Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CROCCL1	84809	broad.mit.edu	37	1	16946434	16946434	+	RNA	SNP	C	T	T	rs367060		TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr1:16946434C>T	uc010ocf.1	-	3		c.464G>A			CROCCL1_uc009vov.1_RNA|CROCCL1_uc001aze.2_RNA|CROCCL1_uc001azf.2_RNA					Homo sapiens mRNA for FLJ00313 protein.												0						CTCAGCCTTCCGCCGGGCCAG	0.672000													3	28	---	---	---	---	0	0	0.009096	0	0
NRAS	4893	broad.mit.edu	37	1	115256529	115256529	+	Missense_Mutation	SNP	T	C	C	rs11554290		TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr1:115256529T>C	uc009wgu.2	-	3	436	c.182A>G	c.(181-183)CAA>CGA	p.Q61R		NM_002524	NP_002515	P01111	RASN_HUMAN	neuroblastoma RAS viral (v-ras) oncogene homolog	61	GTP.		Q -> K (in neuroblastoma cell).		activation of MAPKK activity|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	Golgi membrane|plasma membrane	GTP binding|GTPase activity	p.Q61R(757)|p.Q61K(537)|p.Q61L(147)|p.Q61H(95)|p.Q61P(21)|p.Q61E(9)|p.Q61?(4)|p.Q61Q(3)|p.Q61_E62>HK(1)		haematopoietic_and_lymphoid_tissue(1008)|skin(956)|thyroid(334)|large_intestine(62)|NS(60)|soft_tissue(32)|lung(31)|upper_aerodigestive_tract(25)|urinary_tract(12)|liver(10)|adrenal_gland(9)|autonomic_ganglia(8)|testis(8)|central_nervous_system(8)|prostate(8)|breast(7)|biliary_tract(6)|ovary(6)|stomach(5)|pancreas(5)|endometrium(2)|kidney(2)|cervix(2)|eye(1)	2607	all_epithelial(7;5.11e-05)|all_lung(7;0.000179)|Lung NSC(6;0.00195)|Lung SC(450;0.211)	all_cancers(81;4.64e-07)|all_epithelial(167;4.2e-07)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		GTACTCTTCTTGTCCAGCTGT	0.458000	Q61L(HEPG2_LIVER)|Q61R(SKMEL2_SKIN)|Q61R(KMS27_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(IPC298_SKIN)|Q61P(TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(MHHES1_BONE)|Q61R(HT1197_URINARY_TRACT)|Q61L(MELJUSO_SKIN)|Q61R(ONS76_CENTRAL_NERVOUS_SYSTEM)|Q61R(KU1919_URINARY_TRACT)|Q61L(C3A_LIVER)|Q61R(TT2609C02_THYROID)|Q61R(NCIH2347_LUNG)|Q61L(KMS21BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(SW1271_LUNG)|Q61L(HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(MOLP8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)	50	Mis		melanoma|MM|AML|thyroid				Noonan_syndrome	TSP Lung(23;0.16)|Multiple Myeloma(1;<1E-6)			102	150	---	---	---	---	0	0	0.139131	0	0
ATF6	22926	broad.mit.edu	37	1	161816351	161816351	+	Missense_Mutation	SNP	A	T	T			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr1:161816351A>T	uc001gbr.2	+	10	1367	c.1300A>T	c.(1300-1302)ATC>TTC	p.I434F	ATF6_uc001gbq.1_Missense_Mutation_p.I434F	NM_007348	NP_031374	P18850	ATF6A_HUMAN	activating transcription factor 6	434	Lumenal (Potential).				positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response|protein folding	endoplasmic reticulum membrane|Golgi membrane|integral to membrane|nuclear envelope|nucleoplasm	protein dimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity			ovary(2)|skin(1)	3	all_hematologic(112;0.156)		BRCA - Breast invasive adenocarcinoma(70;0.00953)			AGATGGTATTATCCAGAAAAA	0.413000													4	102	---	---	---	---	0	0	0.009096	0	0
MAT1A	4143	broad.mit.edu	37	10	82036179	82036179	+	Missense_Mutation	SNP	C	T	T	rs147356286		TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr10:82036179C>T	uc001kbw.2	-	6	976	c.721G>A	c.(721-723)GTC>ATC	p.V241I		NM_000429	NP_000420	Q00266	METK1_HUMAN	methionine adenosyltransferase I, alpha	241					methylation|S-adenosylmethionine biosynthetic process|xenobiotic metabolic process	cytosol	ATP binding|metal ion binding|methionine adenosyltransferase activity				0			Colorectal(32;0.229)		L-Methionine(DB00134)|S-Adenosylmethionine(DB00118)	AGGTGGTAGACGGTGTCTTCG	0.592000													7	131	---	---	---	---	0	0	0.038147	0	0
AHNAK	79026	broad.mit.edu	37	11	62295549	62295549	+	Missense_Mutation	SNP	C	T	T	rs1298288		TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr11:62295549C>T	uc001ntl.2	-	5	6640	c.6340G>A	c.(6340-6342)GCC>ACC	p.A2114T	AHNAK_uc001ntk.1_Intron	NM_001620	NP_001611	Q09666	AHNK_HUMAN	AHNAK nucleoprotein isoform 1	2114					nervous system development	nucleus	protein binding			ovary(10)|pancreas(4)|skin(4)|upper_aerodigestive_tract(1)	19		Melanoma(852;0.155)				ATCTTGGGGGCCTTGAAGTGC	0.507000													6	372	---	---	---	---	0	0	0.029380	0	0
PC	5091	broad.mit.edu	37	11	66638642	66638642	+	Missense_Mutation	SNP	C	T	T			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr11:66638642C>T	uc001ojn.1	-	5	563	c.514G>A	c.(514-516)GCC>ACC	p.A172T	PC_uc001ojo.1_Missense_Mutation_p.A172T|PC_uc001ojp.1_Missense_Mutation_p.A172T	NM_022172	NP_071504	P11498	PYC_HUMAN	pyruvate carboxylase precursor	172	ATP-grasp.|Biotin carboxylation.				gluconeogenesis|lipid biosynthetic process	mitochondrial matrix	ATP binding|biotin binding|biotin carboxylase activity|metal ion binding|pyruvate carboxylase activity			ovary(2)|lung(1)|kidney(1)	4		Melanoma(852;0.0525)		Lung(977;0.153)|LUSC - Lung squamous cell carcinoma(976;0.227)	Biotin(DB00121)|Pyruvic acid(DB00119)	GTGATGGGGGCATCTGTGCCA	0.622000													12	130	---	---	---	---	0	0	0.093190	0	0
AMOTL1	154810	broad.mit.edu	37	11	94592844	94592844	+	Missense_Mutation	SNP	T	G	G			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr11:94592844T>G	uc001pfb.2	+	9	2269	c.2099T>G	c.(2098-2100)TTT>TGT	p.F700C	AMOTL1_uc001pfc.2_Missense_Mutation_p.F650C	NM_130847	NP_570899	Q8IY63	AMOL1_HUMAN	angiomotin like 1	700						cytoplasm|tight junction	identical protein binding			ovary(1)|breast(1)	2		Acute lymphoblastic leukemia(157;2.38e-05)|all_hematologic(158;0.00824)				ATCCGACACTTTGCCATGAAT	0.522000													3	21	---	---	---	---	0	0	0.009096	0	0
TBX5	6910	broad.mit.edu	37	12	114793765	114793765	+	Missense_Mutation	SNP	C	T	T			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr12:114793765C>T	uc001tvo.2	-	9	1624	c.1129G>A	c.(1129-1131)GCT>ACT	p.A377T	TBX5_uc001tvp.2_Missense_Mutation_p.A377T|TBX5_uc001tvq.2_Missense_Mutation_p.A327T	NM_181486	NP_852259	Q99593	TBX5_HUMAN	T-box 5 isoform 1	377					cardiac left ventricle formation|cell migration involved in coronary vasculogenesis|cell-cell signaling|embryonic arm morphogenesis|induction of apoptosis|negative regulation of cardiac muscle cell proliferation|negative regulation of cell migration|negative regulation of epithelial to mesenchymal transition|pericardium development|positive regulation of cardioblast differentiation|positive regulation of transcription from RNA polymerase II promoter|ventricular septum development	cytoplasm|nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding			ovary(6)|pancreas(1)|skin(1)	8	Medulloblastoma(191;0.163)|all_neural(191;0.178)			BRCA - Breast invasive adenocarcinoma(302;0.0893)		TACATGCAAGCTTGCCGCTGT	0.602000													62	89	---	---	---	---	0	0	0.139131	0	0
DNAH10	196385	broad.mit.edu	37	12	124408831	124408831	+	Missense_Mutation	SNP	T	C	C			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr12:124408831T>C	uc001uft.3	+	66	11289	c.11264T>C	c.(11263-11265)ATT>ACT	p.I3755T	DNAH10_uc001ufu.3_5'Flank	NM_207437	NP_997320	Q8IVF4	DYH10_HUMAN	dynein, axonemal, heavy chain 10	3755					microtubule-based movement	cilium axoneme|cytoplasm|dynein complex|microtubule	ATP binding|ATPase activity|microtubule motor activity			ovary(3)|skin(2)|central_nervous_system(1)	6	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;0.000207)|Epithelial(86;0.000556)|all cancers(50;0.00346)		TTAGGAAACATTTCCCTGGAG	0.413000													5	11	---	---	---	---	0	0	0.014758	0	0
PDILT	204474	broad.mit.edu	37	16	20395991	20395991	+	Missense_Mutation	SNP	T	C	C			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr16:20395991T>C	uc002dhc.1	-	3	608	c.385A>G	c.(385-387)AGG>GGG	p.R129G		NM_174924	NP_777584	Q8N807	PDILT_HUMAN	protein disulfide isomerase-like, testis	129					cell differentiation|cell redox homeostasis|multicellular organismal development|spermatogenesis	endoplasmic reticulum	isomerase activity			large_intestine(1)	1						GGCTCTGACCTGTTGCCCTCA	0.373000													5	245	---	---	---	---	0	0	0.014758	0	0
HS3ST2	9956	broad.mit.edu	37	16	22926609	22926609	+	Missense_Mutation	SNP	T	A	A			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr16:22926609T>A	uc002dli.2	+	2	902	c.830T>A	c.(829-831)CTC>CAC	p.L277H	HS3ST2_uc002dlj.2_RNA	NM_006043	NP_006034	Q9Y278	HS3S2_HUMAN	heparan sulfate D-glucosaminyl	277	Lumenal (Potential).					Golgi membrane|integral to membrane	[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity			ovary(1)|pancreas(1)	2				GBM - Glioblastoma multiforme(48;0.0299)		GGCGAGCGACTCATCACTGAC	0.557000													8	218	---	---	---	---	0	0	0.058154	0	0
BBS2	583	broad.mit.edu	37	16	56539933	56539933	+	Missense_Mutation	SNP	T	C	C			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr16:56539933T>C	uc002ejd.2	-	7	967	c.733A>G	c.(733-735)ATG>GTG	p.M245V	BBS2_uc010ccg.2_Missense_Mutation_p.M245V	NM_031885	NP_114091	Q9BXC9	BBS2_HUMAN	Bardet-Biedl syndrome 2 protein	245					adult behavior|brain morphogenesis|cerebral cortex development|cilium morphogenesis|fat cell differentiation|hippocampus development|melanosome transport|negative regulation of multicellular organism growth|photoreceptor cell maintenance|protein localization to organelle|regulation of cilium beat frequency involved in ciliary motility|sperm axoneme assembly|striatum development	BBSome|cilium membrane|microtubule basal body|motile cilium	protein binding			ovary(1)	1						TGAATGCTCATGGCATGATTT	0.343000									Bardet-Biedl_syndrome				4	76	---	---	---	---	0	0	0.009096	0	0
DHX8	1659	broad.mit.edu	37	17	41570183	41570183	+	Missense_Mutation	SNP	G	T	T			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr17:41570183G>T	uc002idu.1	+	6	711	c.638G>T	c.(637-639)CGG>CTG	p.R213L	DHX8_uc010wif.1_Missense_Mutation_p.R122L|DHX8_uc010wig.1_Missense_Mutation_p.R213L	NM_004941	NP_004932	Q14562	DHX8_HUMAN	DEAH (Asp-Glu-Ala-His) box polypeptide 8	213	Arg/Ser-rich (RS domain).					catalytic step 2 spliceosome	ATP binding|ATP-dependent RNA helicase activity|protein binding|RNA binding			ovary(2)|kidney(1)|pancreas(1)	4		Breast(137;0.00908)		BRCA - Breast invasive adenocarcinoma(366;0.08)		TCCAGGACCCGGGAGAGGAAT	0.373000													55	161	---	---	---	---	8.13277e-46	8.7834e-46	0.139131	1	0
DSC2	1824	broad.mit.edu	37	18	28662246	28662246	+	Silent	SNP	T	C	C			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr18:28662246T>C	uc002kwl.3	-	9	1675	c.1221A>G	c.(1219-1221)GTA>GTG	p.V407V	DSC2_uc002kwk.3_Silent_p.V407V	NM_024422	NP_077740	Q02487	DSC2_HUMAN	desmocollin 2 isoform Dsc2a preproprotein	407	Extracellular (Potential).|Cadherin 3.				homophilic cell adhesion	desmosome|integral to membrane	calcium ion binding			ovary(2)|skin(1)	3			OV - Ovarian serous cystadenocarcinoma(10;0.0241)			TGGCATCTGTTACAATTTTAA	0.308000													3	98	---	---	---	---	0	0	0.009096	0	0
MAPRE2	10982	broad.mit.edu	37	18	32677460	32677460	+	Silent	SNP	T	C	C			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr18:32677460T>C	uc002kyg.2	+	3	481	c.301T>C	c.(301-303)TTG>CTG	p.L101L	MAPRE2_uc010xcb.1_Silent_p.L58L|MAPRE2_uc010xcc.1_Silent_p.L89L|MAPRE2_uc002kyf.2_Silent_p.L101L|MAPRE2_uc002kyh.2_Silent_p.L48L|MAPRE2_uc010xcd.1_Silent_p.L58L	NM_014268	NP_055083	Q15555	MARE2_HUMAN	microtubule-associated protein, RP/EB family,	101	CH.				cell division|cell proliferation|mitosis|signal transduction	cytoplasm|microtubule	microtubule binding			ovary(1)	1						CTGCATTAGTTTGAAGAAAGT	0.403000													3	92	---	---	---	---	0	0	0.115264	0	0
PROC	5624	broad.mit.edu	37	2	128186036	128186036	+	Missense_Mutation	SNP	C	G	G	rs112356403		TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr2:128186036C>G	uc002tok.2	+	9	973	c.900C>G	c.(898-900)ATC>ATG	p.I300M	PROC_uc002tol.2_Missense_Mutation_p.I321M|PROC_uc010yzi.1_Missense_Mutation_p.I356M|PROC_uc010yzj.1_Missense_Mutation_p.I195M|PROC_uc010yzk.1_Missense_Mutation_p.I355M|PROC_uc002tom.2_Missense_Mutation_p.I334M	NM_000312	NP_000303	P04070	PROC_HUMAN	protein C	300	Peptidase S1.				blood coagulation|leukocyte migration|negative regulation of apoptosis|negative regulation of blood coagulation|peptidyl-glutamic acid carboxylation|post-translational protein modification|proteolysis	endoplasmic reticulum lumen|Golgi lumen|plasma membrane	calcium ion binding|protein binding|serine-type endopeptidase activity				0	Colorectal(110;0.1)			BRCA - Breast invasive adenocarcinoma(221;0.0673)	Antihemophilic Factor(DB00025)|Drotrecogin alfa(DB00055)|Menadione(DB00170)|Sodium Tetradecyl Sulfate(DB00464)	ACAATGACATCGCACTGCTGC	0.632000													3	103	---	---	---	---	0	0	0.115264	0	0
ZRANB3	84083	broad.mit.edu	37	2	136026599	136026599	+	Missense_Mutation	SNP	A	G	G			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr2:136026599A>G	uc002tum.2	-	11	1436	c.1319T>C	c.(1318-1320)GTG>GCG	p.V440A	ZRANB3_uc002tuk.2_5'UTR|ZRANB3_uc002tul.2_Missense_Mutation_p.V440A|ZRANB3_uc002tun.1_3'UTR	NM_032143	NP_115519	Q5FWF4	ZRAB3_HUMAN	zinc finger, RAN-binding domain containing 3	440	Helicase C-terminal.					intracellular	ATP binding|DNA binding|endonuclease activity|helicase activity|zinc ion binding			lung(2)	2				BRCA - Breast invasive adenocarcinoma(221;0.135)		GTGAATATTCACAGAACTGCA	0.423000													8	194	---	---	---	---	0	0	0.058154	0	0
LPP	4026	broad.mit.edu	37	3	188584007	188584007	+	Missense_Mutation	SNP	A	G	G			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr3:188584007A>G	uc003frs.1	+	9	1676	c.1430A>G	c.(1429-1431)AAT>AGT	p.N477S	LPP_uc011bsg.1_Missense_Mutation_p.N330S|LPP_uc011bsi.1_Missense_Mutation_p.N477S|LPP_uc011bsj.1_Missense_Mutation_p.N314S	NM_005578	NP_005569	Q93052	LPP_HUMAN	LIM domain containing preferred translocation	477	LIM zinc-binding 2.				cell adhesion	cytoplasm|focal adhesion|nucleus	protein binding|zinc ion binding		HMGA2/LPP(161)	soft_tissue(134)|bone(27)|lung(2)|ovary(1)|breast(1)	165	all_cancers(143;1.37e-09)|all_hematologic(3;0.0429)|Ovarian(172;0.088)	all_lung(153;0.00139)|Lung NSC(153;0.00202)		GBM - Glioblastoma multiforme(93;0.00602)		GAGCAGTGCAATGTGTGTTCC	0.532000			T	HMGA2|MLL|C12orf9	lipoma|leukemia								35	48	---	---	---	---	0	0	0.064281	0	0
FBN2	2201	broad.mit.edu	37	5	127637170	127637170	+	Missense_Mutation	SNP	C	T	T			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr5:127637170C>T	uc003kuu.2	-	47	6389	c.5950G>A	c.(5950-5952)GTG>ATG	p.V1984M		NM_001999	NP_001990	P35556	FBN2_HUMAN	fibrillin 2 precursor	1984	EGF-like 33; calcium-binding.				bone trabecula formation|negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta|positive regulation of bone mineralization|positive regulation of osteoblast differentiation	microfibril	calcium ion binding|extracellular matrix structural constituent			ovary(8)|large_intestine(4)|pancreas(1)|kidney(1)|skin(1)	15		all_cancers(142;0.0216)|Prostate(80;0.0551)	KIRC - Kidney renal clear cell carcinoma(527;0.0268)|Kidney(363;0.0488)	OV - Ovarian serous cystadenocarcinoma(64;0.0821)|Epithelial(69;0.146)		TTTCTGCACACCTGACCAAAA	0.368000													6	134	---	---	---	---	0	0	0.038147	0	0
LAMA4	3910	broad.mit.edu	37	6	112462655	112462655	+	Silent	SNP	G	A	A			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr6:112462655G>A	uc003pvu.2	-	21	3027	c.2718C>T	c.(2716-2718)TAC>TAT	p.Y906Y	LAMA4_uc003pvv.2_Silent_p.Y899Y|LAMA4_uc003pvt.2_Silent_p.Y899Y	NM_001105206	NP_001098676	Q16363	LAMA4_HUMAN	laminin, alpha 4 isoform 1 precursor	906	Laminin G-like 1.				cell adhesion|regulation of cell adhesion|regulation of cell migration|regulation of embryonic development	laminin-1 complex	extracellular matrix structural constituent|receptor binding			ovary(4)|breast(2)|large_intestine(1)|central_nervous_system(1)|pancreas(1)	9		all_cancers(87;0.000196)|all_hematologic(75;0.000114)|all_epithelial(87;0.00542)|Colorectal(196;0.0209)		all cancers(137;0.0335)|OV - Ovarian serous cystadenocarcinoma(136;0.0578)|Epithelial(106;0.0748)|BRCA - Breast invasive adenocarcinoma(108;0.242)		AATTATAGACGTATACCAGAT	0.368000													26	62	---	---	---	---	0	0	0.091800	0	0
POM121	9883	broad.mit.edu	37	7	72398976	72398976	+	Missense_Mutation	SNP	A	G	G	rs147859349		TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr7:72398976A>G	uc003twk.2	+	4	1076	c.1076A>G	c.(1075-1077)AAT>AGT	p.N359S	POM121_uc003twj.2_Missense_Mutation_p.N94S|POM121_uc010lam.1_Missense_Mutation_p.N94S	NM_172020	NP_742017	Q96HA1	P121A_HUMAN	nuclear pore membrane protein 121	359	Pore side (Potential).				carbohydrate metabolic process|glucose transport|mRNA transport|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	endoplasmic reticulum membrane|nuclear membrane|nuclear pore					0		Lung NSC(55;0.163)				CTGGTGGCCAATGGAGTCCCC	0.468000													5	325	---	---	---	---	0	0	0.014758	0	0
SRPK2	6733	broad.mit.edu	37	7	104786953	104786953	+	Silent	SNP	A	T	T			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr7:104786953A>T	uc003vct.2	-	7	928	c.741T>A	c.(739-741)CCT>CCA	p.P247P	SRPK2_uc003vcu.2_Silent_p.P247P|SRPK2_uc003vcv.2_Silent_p.P258P|SRPK2_uc003vcw.1_Silent_p.P247P	NM_182691	NP_872633	P78362	SRPK2_HUMAN	serine/arginine-rich protein-specific kinase 2	247	Protein kinase.				angiogenesis|cell differentiation|intracellular protein kinase cascade|negative regulation of viral genome replication|nuclear speck organization|positive regulation of cell cycle|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of neuron apoptosis|positive regulation of viral genome replication|spliceosome assembly	cytoplasm|nucleolus	14-3-3 protein binding|ATP binding|magnesium ion binding|protein serine/threonine kinase activity			central_nervous_system(3)|ovary(2)|upper_aerodigestive_tract(1)	6						CAGACCCTGAAGGAGGAGGAG	0.498000													8	44	---	---	---	---	0	0	0.047766	0	0
Unknown	0	broad.mit.edu	37	12	33452396	33452397	+	IGR	INS	-	AAGG	AAGG	rs143444187	by1000genomes	TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr12:33452396_33452397insAAGG								PKP2 (402616 upstream) : SYT10 (75951 downstream)																							gaaagaaaggaaaggaaggaag	0.000													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	17	8102779	8102779	+	IGR	DEL	A	-	-			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr17:8102779delA								C17orf59 (9215 upstream) : AURKB (5271 downstream)																							TCCCTGGCCTATTTTTTTTTT	0.358													4	9	---	---	---	---					
Unknown	0	broad.mit.edu	37	18	11625378	11625379	+	IGR	INS	-	A	A			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr18:11625378_11625379insA								FAM38B (923399 upstream) : GNAL (63757 downstream)																							CTCTTCCCCCGAAAAATGACAA	0.317													4	2	---	---	---	---					
Unknown	0	broad.mit.edu	37	19	53833828	53833830	+	IGR	DEL	AAG	-	-	rs71185865		TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr19:53833828_53833830delAAG								BIRC8 (38953 upstream) : ZNF845 (3172 downstream)																							aaaaaaaaaaaagaaaagaaaag	0.187													3	6	---	---	---	---					
Unknown	0	broad.mit.edu	37	20	2056544	2056565	+	IGR	DEL	ACACACACACACACACACACAC	-	-	rs72165579		TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr20:2056544_2056565delACACACACACACACACACACAC								PDYN (81841 upstream) : STK35 (25963 downstream)																							AAAAAAAAATacacacacacacacacacacacacacacacac	0.162													4	7	---	---	---	---					
Unknown	0	broad.mit.edu	37	4	19889191	19889191	+	IGR	DEL	C	-	-			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr4:19889191delC								None (None upstream) : SLIT2 (366044 downstream)																							ggtgccaaaacccaggagggg	0.000													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	4	154050665	154050665	+	IGR	DEL	A	-	-			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr4:154050665delA								FHDC1 (149817 upstream) : TRIM2 (23605 downstream)																							caccatcaccaccaccaccac	0.000													3	5	---	---	---	---					
Unknown	0	broad.mit.edu	37	5	74285945	74285946	+	IGR	INS	-	T	T			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr5:74285945_74285946insT								FAM169A (94157 upstream) : GCNT4 (37344 downstream)																							taattgctttcttttttttttt	0.183													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	8	21390989	21390989	+	IGR	DEL	G	-	-			TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr8:21390989delG								None (None upstream) : GFRA2 (158541 downstream)																							aaggaaggaaggaaggaagga	0.000													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	8	116686698	116686699	+	IGR	INS	-	CCTC	CCTC	rs142743732	by1000genomes	TCGA-BJ-A0ZA-01A-11D-A10S-08	TCGA-BJ-A0ZA-10A-02D-A10S-08									Somatic	Phase_I	Capture				Illumina GAIIx	937b098e-73d8-4b69-be9c-552ca283f22e	85111d55-aad8-4fd5-8b75-f9ba222ba71a	g.chr8:116686698_116686699insCCTC								TRPS1 (5470 upstream) : EIF3H (970357 downstream)																							cttccttccttcctccctccct	0.124													4	3	---	---	---	---					
