Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
WT1	7490	broad.mit.edu	37	11	32414222	32414222	+	Missense_Mutation	SNP	C	A	A			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr11:32414222C>A	uc001mtn.1	-	8	1525	c.1329G>T	c.(1327-1329)AGG>AGT	p.R443S	WT1_uc001mtl.1_Missense_Mutation_p.R231S|WT1_uc001mtm.1_Missense_Mutation_p.R214S|WT1_uc001mto.1_Missense_Mutation_p.R443S|WT1_uc001mtp.1_Missense_Mutation_p.R426S|WT1_uc001mtq.1_Missense_Mutation_p.R426S|WT1_uc009yjs.1_RNA	NM_024426	NP_077744	P19544	WT1_HUMAN	Wilms tumor 1 isoform D	375	C2H2-type 2.|Important for interaction with target DNA.				adrenal cortex formation|branching involved in ureteric bud morphogenesis|camera-type eye development|cardiac muscle cell fate commitment|cellular response to cAMP|cellular response to gonadotropin stimulus|germ cell development|glomerular basement membrane development|glomerular visceral epithelial cell differentiation|induction of apoptosis|male genitalia development|male gonad development|mesenchymal to epithelial transition|metanephric epithelium development|metanephric S-shaped body morphogenesis|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of female gonad development|negative regulation of metanephric glomerular mesangial cell proliferation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-dependent|negative regulation of translation|positive regulation of male gonad development|positive regulation of transcription, DNA-dependent|posterior mesonephric tubule development|regulation of organ formation|RNA splicing|sex determination|vasculogenesis|visceral serous pericardium development	cytoplasm|nuclear speck|nucleoplasm	C2H2 zinc finger domain binding|RNA binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|zinc ion binding		EWSR1/WT1(231)	haematopoietic_and_lymphoid_tissue(318)|soft_tissue(231)|kidney(132)|pleura(2)|lung(2)|upper_aerodigestive_tract(1)|peritoneum(1)	687	Breast(20;0.247)		OV - Ovarian serous cystadenocarcinoma(30;0.128)			CTGTATGTCTCCTTTGGTGTC	0.438000			D|Mis|N|F|S	EWSR1	Wilms|desmoplastic small round cell tumor	Wilms			Denys-Drash_syndrome|Frasier_syndrome|Familial_Wilms_tumor|Wilms_tumor-Aniridia-ambiguous_Genitals-mental_Retardation				4	32	---	---	---	---	0.00024832	0.00029488	0.009096	1	0
KRT79	338785	broad.mit.edu	37	12	53225273	53225273	+	Silent	SNP	C	T	T			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr12:53225273C>T	uc001sbb.2	-	2	648	c.615G>A	c.(613-615)ACG>ACA	p.T205T	KRT79_uc001sba.2_5'Flank	NM_175834	NP_787028	Q5XKE5	K2C79_HUMAN	keratin 6L	205	Rod.|Coil 1B.					keratin filament	structural molecule activity			ovary(2)|skin(2)	4						GTCTGTCCAGCGTGCTCCGCA	0.607000													22	83	---	---	---	---	0	0	0.076483	0	0
ZNF319	57567	broad.mit.edu	37	16	58031260	58031260	+	Nonsense_Mutation	SNP	G	A	A			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr16:58031260G>A	uc002emx.1	-	2	1533	c.910C>T	c.(910-912)CAG>TAG	p.Q304*		NM_020807	NP_065858	Q9P2F9	ZN319_HUMAN	zinc finger protein 319	304	C2H2-type 7; degenerate.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0						CACGGGTGCTGCAGCAGCTCC	0.662000													3	29	---	---	---	---	0	0	0.009096	0	0
Unknown	0	broad.mit.edu	37	16	90161578	90161578	+	Silent	SNP	G	A	A	rs13337896	by1000genomes	TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr16:90161578G>A	uc002fqp.2	+	3	931	c.453G>A	c.(451-453)ACG>ACA	p.T151T	uc002fqq.2_Silent_p.T168T					Homo sapiens, Similar to tubulin, beta, 2, clone IMAGE:4873024, mRNA.																		GCCAAGGGACGCTACACCGAA	0.587000													3	30	---	---	---	---	0	0	0.004672	0	0
NRP2	8828	broad.mit.edu	37	2	206630290	206630290	+	Silent	SNP	C	T	T			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr2:206630290C>T	uc002vaw.2	+	14	3191	c.2400C>T	c.(2398-2400)TGC>TGT	p.C800C	NRP2_uc002vau.2_Silent_p.C800C|NRP2_uc002vav.2_Silent_p.C800C|NRP2_uc002vax.2_Silent_p.C800C|NRP2_uc002vay.2_Silent_p.C800C	NM_201266	NP_957718	O60462	NRP2_HUMAN	neuropilin 2 isoform 1 precursor	800	Extracellular (Potential).|MAM.				angiogenesis|axon guidance|cell adhesion	integral to membrane|membrane fraction|plasma membrane	heparin binding|metal ion binding|semaphorin receptor activity|vascular endothelial growth factor receptor activity			skin(2)|ovary(1)|central_nervous_system(1)	4						TGGAGAACTGCATGGGTATGT	0.478000													4	96	---	---	---	---	0	0	0.009096	0	0
PTPRT	11122	broad.mit.edu	37	20	41306647	41306647	+	Missense_Mutation	SNP	G	A	A			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr20:41306647G>A	uc002xkg.2	-	7	1196	c.1012C>T	c.(1012-1014)CAC>TAC	p.H338Y	PTPRT_uc010ggj.2_Missense_Mutation_p.H338Y	NM_007050	NP_008981	O14522	PTPRT_HUMAN	protein tyrosine phosphatase, receptor type, T	338	Extracellular (Potential).|Fibronectin type-III 1.				homophilic cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway	cell surface|integral to membrane|plasma membrane	alpha-catenin binding|beta-catenin binding|cadherin binding|delta-catenin binding|gamma-catenin binding|protein tyrosine phosphatase activity|receptor activity			skin(8)|ovary(7)|lung(5)	20		Myeloproliferative disorder(115;0.00452)|Lung NSC(126;0.0573)|all_lung(126;0.0783)				TCGACTATGTGGGTCTCTGCC	0.567000													14	115	---	---	---	---	0	0	0.020292	0	0
ZFP42	132625	broad.mit.edu	37	4	188924090	188924090	+	Silent	SNP	C	T	T			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr4:188924090C>T	uc003izg.1	+	3	374	c.129C>T	c.(127-129)GTC>GTT	p.V43V	ZFP42_uc003izh.1_Silent_p.V43V|ZFP42_uc003izi.1_Silent_p.V43V	NM_174900	NP_777560	Q96MM3	ZFP42_HUMAN	zinc finger protein 42	43					female gonad development|male gonad development|meiosis	cytoplasm|nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(1)|skin(1)	2		all_cancers(14;6.2e-52)|all_epithelial(14;7.36e-37)|all_lung(41;2.29e-15)|Lung NSC(41;6.7e-15)|Breast(6;1.53e-05)|Melanoma(20;3.01e-05)|Hepatocellular(41;0.00335)|all_hematologic(60;0.014)|Renal(120;0.0183)|Prostate(90;0.0421)|Colorectal(36;0.227)		OV - Ovarian serous cystadenocarcinoma(60;1.54e-11)|BRCA - Breast invasive adenocarcinoma(30;4.21e-06)|GBM - Glioblastoma multiforme(59;8.93e-05)|STAD - Stomach adenocarcinoma(60;0.000279)|LUSC - Lung squamous cell carcinoma(40;0.00902)|READ - Rectum adenocarcinoma(43;0.157)		TAGAACCTGTCAGCGCGGTGT	0.562000													25	40	---	---	---	---	0	0	0.099896	0	0
SKAP2	8935	broad.mit.edu	37	7	26766512	26766512	+	Missense_Mutation	SNP	G	A	A			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr7:26766512G>A	uc003syc.2	-	7	876	c.583C>T	c.(583-585)CGT>TGT	p.R195C	SKAP2_uc011jzi.1_Missense_Mutation_p.R23C|SKAP2_uc011jzj.1_Missense_Mutation_p.R180C	NM_003930	NP_003921	O75563	SKAP2_HUMAN	src kinase associated phosphoprotein 2	195	PH.				B cell activation|cell junction assembly|protein complex assembly|signal transduction	cytosol|plasma membrane	SH3/SH2 adaptor activity			pancreas(1)	1						TGATATATACGTTTATCAGGA	0.303000													15	34	---	---	---	---	0	0	0.033300	0	0
ASMT	438	broad.mit.edu	37	X	1743168	1743168	+	Missense_Mutation	SNP	A	G	G			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chrX:1743168A>G	uc004cqd.2	+	4	396	c.251A>G	c.(250-252)TAT>TGT	p.Y84C	ASMT_uc010ncy.2_Missense_Mutation_p.Y84C|ASMT_uc004cqe.2_Missense_Mutation_p.Y84C	NM_004043	NP_004034	P46597	HIOM_HUMAN	acetylserotonin O-methyltransferase	84					melatonin biosynthetic process|translation	cytosol	acetylserotonin O-methyltransferase activity|S-methyltransferase activity			skin(1)	1		all_cancers(21;4.28e-07)|all_epithelial(21;2.07e-08)|all_lung(23;2.81e-05)|Lung NSC(23;0.000693)|Lung SC(21;0.122)				TCAGCTTTCTATCGAAACACA	0.537000													35	96	---	---	---	---	0	0	0.069456	0	0
Unknown	0	broad.mit.edu	37	11	9628181	9628182	+	IGR	INS	-	AT	AT	rs140957951	by1000genomes	TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr11:9628181_9628182insAT								WEE1 (16870 upstream) : SWAP70 (57446 downstream)																							CCTAATTCTAAATATACATATA	0.228													5	7	---	---	---	---					
Unknown	0	broad.mit.edu	37	11	23542751	23542751	+	IGR	DEL	T	-	-			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr11:23542751delT								SVIP (691369 upstream) : LUZP2 (975805 downstream)																							CAACATAGGATTTTTTTACAA	0.284													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	17	25289230	25289233	+	IGR	DEL	TCTA	-	-	rs138697975		TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr17:25289230_25289233delTCTA								None (None upstream) : WSB1 (331873 downstream)																							GTTTGTTACCTCTATCTATTGACT	0.343													3	3	---	---	---	---					
Unknown	0	broad.mit.edu	37	19	53703995	53703995	+	IGR	DEL	T	-	-	rs113703393		TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr19:53703995delT								ZNF665 (7376 upstream) : ZNF677 (34643 downstream)																							TGTTTCCCCCttttttttttt	0.229													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	2	92068309	92068310	+	IGR	INS	-	A	A			TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr2:92068309_92068310insA								GGT8P (98156 upstream) : FKSG73 (60849 downstream)																							AAATACTATGGAAAAAATTTGT	0.292													5	6	---	---	---	---					
Unknown	0	broad.mit.edu	37	2	133020743	133020744	+	IGR	INS	-	T	T	rs137914230		TCGA-EM-A1YD-01A-11D-A14W-08	TCGA-EM-A1YD-11A-11D-A14W-08									Somatic	Phase_I	Capture				Illumina GAIIx	aafa9d53-6742-48e3-ac67-7be5f7f48aa6	357a4434-cd9f-4fc5-bab7-5ef3a14fc76e	g.chr2:133020743_133020744insT								NCRNA00164 (5201 upstream) : GPR39 (153403 downstream)																							TTAGATAGCTCTTTATTGTCAT	0.327													4	3	---	---	---	---					
