Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FAM40A	85369	broad.mit.edu	37	1	110584240	110584240	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr1:110584240C>T	uc001dza.1	+	7	752	c.733C>T	c.(733-735)CGG>TGG	p.R245W	FAM40A_uc001dyz.1_Missense_Mutation_p.R150W|FAM40A_uc009wfp.1_Missense_Mutation_p.R69W	NM_033088	NP_149079	Q5VSL9	FA40A_HUMAN	hypothetical protein LOC85369	245						nucleus	protein binding			ovary(3)|large_intestine(1)	4		all_cancers(81;8.51e-05)|all_epithelial(167;3.58e-05)|all_lung(203;0.000116)|Lung NSC(277;0.000233)		Lung(183;0.0154)|all cancers(265;0.0732)|Epithelial(280;0.0781)|Colorectal(144;0.115)|LUSC - Lung squamous cell carcinoma(189;0.137)		GAGGACCATGCGGCAGACCTT	0.592000													3	31					0	0	0.115264	0	0
NBPF10	100132406	broad.mit.edu	37	1	145327544	145327544	+	Silent	SNP	A	C	C			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr1:145327544A>C	uc001end.3	+	34	4361	c.4326A>C	c.(4324-4326)TCA>TCC	p.S1442S	NBPF10_uc009wir.2_Intron|NBPF9_uc010oye.1_Intron|NBPF10_uc001emp.3_Intron|NBPF10_uc010oyi.1_Intron|NBPF10_uc010oyk.1_Intron|NBPF10_uc010oyl.1_Intron|NBPF10_uc001enc.2_Intron|NBPF10_uc010oym.1_Intron|NBPF10_uc010oyn.1_Intron|NBPF10_uc010oyo.1_Intron|NBPF10_uc010oyp.1_Intron	NM_001039703	NP_001034792	A6NDV3	A6NDV3_HUMAN	hypothetical protein LOC100132406	1367											0	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		TGCAGGACTCACTGAATAGAT	0.473000													2	4					0	0	0.115264	0	0
KPRP	448834	broad.mit.edu	37	1	152733157	152733157	+	Missense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr1:152733157G>A	uc001fal.1	+	2	1151	c.1093G>A	c.(1093-1095)GCC>ACC	p.A365T		NM_001025231	NP_001020402	Q5T749	KPRP_HUMAN	keratinocyte proline-rich protein	365	Pro-rich.					cytoplasm				ovary(4)|pancreas(1)	5	Hepatocellular(266;0.0877)|all_hematologic(923;0.127)|Melanoma(130;0.242)		LUSC - Lung squamous cell carcinoma(543;0.206)			CTCCTGGGGCGCCTCCTGCCC	0.662000													13	75					0	0	0.435327	0	0
BAT2L2	23215	broad.mit.edu	37	1	171511013	171511013	+	Missense_Mutation	SNP	C	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr1:171511013C>G	uc010pmg.1	+	16	4668	c.4402C>G	c.(4402-4404)CCA>GCA	p.P1468A	BAT2L2_uc010pmh.1_Missense_Mutation_p.P445A	NM_015172	NP_055987	Q9Y520	PRC2C_HUMAN	HBxAg transactivated protein 2	1468							protein C-terminus binding				0						GGCTCAAGAACCAGTTAATAC	0.428000													4	55					0	0	0.217242	0	0
CHRM3	1131	broad.mit.edu	37	1	240070879	240070879	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr1:240070879C>T	uc001hyp.2	+	5	907	c.128C>T	c.(127-129)TCT>TTT	p.S43F		NM_000740	NP_000731	P20309	ACM3_HUMAN	cholinergic receptor, muscarinic 3	43	Extracellular (By similarity).				cell proliferation|energy reserve metabolic process|nervous system development|protein modification process|regulation of insulin secretion	basolateral plasma membrane|cell junction|integral to plasma membrane|postsynaptic membrane	muscarinic acetylcholine receptor activity|phosphatidylinositol phospholipase C activity			ovary(4)|skin(1)	5	Ovarian(103;0.127)	all_cancers(173;0.00567)|all_neural(198;0.203)	OV - Ovarian serous cystadenocarcinoma(106;0.00989)		Anisotropine Methylbromide(DB00517)|Atropine(DB00572)|Benzquinamide(DB00767)|Cevimeline(DB00185)|Cryptenamine(DB00785)|Cyclizine(DB01176)|Darifenacin(DB00496)|Diphemanil Methylsulfate(DB00729)|Diphenidol(DB01231)|Homatropine Methylbromide(DB00725)|Methotrimeprazine(DB01403)|Metixene(DB00340)|Olanzapine(DB00334)|Oxybutynin(DB01062)|Oxyphencyclimine(DB00383)|Promazine(DB00420)|Promethazine(DB01069)|Propiomazine(DB00777)|Solifenacin(DB01591)|Thiethylperazine(DB00372)|Tiotropium(DB01409)|Tolterodine(DB01036)|Tridihexethyl(DB00505)	TACAATGTTTCTCGAGCAGCT	0.562000													6	108					0	0	0.248553	0	0
KIAA1217	56243	broad.mit.edu	37	10	24832988	24832988	+	Nonsense_Mutation	SNP	A	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr10:24832988A>T	uc001iru.3	+	19	5192	c.4789A>T	c.(4789-4791)AAG>TAG	p.K1597*	KIAA1217_uc001irs.2_Intron|KIAA1217_uc001irt.3_Intron|KIAA1217_uc010qcy.1_Intron|KIAA1217_uc010qcz.1_Intron|KIAA1217_uc001irw.2_Intron|KIAA1217_uc001irz.2_Intron|KIAA1217_uc001irx.2_Nonsense_Mutation_p.K1280*|KIAA1217_uc001iry.2_Intron|KIAA1217_uc001isa.1_Nonsense_Mutation_p.K433*	NM_019590	NP_062536	Q5T5P2	SKT_HUMAN	sickle tail isoform 1	1597					embryonic skeletal system development	cytoplasm				ovary(5)|skin(2)	7						TAAAACAGGGAAGAAGACTTT	0.463000													11	91					0	0	0.411799	0	0
AGAP5	729092	broad.mit.edu	37	10	75457306	75457306	+	Nonsense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr10:75457306G>A	uc009xri.2	-	1	249	c.208C>T	c.(208-210)CAG>TAG	p.Q70*	AGAP5_uc001juu.3_Nonsense_Mutation_p.Q31*	NM_001144000	NP_001137472	A6NIR3	AGAP5_HUMAN	ArfGAP with GTPase domain, ankyrin repeat and PH	70					regulation of ARF GTPase activity		ARF GTPase activator activity|zinc ion binding				0						GGCATCTCCTGGTCACGAATG	0.592000													13	172					0	0	0.479597	0	0
HELLS	3070	broad.mit.edu	37	10	96352241	96352241	+	Silent	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr10:96352241G>A	uc001kjt.2	+	17	2046	c.1941G>A	c.(1939-1941)GGG>GGA	p.G647G	HELLS_uc001kjs.2_Silent_p.G631G|HELLS_uc009xul.2_Silent_p.G549G|HELLS_uc009xum.2_Silent_p.G517G|HELLS_uc009xun.2_Silent_p.G523G|HELLS_uc009xuo.2_Silent_p.G693G|HELLS_uc001kju.2_Silent_p.G286G|HELLS_uc009xup.2_RNA|HELLS_uc009xuq.2_Silent_p.G509G|HELLS_uc009xur.2_RNA	NM_018063	NP_060533	Q9NRZ9	HELLS_HUMAN	helicase, lymphoid-specific	647	Helicase C-terminal.				cell division|centromeric heterochromatin formation|lymphocyte proliferation|maintenance of DNA methylation|methylation-dependent chromatin silencing|mitosis|transcription, DNA-dependent	centromeric heterochromatin|nucleus	ATP binding|DNA binding|helicase activity			ovary(1)|kidney(1)	2		Colorectal(252;0.0429)		all cancers(201;2.13e-05)		GGCTTGATGGGTCCATGTCTT	0.343000													8	31					0	0	0.387290	0	0
SLIT1	6585	broad.mit.edu	37	10	98764460	98764460	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr10:98764460C>T	uc001kmw.2	-	33	3952	c.3700G>A	c.(3700-3702)GCC>ACC	p.A1234T		NM_003061	NP_003052	O75093	SLIT1_HUMAN	slit homolog 1 precursor	1234	Laminin G-like.				axon extension involved in axon guidance|forebrain morphogenesis|motor axon guidance|negative chemotaxis|negative regulation of synaptogenesis	cytoplasm|extracellular space	calcium ion binding|Roundabout binding			ovary(4)	4		Colorectal(252;0.162)		Epithelial(162;2.02e-08)|all cancers(201;1.5e-06)		CTGTAGATGGCAGAGCTGGGG	0.602000													14	49					0	0	0.457914	0	0
DIXDC1	85458	broad.mit.edu	37	11	111835363	111835363	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr11:111835363C>T	uc001pml.2	+	2	448	c.151C>T	c.(151-153)CGG>TGG	p.R51W	DIXDC1_uc001pmj.2_Missense_Mutation_p.R44W|DIXDC1_uc001pmk.2_Missense_Mutation_p.R51W	NM_001037954	NP_001033043	Q155Q3	DIXC1_HUMAN	DIX domain containing 1 isoform a	51	CH.				multicellular organismal development|positive regulation of canonical Wnt receptor signaling pathway|Wnt receptor signaling pathway	cytosol|focal adhesion	actin binding|gamma-tubulin binding|signal transducer activity			ovary(1)	1		all_cancers(61;7.58e-15)|all_epithelial(67;5.42e-09)|Melanoma(852;1.91e-06)|all_hematologic(158;0.000405)|Acute lymphoblastic leukemia(157;0.000967)|Breast(348;0.0112)|all_neural(223;0.0281)|Medulloblastoma(222;0.0425)		Epithelial(105;2.99e-07)|BRCA - Breast invasive adenocarcinoma(274;6.72e-07)|all cancers(92;6.25e-06)|OV - Ovarian serous cystadenocarcinoma(223;0.0548)		ACAAGATCTCCGGGATGGGGT	0.517000													7	9					0	0	0.335167	0	0
TTC12	54970	broad.mit.edu	37	11	113215006	113215006	+	Missense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr11:113215006G>A	uc001pnu.2	+	13	1103	c.998G>A	c.(997-999)CGT>CAT	p.R333H	TTC12_uc001pnv.2_Missense_Mutation_p.R339H|TTC12_uc001pnw.2_RNA|TTC12_uc001pnx.2_Missense_Mutation_p.R183H	NM_017868	NP_060338	Q9H892	TTC12_HUMAN	tetratricopeptide repeat domain 12	333							binding			pancreas(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)	4		all_cancers(61;2.73e-16)|all_epithelial(67;8.64e-10)|Melanoma(852;1.46e-05)|all_hematologic(158;0.00014)|Acute lymphoblastic leukemia(157;0.000967)|Breast(348;0.0101)|all_neural(223;0.0281)|Medulloblastoma(222;0.0425)|Prostate(24;0.183)|Renal(330;0.187)		BRCA - Breast invasive adenocarcinoma(274;5.3e-06)|Epithelial(105;8.37e-05)|all cancers(92;0.000694)		GAAAACCAGCGTGTGCTAGTG	0.532000													69	113					0	0	0.870114	0	0
MAP3K12	7786	broad.mit.edu	37	12	53877509	53877509	+	Splice_Site	SNP	T	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr12:53877509T>A	uc001sdm.1	-	10	1358	c.1260_splice	c.e10-1	p.R420_splice	MAP3K12_uc001sdn.1_Splice_Site_p.R453_splice	NM_006301	NP_006292	Q12852	M3K12_HUMAN	mitogen-activated protein kinase kinase kinase						histone phosphorylation|JNK cascade|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|protein autophosphorylation	cytosol|membrane fraction|plasma membrane	ATP binding|magnesium ion binding|MAP kinase kinase kinase activity|protein homodimerization activity|protein kinase binding			lung(2)|ovary(1)|breast(1)|skin(1)	5						AGGGCGTGTCTGCAACGGGCA	0.507000													8	50					0	0	0.278610	0	0
SMUG1	23583	broad.mit.edu	37	12	54577582	54577582	+	Missense_Mutation	SNP	G	A	A	rs149806805	byFrequency	TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr12:54577582G>A	uc001sff.1	-	3	272	c.143C>T	c.(142-144)TCG>TTG	p.S48L	SMUG1_uc001sfa.1_5'Flank|SMUG1_uc001sfe.1_Missense_Mutation_p.S48L|SMUG1_uc001sfg.1_Missense_Mutation_p.S48L|SMUG1_uc009znf.1_Missense_Mutation_p.S48L|SMUG1_uc001sfb.3_Missense_Mutation_p.S48L|SMUG1_uc001sfc.3_Missense_Mutation_p.S48L|SMUG1_uc001sfd.3_Missense_Mutation_p.S48L	NM_014311	NP_055126	Q53HV7	SMUG1_HUMAN	single-strand-selective monofunctional	48				S -> L (in Ref. 3; BAC03670).	depyrimidination	nucleolus|nucleoplasm	DNA binding|protein binding|single-strand selective uracil DNA N-glycosylase activity				0						CACAGGCTCCGAAAACTGCAG	0.597000								BER_DNA_glycosylases					4	43					0	0	0.217242	0	0
TBX5	6910	broad.mit.edu	37	12	114793348	114793348	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr12:114793348C>T	uc001tvo.2	-	9	2041	c.1546G>A	c.(1546-1548)GAC>AAC	p.D516N	TBX5_uc001tvp.2_Missense_Mutation_p.D516N|TBX5_uc001tvq.2_Missense_Mutation_p.D466N	NM_181486	NP_852259	Q99593	TBX5_HUMAN	T-box 5 isoform 1	516				PRTLSPHQYHSVHGVGMVPEWSDNS -> QGLYPLISTTLC TELAWCRVERQ (in Ref. 1; CAA70592).	cardiac left ventricle formation|cell migration involved in coronary vasculogenesis|cell-cell signaling|embryonic arm morphogenesis|induction of apoptosis|negative regulation of cardiac muscle cell proliferation|negative regulation of cell migration|negative regulation of epithelial to mesenchymal transition|pericardium development|positive regulation of cardioblast differentiation|positive regulation of transcription from RNA polymerase II promoter|ventricular septum development	cytoplasm|nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding			ovary(6)|pancreas(1)|skin(1)	8	Medulloblastoma(191;0.163)|all_neural(191;0.178)			BRCA - Breast invasive adenocarcinoma(302;0.0893)		TAGCTATTGTCGCTCCACTCT	0.418000													7	45					0	0	0.307466	0	0
TRPM1	4308	broad.mit.edu	37	15	31359319	31359319	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr15:31359319C>T	uc001zfm.2	-	5	627	c.499G>A	c.(499-501)GGA>AGA	p.G167R	TRPM1_uc010azy.2_Missense_Mutation_p.G80R|TRPM1_uc001zfl.2_RNA|uc010ubm.1_5'Flank|MIR211_hsa-mir-211|MI0000287_5'Flank|uc010ubn.1_5'Flank	NM_002420	NP_002411	Q7Z4N2	TRPM1_HUMAN	transient receptor potential cation channel,	167	Extracellular (Potential).				cellular response to light stimulus|visual perception	integral to plasma membrane	calcium channel activity|receptor activity			ovary(2)|pancreas(1)|skin(1)	4		all_lung(180;1.92e-11)		all cancers(64;3.52e-16)|Epithelial(43;1.65e-11)|GBM - Glioblastoma multiforme(186;3.57e-05)|BRCA - Breast invasive adenocarcinoma(123;0.00533)|COAD - Colon adenocarcinoma(236;0.0609)|Lung(196;0.199)		GGAGCAATTCCTATAGCACAA	0.448000													44	57					0	0	0.870114	0	0
SPPL2A	84888	broad.mit.edu	37	15	51017471	51017471	+	Missense_Mutation	SNP	C	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr15:51017471C>G	uc001zyv.2	-	12	1376	c.1196G>C	c.(1195-1197)AGT>ACT	p.S399T		NM_032802	NP_116191	Q8TCT8	PSL2_HUMAN	signal peptide peptidase-like 2A	399						integral to membrane	aspartic-type endopeptidase activity				0				all cancers(107;0.000712)|GBM - Glioblastoma multiforme(94;0.00314)		GAGGCACACACTCATTACTGA	0.274000													36	79					0	0	0.870114	0	0
TPM1	7168	broad.mit.edu	37	15	63336271	63336271	+	Missense_Mutation	SNP	G	A	A	rs104894505		TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr15:63336271G>A	uc002alg.2	+	2	351	c.160G>A	c.(160-162)GAA>AAA	p.E54K	TPM1_uc002alh.2_Missense_Mutation_p.E54K|TPM1_uc010bgn.2_RNA|TPM1_uc002ali.2_Missense_Mutation_p.E54K|TPM1_uc002alj.2_Intron|TPM1_uc002alk.2_Missense_Mutation_p.E54K|TPM1_uc002all.2_Intron|TPM1_uc002alm.2_Missense_Mutation_p.E96K|TPM1_uc010uie.1_Intron|TPM1_uc002alp.2_Missense_Mutation_p.E54K	NM_001018005	NP_001018005	P09493	TPM1_HUMAN	tropomyosin 1 alpha chain isoform 1	54	By similarity.		E -> K (in CMD1Y).		cardiac muscle contraction|cellular component movement|cellular response to reactive oxygen species|muscle filament sliding|negative regulation of cell migration|positive regulation of ATPase activity|positive regulation of cell adhesion|positive regulation of heart rate by epinephrine|positive regulation of stress fiber assembly|regulation of muscle contraction|ruffle organization|sarcomere organization|ventricular cardiac muscle tissue morphogenesis|wound healing	bleb|cytosol|muscle thin filament tropomyosin|ruffle membrane|stress fiber	actin binding|structural constituent of cytoskeleton|structural constituent of muscle				0						CAAGGGCACCGAAGATGAACT	0.562000													9	24					0	0	0.307466	0	0
NEO1	4756	broad.mit.edu	37	15	73428355	73428355	+	Missense_Mutation	SNP	G	C	C			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr15:73428355G>C	uc002avm.3	+	5	1144	c.1002G>C	c.(1000-1002)GAG>GAC	p.E334D	NEO1_uc010ukx.1_Missense_Mutation_p.E334D|NEO1_uc010uky.1_Missense_Mutation_p.E334D|NEO1_uc010ukz.1_5'UTR|NEO1_uc002avn.3_5'UTR	NM_002499	NP_002490	Q92859	NEO1_HUMAN	neogenin homolog 1 precursor	334	Extracellular (Potential).|Ig-like C2-type 3.				axon guidance|cell adhesion|positive regulation of muscle cell differentiation	Golgi apparatus|integral to plasma membrane|nucleus				pancreas(1)	1						CTCAAGCAGAGCTTACAGTGC	0.368000													11	23					0	0	0.500413	0	0
SPATA22	84690	broad.mit.edu	37	17	3366004	3366004	+	Missense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr17:3366004G>A	uc002fvm.2	-	4	467	c.230C>T	c.(229-231)ACC>ATC	p.T77I	SPATA22_uc010vrg.1_Missense_Mutation_p.T61I|SPATA22_uc010vrf.1_Missense_Mutation_p.T77I|SPATA22_uc002fvn.2_Missense_Mutation_p.T77I|SPATA22_uc002fvo.2_Missense_Mutation_p.T77I|SPATA22_uc002fvp.2_Missense_Mutation_p.T77I|SPATA22_uc010ckf.2_Missense_Mutation_p.T34I	NM_032598	NP_115987	Q8NHS9	SPT22_HUMAN	spermatogenesis associated 22	77											0						CACATACCCGGTGTCCACTGT	0.363000													5	113					0	0	0.248553	0	0
TCEB3C	162699	broad.mit.edu	37	18	44549150	44549150	+	Silent	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr18:44549150G>A	uc010dnr.2	-	1	1149	c.1149C>T	c.(1147-1149)GCC>GCT	p.A383A	KATNAL2_uc010dnq.1_Intron|KATNAL2_uc002lco.2_Intron|KATNAL2_uc002lcp.3_Intron	NM_001100817	NP_001094287	Q8NG57	ELOA3_HUMAN	transcription elongation factor B polypeptide	383	Activation domain (By similarity).				regulation of transcription, DNA-dependent|transcription, DNA-dependent	integral to membrane|nucleus	DNA binding				0						GAGCGAGTGCGGCATTGTCTT	0.577000													6	315					0	0	0.479597	0	0
SMAD2	4087	broad.mit.edu	37	18	45422914	45422914	+	Missense_Mutation	SNP	T	C	C			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr18:45422914T>C	uc002lcy.2	-	2	462	c.214A>G	c.(214-216)ACT>GCT	p.T72A	SMAD2_uc002lcz.2_Missense_Mutation_p.T72A|SMAD2_uc010xdc.1_Missense_Mutation_p.T72A|SMAD2_uc010xdd.1_Missense_Mutation_p.T72A	NM_005901	NP_005892	Q15796	SMAD2_HUMAN	Sma- and Mad-related protein 2 isoform 1	72	MH1.				anterior/posterior pattern formation|cell fate commitment|common-partner SMAD protein phosphorylation|intracellular signal transduction|mesoderm formation|negative regulation of transcription, DNA-dependent|palate development|paraxial mesoderm morphogenesis|positive regulation of epithelial to mesenchymal transition|positive regulation of transcription from RNA polymerase II promoter|primary miRNA processing|regulation of binding|regulation of transforming growth factor beta receptor signaling pathway|response to cholesterol|SMAD protein complex assembly|transforming growth factor beta receptor signaling pathway|zygotic specification of dorsal/ventral axis	activin responsive factor complex|cytosol	activating transcription factor binding|co-SMAD binding|double-stranded DNA binding|I-SMAD binding|R-SMAD binding|sequence-specific DNA binding transcription factor activity|transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity|type I transforming growth factor beta receptor binding|ubiquitin protein ligase binding			large_intestine(3)|lung(1)|central_nervous_system(1)	5						ACACATTTAGTATTACAGTTT	0.368000													6	70					0	0	0.307466	0	0
DAPK3	1613	broad.mit.edu	37	19	3964722	3964722	+	Silent	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr19:3964722C>T	uc002lzc.1	-	2	423	c.330G>A	c.(328-330)TCG>TCA	p.S110S	DAPK3_uc002lzb.1_5'Flank|DAPK3_uc002lzd.1_Silent_p.S110S	NM_001348	NP_001339	O43293	DAPK3_HUMAN	death-associated protein kinase 3	110	Protein kinase.				apoptosis|chromatin modification|induction of apoptosis|intracellular protein kinase cascade	cytoplasm|PML body	ATP binding|leucine zipper domain binding|protein serine/threonine kinase activity			central_nervous_system(3)|lung(2)|ovary(1)|large_intestine(1)	7		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.00461)|STAD - Stomach adenocarcinoma(1328;0.18)		CCTCCGTCAGCGACTCCTTCT	0.592000													17	110					0	0	0.520397	0	0
C3	718	broad.mit.edu	37	19	6718386	6718386	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr19:6718386C>T	uc002mfm.2	-	3	367	c.305G>A	c.(304-306)CGC>CAC	p.R102H		NM_000064	NP_000055	P01024	CO3_HUMAN	complement component 3 precursor	102					complement activation, alternative pathway|complement activation, classical pathway|G-protein coupled receptor protein signaling pathway|inflammatory response|positive regulation vascular endothelial growth factor production	extracellular space	endopeptidase inhibitor activity|receptor binding			skin(3)|ovary(1)|pancreas(1)	5				GBM - Glioblastoma multiforme(1328;1.36e-05)|Lung(535;0.00661)		GAACTTGTTGCGCCCCTTTTC	0.607000													9	122					0	0	0.335167	0	0
NOTCH3	4854	broad.mit.edu	37	19	15299837	15299837	+	Silent	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr19:15299837G>A	uc002nan.2	-	8	1417	c.1341C>T	c.(1339-1341)CTC>CTT	p.L447L	NOTCH3_uc002nao.1_Silent_p.L447L	NM_000435	NP_000426	Q9UM47	NOTC3_HUMAN	Notch homolog 3 precursor	447	Extracellular (Potential).|EGF-like 11; calcium-binding (Potential).				Notch receptor processing|Notch signaling pathway|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to membrane|nucleoplasm|plasma membrane	calcium ion binding|protein binding|receptor activity			lung(8)|ovary(5)|skin(4)|prostate(2)|central_nervous_system(1)|breast(1)	21			OV - Ovarian serous cystadenocarcinoma(3;2.6e-20)|Epithelial(3;1.34e-16)|all cancers(3;5.13e-15)			CTATGCGGTCGAGGCACGTGG	0.667000													7	31					0	0	0.307466	0	0
ZNF223	7766	broad.mit.edu	37	19	44571252	44571252	+	Missense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr19:44571252G>A	uc002oyf.1	+	5	1524	c.1271G>A	c.(1270-1272)CGA>CAA	p.R424Q	ZNF284_uc010ejd.2_RNA	NM_013361	NP_037493	Q9UK11	ZN223_HUMAN	zinc finger protein 223	424					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)	1		Prostate(69;0.0352)				CTCCATTGCCGAAAAAAACCA	0.413000													3	42					0	0	0.150653	0	0
TEAD2	8463	broad.mit.edu	37	19	49845721	49845721	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr19:49845721C>T	uc002pnj.2	-	11	1295	c.1204G>A	c.(1204-1206)GTC>ATC	p.V402I	uc002pnb.1_5'Flank|TEAD2_uc002png.2_Missense_Mutation_p.V405I|TEAD2_uc002pnh.2_Missense_Mutation_p.V406I|TEAD2_uc002pni.2_Missense_Mutation_p.V405I|TEAD2_uc010yao.1_Missense_Mutation_p.V274I|TEAD2_uc010emw.2_Missense_Mutation_p.V405I	NM_003598	NP_003589	Q15562	TEAD2_HUMAN	TEA domain family member 2	402	Transcriptional activation (Potential).				hippo signaling cascade		DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			central_nervous_system(2)|ovary(1)	3		all_lung(116;7.65e-05)|Lung NSC(112;0.000132)|all_neural(266;0.0506)|Ovarian(192;0.15)		OV - Ovarian serous cystadenocarcinoma(262;0.00093)|GBM - Glioblastoma multiforme(486;0.0467)		TTTTCCAGGACGCTGTTCATC	0.572000													26	30					0	0	0.717897	0	0
U2AF2	11338	broad.mit.edu	37	19	56175034	56175034	+	Missense_Mutation	SNP	G	C	C			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr19:56175034G>C	uc002qlu.2	+	7	1721	c.666G>C	c.(664-666)CAG>CAC	p.Q222H	U2AF2_uc002qlt.2_Missense_Mutation_p.Q222H	NM_007279	NP_009210	P26368	U2AF2_HUMAN	U2 (RNU2) small nuclear RNA auxiliary factor 2	222	RRM 1.				mRNA 3'-end processing|mRNA export from nucleus|termination of RNA polymerase II transcription	nucleoplasm|spliceosomal complex	enzyme binding|nucleotide binding|RNA binding			ovary(1)	1		Colorectal(82;0.00244)|Ovarian(87;0.133)	BRCA - Breast invasive adenocarcinoma(297;0.18)	GBM - Glioblastoma multiforme(193;0.107)		TCCAGGGCCAGTCACTAAAGA	0.567000													10	95					0	0	0.335167	0	0
THSD7B	80731	broad.mit.edu	37	2	137814593	137814593	+	Nonsense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr2:137814593G>A	uc002tva.1	+	2	650	c.650G>A	c.(649-651)TGG>TAG	p.W217*	THSD7B_uc010zbj.1_RNA|THSD7B_uc002tvb.2_Nonsense_Mutation_p.W107*	NM_001080427	NP_001073896			thrombospondin, type I, domain containing 7B											ovary(4)|central_nervous_system(2)|pancreas(1)	7				BRCA - Breast invasive adenocarcinoma(221;0.19)		GTTGGACCATGGAGTAAATGC	0.413000													37	55					0	0	0.827153	0	0
TTN	7273	broad.mit.edu	37	2	179634978	179634978	+	Missense_Mutation	SNP	C	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr2:179634978C>G	uc010zfg.1	-	36	8674	c.8450G>C	c.(8449-8451)AGT>ACT	p.S2817T	TTN_uc010zfh.1_Missense_Mutation_p.S2771T|TTN_uc010zfi.1_Missense_Mutation_p.S2771T|TTN_uc010zfj.1_Missense_Mutation_p.S2771T|TTN_uc002unb.2_Missense_Mutation_p.S2817T	NM_133378	NP_596869	Q8WZ42	TITIN_HUMAN	titin isoform N2-A	2817							ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			ovary(58)|stomach(19)|large_intestine(17)|lung(16)|skin(16)|breast(10)|pancreas(7)|kidney(4)|central_nervous_system(3)|urinary_tract(2)|upper_aerodigestive_tract(1)	153			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			ATGGGAAACACTAACTTCAAA	0.408000													8	84					0	0	0.307466	0	0
CCDC141	285025	broad.mit.edu	37	2	179720137	179720137	+	Missense_Mutation	SNP	T	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr2:179720137T>G	uc002unf.1	-	9	1329	c.1272A>C	c.(1270-1272)AAA>AAC	p.K424N		NM_173648	NP_775919	Q6ZP82	CC141_HUMAN	coiled-coil domain containing 141	424							protein binding			ovary(7)|pancreas(2)|skin(1)	10			OV - Ovarian serous cystadenocarcinoma(117;0.0274)|Epithelial(96;0.0531)|all cancers(119;0.147)			CTGTCACAACTTTGTCAAAGT	0.353000													4	35					0	0	0.150653	0	0
MYO1B	4430	broad.mit.edu	37	2	192257829	192257829	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr2:192257829C>T	uc010fsg.2	+	20	2362	c.2107C>T	c.(2107-2109)CGC>TGC	p.R703C	MYO1B_uc002usq.2_Missense_Mutation_p.R703C|MYO1B_uc002usr.2_Missense_Mutation_p.R703C|MYO1B_uc002usu.2_Translation_Start_Site	NM_001130158	NP_001123630	O43795	MYO1B_HUMAN	myosin IB isoform 1	703						myosin complex	actin binding|ATP binding|calmodulin binding|motor activity			central_nervous_system(5)|large_intestine(2)|ovary(1)	8			OV - Ovarian serous cystadenocarcinoma(117;0.0112)|Epithelial(96;0.104)|all cancers(119;0.236)			GAGGAAGCAACGCCTGGAGGA	0.413000													3	50					0	0	0.184627	0	0
IDH1	3417	broad.mit.edu	37	2	209113112	209113112	+	Missense_Mutation	SNP	C	T	T	rs121913500		TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr2:209113112C>T	uc002vcs.2	-	4	641	c.395G>A	c.(394-396)CGT>CAT	p.R132H	IDH1_uc002vct.2_Missense_Mutation_p.R132H|IDH1_uc002vcu.2_Missense_Mutation_p.R132H	NM_005896	NP_005887	O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132		Substrate.	R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(2023)|p.R132C(344)|p.R132?(210)|p.R132G(117)|p.R132S(79)|p.R132L(58)|p.R132V(1)|p.G131_R132>VL(1)		central_nervous_system(2156)|haematopoietic_and_lymphoid_tissue(606)|bone(74)|thyroid(22)|large_intestine(4)|skin(2)|prostate(2)|autonomic_ganglia(1)|soft_tissue(1)	2868				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		ATAAGCATGACGACCTATGAT	0.393000			Mis		gliobastoma 								16	49					0	0	0.557998	0	0
NGEF	25791	broad.mit.edu	37	2	233759484	233759484	+	Missense_Mutation	SNP	A	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr2:233759484A>G	uc002vts.2	-	6	1219	c.971T>C	c.(970-972)GTG>GCG	p.V324A	NGEF_uc010zmm.1_Missense_Mutation_p.V47A|NGEF_uc010fyg.1_Missense_Mutation_p.V232A|NGEF_uc002vtt.2_Missense_Mutation_p.V232A	NM_019850	NP_062824	Q8N5V2	NGEF_HUMAN	neuronal guanine nucleotide exchange factor	324	DH.				apoptosis|cell differentiation|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|nervous system development|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|growth cone|plasma membrane	Rho guanyl-nucleotide exchange factor activity			ovary(3)|central_nervous_system(3)|skin(1)	7		Breast(86;0.00279)|Renal(207;0.00339)|all_hematologic(139;0.00793)|Acute lymphoblastic leukemia(138;0.0182)|all_lung(227;0.0271)|Lung NSC(271;0.0839)		Epithelial(121;8.65e-17)|BRCA - Breast invasive adenocarcinoma(100;0.00037)|LUSC - Lung squamous cell carcinoma(224;0.00813)|Lung(119;0.00984)|GBM - Glioblastoma multiforme(43;0.0604)		GACAGCCAGCACGTCCAGGAC	0.602000													30	64					0	0	0.769981	0	0
C20orf185	359710	broad.mit.edu	37	20	31659936	31659936	+	Silent	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr20:31659936C>T	uc002wym.1	+	13	1287	c.1287C>T	c.(1285-1287)AGC>AGT	p.S429S		NM_182658	NP_872599	P59826	LPLC3_HUMAN	antimicrobial peptide RYA3 precursor	429					innate immune response	cytoplasm|extracellular region	lipid binding|protein binding			ovary(4)	4						AATGGCTCAGCCATGTGGTCG	0.532000													10	66					0	0	0.457914	0	0
COL18A1	80781	broad.mit.edu	37	21	46909433	46909433	+	Missense_Mutation	SNP	A	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr21:46909433A>G	uc011afs.1	+	18	3223	c.3202A>G	c.(3202-3204)AAG>GAG	p.K1068E	COL18A1_uc002zhg.2_Missense_Mutation_p.K653E|COL18A1_uc002zhi.2_Missense_Mutation_p.K833E	NM_130444	NP_569711	P39060	COIA1_HUMAN	alpha 1 type XVIII collagen isoform 3 precursor	1068	Triple-helical region 4 (COL4).				cell adhesion|negative regulation of cell proliferation|organ morphogenesis|visual perception	collagen|extracellular space	extracellular matrix structural constituent|metal ion binding|protein binding			central_nervous_system(1)	1				Colorectal(79;0.0157)|READ - Rectum adenocarcinoma(84;0.0929)		GCCGGGGGCGAAGGTAAGCGC	0.706000													10	10					0	0	0.361761	0	0
PARVB	29780	broad.mit.edu	37	22	44489821	44489821	+	Silent	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr22:44489821G>A	uc003ben.2	+	2	178	c.126G>A	c.(124-126)CAG>CAA	p.Q42Q	PARVB_uc003bem.2_Silent_p.Q75Q|PARVB_uc010gzn.2_5'UTR|PARVB_uc003beo.2_Silent_p.Q5Q	NM_013327	NP_037459	Q9HBI1	PARVB_HUMAN	parvin, beta isoform b	42					cell adhesion|cell junction assembly	cytoskeleton|cytosol|focal adhesion	actin binding				0		Ovarian(80;0.0246)|all_neural(38;0.0423)				GTGACCTGCAGGAAGAAGGCA	0.547000													42	84					0	0	0.870114	0	0
FLNB	2317	broad.mit.edu	37	3	58097875	58097875	+	Splice_Site	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr3:58097875G>A	uc003djj.2	+	18	2741	c.2576_splice	c.e18-1	p.G859_splice	FLNB_uc010hne.2_Splice_Site_p.G859_splice|FLNB_uc003djk.2_Splice_Site_p.G859_splice|FLNB_uc010hnf.2_Splice_Site_p.G859_splice|FLNB_uc003djl.2_Splice_Site_p.G690_splice|FLNB_uc003djm.2_Splice_Site_p.G690_splice	NM_001457	NP_001448	O75369	FLNB_HUMAN	filamin B isoform 2						actin cytoskeleton organization|cell differentiation|cytoskeletal anchoring at plasma membrane|signal transduction	cell cortex|integral to membrane|nucleus|sarcomere	actin binding			breast(8)|ovary(5)|lung(3)|skin(2)|central_nervous_system(1)	19				BRCA - Breast invasive adenocarcinoma(55;0.000335)|KIRC - Kidney renal clear cell carcinoma(284;0.0726)|Kidney(284;0.0898)		TATCTTTCCAGGTGTGGAAAA	0.522000													66	106					0	0	0.870114	0	0
CRYBG3	131544	broad.mit.edu	37	3	97596597	97596597	+	Nonsense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr3:97596597C>T	uc003drx.2	+	1	779	c.715C>T	c.(715-717)CAG>TAG	p.Q239*		NM_153605	NP_705833			beta-gamma crystallin domain containing 3												0						CCCTGATGACCAGGAGAGCGT	0.468000													10	20					0	0	0.387290	0	0
ABI3BP	25890	broad.mit.edu	37	3	100523693	100523693	+	Missense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr3:100523693G>A	uc003dun.2	-	20	1775	c.1690C>T	c.(1690-1692)CGT>TGT	p.R564C	ABI3BP_uc003duj.2_Missense_Mutation_p.R119C|ABI3BP_uc003duk.2_Missense_Mutation_p.R248C|ABI3BP_uc003dul.2_Missense_Mutation_p.R369C|ABI3BP_uc011bhd.1_Missense_Mutation_p.R518C|ABI3BP_uc003dum.2_5'UTR	NM_015429	NP_056244	Q7Z7G0	TARSH_HUMAN	ABI gene family, member 3 (NESH) binding protein	564	Pro-rich.					extracellular space				ovary(2)|large_intestine(1)|haematopoietic_and_lymphoid_tissue(1)	4						GCAGTAACACGCTGGGGCACC	0.398000													13	33					0	0	0.435327	0	0
SDHAP2	727956	broad.mit.edu	37	3	195410687	195410687	+	Missense_Mutation	SNP	T	A	A	rs6583274	by1000genomes	TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr3:195410687T>A	uc003fuw.2	+	13	1778	c.584T>A	c.(583-585)GTG>GAG	p.V195E	SDHAP2_uc003fuv.2_RNA					SubName: Full=cDNA FLJ16373 fis, clone THYMU3000269, highly similar to Succinate dehydrogenase (ubiquinone) flavoprotein subunit, mitochondrial (EC 1.3.5.1);												0						CCCTTTGAGGTGCACTGGAGG	0.567000													5	39					0	0	0.217242	0	0
SDHAP2	727956	broad.mit.edu	37	3	195410689	195410689	+	Missense_Mutation	SNP	C	T	T	rs6583275	by1000genomes	TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr3:195410689C>T	uc003fuw.2	+	13	1780	c.586C>T	c.(586-588)CAC>TAC	p.H196Y	SDHAP2_uc003fuv.2_RNA					SubName: Full=cDNA FLJ16373 fis, clone THYMU3000269, highly similar to Succinate dehydrogenase (ubiquinone) flavoprotein subunit, mitochondrial (EC 1.3.5.1);												0						CTTTGAGGTGCACTGGAGGAA	0.567000													5	39					0	0	0.217242	0	0
ENAM	10117	broad.mit.edu	37	4	71508741	71508741	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr4:71508741C>T	uc011caw.1	+	9	1879	c.1598C>T	c.(1597-1599)ACT>ATT	p.T533I		NM_031889	NP_114095	Q9NRM1	ENAM_HUMAN	enamelin precursor	533					bone mineralization|odontogenesis	proteinaceous extracellular matrix	structural constituent of tooth enamel			ovary(3)	3			Lung(101;0.235)			GAATCAGAAACTAATCAGTCA	0.413000													27	52					0	0	0.729181	0	0
NAF1	92345	broad.mit.edu	37	4	164050323	164050323	+	Missense_Mutation	SNP	T	C	C			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr4:164050323T>C	uc003iqj.2	-	8	1405	c.1211A>G	c.(1210-1212)CAG>CGG	p.Q404R	NAF1_uc010iqw.1_Intron	NM_138386	NP_612395	Q96HR8	NAF1_HUMAN	nuclear assembly factor 1 homolog isoform a	404					rRNA processing|snRNA pseudouridine synthesis	cytoplasm|nucleus|small nucleolar ribonucleoprotein complex	protein binding|snoRNA binding			ovary(2)	2	all_hematologic(180;0.166)	Prostate(90;0.109)				TGAAGTCTCCTGAGATACCAT	0.458000													9	42					0	0	0.335167	0	0
FAT1	2195	broad.mit.edu	37	4	187521295	187521295	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr4:187521295C>T	uc003izf.2	-	22	12048	c.11860G>A	c.(11860-11862)GGC>AGC	p.G3954S	FAT1_uc003ize.2_5'Flank	NM_005245	NP_005236	Q14517	FAT1_HUMAN	FAT tumor suppressor 1 precursor	3954	Extracellular (Potential).|Laminin G-like.				actin filament organization|anatomical structure morphogenesis|cell migration|cell-cell signaling|establishment or maintenance of cell polarity|homophilic cell adhesion	cell-cell junction|integral to plasma membrane|nucleus|perinuclear region of cytoplasm	calcium ion binding|protein binding			ovary(10)|central_nervous_system(1)|pancreas(1)	12						CGGATGTGGCCACCAAAAAAC	0.483000										HNSCC(5;0.00058)			5	41					0	0	0.217242	0	0
LOC100133050	100133050	broad.mit.edu	37	5	99715528	99715528	+	RNA	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr5:99715528C>T	uc011cuw.1	-	4		c.382G>A				NR_027503				Homo sapiens glucuronidase, beta pseudogene (LOC100133050), non-coding RNA.												0						AGCGGACAGTCGAAGCCCTTC	0.607000													6	21					0	0	0.248553	0	0
PCDHGA9	56107	broad.mit.edu	37	5	140783264	140783264	+	Missense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr5:140783264G>A	uc003lkh.1	+	1	745	c.745G>A	c.(745-747)GTT>ATT	p.V249I	PCDHGA1_uc003lji.1_Intron|PCDHGA2_uc003ljk.1_Intron|PCDHGA3_uc003ljm.1_Intron|PCDHGA3_uc010jfx.1_Intron|PCDHGB1_uc003ljo.1_Intron|PCDHGA4_uc003ljq.1_Intron|PCDHGB2_uc003ljs.1_Intron|PCDHGA5_uc003lju.1_Intron|PCDHGB3_uc003ljw.1_Intron|PCDHGA6_uc003ljy.1_Intron|PCDHGA7_uc003lka.1_Intron|PCDHGB4_uc003lkc.1_Intron|PCDHGA8_uc003lkd.1_Intron|PCDHGB5_uc003lkf.1_Intron|PCDHGA9_uc011dax.1_Missense_Mutation_p.V249I	NM_018921	NP_061744	Q9Y5G4	PCDG9_HUMAN	protocadherin gamma subfamily A, 9 isoform 1	249	Cadherin 3.|Extracellular (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding				0			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			GATTTACCGAGTTAAAGTCCT	0.537000													4	72					0	0	0.150653	0	0
MAML1	9794	broad.mit.edu	37	5	179192669	179192669	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr5:179192669C>T	uc003mkm.2	+	2	921	c.658C>T	c.(658-660)CCT>TCT	p.P220S	MAML1_uc003mkn.1_Missense_Mutation_p.P220S	NM_014757	NP_055572	Q92585	MAML1_HUMAN	mastermind-like 1	220					Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nuclear speck	peptide antigen binding|protein kinase binding|transcription coactivator activity			lung(4)|ovary(2)	6	all_cancers(89;0.000197)|all_epithelial(37;6.7e-05)|Renal(175;0.000159)|Lung NSC(126;0.00121)|all_lung(126;0.00218)	all_cancers(40;0.0308)|Medulloblastoma(196;0.00498)|all_neural(177;0.0138)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			GAAGCAGGAGCCTGTCGAAGA	0.517000													4	40					0	0	0.217242	0	0
NOTCH4	4855	broad.mit.edu	37	6	32166813	32166813	+	Silent	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr6:32166813G>A	uc003obb.2	-	24	4564	c.4425C>T	c.(4423-4425)CGC>CGT	p.R1475R	NOTCH4_uc011dpt.1_5'Flank|NOTCH4_uc003oba.2_Silent_p.R138R|NOTCH4_uc011dpu.1_RNA|NOTCH4_uc011dpv.1_RNA|NOTCH4_uc011dpw.1_5'Flank	NM_004557	NP_004548	Q99466	NOTC4_HUMAN	notch4 preproprotein	1475	Poly-Arg.|Cytoplasmic (Potential).				cell fate determination|embryo development|hemopoiesis|mammary gland development|negative regulation of endothelial cell differentiation|Notch receptor processing|Notch signaling pathway|patterning of blood vessels|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	cell surface|cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to plasma membrane|nucleoplasm	calcium ion binding|protein heterodimerization activity|receptor activity			lung(8)|ovary(5)|breast(4)|central_nervous_system(3)|upper_aerodigestive_tract(1)|skin(1)	22						CATGCTCTCGGCGTCGACGCC	0.667000													32	41					0	0	0.740014	0	0
NOTCH4	4855	broad.mit.edu	37	6	32190325	32190325	+	Silent	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr6:32190325C>T	uc003obb.2	-	3	553	c.414G>A	c.(412-414)TCG>TCA	p.S138S	NOTCH4_uc011dpu.1_RNA|NOTCH4_uc011dpv.1_RNA|NOTCH4_uc003obc.2_Silent_p.S138S	NM_004557	NP_004548	Q99466	NOTC4_HUMAN	notch4 preproprotein	138	EGF-like 3.|Extracellular (Potential).				cell fate determination|embryo development|hemopoiesis|mammary gland development|negative regulation of endothelial cell differentiation|Notch receptor processing|Notch signaling pathway|patterning of blood vessels|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	cell surface|cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to plasma membrane|nucleoplasm	calcium ion binding|protein heterodimerization activity|receptor activity			lung(8)|ovary(5)|breast(4)|central_nervous_system(3)|upper_aerodigestive_tract(1)|skin(1)	22						GTGGGCGGCCCGAGGCCTGGA	0.647000													5	57					0	0	0.248553	0	0
PNPLA1	285848	broad.mit.edu	37	6	36262065	36262065	+	Silent	SNP	C	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr6:36262065C>A	uc010jwf.2	+	4	603	c.603C>A	c.(601-603)CCC>CCA	p.P201P	PNPLA1_uc003olw.1_Silent_p.P106P|PNPLA1_uc010jwe.1_Silent_p.P115P	NM_001145717	NP_001139189	Q8N8W4	PLPL1_HUMAN	patatin-like phospholipase domain containing 1	201					lipid catabolic process		hydrolase activity			large_intestine(1)|pancreas(1)|breast(1)|skin(1)	4						ACATCTGTCCCCGGGACTGCC	0.607000													22	112					9.57634e-11	9.70935e-11	0.654019	1	0
PPP2R5D	5528	broad.mit.edu	37	6	42974286	42974286	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr6:42974286C>T	uc003oth.2	+	3	277	c.191C>T	c.(190-192)CCG>CTG	p.P64L	MEA1_uc010jyc.1_Intron|PPP2R5D_uc003otg.2_Missense_Mutation_p.P64L|PPP2R5D_uc010jyd.2_Intron|PPP2R5D_uc011dva.1_5'UTR|PPP2R5D_uc003oti.2_5'UTR|PPP2R5D_uc003otj.2_5'UTR	NM_006245	NP_006236	Q14738	2A5D_HUMAN	delta isoform of regulatory subunit B56, protein	64					nervous system development|signal transduction	cytoplasm|nucleus|protein phosphatase type 2A complex	protein binding|protein phosphatase type 2A regulator activity			breast(1)|central_nervous_system(1)	2			Colorectal(64;0.00237)|all cancers(41;0.00411)|COAD - Colon adenocarcinoma(64;0.00473)|OV - Ovarian serous cystadenocarcinoma(102;0.0664)|KIRC - Kidney renal clear cell carcinoma(15;0.133)|Kidney(15;0.188)			AATAGCACGCCGCCCCCCACG	0.413000													58	97					0	0	0.870114	0	0
TTBK1	84630	broad.mit.edu	37	6	43251409	43251409	+	Silent	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr6:43251409G>A	uc003ouq.1	+	14	3210	c.2931G>A	c.(2929-2931)GCG>GCA	p.A977A		NM_032538	NP_115927	Q5TCY1	TTBK1_HUMAN	tau tubulin kinase 1	977						cell junction|cytoplasm|nucleus	ATP binding|protein binding|protein serine/threonine kinase activity			lung(4)|ovary(2)|skin(2)|upper_aerodigestive_tract(1)	9			Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.0125)|OV - Ovarian serous cystadenocarcinoma(102;0.0399)			GGGCCCGAGCGCCCCTGGAGA	0.697000													25	31					0	0	0.667858	0	0
CRIP3	401262	broad.mit.edu	37	6	43275627	43275627	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr6:43275627C>T	uc010jyn.1	-	3	146	c.146G>A	c.(145-147)GGG>GAG	p.G49E	CRIP3_uc003ouu.1_Missense_Mutation_p.G49E	NM_206922	NP_996805	Q6Q6R5	CRIP3_HUMAN	cysteine-rich protein 3	49	LIM zinc-binding 1.					cytoplasm	zinc ion binding			skin(1)	1			Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.00998)|OV - Ovarian serous cystadenocarcinoma(102;0.0305)			GTATGGCCTCCCATTGTGCTG	0.607000													3	30					0	0	0.184627	0	0
TFAP2D	83741	broad.mit.edu	37	6	50681705	50681705	+	Translation_Start_Site	SNP	T	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr6:50681705T>G	uc003paf.2	+	1	449	c.-63T>G	c.(-65--61)ATTTT>ATGTT		TFAP2D_uc011dwt.1_RNA	NM_172238	NP_758438	Q7Z6R9	AP2D_HUMAN	transcription factor AP-2 beta-like 1								DNA binding|sequence-specific DNA binding transcription factor activity			ovary(6)|breast(1)	7	Lung NSC(77;0.0334)					AAGTTTGGATTTTTTTTTCCC	0.378000													15	24					0	0	0.500413	0	0
ZNF292	23036	broad.mit.edu	37	6	87943087	87943087	+	Missense_Mutation	SNP	A	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr6:87943087A>G	uc003plm.3	+	5	624	c.583A>G	c.(583-585)AGA>GGA	p.R195G		NM_015021	NP_055836	O60281	ZN292_HUMAN	zinc finger protein 292	195					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(4)	4		all_cancers(76;3.82e-09)|Prostate(29;1.34e-10)|Acute lymphoblastic leukemia(125;2.17e-10)|all_hematologic(105;1.08e-06)|all_epithelial(107;5.31e-05)		BRCA - Breast invasive adenocarcinoma(108;0.0199)		GTTGGATATGAGAATTAAACA	0.308000													8	21					0	0	0.307466	0	0
RUNX1T1	862	broad.mit.edu	37	8	92972658	92972658	+	Missense_Mutation	SNP	C	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr8:92972658C>G	uc003yfd.2	-	11	1711	c.1627G>C	c.(1627-1629)GAC>CAC	p.D543H	RUNX1T1_uc003yfc.1_Missense_Mutation_p.D516H|RUNX1T1_uc003yfe.1_Missense_Mutation_p.D506H|RUNX1T1_uc010mao.2_Missense_Mutation_p.D516H|RUNX1T1_uc011lgi.1_Missense_Mutation_p.D554H|uc010mam.2_5'Flank|RUNX1T1_uc010man.1_Missense_Mutation_p.D168H|RUNX1T1_uc003yfb.1_Missense_Mutation_p.D506H	NM_175634	NP_783552	Q06455	MTG8_HUMAN	acute myelogenous leukemia 1 translocation 1	543	MYND-type.				generation of precursor metabolites and energy	nucleus	DNA binding|protein binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			lung(9)|large_intestine(3)|breast(2)|central_nervous_system(1)|pancreas(1)	16			BRCA - Breast invasive adenocarcinoma(11;0.0141)			TTCTCCCAGTCTTTGTGCTGG	0.567000													9	36					0	0	0.335167	0	0
PLEC	5339	broad.mit.edu	37	8	144995732	144995732	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr8:144995732C>T	uc003zaf.1	-	32	8838	c.8668G>A	c.(8668-8670)GCT>ACT	p.A2890T	PLEC_uc003zab.1_Missense_Mutation_p.A2753T|PLEC_uc003zac.1_Missense_Mutation_p.A2757T|PLEC_uc003zad.2_Missense_Mutation_p.A2753T|PLEC_uc003zae.1_Missense_Mutation_p.A2721T|PLEC_uc003zag.1_Missense_Mutation_p.A2731T|PLEC_uc003zah.2_Missense_Mutation_p.A2739T|PLEC_uc003zaj.2_Missense_Mutation_p.A2780T	NM_201380	NP_958782	Q15149	PLEC_HUMAN	plectin isoform 1	2890	Globular 2.|Plectin 2.				cellular component disassembly involved in apoptosis|hemidesmosome assembly	cytosol|focal adhesion|hemidesmosome|intermediate filament cytoskeleton|sarcolemma	actin binding|structural constituent of muscle|structural constituent of muscle			large_intestine(2)|ovary(2)|pancreas(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)|skin(1)	9						TCCTTCACAGCCTCGTTGACG	0.687000													26	36					0	0	0.729181	0	0
GNE	10020	broad.mit.edu	37	9	36249251	36249251	+	Silent	SNP	G	A	A	rs147290887		TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr9:36249251G>A	uc010mlh.2	-	2	317	c.102C>T	c.(100-102)ACC>ACT	p.T34T	CLTA_uc003zzf.1_Intron|GNE_uc010mlg.2_Silent_p.T34T|GNE_uc011lpl.1_Intron|GNE_uc010mli.2_Silent_p.T65T|GNE_uc010mlj.2_Intron	NM_005476	NP_005467	Q9Y223	GLCNE_HUMAN	UDP-N-acetylglucosamine-2-epimerase/N-	34	UDP-N-acetylglucosamine 2-epimerase.				cell adhesion|lipopolysaccharide biosynthetic process|N-acetylneuraminate metabolic process|UDP-N-acetylglucosamine metabolic process		ATP binding|N-acylmannosamine kinase activity|UDP-N-acetylglucosamine 2-epimerase activity				0			STAD - Stomach adenocarcinoma(86;0.228)			ACTCAGGTTCGGTTTTAATGC	0.388000													8	52					0	0	0.307466	0	0
TBC1D2	55357	broad.mit.edu	37	9	100965580	100965580	+	Missense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr9:100965580G>A	uc011lvb.1	-	10	2441	c.2261C>T	c.(2260-2262)ACG>ATG	p.T754M	TBC1D2_uc004ayp.2_Missense_Mutation_p.T294M|TBC1D2_uc004ayq.2_Missense_Mutation_p.T754M|TBC1D2_uc004ayr.2_Missense_Mutation_p.T536M|TBC1D2_uc004ayo.3_Missense_Mutation_p.T754M	NM_018421	NP_060891	Q9BYX2	TBD2A_HUMAN	TBC1 domain family, member 2	754	Rab-GAP TBC.					cell junction|cytoplasmic membrane-bounded vesicle|nucleus	Rab GTPase activator activity			ovary(3)	3		Myeloproliferative disorder(762;0.0255)		OV - Ovarian serous cystadenocarcinoma(323;2.55e-37)		CTGGGATGCCGTCAGCGTGTT	0.587000													5	157					0	0	0.217242	0	0
FPGS	2356	broad.mit.edu	37	9	130570869	130570869	+	Silent	SNP	C	G	G			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr9:130570869C>G	uc004bsg.1	+	10	905	c.855C>G	c.(853-855)GCC>GCG	p.A285A	FPGS_uc004bsh.1_Silent_p.A102A|FPGS_uc011mal.1_Silent_p.A259A|FPGS_uc004bsi.1_Silent_p.A235A	NM_004957	NP_004948	Q05932	FOLC_HUMAN	folylpolyglutamate synthase isoform a precursor	285					folic acid metabolic process|nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|one-carbon metabolic process	cytosol|mitochondrial matrix	ATP binding|tetrahydrofolylpolyglutamate synthase activity				0					L-Glutamic Acid(DB00142)	TGCTGGAGGCCCTCGAGGAAG	0.687000													17	20					0	0	0.575678	0	0
NOTCH1	4851	broad.mit.edu	37	9	139412597	139412597	+	Missense_Mutation	SNP	C	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr9:139412597C>A	uc004chz.2	-	7	1247	c.1247G>T	c.(1246-1248)TGC>TTC	p.C416F		NM_017617	NP_060087	P46531	NOTC1_HUMAN	notch1 preproprotein	416	Extracellular (Potential).|EGF-like 11; calcium-binding (Potential).				aortic valve morphogenesis|immune response|negative regulation of BMP signaling pathway|negative regulation of cell-substrate adhesion|negative regulation of myoblast differentiation|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-dependent|Notch receptor processing	cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to membrane|nucleoplasm|plasma membrane	calcium ion binding|protein binding|receptor activity			haematopoietic_and_lymphoid_tissue(791)|upper_aerodigestive_tract(29)|lung(13)|central_nervous_system(10)|breast(9)|large_intestine(1)|skin(1)|oesophagus(1)|pancreas(1)	856	all_cancers(76;0.223)	Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;5.34e-06)|Epithelial(140;7.77e-06)		ACCCAGCGAGCACTCATCCAC	0.672000			T|Mis|O	TRB@	T-ALL					HNSCC(8;0.001)			6	6					5.68852e-11	5.84876e-11	0.307466	1	0
Unknown	0	broad.mit.edu	37	MT	7242	7242	+	Missense_Mutation	SNP	T	C	C			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chrM:7242T>C	uc011mfh.1	+	1	1389	c.341T>C	c.(340-342)ATA>ACA	p.I114T	uc004cou.3_5'Flank|uc011mfi.1_5'Flank					Homo sapiens cDNA: FLJ22894 fis, clone KAT04907.																		ACCCCGATGCATACACCACAT	0.418000													6	366					0	0	0.335167	0	0
Unknown	0	broad.mit.edu	37	MT	12514	12514	+	RNA	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chrM:12514G>A	uc004cox.3	+	1		c.178G>A			uc004coy.2_5'Flank					Homo sapiens NADH dehydrogenase subunit 5 (MTND5) mRNA, RNA 5, complete cds; mitochondrial gene for mitochondrial product.																		GCCTAGACCAAGAAGTTATTA	0.403000													7	263					0	0	0.335167	0	0
FTSJ1	24140	broad.mit.edu	37	X	48339829	48339829	+	Missense_Mutation	SNP	G	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chrX:48339829G>T	uc004djo.1	+	8	807	c.484G>T	c.(484-486)GAT>TAT	p.D162Y	FTSJ1_uc004djl.2_Missense_Mutation_p.D162Y|FTSJ1_uc004djm.2_Missense_Mutation_p.D162Y|FTSJ1_uc004djn.1_Missense_Mutation_p.D162Y|FTSJ1_uc004djp.1_Missense_Mutation_p.D162Y|FTSJ1_uc011mlw.1_Missense_Mutation_p.D25Y	NM_012280	NP_036412	Q9UET6	RRMJ1_HUMAN	FtsJ homolog 1 isoform a	162					RNA methylation|rRNA processing		methyltransferase activity|nucleic acid binding				0						CCGAGGCCGGGATGTGACGCT	0.602000													29	8					3.99451e-17	4.1657e-17	0.740014	1	0
LHFPL1	340596	broad.mit.edu	37	X	111914414	111914414	+	Missense_Mutation	SNP	G	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chrX:111914414G>A	uc004epq.2	-	2	538	c.205C>T	c.(205-207)CGC>TGC	p.R69C	LHFPL1_uc004epp.2_Missense_Mutation_p.R92C|LHFPL1_uc010nqa.2_Intron|LHFPL1_uc010nqb.2_Missense_Mutation_p.R69C	NM_178175	NP_835469	Q86WI0	LHPL1_HUMAN	lipoma HMGIC fusion partner-like 1 precursor	69						integral to membrane					0						CTGGCATAGCGCCCACATTCT	0.592000													33	61					0	0	0.779181	0	0
NSDHL	50814	broad.mit.edu	37	X	152037637	152037637	+	Missense_Mutation	SNP	C	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chrX:152037637C>T	uc004fgt.1	+	9	1360	c.1099C>T	c.(1099-1101)CGC>TGC	p.R367C	NSDHL_uc004fgs.1_Missense_Mutation_p.R367C	NM_001129765	NP_001123237	Q15738	NSDHL_HUMAN	NAD(P) dependent steroid dehydrogenase-like	367					cholesterol biosynthetic process	endoplasmic reticulum membrane|integral to membrane	3-beta-hydroxy-delta5-steroid dehydrogenase activity|binding|C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity				0	Acute lymphoblastic leukemia(192;6.56e-05)				NADH(DB00157)	GCAGAGCTTTCGCCACCTGCG	0.552000													7	21					0	0	0.361761	0	0
HFM1	164045	broad.mit.edu	37	1	91781979	91781980	+	Frame_Shift_Ins	INS	-	T	T			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr1:91781979_91781980insT	uc001doa.3	-	26	2966_2967	c.2866_2867insA	c.(2866-2868)ATAfs	p.I956fs	HFM1_uc009wdb.2_RNA|HFM1_uc010osu.1_Frame_Shift_Ins_p.I635fs|HFM1_uc001dob.3_Frame_Shift_Ins_p.I144fs|HFM1_uc010osv.1_Frame_Shift_Ins_p.I640fs	NM_001017975	NP_001017975	A2PYH4	HFM1_HUMAN	HFM1 protein	956	SEC63.						ATP binding|ATP-dependent helicase activity|nucleic acid binding				0		all_lung(203;0.00961)|Lung NSC(277;0.0351)		all cancers(265;0.000481)|Epithelial(280;0.00863)|OV - Ovarian serous cystadenocarcinoma(397;0.126)|KIRC - Kidney renal clear cell carcinoma(1967;0.171)		TGTCTCTTCTATTTTTTTAAAG	0.292													29	20	---	---	---	---					
PVRL4	81607	broad.mit.edu	37	1	161059028	161059030	+	In_Frame_Del	DEL	AGC	-	-			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr1:161059028_161059030delAGC	uc001fxo.2	-	1	356_358	c.57_59delGCT	c.(55-60)CTGCTA>CTA	p.19_20LL>L		NM_030916	NP_112178	Q96NY8	PVRL4_HUMAN	poliovirus receptor-related 4 precursor	19_20					adherens junction organization|cell adhesion|cell junction assembly	adherens junction|extracellular region|integral to membrane				ovary(2)	2	all_cancers(52;8.9e-20)|Breast(13;0.00188)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.00165)			TGCCAGCAGTAGCAGCAGCAGCA	0.512													7	227	---	---	---	---					
GLB1L2	89944	broad.mit.edu	37	11	134228963	134228988	+	Frame_Shift_Del	DEL	GACCGTGGCATTGTGGAACTGCTCCT	-	-			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr11:134228963_134228988delGACCGTGGCATTGTGGAACTGCTCCT	uc001qhp.2	+	7	849_874	c.661_686delGACCGTGGCATTGTGGAACTGCTCCT	c.(661-687)GACCGTGGCATTGTGGAACTGCTCCTGfs	p.D221fs	GLB1L2_uc009zdg.1_RNA	NM_138342	NP_612351	Q8IW92	GLBL2_HUMAN	galactosidase, beta 1-like 2 precursor	221_229					carbohydrate metabolic process	extracellular region	cation binding|hydrolase activity, hydrolyzing O-glycosyl compounds			ovary(1)|pancreas(1)|skin(1)	3	all_hematologic(175;0.127)	all_cancers(12;2.85e-18)|all_epithelial(12;1.21e-12)|all_lung(97;0.000276)|Lung NSC(97;0.000518)|Breast(109;0.00122)|Medulloblastoma(222;0.0399)|all_neural(223;0.0412)|Esophageal squamous(93;0.0844)		Epithelial(10;1.37e-11)|all cancers(11;2.2e-10)|BRCA - Breast invasive adenocarcinoma(10;3.09e-10)|OV - Ovarian serous cystadenocarcinoma(99;0.000885)|Lung(977;0.223)		GGCACTGGAGGACCGTGGCATTGTGGAACTGCTCCTGACTTCAGAC	0.606													16	204	---	---	---	---					
DHX37	57647	broad.mit.edu	37	12	125465270	125465272	+	In_Frame_Del	DEL	CTC	-	-			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr12:125465270_125465272delCTC	uc001ugy.2	-	4	601_603	c.502_504delGAG	c.(502-504)GAGdel	p.E168del		NM_032656	NP_116045	Q8IY37	DHX37_HUMAN	DEAH (Asp-Glu-Ala-His) box polypeptide 37	168							ATP binding|ATP-dependent helicase activity|nucleic acid binding|protein binding			skin(1)	1	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;8.05e-05)|Epithelial(86;0.000486)|all cancers(50;0.00653)		CCGATTCCGActcctcctcctcc	0.601													2	4	---	---	---	---					
UNC13C	440279	broad.mit.edu	37	15	54825250	54825250	+	Frame_Shift_Del	DEL	T	-	-			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr15:54825250delT	uc002ack.2	+	24	5682	c.5682delT	c.(5680-5682)GATfs	p.D1894fs		NM_001080534	NP_001074003	Q8NB66	UN13C_HUMAN	unc-13 homolog C	1894	MHD2.				exocytosis|intracellular signal transduction	cell junction|cytoplasm|presynaptic membrane	metal ion binding			ovary(5)|pancreas(2)	7				GBM - Glioblastoma multiforme(80;0.0789)|all cancers(107;0.124)		CTCTTATGGATTTTTTGGACA	0.343													2	4	---	---	---	---					
CIC	23152	broad.mit.edu	37	19	42797750	42797750	+	Frame_Shift_Del	DEL	A	-	-			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr19:42797750delA	uc002otf.1	+	16	3842	c.3802delA	c.(3802-3804)AAAfs	p.K1268fs		NM_015125	NP_055940	Q96RK0	CIC_HUMAN	capicua homolog	1268	Pro-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|protein binding			ovary(4)|breast(4)|lung(1)|central_nervous_system(1)|skin(1)	11		Prostate(69;0.00682)				CCAGGCCAGCAAATTCCCCAG	0.637			T	DUX4	soft tissue sarcoma								25	21	---	---	---	---					
ANKRD36	375248	broad.mit.edu	37	2	97808574	97808575	+	Splice_Site	INS	-	A	A			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr2:97808574_97808575insA	uc010yva.1	+	8	1145	c.901_splice	c.e8+2	p.V301_splice	ANKRD36_uc010yuz.1_Splice_Site|ANKRD36_uc010fic.2_Intron|ANKRD36_uc002sxo.2_Intron|ANKRD36_uc002sxp.3_Splice_Site	NM_001164315	NP_001157787	A6QL64	AN36A_HUMAN	ankyrin repeat domain 36												0						CTGGGACAGGTATTTTGGAATA	0.302													4	5	---	---	---	---					
KIAA1147	57189	broad.mit.edu	37	7	141362626	141362626	+	Frame_Shift_Del	DEL	T	-	-			TCGA-IK-8125-01A-11D-2253-08	TCGA-IK-8125-10A-01D-2253-08									Somatic	Phase_I	Capture				Illumina GAIIx	1a94ffa8-b014-46c2-b0fc-e2ec18aa0d03	572ef2b3-0fb8-450b-9850-765fa3c1e051	g.chr7:141362626delT	uc003vwk.2	-	9	1198	c.1198delA	c.(1198-1200)ATAfs	p.I400fs		NM_001080392	NP_001073861	A4D1U4	LCHN_HUMAN	hypothetical protein LOC57189	400										ovary(1)	1	Melanoma(164;0.0171)					GTCTGAAATATCCGGTTGTTT	0.502													10	3	---	---	---	---					
