.V371L|CTNND1_uc001nlq.3_Missense_Mutation_p.V270L|CTNND1_uc001nln.3_Missense_Mutation_p.V371L|CTNND1_uc001nli.3_Missense_Mutation_p.V371L|CTNND1_uc001nlo.3_Missense_Mutation_p.V270L|CTNND1_uc001nlv.3_Missense_Mutation_p.V270L	NM_001085458	NP_001078927	O60716	CTND1_HUMAN	catenin, delta 1 isoform 1ABC	371	ARM 1.				adherens junction organization|cell junction assembly|negative regulation of canonical Wnt receptor signaling pathway|regulation of transcription, DNA-dependent|transcription, DNA-dependent|Wnt receptor signaling pathway	cytosol|midbody|nucleus	cadherin binding|protein binding|receptor binding			breast(4)|ovary(1)|kidney(1)	6		all_epithelial(135;0.155)				GCTGCCAGAGGTGATCGCCAT	0.537													6	104					0.000157383	0.000173388	1	0
INTS5	80789	broad.mit.edu	37	11	62416747	62416747	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:62416747G>C	uc001nud.2	-	2	858	c.805C>G	c.(805-807)CAG>GAG	p.Q269E	GANAB_uc001nua.2_5'Flank|GANAB_uc001nub.2_5'Flank|GANAB_uc001nuc.2_5'Flank|GANAB_uc010rma.1_5'Flank|GANAB_uc010rmb.1_5'Flank	NM_030628	NP_085131	Q6P9B9	INT5_HUMAN	integrator complex subunit 5	269					snRNA processing	integral to membrane|integrator complex	protein binding			ovary(2)	2						GAGGGGGTCTGAGAAGAGCTT	0.577													4	70					0	0	0	0
MALAT1	378938	broad.mit.edu	37	11	65266792	65266792	+	RNA	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:65266792C>A	uc010roh.1	+	1		c.1560C>A			MALAT1_uc001odz.2_5'Flank	NR_002819				Homo sapiens clone alpha1 mRNA sequence.												0						GATGAAGCTTCTTCATGGAGT	0.328													4	12					0.00909568	0.00969212	1	0
LOC645332	645332	broad.mit.edu	37	11	67564228	67564228	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:67564228C>T	uc001omt.3	-	3	259	c.236G>A	c.(235-237)AGC>AAC	p.S79N	LOC645332_uc001omu.3_Intron	NR_024249				SubName: Full=cDNA FLJ57700, weakly similar to Protein FAM86A;												0						GAGGAGCCCGCTGGTGCTCCC	0.627													4	66					0	0	0	0
CCND1	595	broad.mit.edu	37	11	69457891	69457891	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:69457891C>T	uc001opa.2	+	2	500	c.291C>T	c.(289-291)AGC>AGT	p.S97S		NM_053056	NP_444284	P24385	CCND1_HUMAN	cyclin D1	97	Cyclin N-terminal.				cell division|G1 phase of mitotic cell cycle|G1/S transition of mitotic cell cycle|mitotic cell cycle G1/S transition DNA damage checkpoint|positive regulation of cyclin-dependent protein kinase activity|positive regulation of protein phosphorylation|response to drug|response to UV-A|S phase of mitotic cell cycle	cyclin-dependent protein kinase holoenzyme complex|cytosol|membrane|nucleoplasm	protein kinase binding			ovary(1)|lung(1)	2	all_cancers(3;2.01e-114)|all_epithelial(3;3.59e-122)|Breast(3;5.4e-34)|all_lung(4;1.99e-21)|Lung NSC(4;4.65e-21)|Hepatocellular(3;8.22e-16)|Melanoma(5;1.89e-05)|Ovarian(3;0.0348)		Epithelial(3;7.2e-57)|all cancers(3;7.75e-51)|BRCA - Breast invasive adenocarcinoma(2;4.9e-48)|Lung(3;1.13e-16)|LUSC - Lung squamous cell carcinoma(11;3.74e-15)|STAD - Stomach adenocarcinoma(18;0.0278)|LUAD - Lung adenocarcinoma(13;0.0537)		Arsenic trioxide(DB01169)	TGAAAAAGAGCCGCCTGCAGC	0.602			T	IGH@|FSTL3	CLL|B-ALL|breast					Multiple Myeloma(6;0.086)			4	101					0	0	0	0
ORAOV1	220064	broad.mit.edu	37	11	69482751	69482751	+	Missense_Mutation	SNP	A	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:69482751A>G	uc001opc.2	-	4	415	c.257T>C	c.(256-258)ATT>ACT	p.I86T	ORAOV1_uc010rqi.1_Missense_Mutation_p.I86T|ORAOV1_uc009ysm.2_RNA|ORAOV1_uc001opd.2_Missense_Mutation_p.I27T	NM_153451	NP_703152	Q8WV07	ORAV1_HUMAN	oral cancer overexpressed 1	86											0	all_cancers(3;5.53e-114)|all_epithelial(3;1.34e-121)|Breast(3;9.28e-34)|all_lung(4;1.99e-21)|Lung NSC(4;4.65e-21)|Hepatocellular(3;6.15e-15)|Melanoma(5;1.89e-05)|Ovarian(3;0.0348)		Epithelial(3;5.64e-57)|all cancers(3;5.98e-51)|BRCA - Breast invasive adenocarcinoma(2;5.49e-48)|Lung(3;1.13e-16)|LUSC - Lung squamous cell carcinoma(11;3.74e-15)|STAD - Stomach adenocarcinoma(18;0.0278)|LUAD - Lung adenocarcinoma(13;0.0537)			GATCATTCCAATCAATGATTC	0.403													9	699					0	0	0	0
TAGLN	6876	broad.mit.edu	37	11	117075006	117075006	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:117075006G>A	uc001pqm.2	+	5	658	c.537G>A	c.(535-537)ATG>ATA	p.M179I	uc001pqk.1_5'Flank|TAGLN_uc001pql.1_Intron|TAGLN_uc001pqn.2_Missense_Mutation_p.M179I|TAGLN_uc001pqo.2_Missense_Mutation_p.M179I|TAGLN_uc001pqp.2_Missense_Mutation_p.M179I|uc001pqq.1_5'Flank	NM_003186	NP_003177	Q01995	TAGL_HUMAN	transgelin	179	Calponin-like.			M -> V (in Ref. 2; AAA58375).	muscle organ development	cytoplasm	actin binding				0	all_hematologic(175;0.0487)	Breast(348;0.00908)|Medulloblastoma(222;0.0425)|all_hematologic(192;0.196)|all_neural(223;0.234)		BRCA - Breast invasive adenocarcinoma(274;1.63e-06)|Epithelial(105;5.49e-05)|all cancers(92;0.000435)		GCCTTCAGATGGGCAGCAACA	0.587													3	99					0	0	0	0
HYOU1	10525	broad.mit.edu	37	11	118921809	118921809	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:118921809C>T	uc001puu.2	-	14	1796	c.1603G>A	c.(1603-1605)GAG>AAG	p.E535K	HYOU1_uc001put.2_Missense_Mutation_p.E500K|HYOU1_uc010ryu.1_Missense_Mutation_p.E555K|HYOU1_uc010ryv.1_Missense_Mutation_p.E424K|HYOU1_uc001pux.3_Missense_Mutation_p.E535K|HYOU1_uc010ryw.1_RNA|HYOU1_uc001puw.1_Missense_Mutation_p.E535K	NM_006389	NP_006380	Q9Y4L1	HYOU1_HUMAN	hypoxia up-regulated 1 precursor	535						endoplasmic reticulum lumen	ATP binding|protein binding				0	all_hematologic(175;0.0839)	Medulloblastoma(222;0.0425)|Breast(348;0.052)|all_neural(223;0.112)|all_hematologic(192;0.207)		BRCA - Breast invasive adenocarcinoma(274;7.78e-05)		CCCTTGGACTCGTAGTCAGGA	0.527													6	81					0	0	0	0
Unknown	0	broad.mit.edu	37	11	124120818	124120818	+	IGR	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:124120818C>A								OR8G2 (24508 upstream) : OR8D1 (58919 downstream)																							CCTTGCTGTACAGTGTCATCA	0.448													14	164					3.27435e-08	3.7781e-08	1	0
CD163	9332	broad.mit.edu	37	12	7637727	7637727	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:7637727G>C	uc001qsz.3	-	11	2872	c.2744C>G	c.(2743-2745)GCC>GGC	p.A915G	CD163_uc001qta.3_Missense_Mutation_p.A915G|CD163_uc009zfw.2_Missense_Mutation_p.A948G	NM_004244	NP_004235	Q86VB7	C163A_HUMAN	CD163 antigen isoform a	915	SRCR 8.|Extracellular (Potential).				acute-phase response	extracellular region|integral to plasma membrane	protein binding|scavenger receptor activity			ovary(6)|pancreas(1)|skin(1)	8						CGAGGGGCTGGCCAGTCTCTT	0.517													18	214					0	0	0	0
EPS8	2059	broad.mit.edu	37	12	15776179	15776179	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:15776179G>T	uc009zif.2	-	20	2362	c.2268C>A	c.(2266-2268)TTC>TTA	p.F756L	EPS8_uc001rdb.2_Missense_Mutation_p.F756L|EPS8_uc009zig.2_Missense_Mutation_p.F496L|EPS8_uc010shv.1_Missense_Mutation_p.F496L	NM_004447	NP_004438	Q12929	EPS8_HUMAN	epidermal growth factor receptor pathway	756					cell proliferation|epidermal growth factor receptor signaling pathway		SH3/SH2 adaptor activity			ovary(2)|upper_aerodigestive_tract(1)|skin(1)	4		all_epithelial(100;1.87e-05)|Breast(259;0.000286)|Hepatocellular(102;0.244)		BRCA - Breast invasive adenocarcinoma(232;4.29e-05)|GBM - Glioblastoma multiforme(207;0.0264)		TATTGAGAGAGAAAAGTTGTG	0.378													19	120					1.67942e-08	1.96099e-08	1	0
OR6C70	390327	broad.mit.edu	37	12	55863666	55863666	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:55863666C>T	uc010spn.1	-	1	257	c.257G>A	c.(256-258)AGG>AAG	p.R86K		NM_001005499	NP_001005499	A6NIJ9	O6C70_HUMAN	olfactory receptor, family 6, subfamily C,	86	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			skin(1)	1						GGTCTTTTCCCTGGTAACAAT	0.378													18	131					0	0	0	0
DNAJC14	85406	broad.mit.edu	37	12	56221277	56221277	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:56221277C>T	uc001shx.1	-	2	1370	c.1166G>A	c.(1165-1167)CGG>CAG	p.R389Q	DNAJC14_uc001shu.1_Missense_Mutation_p.R389Q|DNAJC14_uc009zob.1_Missense_Mutation_p.R389Q|DNAJC14_uc001shy.1_Missense_Mutation_p.R389Q	NM_032364	NP_115740	Q6Y2X3	DJC14_HUMAN	dopamine receptor interacting protein	389					protein folding|protein transport	endoplasmic reticulum membrane|integral to membrane	heat shock protein binding|unfolded protein binding			ovary(3)|large_intestine(1)	4						TCTTACCAGCCGCTGCCATGG	0.547													7	157					0	0	0	0
TIMELESS	8914	broad.mit.edu	37	12	56814387	56814387	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:56814387C>T	uc001slf.2	-	26	3362	c.3194G>A	c.(3193-3195)CGC>CAC	p.R1065H		NM_003920	NP_003911	Q9UNS1	TIM_HUMAN	timeless homolog	1065					cell division|circadian rhythm|detection of abiotic stimulus|mitosis|morphogenesis of an epithelium|negative regulation of transcription, DNA-dependent|regulation of S phase|response to DNA damage stimulus|transcription, DNA-dependent	nuclear chromatin				ovary(5)|breast(2)|pancreas(1)	8						CCCTAGCTTGCGCAACAGCTG	0.428													11	148					0	0	0	0
TIMELESS	8914	broad.mit.edu	37	12	56814831	56814831	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:56814831C>T	uc001slf.2	-	24	3124	c.2956G>A	c.(2956-2958)GAA>AAA	p.E986K		NM_003920	NP_003911	Q9UNS1	TIM_HUMAN	timeless homolog	986					cell division|circadian rhythm|detection of abiotic stimulus|mitosis|morphogenesis of an epithelium|negative regulation of transcription, DNA-dependent|regulation of S phase|response to DNA damage stimulus|transcription, DNA-dependent	nuclear chromatin				ovary(5)|breast(2)|pancreas(1)	8						CCCCCTTCTTCTTCCTCTTCG	0.478													13	236					0	0	0	0
TIMELESS	8914	broad.mit.edu	37	12	56815188	56815188	+	Nonsense_Mutation	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:56815188C>A	uc001slf.2	-	23	2983	c.2815G>T	c.(2815-2817)GAG>TAG	p.E939*		NM_003920	NP_003911	Q9UNS1	TIM_HUMAN	timeless homolog	939					cell division|circadian rhythm|detection of abiotic stimulus|mitosis|morphogenesis of an epithelium|negative regulation of transcription, DNA-dependent|regulation of S phase|response to DNA damage stimulus|transcription, DNA-dependent	nuclear chromatin				ovary(5)|breast(2)|pancreas(1)	8						TCCCGCCGCTCAGCCACCAGC	0.512													11	205					4.3838e-07	5.02848e-07	1	0
PIP4K2C	79837	broad.mit.edu	37	12	57992919	57992919	+	Silent	SNP	C	T	T	rs147041101		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:57992919C>T	uc001sou.2	+	5	716	c.585C>T	c.(583-585)AAC>AAT	p.N195N	PIP4K2C_uc001sot.2_Silent_p.N195N|PIP4K2C_uc010srs.1_Silent_p.N177N|PIP4K2C_uc010srt.1_Silent_p.N147N	NM_001146258	NP_001139730	Q8TBX8	PI42C_HUMAN	phosphatidylinositol-5-phosphate 4-kinase, type	195	PIPK.					cytoplasm|membrane	1-phosphatidylinositol-5-phosphate 4-kinase activity|ATP binding|identical protein binding			central_nervous_system(2)|lung(1)	3	Melanoma(17;0.122)					GTGTGGACAACGAAGACAGCT	0.512													14	138					0	0	0	0
TMTC2	160335	broad.mit.edu	37	12	83251023	83251023	+	Silent	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:83251023C>A	uc001szt.2	+	2	750	c.318C>A	c.(316-318)TCC>TCA	p.S106S	TMTC2_uc001szr.1_Silent_p.S106S|TMTC2_uc001szs.1_Silent_p.S106S|TMTC2_uc010suk.1_Intron	NM_152588	NP_689801	Q8N394	TMTC2_HUMAN	transmembrane and tetratricopeptide repeat	106						endoplasmic reticulum|integral to membrane	binding			ovary(2)	2						CAAGCTTCTCCAAGATCCTCC	0.522													16	141					2.62699e-14	3.20164e-14	1	0
GCN1L1	10985	broad.mit.edu	37	12	120597955	120597955	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:120597955C>T	uc001txo.2	-	23	2554	c.2541G>A	c.(2539-2541)CGG>CGA	p.R847R		NM_006836	NP_006827	Q92616	GCN1L_HUMAN	GCN1 general control of amino-acid synthesis	847					regulation of translation	ribosome	protein binding|translation factor activity, nucleic acid binding			ovary(4)	4	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)					CCTCCTGCAGCCGCCTCCGGA	0.612													4	86					0	0	0	0
SETDB2	83852	broad.mit.edu	37	13	50054403	50054403	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr13:50054403C>T	uc001vcz.2	+	8	1860	c.954C>T	c.(952-954)TCC>TCT	p.S318S	SETDB2_uc010adg.2_Silent_p.S294S|SETDB2_uc001vcy.3_Silent_p.S306S|SETDB2_uc010adh.2_Silent_p.S306S|SETDB2_uc001vda.2_Silent_p.S306S	NM_031915	NP_114121	Q96T68	SETB2_HUMAN	SET domain, bifurcated 2 isoform a	318	Pre-SET.				cell division|chromosome segregation|heart looping|left/right axis specification|mitosis|negative regulation of transcription, DNA-dependent	chromosome|nucleus	DNA binding|histone methyltransferase activity (H3-K9 specific)|zinc ion binding			ovary(1)|central_nervous_system(1)	2		Lung NSC(96;0.000408)|Breast(56;0.00131)|Prostate(109;0.00446)|Hepatocellular(98;0.0556)|Glioma(44;0.236)	KIRC - Kidney renal clear cell carcinoma(9;0.206)	GBM - Glioblastoma multiforme(99;3.1e-09)		CCAAAACTTCCCCCTTGTCAA	0.408													23	270					0	0	0	0
ATP4B	496	broad.mit.edu	37	13	114307336	114307336	+	Missense_Mutation	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr13:114307336T>C	uc001vtz.2	-	4	449	c.407A>G	c.(406-408)TAC>TGC	p.Y136C	ATP4B_uc010agy.1_Missense_Mutation_p.Y136C	NM_000705	NP_000696	P51164	ATP4B_HUMAN	hydrogen/potassium-exchanging ATPase 4B	136	Extracellular (Potential).				ATP biosynthetic process	integral to membrane|plasma membrane	hydrogen:potassium-exchanging ATPase activity|sodium:potassium-exchanging ATPase activity			ovary(1)	1	Lung NSC(43;0.0113)|all_neural(89;0.0337)|Hepatocellular(20;0.0877)|Medulloblastoma(90;0.163)|Lung SC(71;0.218)	all_cancers(25;0.00696)|all_epithelial(44;0.00347)|all_lung(25;0.0221)|Breast(118;0.0411)|Lung NSC(25;0.0839)	all cancers(43;0.171)		Rabeprazole(DB01129)	CTGGAAGAAGTACTGCTCGGA	0.617													5	96					0	0	0	0
C14orf118	55668	broad.mit.edu	37	14	76644359	76644359	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr14:76644359C>G	uc001xsh.2	+	7	1167	c.1081C>G	c.(1081-1083)CCT>GCT	p.P361A	C14orf118_uc001xsi.2_Intron|C14orf118_uc001xsl.2_Intron	NM_017926	NP_060396	Q9NWQ4	CN118_HUMAN	hypothetical protein LOC55668 isoform 1	361										ovary(2)|skin(1)	3				BRCA - Breast invasive adenocarcinoma(234;0.0172)		TTCTGATTTTCCTCACATTTC	0.338													3	125					0	0	0	0
ANGEL1	23357	broad.mit.edu	37	14	77269772	77269772	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr14:77269772G>A	uc001xsv.2	-	7	1673	c.1560C>T	c.(1558-1560)ATC>ATT	p.I520I	ANGEL1_uc010tvf.1_Intron	NM_015305	NP_056120	Q9UNK9	ANGE1_HUMAN	angel homolog 1	520										ovary(2)|central_nervous_system(1)|skin(1)	4			Kidney(204;0.164)	BRCA - Breast invasive adenocarcinoma(234;0.0285)		GCTGACAAGCGATGCTGCAGA	0.473													5	91					0	0	0	0
TMEM63C	57156	broad.mit.edu	37	14	77685844	77685844	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr14:77685844G>A	uc001xtf.2	+	4	366	c.154G>A	c.(154-156)GTC>ATC	p.V52I	TMEM63C_uc010asq.1_Missense_Mutation_p.V52I	NM_020431	NP_065164	Q9P1W3	TM63C_HUMAN	transmembrane protein 63C	52	Helical; (Potential).					integral to membrane					0			Kidney(204;0.164)	BRCA - Breast invasive adenocarcinoma(234;0.0342)		CCTGTAGCTCGTCCTTGTGGT	0.592													17	155					0	0	0	0
AVEN	57099	broad.mit.edu	37	15	34163164	34163164	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr15:34163164C>T	uc001zhj.2	-	4	640	c.584G>A	c.(583-585)CGA>CAA	p.R195Q		NM_020371	NP_065104	Q9NQS1	AVEN_HUMAN	cell death regulator aven	195					anti-apoptosis|apoptosis	endomembrane system|intracellular|membrane|membrane fraction	protein binding			kidney(1)	1		all_lung(180;1.78e-08)		all cancers(64;1.66e-15)|GBM - Glioblastoma multiforme(113;1.42e-05)|BRCA - Breast invasive adenocarcinoma(123;0.0359)		AACGTTGAGTCGGAGGCAGAG	0.438													5	46					0	0	0	0
HERC1	8925	broad.mit.edu	37	15	64067311	64067311	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr15:64067311G>A	uc002amp.2	-	2	660	c.512C>T	c.(511-513)GCG>GTG	p.A171V	HERC1_uc010uil.1_Missense_Mutation_p.A171V|HERC1_uc010bgt.1_Missense_Mutation_p.A171V|HERC1_uc002amq.1_Missense_Mutation_p.A171V	NM_003922	NP_003913	Q15751	HERC1_HUMAN	hect domain and RCC1-like domain 1	171					protein modification process|transport	cytosol|Golgi apparatus|membrane	acid-amino acid ligase activity|ARF guanyl-nucleotide exchange factor activity			ovary(6)|breast(6)|lung(5)|central_nervous_system(2)	19						TCTTAGAAGCGCAAATAATAA	0.448													5	387					0	0	0	0
ISLR2	57611	broad.mit.edu	37	15	74427051	74427051	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr15:74427051C>T	uc002axd.2	+	4	2725	c.1956C>T	c.(1954-1956)CTC>CTT	p.L652L	ISLR2_uc002axe.2_Silent_p.L652L|ISLR2_uc010bjg.2_Silent_p.L652L|ISLR2_uc010bjf.2_Silent_p.L652L	NM_001130136	NP_001123608	Q6UXK2	ISLR2_HUMAN	immunoglobulin superfamily containing	652	Cytoplasmic (Potential).				positive regulation of axon extension	cell surface|integral to membrane|plasma membrane					0						CTTCGTACCTCGAGTCCGAGA	0.677											OREG0023277	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	8	101					0	0	0	0
PTPN9	5780	broad.mit.edu	37	15	75815511	75815511	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr15:75815511G>C	uc002bal.2	-	4	881	c.373C>G	c.(373-375)CAT>GAT	p.H125D		NM_002833	NP_002824	P43378	PTN9_HUMAN	protein tyrosine phosphatase, non-receptor type	125	CRAL-TRIO.					cytoplasmic part	non-membrane spanning protein tyrosine phosphatase activity|protein binding			lung(1)|skin(1)	2						AGTACCACATGTTGGACTGAC	0.428													5	62					0	0	0	0
AKAP13	11214	broad.mit.edu	37	15	86122930	86122930	+	Missense_Mutation	SNP	A	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr15:86122930A>T	uc002blv.1	+	7	1801	c.1631A>T	c.(1630-1632)GAT>GTT	p.D544V	AKAP13_uc002blt.1_Missense_Mutation_p.D544V|AKAP13_uc002blu.1_Missense_Mutation_p.D544V	NM_007200	NP_009131	Q12802	AKP13_HUMAN	A-kinase anchor protein 13 isoform 2	544					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|membrane|membrane fraction|nucleus	cAMP-dependent protein kinase activity|metal ion binding|protein binding|Rho guanyl-nucleotide exchange factor activity|signal transducer activity			central_nervous_system(3)|kidney(2)|urinary_tract(1)|liver(1)|skin(1)|ovary(1)	9						AGTTCCCTGGATGGTAACAAA	0.468													15	126					0	0	0	0
FANCI	55215	broad.mit.edu	37	15	89836226	89836226	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr15:89836226C>G	uc010bnp.1	+	22	2313	c.2223C>G	c.(2221-2223)ATC>ATG	p.I741M	FANCI_uc002bnm.1_Missense_Mutation_p.I741M|FANCI_uc002bnn.1_RNA|FANCI_uc002bnp.1_Missense_Mutation_p.I562M|FANCI_uc002bnq.1_Missense_Mutation_p.I154M	NM_001113378	NP_001106849	Q9NVI1	FANCI_HUMAN	Fanconi anemia, complementation group I isoform	741					cell cycle|DNA repair	nucleoplasm	protein binding			ovary(2)	2	Lung NSC(78;0.0472)|all_lung(78;0.089)					AAAATAATATCTGTGCTTTTC	0.313								Direct_reversal_of_damage|Involved_in_tolerance_or_repair_of_DNA_crosslinks	Fanconi_Anemia				15	139					0	0	0	0
C16orf91	283951	broad.mit.edu	37	16	1478469	1478469	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr16:1478469G>A	uc010uvd.1	-	2	182	c.182C>T	c.(181-183)GCG>GTG	p.A61V		NM_001010878	NP_001010878	Q4G0I0	CSMT1_HUMAN	hypothetical protein LOC283951	Error:Variant_position_missing_in_Q4G0I0_after_alignment						integral to membrane					0						GTCCACCTGCGCCCGAAGCCT	0.672													4	27					0	0	0	0
UMOD	7369	broad.mit.edu	37	16	20352551	20352551	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr16:20352551G>A	uc002dgz.2	-	7	1568	c.1439C>T	c.(1438-1440)TCC>TTC	p.S480F	UMOD_uc002dha.2_Missense_Mutation_p.S480F|UMOD_uc002dhb.2_Missense_Mutation_p.S513F	NM_003361	NP_003352	P07911	UROM_HUMAN	uromodulin precursor	480	ZP.				cellular defense response|negative regulation of cell proliferation	anchored to membrane|apical plasma membrane|basolateral plasma membrane|cilium membrane|extrinsic to membrane|primary cilium|spindle pole	calcium ion binding			ovary(1)|skin(1)	2						AGCCTCAGTGGACAGTGTCAC	0.587													7	65					0	0	0	0
ZNF771	51333	broad.mit.edu	37	16	30419501	30419501	+	Missense_Mutation	SNP	A	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr16:30419501A>G	uc002dyd.2	+	2	387	c.127A>G	c.(127-129)ATG>GTG	p.M43V	ZNF771_uc002dyc.2_RNA|ZNF771_uc010ver.1_Missense_Mutation_p.M43V|ZNF771_uc010bzx.2_RNA	NM_001142305	NP_001135777	Q7L3S4	ZN771_HUMAN	zinc finger protein 771	43					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0			Colorectal(24;0.193)			CAAGATCCCCATGGACAACAA	0.333													8	79					0	0	0	0
ELMO3	79767	broad.mit.edu	37	16	67234439	67234439	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr16:67234439C>T	uc002esa.2	+	6	701	c.658C>T	c.(658-660)CCC>TCC	p.P220S	ELMO3_uc002esb.2_Missense_Mutation_p.P203S|ELMO3_uc002esc.2_Missense_Mutation_p.P54S	NM_024712	NP_078988	Q96BJ8	ELMO3_HUMAN	engulfment and cell motility 3	167					apoptosis|phagocytosis	cytoplasm|cytoskeleton	SH3 domain binding				0		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.00067)|Epithelial(162;0.00442)|all cancers(182;0.0417)		TCTGAGCATCCCCTTTGTGAG	0.647													14	109					0	0	0	0
TSNAXIP1	55815	broad.mit.edu	37	16	67854801	67854801	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr16:67854801G>C	uc002euj.2	+	3	439	c.45G>C	c.(43-45)CAG>CAC	p.Q15H	TSNAXIP1_uc010cep.2_5'UTR|TSNAXIP1_uc010vjz.1_Intron|TSNAXIP1_uc002euf.3_Intron|TSNAXIP1_uc010vka.1_Missense_Mutation_p.Q69H|TSNAXIP1_uc010vkb.1_Intron|TSNAXIP1_uc002eug.3_Intron|TSNAXIP1_uc002euh.3_Intron|TSNAXIP1_uc002eui.3_Intron|TSNAXIP1_uc002euk.2_5'Flank	NM_018430	NP_060900	Q2TAA8	TXIP1_HUMAN	translin-associated factor X interacting protein	15					cell differentiation|multicellular organismal development|spermatogenesis	perinuclear region of cytoplasm					0		Acute lymphoblastic leukemia(13;3.76e-06)|all_hematologic(13;0.000303)|Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.00432)|Epithelial(162;0.0192)|all cancers(182;0.125)		CCAGTGGCCAGACCATTTTGC	0.577													41	489					0	0	0	0
DULLARD	23399	broad.mit.edu	37	17	7150389	7150389	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:7150389G>C	uc002gfd.2	-	3	662	c.282C>G	c.(280-282)ATC>ATG	p.I94M	DULLARD_uc002gfe.2_Missense_Mutation_p.I94M|DULLARD_uc002gff.2_Missense_Mutation_p.I94M|DULLARD_uc002gfc.2_RNA	NM_001143775	NP_001137247	O95476	CNEP1_HUMAN	dullard homolog	94	FCP1 homology.				nuclear envelope organization|protein dephosphorylation	endoplasmic reticulum membrane|integral to membrane|nuclear membrane	protein serine/threonine phosphatase activity				0						ACACCTTGAGGATGAAGTCAG	0.562													41	159					0	0	0	0
RICH2	9912	broad.mit.edu	37	17	12812249	12812249	+	Silent	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:12812249G>C	uc002gnr.3	+	4	561	c.234G>C	c.(232-234)CTG>CTC	p.L78L	RICH2_uc010vvk.1_Silent_p.L78L|RICH2_uc010vvl.1_Silent_p.L78L|RICH2_uc002gns.3_5'UTR|RICH2_uc010vvm.1_Silent_p.L78L|RICH2_uc010vvn.1_RNA	NM_014859	NP_055674	Q17R89	RHG44_HUMAN	Rho GTPase-activating protein RICH2	78	BAR.				regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytosol	GTPase activator activity				0						CTCAGTGTCTGATGGAGGGGT	0.428													21	337					0	0	0	0
SUZ12	23512	broad.mit.edu	37	17	30321584	30321584	+	Missense_Mutation	SNP	A	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:30321584A>G	uc002hgs.2	+	13	1661	c.1439A>G	c.(1438-1440)TAT>TGT	p.Y480C	SUZ12_uc002hgt.2_Missense_Mutation_p.Y457C	NM_015355	NP_056170	Q15022	SUZ12_HUMAN	joined to JAZF1	480					negative regulation of cell differentiation|transcription, DNA-dependent	ESC/E(Z) complex	histone methyltransferase activity|methylated histone residue binding|zinc ion binding		JAZF1/SUZ12(131)	soft_tissue(98)|endometrium(33)	131		Myeloproliferative disorder(56;0.0255)|all_hematologic(16;0.041)|Ovarian(249;0.182)|Breast(31;0.231)				TTGTTGCAGTATCATCCAAAA	0.323			T	JAZF1	endometrial stromal tumours								7	75					0	0	0	0
HOXB3	3213	broad.mit.edu	37	17	46627999	46627999	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:46627999C>T	uc002inn.2	-	2	1393	c.993G>A	c.(991-993)CCG>CCA	p.P331P	HOXB3_uc010wlm.1_Silent_p.P258P|HOXB3_uc010dbf.2_Silent_p.P331P|HOXB3_uc010dbg.2_Silent_p.P331P|HOXB3_uc002ino.2_Silent_p.P331P|HOXB3_uc010wlk.1_Silent_p.P199P|HOXB3_uc010wll.1_Silent_p.P258P	NM_002146	NP_002137	P14651	HXB3_HUMAN	homeobox B3	331					angiogenesis	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity				0						GGAGGACGTGCGGCTCATACT	0.716											OREG0024516	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	70					0	0	0	0
MTMR4	9110	broad.mit.edu	37	17	56582201	56582201	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:56582201C>T	uc002iwj.2	-	12	1348	c.1238G>A	c.(1237-1239)CGC>CAC	p.R413H		NM_004687	NP_004678	Q9NYA4	MTMR4_HUMAN	myotubularin related protein 4	413	Myotubularin phosphatase.|Substrate binding (By similarity).					cytoplasm|membrane	metal ion binding|protein tyrosine phosphatase activity			skin(1)	1	Medulloblastoma(34;0.127)|all_neural(34;0.237)					CTGCGGTGTGCGGTCCCAGCC	0.532													4	215					0	0	0	0
PTRH2	51651	broad.mit.edu	37	17	57775074	57775074	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:57775074G>A	uc002ixt.2	-	2	391	c.266C>T	c.(265-267)GCT>GTT	p.A89V	PTRH2_uc002ixs.2_RNA	NM_016077	NP_057161	Q9Y3E5	PTH2_HUMAN	Bcl-2 inhibitor of transcription precursor	89					apoptosis|translation	mitochondrion	aminoacyl-tRNA hydrolase activity				0	all_neural(34;0.0878)|Medulloblastoma(34;0.0922)					TGAAACAGCAGCATGAGAGCA	0.478													35	251					0	0	0	0
PITPNC1	26207	broad.mit.edu	37	17	65688860	65688860	+	Silent	SNP	C	T	T	rs146560406	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:65688860C>T	uc002jgc.2	+	9	1202	c.855C>T	c.(853-855)CCC>CCT	p.P285P	PITPNC1_uc002jgb.2_3'UTR	NM_012417	NP_036549	Q9UKF7	PITC1_HUMAN	phosphatidylinositol transfer protein,	285					signal transduction	cytoplasm	lipid binding|phosphatidylinositol transporter activity|protein binding			skin(1)	1	all_cancers(12;3.03e-10)		BRCA - Breast invasive adenocarcinoma(8;2.08e-08)|Colorectal(3;0.198)			CAGACGCACCCGAATTTCTGT	0.557													7	170					0	0	0	0
ABCA7	10347	broad.mit.edu	37	19	1043251	1043251	+	Splice_Site	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:1043251G>A	uc002lqw.3	+	8	1021	c.790_splice	c.e8+1	p.S264_splice	ABCA7_uc010dsb.1_Splice_Site_p.S126_splice	NM_019112	NP_061985	Q8IZY2	ABCA7_HUMAN	ATP-binding cassette, sub-family A, member 7						phagocytosis|transmembrane transport	ATP-binding cassette (ABC) transporter complex|endosome membrane|Golgi membrane|integral to membrane|plasma membrane	ATP binding|ATPase activity|transporter activity			pancreas(7)|ovary(1)|central_nervous_system(1)	9		Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;1.04e-05)|all_lung(49;1.53e-05)|Breast(49;9.42e-05)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		AGCAGCCTGAGTGAGTGACTG	0.657													17	168					0	0	0	0
MPND	84954	broad.mit.edu	37	19	4345805	4345805	+	Missense_Mutation	SNP	A	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:4345805A>T	uc002mae.2	+	3	425	c.358A>T	c.(358-360)ACC>TCC	p.T120S	MPND_uc010dtx.2_RNA|MPND_uc002mag.2_Missense_Mutation_p.T120S|MPND_uc002maf.2_Missense_Mutation_p.T120S|MPND_uc002mah.2_Missense_Mutation_p.T8S|MPND_uc002mai.2_Missense_Mutation_p.T8S	NM_032868	NP_116257	Q8N594	MPND_HUMAN	MPN domain containing isoform 1	120							peptidase activity			breast(1)	1				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0149)|STAD - Stomach adenocarcinoma(1328;0.18)		GACCGGGCAGACCTTCAACTC	0.622													9	86					0	0	0	0
MPND	84954	broad.mit.edu	37	19	4357346	4357346	+	Missense_Mutation	SNP	G	A	A	rs61730129		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:4357346G>A	uc002mae.2	+	9	1160	c.1093G>A	c.(1093-1095)GCA>ACA	p.A365T	MPND_uc010dtx.2_RNA|MPND_uc002mag.2_Missense_Mutation_p.A315T|MPND_uc002maf.2_Missense_Mutation_p.A365T|MPND_uc002mah.2_Missense_Mutation_p.A253T|MPND_uc002mai.2_Missense_Mutation_p.A224T	NM_032868	NP_116257	Q8N594	MPND_HUMAN	MPN domain containing isoform 1	365	MPN.						peptidase activity			breast(1)	1				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0149)|STAD - Stomach adenocarcinoma(1328;0.18)		GGACATCGACGCACAGATGGA	0.672													9	41					0	0	0	0
RFX1	5989	broad.mit.edu	37	19	14079491	14079491	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:14079491G>T	uc002mxv.2	-	12	1890	c.1618C>A	c.(1618-1620)CTC>ATC	p.L540I		NM_002918	NP_002909	P22670	RFX1_HUMAN	regulatory factor X1	540					immune response	nucleus	DNA binding|protein binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity			lung(1)|pancreas(1)	2			OV - Ovarian serous cystadenocarcinoma(19;6.67e-23)			ATGGGCTTGAGCCTGGAGTAG	0.692													6	52					2.7689e-08	3.2139e-08	1	0
MED26	9441	broad.mit.edu	37	19	16687957	16687957	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:16687957C>T	uc002nen.1	-	3	945	c.684G>A	c.(682-684)CCG>CCA	p.P228P	MED26_uc002nee.2_RNA	NM_004831	NP_004822	O95402	MED26_HUMAN	mediator complex subunit 26	228	Pro-rich.				regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter	mediator complex	DNA binding|RNA polymerase II transcription cofactor activity|transcription coactivator activity			ovary(2)	2						AGCTGGTGTGCGGTCGCACGG	0.682													8	113					0	0	0	0
LSR	51599	broad.mit.edu	37	19	35758624	35758624	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:35758624G>A	uc002nyl.2	+	9	2124	c.1901G>A	c.(1900-1902)CGC>CAC	p.R634H	LSR_uc002nym.2_Missense_Mutation_p.R615H|LSR_uc002nyn.2_Missense_Mutation_p.R566H|LSR_uc002nyo.2_Missense_Mutation_p.R614H|LSR_uc010xsr.1_Missense_Mutation_p.R526H|LSR_uc002nyp.2_Missense_Mutation_p.R576H|USF2_uc010xss.1_5'Flank|USF2_uc002nyq.1_5'Flank|USF2_uc002nyr.1_5'Flank|USF2_uc002nys.1_5'Flank|USF2_uc002nyt.1_5'Flank|USF2_uc002nyu.1_5'Flank|USF2_uc002nyv.1_5'Flank	NM_205834	NP_991403	Q86X29	LSR_HUMAN	lipolysis stimulated lipoprotein receptor	634	Cytoplasmic (Potential).				embryo development|liver development	chylomicron|integral to membrane|low-density lipoprotein particle|plasma membrane|very-low-density lipoprotein particle	receptor activity				0	all_lung(56;3.91e-09)|Lung NSC(56;5.64e-09)|Esophageal squamous(110;0.162)		Epithelial(14;1.33e-19)|OV - Ovarian serous cystadenocarcinoma(14;1.29e-18)|all cancers(14;7.11e-17)|LUSC - Lung squamous cell carcinoma(66;0.0417)			TCCCGAGAGCGCAGGCTCAAG	0.567													4	151					0	0	0	0
SUPT5H	6829	broad.mit.edu	37	19	39964120	39964120	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:39964120G>C	uc002olo.3	+	25	2630	c.2451G>C	c.(2449-2451)CAG>CAC	p.Q817H	SUPT5H_uc002olp.3_Missense_Mutation_p.Q817H|SUPT5H_uc002olq.3_Missense_Mutation_p.Q813H|SUPT5H_uc002oln.3_Missense_Mutation_p.Q817H|SUPT5H_uc002olr.3_Missense_Mutation_p.Q817H|SUPT5H_uc002ols.1_Missense_Mutation_p.Q440H|SUPT5H_uc010egp.1_3'UTR	NM_001111020	NP_001104490	O00267	SPT5H_HUMAN	suppressor of Ty 5 homolog isoform a	817	CTR1-9.|9 X 7 AA approximate tandem repeats of G- S-[QR]-T-P-X-[YQ], motif CTR1.				cell cycle|chromatin remodeling|mRNA capping|negative regulation of transcription elongation, DNA-dependent|negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription elongation from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of viral transcription|response to organic substance|retroviral genome replication|transcription elongation from RNA polymerase II promoter	nucleoplasm	enzyme binding|protein heterodimerization activity			ovary(3)|pancreas(1)	4	all_cancers(60;6.69e-07)|all_lung(34;2.66e-08)|Lung NSC(34;3e-08)|all_epithelial(25;1.57e-06)|Ovarian(47;0.159)		Epithelial(26;3.9e-26)|all cancers(26;1.35e-23)|LUSC - Lung squamous cell carcinoma(53;0.000657)			CTCCTGCCCAGAGTGGGGCCT	0.632													13	107					0	0	0	0
RPS19	6223	broad.mit.edu	37	19	42373230	42373230	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:42373230G>A	uc002ort.2	+	4	674	c.302G>A	c.(301-303)CGC>CAC	p.R101H		NM_001022	NP_001013	P39019	RS19_HUMAN	ribosomal protein S19	101			R -> H (in DBA1; increased protein degradation; affects assembly into a functional ribosomal subunit).		endocrine pancreas development|erythrocyte differentiation|gas transport|positive regulation of cellular component movement|response to extracellular stimulus|ribosomal small subunit biogenesis|rRNA processing|translational elongation|translational termination|viral transcription	cytosolic small ribosomal subunit|nucleolus	protein binding|RNA binding|structural constituent of ribosome				0						AGTGTGGCCCGCCGGGTCCTC	0.617									Diamond-Blackfan_Anemia				6	59					0	0	0	0
ZNF574	64763	broad.mit.edu	37	19	42583864	42583864	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:42583864G>T	uc002osm.3	+	2	1275	c.1106G>T	c.(1105-1107)TGT>TTT	p.C369F	ZNF574_uc002osk.3_Missense_Mutation_p.C459F	NM_022752	NP_073589	Q6ZN55	ZN574_HUMAN	zinc finger protein 574	369	C2H2-type 7.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		Prostate(69;0.059)				TGTGTAGACTGTGGCCTGGCC	0.592													8	96					0.000274275	0.000298791	1	0
PSG4	5672	broad.mit.edu	37	19	43699348	43699348	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:43699348C>T	uc002ovy.2	-	4	889	c.787G>A	c.(787-789)GAA>AAA	p.E263K	PSG6_uc010xwk.1_Intron|PSG4_uc002owa.2_RNA|PSG4_uc002owb.2_Missense_Mutation_p.E170K|PSG4_uc002ovz.2_Intron	NM_002780	NP_002771	Q00888	PSG4_HUMAN	pregnancy specific beta-1-glycoprotein 4 isoform	263	Ig-like C2-type 2.				defense response|female pregnancy	extracellular region				ovary(1)	1		Prostate(69;0.00682)				CTCTTAGGTTCACAGGTGAAG	0.453													39	416					0	0	0	0
ERCC2	2068	broad.mit.edu	37	19	45860923	45860923	+	Silent	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:45860923T>C	uc002pbj.2	-	13	1319	c.1272A>G	c.(1270-1272)AGA>AGG	p.R424R	ERCC2_uc002pbh.2_5'UTR|ERCC2_uc002pbi.2_Silent_p.R117R|ERCC2_uc010ejz.2_Silent_p.R346R|ERCC2_uc002pbk.2_Silent_p.R400R	NM_000400	NP_000391	P18074	ERCC2_HUMAN	excision repair cross-complementing rodent	424					cell cycle checkpoint|chromosome segregation|hair cell differentiation|induction of apoptosis|interspecies interaction between organisms|mRNA capping|nucleotide-excision repair, DNA damage removal|nucleotide-excision repair, DNA incision|positive regulation of transcription from RNA polymerase II promoter|positive regulation of viral transcription|protein phosphorylation|response to oxidative stress|termination of RNA polymerase I transcription|transcription elongation from RNA polymerase I promoter|transcription elongation from RNA polymerase II promoter|transcription initiation from RNA polymerase I promoter|transcription initiation from RNA polymerase II promoter|transcription-coupled nucleotide-excision repair|UV protection|viral reproduction	cytoplasm|holo TFIIH complex|MMXD complex	5'-3' DNA helicase activity|ATP binding|ATP-dependent DNA helicase activity|DNA binding|iron-sulfur cluster binding|metal ion binding|protein C-terminus binding|protein N-terminus binding			lung(2)|pancreas(1)	3		Ovarian(192;0.0728)|all_neural(266;0.112)		OV - Ovarian serous cystadenocarcinoma(262;0.0226)		TGGTCGGGGTTCTGTCGTCAA	0.637			Mis|N|F|S			skin basal cell|skin squamous cell|melanoma		Direct_reversal_of_damage|NER	Xeroderma_Pigmentosum				8	65					0	0	0	0
ZC3H4	23211	broad.mit.edu	37	19	47588318	47588318	+	Missense_Mutation	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:47588318T>C	uc002pga.3	-	8	1140	c.1102A>G	c.(1102-1104)ATG>GTG	p.M368V	ZC3H4_uc002pgb.1_Intron	NM_015168	NP_055983	Q9UPT8	ZC3H4_HUMAN	zinc finger CCCH-type containing 4	368	Gly-rich.						nucleic acid binding|zinc ion binding			skin(4)|ovary(2)	6		all_cancers(25;3.3e-08)|all_epithelial(76;2.28e-06)|all_lung(116;7.86e-06)|Lung NSC(112;2.31e-05)|all_neural(266;0.026)|Ovarian(192;0.0392)|Breast(70;0.0889)		OV - Ovarian serous cystadenocarcinoma(262;5.76e-05)|all cancers(93;7.69e-05)|Epithelial(262;0.00354)|GBM - Glioblastoma multiforme(486;0.0372)		CTCACGCCCATGTCCTCGTCA	0.532													56	331					0	0	0	0
RASIP1	54922	broad.mit.edu	37	19	49224087	49224087	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:49224087G>A	uc002pki.2	-	12	3057	c.2860C>T	c.(2860-2862)CGC>TGC	p.R954C	MAMSTR_uc002pkg.2_5'Flank|RASIP1_uc002pkh.2_Missense_Mutation_p.R215C	NM_017805	NP_060275	Q5U651	RAIN_HUMAN	Ras-interacting protein 1	954					signal transduction	Golgi stack|perinuclear region of cytoplasm				pancreas(1)	1		all_lung(116;4.89e-06)|all_epithelial(76;7.04e-06)|Lung NSC(112;9.34e-06)|all_neural(266;0.0189)|Ovarian(192;0.0261)		OV - Ovarian serous cystadenocarcinoma(262;9.98e-05)|all cancers(93;0.000272)|Epithelial(262;0.0155)|GBM - Glioblastoma multiforme(486;0.0222)		GGCCCATGGCGATAATTGGCT	0.612													12	246					0	0	0	0
ZNF473	25888	broad.mit.edu	37	19	50549541	50549541	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:50549541C>G	uc002prn.2	+	5	2078	c.1841C>G	c.(1840-1842)TCT>TGT	p.S614C	ZNF473_uc002prm.2_Missense_Mutation_p.S614C|ZNF473_uc010ybo.1_Missense_Mutation_p.S602C	NM_001006656	NP_001006657	Q8WTR7	ZN473_HUMAN	zinc finger protein 473	614					histone mRNA 3'-end processing|regulation of transcription, DNA-dependent|termination of RNA polymerase II transcription	Cajal body	DNA binding|protein binding|zinc ion binding			ovary(1)|central_nervous_system(1)	2		all_neural(266;0.0459)|Ovarian(192;0.0728)		GBM - Glioblastoma multiforme(134;0.00111)|OV - Ovarian serous cystadenocarcinoma(262;0.0058)		AGAATCCACTCTAGAGTGAGG	0.488													7	74					0	0	0	0
ZFP28	140612	broad.mit.edu	37	19	57065936	57065936	+	Silent	SNP	C	T	T	rs61734808	byFrequency	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:57065936C>T	uc002qnj.2	+	8	1853	c.1782C>T	c.(1780-1782)TGC>TGT	p.C594C	uc002qnk.1_Intron	NM_020828	NP_065879	Q8NHY6	ZFP28_HUMAN	zinc finger protein 28	594	C2H2-type 7.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)	1		Colorectal(82;0.000256)|Ovarian(87;0.243)		GBM - Glioblastoma multiforme(193;0.0302)		GTAAAGAGTGCGGAAAAGCTT	0.413													4	238					0	0	0	0
ZNF606	80095	broad.mit.edu	37	19	58489924	58489924	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:58489924G>A	uc002qqw.2	-	7	2742	c.2124C>T	c.(2122-2124)TAC>TAT	p.Y708Y	ZNF606_uc010yhp.1_Silent_p.Y618Y	NM_025027	NP_079303	Q8WXB4	ZN606_HUMAN	zinc finger protein 606	708	C2H2-type 14.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			upper_aerodigestive_tract(1)|ovary(1)	2		Colorectal(82;5.46e-05)|all_neural(62;0.0182)|Breast(46;0.0389)|Ovarian(87;0.0443)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0168)		CATTACACCTGTATGGTTTCT	0.393													23	147					0	0	0	0
ZNF329	79673	broad.mit.edu	37	19	58639690	58639690	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:58639690G>A	uc002qrn.2	-	4	1418	c.1181C>T	c.(1180-1182)TCT>TTT	p.S394F	ZNF329_uc010euk.1_RNA|ZNF329_uc002qro.1_RNA|ZNF329_uc002qrp.1_RNA	NM_024620	NP_078896	Q86UD4	ZN329_HUMAN	zinc finger protein 329	394					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			skin(1)	1		Colorectal(82;5.46e-05)|all_neural(62;0.0182)|Breast(46;0.029)|Ovarian(87;0.0443)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.017)|Lung(386;0.216)		TTTCTCCCCAGAATGGATCTT	0.468													18	177					0	0	0	0
ZSCAN22	342945	broad.mit.edu	37	19	58849700	58849700	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:58849700G>C	uc002qsc.2	+	3	631	c.484G>C	c.(484-486)GAG>CAG	p.E162Q	ZSCAN22_uc010yhz.1_Silent_p.L156L	NM_181846	NP_862829	P10073	ZSC22_HUMAN	zinc finger and SCAN domain containing 22	162					viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			pancreas(1)	1		all_cancers(17;3.11e-12)|all_epithelial(17;9.43e-09)|Colorectal(82;0.000256)|Lung NSC(17;0.000607)|all_lung(17;0.0024)|all_neural(62;0.0412)|Ovarian(87;0.156)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0289)		AAATGTCACTGAGACCCTCAT	0.567													13	141					0	0	0	0
ADCY3	109	broad.mit.edu	37	2	25062774	25062774	+	Silent	SNP	T	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:25062774T>A	uc002rfs.3	-	6	1522	c.1323A>T	c.(1321-1323)GTA>GTT	p.V441V	ADCY3_uc002rfr.3_Silent_p.V52V|ADCY3_uc010ykm.1_Silent_p.V441V	NM_004036	NP_004027	O60266	ADCY3_HUMAN	adenylate cyclase 3	441	Cytoplasmic (Potential).				activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity|activation of protein kinase A activity|cellular response to glucagon stimulus|energy reserve metabolic process|inhibition of adenylate cyclase activity by G-protein signaling pathway|nerve growth factor receptor signaling pathway|sensory perception of smell|synaptic transmission|transmembrane transport|water transport	cytoplasm|integral to plasma membrane	ATP binding|calmodulin binding|metal ion binding			breast(3)|ovary(1)	4	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.203)					TCTTGTTGGCTACAGTGACAT	0.672													26	152					0	0	0	0
EMILIN1	11117	broad.mit.edu	37	2	27306220	27306220	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:27306220G>A	uc002rii.3	+	4	2209	c.1781G>A	c.(1780-1782)CGC>CAC	p.R594H	EMILIN1_uc002rik.3_5'Flank	NM_007046	NP_008977	Q9Y6C2	EMIL1_HUMAN	elastin microfibril interfacer 1 precursor	594	Potential.				cell adhesion	collagen				pancreas(1)	1	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					GAACTAGGCCGCCTTCGGGAT	0.697													19	97					0	0	0	0
CNGA3	1261	broad.mit.edu	37	2	99012566	99012566	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:99012566C>T	uc002syt.2	+	8	1350	c.933C>T	c.(931-933)CTC>CTT	p.L311L	CNGA3_uc002syu.2_Silent_p.L293L|CNGA3_uc010fij.2_Silent_p.L315L	NM_001298	NP_001289	Q16281	CNGA3_HUMAN	cyclic nucleotide gated channel alpha 3 isoform	311	Helical; (Potential).				signal transduction|visual perception	integral to membrane	cGMP binding			ovary(5)|upper_aerodigestive_tract(1)	6						TGTACATTCTCATCATCATCC	0.458													17	175					0	0	0	0
AFF3	3899	broad.mit.edu	37	2	100623856	100623856	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:100623856C>G	uc002tag.2	-	5	477	c.241G>C	c.(241-243)GAC>CAC	p.D81H	AFF3_uc002taf.2_Missense_Mutation_p.D106H|AFF3_uc010fiq.1_Missense_Mutation_p.D81H|AFF3_uc010yvr.1_Missense_Mutation_p.D235H|AFF3_uc002tah.1_Missense_Mutation_p.D106H|AFF3_uc010fir.1_Missense_Mutation_p.D158H|AFF3_uc002tai.2_Missense_Mutation_p.D3H	NM_002285	NP_002276	P51826	AFF3_HUMAN	AF4/FMR2 family, member 3 isoform 1	81					multicellular organismal development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding			ovary(2)|pancreas(1)|lung(1)|kidney(1)|skin(1)	6						GTTAAAAAGTCTTTCATTTCA	0.418													32	161					0	0	0	0
SCN9A	6335	broad.mit.edu	37	2	167055509	167055509	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:167055509G>C	uc010fpl.2	-	27	5948	c.5607C>G	c.(5605-5607)ATC>ATG	p.I1869M	uc002udp.2_Intron	NM_002977	NP_002968	Q15858	SCN9A_HUMAN	sodium channel, voltage-gated, type IX, alpha	1880						voltage-gated sodium channel complex	voltage-gated sodium channel activity			ovary(6)|central_nervous_system(5)|skin(2)	13					Lamotrigine(DB00555)|Lidocaine(DB00281)	GTGTGGTTGTGATGGGTTCAT	0.428													29	177					0	0	0	0
LRP2	4036	broad.mit.edu	37	2	170042510	170042510	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:170042510G>T	uc002ues.2	-	50	9561	c.9348C>A	c.(9346-9348)GAC>GAA	p.D3116E		NM_004525	NP_004516	P98164	LRP2_HUMAN	low density lipoprotein-related protein 2	3116	EGF-like 11.|Extracellular (Potential).				hormone biosynthetic process|protein glycosylation|receptor-mediated endocytosis|vitamin D metabolic process	coated pit|integral to membrane|lysosome	calcium ion binding|receptor activity|SH3 domain binding			ovary(13)|skin(6)|central_nervous_system(4)|large_intestine(3)|kidney(2)|pancreas(1)	29				STAD - Stomach adenocarcinoma(1183;0.000766)|COAD - Colon adenocarcinoma(177;0.0101)	Gentamicin(DB00798)|Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)|Urokinase(DB00013)	TGATTGAAGGGTCATGGCATT	0.418													19	76					2.39187e-15	2.952e-15	1	0
FASTKD1	79675	broad.mit.edu	37	2	170403114	170403114	+	Missense_Mutation	SNP	T	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:170403114T>A	uc002uev.3	-	8	1703	c.1315A>T	c.(1315-1317)ATT>TTT	p.I439F	FASTKD1_uc002uew.3_RNA|FASTKD1_uc002uex.3_Missense_Mutation_p.I425F	NM_024622	NP_078898	Q53R41	FAKD1_HUMAN	FAST kinase domains 1	439					apoptosis|cellular respiration	mitochondrion	ATP binding|protein kinase activity			ovary(4)	4						ACGGCTTCAATTCGGGATATC	0.408													13	105					0	0	0	0
ANKAR	150709	broad.mit.edu	37	2	190608094	190608094	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:190608094C>G	uc002uqw.1	+	20	3691	c.3691C>G	c.(3691-3693)CAG>GAG	p.Q1231E	ANKAR_uc002uqu.2_RNA|ANKAR_uc002uqx.1_RNA|ANKAR_uc002uqy.1_Intron	NM_144708	NP_653309	Q7Z5J8	ANKAR_HUMAN	ankyrin and armadillo repeat containing	1302						integral to membrane	binding			ovary(2)|pancreas(1)|skin(1)	4			OV - Ovarian serous cystadenocarcinoma(117;0.00156)|Epithelial(96;0.0256)|all cancers(119;0.0744)			TAAACCTAATCAGTTCATTCG	0.368													12	78					0	0	0	0
PIKFYVE	200576	broad.mit.edu	37	2	209138378	209138378	+	Silent	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:209138378G>T	uc002vcz.2	+	3	401	c.243G>T	c.(241-243)TCG>TCT	p.S81S	PIKFYVE_uc010fun.1_5'UTR|PIKFYVE_uc002vcy.1_Silent_p.S81S|PIKFYVE_uc002vcv.2_Silent_p.S81S|PIKFYVE_uc002vcw.2_Silent_p.S81S|PIKFYVE_uc002vcx.2_Silent_p.S81S	NM_015040	NP_055855	Q9Y2I7	FYV1_HUMAN	phosphatidylinositol-3-phosphate 5-kinase type	81					cellular protein metabolic process|intracellular signal transduction|protein localization to nucleus|retrograde transport, endosome to Golgi	early endosome membrane|membrane raft	1-phosphatidylinositol-3-phosphate 5-kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|ATP binding|metal ion binding|protein binding			ovary(5)|kidney(2)|pancreas(1)|central_nervous_system(1)|skin(1)	10						AGCTCCCTTCGAGGACACAGT	0.493													10	122					0.000442599	0.000479483	1	0
VIL1	7429	broad.mit.edu	37	2	219314035	219314035	+	Silent	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:219314035C>G	uc002via.2	+	20	2525	c.2460C>G	c.(2458-2460)CTC>CTG	p.L820L	VIL1_uc010zke.1_Silent_p.L509L|VIL1_uc002vib.2_Silent_p.L820L	NM_007127	NP_009058	P09327	VILI_HUMAN	villin 1	820	Headpiece.|HP.|LPA/PIP2-binding site 3.				actin filament capping|actin filament depolymerization|actin filament polymerization|actin filament severing|apoptosis|cellular response to epidermal growth factor stimulus|cytoplasmic actin-based contraction involved in cell motility|epidermal growth factor receptor signaling pathway|positive regulation of actin filament bundle assembly|positive regulation of epithelial cell migration|regulation of actin nucleation|regulation of cell shape|regulation of lamellipodium morphogenesis|regulation of wound healing|response to bacterium	actin filament bundle|cytoplasm|filopodium tip|intracellular membrane-bounded organelle|lamellipodium|microvillus|ruffle	actin filament binding|calcium ion binding|caspase inhibitor activity|lysophosphatidic acid binding|phosphatidylinositol-4,5-bisphosphate binding|protein homodimerization activity			ovary(1)	1		Renal(207;0.0474)		Epithelial(149;6.88e-07)|all cancers(144;0.00013)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		AACAAAACCTCAAGAAAGAAA	0.448													34	245					0	0	0	0
WDFY1	57590	broad.mit.edu	37	2	224809872	224809872	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:224809872C>T	uc002vnq.2	-	1	181	c.130G>A	c.(130-132)GAG>AAG	p.E44K		NM_020830	NP_065881	Q8IWB7	WDFY1_HUMAN	WD repeat and FYVE domain containing 1	44	WD 1.					cytosol|early endosome|nucleus	1-phosphatidylinositol binding|zinc ion binding			lung(1)	1		all_lung(227;0.00682)|Lung NSC(271;0.00859)|Renal(207;0.0112)|all_hematologic(139;0.189)		Epithelial(121;5.34e-10)|all cancers(144;1.67e-07)|Lung(261;0.00807)|LUSC - Lung squamous cell carcinoma(224;0.00843)		TACCTGTCCTCGCTGGCCGTG	0.751													5	26					0	0	0	0
MKKS	8195	broad.mit.edu	37	20	10393770	10393770	+	Silent	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:10393770G>C	uc002wnt.1	-	3	1280	c.393C>G	c.(391-393)CTC>CTG	p.L131L	MKKS_uc002wnu.1_Silent_p.L131L|MKKS_uc010zrd.1_Intron	NM_018848	NP_061336	Q9NPJ1	MKKS_HUMAN	McKusick-Kaufman syndrome protein	131					brain morphogenesis|cerebral cortex development|convergent extension involved in gastrulation|detection of mechanical stimulus involved in sensory perception of sound|fat cell differentiation|flagellum assembly|gonad development|heart looping|hippocampus development|intracellular transport|melanosome transport|photoreceptor cell maintenance|pigment granule aggregation in cell center|protein folding|regulation of cilium beat frequency involved in ciliary motility|sensory perception of smell|social behavior|spermatid development|striatum development	cytosol|microtubule organizing center|motile cilium	ATP binding|unfolded protein binding				0						TCTCAGACTTGAGATAACTGA	0.398									Bardet-Biedl_syndrome				5	87					0	0	0	0
MKKS	8195	broad.mit.edu	37	20	10393844	10393844	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:10393844G>C	uc002wnt.1	-	3	1206	c.319C>G	c.(319-321)CAG>GAG	p.Q107E	MKKS_uc002wnu.1_Missense_Mutation_p.Q107E|MKKS_uc010zrd.1_Intron	NM_018848	NP_061336	Q9NPJ1	MKKS_HUMAN	McKusick-Kaufman syndrome protein	107					brain morphogenesis|cerebral cortex development|convergent extension involved in gastrulation|detection of mechanical stimulus involved in sensory perception of sound|fat cell differentiation|flagellum assembly|gonad development|heart looping|hippocampus development|intracellular transport|melanosome transport|photoreceptor cell maintenance|pigment granule aggregation in cell center|protein folding|regulation of cilium beat frequency involved in ciliary motility|sensory perception of smell|social behavior|spermatid development|striatum development	cytosol|microtubule organizing center|motile cilium	ATP binding|unfolded protein binding				0						CCTAATCTCTGAACATTTTCA	0.393									Bardet-Biedl_syndrome				10	90					0	0	0	0
MKKS	8195	broad.mit.edu	37	20	10393971	10393971	+	Silent	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:10393971G>C	uc002wnt.1	-	3	1079	c.192C>G	c.(190-192)CTC>CTG	p.L64L	MKKS_uc002wnu.1_Silent_p.L64L|MKKS_uc010zrd.1_Intron	NM_018848	NP_061336	Q9NPJ1	MKKS_HUMAN	McKusick-Kaufman syndrome protein	64					brain morphogenesis|cerebral cortex development|convergent extension involved in gastrulation|detection of mechanical stimulus involved in sensory perception of sound|fat cell differentiation|flagellum assembly|gonad development|heart looping|hippocampus development|intracellular transport|melanosome transport|photoreceptor cell maintenance|pigment granule aggregation in cell center|protein folding|regulation of cilium beat frequency involved in ciliary motility|sensory perception of smell|social behavior|spermatid development|striatum development	cytosol|microtubule organizing center|motile cilium	ATP binding|unfolded protein binding				0						AAAGGTGACTGAGCAGAGCTG	0.468									Bardet-Biedl_syndrome				10	112					0	0	0	0
L3MBTL	26013	broad.mit.edu	37	20	42144745	42144745	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:42144745G>C	uc010zwh.1	+	7	770	c.724G>C	c.(724-726)GAA>CAA	p.E242Q	L3MBTL_uc010ggk.1_Missense_Mutation_p.E174Q|L3MBTL_uc002xkl.2_Missense_Mutation_p.E174Q|L3MBTL_uc002xkm.2_Missense_Mutation_p.E174Q|L3MBTL_uc010ggl.2_Missense_Mutation_p.E174Q	NM_015478	NP_056293	Q9Y468	LMBL1_HUMAN	l(3)mbt-like isoform I	174					chromatin modification|hemopoiesis|negative regulation of transcription, DNA-dependent|regulation of megakaryocyte differentiation|regulation of mitosis	chromatin|condensed chromosome|nucleoplasm	identical protein binding|methylated histone residue binding|nucleosomal histone binding|SAM domain binding|sequence-specific DNA binding transcription factor activity|zinc ion binding				0		Myeloproliferative disorder(115;0.00452)	COAD - Colon adenocarcinoma(18;0.0031)			GAAGCAAGAAGAAGGAAAGGA	0.552													5	73					0	0	0	0
HNF4A	3172	broad.mit.edu	37	20	43030122	43030122	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:43030122G>A	uc002xma.2	+	1	199	c.110G>A	c.(109-111)GGC>GAC	p.G37D	HNF4A_uc010zwo.1_Intron|HNF4A_uc002xlt.2_Intron|HNF4A_uc002xlu.2_Intron|HNF4A_uc002xlv.2_Intron|uc002xlw.1_Intron|HNF4A_uc002xly.2_Missense_Mutation_p.G37D|HNF4A_uc002xlz.2_Missense_Mutation_p.G37D|HNF4A_uc010ggq.2_5'UTR	NM_000457	NP_000448	P41235	HNF4A_HUMAN	hepatocyte nuclear factor 4 alpha isoform b	37					blood coagulation|endocrine pancreas development|glucose homeostasis|negative regulation of cell growth|negative regulation of cell proliferation|ornithine metabolic process|phospholipid homeostasis|positive regulation of cholesterol homeostasis|regulation of growth hormone receptor signaling pathway|regulation of insulin secretion|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|response to glucose stimulus|triglyceride homeostasis|xenobiotic metabolic process	cytoplasm	activating transcription factor binding|protein homodimerization activity|receptor binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|steroid hormone receptor activity|transcription regulatory region DNA binding|zinc ion binding			ovary(1)|lung(1)|skin(1)	3		Myeloproliferative disorder(115;0.0122)	COAD - Colon adenocarcinoma(18;0.00189)			TTGACGATGGGCAATGGTAGG	0.587													10	96					0	0	0	0
SLPI	6590	broad.mit.edu	37	20	43882277	43882277	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:43882277C>T	uc002xnm.1	-	2	205	c.183G>A	c.(181-183)AAG>AAA	p.K61K		NM_003064	NP_003055	P03973	SLPI_HUMAN	secretory leukocyte peptidase inhibitor	61	Trypsin inhibitory domain.|WAP 1.					extracellular region	serine-type endopeptidase inhibitor activity			ovary(1)	1		Myeloproliferative disorder(115;0.0122)				GACAACATCTCTTCTTCCCTG	0.517													5	74					0	0	0	0
PES1	23481	broad.mit.edu	37	22	30985250	30985250	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr22:30985250C>T	uc003aij.1	-	2	106	c.32G>A	c.(31-33)CGA>CAA	p.R11Q	PES1_uc003aik.1_Missense_Mutation_p.R11Q|PES1_uc003ail.1_Missense_Mutation_p.R11Q|PES1_uc003aim.1_Missense_Mutation_p.R11Q|PES1_uc003ain.1_5'UTR|PES1_uc003aio.1_5'UTR	NM_014303	NP_055118	O00541	PESC_HUMAN	pescadillo homolog 1, containing BRCT domain	11	Sufficient for nucleolar localization.|Required for 28S ribosomal RNA processing.				cell proliferation|maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|regulation of cell cycle	chromosome|nucleoplasm|PeBoW complex|preribosome, large subunit precursor	protein binding				0						GGCCGAGCCTCGTTCATACTG	0.498													4	49					0	0	0	0
MYH9	4627	broad.mit.edu	37	22	36712581	36712581	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr22:36712581G>A	uc003apg.2	-	12	1592	c.1361C>T	c.(1360-1362)GCC>GTC	p.A454V	MYH9_uc003aph.1_Missense_Mutation_p.A318V	NM_002473	NP_002464	P35579	MYH9_HUMAN	myosin, heavy polypeptide 9, non-muscle	454	Myosin head-like.				actin cytoskeleton reorganization|actin filament-based movement|angiogenesis|axon guidance|blood vessel endothelial cell migration|cytokinesis|integrin-mediated signaling pathway|leukocyte migration|membrane protein ectodomain proteolysis|monocyte differentiation|platelet formation|protein transport|regulation of cell shape	actomyosin contractile ring|cleavage furrow|cytosol|myosin complex|nucleus|ruffle|stress fiber|uropod	actin filament binding|actin-dependent ATPase activity|ADP binding|ATP binding|calmodulin binding|microfilament motor activity|protein anchor|protein homodimerization activity			breast(3)|ovary(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)|lung(1)|skin(1)|kidney(1)|pancreas(1)	11						CTCGAAGCCGGCAATGTCCAG	0.562			T	ALK	ALCL		Deafness|autosomal dominant 17|Epstein syndrome|Fechtner syndrome|May-Hegglin anomaly|Sebastian syndrome		Hereditary_Macrothrombocytopenia_MYH9-associated				4	236					0	0	0	0
GRIP2	80852	broad.mit.edu	37	3	14562009	14562009	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:14562009C>T	uc011avi.1	-	9	1039	c.1039G>A	c.(1039-1041)GAA>AAA	p.E347K	GRIP2_uc011avh.1_5'UTR	NM_001080423	NP_001073892	Q9C0E4	GRIP2_HUMAN	glutamate receptor interacting protein 2	250	PDZ 3.				synaptic transmission	cytosol|plasma membrane	protein binding			pancreas(1)	1						TTGACTATTTCCACCATCAAG	0.552													4	38					0	0	0	0
THRB	7068	broad.mit.edu	37	3	24174936	24174936	+	Missense_Mutation	SNP	T	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:24174936T>G	uc003ccx.3	-	9	1105	c.756A>C	c.(754-756)CAA>CAC	p.Q252H	THRB_uc010hfe.2_Missense_Mutation_p.Q252H|THRB_uc003ccy.3_Missense_Mutation_p.Q252H|THRB_uc003ccz.3_Missense_Mutation_p.Q247H	NM_001128176	NP_001121648	P10828	THB_HUMAN	thyroid hormone receptor, beta	252	Ligand-binding.|Interaction with NR2F6.				regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	nucleoplasm	enzyme binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|thyroid hormone receptor activity|transcription corepressor activity|zinc ion binding			skin(2)|pancreas(1)	3					Levothyroxine(DB00451)|Liothyronine(DB00279)	CTATTGGTGCTTGTCCAATGT	0.393													5	82					0	0	0	0
C3orf23	285343	broad.mit.edu	37	3	44437946	44437946	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:44437946C>T	uc010him.2	+	7	995	c.750C>T	c.(748-750)AGC>AGT	p.S250S	C3orf23_uc003cnd.3_Silent_p.S250S|C3orf23_uc003cne.3_Silent_p.S106S	NM_173826	NP_776187	Q8N3R3	CC023_HUMAN	hypothetical protein LOC285343 isoform 1	250						mitochondrion				upper_aerodigestive_tract(1)|ovary(1)|skin(1)	3				KIRC - Kidney renal clear cell carcinoma(197;0.0468)|Kidney(197;0.0585)		ATAGTTTAAGCCGCTTAGCAC	0.438													3	40					0	0	0	0
ZNF660	285349	broad.mit.edu	37	3	44635868	44635868	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:44635868G>A	uc003cnl.1	+	3	516	c.183G>A	c.(181-183)CAG>CAA	p.Q61Q		NM_173658	NP_775929	Q6AZW8	ZN660_HUMAN	zinc finger protein 660	61	C2H2-type 1.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0				KIRC - Kidney renal clear cell carcinoma(197;0.0468)|Kidney(197;0.0585)		CCTTTAGTCAGAGTGCAAACC	0.438													6	63					0	0	0	0
NME6	10201	broad.mit.edu	37	3	48336722	48336722	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:48336722C>T	uc003csp.3	-	5	288	c.237G>A	c.(235-237)GGG>GGA	p.G79G	NME6_uc003cso.2_Silent_p.G87G|NME6_uc011bbh.1_Missense_Mutation_p.G66D|NME6_uc010hju.2_5'UTR|NME6_uc011bbi.1_Intron	NM_005793	NP_005784	O75414	NDK6_HUMAN	nucleoside diphosphate kinase type 6	79					anti-apoptosis|apoptosis|CTP biosynthetic process|GTP biosynthetic process|negative regulation of cell growth|negative regulation of mitosis|UTP biosynthetic process	mitochondrion	ATP binding|metal ion binding|nucleoside diphosphate kinase activity				0				BRCA - Breast invasive adenocarcinoma(193;0.00029)|KIRC - Kidney renal clear cell carcinoma(197;0.00544)|Kidney(197;0.00609)		CTCGGATTGGCCCGCTGTGAA	0.552													3	37					0	0	0	0
PBRM1	55193	broad.mit.edu	37	3	52643617	52643617	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:52643617C>T	uc003des.2	-	16	2291	c.2279G>A	c.(2278-2280)CGC>CAC	p.R760H	PBRM1_uc003dex.2_RNA|PBRM1_uc003deq.2_Missense_Mutation_p.R760H|PBRM1_uc003der.2_Missense_Mutation_p.R728H|PBRM1_uc003det.2_Missense_Mutation_p.R775H|PBRM1_uc003deu.2_Missense_Mutation_p.R775H|PBRM1_uc003dev.2_RNA|PBRM1_uc003dew.2_Missense_Mutation_p.R760H|PBRM1_uc010hmk.1_Missense_Mutation_p.R760H|PBRM1_uc003dey.2_Missense_Mutation_p.R760H|PBRM1_uc003dez.1_Missense_Mutation_p.R760H|PBRM1_uc003dfb.1_Missense_Mutation_p.R673H|PBRM1_uc003dfa.1_Missense_Mutation_p.R106H|PBRM1_uc003dfc.2_Missense_Mutation_p.R127H	NM_181042	NP_060635	Q86U86	PB1_HUMAN	polybromo 1 isoform 4	760					chromatin remodeling|mitosis|negative regulation of cell proliferation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nuclear chromosome	chromatin binding|DNA binding|protein binding			kidney(136)|breast(4)	140				BRCA - Breast invasive adenocarcinoma(193;1.8e-05)|Kidney(197;0.00105)|KIRC - Kidney renal clear cell carcinoma(197;0.00122)|OV - Ovarian serous cystadenocarcinoma(275;0.0613)		CAGGTCTCTGCGTGTTTCAAG	0.423			Mis|N|F|S|D|O		clear cell renal carcinoma|breast								19	124					0	0	0	0
MYH15	22989	broad.mit.edu	37	3	108147437	108147437	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:108147437G>A	uc003dxa.1	-	28	3721	c.3664C>T	c.(3664-3666)CTA>TTA	p.L1222L		NM_014981	NP_055796	Q9Y2K3	MYH15_HUMAN	myosin, heavy polypeptide 15	1222	Potential.					myofibril|myosin filament	actin binding|ATP binding|calmodulin binding|motor activity			ovary(5)|central_nervous_system(2)	7						ACCTGCTGTAGATTTTCTACC	0.488													16	213					0	0	0	0
SLC9A10	285335	broad.mit.edu	37	3	111981806	111981806	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:111981806C>T	uc003dyu.2	-	10	1384	c.1162G>A	c.(1162-1164)GAT>AAT	p.D388N	SLC9A10_uc011bhu.1_Intron|SLC9A10_uc010hqc.2_Missense_Mutation_p.D340N	NM_183061	NP_898884	Q4G0N8	S9A10_HUMAN	sperm-specific sodium proton exchanger	388					cell differentiation|multicellular organismal development|sodium ion transport|spermatogenesis	cilium|flagellar membrane|integral to membrane	solute:hydrogen antiporter activity			ovary(3)|breast(2)	5						AAATAAAGATCAGAGTAGGCA	0.333													7	68					0	0	0	0
RHO	6010	broad.mit.edu	37	3	129251462	129251462	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:129251462C>G	uc003emt.2	+	4	878	c.783C>G	c.(781-783)TTC>TTG	p.F261L		NM_000539	NP_000530	P08100	OPSD_HUMAN	rhodopsin	261	Helical; Name=6; (Potential).				protein-chromophore linkage|rhodopsin mediated signaling pathway	Golgi apparatus|integral to plasma membrane|photoreceptor inner segment membrane|photoreceptor outer segment membrane	G-protein coupled receptor activity|metal ion binding|photoreceptor activity|protein binding				0		all_neural(597;0.0227)|Myeloproliferative disorder(1037;0.0255)|Prostate(884;0.183)		GBM - Glioblastoma multiforme(114;2.58e-05)|Lung(219;0.0234)	Halothane(DB01159)	TCATCGCTTTCCTGATCTGCT	0.592													7	109					0	0	0	0
IGSF10	285313	broad.mit.edu	37	3	151164902	151164903	+	Missense_Mutation	DNP	GT	TC	TC			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:151164902_151164903GT>TC	uc011bod.1	-	4	2866_2867	c.2866_2867AC>GA	c.(2866-2868)ACA>GAA	p.T956E		NM_178822	NP_849144	Q6WRI0	IGS10_HUMAN	immunoglobulin superfamily, member 10 precursor	956					cell differentiation|multicellular organismal development|ossification	extracellular region				skin(7)|ovary(5)|central_nervous_system(1)	13			LUSC - Lung squamous cell carcinoma(72;0.0394)|Lung(72;0.0517)			TCTTACAGATGTCTGATGACTA	0.396													112	260					0	0	0	0
GOLIM4	27333	broad.mit.edu	37	3	167742808	167742808	+	Nonsense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:167742808G>A	uc003ffe.2	-	13	2043	c.1699C>T	c.(1699-1701)CAA>TAA	p.Q567*	GOLIM4_uc011bpe.1_Nonsense_Mutation_p.Q568*|GOLIM4_uc011bpf.1_Nonsense_Mutation_p.Q540*|GOLIM4_uc011bpg.1_Nonsense_Mutation_p.Q539*	NM_014498	NP_055313	O00461	GOLI4_HUMAN	golgi integral membrane protein 4	567	Glu-rich.|Lumenal (Potential).				transport	cis-Golgi network|endocytic vesicle|endosome membrane|Golgi cisterna membrane|Golgi lumen|integral to membrane|nucleus				breast(4)|skin(1)	5						TCTCTCACTTGCTCGGCTTCT	0.373													29	269					0	0	0	0
PSMD2	5708	broad.mit.edu	37	3	184023708	184023708	+	Silent	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:184023708C>G	uc003fnn.1	+	13	1725	c.1692C>G	c.(1690-1692)CTC>CTG	p.L564L	PSMD2_uc011brj.1_Silent_p.L405L|PSMD2_uc011brk.1_Silent_p.L434L	NM_002808	NP_002799	Q13200	PSMD2_HUMAN	proteasome 26S non-ATPase subunit 2	564	PC 5.				anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle|mRNA metabolic process|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|regulation of apoptosis|regulation of cellular amino acid metabolic process|regulation of protein catabolic process|S phase of mitotic cell cycle|viral reproduction	proteasome regulatory particle	enzyme regulator activity|protein binding				0	all_cancers(143;1.54e-10)|Ovarian(172;0.0339)		Epithelial(37;1.53e-33)|OV - Ovarian serous cystadenocarcinoma(80;2.72e-22)		Bortezomib(DB00188)	GACTGGGTCTCAACCACCTGG	0.493											OREG0015947	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	6	132					0	0	0	0
WDR53	348793	broad.mit.edu	37	3	196281368	196281368	+	Missense_Mutation	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:196281368T>C	uc003fwt.2	-	4	1262	c.791A>G	c.(790-792)AAG>AGG	p.K264R		NM_182627	NP_872433	Q7Z5U6	WDR53_HUMAN	WD repeat domain 53	264	WD 5.									breast(1)|skin(1)	2	all_cancers(143;8.88e-09)|Ovarian(172;0.0634)|Breast(254;0.135)		Epithelial(36;1.6e-23)|all cancers(36;1.54e-21)|OV - Ovarian serous cystadenocarcinoma(49;1.29e-18)|LUSC - Lung squamous cell carcinoma(58;1.51e-06)|Lung(62;1.95e-06)	GBM - Glioblastoma multiforme(46;0.00326)		CAACGTGATCTTCCCATCATT	0.468													19	220					0	0	0	0
UGT2B10	7365	broad.mit.edu	37	4	69884067	69884067	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr4:69884067C>G	uc011cao.1	-	5	782	c.646G>C	c.(646-648)GAC>CAC	p.D216H	UGT2B10_uc011can.1_Missense_Mutation_p.D132H			P36537	UDB10_HUMAN	RecName: Full=UDP-glucuronosyltransferase 2B28;          Short=UDPGT 2B28;          EC=2.4.1.17; Flags: Precursor;	253					lipid metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	glucuronosyltransferase activity			skin(3)|ovary(2)	5						AGCCATATGTCAGCTTTTCCC	0.363													33	256					0	0	0	0
CDS1	1040	broad.mit.edu	37	4	85538789	85538789	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr4:85538789C>T	uc011ccv.1	+	4	913	c.415C>T	c.(415-417)CTA>TTA	p.L139L		NM_001263	NP_001254	Q92903	CDS1_HUMAN	CDP-diacylglycerol synthase 1	139					signal transduction|visual perception	endoplasmic reticulum membrane|integral to membrane	diacylglycerol cholinephosphotransferase activity|phosphatidate cytidylyltransferase activity			large_intestine(2)|ovary(1)|breast(1)	4		Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.00101)		TTCTTATGATCTACCATGGTT	0.338													7	113					0	0	0	0
ADH5	128	broad.mit.edu	37	4	100003182	100003182	+	Missense_Mutation	SNP	T	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr4:100003182T>C	uc003hui.2	-	3	280	c.200A>G	c.(199-201)CAT>CGT	p.H67R	ADH5_uc003huk.1_Missense_Mutation_p.H67R|ADH5_uc003huj.2_5'UTR	NM_000671	NP_000662	P11766	ADHX_HUMAN	class III alcohol dehydrogenase, chi subunit	67		Zinc 1; catalytic.			ethanol oxidation|response to redox state		alcohol dehydrogenase (NAD) activity|electron carrier activity|fatty acid binding|formaldehyde dehydrogenase activity|S-(hydroxymethyl)glutathione dehydrogenase activity|zinc ion binding			ovary(1)	1				OV - Ovarian serous cystadenocarcinoma(123;2.5e-07)	NADH(DB00157)	AGCACCTTCATGTCCCAAGAT	0.453													15	74					0	0	0	0
TMEM184C	55751	broad.mit.edu	37	4	148539207	148539207	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr4:148539207G>A	uc003ila.3	+	1	669	c.100G>A	c.(100-102)GTG>ATG	p.V34M		NM_018241	NP_060711	Q9NVA4	T184C_HUMAN	transmembrane protein 184C	34	Helical; (Potential).					integral to membrane					0						TCCCCTATGCGTGTGGGAATT	0.502											OREG0016353	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	14	278					0	0	0	0
CLCN3	1182	broad.mit.edu	37	4	170628124	170628124	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr4:170628124G>T	uc003isi.2	+	11	2365	c.1856G>T	c.(1855-1857)TGG>TTG	p.W619L	CLCN3_uc003ish.2_Missense_Mutation_p.W619L|CLCN3_uc011cjz.1_Missense_Mutation_p.W602L|CLCN3_uc011cka.1_Missense_Mutation_p.W592L|CLCN3_uc003isj.1_Missense_Mutation_p.W592L	NM_001829	NP_001820	P51790	CLCN3_HUMAN	chloride channel 3 isoform b	619	Helical; (By similarity).				endosomal lumen acidification	cell surface|early endosome membrane|Golgi membrane|integral to membrane|late endosome membrane|transport vesicle membrane	antiporter activity|ATP binding|PDZ domain binding|protein heterodimerization activity|protein homodimerization activity|voltage-gated chloride channel activity			breast(2)|ovary(1)	3		Prostate(90;0.00601)|Renal(120;0.0183)		GBM - Glioblastoma multiforme(119;0.0233)|LUSC - Lung squamous cell carcinoma(193;0.131)		ACCAGTAAATGGGTTGGAGAT	0.438													6	130					1.12685e-05	1.27015e-05	1	0
SPCS3	60559	broad.mit.edu	37	4	177249416	177249416	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr4:177249416G>T	uc003iur.3	+	5	616	c.478G>T	c.(478-480)GTG>TTG	p.V160L		NM_021928	NP_068747	P61009	SPCS3_HUMAN	signal peptidase complex subunit 3	160	Lumenal (Potential).				energy reserve metabolic process|regulation of insulin secretion|signal peptide processing	integral to membrane|microsome|signal peptidase complex	peptidase activity			ovary(1)	1		Breast(14;0.0011)|Prostate(90;0.0129)|Melanoma(52;0.0133)|Renal(120;0.0376)|all_hematologic(60;0.124)		all cancers(43;2.43e-19)|Epithelial(43;1.84e-16)|OV - Ovarian serous cystadenocarcinoma(60;4.51e-09)|GBM - Glioblastoma multiforme(59;0.000142)|STAD - Stomach adenocarcinoma(60;0.00279)|LUSC - Lung squamous cell carcinoma(193;0.0319)		TCTACCTCTTGTGACAGGATC	0.348													13	90					1.5842e-08	1.86096e-08	1	0
HEATR7B2	133558	broad.mit.edu	37	5	41009477	41009477	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr5:41009477C>T	uc003jmj.3	-	32	3815	c.3325G>A	c.(3325-3327)GAA>AAA	p.E1109K	HEATR7B2_uc003jmi.3_Missense_Mutation_p.E664K	NM_173489	NP_775760	Q7Z745	HTRB2_HUMAN	HEAT repeat family member 7B2	1109							binding			ovary(6)|central_nervous_system(2)	8						GCTGGCTTTTCAGCCAGCGCC	0.498													11	114					0	0	0	0
HTR1A	3350	broad.mit.edu	37	5	63257049	63257049	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr5:63257049G>A	uc011cqt.1	-	1	498	c.498C>T	c.(496-498)CTC>CTT	p.L166L		NM_000524	NP_000515	P08908	5HT1A_HUMAN	5-hydroxytryptamine (serotonin) receptor 1A	166	Helical; Name=4; (By similarity).				behavior|positive regulation of cell proliferation	integral to plasma membrane	serotonin receptor activity			ovary(2)|pancreas(2)	4		Lung NSC(810;3.55e-06)|Prostate(74;0.0352)|Ovarian(174;0.0545)|Breast(144;0.0575)|Colorectal(97;0.234)		Lung(70;0.105)	Alprenolol(DB00866)|Aripiprazole(DB01238)|Buspirone(DB00490)|Clozapine(DB00363)|Eletriptan(DB00216)|Ergoloid mesylate(DB01049)|Fluvoxamine(DB00176)|Lisuride(DB00589)|Methysergide(DB00247)|Mirtazapine(DB00370)|Pindolol(DB00960)|Propranolol(DB00571)|Quetiapine(DB01224)|Sertraline(DB01104)|Tegaserod(DB01079)|Trazodone(DB00656)|Venlafaxine(DB00285)|Ziprasidone(DB00246)	GGATAGAGATGAGGAAGCCAA	0.607													8	99					0	0	0	0
EBF1	1879	broad.mit.edu	37	5	158223429	158223429	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr5:158223429G>A	uc010jip.2	-	9	1135	c.833C>T	c.(832-834)GCG>GTG	p.A278V	EBF1_uc011ddw.1_Missense_Mutation_p.A146V|EBF1_uc011ddx.1_Missense_Mutation_p.A279V|EBF1_uc003lxl.3_Missense_Mutation_p.A247V	NM_024007	NP_076870	Q9UH73	COE1_HUMAN	early B-cell factor	278	IPT/TIG.				multicellular organismal development	nucleus	DNA binding|metal ion binding		HMGA2/EBF1(2)	soft_tissue(2)|ovary(1)|central_nervous_system(1)|pancreas(1)	5	Renal(175;0.00196)	Acute lymphoblastic leukemia(3;2.99e-06)|all_hematologic(3;0.000772)|Medulloblastoma(196;0.037)|all_neural(177;0.143)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)			GATCACAGTCGCACCTCCCGT	0.463			T	HMGA2	lipoma								8	89					0	0	0	0
FLT4	2324	broad.mit.edu	37	5	180048861	180048861	+	Missense_Mutation	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr5:180048861C>A	uc003mma.3	-	13	1780	c.1701G>T	c.(1699-1701)GAG>GAT	p.E567D	FLT4_uc003mlz.3_Missense_Mutation_p.E567D|FLT4_uc003mmb.1_Missense_Mutation_p.E100D|FLT4_uc011dgy.1_Missense_Mutation_p.E567D	NM_002020	NP_002011	P35916	VGFR3_HUMAN	fms-related tyrosine kinase 4 isoform 2	567	Ig-like C2-type 6.|Extracellular (Potential).				positive regulation of cell proliferation	integral to plasma membrane	ATP binding|protein phosphatase binding|vascular endothelial growth factor receptor activity			lung(7)|skin(2)|ovary(2)|stomach(1)|central_nervous_system(1)|breast(1)|kidney(1)	15	all_cancers(89;2.21e-05)|all_epithelial(37;5.29e-06)|Renal(175;0.000159)|Lung NSC(126;0.00199)|all_lung(126;0.00351)|Breast(19;0.114)	all_cancers(40;0.00245)|Medulloblastoma(196;0.0133)|all_neural(177;0.0199)|all_hematologic(541;0.163)|Ovarian(839;0.238)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)	all cancers(165;0.134)	Sorafenib(DB00398)|Sunitinib(DB01268)	CCTCTAGTAGCTCCTCGGATG	0.622									Congenital_Hereditary_Lymphedema				11	97					0.00010058	0.000112075	1	0
DST	667	broad.mit.edu	37	6	56504792	56504792	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:56504792G>T	uc003pdf.2	-	18	2483	c.2455C>A	c.(2455-2457)CAT>AAT	p.H819N	DST_uc003pcz.3_Missense_Mutation_p.H641N|DST_uc011dxj.1_Missense_Mutation_p.H670N|DST_uc011dxk.1_Missense_Mutation_p.H681N|DST_uc011dxl.1_Missense_Mutation_p.H670N|DST_uc003pcy.3_Missense_Mutation_p.H315N|DST_uc003pdb.2_Missense_Mutation_p.H315N|DST_uc003pdc.3_Missense_Mutation_p.H315N|DST_uc003pdd.3_Missense_Mutation_p.H315N|DST_uc003pde.2_Missense_Mutation_p.H757N	NM_001144769	NP_001138241	Q03001	DYST_HUMAN	dystonin isoform 2	641					cell adhesion|cell cycle arrest|cell motility|hemidesmosome assembly|integrin-mediated signaling pathway|intermediate filament cytoskeleton organization|maintenance of cell polarity|microtubule cytoskeleton organization|response to wounding	actin cytoskeleton|axon|axon part|basement membrane|cell cortex|cell leading edge|cytoplasmic membrane-bounded vesicle|endoplasmic reticulum membrane|hemidesmosome|hemidesmosome|integral to membrane|intermediate filament|intermediate filament cytoskeleton|microtubule cytoskeleton|microtubule plus end|nuclear envelope|sarcomere|Z disc	actin binding|calcium ion binding|integrin binding|microtubule plus-end binding|protein binding|protein C-terminus binding|protein homodimerization activity			ovary(7)|central_nervous_system(6)|upper_aerodigestive_tract(1)	14	Lung NSC(77;0.103)		LUSC - Lung squamous cell carcinoma(124;0.0485)|Lung(124;0.0956)			ACATTTTTATGATTTTCTAAA	0.308													7	116					0.000157383	0.000173388	1	0
DST	667	broad.mit.edu	37	6	56505116	56505116	+	Nonsense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:56505116G>C	uc003pdf.2	-	17	2244	c.2216C>G	c.(2215-2217)TCA>TGA	p.S739*	DST_uc003pcz.3_Nonsense_Mutation_p.S561*|DST_uc011dxj.1_Nonsense_Mutation_p.S590*|DST_uc011dxk.1_Nonsense_Mutation_p.S601*|DST_uc011dxl.1_Nonsense_Mutation_p.S590*|DST_uc003pcy.3_Nonsense_Mutation_p.S235*|DST_uc003pdb.2_Nonsense_Mutation_p.S235*|DST_uc003pdc.3_Nonsense_Mutation_p.S235*|DST_uc003pdd.3_Nonsense_Mutation_p.S235*|DST_uc003pde.2_Nonsense_Mutation_p.S677*	NM_001144769	NP_001138241	Q03001	DYST_HUMAN	dystonin isoform 2	561					cell adhesion|cell cycle arrest|cell motility|hemidesmosome assembly|integrin-mediated signaling pathway|intermediate filament cytoskeleton organization|maintenance of cell polarity|microtubule cytoskeleton organization|response to wounding	actin cytoskeleton|axon|axon part|basement membrane|cell cortex|cell leading edge|cytoplasmic membrane-bounded vesicle|endoplasmic reticulum membrane|hemidesmosome|hemidesmosome|integral to membrane|intermediate filament|intermediate filament cytoskeleton|microtubule cytoskeleton|microtubule plus end|nuclear envelope|sarcomere|Z disc	actin binding|calcium ion binding|integrin binding|microtubule plus-end binding|protein binding|protein C-terminus binding|protein homodimerization activity			ovary(7)|central_nervous_system(6)|upper_aerodigestive_tract(1)	14	Lung NSC(77;0.103)		LUSC - Lung squamous cell carcinoma(124;0.0485)|Lung(124;0.0956)			AACTAATCCTGATGGGAAACC	0.453													9	140					0	0	0	0
DST	667	broad.mit.edu	37	6	56505121	56505121	+	Missense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:56505121G>T	uc003pdf.2	-	17	2239	c.2211C>A	c.(2209-2211)TTC>TTA	p.F737L	DST_uc003pcz.3_Missense_Mutation_p.F559L|DST_uc011dxj.1_Missense_Mutation_p.F588L|DST_uc011dxk.1_Missense_Mutation_p.F599L|DST_uc011dxl.1_Missense_Mutation_p.F588L|DST_uc003pcy.3_Missense_Mutation_p.F233L|DST_uc003pdb.2_Missense_Mutation_p.F233L|DST_uc003pdc.3_Missense_Mutation_p.F233L|DST_uc003pdd.3_Missense_Mutation_p.F233L|DST_uc003pde.2_Missense_Mutation_p.F675L	NM_001144769	NP_001138241	Q03001	DYST_HUMAN	dystonin isoform 2	559					cell adhesion|cell cycle arrest|cell motility|hemidesmosome assembly|integrin-mediated signaling pathway|intermediate filament cytoskeleton organization|maintenance of cell polarity|microtubule cytoskeleton organization|response to wounding	actin cytoskeleton|axon|axon part|basement membrane|cell cortex|cell leading edge|cytoplasmic membrane-bounded vesicle|endoplasmic reticulum membrane|hemidesmosome|hemidesmosome|integral to membrane|intermediate filament|intermediate filament cytoskeleton|microtubule cytoskeleton|microtubule plus end|nuclear envelope|sarcomere|Z disc	actin binding|calcium ion binding|integrin binding|microtubule plus-end binding|protein binding|protein C-terminus binding|protein homodimerization activity			ovary(7)|central_nervous_system(6)|upper_aerodigestive_tract(1)	14	Lung NSC(77;0.103)		LUSC - Lung squamous cell carcinoma(124;0.0485)|Lung(124;0.0956)			ATCCTGATGGGAAACCAGGTG	0.443													11	141					2.61681e-11	3.14987e-11	1	0
DST	667	broad.mit.edu	37	6	56505218	56505218	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:56505218G>A	uc003pdf.2	-	17	2142	c.2114C>T	c.(2113-2115)ACA>ATA	p.T705I	DST_uc003pcz.3_Missense_Mutation_p.T527I|DST_uc011dxj.1_Missense_Mutation_p.T556I|DST_uc011dxk.1_Missense_Mutation_p.T567I|DST_uc011dxl.1_Missense_Mutation_p.T556I|DST_uc003pcy.3_Missense_Mutation_p.T201I|DST_uc003pdb.2_Missense_Mutation_p.T201I|DST_uc003pdc.3_Missense_Mutation_p.T201I|DST_uc003pdd.3_Missense_Mutation_p.T201I|DST_uc003pde.2_Missense_Mutation_p.T643I	NM_001144769	NP_001138241	Q03001	DYST_HUMAN	dystonin isoform 2	527					cell adhesion|cell cycle arrest|cell motility|hemidesmosome assembly|integrin-mediated signaling pathway|intermediate filament cytoskeleton organization|maintenance of cell polarity|microtubule cytoskeleton organization|response to wounding	actin cytoskeleton|axon|axon part|basement membrane|cell cortex|cell leading edge|cytoplasmic membrane-bounded vesicle|endoplasmic reticulum membrane|hemidesmosome|hemidesmosome|integral to membrane|intermediate filament|intermediate filament cytoskeleton|microtubule cytoskeleton|microtubule plus end|nuclear envelope|sarcomere|Z disc	actin binding|calcium ion binding|integrin binding|microtubule plus-end binding|protein binding|protein C-terminus binding|protein homodimerization activity			ovary(7)|central_nervous_system(6)|upper_aerodigestive_tract(1)	14	Lung NSC(77;0.103)		LUSC - Lung squamous cell carcinoma(124;0.0485)|Lung(124;0.0956)			TAGGGAAGGTGTTAAACTCTG	0.478													14	169					0	0	0	0
RSPH4A	345895	broad.mit.edu	37	6	116949382	116949382	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:116949382G>C	uc003pxe.2	+	3	1657	c.1512G>C	c.(1510-1512)CAG>CAC	p.Q504H	RSPH4A_uc010kee.2_Missense_Mutation_p.Q504H	NM_001010892	NP_001010892	Q5TD94	RSH4A_HUMAN	radial spoke head 4 homolog A isoform 1	504					cilium axoneme assembly|cilium movement	cytoplasm|cytoskeleton|radial spoke					0						GATTTTATCAGTTTGGTGAAG	0.453									Kartagener_syndrome				12	136					0	0	0	0
SASH1	23328	broad.mit.edu	37	6	148865488	148865488	+	Missense_Mutation	SNP	A	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:148865488A>G	uc003qme.1	+	18	3357	c.2882A>G	c.(2881-2883)CAC>CGC	p.H961R	SASH1_uc011eeb.1_Missense_Mutation_p.H722R|SASH1_uc003qmf.1_Missense_Mutation_p.H371R	NM_015278	NP_056093	O94885	SASH1_HUMAN	SAM and SH3 domain containing 1	961							protein binding			central_nervous_system(1)	1		Ovarian(120;0.0169)		OV - Ovarian serous cystadenocarcinoma(155;5.63e-11)|GBM - Glioblastoma multiforme(68;0.0701)		GAAGGAACACACCATCCCCTG	0.522													8	133					0	0	0	0
SYNE1	23345	broad.mit.edu	37	6	152469388	152469388	+	Silent	SNP	A	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:152469388A>G	uc010kiw.2	-	137	25370	c.24768T>C	c.(24766-24768)AAT>AAC	p.N8256N	SYNE1_uc010kiv.2_Silent_p.N2780N|SYNE1_uc003qos.3_Silent_p.N2780N|SYNE1_uc003qot.3_Silent_p.N8185N|SYNE1_uc003qou.3_Silent_p.N8256N|SYNE1_uc003qop.3_Silent_p.N418N|SYNE1_uc011eez.1_Silent_p.N458N|SYNE1_uc003qoq.3_Silent_p.N458N|SYNE1_uc003qor.3_Silent_p.N1156N	NM_182961	NP_892006	Q8NF91	SYNE1_HUMAN	spectrin repeat containing, nuclear envelope 1	8256	Cytoplasmic (Potential).				cell death|cytoskeletal anchoring at nuclear membrane|Golgi organization|muscle cell differentiation|nuclear matrix anchoring at nuclear membrane	cytoskeleton|Golgi apparatus|integral to membrane|nuclear outer membrane|postsynaptic membrane|sarcomere|SUN-KASH complex	actin binding|lamin binding			central_nervous_system(15)|upper_aerodigestive_tract(9)|ovary(8)|skin(6)|large_intestine(5)|pancreas(2)	45		Ovarian(120;0.0955)	BRCA - Breast invasive adenocarcinoma(37;0.243)	OV - Ovarian serous cystadenocarcinoma(155;2.24e-10)		AGAGGGAGAGATTGGAGGAAG	0.632										HNSCC(10;0.0054)			6	85					0	0	0	0
C6orf118	168090	broad.mit.edu	37	6	165715310	165715310	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:165715310G>A	uc003qum.3	-	2	537	c.501C>T	c.(499-501)GGC>GGT	p.G167G	C6orf118_uc011egi.1_RNA	NM_144980	NP_659417	Q5T5N4	CF118_HUMAN	hypothetical protein LOC168090	167											0		Breast(66;6.27e-05)|Ovarian(120;0.0228)|Prostate(117;0.0906)|all_neural(5;0.157)		OV - Ovarian serous cystadenocarcinoma(33;3.23e-18)|BRCA - Breast invasive adenocarcinoma(81;3.11e-06)|GBM - Glioblastoma multiforme(31;0.000313)		ATCCAGGAGGGCCCCGTCCAG	0.627													8	156					0	0	0	0
DAGLB	221955	broad.mit.edu	37	7	6449640	6449640	+	Missense_Mutation	SNP	T	C	C	rs138947170		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:6449640T>C	uc003sqa.2	-	15	2017	c.1847A>G	c.(1846-1848)TAT>TGT	p.Y616C	DAGLB_uc003spy.2_Missense_Mutation_p.Y162C|DAGLB_uc003spz.2_Missense_Mutation_p.Y313C|DAGLB_uc011jwt.1_Missense_Mutation_p.Y430C|DAGLB_uc011jwu.1_Missense_Mutation_p.Y487C|DAGLB_uc003sqb.2_Missense_Mutation_p.Y335C|DAGLB_uc003sqc.2_Missense_Mutation_p.Y335C|DAGLB_uc011jwv.1_RNA|DAGLB_uc003sqd.3_Missense_Mutation_p.Y575C	NM_139179	NP_631918	Q8NCG7	DGLB_HUMAN	diacylglycerol lipase, beta isoform 1	616	Cytoplasmic (Potential).				lipid catabolic process|platelet activation	integral to membrane|plasma membrane	acylglycerol lipase activity|metal ion binding|triglyceride lipase activity			ovary(2)|central_nervous_system(1)	3		Ovarian(82;0.232)		UCEC - Uterine corpus endometrioid carcinoma (126;0.102)		CTTGGCGCTATAGTGAGCAGC	0.597													7	100					0	0	0	0
BMPER	168667	broad.mit.edu	37	7	34097738	34097738	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:34097738G>A	uc011kap.1	+	10	1109	c.995G>A	c.(994-996)CGC>CAC	p.R332H		NM_133468	NP_597725	Q8N8U9	BMPER_HUMAN	BMP-binding endothelial regulator precursor	332	VWFC 5.				blood vessel endothelial cell proliferation involved in sprouting angiogenesis|endothelial cell activation|negative regulation of BMP signaling pathway|positive regulation of ERK1 and ERK2 cascade|regulation of endothelial cell migration|regulation of pathway-restricted SMAD protein phosphorylation	extracellular space				ovary(2)|central_nervous_system(1)	3						ACGGAGTGTCGCAATAAGCAG	0.493													8	86					0	0	0	0
ZNF117	51351	broad.mit.edu	37	7	64453119	64453119	+	5'Flank	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:64453119C>A	uc003ttr.2	-						ZNF117_uc011kdr.1_Missense_Mutation_p.V93F	NM_015852	NP_056936	Q03924	ZN117_HUMAN	zinc finger protein 117							nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			skin(1)	1		Lung NSC(55;0.0295)|all_lung(88;0.0691)				tttgacccgacatgaatttca	0													6	60					8.12818e-05	9.10917e-05	1	0
KIAA1549	57670	broad.mit.edu	37	7	138602370	138602370	+	Missense_Mutation	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:138602370C>T	uc011kql.1	-	2	2051	c.2002G>A	c.(2002-2004)GAG>AAG	p.E668K	KIAA1549_uc003vuk.3_Missense_Mutation_p.E618K|KIAA1549_uc011kqj.1_Missense_Mutation_p.E668K	NM_020910	NP_065961	Q9HCM3	K1549_HUMAN	hypothetical protein LOC57670 isoform 1	668	Ser-rich.					integral to membrane			KIAA1549/BRAF(229)	central_nervous_system(229)|pancreas(1)	230						GTAAATGTCTCAACCAAGGGA	0.502			O	BRAF	pilocytic astrocytoma								3	24					0	0	0	0
DNAJB6	10049	broad.mit.edu	37	7	157160131	157160131	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:157160131C>T	uc003wnk.2	+	5	454	c.300C>T	c.(298-300)TTC>TTT	p.F100F	DNAJB6_uc003wnj.2_Silent_p.F100F|DNAJB6_uc003wnl.2_Silent_p.F87F|DNAJB6_uc011kvy.1_Silent_p.F51F|DNAJB6_uc011kvz.1_Silent_p.F100F|DNAJB6_uc010lqt.2_Silent_p.F100F	NM_058246	NP_490647	O75190	DNJB6_HUMAN	DnaJ (Hsp40) homolog, subfamily B, member 6	100	Gly/Phe-rich.|Interaction with HSP70.				intermediate filament organization|negative regulation of caspase activity|protein folding|response to unfolded protein	nucleus|perinuclear region of cytoplasm	ATPase activator activity|chaperone binding|heat shock protein binding|unfolded protein binding			ovary(2)	2	all_neural(206;0.181)	all_epithelial(9;0.000606)|all_hematologic(28;0.00287)|Acute lymphoblastic leukemia(9;0.0647)|Ovarian(593;0.196)	OV - Ovarian serous cystadenocarcinoma(82;0.00399)	UCEC - Uterine corpus endometrioid carcinoma (81;0.172)		ATGATGTCTTCAGGGAATTTT	0.408													18	242					0	0	0	0
CYP7A1	1581	broad.mit.edu	37	8	59409510	59409510	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:59409510G>A	uc003xtm.3	-	3	624	c.561C>T	c.(559-561)ATC>ATT	p.I187I		NM_000780	NP_000771	P22680	CP7A1_HUMAN	cytochrome P450, family 7, subfamily A,	187					bile acid biosynthetic process|cellular lipid metabolic process|cellular response to cholesterol|cellular response to glucose stimulus|cholesterol catabolic process|cholesterol homeostasis|regulation of bile acid biosynthetic process|xenobiotic metabolic process	endoplasmic reticulum membrane|microsome	cholesterol 7-alpha-monooxygenase activity|electron carrier activity|heme binding			ovary(1)	1		all_lung(136;0.0271)|Lung NSC(129;0.0351)|all_epithelial(80;0.0554)				CTCTGCCAAAGATAGTTAAAT	0.453									Neonatal_Giant_Cell_Hepatitis				28	218					0	0	0	0
PREX2	80243	broad.mit.edu	37	8	69021852	69021852	+	Missense_Mutation	SNP	T	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:69021852T>G	uc003xxv.1	+	25	3167	c.3140T>G	c.(3139-3141)ATA>AGA	p.I1047R	PREX2_uc011lez.1_Missense_Mutation_p.I982R	NM_024870	NP_079146	Q70Z35	PREX2_HUMAN	DEP domain containing 2 isoform a	1047					G-protein coupled receptor protein signaling pathway|intracellular signal transduction	intracellular	protein binding|Rac GTPase activator activity|Rac guanyl-nucleotide exchange factor activity			skin(6)|large_intestine(4)|pancreas(3)|lung(2)|ovary(1)|kidney(1)	17						GTTTGTCAAATAGATGAGTAA	0.348													34	99					0	0	0	0
FER1L6	654463	broad.mit.edu	37	8	125076788	125076788	+	Nonsense_Mutation	SNP	G	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:125076788G>T	uc003yqw.2	+	26	3735	c.3529G>T	c.(3529-3531)GAG>TAG	p.E1177*	uc003yqy.1_Intron	NM_001039112	NP_001034201	Q2WGJ9	FR1L6_HUMAN	fer-1-like 6	1177	Cytoplasmic (Potential).					integral to membrane				ovary(5)|skin(5)|central_nervous_system(1)	11	Lung NSC(37;4.1e-12)|Ovarian(258;0.00438)|all_neural(195;0.0741)		STAD - Stomach adenocarcinoma(47;0.00186)			TGTAGCCCAGGAGCCACCAAA	0.527													7	120					0.000274275	0.000298791	1	0
RNF139	11236	broad.mit.edu	37	8	125498931	125498931	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:125498931G>A	uc003yrc.2	+	2	1384	c.1041G>A	c.(1039-1041)GAG>GAA	p.E347E		NM_007218	NP_009149	Q8WU17	RN139_HUMAN	ring finger protein 139	347					negative regulation of cell proliferation|regulation of protein ubiquitination	endoplasmic reticulum membrane|integral to membrane	protein binding|receptor activity|ubiquitin-protein ligase activity|zinc ion binding			kidney(1)	1	Ovarian(258;0.00438)|all_neural(195;0.0779)|Hepatocellular(40;0.108)		STAD - Stomach adenocarcinoma(47;0.00288)			GACCAGAAGAGAGACTTATTC	0.413									Renal_Cell_Cancer_associated_with_constitutional_translocation_of_chromosome_3				50	350					0	0	0	0
ADCY8	114	broad.mit.edu	37	8	131880122	131880122	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:131880122G>A	uc003ytd.3	-	9	2436	c.2180C>T	c.(2179-2181)ACG>ATG	p.T727M	ADCY8_uc010mds.2_Intron	NM_001115	NP_001106	P40145	ADCY8_HUMAN	adenylate cyclase 8	727	Helical; (Potential).				activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity|activation of protein kinase A activity|cellular response to glucagon stimulus|energy reserve metabolic process|inhibition of adenylate cyclase activity by G-protein signaling pathway|nerve growth factor receptor signaling pathway|synaptic transmission|transmembrane transport|water transport	integral to membrane|membrane fraction|plasma membrane	ATP binding|calcium- and calmodulin-responsive adenylate cyclase activity|metal ion binding			skin(4)|large_intestine(1)|central_nervous_system(1)	6	Esophageal squamous(12;0.00693)|Ovarian(258;0.00707)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.000538)			TTGTATTGCCGTGATAAATAG	0.353										HNSCC(32;0.087)			18	113					0	0	0	0
OC90	729330	broad.mit.edu	37	8	133062085	133062085	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:133062085G>C	uc003ytg.2	-	1	32	c.32C>G	c.(31-33)ACA>AGA	p.T11R	OC90_uc011lix.1_Intron	NM_001080399	NP_001073868	Q02509	OC90_HUMAN	otoconin 90	Error:Variant_position_missing_in_Q02509_after_alignment					lipid catabolic process|phospholipid metabolic process		calcium ion binding|phospholipase A2 activity			ovary(2)|skin(1)	3	Esophageal squamous(12;0.00693)|Ovarian(258;0.00769)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.000805)			TGGCTGTAATGTATCACAGAT	0.408													8	162					0	0	0	0
FAM135B	51059	broad.mit.edu	37	8	139380208	139380208	+	Missense_Mutation	SNP	T	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:139380208T>G	uc003yuy.2	-	2	190	c.19A>C	c.(19-21)ACG>CCG	p.T7P	FAM135B_uc003yux.2_5'UTR|FAM135B_uc003yuz.2_RNA	NM_015912	NP_056996	Q49AJ0	F135B_HUMAN	hypothetical protein LOC51059	7										ovary(7)|skin(2)	9	all_epithelial(106;8.29e-14)|Lung NSC(106;6.88e-06)|all_lung(105;1.44e-05)|Ovarian(258;0.00672)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0805)			AACTCAACCGTTCCTTGTATT	0.323										HNSCC(54;0.14)			18	201					0	0	0	0
PTENP1	11191	broad.mit.edu	37	9	33675711	33675711	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr9:33675711C>G	uc003zth.3	-	1	1708	c.837G>C	c.(835-837)AAG>AAC	p.K279N		NR_023917				SubName: Full=Phosphatase and tensin homolog 2; Flags: Fragment;												0						CTAGATACTCCTTGTCATTAT	0.353													44	133					0	0	0	0
ZCCHC6	79670	broad.mit.edu	37	9	88940312	88940312	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr9:88940312G>A	uc004aoq.2	-	12	1941	c.1726C>T	c.(1726-1728)CGT>TGT	p.R576C	ZCCHC6_uc011ltf.1_RNA|ZCCHC6_uc004aor.2_RNA|ZCCHC6_uc004aos.2_RNA|ZCCHC6_uc004aot.2_Missense_Mutation_p.R453C|ZCCHC6_uc004aou.2_Missense_Mutation_p.R576C	NM_024617	NP_078893	Q5VYS8	TUT7_HUMAN	zinc finger, CCHC domain containing 6	576	PAP-associated 1.				RNA 3'-end processing		nucleic acid binding|RNA uridylyltransferase activity|zinc ion binding			ovary(2)	2						TCTTTGACACGAATACTTATC	0.423													4	137					0	0	0	0
C9orf47	286223	broad.mit.edu	37	9	91605992	91605992	+	Missense_Mutation	SNP	C	G	G			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr9:91605992C>G	uc004aqd.2	+	1	215	c.82C>G	c.(82-84)CGA>GGA	p.R28G	S1PR3_uc004aqe.2_5'Flank|C9orf47_uc004aqc.1_Missense_Mutation_p.R28G	NM_001001938	NP_001001938	Q6ZRZ4	CI047_HUMAN	hypothetical protein LOC286223 isoform 1	28						extracellular region					0						GCTGTCAGGGCGACAGGCGCC	0.567													7	50					0	0	0	0
PTCH1	5727	broad.mit.edu	37	9	98209663	98209663	+	Missense_Mutation	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr9:98209663G>A	uc004avk.3	-	23	4063	c.3875C>T	c.(3874-3876)TCC>TTC	p.S1292F	PTCH1_uc010mrn.2_Missense_Mutation_p.S84F|PTCH1_uc010mro.2_Missense_Mutation_p.S1141F|PTCH1_uc010mrp.2_Missense_Mutation_p.S1141F|PTCH1_uc010mrq.2_Missense_Mutation_p.S1141F|PTCH1_uc004avl.3_Missense_Mutation_p.S1141F|PTCH1_uc010mrr.2_Missense_Mutation_p.S1226F|PTCH1_uc004avm.3_Missense_Mutation_p.S1291F	NM_000264	NP_000255	Q13635	PTC1_HUMAN	patched isoform L	1292	Cytoplasmic (Potential).				embryonic limb morphogenesis|negative regulation of multicellular organism growth|protein processing|regulation of smoothened signaling pathway|smoothened signaling pathway	integral to plasma membrane	hedgehog receptor activity	p.S1292F(1)		skin(242)|central_nervous_system(72)|bone(33)|upper_aerodigestive_tract(11)|lung(6)|large_intestine(4)|breast(4)|oesophagus(3)|ovary(3)|vulva(1)	379		Medulloblastoma(1;7.87e-06)|all_neural(1;0.000555)|Acute lymphoblastic leukemia(62;0.136)				GGGAGGCAGGGACCCTGAGTC	0.652									Basal_Cell_Nevus_syndrome				15	184					0	0	0	0
CAMSAP1	157922	broad.mit.edu	37	9	138714638	138714638	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr9:138714638G>A	uc004cgr.3	-	11	1869	c.1869C>T	c.(1867-1869)ATC>ATT	p.I623I	CAMSAP1_uc004cgq.3_Silent_p.I513I|CAMSAP1_uc010nbg.2_Silent_p.I345I	NM_015447	NP_056262	Q5T5Y3	CAMP1_HUMAN	calmodulin regulated spectrin-associated protein	623						cytoplasm|microtubule				ovary(1)|central_nervous_system(1)|pancreas(1)	3				OV - Ovarian serous cystadenocarcinoma(145;1.4e-06)|Epithelial(140;1.11e-05)		TCCTAGACACGATGCTCCTCG	0.547													11	138					0	0	0	0
P2RY10	27334	broad.mit.edu	37	X	78217001	78217001	+	Silent	SNP	C	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chrX:78217001C>T	uc004ede.2	+	4	1353	c.984C>T	c.(982-984)CTC>CTT	p.L328L	P2RY10_uc004edf.2_Silent_p.L328L	NM_014499	NP_055314	O00398	P2Y10_HUMAN	G-protein coupled purinergic receptor P2Y10	328	Cytoplasmic (Potential).					integral to membrane|plasma membrane	purinergic nucleotide receptor activity, G-protein coupled			ovary(2)|lung(2)|breast(1)	5						GCTCCCGCCTCATGAGCAAGG	0.438													18	119					0	0	0	0
CLDN2	9075	broad.mit.edu	37	X	106171760	106171760	+	Missense_Mutation	SNP	G	C	C			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chrX:106171760G>C	uc004emq.1	+	2	821	c.302G>C	c.(301-303)GGC>GCC	p.G101A	MORC4_uc004emp.3_Intron|CLDN2_uc004emt.1_Missense_Mutation_p.G101A	NM_020384	NP_065117	P57739	CLD2_HUMAN	claudin 2	101	Helical; (Potential).				calcium-independent cell-cell adhesion	integral to membrane|tight junction	identical protein binding|structural molecule activity			ovary(1)	1						TCTGTGGTGGGCATGAGATGC	0.572													16	96					0	0	0	0
SLC25A5	292	broad.mit.edu	37	X	118604391	118604391	+	Silent	SNP	G	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chrX:118604391G>A	uc004erh.3	+	3	770	c.654G>A	c.(652-654)CAG>CAA	p.Q218Q	LOC100303728_uc004ere.1_5'Flank|LOC100303728_uc004erg.1_5'Flank	NM_001152	NP_001143	P05141	ADT2_HUMAN	adenine nucleotide translocator 2	218	Helical; Name=5; (By similarity).|Solcar 3.				chromosome segregation|energy reserve metabolic process|interspecies interaction between organisms|regulation of insulin secretion|viral reproduction	integral to plasma membrane|mitochondrial inner membrane|mitochondrial nucleoid|MMXD complex	adenine transmembrane transporter activity|protein binding			ovary(1)	1					Clodronate(DB00720)	TGATCGCACAGACTGTCACTG	0.488													15	72					0	0	0	0
AFF2	2334	broad.mit.edu	37	X	147743550	147743550	+	Missense_Mutation	SNP	C	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chrX:147743550C>A	uc004fcp.2	+	3	781	c.302C>A	c.(301-303)TCT>TAT	p.S101Y	AFF2_uc004fco.2_Missense_Mutation_p.S97Y|AFF2_uc004fcq.2_Missense_Mutation_p.S97Y|AFF2_uc004fcr.2_Missense_Mutation_p.S97Y|AFF2_uc011mxb.1_Missense_Mutation_p.S101Y|AFF2_uc004fcs.2_Missense_Mutation_p.S97Y	NM_002025	NP_002016	P51816	AFF2_HUMAN	fragile X mental retardation 2	101					brain development|mRNA processing|regulation of RNA splicing|RNA splicing	nuclear speck	G-quadruplex RNA binding|protein binding			ovary(3)|pancreas(2)	5	Acute lymphoblastic leukemia(192;6.56e-05)					CCAAAGAATTCTGTGCCCCAG	0.403													29	170					7.38237e-10	8.83167e-10	1	0
SLC2A5	6518	broad.mit.edu	37	1	9129568	9129568	+	Frame_Shift_Del	DEL	C	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:9129568delC	uc001apo.2	-	1	320	c.28delG	c.(28-30)GAAfs	p.E10fs	SLC2A5_uc010nzz.1_5'UTR|SLC2A5_uc010oaa.1_5'UTR|SLC2A5_uc010oab.1_Frame_Shift_Del_p.E10fs|SLC2A5_uc010oac.1_Frame_Shift_Del_p.E10fs|SLC2A5_uc001app.3_Frame_Shift_Del_p.E10fs	NM_003039	NP_003030	P22732	GTR5_HUMAN	solute carrier family 2 (facilitated	10	Cytoplasmic (Potential).				carbohydrate metabolic process	integral to membrane|plasma membrane	fructose transmembrane transporter activity|glucose transmembrane transporter activity			pancreas(2)|ovary(1)	3	Ovarian(185;0.112)|all_lung(157;0.185)	all_epithelial(116;1.34e-15)|all_lung(118;9.46e-05)|Lung NSC(185;0.000172)|Renal(390;0.000469)|Colorectal(325;0.0062)|Breast(348;0.00715)|Hepatocellular(190;0.0228)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.104)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;7.78e-07)|COAD - Colon adenocarcinoma(227;8.83e-05)|Kidney(185;0.000286)|KIRC - Kidney renal clear cell carcinoma(229;0.00103)|STAD - Stomach adenocarcinoma(132;0.0019)|BRCA - Breast invasive adenocarcinoma(304;0.00199)|READ - Rectum adenocarcinoma(331;0.0649)		CTCACCCCTTCCTTCATGCTC	0.587													---	---	---							
SOAT1	6646	broad.mit.edu	37	1	179310294	179310295	+	Frame_Shift_Ins	INS	-	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:179310294_179310295insT	uc001gml.2	+	7	692_693	c.629_630insT	c.(628-630)TATfs	p.Y210fs	SOAT1_uc010pni.1_Frame_Shift_Ins_p.Y145fs|SOAT1_uc001gmm.2_Frame_Shift_Ins_p.Y152fs|SOAT1_uc010pnj.1_5'UTR|SOAT1_uc010pnk.1_Frame_Shift_Ins_p.Y145fs	NM_003101	NP_003092	P35610	SOAT1_HUMAN	sterol O-acyltransferase 1	210					cholesterol efflux|cholesterol esterification|cholesterol homeostasis|cholesterol metabolic process|cholesterol storage|macrophage derived foam cell differentiation|positive regulation of amyloid precursor protein biosynthetic process|very-low-density lipoprotein particle assembly	endoplasmic reticulum membrane|integral to membrane|microsome	cholesterol binding|cholesterol O-acyltransferase activity|fatty-acyl-CoA binding			central_nervous_system(1)|skin(1)	2					Ezetimibe(DB00973)|Hesperetin(DB01094)	GCCACTGGCTATAGCAAGAGTT	0.431													---	---	---							
C1orf35	79169	broad.mit.edu	37	1	228288853	228288854	+	Frame_Shift_Ins	INS	-	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr1:228288853_228288854insT	uc001hrx.2	-	8	864_865	c.770_771insA	c.(769-771)CATfs	p.H257fs	C1orf35_uc009xew.2_RNA	NM_024319	NP_077295	Q9BU76	MMTA2_HUMAN	hypothetical protein LOC79169	257											0		Prostate(94;0.0488)				AGCCTCTGTCATGCCACCTGCG	0.634													---	---	---							
Unknown	0	broad.mit.edu	37	10	9557581	9557588	+	IGR	DEL	GGAAGGAA	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr10:9557581_9557588delGGAAGGAA								None (None upstream) : None (None downstream)																							gaggaaagagggaaggaaggaaggaagg	0.096													---	---	---							
Unknown	0	broad.mit.edu	37	10	42767227	42767228	+	IGR	INS	-	A	A	rs59441582		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr10:42767227_42767228insA								None (None upstream) : LOC441666 (60087 downstream)																							AATTTTTTTTTATTGTGTGCCC	0.337													---	---	---							
TTC17	55761	broad.mit.edu	37	11	43413095	43413096	+	Frame_Shift_Ins	INS	-	A	A	rs138517922	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:43413095_43413096insA	uc001mxi.2	+	4	514_515	c.500_501insA	c.(499-501)CCAfs	p.P167fs	TTC17_uc001mxh.2_Frame_Shift_Ins_p.P167fs|TTC17_uc010rfj.1_Frame_Shift_Ins_p.P110fs	NM_018259	NP_060729	Q96AE7	TTC17_HUMAN	tetratricopeptide repeat domain 17	167							binding			ovary(5)	5						CTAGAACTTCCATATAGTATAC	0.356													---	---	---							
Unknown	0	broad.mit.edu	37	11	45609521	45609528	+	IGR	DEL	AGAAAGAA	-	-	rs11038557		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:45609521_45609528delAGAAAGAA								SYT13 (301637 upstream) : CHST1 (60899 downstream)																							agaaagaaagagaaagaaagaaagaaag	0.000													---	---	---							
Unknown	0	broad.mit.edu	37	11	49104713	49104713	+	IGR	DEL	C	-	-	rs149147831		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr11:49104713delC								OR4A47 (593441 upstream) : FOLH1 (63475 downstream)																							tttcttCCTTCCCCCCGCAAA	0.428													---	---	---							
FAM186A	121006	broad.mit.edu	37	12	50791616	50791617	+	5'Flank	INS	-	TC	TC	rs146656977	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:50791616_50791617insTC	uc001rwl.2	-							NM_001145475	NP_001138947	A6NE01	F186A_HUMAN	family with sequence similarity 186, member A												0						ctttctttctttcttttttttt	0.005													---	---	---							
XPOT	11260	broad.mit.edu	37	12	64812755	64812755	+	Frame_Shift_Del	DEL	T	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:64812755delT	uc001ssb.2	+	6	796	c.370delT	c.(370-372)TTTfs	p.F124fs	XPOT_uc009zqm.1_Frame_Shift_Del_p.F34fs	NM_007235	NP_009166	O43592	XPOT_HUMAN	tRNA exportin	124	Necessary for interaction with Ran, nuclear localization and nuclear import.				intracellular protein transport|tRNA export from nucleus	cytoplasm|nucleoplasm	protein transporter activity|tRNA binding			ovary(2)	2				GBM - Glioblastoma multiforme(28;0.0404)		GTGGCCCAAGTTTTTTTTTGA	0.443													---	---	---							
NAV3	89795	broad.mit.edu	37	12	78224970	78224975	+	5'Flank	DEL	AGAGAC	-	-	rs72186592	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr12:78224970_78224975delAGAGAC	uc001syp.2	+						NAV3_uc001syo.2_5'Flank	NM_014903	NP_055718	Q8IVL0	NAV3_HUMAN	neuron navigator 3							nuclear outer membrane	ATP binding|nucleoside-triphosphatase activity			large_intestine(6)|ovary(5)|lung(2)|breast(1)|skin(1)|kidney(1)|pancreas(1)	17						agagagagagagagacagagagagag	0.204										HNSCC(70;0.22)			---	---	---							
Unknown	0	broad.mit.edu	37	13	64499691	64499692	+	IGR	DEL	TG	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr13:64499691_64499692delTG								OR7E156P (182990 upstream) : None (None downstream)																							agtgtgcgtatgtgtgtgtgtg	0.193													---	---	---							
SOX21	11166	broad.mit.edu	37	13	95364121	95364135	+	In_Frame_Del	DEL	GGCCTCGTCGATGAA	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr13:95364121_95364135delGGCCTCGTCGATGAA	uc001vma.2	-	1	255_269	c.169_183delTTCATCGACGAGGCC	c.(169-183)TTCATCGACGAGGCCdel	p.FIDEA57del	uc001vmb.1_5'Flank	NM_007084	NP_009015	Q9Y651	SOX21_HUMAN	SRY-box 21	57_61	HMG box.				regulation of transcription from RNA polymerase II promoter|stem cell differentiation	nucleus	DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity				0	all_neural(89;0.0646)|Medulloblastoma(90;0.163)					GTAGACGCTTGGCCTCGTCGATGAACGGCCGCTTC	0.614													---	---	---							
TOX4	9878	broad.mit.edu	37	14	21963465	21963466	+	Frame_Shift_Ins	INS	-	A	A			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr14:21963465_21963466insA	uc001waz.2	+	8	1822_1823	c.1719_1720insA	c.(1717-1722)GTGAGGfs	p.V573fs	TOX4_uc001way.2_Frame_Shift_Ins_p.V443fs|TOX4_uc001wba.2_RNA|TOX4_uc010tlu.1_Frame_Shift_Ins_p.V550fs|TOX4_uc010tlv.1_Frame_Shift_Ins_p.V443fs	NM_014828	NP_055643	O94842	TOX4_HUMAN	epidermal Langerhans cell protein LCP1	573_574						chromatin|nucleus|PTW/PP1 phosphatase complex	DNA binding|protein binding			ovary(1)	1	all_cancers(95;0.000465)		Epithelial(56;6.61e-06)|all cancers(55;5.15e-05)	GBM - Glioblastoma multiforme(265;0.0149)		CTCGATGTGTGAGGTCTGGTTG	0.505													---	---	---							
Unknown	0	broad.mit.edu	37	14	51590417	51590418	+	IGR	INS	-	GT	GT	rs139362655	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr14:51590417_51590418insGT								TRIM9 (27995 upstream) : TMX1 (116468 downstream)																							ccttcaagccagtgtgtgtgtg	0.000													---	---	---							
Unknown	0	broad.mit.edu	37	15	44497236	44497237	+	IGR	INS	-	GGAA	GGAA	rs67250570		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr15:44497236_44497237insGGAA								FRMD5 (9807 upstream) : CASC4 (83692 downstream)																							aagggagggagggaaggaagga	0.000													---	---	---							
TP53	7157	broad.mit.edu	37	17	7579514	7579514	+	Frame_Shift_Del	DEL	G	-	-	rs144386518		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:7579514delG	uc002gim.2	-	4	367	c.173delC	c.(172-174)CCAfs	p.P58fs	TP53_uc002gig.1_Frame_Shift_Del_p.P58fs|TP53_uc002gih.2_Frame_Shift_Del_p.P58fs|TP53_uc010cne.1_5'Flank|TP53_uc010cnf.1_5'Flank|TP53_uc010cng.1_5'Flank|TP53_uc002gii.1_5'Flank|TP53_uc010cnh.1_Frame_Shift_Del_p.P58fs|TP53_uc010cni.1_Frame_Shift_Del_p.P58fs|TP53_uc002gij.2_Frame_Shift_Del_p.P58fs|TP53_uc010cnj.1_5'Flank|TP53_uc002gin.2_Intron|TP53_uc002gio.2_Intron|TP53_uc010vug.1_Frame_Shift_Del_p.P19fs|TP53_uc010cnk.1_Frame_Shift_Del_p.P73fs	NM_001126112	NP_001119584	P04637	P53_HUMAN	tumor protein p53 isoform a	58	Interaction with HRMT1L2.		P -> T (in a sporadic cancer; somatic mutation).|P -> Q (in a sporadic cancer; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.0?(7)|p.P58L(1)|p.P58fs*65(1)|p.E51fs*59(1)|p.D48fs*55(1)|p.P13fs*18(1)|p.S33fs*23(1)|p.D57_A76del20(1)|p.D57fs*86(1)|p.P58Q(1)		large_intestine(4656)|breast(2429)|upper_aerodigestive_tract(2212)|lung(2028)|ovary(1592)|oesophagus(1462)|haematopoietic_and_lymphoid_tissue(1228)|stomach(1136)|urinary_tract(1114)|central_nervous_system(1085)|liver(805)|skin(694)|pancreas(375)|biliary_tract(247)|soft_tissue(209)|prostate(194)|endometrium(150)|bone(102)|vulva(79)|kidney(79)|cervix(68)|thyroid(54)|salivary_gland(43)|adrenal_gland(37)|peritoneum(33)|eye(24)|thymus(21)|genital_tract(16)|autonomic_ganglia(16)|small_intestine(14)|testis(11)|penis(10)|vagina(6)|meninges(5)|pituitary(4)|pleura(3)|gastrointestinal_tract_(site_indeterminate)(1)|NS(1)|Fallopian tube(1)|placenta(1)	22245		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		ATCTGGACCTGGGTCTTCAGT	0.602		111	Mis|N|F		breast|colorectal|lung|sarcoma|adrenocortical|glioma|multiple other tumour types	breast|sarcoma|adrenocortical carcinoma|glioma|multiple other tumour types		Other_conserved_DNA_damage_response_genes	Hereditary_Adrenocortical_Cancer|Endometrial_Cancer_Familial_Clustering_of|Hereditary_Breast-Ovarian_Cancer_non-BRCA1/2|Li-Fraumeni_syndrome|Osteosarcoma_Familial_Clustering_of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			---	---	---							
Unknown	0	broad.mit.edu	37	17	21518737	21518737	+	IGR	DEL	A	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:21518737delA								C17orf51 (41006 upstream) : FAM27L (306633 downstream)																							TATTGGTAGCAAAACAGCCAT	0.259													---	---	---							
CYB561	1534	broad.mit.edu	37	17	61511870	61511870	+	Frame_Shift_Del	DEL	A	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr17:61511870delA	uc002jap.2	-	5	1051	c.649delT	c.(649-651)TACfs	p.Y217fs	CYB561_uc002jaq.2_Frame_Shift_Del_p.Y263fs|CYB561_uc002jar.2_Frame_Shift_Del_p.Y217fs|CYB561_uc002jas.2_Frame_Shift_Del_p.Y217fs|CYB561_uc010ddt.2_3'UTR|CYB561_uc002jat.2_Frame_Shift_Del_p.Y217fs|CYB561_uc010wpf.1_3'UTR|CYB561_uc010wpg.1_Frame_Shift_Del_p.Y188fs	NM_001915	NP_001906	P49447	CY561_HUMAN	cytochrome b-561	217	Cytochrome b561.|Helical; (Potential).				electron transport chain|transport	integral to plasma membrane	cytochrome-b5 reductase activity|ferric-chelate reductase activity|metal ion binding			ovary(1)	1				READ - Rectum adenocarcinoma(1115;0.0689)		GTCAAGATGTAGAGCACCGCC	0.657													---	---	---							
Unknown	0	broad.mit.edu	37	18	23569461	23569462	+	IGR	INS	-	AAGG	AAGG	rs72480940		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr18:23569461_23569462insAAGG								ZNF521 (637247 upstream) : SS18 (26757 downstream)																							GTGAGACTCgaaaggaaggaag	0.129													---	---	---							
PPP2R1A	5518	broad.mit.edu	37	19	52724304	52724305	+	Frame_Shift_Ins	INS	-	T	T	rs141690261		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr19:52724304_52724305insT	uc002pyp.2	+	12	1595_1596	c.1436_1437insT	c.(1435-1437)CATfs	p.H479fs	PPP2R1A_uc010ydk.1_Frame_Shift_Ins_p.H424fs|PPP2R1A_uc002pyq.2_Frame_Shift_Ins_p.H300fs	NM_014225	NP_055040	P30153	2AAA_HUMAN	alpha isoform of regulatory subunit A, protein	479	PP2A subunit C binding.|HEAT 13.				ceramide metabolic process|chromosome segregation|G2/M transition of mitotic cell cycle|inactivation of MAPK activity|induction of apoptosis|negative regulation of cell growth|negative regulation of tyrosine phosphorylation of Stat3 protein|protein complex assembly|protein dephosphorylation|regulation of cell adhesion|regulation of cell differentiation|regulation of DNA replication|regulation of transcription, DNA-dependent|regulation of Wnt receptor signaling pathway|response to organic substance|RNA splicing|second-messenger-mediated signaling	chromosome, centromeric region|cytosol|membrane|microtubule cytoskeleton|mitochondrion|nucleus|protein phosphatase type 2A complex|soluble fraction	antigen binding|protein heterodimerization activity|protein phosphatase type 2A regulator activity			endometrium(31)|ovary(28)|lung(2)|breast(2)|skin(1)|kidney(1)|pancreas(1)	66				GBM - Glioblastoma multiforme(134;0.00456)|OV - Ovarian serous cystadenocarcinoma(262;0.015)		GAGTGGGCCCATGCCACAATCA	0.559			Mis		clear cell ovarian carcinoma								---	---	---							
Unknown	0	broad.mit.edu	37	2	162135412	162135413	+	IGR	INS	-	GTCT	GTCT	rs59606723	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr2:162135412_162135413insGTCT								TANK (42730 upstream) : PSMD14 (29373 downstream)																							tccttccttccttccttccttc	0.238													---	---	---							
Unknown	0	broad.mit.edu	37	20	4591050	4591051	+	IGR	INS	-	AAGG	AAGG	rs142350237	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:4591050_4591051insAAGG								ADRA1D (361391 upstream) : PRNP (75746 downstream)																							agaaagaaagaaaggaaggaag	0.000													---	---	---							
Unknown	0	broad.mit.edu	37	20	49061025	49061026	+	IGR	DEL	GT	-	-	rs11467769		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:49061025_49061026delGT								CEBPB (251813 upstream) : PTPN1 (65865 downstream)																							gtgcacgtgcgtgtgtgtgtgt	0.124													---	---	---							
TFAP2C	7022	broad.mit.edu	37	20	55208539	55208540	+	Frame_Shift_Ins	INS	-	T	T			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr20:55208539_55208540insT	uc002xya.2	+	4	960_961	c.717_718insT	c.(715-720)AAATACfs	p.K239fs	TFAP2C_uc010zzi.1_Frame_Shift_Ins_p.K70fs	NM_003222	NP_003213	Q92754	AP2C_HUMAN	transcription factor AP-2 gamma	239_240					cell-cell signaling|male gonad development|regulation of transcription from RNA polymerase II promoter	nucleus	DNA binding|protein dimerization activity|sequence-specific DNA binding transcription factor activity			central_nervous_system(1)	1			Colorectal(105;0.229)			CTACGTCTAAATACAAAGTGAC	0.535													---	---	---							
Unknown	0	broad.mit.edu	37	21	44756729	44756730	+	IGR	INS	-	CAT	CAT			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr21:44756729_44756730insCAT								CRYAA (163816 upstream) : SIK1 (77668 downstream)																							accaccatcaccaccaccacca	0.000													---	---	---							
Unknown	0	broad.mit.edu	37	3	194711806	194711807	+	IGR	INS	-	TTG	TTG	rs113163891		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr3:194711806_194711807insTTG								FAM43A (302042 upstream) : C3orf21 (77208 downstream)																							cttcctcctcctcctcttcctc	0.054													---	---	---							
Unknown	0	broad.mit.edu	37	5	180722144	180722144	+	IGR	DEL	T	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr5:180722144delT								TRIM52 (34025 upstream) : None (None downstream)																							CCCAAAGGAAttttttttttt	0.219													---	---	---							
Unknown	0	broad.mit.edu	37	6	108418444	108418444	+	IGR	DEL	A	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr6:108418444delA								OSTM1 (22503 upstream) : NR2E1 (68771 downstream)																							gaccctatctaaaaaaaaaaa	0.000													---	---	---							
STAG3L2	442582	broad.mit.edu	37	7	74300557	74300564	+	Frame_Shift_Del	DEL	AGAGCTCC	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:74300557_74300564delAGAGCTCC	uc003ubj.3	-	5	625_632	c.243_250delGGAGCTCT	c.(241-252)CTGGAGCTCTTCfs	p.L81fs	STAG3L2_uc011kfj.1_RNA	NM_001025202	NP_001020373	P0CL84	ST3L2_HUMAN	STAG3-like	81_84	SCD.					nucleus	binding				0						CGGCCAGTGAAGAGCTCCAGGCGTGCGG	0.572													---	---	---							
Unknown	0	broad.mit.edu	37	7	77612634	77612635	+	IGR	INS	-	TTCC	TTCC	rs13240757	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:77612634_77612635insTTCC								PHTF2 (25816 upstream) : MAGI2 (33740 downstream)																							tctttctttctttccttccttc	0.079													---	---	---							
Unknown	0	broad.mit.edu	37	7	152144400	152144400	+	IGR	DEL	T	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:152144400delT								FABP5L3 (4302 upstream) : LOC100128822 (16809 downstream)																							AGTTCTCGAAttttttttttt	0.149													---	---	---							
Unknown	0	broad.mit.edu	37	7	155739522	155739525	+	IGR	DEL	TTCC	-	-	rs5888641		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr7:155739522_155739525delTTCC								SHH (134555 upstream) : C7orf4 (593660 downstream)																							ccttccttctttccttccttcctt	0.000													---	---	---							
Unknown	0	broad.mit.edu	37	8	41041781	41041781	+	IGR	DEL	A	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:41041781delA								ZMAT4 (286438 upstream) : SFRP1 (77698 downstream)																							actctgtctcaaaaaaaaaaa	0.000													---	---	---							
Unknown	0	broad.mit.edu	37	8	65452812	65452819	+	IGR	DEL	GAAGTAAG	-	-	rs111520606	by1000genomes	TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:65452812_65452819delGAAGTAAG								MIR124-2 (160998 upstream) : LOC401463 (34049 downstream)																							gagagagagagaagtaaggaaggaagga	0.010													---	---	---							
Unknown	0	broad.mit.edu	37	8	86975391	86975392	+	IGR	INS	-	TG	TG	rs56919238		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr8:86975391_86975392insTG								REXO1L1 (400123 upstream) : PSKH2 (85301 downstream)																							gtgtgtgtgtgtACACTGGGGC	0.218													---	---	---							
FLJ43950	347127	broad.mit.edu	37	9	84528568	84528568	+	Frame_Shift_Del	DEL	A	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr9:84528568delA	uc011lst.1	+	1	217	c.116delA	c.(115-117)CAAfs	p.Q39fs		NR_026851				SubName: Full=cDNA FLJ43950 fis, clone TESTI4015293, moderately similar to FAM75-like protein;												0						AATGATATCCAAAAGGTAAGG	0.398													---	---	---							
Unknown	0	broad.mit.edu	37	9	133834072	133834074	+	IGR	DEL	TGT	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chr9:133834072_133834074delTGT								FIBCD1 (19617 upstream) : LAMC3 (50430 downstream)																							tcaccaccactgtcatcaccatc	0.000													---	---	---							
Unknown	0	broad.mit.edu	37	X	2042213	2042214	+	IGR	DEL	CA	-	-			TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chrX:2042213_2042214delCA								ASMT (280240 upstream) : DHRSX (95343 downstream)																							GTGCACCACCCACACACACACA	0.109													---	---	---							
Unknown	0	broad.mit.edu	37	X	150192021	150192022	+	IGR	INS	-	T	T	rs34005723		TCGA-CN-4728-01A-01D-1434-08	TCGA-CN-4728-10A-01D-1434-08									Somatic	Phase_I	Capture				Illumina GAIIx	e450fec8-66dd-4798-8197-4206b8ba7c4d	4b1d7980-d6aa-4c96-b019-228d9243d7be	g.chrX:150192021_150192022insT								HMGB3 (32775 upstream) : GPR50 (153037 downstream)																							ACTGTCAATTCTTTTTTTTTTT	0.223													---	---	---							
