Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	filter
SLC2A7	155184	broad.mit.edu	37	1	9074861	9074861	+	Missense_Mutation	SNP	C	T	T	rs12402973	byFrequency	TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr1:9074861C>T	uc009vmo.1	-	7	782	c.782G>A	c.(781-783)CGG>CAG	p.R261Q		NM_207420	NP_997303	Q6PXP3	GTR7_HUMAN	intestinal facilitative glucose transporter 7	261	Cytoplasmic (Potential).					integral to membrane|plasma membrane	sugar transmembrane transporter activity				0	Ovarian(185;0.112)|all_lung(157;0.185)	all_epithelial(116;1.34e-15)|all_lung(118;9.46e-05)|Lung NSC(185;0.000172)|Renal(390;0.000469)|Colorectal(325;0.0062)|Breast(348;0.00715)|Hepatocellular(190;0.0228)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.104)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;6.04e-07)|COAD - Colon adenocarcinoma(227;7.66e-05)|Kidney(185;0.000249)|KIRC - Kidney renal clear cell carcinoma(229;0.000911)|STAD - Stomach adenocarcinoma(132;0.00177)|BRCA - Breast invasive adenocarcinoma(304;0.00185)|READ - Rectum adenocarcinoma(331;0.0642)		GCGCTCGGCCCGGGCCTCCGC	0.697													7	5	---	---	---	---	PASS
UBR4	23352	broad.mit.edu	37	1	19439347	19439347	+	Silent	SNP	C	T	T	rs117673421	by1000genomes	TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr1:19439347C>T	uc001bbi.2	-	78	11476	c.11472G>A	c.(11470-11472)TCG>TCA	p.S3824S	UBR4_uc001bbj.1_3'UTR	NM_020765	NP_065816	Q5T4S7	UBR4_HUMAN	retinoblastoma-associated factor 600	3824					interspecies interaction between organisms	cytoplasm|cytoskeleton|integral to membrane|nucleus	calmodulin binding|ubiquitin-protein ligase activity|zinc ion binding			kidney(10)|ovary(7)|breast(4)|pancreas(2)|skin(2)	25		Colorectal(325;3.46e-05)|Renal(390;0.000147)|all_lung(284;0.000328)|Lung NSC(340;0.000406)|Breast(348;0.000814)|Ovarian(437;0.00774)|Myeloproliferative disorder(586;0.0256)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00674)|BRCA - Breast invasive adenocarcinoma(304;5.43e-05)|Kidney(64;0.000337)|KIRC - Kidney renal clear cell carcinoma(64;0.00426)|STAD - Stomach adenocarcinoma(196;0.00715)|READ - Rectum adenocarcinoma(331;0.0816)		ACTCTTTGCGCGAAGCAAAGA	0.413													10	332	---	---	---	---	PASS
RGS7	6000	broad.mit.edu	37	1	240977013	240977013	+	Silent	SNP	C	A	A			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr1:240977013C>A	uc001hyv.2	-	13	1191	c.861G>T	c.(859-861)ACG>ACT	p.T287T	RGS7_uc010pyh.1_Silent_p.T261T|RGS7_uc010pyj.1_Silent_p.T203T|RGS7_uc001hyu.2_Silent_p.T287T|RGS7_uc009xgn.1_Silent_p.T234T|RGS7_uc001hyw.2_Silent_p.T287T|RGS7_uc001hyt.2_Silent_p.T119T	NM_002924	NP_002915	P49802	RGS7_HUMAN	regulator of G-protein signaling 7	287	G protein gamma.				G-protein coupled receptor protein signaling pathway|intracellular signal transduction|negative regulation of signal transduction|regulation of G-protein coupled receptor protein signaling pathway	cytoplasm|heterotrimeric G-protein complex	GTPase activator activity|protein binding|signal transducer activity			ovary(4)|skin(2)|kidney(1)	7		all_cancers(173;0.0131)	OV - Ovarian serous cystadenocarcinoma(106;0.027)			AATACTGTTCCGTGTAACTTA	0.433													8	89	---	---	---	---	PASS
NCKAP1	10787	broad.mit.edu	37	2	183846059	183846059	+	Silent	SNP	A	G	G			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr2:183846059A>G	uc002upc.2	-	13	1656	c.1254T>C	c.(1252-1254)CAT>CAC	p.H418H	NCKAP1_uc002upb.2_Silent_p.H424H	NM_013436	NP_038464	Q9Y2A7	NCKP1_HUMAN	NCK-associated protein 1 isoform 1	418					apoptosis|central nervous system development	integral to membrane|lamellipodium membrane	protein binding			ovary(2)	2			OV - Ovarian serous cystadenocarcinoma(117;0.0942)|Epithelial(96;0.209)			ATTTCCTCACATGTGCTCTAA	0.328													7	109	---	---	---	---	PASS
TNS1	7145	broad.mit.edu	37	2	218683368	218683368	+	Silent	SNP	C	T	T	rs34144104	byFrequency	TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr2:218683368C>T	uc002vgt.2	-	24	3773	c.3375G>A	c.(3373-3375)CCG>CCA	p.P1125P	TNS1_uc002vgr.2_Silent_p.P1112P|TNS1_uc002vgs.2_Silent_p.P1104P|TNS1_uc010zjv.1_Silent_p.P1104P	NM_022648	NP_072174	Q9HBL0	TENS1_HUMAN	tensin	1125	Ser-rich.					cytoplasm|cytoskeleton|focal adhesion	actin binding			ovary(3)|breast(1)	4		Renal(207;0.0483)|Lung NSC(271;0.213)		Epithelial(149;4.43e-06)|all cancers(144;0.000653)|LUSC - Lung squamous cell carcinoma(224;0.0091)|Lung(261;0.013)		TCTGGGCAGACGGGCTGGGCT	0.632													4	80	---	---	---	---	PASS
CCDC140	151278	broad.mit.edu	37	2	223168894	223168894	+	Missense_Mutation	SNP	G	C	C			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr2:223168894G>C	uc002vnb.1	+	2	657	c.273G>C	c.(271-273)AAG>AAC	p.K91N		NM_153038	NP_694583	Q96MF4	CC140_HUMAN	coiled-coil domain containing 140	91											0		Renal(207;0.0376)		Epithelial(121;4.03e-10)|all cancers(144;1.8e-07)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		GCGTTTTGAAGAGTGCTGCGC	0.662													3	40	---	---	---	---	PASS
AGAP1	116987	broad.mit.edu	37	2	236708166	236708166	+	Silent	SNP	C	T	T	rs2292708	byFrequency	TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr2:236708166C>T	uc002vvs.2	+	8	1552	c.957C>T	c.(955-957)ACC>ACT	p.T319T	AGAP1_uc002vvt.2_Silent_p.T319T	NM_001037131	NP_001032208	Q9UPQ3	AGAP1_HUMAN	centaurin, gamma 2 isoform 1	319					protein transport|regulation of ARF GTPase activity|small GTPase mediated signal transduction	cytoplasm	ARF GTPase activator activity|GTP binding|zinc ion binding			ovary(2)|skin(1)	3						ACCTGTTCACCGTGAGTGTCA	0.542													4	89	---	---	---	---	PASS
BCL6	604	broad.mit.edu	37	3	187447376	187447376	+	Missense_Mutation	SNP	T	C	C	rs139857005		TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr3:187447376T>C	uc003frp.3	-	5	1274	c.817A>G	c.(817-819)ATG>GTG	p.M273V	BCL6_uc011bsf.1_Missense_Mutation_p.M273V|BCL6_uc010hza.2_Missense_Mutation_p.M171V|BCL6_uc003frq.1_Missense_Mutation_p.M273V	NM_001130845	NP_001124317	P41182	BCL6_HUMAN	B-cell lymphoma 6 protein isoform 1	273					negative regulation of B cell apoptosis|negative regulation of cell growth|negative regulation of S phase of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|positive regulation of apoptosis|protein import into nucleus, translocation|regulation of germinal center formation|response to DNA damage stimulus	nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(2)|lung(2)|central_nervous_system(1)	5	all_cancers(143;9.45e-12)|Ovarian(172;0.0418)		OV - Ovarian serous cystadenocarcinoma(80;1.76e-18)	GBM - Glioblastoma multiforme(93;0.0141)		CTGTAGTGCATATCACTTCGT	0.547			T|Mis	IG loci|ZNFN1A1|LCP1|PIM1|TFRC|MHC2TA|NACA|HSPCB|HSPCA|HIST1H4I|IL21R| POU2AF1|ARHH|EIF4A2|SFRS3	NHL|CLL								7	122	---	---	---	---	PASS
TNIP3	79931	broad.mit.edu	37	4	122075727	122075727	+	Silent	SNP	A	G	G			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr4:122075727A>G	uc010ing.2	-	5	667	c.471T>C	c.(469-471)TGT>TGC	p.C157C	TNIP3_uc010inh.2_Silent_p.C157C|TNIP3_uc011cgj.1_Silent_p.C215C|TNIP3_uc010ini.2_Silent_p.C157C	NM_024873	NP_079149	Q96KP6	TNIP3_HUMAN	TNFAIP3 interacting protein 3	157	Potential.									ovary(1)	1						GTTTTATTTCACATTCGTAAT	0.348													7	260	---	---	---	---	PASS
SNCAIP	9627	broad.mit.edu	37	5	121739540	121739540	+	Missense_Mutation	SNP	C	T	T			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr5:121739540C>T	uc003ksw.1	+	3	316	c.110C>T	c.(109-111)ACG>ATG	p.T37M	SNCAIP_uc011cwl.1_Translation_Start_Site|SNCAIP_uc010jct.2_Missense_Mutation_p.T37M|SNCAIP_uc003ksx.1_Missense_Mutation_p.T84M|SNCAIP_uc003ksy.1_Missense_Mutation_p.R22C|SNCAIP_uc003ksz.1_Missense_Mutation_p.R22C|SNCAIP_uc010jcu.2_Missense_Mutation_p.R22C|SNCAIP_uc011cwm.1_Missense_Mutation_p.R22C|SNCAIP_uc003kta.1_Missense_Mutation_p.R20C|SNCAIP_uc010jcv.1_RNA|SNCAIP_uc010jcw.1_Missense_Mutation_p.R22C|SNCAIP_uc010jcx.1_Missense_Mutation_p.T37M	NM_005460	NP_005451	Q9Y6H5	SNCAP_HUMAN	synuclein alpha interacting protein	37					cell death|dopamine metabolic process|regulation of inclusion body assembly|regulation of neurotransmitter secretion	cytoplasm|neuronal cell body|nucleolus|presynaptic membrane	ubiquitin protein ligase binding			ovary(1)|pancreas(1)	2		all_cancers(142;0.00787)|Prostate(80;0.0327)	KIRC - Kidney renal clear cell carcinoma(527;0.206)	OV - Ovarian serous cystadenocarcinoma(64;0.000625)|Epithelial(69;0.00216)|all cancers(49;0.0232)		AGATGTGATACGCAAAACGAA	0.463													12	169	---	---	---	---	PASS
TNXB	7148	broad.mit.edu	37	6	32037587	32037587	+	Missense_Mutation	SNP	C	T	T			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr6:32037587C>T	uc003nzl.2	-	15	5532	c.5330G>A	c.(5329-5331)CGT>CAT	p.R1777H		NM_019105	NP_061978	P22105	TENX_HUMAN	tenascin XB isoform 1 precursor	1859	Fibronectin type-III 11.				actin cytoskeleton organization|cell adhesion|collagen metabolic process|elastic fiber assembly|signal transduction	extracellular space|intracellular|proteinaceous extracellular matrix	heparin binding|integrin binding				0						CTCCCCCAGACGGGGTTTTGG	0.582													3	42	---	---	---	---	PASS
DAAM2	23500	broad.mit.edu	37	6	39832798	39832798	+	Missense_Mutation	SNP	A	G	G			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr6:39832798A>G	uc003oow.2	+	5	532	c.376A>G	c.(376-378)AGG>GGG	p.R126G	DAAM2_uc010jxc.2_Missense_Mutation_p.R126G|DAAM2_uc003oox.2_Missense_Mutation_p.R126G	NM_015345	NP_056160	Q86T65	DAAM2_HUMAN	dishevelled associated activator of	126	GBD/FH3.				actin cytoskeleton organization		actin binding|Rho GTPase binding			ovary(2)|skin(1)	3	Ovarian(28;0.0355)|Colorectal(47;0.196)					GACGGAGATGAGGAACCAAGT	0.557											OREG0017416	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	2	14	---	---	---	---	PASS
LOC442421	442421	broad.mit.edu	37	9	66499716	66499716	+	Missense_Mutation	SNP	A	G	G	rs141617852	by1000genomes	TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr9:66499716A>G	uc004aee.1	+	1	526	c.526A>G	c.(526-528)AAT>GAT	p.N176D	LOC442421_uc004aed.1_RNA					Homo sapiens hypothetical LOC442421, mRNA (cDNA clone IMAGE:40031134).												0						CCTGGAGCCCAATCTGCTGGA	0.607													12	118	---	---	---	---	PASS
ZER1	10444	broad.mit.edu	37	9	131503068	131503068	+	Silent	SNP	C	T	T			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr9:131503068C>T	uc004bwa.1	-	12	2269	c.1836G>A	c.(1834-1836)CAG>CAA	p.Q612Q		NM_006336	NP_006327	Q7Z7L7	ZER1_HUMAN	zyg-11 homolog B (C. elegans)-like	612	ARM 4.				ATP hydrolysis coupled proton transport|regulation of ubiquitin-protein ligase activity	Cul2-RING ubiquitin ligase complex|vacuolar proton-transporting V-type ATPase, V1 domain	protein binding|proton-transporting ATPase activity, rotational mechanism|ubiquitin-protein ligase activity			ovary(1)	1						CGCTGATGAACTGGGAAGTCA	0.308													8	166	---	---	---	---	PASS
TRIM6	117854	broad.mit.edu	37	11	5632424	5632424	+	Missense_Mutation	SNP	A	G	G			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr11:5632424A>G	uc001mbc.1	+	8	1451	c.1319A>G	c.(1318-1320)GAG>GGG	p.E440G	HBG2_uc001mak.1_Intron|TRIM6-TRIM34_uc001mbf.2_Intron|TRIM6_uc009yeo.1_Missense_Mutation_p.E414G|TRIM6_uc010qzj.1_Missense_Mutation_p.E265G|TRIM6_uc001mbe.2_Missense_Mutation_p.E265G|TRIM6_uc010qzk.1_Missense_Mutation_p.E265G|TRIM6_uc010qzl.1_Missense_Mutation_p.E265G|TRIM6_uc001mbd.2_Missense_Mutation_p.E468G|TRIM6_uc001mbg.1_Missense_Mutation_p.E265G|TRIM6_uc009yep.1_3'UTR	NM_058166	NP_477514	Q9C030	TRIM6_HUMAN	tripartite motif-containing 6 isoform 2	440	B30.2/SPRY.				protein trimerization	cytoplasm	zinc ion binding				0		Lung NSC(207;2.23e-07)|all_lung(207;1.81e-06)|Medulloblastoma(188;0.00225)|Breast(177;0.0101)|all_neural(188;0.0212)		Epithelial(150;1.12e-45)|BRCA - Breast invasive adenocarcinoma(625;0.00101)|LUSC - Lung squamous cell carcinoma(625;0.192)		TTAGATTATGAGGCTGGTACT	0.433													14	316	---	---	---	---	PASS
OR5B17	219965	broad.mit.edu	37	11	58126475	58126475	+	Missense_Mutation	SNP	A	C	C			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr11:58126475A>C	uc010rke.1	-	1	68	c.68T>G	c.(67-69)GTT>GGT	p.V23G		NM_001005489	NP_001005489	Q8NGF7	OR5BH_HUMAN	olfactory receptor, family 5, subfamily B,	23	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)|skin(1)	3	Esophageal squamous(5;0.0027)	Breast(21;0.0778)				AAAGAGGGGAACCTGTAGTTC	0.438													11	166	---	---	---	---	PASS
DRD2	1813	broad.mit.edu	37	11	113295366	113295366	+	Missense_Mutation	SNP	G	A	A			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr11:113295366G>A	uc001pnz.2	-	1	329	c.8C>T	c.(7-9)CCA>CTA	p.P3L	DRD2_uc010rwv.1_Missense_Mutation_p.P3L|DRD2_uc001poa.3_Missense_Mutation_p.P3L|DRD2_uc001pob.3_Missense_Mutation_p.P3L|DRD2_uc009yyr.1_Missense_Mutation_p.P3L	NM_000795	NP_000786	P14416	DRD2_HUMAN	dopamine receptor D2 isoform long	3	Extracellular (By similarity).				activation of phospholipase C activity by dopamine receptor signaling pathway|adenohypophysis development|adult walking behavior|arachidonic acid secretion|axonogenesis|behavioral response to cocaine|behavioral response to ethanol|branching morphogenesis of a nerve|cerebral cortex GABAergic interneuron migration|circadian regulation of gene expression|elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger|inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|intracellular protein kinase cascade|negative regulation of blood pressure|negative regulation of calcium ion transport via voltage-gated calcium channel activity|negative regulation of cell migration|negative regulation of cell proliferation|negative regulation of dopamine receptor signaling pathway|negative regulation of protein kinase B signaling cascade|negative regulation of protein secretion|negative regulation of synaptic transmission, glutamatergic|neurological system process involved in regulation of systemic arterial blood pressure|peristalsis|phosphatidylinositol metabolic process|positive regulation of dopamine uptake|positive regulation of growth hormone secretion|positive regulation of neuroblast proliferation|prepulse inhibition|protein localization|regulation of heart rate|regulation of long-term neuronal synaptic plasticity|regulation of potassium ion transport|regulation of sodium ion transport|regulation of synaptic transmission, GABAergic|release of sequestered calcium ion into cytosol|response to amphetamine|response to drug|response to histamine|response to morphine|sensory perception of smell|synapse assembly|temperature homeostasis|visual learning	integral to plasma membrane	dopamine D2 receptor activity|dopamine receptor activity, coupled via Gi/Go|drug binding|potassium channel regulator activity|protein binding			pancreas(1)|skin(1)	2		all_cancers(61;3.91e-16)|all_epithelial(67;2.95e-09)|Melanoma(852;1.46e-05)|all_hematologic(158;0.00014)|Acute lymphoblastic leukemia(157;0.000977)|Breast(348;0.0101)|all_neural(223;0.0281)|Medulloblastoma(222;0.0425)|Prostate(24;0.0494)		BRCA - Breast invasive adenocarcinoma(274;5.77e-06)|Epithelial(105;6.66e-05)|all cancers(92;0.000307)|OV - Ovarian serous cystadenocarcinoma(223;0.216)	Acetophenazine(DB01063)|Amantadine(DB00915)|Apomorphine(DB00714)|Aripiprazole(DB01238)|Bromocriptine(DB01200)|Buspirone(DB00490)|Cabergoline(DB00248)|Carphenazine(DB01038)|Chlorpromazine(DB00477)|Chlorprothixene(DB01239)|Cinnarizine(DB00568)|Clozapine(DB00363)|Domperidone(DB01184)|Droperidol(DB00450)|Ergotamine(DB00696)|Flupenthixol(DB00875)|Fluphenazine(DB00623)|Fluspirilene(DB04842)|Haloperidol(DB00502)|Levodopa(DB01235)|Lisuride(DB00589)|Loxapine(DB00408)|Mesoridazine(DB00933)|Metoclopramide(DB01233)|Minaprine(DB00805)|Molindone(DB01618)|Olanzapine(DB00334)|Paliperidone(DB01267)|Pergolide(DB01186)|Perphenazine(DB00850)|Pimozide(DB01100)|Pramipexole(DB00413)|Prochlorperazine(DB00433)|Promazine(DB00420)|Promethazine(DB01069)|Propiomazine(DB00777)|Quetiapine(DB01224)|Remoxipride(DB00409)|Risperidone(DB00734)|Ropinirole(DB00268)|Sertindole(DB06144)|Sulpiride(DB00391)|Thiethylperazine(DB00372)|Thioridazine(DB00679)|Tranylcypromine(DB00752)|Trifluoperazine(DB00831)|Triflupromazine(DB00508)|Ziprasidone(DB00246)|Zuclopenthixol(DB01624)	CAGATTCAGTGGATCCATCAG	0.582													4	79	---	---	---	---	PASS
LRIG3	121227	broad.mit.edu	37	12	59267899	59267899	+	Missense_Mutation	SNP	G	A	A			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr12:59267899G>A	uc001sqr.2	-	18	3299	c.3053C>T	c.(3052-3054)TCC>TTC	p.S1018F	LRIG3_uc009zqh.2_Missense_Mutation_p.S958F|LRIG3_uc010ssh.1_RNA	NM_153377	NP_700356	Q6UXM1	LRIG3_HUMAN	leucine-rich repeats and immunoglobulin-like	1018						integral to membrane				skin(3)|ovary(1)	4			GBM - Glioblastoma multiforme(1;1.17e-18)			ATCTAAAGAGGACTTGTTTAG	0.403													11	219	---	---	---	---	PASS
MED13L	23389	broad.mit.edu	37	12	116446661	116446661	+	Silent	SNP	C	A	A			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr12:116446661C>A	uc001tvw.2	-	10	1612	c.1557G>T	c.(1555-1557)GTG>GTT	p.V519V		NM_015335	NP_056150	Q71F56	MD13L_HUMAN	mediator complex subunit 13-like	519					regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent					skin(4)|ovary(2)|upper_aerodigestive_tract(1)|lung(1)	8	all_neural(191;0.117)|Medulloblastoma(191;0.163)			BRCA - Breast invasive adenocarcinoma(302;0.0407)		TACTGCTAGACACCTCTAAGG	0.453													7	97	---	---	---	---	PASS
P2RX2	22953	broad.mit.edu	37	12	133197607	133197607	+	Silent	SNP	T	C	C			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr12:133197607T>C	uc001ukj.1	+	8	795	c.795T>C	c.(793-795)ATT>ATC	p.I265I	P2RX2_uc001uki.1_Silent_p.I265I|P2RX2_uc001ukk.1_Silent_p.I265I|P2RX2_uc001ukl.1_Silent_p.I241I|P2RX2_uc001ukm.1_Silent_p.I193I|P2RX2_uc001ukn.1_Silent_p.I173I|P2RX2_uc009zyt.1_Silent_p.I265I|P2RX2_uc001uko.1_Silent_p.I231I	NM_170682	NP_733782	Q9UBL9	P2RX2_HUMAN	purinergic receptor P2X2 isoform A	265	Extracellular (Potential).				positive regulation of calcium ion transport into cytosol|positive regulation of calcium-mediated signaling|protein homooligomerization	integral to membrane	ATP binding|extracellular ATP-gated cation channel activity|identical protein binding|purinergic nucleotide receptor activity				0	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.0767)		OV - Ovarian serous cystadenocarcinoma(86;2.32e-08)|Epithelial(86;8.62e-08)|all cancers(50;4.5e-06)		TCGGGGTCATTATCAACTGGG	0.637													5	84	---	---	---	---	PASS
TPTE2	93492	broad.mit.edu	37	13	20006719	20006719	+	Splice_Site	SNP	C	G	G	rs143769638		TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr13:20006719C>G	uc001umd.2	-	17	1328	c.1117_splice	c.e17-1	p.N373_splice	TPTE2_uc009zzk.2_Splice_Site|TPTE2_uc009zzl.2_Splice_Site_p.N262_splice|TPTE2_uc001ume.2_Splice_Site_p.N296_splice|TPTE2_uc009zzm.2_Splice_Site_p.N44_splice|TPTE2_uc010tcm.1_Splice_Site|TPTE2_uc010tcl.1_Splice_Site_p.N44_splice	NM_199254	NP_954863	Q6XPS3	TPTE2_HUMAN	TPTE and PTEN homologous inositol lipid							endoplasmic reticulum membrane|integral to membrane	ion channel activity|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity				0		all_cancers(29;1.23e-20)|all_lung(29;1.97e-20)|all_epithelial(30;5.86e-20)|Lung NSC(5;3.36e-17)|Lung SC(185;0.0262)|Ovarian(182;0.162)		all cancers(112;1.73e-05)|Epithelial(112;7.42e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.000785)|Lung(94;0.0176)|LUSC - Lung squamous cell carcinoma(192;0.089)		CATATCTATTCTGAAAAGCAA	0.313													6	81	---	---	---	---	PASS
MTHFD1	4522	broad.mit.edu	37	14	64909059	64909059	+	Missense_Mutation	SNP	C	G	G			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr14:64909059C>G	uc001xhb.2	+	21	2462	c.2075C>G	c.(2074-2076)CCC>CGC	p.P692R	MTHFD1_uc010aqf.2_Missense_Mutation_p.P748R	NM_005956	NP_005947	P11586	C1TC_HUMAN	methylenetetrahydrofolate dehydrogenase 1	692	Formyltetrahydrofolate synthetase.				folic acid metabolic process|folic acid-containing compound biosynthetic process|histidine biosynthetic process|methionine biosynthetic process|one-carbon metabolic process|purine nucleotide biosynthetic process	cytosol|mitochondrion	ATP binding|formate-tetrahydrofolate ligase activity|methenyltetrahydrofolate cyclohydrolase activity|methylenetetrahydrofolate dehydrogenase (NADP+) activity|methylenetetrahydrofolate dehydrogenase|protein binding			ovary(2)	2				OV - Ovarian serous cystadenocarcinoma(108;8.7e-12)|all cancers(60;3.29e-11)|BRCA - Breast invasive adenocarcinoma(234;0.0488)	NADH(DB00157)|Tetrahydrofolic acid(DB00116)	GGCCTCTGCCCCCACGTGGTG	0.527													5	154	---	---	---	---	PASS
AK7	122481	broad.mit.edu	37	14	96909069	96909069	+	Missense_Mutation	SNP	G	A	A			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr14:96909069G>A	uc001yfn.2	+	7	737	c.693G>A	c.(691-693)ATG>ATA	p.M231I		NM_152327	NP_689540	Q96M32	KAD7_HUMAN	adenylate kinase 7	231	Potential.				cell projection organization	cytosol	adenylate kinase activity|ATP binding|cytidylate kinase activity			ovary(1)	1		all_cancers(154;0.0482)|all_epithelial(191;0.128)|Melanoma(154;0.155)		Epithelial(152;0.134)|COAD - Colon adenocarcinoma(157;0.228)		CCTTTCAGATGGCTTGGTTGG	0.443													13	402	---	---	---	---	PASS
SLC7A5P2	387254	broad.mit.edu	37	16	21531609	21531609	+	Missense_Mutation	SNP	C	T	T	rs42139	by1000genomes	TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr16:21531609C>T	uc002djd.2	-	1	157	c.78G>A	c.(76-78)ATG>ATA	p.M26I	uc002diq.3_Intron|LOC100271836_uc002dja.2_RNA|LOC100271836_uc002djb.2_RNA	NR_002594				RecName: Full=Putative L-type amino acid transporter 1-like protein MLAS; AltName: Full=hLAT1 3-transmembrane protein MLAS;          Short=hLAT1 3TM MLAS;												0						TGGCGGCCATCATCTTCTCCC	0.741													4	8	---	---	---	---	PASS
UBTF	7343	broad.mit.edu	37	17	42293143	42293143	+	Missense_Mutation	SNP	G	A	A			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr17:42293143G>A	uc002igb.2	-	4	420	c.353C>T	c.(352-354)CCT>CTT	p.P118L	UBTF_uc002igc.2_Missense_Mutation_p.P118L|UBTF_uc010czs.2_Missense_Mutation_p.P118L|UBTF_uc002igd.2_Missense_Mutation_p.P118L|UBTF_uc010czt.2_Missense_Mutation_p.P118L|UBTF_uc002ige.2_Missense_Mutation_p.P118L	NM_014233	NP_055048	P17480	UBF1_HUMAN	upstream binding transcription factor, RNA	118	HMG box 1.				positive regulation of transcription from RNA polymerase I promoter|termination of RNA polymerase I transcription|transcription elongation from RNA polymerase I promoter|transcription initiation from RNA polymerase I promoter	nucleolus|nucleoplasm	DNA binding|protein binding				0		Breast(137;0.00765)|Prostate(33;0.0181)		BRCA - Breast invasive adenocarcinoma(366;0.114)		GCGGAAATAAGGGGTCAGGGG	0.488													7	162	---	---	---	---	PASS
SGSH	6448	broad.mit.edu	37	17	78188012	78188012	+	Missense_Mutation	SNP	G	T	T			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr17:78188012G>T	uc002jxz.3	-	5	709	c.622C>A	c.(622-624)CCA>ACA	p.P208T	SGSH_uc002jya.3_Missense_Mutation_p.P5T|SGSH_uc002jxy.2_Missense_Mutation_p.P208T|SGSH_uc010wue.1_Silent_p.S219S	NM_000199	NP_000190	P51688	SPHM_HUMAN	N-sulfoglucosamine sulfohydrolase precursor	208					proteoglycan metabolic process	lysosome	metal ion binding|N-sulfoglucosamine sulfohydrolase activity|sulfuric ester hydrolase activity			ovary(1)|central_nervous_system(1)	2	all_neural(118;0.0952)		OV - Ovarian serous cystadenocarcinoma(97;0.0292)|BRCA - Breast invasive adenocarcinoma(99;0.0908)			GTCCAGTCTGGGATACGACCC	0.667													4	31	---	---	---	---	PASS
ZNF441	126068	broad.mit.edu	37	19	11892189	11892189	+	Missense_Mutation	SNP	C	T	T			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr19:11892189C>T	uc010dyj.2	+	4	1744	c.1550C>T	c.(1549-1551)TCA>TTA	p.S517L	ZNF441_uc002msn.3_Missense_Mutation_p.S473L	NM_152355	NP_689568	Q8N8Z8	ZN441_HUMAN	zinc finger protein 441	517	C2H2-type 13.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)	1						TCTCCCAGTTCATTTCGAAGA	0.398													8	160	---	---	---	---	PASS
SCAF1	58506	broad.mit.edu	37	19	50158050	50158050	+	Missense_Mutation	SNP	A	C	C			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr19:50158050A>C	uc002poq.2	+	9	3665	c.3541A>C	c.(3541-3543)ACC>CCC	p.T1181P		NM_021228	NP_067051	Q9H7N4	SFR19_HUMAN	SR-related CTD-associated factor 1	1181					mRNA processing|RNA splicing	nucleus	RNA binding				0		all_lung(116;1.05e-05)|Lung NSC(112;3.77e-05)|all_neural(266;0.196)|Ovarian(192;0.231)		OV - Ovarian serous cystadenocarcinoma(262;0.00113)|GBM - Glioblastoma multiforme(134;0.0204)		GACCCCCCCCACCCCCACCGG	0.692													4	23	---	---	---	---	PASS
PRIC285	85441	broad.mit.edu	37	20	62193019	62193019	+	Silent	SNP	C	T	T	rs11551684	byFrequency	TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr20:62193019C>T	uc002yfm.2	-	13	7663	c.6771G>A	c.(6769-6771)CCG>CCA	p.P2257P	PRIC285_uc002yfl.1_Silent_p.P1688P	NM_001037335	NP_001032412	Q9BYK8	PR285_HUMAN	PPAR-alpha interacting complex protein 285	2257					cellular lipid metabolic process|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleoplasm	ATP binding|DNA binding|helicase activity|ribonuclease activity|RNA binding|transcription coactivator activity|zinc ion binding			central_nervous_system(2)	2	all_cancers(38;2.51e-11)|all_epithelial(29;8.27e-13)		Epithelial(9;1.27e-08)|all cancers(9;7.32e-08)|BRCA - Breast invasive adenocarcinoma(10;5.15e-06)			TGCCCACACGCGGCACTGGGA	0.652													6	104	---	---	---	---	PASS
C22orf29	79680	broad.mit.edu	37	22	19838698	19838698	+	Missense_Mutation	SNP	C	G	G			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr22:19838698C>G	uc002zqg.2	-	2	1686	c.1087G>C	c.(1087-1089)GGG>CGG	p.G363R	GNB1L_uc002zqd.1_Intron|GNB1L_uc002zqe.1_Intron|GNB1L_uc002zqf.1_Intron|C22orf29_uc002zqh.2_Missense_Mutation_p.G363R|C22orf29_uc002zqi.2_Missense_Mutation_p.G363R|C22orf29_uc010grt.1_Intron	NM_024627	NP_078903	Q7L3V2	CV029_HUMAN	hypothetical protein LOC79680	363											0	Colorectal(54;0.0993)					GTTCAGAACCCAGGAGAAAGT	0.607													2	8	---	---	---	---	PASS
PKDREJ	10343	broad.mit.edu	37	22	46657040	46657040	+	Missense_Mutation	SNP	C	T	T			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr22:46657040C>T	uc003bhh.2	-	1	2180	c.2180G>A	c.(2179-2181)CGA>CAA	p.R727Q		NM_006071	NP_006062	Q9NTG1	PKDRE_HUMAN	receptor for egg jelly-like protein precursor	727	Extracellular (Potential).|REJ.				acrosome reaction|neuropeptide signaling pathway	integral to membrane	calcium ion binding|ion channel activity			breast(3)|ovary(2)	5		Ovarian(80;0.00965)|all_neural(38;0.0416)		UCEC - Uterine corpus endometrioid carcinoma (28;0.00459)		TCTGTCATCTCGGAGAGGTAA	0.388													6	209	---	---	---	---	PASS
FOXP1	27086	broad.mit.edu	37	3	71027051	71027051	+	Frame_Shift_Del	DEL	T	-	-			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr3:71027051delT	uc003dol.2	-	11	1599	c.1276delA	c.(1276-1278)ACCfs	p.T426fs	FOXP1_uc003dom.2_Frame_Shift_Del_p.T350fs|FOXP1_uc003don.2_RNA|FOXP1_uc003doo.2_Frame_Shift_Del_p.T426fs|FOXP1_uc003dop.2_Frame_Shift_Del_p.T426fs|FOXP1_uc003doq.1_Frame_Shift_Del_p.T425fs|FOXP1_uc003doi.2_Frame_Shift_Del_p.T326fs|FOXP1_uc003doj.2_Frame_Shift_Del_p.T326fs|FOXP1_uc003dok.2_Frame_Shift_Del_p.T239fs|FOXP1_uc003dor.1_Frame_Shift_Del_p.T204fs	NM_032682	NP_116071	Q9H334	FOXP1_HUMAN	forkhead box P1 isoform 1	426					cardiac muscle cell differentiation|embryo development|immunoglobulin V(D)J recombination|pattern specification process|positive regulation of epithelial cell proliferation involved in lung morphogenesis|positive regulation of immunoglobulin production|positive regulation of mesenchymal cell proliferation|pre-B cell differentiation|regulation of sequence-specific DNA binding transcription factor activity|skeletal muscle tissue development|smooth muscle tissue development	cytoplasm|transcription factor complex	chromatin binding|DNA bending activity|double-stranded DNA binding|promoter binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|zinc ion binding			ovary(1)|lung(1)	2		Lung NSC(201;4.62e-05)|Prostate(10;0.0181)|Hepatocellular(537;0.186)|Myeloproliferative disorder(1037;0.209)		BRCA - Breast invasive adenocarcinoma(55;1.17e-05)|Epithelial(33;1.39e-05)|LUSC - Lung squamous cell carcinoma(21;2.35e-05)|Lung(16;4.26e-05)		ATGCTGGTGGTTGTGATGACA	0.577			T	PAX5	ALL								265	11	---	---	---	---	
MED1	5469	broad.mit.edu	37	17	37566389	37566390	+	Frame_Shift_Del	DEL	TA	-	-			TCGA-CH-5763-01A-11D-1576-08	TCGA-CH-5763-11A-01D-1576-08									Somatic	Phase_I	Capture				Illumina GAIIx	581be6cf-9778-49c3-9c77-1316eaa78929	b3c65fbf-e781-4a0c-b76d-8a6c4535ccef	g.chr17:37566389_37566390delTA	uc002hrv.3	-	17	2296_2297	c.2084_2085delTA	c.(2083-2085)TTAfs	p.L695fs	MED1_uc010wee.1_Frame_Shift_Del_p.L523fs|MED1_uc002hru.2_Intron	NM_004774	NP_004765	Q15648	MED1_HUMAN	mediator complex subunit 1	695	Interaction with PPARGC1A and THRA.|Interaction with ESR1.|Interaction with VDR.|Interaction with GATA1 (By similarity).				androgen biosynthetic process|androgen receptor signaling pathway|cellular lipid metabolic process|fat cell differentiation|positive regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|transcription initiation from RNA polymerase II promoter	mediator complex	DNA binding|estrogen receptor binding|ligand-dependent nuclear receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|peroxisome proliferator activated receptor binding|receptor activity|retinoic acid receptor binding|RNA polymerase II transcription cofactor activity|thyroid hormone receptor binding|vitamin D receptor binding			lung(2)|ovary(2)|breast(1)|skin(1)|kidney(1)|pancreas(1)	8		Ovarian(249;1.78e-06)|Lung SC(565;0.0262)	Lung(15;0.0178)|LUAD - Lung adenocarcinoma(14;0.146)	UCEC - Uterine corpus endometrioid carcinoma (308;6.64e-05)|BRCA - Breast invasive adenocarcinoma(366;0.00136)|READ - Rectum adenocarcinoma(1115;0.0649)		TCTCAGGTGGTAATCTTGATGA	0.460										HNSCC(31;0.082)			410	15	---	---	---	---	
